Corrosion activities and related accidents are significant issues for marine facilities,leading to considerable economic losses.Waterborne epoxy(EP)coating has been seen as one of the optimal options for corrosion pro...Corrosion activities and related accidents are significant issues for marine facilities,leading to considerable economic losses.Waterborne epoxy(EP)coating has been seen as one of the optimal options for corrosion protection due to its stable properties and eco-friendliness(0 g/L volatile organic compounds).Nevertheless,several intrinsic deficiencies require improvement,such as fragile mechanical properties and defects(macro and micro),resulting in the continuous deterioration of comprehensive coating performances.In this work,a novel nanocomposite coating with mechanical enhancement,intelligent self-reporting,and active protection is fabricated by integrating the functionalized and compatible graphene oxide/cerium based metal-organic framework multiscale structure(GO-CeMOF-P/M).Notably,the homogenous dispersion of GO-CeMOF-P/M and its chemical interaction with the polymer matrix effectively reduces the defects resulting from solution volatilizing and enhances the compactness,which boosts the tensile strength(32.1 MPa/8.5%)and dry adhesion force(5.8 MPa)of the coating.Additionally,the controllable responsiveness and release of multiscale nanocomposite within external environments endow intelligent active protection and self-reporting characteristics for the GO-CeMOF-P/M-EP coating,making it especially suitable for a variety of practical marine applications.Furthermore,following immersion of 80 d in the aggressive environment,Zf=0.01 Hz value of GO-CeMOF-P/M-EP coating is 1.2×10^(10)Ωcm^(2),which is 164.4 times larger than that of EP coating(7.3×10^(7)Ωcm^(2)),demonstrating remarkably strengthened anti-corrosion ability.Consequently,by offering an intriguing design strategy,the current work anticipates addressing the inherent deficiencies of EP coating and facilitating its practicality and feasibility in real sea environments.展开更多
Coatings of marine equipment inevitably suffer from physical or chemical damage in service,together with biofouling from microbial attachment,leading to a shorter service life of them.Herein,a multi-functional corrosi...Coatings of marine equipment inevitably suffer from physical or chemical damage in service,together with biofouling from microbial attachment,leading to a shorter service life of them.Herein,a multi-functional corrosion-resistant coating with efficient photothermal self-healing and anti-biofouling per-formance was designed by using CuO/g-C_(3)N_(4)(CuO/CN)S-scheme heterojunction filler in combination with polydimethylsiloxane(PDMS)as the coating matrix for achieving the effective protection of Q235 steel.The results of the electrochemical impedance spectroscopy(EIS)experiments indicate that the CuO/CN/PDMS composite coatings possessed excellent corrosion resistance,in which the impedance ra-dius of optimal CuO/CN-1/PDMS composite coating could still remain 3.49×10^(9)Ωcm^(2)after 60 d of immersion in seawater under sunlight irradiation.Meanwhile,the as-prepared CuO/CN/PDMS compos-ite coating not only can be rapidly heated up under the Xenon lamp illumination to achieve complete self-repair of scratches within 45 min,but also exhibited excellent antimicrobial effects in the antifouling experiments.This study opens a new avenue for the development of g-C_(3)N_(4)-based multifunctional coat-ings and provides guidance for the development of the next generation of intelligent protective coatings.展开更多
Magnesium potassium phosphate cement(MKPC)coatings exhibit potential for carbon steel protection but face challenges in practical application due to the preparation process and properties.This study develops flake gra...Magnesium potassium phosphate cement(MKPC)coatings exhibit potential for carbon steel protection but face challenges in practical application due to the preparation process and properties.This study develops flake graphite(FG)-modified MKPC coatings via spraying process,investigating the effects of FG size and dosage on phase composition,microstructure,mechanical properties,corrosion protection,and thermal conductivity.Results show that a low FG dosage(5 wt%)synergistically optimizes multifunctional performance.Compared to unmodified MKPC,FG2-1 exhibited exceptional impact resistance,associated with a 57%reduction in corrosion current density(icorr),a 356.3% increase in low-frequency impedance modulus(Z_(0.01 Hz))and a 37% increase in thermal conductivity.However,the coating with a high FG dosage(15 wt%)degraded performance due to defect accumulation and reduced crystallinity of KMgPO_(4)·6H_(2)O.This work advances the rational design of multifunctional inorganic coatings for extreme service environments requiring coupled corrosion protection and thermal management.展开更多
In this work,a versatile strategy of manipulating defective metal organic frameworks(MOFs)with the assistance of the steric hindrance effect was proposed and applied in coatings.The steric hindrance effect was utilize...In this work,a versatile strategy of manipulating defective metal organic frameworks(MOFs)with the assistance of the steric hindrance effect was proposed and applied in coatings.The steric hindrance effect was utilized to construct the defective MOFs with phosphate,gluconate and phytate as examples.The defective MOFs were synthesized in an aqueous solution at room temperature,having a promising future for industrial application.Tailoring specific defects in MOFs can make molecular chains of polymer penetrate into the internal skeleton and form an interlocking structure.The interlocking effect can enhance the mechanical performance of the coating,and the corrosion inhibition performance of anions can synergistically improve the corrosion resistance of the coating.The waterborne acrylic resin(WAR)embedded with phytate-modified MOF has the highest tensile strength of 23.9 MPa,four times higher than pure WAR.Anti-corrosion test results indicated that the corrosion inhibition efficiencies of composite coatings maintained around 97%after 2 months of immersion in seawater.The structure-property relations of defect-engineered MOFs and the anti-corrosion mechanisms were elaborated in detail by both experiments and molecular dynamics simulation.This strategy has excellent environmental friendliness,reduces the cost of MOF materials,and has broad application prospects.展开更多
Metal-based electromagnetic interference(EMI)shielding composites are essential for ensuring electromagnetic compatibility but are often compromised by susceptibility to corrosion,especially in harsh environments.Exis...Metal-based electromagnetic interference(EMI)shielding composites are essential for ensuring electromagnetic compatibility but are often compromised by susceptibility to corrosion,especially in harsh environments.Existing strategies to mitigate coupling corrosion typically involve physical barriers,which inevitably hinder conductivity.In this study,we introduce a novel interface doping approach to fabricate lightweight Graphite@PDA/Ag@Ag composites that simultaneously enhance EMI shielding and corrosion resistance.The PDA/Ag layer selectively regulates electrons with different migration directions and energies to migrate,increasing charge transfer resistance at Ag/graphite interfaces and ensuring conductivity through a tunneling effect.This design achieves an ultralow corrosion rate of 4.313×10–8µm/y(a billionth that of 316 L stainless steel)alongside superior EMI shielding effectiveness of 109 dB in the X-band at 1.5 mm thickness.Remarkably,the composite maintains over 90 dB shielding efficiency after 7 d in NaCl solutions across various pH levels.Furthermore,simulated corrosion under South China Sea conditions predicts a coating loss of less than 0.026µm over 7 years.This work presents a transformative approach to mitigating coupling corrosion in EMI shielding materials,offering a practical route to high-performance,corrosion-resistant composites without the need for a protective topcoat.展开更多
