The research introduced Paeonia suffruticosa industry from market demand, value and adaptability and its characteristics, providing references for Paeonia suffruticosa industrialization from product aspect. Finally, i...The research introduced Paeonia suffruticosa industry from market demand, value and adaptability and its characteristics, providing references for Paeonia suffruticosa industrialization from product aspect. Finally, its development models were proposed, as well as countermeasures, providing suggestions and countermeasures for Paeonia suffruticosa industry.展开更多
Aims and Scope Asian Journal of Andrology(AJA)launched in 1999,is aninternational peer-reviewed open-access journal devoted to basicand clinical andrology and related sciences.AJA is sponsored by theShanghai Institute...Aims and Scope Asian Journal of Andrology(AJA)launched in 1999,is aninternational peer-reviewed open-access journal devoted to basicand clinical andrology and related sciences.AJA is sponsored by theShanghai Institute of Materia Medica at the Chinese Academy ofSciences(SIMM)and Shanghai Jiao Tong University(SJTU).AJAhas Advanced Online Publication service and publishes in printbimonthly.The Editor-in-Chief of AJA is Professor Jin-Song Li fromthe Center for Excellence in Molecular Cell Science at the ChineseAcademy of Sciences.展开更多
Aims and Scope Asian Journal of Andrology(AJA)launched in 1999,is an international peer-reviewed open-access journal devoted to basic and clinical andrology and related sciences.AJA is sponsored by the Shanghai Instit...Aims and Scope Asian Journal of Andrology(AJA)launched in 1999,is an international peer-reviewed open-access journal devoted to basic and clinical andrology and related sciences.AJA is sponsored by the Shanghai Institute of Materia Medica at the Chinese Academy of Sciences(SIMM)and Shanghai Jiao Tong University(SJTU).展开更多
Asian Journal of Andrology(AJA)launched in 1999,is an international peer-reviewed open-access journal devoted to basic and clinical andrology and related sciences.AJA is sponsored by the Shanghai Institute of Materia ...Asian Journal of Andrology(AJA)launched in 1999,is an international peer-reviewed open-access journal devoted to basic and clinical andrology and related sciences.AJA is sponsored by the Shanghai Institute of Materia Medica at the Chinese Academy of Sciences(SIMM)and Shanghai Jiao Tong University(SJTU).AJA has an Advanced Online Publication service and publishes in print bimonthly.The Editor-in-Chief of AJA is Professor Jin-Song Li from the Center for Excellence in Molecular Cell Science at the Chinese Academy of Sciences.展开更多
This study measured the antioxidant enzyme activities of Pyrola under cold and endophytic fungal infection conditions[i.e.,peroxidase(POD),catalase(CAT)and superoxide dismutase(SOD)],and the contents of malondialdehyd...This study measured the antioxidant enzyme activities of Pyrola under cold and endophytic fungal infection conditions[i.e.,peroxidase(POD),catalase(CAT)and superoxide dismutase(SOD)],and the contents of malondialdehyde(MDA),soluble sugar and soluble protein.In addition,the changes in the anatomical structure of Pyrola vegetable organ during cold stress upon inoculation with a synergistic endophytic fungus were also analyzed.It was found that the soluble sugar and soluble protein contents and POD,SOD and CAT activies of Pyrola all increased,when the plants were exposed to temperature of-5℃.In particular,the MDA contents and the POD activies significantly increased compared with those of the control.In addition,the soluble sugar and soluble protein contents increased during the treatment,which involved in both inoculation with an endophytic fungus and low temperature;however,with a reduction in the concentration of endophytic fungus,those two indicators decreased.The optimal concentration of endophytic fungus was 5×10^(7) cfu·mL^(-1).From the anatomical structure of Pyrola root,endophytic fungi were found to improve the health of.Pyrola in cold weather.These results showed that endophytic fungi played a vital role in the growth of Pyrola,which was an evergreen plant that could survive exposure to low temperature.展开更多
André Gide is one of the most important writers in the history of French literature in the 20th century.His works are highly distinctive:on the one hand,there is strong coherence and beautiful language between hi...André Gide is one of the most important writers in the history of French literature in the 20th century.His works are highly distinctive:on the one hand,there is strong coherence and beautiful language between his works,which gives them a strong musicality.On the other hand,his works delve deeper into the struggle between the“soul”and the“body”under the oppression of“religious concepts”,which is most evident in one of his representative works:Pastoral Symphony.This article will analyze and explore the contradiction between“soul”and“body”reflected in the work of“Pastoral Symphony”from three aspects:“modernity”,“aesthetics”,and“characters’prototypes”.展开更多
Neuraminidase inhibitors(NAIs)are the mainstay antiviral drugs against influenza infection.In this study,a ligand fishing protocol was developed to screen NAIs using neuraminidase immobilized magnetic beads(NA-MB).Aft...Neuraminidase inhibitors(NAIs)are the mainstay antiviral drugs against influenza infection.In this study,a ligand fishing protocol was developed to screen NAIs using neuraminidase immobilized magnetic beads(NA-MB).After verifying the feasibility of NA-MB with an artificial mixture including NA inhibitors and non-inhibitors,the developed ligand fishing protocol was applied to screen NAIs from the crude extracts of Duchesnea indica Andr.Twenty-four NA binding compounds were identified from the normal butanol(n-BuOH)extract of D.indica as potential NAIs by high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry(HPLC-Q-TOF-MS)assisted with Compound Structure Identification(CSI):FingerID,including 12 ellagitannins,4 brevifolin derivatives,3 ellagic acid derivatives,and 4 flavonoids.Among them,9 compounds were isolated and tested for in vitro NA inhibitory activities against NA from Clostridium perfringens,and from oseltamivir sensitive and resistant influenza A virus strains.The results indicate that compound B23 has the NA inhibitory activities in both the oseltamivir sensitive and resistant viral NA,with half maximal inhibitory concentration(IC50)values of 197.9 and 125.4μmol/L,respectively.Moreover,B23 can obviously reduce the replication of oseltamivir sensitive and resistant viruses in Madin-Darby canine kidney(MDCK)cells at the concentrations of 40 and 200μmol/L.展开更多
基金Supported by Financial Special Fund of Tianjin~~
文摘The research introduced Paeonia suffruticosa industry from market demand, value and adaptability and its characteristics, providing references for Paeonia suffruticosa industrialization from product aspect. Finally, its development models were proposed, as well as countermeasures, providing suggestions and countermeasures for Paeonia suffruticosa industry.
