The close phylogenetic relationship between humans and non-human primates makes non-human primates an irreplaceable model for the study of human infectious diseases.In this study,we describe the development of a large...The close phylogenetic relationship between humans and non-human primates makes non-human primates an irreplaceable model for the study of human infectious diseases.In this study,we describe the development of a large-scale automatic multi-functional isolation chamber for use with medium-sized laboratory animals carrying infectious diseases.The isolation chamber,including the transfer chain,disinfection chain,negative air pressure isolation system,animal welfare system,and the automated system,is designed to meet all biological safety standards.To create an internal chamber environment that is completely isolated from the exterior,variable frequency drive blowers are used in the air-intake and air-exhaust system,precisely controlling the filtered air flow and providing an air-barrier protection.A double door transfer port is used to transfer material between the interior of the isolation chamber and the outside.A peracetic acid sterilizer and its associated pipeline allow for complete disinfection of the isolation chamber.All of the isolation chamber parameters can be automatically controlled by a programmable computerized menu,allowing for work with different animals in different-sized cages depending on the research project.The large-scale multi-functional isolation chamber provides a useful and safe system for working with infectious medium-sized laboratory animals in high-level bio-safety laboratories.展开更多
Therapeutic experiments are commonly performed on laboratory animals to inves-tigate the possible mechanism(s)of action of toxic agents as well as drugs or sub-stances under consideration.The use of toxins in laborato...Therapeutic experiments are commonly performed on laboratory animals to inves-tigate the possible mechanism(s)of action of toxic agents as well as drugs or sub-stances under consideration.The use of toxins in laboratory animal models,including rats,is intended to cause toxicity.This study aimed to investigate different models of hepatotoxicity and nephrotoxicity in laboratory animals to help researchers advance their research goals.The current narrative review used databases such as Medline,Web of Science,Scopus,and Embase and appropriate keywords until June 2021.Nephrotoxicity and hepatotoxicity models derived from some toxic agents such as cisplatin,acetaminophen,doxorubicin,some anticancer drugs,and other materials through various signaling pathways are investigated.To understand the models of renal or hepatotoxicity in laboratory animals,we have provided a list of toxic agents and their toxicity procedures in this review.展开更多
Laboratory animals and animal experiments are foundations and important support conditions for life sciences, especially for medical research. The animal experiments have drawn extensive attention from the society bec...Laboratory animals and animal experiments are foundations and important support conditions for life sciences, especially for medical research. The animal experiments have drawn extensive attention from the society because of the ethical issue. This paper takes Wenzhou Medical University as an example to give a brief introduction to the ethical review about laboratory animals in the university so as to further draw attention and concerns from the public about the ethical issue of laboratory animals. We successively introduce its scientific projects, nurturing environment and ethical review of laboratory animals.展开更多
State Key Laboratory of Baiyun Obo Rare Earth Resource Researches and Comprehensive Utilization was approved by the Ministry of Science and Technology to be one of the national key laboratories in November 2022.