Copper materials have emerged as the preferred choice for marine heat exchangers owing to their excep-tional thermal conductivity.The enhancement of surface performance can be significantly achieved by engineering mic...Copper materials have emerged as the preferred choice for marine heat exchangers owing to their excep-tional thermal conductivity.The enhancement of surface performance can be significantly achieved by engineering micro-nano structures on the material’s surface,thereby attaining improved corrosion resis-tance and antibacterial properties in complex marine environments.In this study,we directly fabricated a copper nanopillar array structure on the substrate via template-assisted electrodeposition.Subsequently,passivation of the pillar-structured copper surface was achieved through a formate&dodecanethiol-assisted solvothermal process(Cu/FA-DT).The results indicate that the nanopillar structure effectively eliminates bacteria through physical rupture upon contact,leading to an 85.47%reduction in P.aerug-inosa adhesion compared to untreated samples after 72 h of immersion in seawater.Furthermore,cor-rosion resistance is significantly enhanced,with inhibition rates of approximately 95.27%and 90.50%in natural and P.aeruginosa containing seawater,respectively.Notably,the thermal conductivity of copper is well preserved,ensuring its functional integrity in marine heat exchange environments.After 7 days of immersion in natural and P.aeruginosa containing seawater,the thermal conductivity of Cu/FA-DT de-creased by only 15.41%and 2.78%,respectively,demonstrating superior thermal conductivity retention compared to untreated bare copper.This study provides valuable insights into the potential application of traditional copper in marine heat exchange environments.展开更多
Slippery liquid-infused porous surfaces(SLIPS)with exceptional liquid repellency and extremely low sliding angles demonstrate significant potential for applications in anti-corrosion,anti-fouling,and anti-scaling.Howe...Slippery liquid-infused porous surfaces(SLIPS)with exceptional liquid repellency and extremely low sliding angles demonstrate significant potential for applications in anti-corrosion,anti-fouling,and anti-scaling.However,the poor stability of the oil layer restricts its practical applications.Herein,a durable SLIPS coating with highly stable oil layer was developed by combining hierarchical porous structures with covalent interpenetrating networks and multiple interfacial interactions.The hierarchical porous structure was constructed via urea thermal decomposition with in situ hybridization of SiO_(2)and embedded carbon nanotubes(CNTs).Furthermore,the oil layer was chemically immobilized on the coating surface using methylenediphenyl diisocyanate(MDI)as a molecular bridge,leveraging interfacial covalent bonding andπ-OH interactions,which significantly enhanced its anti-corrosion properties,with an initial|Z|_(0.01 Hz)of1.22×10^(8)Ωcm^(2).Dynamic scaling experiments revealed a 96.47%improvement in scaling inhibition efficiency compared to conventional superhydrophobic coatings,showing its excellent anti-scaling properties.Owing to the durability and liquidity of oi layer,the prepared FEVE-SiO_(2)/CNTs@MDI SLIPS coating maintained outstanding slippery performance(water sliding angle<10°)even after 14 days of underwater immersion.Additionally,the coating also exhibited excellent thermal stability(120°C),remarkable shear resistance(5000 rpm),and ultraviolet resistance performance.Therefore,the prepared FEVE-SiO_(2)/CNTs@MDI SLIPS coating has broad practical application prospects in the field of industrial oilfield pipeline protection.展开更多
Combining conventional waterborne epoxy coatings(WEP)with specific functionalities is essential to increase their service life.However,designing multifunctional protective coatings with tunable interfaces to improve t...Combining conventional waterborne epoxy coatings(WEP)with specific functionalities is essential to increase their service life.However,designing multifunctional protective coatings with tunable interfaces to improve their corrosion and weather resistance remains challenging.In this study,based on intermolecular forces between quaternized lignosulfonate(QLS)and tertbutyl titanate,we prepared QLS-TiO_(2)nanocomposite with structural regularity and strong chemical bonding by a simple one-pot method.It was further used for doped modified WEP to prepare a high-performance QLS-TiO_(2)/WEP coating.The results showed that QLS-TiO_(2)can effectively scavenge radicals,absorb and reflect strong ultraviolet rays,and exhibit high dispersibility and interfacial compatibility in the epoxy matrix.Consequently,QLS-TiO_(2)/WEP coating demonstrated excellent weathering resistance,with the polymer chain segments within the coatings remaining intact after 240 h of accelerated aging test.Furthermore,QLS-TiO_(2)exhibited chemical stability and impressive anti-corrosion properties.Its incorporation into epoxy coatings effectively prolonged the corrosion pathway.Therefore,QLS-TiO_(2)/WEP demonstrated excellent anti-corrosion performance in high salt,acid,and alkali.Especially under acidic conditions,its|Z|10 mHzwas5.810×10^(7)Ωcm^(2),which improved three orders of magnitude compared with WEP(3.688×10~4Ωcm^(2)).This study innovates the design concept of high-performance biomass functional waterborne epoxy anti-corrosion coating and is conducive to the high-value utilization of biomass.展开更多
The effect of cerium dioxide(CeO_2)as an additive on the structure and properties of a melting type coating has been studied by means of microhardness measurement,scanning electron microscopy and thermal analysis. The...The effect of cerium dioxide(CeO_2)as an additive on the structure and properties of a melting type coating has been studied by means of microhardness measurement,scanning electron microscopy and thermal analysis. The results show that cerium dioxide can modify the microstructure and tribological properties of the coating. Model LIC-23 composite coating which contains CeO_2 performs well as a self-lubricating coating in hydrochloric acid solution.展开更多
Herein,3‑aminopropyltriethoxysilane(APTES)was used to modify F‑containing silica slag(SS)by simple grafting and served as a multifunctional barrier layer.The amino group(—NH2)in the amino‑modified SS(NH2‑SS)forms lig...Herein,3‑aminopropyltriethoxysilane(APTES)was used to modify F‑containing silica slag(SS)by simple grafting and served as a multifunctional barrier layer.The amino group(—NH2)in the amino‑modified SS(NH2‑SS)forms ligand bonds or hydrogen bonds with sulfur ions in lithium polysulfides(LiPSs),thus inhibiting the shuttle effect.Electrochemical analyses demonstrated that lithium‑sulfur(Li‑S)batteries employing the NH2‑SS interlayer exhibited discharge specific capacities of 1048 and 789 mAh·g^(-1) at 0.2C and 2C,respectively,and even at 4C,the initial discharge specific capacity remained at 590 mAh·g^(-1),outperforming the Li‑S battery with unmodified SS as the interlayer.展开更多
Chitosan(CTS)was grafted onto the surface of amino‑functionalized silver chloride silicon dioxide(AgCl@SiO_(2)‑NH_(2))cores to obtain AgCl@SiO_(2)/CTS hybrid nanoparticles.The as‑obtained AgCl@SiO_(2)/CTS nanoparticle...Chitosan(CTS)was grafted onto the surface of amino‑functionalized silver chloride silicon dioxide(AgCl@SiO_(2)‑NH_(2))cores to obtain AgCl@SiO_(2)/CTS hybrid nanoparticles.The as‑obtained AgCl@SiO_(2)/CTS nanoparticles were chlorinated by NaClO solution to get AgCl@SiO_(2)/CTS‑based chloramine nano‑hybrid materials,denoted as AgCl@SiO_(2)/CTS‑Cl.A transmission electron microscope was used to observe the morphology of the as‑prepared samples AgCl@SiO_(2)/CTS and AgCl@SiO_(2)/CTS‑Cl.At the same time,an X‑ray diffractometer and an infrared spectroscope were utilized to characterize their crystal and chemical structures.Besides,ζpotentials were measured to elucidate the surface modification of AgCl nanoparticles by—NH_(2),the antibacterial mechanism of AgCl@SiO_(2)/CTS‑Cl was investigated by scanning electron microscopy,and Escherichia coli(E.coli)and Staphylococcus aureus(S.aureus)were used as the to‑be‑tested strains to evaluate the antimicrobial activity of samples AgCl@SiO_(2)/CTS and AgCl@SiO_(2)/CTS‑Cl.Findings demonstrate that sample AgCl@SiO_(2)/CTS exhibits a chain‑like structure ascribed to the interaction between—NH_(2),and each AgCl@SiO_(2)/CTS hybrid nanoparticle contains several AgCl cores.In the meantime,sample AgCl@SiO_(2)/CTS‑Cl exhibits excellent antibacterial activity against E.coli and S.aureus,which is attributed to the synergistic antibacterial effect of Ag^(+)and Cl^(-).Sample AgCl@SiO_(2)/CTS‑Cl with a dosage of 640.00μg·mL^(-1) could completely kill the two kinds of tested bacteria in 12 h of incubation;it retains a high antibacterial efficiency even after 10 cycles of antibacterial tests.展开更多
