In order to study the electronic structure and the variation of chemical shift of the <sup>181</sup>Ta nuclei in ternary A<sub>3</sub>BC<sub>4</sub> semiconductor, the first-princip...In order to study the electronic structure and the variation of chemical shift of the <sup>181</sup>Ta nuclei in ternary A<sub>3</sub>BC<sub>4</sub> semiconductor, the first-principles calculations are used by PBE-GGA, BJ, and TB-mBJ functionals. By comparing these three kinds of functionals, the results of TB-mBJ are more in line with the experimental values. The electronic structure calculated by TB-mBJ functional shows that TaCu<sub>3</sub>X<sub>4</sub> (X = S, Se, Te) are indirect bandgap semiconductors and TaTl<sub>3</sub>X<sub>4</sub> (X = S, Se) are direct bandgap semiconductors. By decomposing the chemical shifts contributed by the different orbitals, we found that the chemical shifts are related to the electronic structure. In this paper, the variation (up to 2500 ppm) of NMR chemical shift of 181Ta nuclei is related to the d orbital of Ta.展开更多
LTE-A系统在传输用户业务数据时ESM子层即不能实时管理物理承载的使用,也不能实现上行数据流模板UL-TFT(Uplink Traffic Flow Template)的功能。为了正确传输用户数据并获得相应的业务的服务质量Qo S(Quality of Service),在用户平面中...LTE-A系统在传输用户业务数据时ESM子层即不能实时管理物理承载的使用,也不能实现上行数据流模板UL-TFT(Uplink Traffic Flow Template)的功能。为了正确传输用户数据并获得相应的业务的服务质量Qo S(Quality of Service),在用户平面中增加承载控制实体BC,通过对UL-TFT和EPS承载路由信息管理进行设计,搭建基于TTCN-3(Testing and Test Control Notation version 3)测试系统的终端无线资源管理(RRM)一致性测试平台,对流程设计进行验证。与UMTS系统相比,利用多实体管理技术,承载建立和业务数据传输的时延明显减少。展开更多
Kaposi sarcoma-associated herpesvirus(KSHV)triggers the development of Kaposi sarcoma,a skin malignancy that is one of the most widespread defining symptoms in acquired immunodeficiency syndrome patients.KSHV manifest...Kaposi sarcoma-associated herpesvirus(KSHV)triggers the development of Kaposi sarcoma,a skin malignancy that is one of the most widespread defining symptoms in acquired immunodeficiency syndrome patients.KSHV manifests in two distinct cycles,a chronic latent cycle and an acute lytic cycle.Current clinical anti-herpesvirus therapeutic agents are predominantly composed of nucleoside analogues that target viral replication in the lytic cycle only,while KSHV latent genes are at the basis tumorigenesis.Currently,there are no effective therapies targeting latent KSHV infections.Therefore,the aim of this study was to identify putative therapeutic compounds with inhibitory activity against latent KSHV.The KSHV-infected primary effusion lymphoma cell line BC-3 was used to study antiviral activity of glycyrrhizic acid(GA),Allicin,and epigallocatechin-3-gallate(EGCG)against latent and lytic KSHV.Activity of GA,Allicin,EGCG,and the established anti-lytic cycle control compound ganciclovir was quantified by real-time polymerase chain reaction of nuclear and virion KSHV DNA yields after treatment compared with the untreated control.GA and Allicin showed antiviral activity against both latent and lytic KSHV,while EGCG displayed activity against lytic KSHV only.Therefore,GA and Allicin are interesting compounds for further development of anti-KSHV therapy against latent cycle infections.展开更多
文摘In order to study the electronic structure and the variation of chemical shift of the <sup>181</sup>Ta nuclei in ternary A<sub>3</sub>BC<sub>4</sub> semiconductor, the first-principles calculations are used by PBE-GGA, BJ, and TB-mBJ functionals. By comparing these three kinds of functionals, the results of TB-mBJ are more in line with the experimental values. The electronic structure calculated by TB-mBJ functional shows that TaCu<sub>3</sub>X<sub>4</sub> (X = S, Se, Te) are indirect bandgap semiconductors and TaTl<sub>3</sub>X<sub>4</sub> (X = S, Se) are direct bandgap semiconductors. By decomposing the chemical shifts contributed by the different orbitals, we found that the chemical shifts are related to the electronic structure. In this paper, the variation (up to 2500 ppm) of NMR chemical shift of 181Ta nuclei is related to the d orbital of Ta.
文摘LTE-A系统在传输用户业务数据时ESM子层即不能实时管理物理承载的使用,也不能实现上行数据流模板UL-TFT(Uplink Traffic Flow Template)的功能。为了正确传输用户数据并获得相应的业务的服务质量Qo S(Quality of Service),在用户平面中增加承载控制实体BC,通过对UL-TFT和EPS承载路由信息管理进行设计,搭建基于TTCN-3(Testing and Test Control Notation version 3)测试系统的终端无线资源管理(RRM)一致性测试平台,对流程设计进行验证。与UMTS系统相比,利用多实体管理技术,承载建立和业务数据传输的时延明显减少。
基金supported by the Natural Science Foundation of China(81500491)the National Science Foundation of China(Key Program,2017ZX10202102,2018ZX10715014).
文摘Kaposi sarcoma-associated herpesvirus(KSHV)triggers the development of Kaposi sarcoma,a skin malignancy that is one of the most widespread defining symptoms in acquired immunodeficiency syndrome patients.KSHV manifests in two distinct cycles,a chronic latent cycle and an acute lytic cycle.Current clinical anti-herpesvirus therapeutic agents are predominantly composed of nucleoside analogues that target viral replication in the lytic cycle only,while KSHV latent genes are at the basis tumorigenesis.Currently,there are no effective therapies targeting latent KSHV infections.Therefore,the aim of this study was to identify putative therapeutic compounds with inhibitory activity against latent KSHV.The KSHV-infected primary effusion lymphoma cell line BC-3 was used to study antiviral activity of glycyrrhizic acid(GA),Allicin,and epigallocatechin-3-gallate(EGCG)against latent and lytic KSHV.Activity of GA,Allicin,EGCG,and the established anti-lytic cycle control compound ganciclovir was quantified by real-time polymerase chain reaction of nuclear and virion KSHV DNA yields after treatment compared with the untreated control.GA and Allicin showed antiviral activity against both latent and lytic KSHV,while EGCG displayed activity against lytic KSHV only.Therefore,GA and Allicin are interesting compounds for further development of anti-KSHV therapy against latent cycle infections.