Objective This study reports the first imported case of Lassa fever(LF)in China.Laboratory detection and molecular epidemiological analysis of the Lassa virus(LASV)from this case offer valuable insights for the preven...Objective This study reports the first imported case of Lassa fever(LF)in China.Laboratory detection and molecular epidemiological analysis of the Lassa virus(LASV)from this case offer valuable insights for the prevention and control of LF.Methods Samples of cerebrospinal fluid(CSF),blood,urine,saliva,and environmental materials were collected from the patient and their close contacts for LASV nucleotide detection.Whole-genome sequencing was performed on positive samples to analyze the genetic characteristics of the virus.Results LASV was detected in the patient’s CSF,blood,and urine,while all samples from close contacts and the environment tested negative.The virus belongs to the lineage IV strain and shares the highest homology with strains from Sierra Leone.The variability in the glycoprotein complex(GPC)among different strains ranged from 3.9%to 15.1%,higher than previously reported for the seven known lineages.Amino acid mutation analysis revealed multiple mutations within the GPC immunogenic epitopes,increasing strain diversity and potentially impacting immune response.Conclusion The case was confirmed through nucleotide detection,with no evidence of secondary transmission or viral spread.The LASV strain identified belongs to lineage IV,with broader GPC variability than previously reported.Mutations in the immune-related sites of GPC may affect immune responses,necessitating heightened vigilance regarding the virus.展开更多
Remembrance activities can support the Culture of Care(CoC)in Laboratory Animal Science(LAS)not only by promoting a culture of respect,gratitude and thankfulness for animal life but also by helping the emotional proce...Remembrance activities can support the Culture of Care(CoC)in Laboratory Animal Science(LAS)not only by promoting a culture of respect,gratitude and thankfulness for animal life but also by helping the emotional processing and healing of lab animal researchers and animal facility staff.Even though remembrance activities are practiced in many parts of the world,we did not come across any reported cases in Sri Lanka before 2022.Therefore,here,we report on the various remembrance activities and practices observed within our local scientific community.展开更多
《Animals and Zoonoses》是一本国际同行评审的、由爱思唯尔提供完全开放存取出版的专业性英文学术期刊(ISSN 2950-2489),由吉林大学主办,现为季刊,主编为我国著名的人兽共患病学专家中国工程院院士金宁一研究员。学报现已具备高起点...《Animals and Zoonoses》是一本国际同行评审的、由爱思唯尔提供完全开放存取出版的专业性英文学术期刊(ISSN 2950-2489),由吉林大学主办,现为季刊,主编为我国著名的人兽共患病学专家中国工程院院士金宁一研究员。学报现已具备高起点新刊的创办条件,将于2024年正式线上线下出版,国内外公开发行。目前学报已组建了包括6位院士在内的由100多位全球著名专家学者组成的高水平编委团队以及近200人的青年编委会,每期均约有一篇由相关领域院士撰写的高水平的学术论文,同时学报通过新媒体、国际著名出版集团爱思唯尔和专家学者等进行精准推广宣传和约稿,目标是利用5~8年的时间进入中科院SCI分区一区顶刊,逐步跨入世界一流学术期刊行列。展开更多
《Animals and Zoonoses》是一本国际同行评审的、由爱思唯尔提供完全开放存取出版的专业性英文学术期刊(ISSN2950-2489),由吉林大学主办,现为季刊,主编为我国著名的人兽共患病学专家中国工程院院士金宁一研究员。学报现已具备高起点新...《Animals and Zoonoses》是一本国际同行评审的、由爱思唯尔提供完全开放存取出版的专业性英文学术期刊(ISSN2950-2489),由吉林大学主办,现为季刊,主编为我国著名的人兽共患病学专家中国工程院院士金宁一研究员。学报现已具备高起点新刊的创办条件,将于2024年正式线上线下出版,国内外公开发行。展开更多
《Animals and Zoonoses》是一本国际同行评审的、由爱思唯尔提供完全开放存取出版的专业性英文学术期刊(ISSN 2950-2489),由吉林大学主办,现为季刊,主编为我国著名的人兽共患病学专家中国工程院院士金宁一研究员。学报现已具备高起点...《Animals and Zoonoses》是一本国际同行评审的、由爱思唯尔提供完全开放存取出版的专业性英文学术期刊(ISSN 2950-2489),由吉林大学主办,现为季刊,主编为我国著名的人兽共患病学专家中国工程院院士金宁一研究员。学报现已具备高起点新刊的创办条件,将于2024年正式线上线下出版,国内外公开发行。展开更多