Rechargeable Zn/Sn-air batteries have received considerable attention as promising energy storage devices.However,the electrochemical performance of these batteries is significantly constrained by the sluggish electro...Rechargeable Zn/Sn-air batteries have received considerable attention as promising energy storage devices.However,the electrochemical performance of these batteries is significantly constrained by the sluggish electrocatalytic reaction kinetics at the cathode.The integration of light energy into Zn/Sn-air batteries is a promising strategy for enhancing their performance.However,the photothermal and photoelectric effects generate heat in the battery under prolonged solar irradiation,leading to air cathode instability.This paper presents the first design and synthesis of Ni_(2)-1,5-diamino-4,8-dihydroxyanthraquinone(Ni_(2)DDA),an electronically conductiveπ-d conjugated metal-organic framework(MOF).Ni_(2)DDA exhibits both photoelectric and photothermal effects,with an optical band gap of~1.14 eV.Under illumination,Ni_(2)DDA achieves excellent oxygen evolution reaction performance(with an overpotential of 245 mV vs.reversible hydrogen electrode at 10 mA cm^(−2))and photothermal stability.These properties result from the synergy between the photoelectric and photothermal effects of Ni_(2)DDA.Upon integration into Zn/Sn-air batteries,Ni_(2)DDA ensures excellent cycling stability under light and exhibits remarkable performance in high-temperature environments up to 80℃.This study experimentally confirms the stable operation of photo-assisted Zn/Sn-air batteries under high-temperature conditions for the first time and provides novel insights into the application of electronically conductive MOFs in photoelectrocatalysis and photothermal catalysis.展开更多
Beam-tracking simulations have been extensively utilized in the study of collective beam instabilities in circular accelerators.Traditionally,many simulation codes have relied on central processing unit(CPU)-based met...Beam-tracking simulations have been extensively utilized in the study of collective beam instabilities in circular accelerators.Traditionally,many simulation codes have relied on central processing unit(CPU)-based methods,tracking on a single CPU core,or parallelizing the computation across multiple cores via the message passing interface(MPI).Although these approaches work well for single-bunch tracking,scaling them to multiple bunches significantly increases the computational load,which often necessitates the use of a dedicated multi-CPU cluster.To address this challenge,alternative methods leveraging General-Purpose computing on Graphics Processing Units(GPGPU)have been proposed,enabling tracking studies on a standalone desktop personal computer(PC).However,frequent CPU-GPU interactions,including data transfers and synchronization operations during tracking,can introduce communication overheads,potentially reducing the overall effectiveness of GPU-based computations.In this study,we propose a novel approach that eliminates this overhead by performing the entire tracking simulation process exclusively on the GPU,thereby enabling the simultaneous processing of all bunches and their macro-particles.Specifically,we introduce MBTRACK2-CUDA,a Compute Unified Device Architecture(CUDA)ported version of MBTRACK2,which facilitates efficient tracking of single-and multi-bunch collective effects by leveraging the full GPU-resident computation.展开更多
Fe_(3)Sn_(2),a ferromagnetic metal with a kagome lattice,serves as an ideal platform for exploring topological electronic states and Berry curvature due to its unique band structure.However,systematic reports on the t...Fe_(3)Sn_(2),a ferromagnetic metal with a kagome lattice,serves as an ideal platform for exploring topological electronic states and Berry curvature due to its unique band structure.However,systematic reports on the transport properties of Fe_(3)Sn_(2)nanosheets remain scarce.We present temperature-dependent transport property measurements of Fe_(3)Sn_(2)nanosheets synthesized via chemical vapor deposition on Si/SiO_(2)substrates.The samples exhibit a robust anomalous Hall effect from 40 K to 300 K,along with a magnetoresistance sign reversal at 40 K at high magnetic fields,indicating a spin reorientation from in-plane to out-of-plane.Notably,a sharp crossover in the dominant transport contribution from electrons to holes near 200 K is observed,accompanied by distinct anomalous Hall behaviors in the two regimes,indicating a temperature-induced Lifshitz transition within the multi-band system.This divergence is potentially linked to a topological reconstruction of the Fermi surface across the transition.Our findings highlight the tunability of topological transport in two-dimensional kagome magnets and provide new insights into the interplay between band topology,dimensionality and magnetic order.展开更多
[Objectives]To explore the control mode of farmland drainage pollutants and investigate the effects of ecological ditch and wetland on reducing farmland drainage pollutants in Hetao Irrigation District.[Methods]Based ...[Objectives]To explore the control mode of farmland drainage pollutants and investigate the effects of ecological ditch and wetland on reducing farmland drainage pollutants in Hetao Irrigation District.[Methods]Based on the demonstration construction project of the ecological ditch-constructed wetland system in the Hetao Irrigation District,an experimental study was conducted from July to September 2023 to investigate the interception and purification effects of ecological ditches,constructed wetlands,and the combined ecological ditch-constructed wetland system on farmland drainage pollutants.Key water quality parameters measured included total nitrogen(TN)concentration and total phosphorus(TP)concentration.[Results]Different treatment modes of ecological ditches and constructed wetlands have a certain removal effect on nitrogen and phosphorus pollutants in water bodies.The ecological ditches treated with Astragalus laxmannii,Melilotus officinalis,Medicago sativa,bio-ball substrate,and bio-sheet substrate showed reduction efficiencies for TN and TP of 21.09% and 23.84%,12.06% and 26.67%,20.08% and 34.15%,23.65% and 20.56%,and 19.92% and 25.83%,respectively.The emergent plant area showed reduction efficiencies of 24.28%for TN and 17.89%for TP,while the submerged plant area achieved a reduction efficiency of 10.21%for both TN and TP.Among the different treatment modes,the ecological ditch with M.sativa performed better in TP removal,whereas the bio-ball substrate treatment mode showed higher effectiveness in TN removal.In addition,the emergent plant area exhibited better TP removal performance,while the submerged plant area was more effective in TN removal.The combined system of ecological ditch and constructed wetland achieved removal rates of 37.55% for TN and 11.47% for TP.It effectively facilitates the step-by-step interception and adsorption purification of pollutants,thereby showing significant removal and purification effects on nitrogen and phosphorus contaminants.This contributes to mitigating agricultural non-point source pollution.[Conclusions]The combined ecological ditch-constructed wetland system serves dual functions of agricultural drainage and pollutant interception and purification.It reduces the pollution load of farmland drainage on receiving water bodies to some extent and mitigates agricultural non-point source pollution.Therefore,it is a relatively suitable technology for managing agricultural non-point source pollution in the Hetao Irrigation District.展开更多
The effect of adding hydroxycinnamic acids(caffeic acid,sinapic acid,p-coumaric acid and chlorogenic acid)in Cabernet Sauvignon dry red wine before and after fermentation was investigated,taking into account the color...The effect of adding hydroxycinnamic acids(caffeic acid,sinapic acid,p-coumaric acid and chlorogenic acid)in Cabernet Sauvignon dry red wine before and after fermentation was investigated,taking into account the color parameters,anthocyanin content,and overall polyphenol levels in the wine samples.The copigmentation effect of malvidin-3-Oglucoside and sinapic acid was further explored in model solution and through theoretical calculations.The results indicated that the addition of hydroxycinnamic acids significantly enhanced the wine's color with sinapic acid(before the fermentation)showing the most pronounced color protection effect.Compared to control samples,the addition of hydroxycinnamic acids resulted in a 36%increase in total phenolic content and a 28% increase in total anthocyanin content.Thermodynamic analysis revealed that the interaction between sinapic acid and malvidin-3-O-glucoside was spontaneous and exothermic.Theoretical studies identified hydrogen bonding(HB)and dispersion forces as the main primary stabilizing forces,with the carboxyl group of sinapic acid playing a critical role while the anthocyanin backbone also influenced the interaction.展开更多
