The term "mélange" has several definitions due to the origin, tectonic and petrographical features. The geotechnical engineering behaviors of mélanges are either dominated by different kinds of int...The term "mélange" has several definitions due to the origin, tectonic and petrographical features. The geotechnical engineering behaviors of mélanges are either dominated by different kinds of intact rock blocks or matrix material. Landslides were encountered within the serpentinite matrix of Ankara Mélange, which is a typical bimrock mass. The residual sections of the extremely altered serpentinites are sandy soils. Such soils undergo rapid change of saturation, leading to shear strength reduction. Undisturbed and disturbed samples were obtained from the outcrops for shear box tests. Geochemical and petrographical composition of the serpentinites were determined by XRF(X Ray Fluorescence), XRD(X-ray diffraction) and thin section inspections, in order to outline the alteration process. Based on field observations, physically decomposed core stones exist beneath 40-120 cm thick residual green and grey-dark grey residual sandy soil. Physical and mechanical properties of the soils were tested with particular emphasis on residual shear strength parameters. Disturbed samples were remolded by standard compaction. The field work was completed during both rainy and summer seasons. Disturbed samples were prepared using phase diagrams in order to attain varying saturation degree. Two distinct sandy soil groups were determined through classification tests. The volumetric compression and/or expansion of the loose and dense samples were also considered based on the angle of dilatancy. A series of consolidated and drained shear box tests were conducted with ascending degree of saturation. The reduction of effective apparent cohesion, internal friction angle and dilatancy angle were determined to obtain a threshold of the degree of saturation. All the sand samples had zero residual internal friction angle and/or apparent cohesion after reaching 70% degree of saturation.展开更多
The airborne ragweed pollen spectrum was investigated in the air of Ankara, Turkey for aperiod of ten years (1990-1999) using a Burkard seven-day volumetric recording trap. In our study period,long distance transporte...The airborne ragweed pollen spectrum was investigated in the air of Ankara, Turkey for aperiod of ten years (1990-1999) using a Burkard seven-day volumetric recording trap. In our study period,long distance transported Ambrosia pollen has been registered. Daily pollen levels varied from low to highin Burge抯 system. In last three years, the pollen concentration of Ambrosia showed a clear increasingtendency. Our results prove that ragweed pollen may be an important threat for ragweed sensitive patientsin Ankara city in near future.展开更多
Vectored vaccines based on highly attenuated modified vaccinia Ankara(MVA) are reported to be immunogenic, tolerant to pre-existing immunity, and able to accommodate and stably maintain very large transgenes. MVA is u...Vectored vaccines based on highly attenuated modified vaccinia Ankara(MVA) are reported to be immunogenic, tolerant to pre-existing immunity, and able to accommodate and stably maintain very large transgenes. MVA is usually produced on primary chicken embryo fibroblasts, but production processes based on continuous cell lines emerge as increasingly robust and cost-effective alternatives. An isolate of a hitherto undescribed genotype was recovered by passage of a nonplaque-purified preparation of MVA in a continuous anatine suspension cell line(CR.pIX) in chemically defined medium.The novel isolate(MVA-CR19) replicated to higher infectious titers in the extracellular volume of suspension cultures and induced fewer syncytia in adherent cultures. We now extend previous studies with the investigation of the point mutations in structural genes of MVA-CR19 and describe an additional point mutation in a regulatory gene. We furthermore map and discuss an extensive rearrangement of the left telomer of MVA-CR19 that appears to have occurred by duplication of the right telomer. This event caused deletions and duplications of genes that may modulate immunologic properties of MVACR19 as a vaccine vector. Our characterizations also highlight the exceptional genetic stability of plaque-purified MVA:although the phenotype of MVA-CR19 appears to be advantageous for replication, we found that all genetic markers that differentiate wildtype and MVA-CR19 are stably maintained in passages of recombinant viruses based on either wildtype or MVA-CR.展开更多
The Museum of Anatolian Civilizations in Ankara in Turkey exhibits a glass paste phalera,which seems so far to have largely escaped scholarly attention,being illustrated only in 1990 and given a brief mention in 2017....The Museum of Anatolian Civilizations in Ankara in Turkey exhibits a glass paste phalera,which seems so far to have largely escaped scholarly attention,being illustrated only in 1990 and given a brief mention in 2017.It is circular with smooth edges which depicts a bust probably of Emperor Claudius with his three children.This glass phalera stands out among the numerous militaria in the Museum of Anatolian Civilizations in Ankara,which so far has not found adequate treatment.Typologically,it fits without difficulty into a series produced in the year AD 43 or shortly after that date.展开更多
In today＇s complex web of relations due to the end of the confrontation between the East and West, nuclear materials, technologies, know-how, and scientists have been diffused to states and non-state actors that act ...In today＇s complex web of relations due to the end of the confrontation between the East and West, nuclear materials, technologies, know-how, and scientists have been diffused to states and non-state actors that act irrationally most of the time. The precedent example of nuclear North Korea has given rise to new concerns like whether the low levels of military casualties stemming from nuclear or near-nuclear capable countries will damage the credibility of US/North Atlantic Treaty Organization （NATO） extended deterrence. The ambiguity about how the future of the Iranian Geneva interim agreement will be finalized certainly feeds such kinds of concerns among Tehran＇s neighbors. Till now, both Turkey and South Korea have directly felt and lived through similar kinds of threats. It is true that, during the Cold War years, these two countries have enjoyed the benefit of American assured nuclear security guarantee. However, the current US/NATO extended deterrence due to the mentioned newly arising threats of our times has fallen short of stopping the skirmishes that are occurring at low levels of confrontation. That is why this paper will try to analyze and compare South Korean and Turkish cases so as to comprehend whether there is a necessity to re-think extended deterrence mechanisms that are differently dispatched to meet Ankara＇s and Seoul＇s peculiar security needs.展开更多
