The aim of the present study was to evaluate whether tissue levels of vitamin B complex and vitamin B12 were altered after crush-induced peripheral nerve injury in an experimental rat model. A total of 80 male Wistar ...The aim of the present study was to evaluate whether tissue levels of vitamin B complex and vitamin B12 were altered after crush-induced peripheral nerve injury in an experimental rat model. A total of 80 male Wistar rats were randomized into one control（n = 8） and six study groups（1, 6, 12, 24 hours, 3, and 7 days after experimental nerve injury; n = 12 for each group）. Crush-induced peripheral nerve injury was performed on the sciatic nerves of rats in six study groups. Tissue samples from the sites of peripheral nerve injury were obtained at 1, 6, 12, 24 hours, 3 and 7 days after experimental nerve injury. Enzyme-linked immunosorbent assay results showed that tissue levels of vitamin B complex and vitamin B12 in the injured sciatic nerve were significantly greater at 1 and 12 hours after experimental nerve injury, while they were significantly lower at 7 days than in control group. Tissue level of vitamin B_（12） in the injured sciatic nerve was significantly lower at 1, 6, 12 and 24 hours than in the control group. These results suggest that tissue levels of vitamin B complex and vitamin B12 vary with progression of crush-induced peripheral nerve injury, and supplementation of these vitamins in the acute period may be beneficial for acceleration of nerve regeneration.展开更多
10月4日-9日,2025年比利时世界客车博览会(Busworld Europe 2025)在布鲁塞尔举行。比亚迪携三款基于e-BUS平台3.0重磅打造的新品全球首秀:高地板纯电动大巴B12.b HF、低入口纯电动大巴B12.b LE和18米纯电动铰接车B18.b;及主流车型纯电...10月4日-9日,2025年比利时世界客车博览会(Busworld Europe 2025)在布鲁塞尔举行。比亚迪携三款基于e-BUS平台3.0重磅打造的新品全球首秀:高地板纯电动大巴B12.b HF、低入口纯电动大巴B12.b LE和18米纯电动铰接车B18.b;及主流车型纯电动大巴B12.b、B13.b在内的共五款车型和一款12米高地板大巴底盘一同震撼亮相,为欧洲公共交通绿色出行带来更安全、更高效的整体性解决方案。展开更多
文摘The aim of the present study was to evaluate whether tissue levels of vitamin B complex and vitamin B12 were altered after crush-induced peripheral nerve injury in an experimental rat model. A total of 80 male Wistar rats were randomized into one control（n = 8） and six study groups（1, 6, 12, 24 hours, 3, and 7 days after experimental nerve injury; n = 12 for each group）. Crush-induced peripheral nerve injury was performed on the sciatic nerves of rats in six study groups. Tissue samples from the sites of peripheral nerve injury were obtained at 1, 6, 12, 24 hours, 3 and 7 days after experimental nerve injury. Enzyme-linked immunosorbent assay results showed that tissue levels of vitamin B complex and vitamin B12 in the injured sciatic nerve were significantly greater at 1 and 12 hours after experimental nerve injury, while they were significantly lower at 7 days than in control group. Tissue level of vitamin B_（12） in the injured sciatic nerve was significantly lower at 1, 6, 12 and 24 hours than in the control group. These results suggest that tissue levels of vitamin B complex and vitamin B12 vary with progression of crush-induced peripheral nerve injury, and supplementation of these vitamins in the acute period may be beneficial for acceleration of nerve regeneration.
文摘10月4日-9日,2025年比利时世界客车博览会(Busworld Europe 2025)在布鲁塞尔举行。比亚迪携三款基于e-BUS平台3.0重磅打造的新品全球首秀:高地板纯电动大巴B12.b HF、低入口纯电动大巴B12.b LE和18米纯电动铰接车B18.b;及主流车型纯电动大巴B12.b、B13.b在内的共五款车型和一款12米高地板大巴底盘一同震撼亮相,为欧洲公共交通绿色出行带来更安全、更高效的整体性解决方案。