Benzalkonium chloride(BAC)is widely employed as a broad-spectrum biocide and has emerged as a significant environmental pollutant.Polymyxin B(PB)serves as the last-line defense for the treatment of Gram-negative patho...Benzalkonium chloride(BAC)is widely employed as a broad-spectrum biocide and has emerged as a significant environmental pollutant.Polymyxin B(PB)serves as the last-line defense for the treatment of Gram-negative pathogens.Previous studies reported that BAC-adapted Pseudomonas aeruginosa increased the tolerance to PB.Herein,we present the novel finding that the combination of BAC and PB exhibited synergistic antibacterial effects against P.aeruginosa.Time-killing assay demonstrated a significant reduction in bacterial cell viability.Scanning electron microscopy,zeta potential analysis,hydrophobicity measurements,and fluorescence probe analyses collectively revealed severe disruption of the cell envelope and membrane potential induced by the combination of BAC and PB.Transcriptomic analysis revealed that the BAC-PB combination notably downreg-ulated the expression of genes involved in lipid A modification and cell envelope production,including phoPQ,pmrAB,bamABCDE,lptABCDEG,lolB,yidC,and murJ.Additionally,the combination group exhibited augmented production of reactive oxygen species and diminished ATP synthesis.The expression of the genes associated with substance metabolism and energy generation was significantly impeded.This study provides significant implica-tions for the interactions of biocides and antibiotics on Gram-negative pathogens,while also addressing antibiotic resistance and developing the external treatment strategy for Pseudomonas-infected wounds and burns.展开更多
Inflammatory bowel disease(IBD),which includes Crohn’s disease(CD)and ulcerative colitis(UC),is a chronic inflammatory condition affecting the gastrointestinal tract.The global incidence and prevalence of IBD continu...Inflammatory bowel disease(IBD),which includes Crohn’s disease(CD)and ulcerative colitis(UC),is a chronic inflammatory condition affecting the gastrointestinal tract.The global incidence and prevalence of IBD continue to increase.While multiple clinical treatments exist,conventional therapies frequently present limitations and adverse effects.Natural polysaccharides(PSs)have emerged as a significant focus of research interest due to their therapeutic potential and applications in functional foods and health products.This review synthesizes current understanding of IBD pathophysiology and the mechanisms by which natural PSs counter IBD,including their capacity to restore immune homeostasis and intestinal barrier function,modulate gut microbiota and metabolites,reduce oxidative stress,and address irregularities in autophagy and endoplasmic reticulum stress(ERS).The review examines the structure-activity relationships of PSs demonstrating anti-IBD effects and identifies promising therapeutic products.The discussion encompasses pharmacokinetics,safety evaluations,and clinical applications of these compounds.This comprehensive review establishes a theoretical foundation for developing natural PS-based therapeutic approaches for IBD management.展开更多
This article reviews the research advances in traditional Chinese medicine rhubarb and its compound formulations in the treatment of sepsis,with particular emphasis on elucidating their mechanisms of action and clinic...This article reviews the research advances in traditional Chinese medicine rhubarb and its compound formulations in the treatment of sepsis,with particular emphasis on elucidating their mechanisms of action and clinical application value.Research has demonstrated that rhubarb and its compound formulations exert therapeutic effects via multiple targets and mechanisms,including anti-inflammatory actions,protection of the intestinal barrier,modulation of immune balance,inhibition of oxidative stress,and regulation of associated signaling pathways.Clinically,rhubarb has shown distinct advantages in enhancing gastrointestinal function,mitigating systemic inflammatory responses,and reducing mortality rates among patients with sepsis.These findings provide a foundational reference for the integrated prevention and treatment of sepsis through the combined use of traditional Chinese and Western medicine.展开更多
AIM:To evaluate and compare alterations in the effective lens position(ELP)and refractive outcomes among three distinct intraocular lens(IOL)types.METHODS:Patients with cataracts were enrolled and allocated to 3 group...AIM:To evaluate and compare alterations in the effective lens position(ELP)and refractive outcomes among three distinct intraocular lens(IOL)types.METHODS:Patients with cataracts were enrolled and allocated to 3 groups:Group A(implanted with the SN6CWS),Group B(implanted with the MI60),and Group C(implanted with the Aspira-aA).ELP measurements were obtained with swept-source optical coherence tomography(SS-OCT)at 1d,1wk,1mo,and 3mo postoperatively.Subjective refraction assessments were conducted at 1wk,1mo,and 3mo following surgery.RESULTS:The study included 189 eyes of 150 cataract patients(66 males).There were 77 eyes in Group A,55 eyes in Group B,and 57 eyes in Group C.The root mean square of the ELP(ELPRMS)within the initial 3mo was significantly lower for Group A than for Groups B and C.Refractive changes within Group A were not significant across the time points of 1wk,1mo,and 3mo.Conversely,both Group B and Group C demonstrated statistically significant shifts toward hyperopia from 1wk to 3mo postsurgery.CONCLUSION:Among the three IOLs examined,the SN6CWS IOL showes the greatest stability during the first 3mo postoperatively.Between 1wk and 3mo after surgery,notable hyperopic shifts are evident in eyes implanted with the MI60 and Aspira-aA IOLs,whereas refractive outcomes remain relatively constant in eyes implanted with SN6CWS IOLs.展开更多
基金financially supported by the National Natural Science Foundation of China(Nos.52371088,52071347,and U20A20233)Guangdong Basic and Applied Basic Research Foundation(No.2023A1515240007)Shenzhen Science and Technology Program(No.KJZD20230923114819041).
文摘Corrosion activities and related accidents are significant issues for marine facilities,leading to considerable economic losses.Waterborne epoxy(EP)coating has been seen as one of the optimal options for corrosion protection due to its stable properties and eco-friendliness(0 g/L volatile organic compounds).Nevertheless,several intrinsic deficiencies require improvement,such as fragile mechanical properties and defects(macro and micro),resulting in the continuous deterioration of comprehensive coating performances.In this work,a novel nanocomposite coating with mechanical enhancement,intelligent self-reporting,and active protection is fabricated by integrating the functionalized and compatible graphene oxide/cerium based metal-organic framework multiscale structure(GO-CeMOF-P/M).Notably,the homogenous dispersion of GO-CeMOF-P/M and its chemical interaction with the polymer matrix effectively reduces the defects resulting from solution volatilizing and enhances the compactness,which boosts the tensile strength(32.1 MPa/8.5%)and dry adhesion force(5.8 MPa)of the coating.Additionally,the controllable responsiveness and release of multiscale nanocomposite within external environments endow intelligent active protection and self-reporting characteristics for the GO-CeMOF-P/M-EP coating,making it especially suitable for a variety of practical marine applications.Furthermore,following immersion of 80 d in the aggressive environment,Zf=0.01 Hz value of GO-CeMOF-P/M-EP coating is 1.2×10^(10)Ωcm^(2),which is 164.4 times larger than that of EP coating(7.3×10^(7)Ωcm^(2)),demonstrating remarkably strengthened anti-corrosion ability.Consequently,by offering an intriguing design strategy,the current work anticipates addressing the inherent deficiencies of EP coating and facilitating its practicality and feasibility in real sea environments.