基金supported by the Scientific Project Branch of Ankara University (Project no:13B4343004)
文摘The term "mélange" has several definitions due to the origin, tectonic and petrographical features. The geotechnical engineering behaviors of mélanges are either dominated by different kinds of intact rock blocks or matrix material. Landslides were encountered within the serpentinite matrix of Ankara Mélange, which is a typical bimrock mass. The residual sections of the extremely altered serpentinites are sandy soils. Such soils undergo rapid change of saturation, leading to shear strength reduction. Undisturbed and disturbed samples were obtained from the outcrops for shear box tests. Geochemical and petrographical composition of the serpentinites were determined by XRF(X Ray Fluorescence), XRD(X-ray diffraction) and thin section inspections, in order to outline the alteration process. Based on field observations, physically decomposed core stones exist beneath 40-120 cm thick residual green and grey-dark grey residual sandy soil. Physical and mechanical properties of the soils were tested with particular emphasis on residual shear strength parameters. Disturbed samples were remolded by standard compaction. The field work was completed during both rainy and summer seasons. Disturbed samples were prepared using phase diagrams in order to attain varying saturation degree. Two distinct sandy soil groups were determined through classification tests. The volumetric compression and/or expansion of the loose and dense samples were also considered based on the angle of dilatancy. A series of consolidated and drained shear box tests were conducted with ascending degree of saturation. The reduction of effective apparent cohesion, internal friction angle and dilatancy angle were determined to obtain a threshold of the degree of saturation. All the sand samples had zero residual internal friction angle and/or apparent cohesion after reaching 70% degree of saturation.
基金Supported by the Research Foundation of Ankara University.
文摘The airborne ragweed pollen spectrum was investigated in the air of Ankara, Turkey for aperiod of ten years (1990-1999) using a Burkard seven-day volumetric recording trap. In our study period,long distance transported Ambrosia pollen has been registered. Daily pollen levels varied from low to highin Burge抯 system. In last three years, the pollen concentration of Ambrosia showed a clear increasingtendency. Our results prove that ragweed pollen may be an important threat for ragweed sensitive patientsin Ankara city in near future.
基金Part of this work was financially supported by the EU FP7 Grant FLUNIVAC(Project-ID 602604).
文摘Vectored vaccines based on highly attenuated modified vaccinia Ankara(MVA) are reported to be immunogenic, tolerant to pre-existing immunity, and able to accommodate and stably maintain very large transgenes. MVA is usually produced on primary chicken embryo fibroblasts, but production processes based on continuous cell lines emerge as increasingly robust and cost-effective alternatives. An isolate of a hitherto undescribed genotype was recovered by passage of a nonplaque-purified preparation of MVA in a continuous anatine suspension cell line(CR.pIX) in chemically defined medium.The novel isolate(MVA-CR19) replicated to higher infectious titers in the extracellular volume of suspension cultures and induced fewer syncytia in adherent cultures. We now extend previous studies with the investigation of the point mutations in structural genes of MVA-CR19 and describe an additional point mutation in a regulatory gene. We furthermore map and discuss an extensive rearrangement of the left telomer of MVA-CR19 that appears to have occurred by duplication of the right telomer. This event caused deletions and duplications of genes that may modulate immunologic properties of MVACR19 as a vaccine vector. Our characterizations also highlight the exceptional genetic stability of plaque-purified MVA:although the phenotype of MVA-CR19 appears to be advantageous for replication, we found that all genetic markers that differentiate wildtype and MVA-CR19 are stably maintained in passages of recombinant viruses based on either wildtype or MVA-CR.
文摘The Museum of Anatolian Civilizations in Ankara in Turkey exhibits a glass paste phalera,which seems so far to have largely escaped scholarly attention,being illustrated only in 1990 and given a brief mention in 2017.It is circular with smooth edges which depicts a bust probably of Emperor Claudius with his three children.This glass phalera stands out among the numerous militaria in the Museum of Anatolian Civilizations in Ankara,which so far has not found adequate treatment.Typologically,it fits without difficulty into a series produced in the year AD 43 or shortly after that date.
文摘In today＇s complex web of relations due to the end of the confrontation between the East and West, nuclear materials, technologies, know-how, and scientists have been diffused to states and non-state actors that act irrationally most of the time. The precedent example of nuclear North Korea has given rise to new concerns like whether the low levels of military casualties stemming from nuclear or near-nuclear capable countries will damage the credibility of US/North Atlantic Treaty Organization （NATO） extended deterrence. The ambiguity about how the future of the Iranian Geneva interim agreement will be finalized certainly feeds such kinds of concerns among Tehran＇s neighbors. Till now, both Turkey and South Korea have directly felt and lived through similar kinds of threats. It is true that, during the Cold War years, these two countries have enjoyed the benefit of American assured nuclear security guarantee. However, the current US/NATO extended deterrence due to the mentioned newly arising threats of our times has fallen short of stopping the skirmishes that are occurring at low levels of confrontation. That is why this paper will try to analyze and compare South Korean and Turkish cases so as to comprehend whether there is a necessity to re-think extended deterrence mechanisms that are differently dispatched to meet Ankara＇s and Seoul＇s peculiar security needs.