《Animals and Zoonoses》是一本国际同行评审的、由爱思唯尔提供完全开放存取出版的专业性英文学术期刊(ISSN 2950-2489),由吉林大学主办,现为季刊,主编为我国著名的人兽共患病学专家中国工程院院士金宁一研究员。学报现已具备高起点...《Animals and Zoonoses》是一本国际同行评审的、由爱思唯尔提供完全开放存取出版的专业性英文学术期刊(ISSN 2950-2489),由吉林大学主办,现为季刊,主编为我国著名的人兽共患病学专家中国工程院院士金宁一研究员。学报现已具备高起点新刊的创办条件,将于2024年正式线上线下出版,国内外公开发行。目前学报已组建了包括6位院士在内的由100多位全球著名专家学者组成的高水平编委团队以及近200人的青年编委会,每期均约有一篇由相关领域院士撰写的高水平的学术论文,同时学报通过新媒体、国际著名出版集团爱思唯尔和专家学者等进行精准推广宣传和约稿,目标是利用5~8年的时间进入中科院SCI分区一区顶刊,逐步跨入世界一流学术期刊行列。展开更多
《Animals and Zoonoses》是一本国际同行评审的、由爱思唯尔提供完全开放存取出版的专业性英文学术期刊(ISSN2950-2489),由吉林大学主办,现为季刊,主编为我国著名的人兽共患病学专家中国工程院院士金宁一研究员。学报现已具备高起点新...《Animals and Zoonoses》是一本国际同行评审的、由爱思唯尔提供完全开放存取出版的专业性英文学术期刊(ISSN2950-2489),由吉林大学主办,现为季刊,主编为我国著名的人兽共患病学专家中国工程院院士金宁一研究员。学报现已具备高起点新刊的创办条件,将于2024年正式线上线下出版,国内外公开发行。展开更多
《Animals and Zoonoses》是一本国际同行评审的、由爱思唯尔提供完全开放存取出版的专业性英文学术期刊(ISSN2950-2489),由吉林大学主办,现为季刊,主编为我国著名的人兽共患病学专家中国工程院院士金宁一研究员。学报现已具备高起点新...《Animals and Zoonoses》是一本国际同行评审的、由爱思唯尔提供完全开放存取出版的专业性英文学术期刊(ISSN2950-2489),由吉林大学主办,现为季刊,主编为我国著名的人兽共患病学专家中国工程院院士金宁一研究员。学报现已具备高起点新刊的创办条件,将于2024年正式线上线下出版,国内外公开发行。展开更多
《Animals and Zonoseso》是一本国际同行评审的、由爱思唯尔提供完全开放存取出版的专业性英文学术期刊(ISSN 2950-2489),由吉林大学主办,现为季刊,主编为我国著名的人兽共患病学专家中国工程院院士金宁一研究员。学报现已具备高起点...《Animals and Zonoseso》是一本国际同行评审的、由爱思唯尔提供完全开放存取出版的专业性英文学术期刊(ISSN 2950-2489),由吉林大学主办,现为季刊,主编为我国著名的人兽共患病学专家中国工程院院士金宁一研究员。学报现已具备高起点新刊的创办条件,将于2024年正式线上线下出版,国内外公开发行。目前学报已组建了包括6位院士在内的由100多位全球著名专家学者组成的高水平编委团队以及近200人的青年编委会,每期均约有一篇由相关领域院士撰写的高水平的学术论文,同时学报通过新媒体、国际著名出版集团爱思唯尔和专家学者等进行精准推广宣传和约稿,目标是利用5~8年的时间进入中科院SCI分区一区顶刊,逐步跨入世界一流学术期刊行列。展开更多
《Animals and Zoonoses》是一本国际同行评审的、由爱思唯尔提供完全开放存取出版的专业性英文学术期刊(ISSN 2950-2489),由吉林大学主办,现为季刊,主编为我国著名的人兽共患病学专家中国工程院院士金宁一研究员。学报现已具备高起点...《Animals and Zoonoses》是一本国际同行评审的、由爱思唯尔提供完全开放存取出版的专业性英文学术期刊(ISSN 2950-2489),由吉林大学主办,现为季刊,主编为我国著名的人兽共患病学专家中国工程院院士金宁一研究员。学报现已具备高起点新刊的创办条件,将于2024年正式线上线下出版,国内外公开发行。展开更多
《Animals and Zoonoses》是一本国际同行评审的、由爱思唯尔提供完全开放存取出版的专业性英文学术期刊(ISSN 2950-2489),由吉林大学主办,现为季刊,主编为我国著名的人兽共患病学专家中国工程院院士金宁一研究员。学报现已具备高起点...《Animals and Zoonoses》是一本国际同行评审的、由爱思唯尔提供完全开放存取出版的专业性英文学术期刊(ISSN 2950-2489),由吉林大学主办,现为季刊,主编为我国著名的人兽共患病学专家中国工程院院士金宁一研究员。学报现已具备高起点新刊的创办条件,将于2024年正式线上线下出版,国内外公开发行。展开更多
State Key Laboratory of Baiyun Obo Rare Earth Resource Researches and Comprehensive Utilization was approved by the Ministry of Science and Technology to be one of the national key laboratories in November 2022.The la...State Key Laboratory of Baiyun Obo Rare Earth Resource Researches and Comprehensive Utilization was approved by the Ministry of Science and Technology to be one of the national key laboratories in November 2022.The laboratory was reconstructed based on former State Key Laboratory of Baiyun Obo Rare Earth Resources Researches and Comprehensive Utilization.展开更多
A jungle is full of life.You can sometimes see exhibits of jungle animals and learn about them.Monkeys play in jungle trees.Colorful parrots fly and call to one another.Black and orange tigers hunt under the trees.
This study describes the design and performance of a laboratory-based tender X-ray spectrometer for X-ray absorption spectroscopy.The system enables effective absorption spectra to be measured within the 2.0-9.0 keV r...This study describes the design and performance of a laboratory-based tender X-ray spectrometer for X-ray absorption spectroscopy.The system enables effective absorption spectra to be measured within the 2.0-9.0 keV range using Rowland circle geometry;it covers the K edge of 3d transition metals,the L edge of lanthanides,and the M edge of actinides.The spectrometer is configured with a Rowland circle with a diameter of 500 mm and integrates a 250 W liquid metal jet X-ray source,spherical bent