基金supported by the National Natural Science Foundation of China(Nos.22006057 and 21906072)the China Postdoctoral Science Foundation(No.2023M743178)+2 种基金the Jiangsu Province Industry-University-Research Cooperation Project(No.BY20231482)the Open Fund of the Key Laboratory of Solar Cell electrode Materials in China Petroleum,Chemical Industry(No.2024A093)the Key Laboratory of Functional Inorganic Mate-rial Chemistry(Heilongjiang University),Ministry of Education and Postgraduate Research&Practice Innovation Program of Jiangsu Province(China)(No.SJCX24_2481).
文摘Coatings of marine equipment inevitably suffer from physical or chemical damage in service,together with biofouling from microbial attachment,leading to a shorter service life of them.Herein,a multi-functional corrosion-resistant coating with efficient photothermal self-healing and anti-biofouling per-formance was designed by using CuO/g-C_(3)N_(4)(CuO/CN)S-scheme heterojunction filler in combination with polydimethylsiloxane(PDMS)as the coating matrix for achieving the effective protection of Q235 steel.The results of the electrochemical impedance spectroscopy(EIS)experiments indicate that the CuO/CN/PDMS composite coatings possessed excellent corrosion resistance,in which the impedance ra-dius of optimal CuO/CN-1/PDMS composite coating could still remain 3.49×10^(9)Ωcm^(2)after 60 d of immersion in seawater under sunlight irradiation.Meanwhile,the as-prepared CuO/CN/PDMS compos-ite coating not only can be rapidly heated up under the Xenon lamp illumination to achieve complete self-repair of scratches within 45 min,but also exhibited excellent antimicrobial effects in the antifouling experiments.This study opens a new avenue for the development of g-C_(3)N_(4)-based multifunctional coat-ings and provides guidance for the development of the next generation of intelligent protective coatings.
基金National Key Research and Development Program of China(2024YFB3714804)National Natural Science Foundation of China(52171277)+1 种基金Baima Lake Laboratory Joint Funds of the Zhejiang Provincial Natural Science Foundation of China(LBMHZ24E020001)Shanxi-Zheda Institute of Advanced Materials and Chemical Engineering(2022SZ-TD006).
文摘Magnesium potassium phosphate cement(MKPC)coatings exhibit potential for carbon steel protection but face challenges in practical application due to the preparation process and properties.This study develops flake graphite(FG)-modified MKPC coatings via spraying process,investigating the effects of FG size and dosage on phase composition,microstructure,mechanical properties,corrosion protection,and thermal conductivity.Results show that a low FG dosage(5 wt%)synergistically optimizes multifunctional performance.Compared to unmodified MKPC,FG2-1 exhibited exceptional impact resistance,associated with a 57%reduction in corrosion current density(icorr),a 356.3% increase in low-frequency impedance modulus(Z_(0.01 Hz))and a 37% increase in thermal conductivity.However,the coating with a high FG dosage(15 wt%)degraded performance due to defect accumulation and reduced crystallinity of KMgPO_(4)·6H_(2)O.This work advances the rational design of multifunctional inorganic coatings for extreme service environments requiring coupled corrosion protection and thermal management.
基金financially supported by the National Natural Science Foundation of China(No.U2141251)Taishan Scholars Project of ShandongZhejiang Province High-Level Talent Supporting Program(No.2022R52001).
文摘In this work,a versatile strategy of manipulating defective metal organic frameworks(MOFs)with the assistance of the steric hindrance effect was proposed and applied in coatings.The steric hindrance effect was utilized to construct the defective MOFs with phosphate,gluconate and phytate as examples.The defective MOFs were synthesized in an aqueous solution at room temperature,having a promising future for industrial application.Tailoring specific defects in MOFs can make molecular chains of polymer penetrate into the internal skeleton and form an interlocking structure.The interlocking effect can enhance the mechanical performance of the coating,and the corrosion inhibition performance of anions can synergistically improve the corrosion resistance of the coating.The waterborne acrylic resin(WAR)embedded with phytate-modified MOF has the highest tensile strength of 23.9 MPa,four times higher than pure WAR.Anti-corrosion test results indicated that the corrosion inhibition efficiencies of composite coatings maintained around 97%after 2 months of immersion in seawater.The structure-property relations of defect-engineered MOFs and the anti-corrosion mechanisms were elaborated in detail by both experiments and molecular dynamics simulation.This strategy has excellent environmental friendliness,reduces the cost of MOF materials,and has broad application prospects.
基金supported by the National Science and Technology Major Project(No.J2019-VI-0015-013)Innovative Talent Promotion Program-Youth Science and Technology Emerging Project(No.2021KJXX-101)+5 种基金Science Fund for Distinguished Young Scholars of Shannxi Province(No.2023-JC-JQ-35)Fundamental Research Project of National Defense(No.2021-JCJQ-ZD-046-00)Northwestern Polytechnical University College Student Innovation and Entrepreneurship Training Program(No.S202310699574)National Natural Science Foundation of China(No.52302367)“Fundamental Research Funds for the Central Universities”(No.G2023KY05101)Special thanks to Dr.Minghui Fang(School of Materials Science and Engineering,Northwestern Polytechnical Uni-versity)for illustration production.
文摘Metal-based electromagnetic interference(EMI)shielding composites are essential for ensuring electromagnetic compatibility but are often compromised by susceptibility to corrosion,especially in harsh environments.Existing strategies to mitigate coupling corrosion typically involve physical barriers,which inevitably hinder conductivity.In this study,we introduce a novel interface doping approach to fabricate lightweight Graphite@PDA/Ag@Ag composites that simultaneously enhance EMI shielding and corrosion resistance.The PDA/Ag layer selectively regulates electrons with different migration directions and energies to migrate,increasing charge transfer resistance at Ag/graphite interfaces and ensuring conductivity through a tunneling effect.This design achieves an ultralow corrosion rate of 4.313×10–8µm/y(a billionth that of 316 L stainless steel)alongside superior EMI shielding effectiveness of 109 dB in the X-band at 1.5 mm thickness.Remarkably,the composite maintains over 90 dB shielding efficiency after 7 d in NaCl solutions across various pH levels.Furthermore,simulated corrosion under South China Sea conditions predicts a coating loss of less than 0.026µm over 7 years.This work presents a transformative approach to mitigating coupling corrosion in EMI shielding materials,offering a practical route to high-performance,corrosion-resistant composites without the need for a protective topcoat.
基金financially supported by the National Natural Science Foundation of China(Nos.42276212,42176043,and U2106206)the Shandong University Future Plan for Young Scholars.We thank Sen Wang,Haiyan Yu,and Xiaomin Zhao from the State Key Laboratory of Microbial Technology,Shandong University for the assistance in the microimaging of SEM analysis.