文摘Aims and Scope Asian Journal of Andrology(AJA)launched in 1999,is aninternational peer-reviewed open-access journal devoted to basicand clinical andrology and related sciences.AJA is sponsored by theShanghai Institute of Materia Medica at the Chinese Academy ofSciences(SIMM)and Shanghai Jiao Tong University(SJTU).AJAhas Advanced Online Publication service and publishes in printbimonthly.The Editor-in-Chief of AJA is Professor Jin-Song Li fromthe Center for Excellence in Molecular Cell Science at the ChineseAcademy of Sciences.
文摘Aims and Scope Asian Journal of Andrology(AJA)launched in 1999,is an international peer-reviewed open-access journal devoted to basic and clinical andrology and related sciences.AJA is sponsored by the Shanghai Institute of Materia Medica at the Chinese Academy of Sciences(SIMM)and Shanghai Jiao Tong University(SJTU).
文摘Asian Journal of Andrology(AJA)launched in 1999,is an international peer-reviewed open-access journal devoted to basic and clinical andrology and related sciences.AJA is sponsored by the Shanghai Institute of Materia Medica at the Chinese Academy of Sciences(SIMM)and Shanghai Jiao Tong University(SJTU).AJA has an Advanced Online Publication service and publishes in print bimonthly.The Editor-in-Chief of AJA is Professor Jin-Song Li from the Center for Excellence in Molecular Cell Science at the Chinese Academy of Sciences.
基金Supported by Postdoctoral Scientific Research Foundation Project Settled in Heilongjiang Province(LBH-Q11153)。
文摘This study measured the antioxidant enzyme activities of Pyrola under cold and endophytic fungal infection conditions[i.e.,peroxidase(POD),catalase(CAT)and superoxide dismutase(SOD)],and the contents of malondialdehyde(MDA),soluble sugar and soluble protein.In addition,the changes in the anatomical structure of Pyrola vegetable organ during cold stress upon inoculation with a synergistic endophytic fungus were also analyzed.It was found that the soluble sugar and soluble protein contents and POD,SOD and CAT activies of Pyrola all increased,when the plants were exposed to temperature of-5℃.In particular,the MDA contents and the POD activies significantly increased compared with those of the control.In addition,the soluble sugar and soluble protein contents increased during the treatment,which involved in both inoculation with an endophytic fungus and low temperature;however,with a reduction in the concentration of endophytic fungus,those two indicators decreased.The optimal concentration of endophytic fungus was 5×10^(7) cfu·mL^(-1).From the anatomical structure of Pyrola root,endophytic fungi were found to improve the health of.Pyrola in cold weather.These results showed that endophytic fungi played a vital role in the growth of Pyrola,which was an evergreen plant that could survive exposure to low temperature.
基金This essay is supported by the China Scholarship Council Program(ID:202408440417).
文摘André Gide is one of the most important writers in the history of French literature in the 20th century.His works are highly distinctive:on the one hand,there is strong coherence and beautiful language between his works,which gives them a strong musicality.On the other hand,his works delve deeper into the struggle between the“soul”and the“body”under the oppression of“religious concepts”,which is most evident in one of his representative works:Pastoral Symphony.This article will analyze and explore the contradiction between“soul”and“body”reflected in the work of“Pastoral Symphony”from three aspects:“modernity”,“aesthetics”,and“characters’prototypes”.
基金financially supported by National Natural Science Foundation,China(81872830,31970884,and U1801287)the International Science&Technology Cooperation Program of Guangzhou,China(201807010022)National Natural Science Foundation of Guangdong Province,China(No.2019A1515011489)
文摘Neuraminidase inhibitors(NAIs)are the mainstay antiviral drugs against influenza infection.In this study,a ligand fishing protocol was developed to screen NAIs using neuraminidase immobilized magnetic beads(NA-MB).After verifying the feasibility of NA-MB with an artificial mixture including NA inhibitors and non-inhibitors,the developed ligand fishing protocol was applied to screen NAIs from the crude extracts of Duchesnea indica Andr.Twenty-four NA binding compounds were identified from the normal butanol(n-BuOH)extract of D.indica as potential NAIs by high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry(HPLC-Q-TOF-MS)assisted with Compound Structure Identification(CSI):FingerID,including 12 ellagitannins,4 brevifolin derivatives,3 ellagic acid derivatives,and 4 flavonoids.Among them,9 compounds were isolated and tested for in vitro NA inhibitory activities against NA from Clostridium perfringens,and from oseltamivir sensitive and resistant influenza A virus strains.The results indicate that compound B23 has the NA inhibitory activities in both the oseltamivir sensitive and resistant viral NA,with half maximal inhibitory concentration(IC50)values of 197.9 and 125.4μmol/L,respectively.Moreover,B23 can obviously reduce the replication of oseltamivir sensitive and resistant viruses in Madin-Darby canine kidney(MDCK)cells at the concentrations of 40 and 200μmol/L.