crystal analyzer,and energy-resolving silicon drift detector.The X-ray source is installed outside the vacuum chamber and remains fixed,while the analyzer crystals and detector are adjusted to change the Bragg angle,maintaining the Rowland condition.The energy resolution is 0.36-1.30 eV at 2.0-9.0 keV,and the monochromatic flux is approximately 5×10^(5) counts/s at 7040 eV.This study highlights the primary characteristics of the spectrometer and demon-strates its capabilities using selected experimental examples.The successful development of this spectrometer can facilitate research on actinide elements,which are often constrained in synchrotron radiation experiments owing to their radioactivity,thus fostering advancements in related nuclear energy fields.展开更多
Against the backdrop of the digital era,information technology is constantly evolving.Among various technologies,EDA(Electronic Design Automation)technology provides strong support for integrated circuit design and el...Against the backdrop of the digital era,information technology is constantly evolving.Among various technologies,EDA(Electronic Design Automation)technology provides strong support for integrated circuit design and electronic system development,demonstrating significant value.Colleges and universities are key institutions for cultivating computer professionals.By building high-level EDA laboratories,they can effectively improve the effectiveness of teaching and train talents that meet industry demands.From the perspective of computer majors in colleges and universities,this paper discusses the construction objectives of EDA laboratories and proposes specific practical strategies.The purpose is to provide feasible references for the construction of Eda laboratories,effectively enhance the quality of professional talent cultivation,and offer insights for the subsequent teaching reform of computer majors.展开更多
基金Project supported by the Scientific Research Foundation for Returned Overseas Chinese Scholars, State Education Ministry (No. 2008-890-2)the National Natural Science Foundation of China (No. 30972633)
文摘The close phylogenetic relationship between humans and non-human primates makes non-human primates an irreplaceable model for the study of human infectious diseases.In this study,we describe the development of a large-scale automatic multi-functional isolation chamber for use with medium-sized laboratory animals carrying infectious diseases.The isolation chamber,including the transfer chain,disinfection chain,negative air pressure isolation system,animal welfare system,and the automated system,is designed to meet all biological safety standards.To create an internal chamber environment that is completely isolated from the exterior,variable frequency drive blowers are used in the air-intake and air-exhaust system,precisely controlling the filtered air flow and providing an air-barrier protection.A double door transfer port is used to transfer material between the interior of the isolation chamber and the outside.A peracetic acid sterilizer and its associated pipeline allow for complete disinfection of the isolation chamber.All of the isolation chamber parameters can be automatically controlled by a programmable computerized menu,allowing for work with different animals in different-sized cages depending on the research project.The large-scale multi-functional isolation chamber provides a useful and safe system for working with infectious medium-sized laboratory animals in high-level bio-safety laboratories.