文摘Copper materials have emerged as the preferred choice for marine heat exchangers owing to their excep-tional thermal conductivity.The enhancement of surface performance can be significantly achieved by engineering micro-nano structures on the material’s surface,thereby attaining improved corrosion resis-tance and antibacterial properties in complex marine environments.In this study,we directly fabricated a copper nanopillar array structure on the substrate via template-assisted electrodeposition.Subsequently,passivation of the pillar-structured copper surface was achieved through a formate&dodecanethiol-assisted solvothermal process(Cu/FA-DT).The results indicate that the nanopillar structure effectively eliminates bacteria through physical rupture upon contact,leading to an 85.47%reduction in P.aerug-inosa adhesion compared to untreated samples after 72 h of immersion in seawater.Furthermore,cor-rosion resistance is significantly enhanced,with inhibition rates of approximately 95.27%and 90.50%in natural and P.aeruginosa containing seawater,respectively.Notably,the thermal conductivity of copper is well preserved,ensuring its functional integrity in marine heat exchange environments.After 7 days of immersion in natural and P.aeruginosa containing seawater,the thermal conductivity of Cu/FA-DT de-creased by only 15.41%and 2.78%,respectively,demonstrating superior thermal conductivity retention compared to untreated bare copper.This study provides valuable insights into the potential application of traditional copper in marine heat exchange environments.
基金financially supported by the National Natural Science Foundation of China(No.52203136)Heilongjiang Provincial Natural Science Foundation for Excellent Youth Fund(No.YQ2024E007)+4 种基金Natural Science Foundation of Heilongjiang Province(No.LH2022E015)the China Postdoctoral Science Foundation(No.2024MD753912)Heilongjiang Postdoctoral Fund(No.LBH-Z24107)Northeast Petroleum University Cultivation Foundation for‘National fund’(No.2023GPL-04)Northeast Petroleum University Scientic Research Foundation for Advanced Talents(Nos.2021KQ05,2019KQ85)
文摘Slippery liquid-infused porous surfaces(SLIPS)with exceptional liquid repellency and extremely low sliding angles demonstrate significant potential for applications in anti-corrosion,anti-fouling,and anti-scaling.However,the poor stability of the oil layer restricts its practical applications.Herein,a durable SLIPS coating with highly stable oil layer was developed by combining hierarchical porous structures with covalent interpenetrating networks and multiple interfacial interactions.The hierarchical porous structure was constructed via urea thermal decomposition with in situ hybridization of SiO_(2)and embedded carbon nanotubes(CNTs).Furthermore,the oil layer was chemically immobilized on the coating surface using methylenediphenyl diisocyanate(MDI)as a molecular bridge,leveraging interfacial covalent bonding andπ-OH interactions,which significantly enhanced its anti-corrosion properties,with an initial|Z|_(0.01 Hz)of1.22×10^(8)Ωcm^(2).Dynamic scaling experiments revealed a 96.47%improvement in scaling inhibition efficiency compared to conventional superhydrophobic coatings,showing its excellent anti-scaling properties.Owing to the durability and liquidity of oi layer,the prepared FEVE-SiO_(2)/CNTs@MDI SLIPS coating maintained outstanding slippery performance(water sliding angle<10°)even after 14 days of underwater immersion.Additionally,the coating also exhibited excellent thermal stability(120°C),remarkable shear resistance(5000 rpm),and ultraviolet resistance performance.Therefore,the prepared FEVE-SiO_(2)/CNTs@MDI SLIPS coating has broad practical application prospects in the field of industrial oilfield pipeline protection.
基金financially supported by the National Natural Science Foundation of China(No.22278092)the Young Talent Support Project of Guangzhou Association for Science and Technology(No.QT2024-004)+2 种基金the Science and Technology Research Project of Guangzhou(Nos.2023A03J0034,2023A04J0077,202102020467 and 2023A03J0064)the Key Discipline of Materials Science and Engineering,Bureau of Education of Guangzhou(No.202255464)the National College Student Innovation Training Program of Guangzhou University(No.202411078020)
文摘Combining conventional waterborne epoxy coatings(WEP)with specific functionalities is essential to increase their service life.However,designing multifunctional protective coatings with tunable interfaces to improve their corrosion and weather resistance remains challenging.In this study,based on intermolecular forces between quaternized lignosulfonate(QLS)and tertbutyl titanate,we prepared QLS-TiO_(2)nanocomposite with structural regularity and strong chemical bonding by a simple one-pot method.It was further used for doped modified WEP to prepare a high-performance QLS-TiO_(2)/WEP coating.The results showed that QLS-TiO_(2)can effectively scavenge radicals,absorb and reflect strong ultraviolet rays,and exhibit high dispersibility and interfacial compatibility in the epoxy matrix.Consequently,QLS-TiO_(2)/WEP coating demonstrated excellent weathering resistance,with the polymer chain segments within the coatings remaining intact after 240 h of accelerated aging test.Furthermore,QLS-TiO_(2)exhibited chemical stability and impressive anti-corrosion properties.Its incorporation into epoxy coatings effectively prolonged the corrosion pathway.Therefore,QLS-TiO_(2)/WEP demonstrated excellent anti-corrosion performance in high salt,acid,and alkali.Especially under acidic conditions,its|Z|10 mHzwas5.810×10^(7)Ωcm^(2),which improved three orders of magnitude compared with WEP(3.688×10~4Ωcm^(2)).This study innovates the design concept of high-performance biomass functional waterborne epoxy anti-corrosion coating and is conducive to the high-value utilization of biomass.
基金This is supported by the Youth Research Fund of Chinese Academy of Sciences
文摘The effect of cerium dioxide(CeO_2)as an additive on the structure and properties of a melting type coating has been studied by means of microhardness measurement,scanning electron microscopy and thermal analysis. The results show that cerium dioxide can modify the microstructure and tribological properties of the coating. Model LIC-23 composite coating which contains CeO_2 performs well as a self-lubricating coating in hydrochloric acid solution.
文摘Herein,3‑aminopropyltriethoxysilane(APTES)was used to modify F‑containing silica slag(SS)by simple grafting and served as a multifunctional barrier layer.The amino group(—NH2)in the amino‑modified SS(NH2‑SS)forms ligand bonds or hydrogen bonds with sulfur ions in lithium polysulfides(LiPSs),thus inhibiting the shuttle effect.Electrochemical analyses demonstrated that lithium‑sulfur(Li‑S)batteries employing the NH2‑SS interlayer exhibited discharge specific capacities of 1048 and 789 mAh·g^(-1) at 0.2C and 2C,respectively,and even at 4C,the initial discharge specific capacity remained at 590 mAh·g^(-1),outperforming the Li‑S battery with unmodified SS as the interlayer.
