Background: Hypnosis monitoring has been shown to reduce the incidence of awareness. A-line ARX-IndexTM (AAI) derived from auditory evoked potentials (AEP) represents as a numerical variable depth of anaesthesia. Obje...Background: Hypnosis monitoring has been shown to reduce the incidence of awareness. A-line ARX-IndexTM (AAI) derived from auditory evoked potentials (AEP) represents as a numerical variable depth of anaesthesia. Objectives: To study the efficacy of AEP as an indicator of anaesthetic depth and monitor intraoperative awareness in neurosurgical patients by using the AAI scale. Design: Prospective cohort study is used. Setting: The study is in Neurosurgical centre of Tertiary care hospital. Participants: Neurosurgical patients requiring general anaesthesia with duration of surgery between 90 - 150 minutes were enrolled for the study. Intervention: Patients in Group 1 (control) were monitored by conventional methods. Patients in Group 2 (study) underwent intraoperative monitoring by using the AEP monitor. Primary outcome: To study the efficacy of AEP monitoring and AAI index for monitoring the depth of anaesthesia and reducing the incidence of awareness. Results: There was no significant difference in the intraoperative haemodynamic responses measured between the two study groups (p > 0.5). There was no significant difference in the identification of intraoperative awareness by using conventional parameters between the two groups (p > 0.5). There was also a significantly faster time to recovery for patients in Group 2 (p < 0.05). Conclusion: Hypnosis monitoring using AEP monitor/AAI in neurosurgical patients under general anaesthesia did not show any significant difference in haemodynamic response and intraoperative awareness but had significant lower consumption of volatile anaesthetic with cost sparing effect and a faster recovery time as compared to conventional monitoring.展开更多
This paper reviews the existing depth of anaesthesia(DoA) monitors and their algorithms and also proposes to improve their performance from four aspects.\n ideal DoA monitor should be able to suggest a personalised dr...This paper reviews the existing depth of anaesthesia(DoA) monitors and their algorithms and also proposes to improve their performance from four aspects.\n ideal DoA monitor should be able to suggest a personalised drug dosages,to predict and provide early warnings when dosages are inappropriate,to he porlalile and highty cost—effective.The limitations of the existing DoA monitors commonly include unsatisfied data filtering techniques.time delay for the monitoring responses,and inflexible and low noise immunity problems.The latest research results show that their performance can be improved using up—to—date computing technology and neurophysiology.The findings in Chinese market review show that neither the imported nor the Chinese domestic DoA monitors are widely utilised at hospitals.but the demand for DoA monitors is very high.Clearly there is a high demand which encourages the development of a better DoA monitor and its mass production in China.展开更多
目的探讨意识指数(index of consciousness,IoC)在小儿全身麻醉诱导时镇静深度监测中的应用价值。方法 25例择期手术患儿,应用丙泊酚等进行麻醉诱导,麻醉诱导期间测试患儿意识反应,镇静深度采用镇静/警觉评分(observers assessment of a...目的探讨意识指数(index of consciousness,IoC)在小儿全身麻醉诱导时镇静深度监测中的应用价值。方法 25例择期手术患儿,应用丙泊酚等进行麻醉诱导,麻醉诱导期间测试患儿意识反应,镇静深度采用镇静/警觉评分(observers assessment of alertness/sedation scale,OAA/S),记录OAA/S评分即刻的IoC,并与脑电双频谱指数(bispectral index,BIS)进行比较。结果25例中有效数据17例;OAA/S为0分时IoC值(44.82±8.47)、BIS值(39.00±14.44)均低于OAA/S为5分时(IoC值为96.65±2.64,BIS值为90.24±5.83),差异有统计学意义(P<0.01),且以上2个时间点IoC值均大于BIS值(P<0.05);OAA/S与IoC(r=0.871,P=0.000)、BIS(r=0.864,P=0.000)以及IoC与BIS(r=0.805,P=0.002)均呈正相关。结论 IoC值可反映丙泊酚麻醉诱导期间小儿镇静深度。展开更多
文摘Background: Hypnosis monitoring has been shown to reduce the incidence of awareness. A-line ARX-IndexTM (AAI) derived from auditory evoked potentials (AEP) represents as a numerical variable depth of anaesthesia. Objectives: To study the efficacy of AEP as an indicator of anaesthetic depth and monitor intraoperative awareness in neurosurgical patients by using the AAI scale. Design: Prospective cohort study is used. Setting: The study is in Neurosurgical centre of Tertiary care hospital. Participants: Neurosurgical patients requiring general anaesthesia with duration of surgery between 90 - 150 minutes were enrolled for the study. Intervention: Patients in Group 1 (control) were monitored by conventional methods. Patients in Group 2 (study) underwent intraoperative monitoring by using the AEP monitor. Primary outcome: To study the efficacy of AEP monitoring and AAI index for monitoring the depth of anaesthesia and reducing the incidence of awareness. Results: There was no significant difference in the intraoperative haemodynamic responses measured between the two study groups (p > 0.5). There was no significant difference in the identification of intraoperative awareness by using conventional parameters between the two groups (p > 0.5). There was also a significantly faster time to recovery for patients in Group 2 (p < 0.05). Conclusion: Hypnosis monitoring using AEP monitor/AAI in neurosurgical patients under general anaesthesia did not show any significant difference in haemodynamic response and intraoperative awareness but had significant lower consumption of volatile anaesthetic with cost sparing effect and a faster recovery time as compared to conventional monitoring.
文摘This paper reviews the existing depth of anaesthesia(DoA) monitors and their algorithms and also proposes to improve their performance from four aspects.\n ideal DoA monitor should be able to suggest a personalised drug dosages,to predict and provide early warnings when dosages are inappropriate,to he porlalile and highty cost—effective.The limitations of the existing DoA monitors commonly include unsatisfied data filtering techniques.time delay for the monitoring responses,and inflexible and low noise immunity problems.The latest research results show that their performance can be improved using up—to—date computing technology and neurophysiology.The findings in Chinese market review show that neither the imported nor the Chinese domestic DoA monitors are widely utilised at hospitals.but the demand for DoA monitors is very high.Clearly there is a high demand which encourages the development of a better DoA monitor and its mass production in China.
文摘目的探讨意识指数(index of consciousness,IoC)在小儿全身麻醉诱导时镇静深度监测中的应用价值。方法 25例择期手术患儿,应用丙泊酚等进行麻醉诱导,麻醉诱导期间测试患儿意识反应,镇静深度采用镇静/警觉评分(observers assessment of alertness/sedation scale,OAA/S),记录OAA/S评分即刻的IoC,并与脑电双频谱指数(bispectral index,BIS)进行比较。结果25例中有效数据17例;OAA/S为0分时IoC值(44.82±8.47)、BIS值(39.00±14.44)均低于OAA/S为5分时(IoC值为96.65±2.64,BIS值为90.24±5.83),差异有统计学意义(P<0.01),且以上2个时间点IoC值均大于BIS值(P<0.05);OAA/S与IoC(r=0.871,P=0.000)、BIS(r=0.864,P=0.000)以及IoC与BIS(r=0.805,P=0.002)均呈正相关。结论 IoC值可反映丙泊酚麻醉诱导期间小儿镇静深度。