文摘Therapeutic experiments are commonly performed on laboratory animals to inves-tigate the possible mechanism(s)of action of toxic agents as well as drugs or sub-stances under consideration.The use of toxins in laboratory animal models,including rats,is intended to cause toxicity.This study aimed to investigate different models of hepatotoxicity and nephrotoxicity in laboratory animals to help researchers advance their research goals.The current narrative review used databases such as Medline,Web of Science,Scopus,and Embase and appropriate keywords until June 2021.Nephrotoxicity and hepatotoxicity models derived from some toxic agents such as cisplatin,acetaminophen,doxorubicin,some anticancer drugs,and other materials through various signaling pathways are investigated.To understand the models of renal or hepatotoxicity in laboratory animals,we have provided a list of toxic agents and their toxicity procedures in this review.
基金supported by fund of science and technology project of Wenzhou(Y20140601)
文摘Laboratory animals and animal experiments are foundations and important support conditions for life sciences, especially for medical research. The animal experiments have drawn extensive attention from the society because of the ethical issue. This paper takes Wenzhou Medical University as an example to give a brief introduction to the ethical review about laboratory animals in the university so as to further draw attention and concerns from the public about the ethical issue of laboratory animals. We successively introduce its scientific projects, nurturing environment and ethical review of laboratory animals.
文摘State Key Laboratory of Baiyun Obo Rare Earth Resource Researches and Comprehensive Utilization was approved by the Ministry of Science and Technology to be one of the national key laboratories in November 2022.
基金supported by Public Health Talent Training and Surport Plan(National Administration of Disease Prevention and Control)Research and application of new technology for rapid monitoring and tracing of emergent infectious diseases among entry-exit population(2024YFFK0056)Monitoring,Early warning and Response of Major Infectious Diseases(2022ZDZX0017).
文摘Objective This study reports the first imported case of Lassa fever(LF)in China.Laboratory detection and molecular epidemiological analysis of the Lassa virus(LASV)from this case offer valuable insights for the prevention and control of LF.Methods Samples of cerebrospinal fluid(CSF),blood,urine,saliva,and environmental materials were collected from the patient and their close contacts for LASV nucleotide detection.Whole-genome sequencing was performed on positive samples to analyze the genetic characteristics of the virus.Results LASV was detected in the patient’s CSF,blood,and urine,while all samples from close contacts and the environment tested negative.The virus belongs to the lineage IV strain and shares the highest homology with strains from Sierra Leone.The variability in the glycoprotein complex(GPC)among different strains ranged from 3.9%to 15.1%,higher than previously reported for the seven known lineages.Amino acid mutation analysis revealed multiple mutations within the GPC immunogenic epitopes,increasing strain diversity and potentially impacting immune response.Conclusion The case was confirmed through nucleotide detection,with no evidence of secondary transmission or viral spread.The LASV strain identified belongs to lineage IV,with broader GPC variability than previously reported.Mutations in the immune-related sites of GPC may affect immune responses,necessitating heightened vigilance regarding the virus.
文摘Remembrance activities can support the Culture of Care(CoC)in Laboratory Animal Science(LAS)not only by promoting a culture of respect,gratitude and thankfulness for animal life but also by helping the emotional processing and healing of lab animal researchers and animal facility staff.Even though remembrance activities are practiced in many parts of the world,we did not come across any reported cases in Sri Lanka before 2022.Therefore,here,we report on the various remembrance activities and practices observed within our local scientific community.