文摘Chitosan(CTS)was grafted onto the surface of amino‑functionalized silver chloride silicon dioxide(AgCl@SiO_(2)‑NH_(2))cores to obtain AgCl@SiO_(2)/CTS hybrid nanoparticles.The as‑obtained AgCl@SiO_(2)/CTS nanoparticles were chlorinated by NaClO solution to get AgCl@SiO_(2)/CTS‑based chloramine nano‑hybrid materials,denoted as AgCl@SiO_(2)/CTS‑Cl.A transmission electron microscope was used to observe the morphology of the as‑prepared samples AgCl@SiO_(2)/CTS and AgCl@SiO_(2)/CTS‑Cl.At the same time,an X‑ray diffractometer and an infrared spectroscope were utilized to characterize their crystal and chemical structures.Besides,ζpotentials were measured to elucidate the surface modification of AgCl nanoparticles by—NH_(2),the antibacterial mechanism of AgCl@SiO_(2)/CTS‑Cl was investigated by scanning electron microscopy,and Escherichia coli(E.coli)and Staphylococcus aureus(S.aureus)were used as the to‑be‑tested strains to evaluate the antimicrobial activity of samples AgCl@SiO_(2)/CTS and AgCl@SiO_(2)/CTS‑Cl.Findings demonstrate that sample AgCl@SiO_(2)/CTS exhibits a chain‑like structure ascribed to the interaction between—NH_(2),and each AgCl@SiO_(2)/CTS hybrid nanoparticle contains several AgCl cores.In the meantime,sample AgCl@SiO_(2)/CTS‑Cl exhibits excellent antibacterial activity against E.coli and S.aureus,which is attributed to the synergistic antibacterial effect of Ag^(+)and Cl^(-).Sample AgCl@SiO_(2)/CTS‑Cl with a dosage of 640.00μg·mL^(-1) could completely kill the two kinds of tested bacteria in 12 h of incubation;it retains a high antibacterial efficiency even after 10 cycles of antibacterial tests.
基金supported by the National Natural Science Foundation of China(No.62464010)Spring City Plan-Special Program for Young Talents(K202005007)+2 种基金Yunnan Talents Support Plan for Young Talents(XDYC-QNRC-2022-0482)Yunnan Local Colleges Applied Basic Research Projects(202101BA070001-138)Frontier Research Team of Kunming University 2023.
文摘Rechargeable Zn/Sn-air batteries have received considerable attention as promising energy storage devices.However,the electrochemical performance of these batteries is significantly constrained by the sluggish electrocatalytic reaction kinetics at the cathode.The integration of light energy into Zn/Sn-air batteries is a promising strategy for enhancing their performance.However,the photothermal and photoelectric effects generate heat in the battery under prolonged solar irradiation,leading to air cathode instability.This paper presents the first design and synthesis of Ni_(2)-1,5-diamino-4,8-dihydroxyanthraquinone(Ni_(2)DDA),an electronically conductiveπ-d conjugated metal-organic framework(MOF).Ni_(2)DDA exhibits both photoelectric and photothermal effects,with an optical band gap of~1.14 eV.Under illumination,Ni_(2)DDA achieves excellent oxygen evolution reaction performance(with an overpotential of 245 mV vs.reversible hydrogen electrode at 10 mA cm^(−2))and photothermal stability.These properties result from the synergy between the photoelectric and photothermal effects of Ni_(2)DDA.Upon integration into Zn/Sn-air batteries,Ni_(2)DDA ensures excellent cycling stability under light and exhibits remarkable performance in high-temperature environments up to 80℃.This study experimentally confirms the stable operation of photo-assisted Zn/Sn-air batteries under high-temperature conditions for the first time and provides novel insights into the application of electronically conductive MOFs in photoelectrocatalysis and photothermal catalysis.
基金supported by the National Research Foundation of Korea(NRF)funded by the Ministry of Science and ICT(MSIT)(No.RS-2022-00143178)the Ministry of Education(MOE)(Nos.2022R1A6A3A13053896 and 2022R1F1A1074616),Republic of Korea.
文摘Beam-tracking simulations have been extensively utilized in the study of collective beam instabilities in circular accelerators.Traditionally,many simulation codes have relied on central processing unit(CPU)-based methods,tracking on a single CPU core,or parallelizing the computation across multiple cores via the message passing interface(MPI).Although these approaches work well for single-bunch tracking,scaling them to multiple bunches significantly increases the computational load,which often necessitates the use of a dedicated multi-CPU cluster.To address this challenge,alternative methods leveraging General-Purpose computing on Graphics Processing Units(GPGPU)have been proposed,enabling tracking studies on a standalone desktop personal computer(PC).However,frequent CPU-GPU interactions,including data transfers and synchronization operations during tracking,can introduce communication overheads,potentially reducing the overall effectiveness of GPU-based computations.In this study,we propose a novel approach that eliminates this overhead by performing the entire tracking simulation process exclusively on the GPU,thereby enabling the simultaneous processing of all bunches and their macro-particles.Specifically,we introduce MBTRACK2-CUDA,a Compute Unified Device Architecture(CUDA)ported version of MBTRACK2,which facilitates efficient tracking of single-and multi-bunch collective effects by leveraging the full GPU-resident computation.
基金Project supported by the National Key Research and Development Program of China(Grant Nos.2022YFA1403503,2022YFA1602802,2023YFA1607400,and 2024YFA1613200)Beijing Natural Science Foundation(Grant No.JQ23022)supported by the Synergetic Extreme Condition User Facility and the Innovation Program for Quantum Science and Technology(Grant No.2021ZD0302600)。
文摘Fe_(3)Sn_(2),a ferromagnetic metal with a kagome lattice,serves as an ideal platform for exploring topological electronic states and Berry curvature due to its unique band structure.However,systematic reports on the transport properties of Fe_(3)Sn_(2)nanosheets remain scarce.We present temperature-dependent transport property measurements of Fe_(3)Sn_(2)nanosheets synthesized via chemical vapor deposition on Si/SiO_(2)substrates.The samples exhibit a robust anomalous Hall effect from 40 K to 300 K,along with a magnetoresistance sign reversal at 40 K at high magnetic fields,indicating a spin reorientation from in-plane to out-of-plane.Notably,a sharp crossover in the dominant transport contribution from electrons to holes near 200 K is observed,accompanied by distinct anomalous Hall behaviors in the two regimes,indicating a temperature-induced Lifshitz transition within the multi-band system.This divergence is potentially linked to a topological reconstruction of the Fermi surface across the transition.Our findings highlight the tunability of topological transport in two-dimensional kagome magnets and provide new insights into the interplay between band topology,dimensionality and magnetic order.
基金Supported by Special Fund Project for the Transformation of Scientific and Technological Achievements in Inner Mongolia Autonomous Region(2021CG0013)Bayannur City Science and Technology Plan Project(K202014)+1 种基金Inner Mongolia Autonomous Region Science and Technology Plan Project(2022YFHH0088)Research Special Project of the Education Department of Inner Mongolia Autonomous Region(STAQZX202320).
文摘[Objectives]To explore the control mode of farmland drainage pollutants and investigate the effects of ecological ditch and wetland on reducing farmland drainage pollutants in Hetao Irrigation District.[Methods]Based on the demonstration construction project of the ecological ditch-constructed wetland system in the Hetao Irrigation District,an experimental study was conducted from July to September 2023 to investigate the interception and purification effects of ecological ditches,constructed wetlands,and the combined ecological ditch-constructed wetland system on farmland drainage pollutants.Key water quality parameters measured included total nitrogen(TN)concentration and total phosphorus(TP)concentration.[Results]Different treatment modes of ecological ditches and constructed wetlands have a certain removal effect on nitrogen and phosphorus pollutants in water bodies.The ecological ditches treated with Astragalus laxmannii,Melilotus officinalis,Medicago sativa,bio-ball substrate,and bio-sheet substrate showed reduction efficiencies for TN and TP of 21.09% and 23.84%,12.06% and 26.67%,20.08% and 34.15%,23.65% and 20.56%,and 19.92% and 25.83%,respectively.The emergent plant area showed reduction efficiencies of 24.28%for TN and 17.89%for TP,while the submerged plant area achieved a reduction efficiency of 10.21%for both TN and TP.Among the different treatment modes,the ecological ditch with M.sativa performed better in TP removal,whereas the bio-ball substrate treatment mode showed higher effectiveness in TN removal.In addition,the emergent plant area exhibited better TP removal performance,while the submerged plant area was more effective in TN removal.The combined system of ecological ditch and constructed wetland achieved removal rates of 37.55% for TN and 11.47% for TP.It effectively facilitates the step-by-step interception and adsorption purification of pollutants,thereby showing significant removal and purification effects on nitrogen and phosphorus contaminants.This contributes to mitigating agricultural non-point source pollution.[Conclusions]The combined ecological ditch-constructed wetland system serves dual functions of agricultural drainage and pollutant interception and purification.It reduces the pollution load of farmland drainage on receiving water bodies to some extent and mitigates agricultural non-point source pollution.Therefore,it is a relatively suitable technology for managing agricultural non-point source pollution in the Hetao Irrigation District.
