In recent years,many phase space distributions have been proposed,and one of the more independently interesting is the Bai distribution function(BDF).The BDF has been shown to interpolate between the instantaneous aut...In recent years,many phase space distributions have been proposed,and one of the more independently interesting is the Bai distribution function(BDF).The BDF has been shown to interpolate between the instantaneous auto-correlation function and the Wigner distribution function,and be applied in linear frequency modulated signal parameter estimation and optical partial coherence areas.Currently,the BDF is only defined for continuous signals.However,for both simulation and experimental purposes,the signals must be discrete.This necessitates the development of a BDF analysis workflow for discrete signals.In this work,we analyze the sampling requirements imposed by the BDF and demonstrate their correctness by comparing the continuous BDFs of continuous test signals with their numerically approximated counterparts.Our results permit more accurate simulations using BDFs,which will be useful in applying them to problems such as partial coherence.展开更多
In the present study, we explored the therapeutic potential of Cang Zhu-Huang Bai (CZ-HB) against rheumatoid arthritis (RA) and elucidated the associated mechanisms. The approach involved a systematic examination of t...In the present study, we explored the therapeutic potential of Cang Zhu-Huang Bai (CZ-HB) against rheumatoid arthritis (RA) and elucidated the associated mechanisms. The approach involved a systematic examination of the chemical ingredients of CZ-HB using TCMSP database. Subsequently, we predicted the targets corresponding to the active ingredients through the SwissTargetPrediction database. We constructed a comprehensive drug-ingredient-target network using Cytoscape (v 3.8.0), with the main ingredients of the drugs identified based on their degree values. We conducted a meticulous search across GEO, GeneCards, Therapeutic Target Database (TTD), and PharmGkb databases to identify target proteins associated with RA. The intersection of targets corresponding to the drugs' active ingredients and those associated with RA provided crucial insights. Functional analysis, including GO and KEGG pathway enrichment analyses, was performed on the intersecting targets using R (v 4.2.2). Additionally, a protein-protein interaction (PPI) network of the intersecting targets was constructed using the String platform. The resulting drug-ingredient-target-disease topology network was visualized using Cytoscape (v 3.8.0), and the Cytohubba plugin facilitated the identification of hub genes. The study revealed 35 active ingredients of CZ-HB and their corresponding 673 targets. We identified 14 major active ingredients crucial to the drug’s effects by focusing on the degree values. Furthermore, our investigation uncovered 784 targets associated with RA. Through the intersection of drug and disease targets, we pinpointed 34 active ingredients of CZ-HB capable of acting on 126 targets implicated in RA. The topological network analysis of the intersected genes identified five hub genes. The binding affinity of these hub genes to the 14 primary active ingredients of the drug was confirmed through molecular docking. The enrichment results of the intersecting genes suggested that CZ-HB exerted its anti-RA effects through a multi-component, multi-target, and multi-pathway approach.展开更多
This essay endeavors to dispel the lingering misconception that Li Bai,the celebrated Tang Dynasty poet,was a man devoid of propriety.Through a meticulous examination of historical records,literary works,and contempor...This essay endeavors to dispel the lingering misconception that Li Bai,the celebrated Tang Dynasty poet,was a man devoid of propriety.Through a meticulous examination of historical records,literary works,and contemporary interpretations,this study presents a nuanced portrait of Li Bai as a poet who,despite his eccentricities and wanderlust,possessed a profound sense of etiquette and respect for societal norms.This essay argues that his unique personality in life and free expression in poetry are all driven by the need for artistic creation,rather than challenging for ancient propriety.展开更多
Metonymy is not only regarded as a figure of speech,but also an important cognitive instrument of human beings.There are many types of metonymies in Li Bai's poems.Metonymy can make the language vivid and reflect ...Metonymy is not only regarded as a figure of speech,but also an important cognitive instrument of human beings.There are many types of metonymies in Li Bai's poems.Metonymy can make the language vivid and reflect poet's mode of knowing and thinking about the world.This paper proposes five strategies for translation of metonymy in Li Bai's poems from the perspective of cognitive linguis tics.展开更多
Based on the poem Xiatian Hai Hen Yuan夏天还很远, one of the most characteristic works of the Chinese poet Bai Hua, along with its four English translations, this paper conducts comparative textual studies with regard...Based on the poem Xiatian Hai Hen Yuan夏天还很远, one of the most characteristic works of the Chinese poet Bai Hua, along with its four English translations, this paper conducts comparative textual studies with regard to three aspects, including the translation of hidden personae, the selection of the tense and aspectas well as the rendition of poetic rhythms. The author holds the view that, on the one hand, different textual interpretations have gone a long way toward the dissemination of the original poem in the English-speaking world;on the other hand, the translator's proper understanding and rendition is of great significance with a view to a better presentation of the unique beauty of Chinese poetry both in the content and the form.展开更多
基金the support of the University College Dublin through a John Sheridan Scholarship.Min Wan thanks 4TU.RECENTRE program(Award No.OA102070)the National Growth Fund programme PhotonDelta in The Netherlands.