文摘《Animals and Zoonoses》是一本国际同行评审的、由爱思唯尔提供完全开放存取出版的专业性英文学术期刊(ISSN 2950-2489),由吉林大学主办,现为季刊,主编为我国著名的人兽共患病学专家中国工程院院士金宁一研究员。学报现已具备高起点新刊的创办条件,将于2024年正式线上线下出版,国内外公开发行。目前学报已组建了包括6位院士在内的由100多位全球著名专家学者组成的高水平编委团队以及近200人的青年编委会,每期均约有一篇由相关领域院士撰写的高水平的学术论文,同时学报通过新媒体、国际著名出版集团爱思唯尔和专家学者等进行精准推广宣传和约稿,目标是利用5~8年的时间进入中科院SCI分区一区顶刊,逐步跨入世界一流学术期刊行列。
文摘《Animals and Zoonoses》是一本国际同行评审的、由爱思唯尔提供完全开放存取出版的专业性英文学术期刊(ISSN2950-2489),由吉林大学主办,现为季刊,主编为我国著名的人兽共患病学专家中国工程院院士金宁一研究员。学报现已具备高起点新刊的创办条件,将于2024年正式线上线下出版,国内外公开发行。
文摘《Animals and Zoonoses》是一本国际同行评审的、由爱思唯尔提供完全开放存取出版的专业性英文学术期刊(ISSN 2950-2489),由吉林大学主办,现为季刊,主编为我国著名的人兽共患病学专家中国工程院院士金宁一研究员。学报现已具备高起点新刊的创办条件,将于2024年正式线上线下出版,国内外公开发行。
文摘《Animals and Zoonoses》是一本国际同行评审的、由爱思唯尔提供完全开放存取出版的专业性英文学术期刊(ISSN 2950-2489),由吉林大学主办,现为季刊,主编为我国著名的人兽共患病学专家中国工程院院士金宁一研究员。学报现已具备高起点新刊的创办条件,将于2024年正式线上线下出版,国内外公开发行。目前学报已组建了包括6位院士在内的由100多位全球著名专家学者组成的高水平编委团队以及近200人的青年编委会,每期均约有一篇由相关领域院士撰写的高水平的学术论文,同时学报通过新媒体、国际著名出版集团爱思唯尔和专家学者等进行精准推广宣传和约稿,目标是利用5~8年的时间进入中科院SCI分区一区顶刊,逐步跨入世界一流学术期刊行列。
文摘《Animals and Zoonoses》是一本国际同行评审的、由爱思唯尔提供完全开放存取出版的专业性英文学术期刊(ISSN2950-2489),由吉林大学主办,现为季刊,主编为我国著名的人兽共患病学专家中国工程院院士金宁一研究员。学报现已具备高起点新刊的创办条件,将于2024年正式线上线下出版,国内外公开发行。
文摘《Animals and Zoonoses》是一本国际同行评审的、由爱思唯尔提供完全开放存取出版的专业性英文学术期刊(ISSN2950-2489),由吉林大学主办,现为季刊,主编为我国著名的人兽共患病学专家中国工程院院士金宁一研究员。学报现已具备高起点新刊的创办条件,将于2024年正式线上线下出版,国内外公开发行。
文摘《Animals and Zonoseso》是一本国际同行评审的、由爱思唯尔提供完全开放存取出版的专业性英文学术期刊(ISSN 2950-2489),由吉林大学主办,现为季刊,主编为我国著名的人兽共患病学专家中国工程院院士金宁一研究员。学报现已具备高起点新刊的创办条件,将于2024年正式线上线下出版,国内外公开发行。目前学报已组建了包括6位院士在内的由100多位全球著名专家学者组成的高水平编委团队以及近200人的青年编委会,每期均约有一篇由相关领域院士撰写的高水平的学术论文,同时学报通过新媒体、国际著名出版集团爱思唯尔和专家学者等进行精准推广宣传和约稿,目标是利用5~8年的时间进入中科院SCI分区一区顶刊,逐步跨入世界一流学术期刊行列。
文摘《Animals and Zoonoses》是一本国际同行评审的、由爱思唯尔提供完全开放存取出版的专业性英文学术期刊(ISSN 2950-2489),由吉林大学主办,现为季刊,主编为我国著名的人兽共患病学专家中国工程院院士金宁一研究员。学报现已具备高起点新刊的创办条件,将于2024年正式线上线下出版,国内外公开发行。
文摘《Animals and Zoonoses》是一本国际同行评审的、由爱思唯尔提供完全开放存取出版的专业性英文学术期刊(ISSN 2950-2489),由吉林大学主办,现为季刊,主编为我国著名的人兽共患病学专家中国工程院院士金宁一研究员。学报现已具备高起点新刊的创办条件,将于2024年正式线上线下出版,国内外公开发行。
文摘State Key Laboratory of Baiyun Obo Rare Earth Resource Researches and Comprehensive Utilization was approved by the Ministry of Science and Technology to be one of the national key laboratories in November 2022.The laboratory was reconstructed based on former State Key Laboratory of Baiyun Obo Rare Earth Resources Researches and Comprehensive Utilization.
文摘A jungle is full of life.You can sometimes see exhibits of jungle animals and learn about them.Monkeys play in jungle trees.Colorful parrots fly and call to one another.Black and orange tigers hunt under the trees.