基金supported by the Key R&D Program of Shaanxi Province,China(2024NC-YBXM-146)the Xi’an Agricultural Technology Research and Development Project,China(24NYGG0048)+1 种基金the Key R&D Program of Xianyang,China(L2024-ZDYF-ZDYF-NY-0028)the National Foreign Expert Project of China(G2023172002L)。
文摘The effect of adding hydroxycinnamic acids(caffeic acid,sinapic acid,p-coumaric acid and chlorogenic acid)in Cabernet Sauvignon dry red wine before and after fermentation was investigated,taking into account the color parameters,anthocyanin content,and overall polyphenol levels in the wine samples.The copigmentation effect of malvidin-3-Oglucoside and sinapic acid was further explored in model solution and through theoretical calculations.The results indicated that the addition of hydroxycinnamic acids significantly enhanced the wine's color with sinapic acid(before the fermentation)showing the most pronounced color protection effect.Compared to control samples,the addition of hydroxycinnamic acids resulted in a 36%increase in total phenolic content and a 28% increase in total anthocyanin content.Thermodynamic analysis revealed that the interaction between sinapic acid and malvidin-3-O-glucoside was spontaneous and exothermic.Theoretical studies identified hydrogen bonding(HB)and dispersion forces as the main primary stabilizing forces,with the carboxyl group of sinapic acid playing a critical role while the anthocyanin backbone also influenced the interaction.
基金supported by the National Natural Science Foundation of China(No.32170121).
文摘Benzalkonium chloride(BAC)is widely employed as a broad-spectrum biocide and has emerged as a significant environmental pollutant.Polymyxin B(PB)serves as the last-line defense for the treatment of Gram-negative pathogens.Previous studies reported that BAC-adapted Pseudomonas aeruginosa increased the tolerance to PB.Herein,we present the novel finding that the combination of BAC and PB exhibited synergistic antibacterial effects against P.aeruginosa.Time-killing assay demonstrated a significant reduction in bacterial cell viability.Scanning electron microscopy,zeta potential analysis,hydrophobicity measurements,and fluorescence probe analyses collectively revealed severe disruption of the cell envelope and membrane potential induced by the combination of BAC and PB.Transcriptomic analysis revealed that the BAC-PB combination notably downreg-ulated the expression of genes involved in lipid A modification and cell envelope production,including phoPQ,pmrAB,bamABCDE,lptABCDEG,lolB,yidC,and murJ.Additionally,the combination group exhibited augmented production of reactive oxygen species and diminished ATP synthesis.The expression of the genes associated with substance metabolism and energy generation was significantly impeded.This study provides significant implica-tions for the interactions of biocides and antibiotics on Gram-negative pathogens,while also addressing antibiotic resistance and developing the external treatment strategy for Pseudomonas-infected wounds and burns.
基金supported by the National Natural Science Foundation of China(Nos.82003977,82274134 and 82274139)the National Key Research and Development Plan(No.2017YFC1702200)+1 种基金the Key Research and Development Program of Zhejiang Province(No.2020C04020)the Science and Technology Program of Zhejiang Province(No.2025C02183).
文摘Inflammatory bowel disease(IBD),which includes Crohn’s disease(CD)and ulcerative colitis(UC),is a chronic inflammatory condition affecting the gastrointestinal tract.The global incidence and prevalence of IBD continue to increase.While multiple clinical treatments exist,conventional therapies frequently present limitations and adverse effects.Natural polysaccharides(PSs)have emerged as a significant focus of research interest due to their therapeutic potential and applications in functional foods and health products.This review synthesizes current understanding of IBD pathophysiology and the mechanisms by which natural PSs counter IBD,including their capacity to restore immune homeostasis and intestinal barrier function,modulate gut microbiota and metabolites,reduce oxidative stress,and address irregularities in autophagy and endoplasmic reticulum stress(ERS).The review examines the structure-activity relationships of PSs demonstrating anti-IBD effects and identifies promising therapeutic products.The discussion encompasses pharmacokinetics,safety evaluations,and clinical applications of these compounds.This comprehensive review establishes a theoretical foundation for developing natural PS-based therapeutic approaches for IBD management.
基金Supported by National Natural Science Foundation of China(82374346)Double Hundred Outstanding Young and Middle-aged Medical and Health Talents of Wuxi City(BJ2023071)Scientific Research Project of Wuxi Municipal Health Commission(Q202358).
文摘This article reviews the research advances in traditional Chinese medicine rhubarb and its compound formulations in the treatment of sepsis,with particular emphasis on elucidating their mechanisms of action and clinical application value.Research has demonstrated that rhubarb and its compound formulations exert therapeutic effects via multiple targets and mechanisms,including anti-inflammatory actions,protection of the intestinal barrier,modulation of immune balance,inhibition of oxidative stress,and regulation of associated signaling pathways.Clinically,rhubarb has shown distinct advantages in enhancing gastrointestinal function,mitigating systemic inflammatory responses,and reducing mortality rates among patients with sepsis.These findings provide a foundational reference for the integrated prevention and treatment of sepsis through the combined use of traditional Chinese and Western medicine.
基金Supported by the Zhejiang Medical Health Science and Technology Project(No.2021KY217)the Basic Public Welfare Research Project of Wenzhou Municipal Science and Technology Bureau(No.2024Y1221).
文摘AIM:To evaluate and compare alterations in the effective lens position(ELP)and refractive outcomes among three distinct intraocular lens(IOL)types.METHODS:Patients with cataracts were enrolled and allocated to 3 groups:Group A(implanted with the SN6CWS),Group B(implanted with the MI60),and Group C(implanted with the Aspira-aA).ELP measurements were obtained with swept-source optical coherence tomography(SS-OCT)at 1d,1wk,1mo,and 3mo postoperatively.Subjective refraction assessments were conducted at 1wk,1mo,and 3mo following surgery.RESULTS:The study included 189 eyes of 150 cataract patients(66 males).There were 77 eyes in Group A,55 eyes in Group B,and 57 eyes in Group C.The root mean square of the ELP(ELPRMS)within the initial 3mo was significantly lower for Group A than for Groups B and C.Refractive changes within Group A were not significant across the time points of 1wk,1mo,and 3mo.Conversely,both Group B and Group C demonstrated statistically significant shifts toward hyperopia from 1wk to 3mo postsurgery.CONCLUSION:Among the three IOLs examined,the SN6CWS IOL showes the greatest stability during the first 3mo postoperatively.Between 1wk and 3mo after surgery,notable hyperopic shifts are evident in eyes implanted with the MI60 and Aspira-aA IOLs,whereas refractive outcomes remain relatively constant in eyes implanted with SN6CWS IOLs.
