The prevalence of cardiometabolic syndrome(CMS)and increasing mortality rate play a significant role in the global increase of cardiovascular disease(CVD)in developing countries.A group of metabolic syndromes that are...The prevalence of cardiometabolic syndrome(CMS)and increasing mortality rate play a significant role in the global increase of cardiovascular disease(CVD)in developing countries.A group of metabolic syndromes that are risk factors for CVDs are referred to as the CMS.Although the exact mechanism(s)behind the development of the CMS are not known,but multi-organ insulin resistance,a prevalent characteristic of the syndrome,is probably one of them.The two most prevalent dental diseases i.e.periodontitis(PD)and dental caries have been re-lated to several systemic diseases and disorders,such as CMS.Age,alcohol con-sumption,being obese,possessing diabetes,as well as smoking are risk factors for periodontal diseases,while both CVD and periodontal diseases are linked to systemic inflammation.It has a multifactorial aetiology and is associated with many systemic diseases.When bacteria and their products attack the periodontal tissues,the tissue raises an immune-inflammatory response against the patho-gens.This acute phase response is a result of the pathogen’s systemic attack and contributes to the overall inflammatory burden of the system.CVD and PD are both diseases associated with systemic inflammation and may be related as they share many common risk factors.Hence,the correlation between these conditions might also have an impact on how dentistry and medicine are practised,thus helping to build a working relationship between the dentist and the physician.展开更多
Objectives:Distolingual root of the permanent mandibular first molar(PMFM-DLR)has been frequently reported,which may complicate the treatment of periodontitis.This study aimed to assess the morphological features of P...Objectives:Distolingual root of the permanent mandibular first molar(PMFM-DLR)has been frequently reported,which may complicate the treatment of periodontitis.This study aimed to assess the morphological features of PMFM-DLR and investigate the correlation between the morphological features of PMFM-DLR and periodontal status in patients with Eastern Chinese ethnic background.Materials and methods:A total of 836 cone beam computed tomography(CBCT)images with 1497 mandibular first molars were analyzed to observe the prevalence of PMFM-DLR at the patients and tooth levels in Eastern China.Among them,complete periodontal charts were available for 69 Chinese patients with 103 teeth.Correlation and regression analyses were used to evaluate the correlation between the morphological features of DLR,bone loss,and periodontal clinical parameters,including clinical attachment loss(CAL),probing pocket depth(PPD),gingival recession(GR),and furcation involvement(FI).Results:The patient-level prevalence and tooth-level prevalence of DLR in mandibular first molars were 29.4%and 26.3%,respectively.Multiple linear regression analysis suggested that bone loss at the lingual site and CAL were negatively affected by the angle of separation between distolingual and mesial roots in the transverse section,while they were significantly influenced by age and the angle of separation between distobuccal and mesial roots in the coronal section.Conclusions:The prevalence of PMFM-DLR in Eastern China was relatively high in our cohort.The morphological features of DLR were correlated with the periodontal status of mandibular first molars.This study provides critical information on the morphological features of DLR for improved diagnosis and treatment options of mandibular molars with DLR.展开更多
文摘The prevalence of cardiometabolic syndrome(CMS)and increasing mortality rate play a significant role in the global increase of cardiovascular disease(CVD)in developing countries.A group of metabolic syndromes that are risk factors for CVDs are referred to as the CMS.Although the exact mechanism(s)behind the development of the CMS are not known,but multi-organ insulin resistance,a prevalent characteristic of the syndrome,is probably one of them.The two most prevalent dental diseases i.e.periodontitis(PD)and dental caries have been re-lated to several systemic diseases and disorders,such as CMS.Age,alcohol con-sumption,being obese,possessing diabetes,as well as smoking are risk factors for periodontal diseases,while both CVD and periodontal diseases are linked to systemic inflammation.It has a multifactorial aetiology and is associated with many systemic diseases.When bacteria and their products attack the periodontal tissues,the tissue raises an immune-inflammatory response against the patho-gens.This acute phase response is a result of the pathogen’s systemic attack and contributes to the overall inflammatory burden of the system.CVD and PD are both diseases associated with systemic inflammation and may be related as they share many common risk factors.Hence,the correlation between these conditions might also have an impact on how dentistry and medicine are practised,thus helping to build a working relationship between the dentist and the physician.
基金The study protocol has been reviewed and approved by the Ethics Committee of the Stomatology Hospital,Zhejiang University School of Medicine(No.2023-031)and registered in Chinese Clinical Trial Registry(No.ChiCTR2300074445).
文摘Objectives:Distolingual root of the permanent mandibular first molar(PMFM-DLR)has been frequently reported,which may complicate the treatment of periodontitis.This study aimed to assess the morphological features of PMFM-DLR and investigate the correlation between the morphological features of PMFM-DLR and periodontal status in patients with Eastern Chinese ethnic background.Materials and methods:A total of 836 cone beam computed tomography(CBCT)images with 1497 mandibular first molars were analyzed to observe the prevalence of PMFM-DLR at the patients and tooth levels in Eastern China.Among them,complete periodontal charts were available for 69 Chinese patients with 103 teeth.Correlation and regression analyses were used to evaluate the correlation between the morphological features of DLR,bone loss,and periodontal clinical parameters,including clinical attachment loss(CAL),probing pocket depth(PPD),gingival recession(GR),and furcation involvement(FI).Results:The patient-level prevalence and tooth-level prevalence of DLR in mandibular first molars were 29.4%and 26.3%,respectively.Multiple linear regression analysis suggested that bone loss at the lingual site and CAL were negatively affected by the angle of separation between distolingual and mesial roots in the transverse section,while they were significantly influenced by age and the angle of separation between distobuccal and mesial roots in the coronal section.Conclusions:The prevalence of PMFM-DLR in Eastern China was relatively high in our cohort.The morphological features of DLR were correlated with the periodontal status of mandibular first molars.This study provides critical information on the morphological features of DLR for improved diagnosis and treatment options of mandibular molars with DLR.