基金supported by the Instrument and Equipment Development Program of the Chinese Academy of Science(Grant No.YJKYYQ20180066)the National Natural Science Foundation of China(No.22227809)+2 种基金the Shanghai Science and Technology Innovation Action Plan(No.22142200300)the Science and Technology Talents Program of the Shanghai Institute of Applied Physics(No.SINAP-KJZX-202204)the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDA 0400000).
文摘This study describes the design and performance of a laboratory-based tender X-ray spectrometer for X-ray absorption spectroscopy.The system enables effective absorption spectra to be measured within the 2.0-9.0 keV range using Rowland circle geometry;it covers the K edge of 3d transition metals,the L edge of lanthanides,and the M edge of actinides.The spectrometer is configured with a Rowland circle with a diameter of 500 mm and integrates a 250 W liquid metal jet X-ray source,spherical bent crystal analyzer,and energy-resolving silicon drift detector.The X-ray source is installed outside the vacuum chamber and remains fixed,while the analyzer crystals and detector are adjusted to change the Bragg angle,maintaining the Rowland condition.The energy resolution is 0.36-1.30 eV at 2.0-9.0 keV,and the monochromatic flux is approximately 5×10^(5) counts/s at 7040 eV.This study highlights the primary characteristics of the spectrometer and demon-strates its capabilities using selected experimental examples.The successful development of this spectrometer can facilitate research on actinide elements,which are often constrained in synchrotron radiation experiments owing to their radioactivity,thus fostering advancements in related nuclear energy fields.
基金Research Project on Higher Education Teaching Reform in Heilongjiang Province,Construction of Cloud-based Virtual-Physical Integrated Experimental Environment and Inter-university Collaborative Innovation and Practice(Project No.:SJGYB2024285)。
文摘Against the backdrop of the digital era,information technology is constantly evolving.Among various technologies,EDA(Electronic Design Automation)technology provides strong support for integrated circuit design and electronic system development,demonstrating significant value.Colleges and universities are key institutions for cultivating computer professionals.By building high-level EDA laboratories,they can effectively improve the effectiveness of teaching and train talents that meet industry demands.From the perspective of computer majors in colleges and universities,this paper discusses the construction objectives of EDA laboratories and proposes specific practical strategies.The purpose is to provide feasible references for the construction of Eda laboratories,effectively enhance the quality of professional talent cultivation,and offer insights for the subsequent teaching reform of computer majors.