文摘In recent years,many phase space distributions have been proposed,and one of the more independently interesting is the Bai distribution function(BDF).The BDF has been shown to interpolate between the instantaneous auto-correlation function and the Wigner distribution function,and be applied in linear frequency modulated signal parameter estimation and optical partial coherence areas.Currently,the BDF is only defined for continuous signals.However,for both simulation and experimental purposes,the signals must be discrete.This necessitates the development of a BDF analysis workflow for discrete signals.In this work,we analyze the sampling requirements imposed by the BDF and demonstrate their correctness by comparing the continuous BDFs of continuous test signals with their numerically approximated counterparts.Our results permit more accurate simulations using BDFs,which will be useful in applying them to problems such as partial coherence.
基金National Natural Science Foundations of China (Grant No. 81960863)the Education Department of Yunnan Province (Grant No. 2023Y0463)。
文摘In the present study, we explored the therapeutic potential of Cang Zhu-Huang Bai (CZ-HB) against rheumatoid arthritis (RA) and elucidated the associated mechanisms. The approach involved a systematic examination of the chemical ingredients of CZ-HB using TCMSP database. Subsequently, we predicted the targets corresponding to the active ingredients through the SwissTargetPrediction database. We constructed a comprehensive drug-ingredient-target network using Cytoscape (v 3.8.0), with the main ingredients of the drugs identified based on their degree values. We conducted a meticulous search across GEO, GeneCards, Therapeutic Target Database (TTD), and PharmGkb databases to identify target proteins associated with RA. The intersection of targets corresponding to the drugs' active ingredients and those associated with RA provided crucial insights. Functional analysis, including GO and KEGG pathway enrichment analyses, was performed on the intersecting targets using R (v 4.2.2). Additionally, a protein-protein interaction (PPI) network of the intersecting targets was constructed using the String platform. The resulting drug-ingredient-target-disease topology network was visualized using Cytoscape (v 3.8.0), and the Cytohubba plugin facilitated the identification of hub genes. The study revealed 35 active ingredients of CZ-HB and their corresponding 673 targets. We identified 14 major active ingredients crucial to the drug’s effects by focusing on the degree values. Furthermore, our investigation uncovered 784 targets associated with RA. Through the intersection of drug and disease targets, we pinpointed 34 active ingredients of CZ-HB capable of acting on 126 targets implicated in RA. The topological network analysis of the intersected genes identified five hub genes. The binding affinity of these hub genes to the 14 primary active ingredients of the drug was confirmed through molecular docking. The enrichment results of the intersecting genes suggested that CZ-HB exerted its anti-RA effects through a multi-component, multi-target, and multi-pathway approach.
基金supported by the projects:“Research on Classical Poetry and Cultural Identity Education for International Students in China(2023ZJY2071)”“Research on Establishing Chinese Cultural Symbols and Chinese National Images Shared by All Ethnic Groups”(ZK202410)+3 种基金Wuzhou University Education and Teaching Reform Project“Research on Innovative Teaching Mode and Evaluation of‘Poetry and Ritual Interaction’Under the Background of Skill and Emotional Deficiency(Wyjg2022A033)”“Research on Improving the Quality of Ancient Literature Curriculum Centered on Student Cognitive Ladder(Wyjg2023B016)”“Research on Innovative Integration of Information Technology and Ancient Literature Curriculum Under the Goal of New Literature Construction(Wyjg2024A018)”2022 Chinese Ancient Literature Course Ideological and Political Selection Project of Wuzhou University.
文摘This essay endeavors to dispel the lingering misconception that Li Bai,the celebrated Tang Dynasty poet,was a man devoid of propriety.Through a meticulous examination of historical records,literary works,and contemporary interpretations,this study presents a nuanced portrait of Li Bai as a poet who,despite his eccentricities and wanderlust,possessed a profound sense of etiquette and respect for societal norms.This essay argues that his unique personality in life and free expression in poetry are all driven by the need for artistic creation,rather than challenging for ancient propriety.
文摘Metonymy is not only regarded as a figure of speech,but also an important cognitive instrument of human beings.There are many types of metonymies in Li Bai's poems.Metonymy can make the language vivid and reflect poet's mode of knowing and thinking about the world.This paper proposes five strategies for translation of metonymy in Li Bai's poems from the perspective of cognitive linguis tics.
文摘Based on the poem Xiatian Hai Hen Yuan夏天还很远, one of the most characteristic works of the Chinese poet Bai Hua, along with its four English translations, this paper conducts comparative textual studies with regard to three aspects, including the translation of hidden personae, the selection of the tense and aspectas well as the rendition of poetic rhythms. The author holds the view that, on the one hand, different textual interpretations have gone a long way toward the dissemination of the original poem in the English-speaking world;on the other hand, the translator's proper understanding and rendition is of great significance with a view to a better presentation of the unique beauty of Chinese poetry both in the content and the form.
