BACKGROUND Due to the dry and cold climate,the obvious temperature difference between day and night,and the low oxygen content of the air in the plateau area,people are prone to upper respiratory tract diseases,and of...BACKGROUND Due to the dry and cold climate,the obvious temperature difference between day and night,and the low oxygen content of the air in the plateau area,people are prone to upper respiratory tract diseases,and often the condition is prolonged,and the patients are prone to anxiety and uneasiness,which may be related to the harshness of the plateau environment,somatic discomfort due to the lack of oxygen,anxiety about the disease,and other factors.AIM To investigate the effects of cognitive behavioral therapy(CBT)on anxiety,sleep disorders,and hypoxia tolerance in patients with high-altitude respiratory diseases.METHODS A total of 2337 patients with high-altitude-related respiratory diseases treated at our hospital between November 2023 and January 2024 were selected as the study subjects.The subjects’pre-high-altitude residential altitude was approximately 1700 meters.They were divided into two groups.Both groups were given symptomatic treatment,and the control group implemented conventional nursing intervention,while the research group simultaneously conducted CBT intervention;assessed the degree of health knowledge of the two groups,and applied the Hamilton Anxiety Scale and the Pittsburgh Sleep Quality Index to assess the anxiety and sleep quality of the patients before and after the intervention,respectively.It also observed the length and efficiency of sleep,and detected the level of serum hypoxia inducible factor-1α,erythropoietin(EPO)and clinical intervention before and after intervention.EPO levels,and investigated satisfaction with the clinical intervention.RESULTS The rate of excellent health knowledge in the intervention group was 93.64%,which was higher than that in the control group(74.23%;P<0.05).Before the intervention,there was no significant difference in Hamilton Anxiety Scale and Pittsburgh Sleep Quality Index scores between the two groups(P>0.05),and after the intervention,the scores of the study group were significantly lower than those of the control group(P<0.05).There was no significant difference in sleep duration and sleep efficiency between the groups before the intervention(P>0.05),and after the intervention,the scores of the study group were significantly larger than those of the control group(P<0.05).There was no significant difference in serum hypoxia inducible factor-1αand EPO between the two groups before intervention(P>0.05),and both research groups were significantly lower than the control group after intervention(P<0.05).According to the questionnaire survey,the intervention satisfaction of the study group was 95.53%,which was higher than that of the control group(80.14%;P<0.05).CONCLUSION The CBT intervention in the treatment of patients with high-altitude-related respiratory diseases helps improve patients'health knowledge,relieve anxiety,improve sleep quality and hypoxia tolerance,and improve nursing satisfaction.展开更多
The number of people travelling to high-altitude areas or participating in mountain sports is increasing.For individuals visiting such terrains for the first time,the lack of adaptation to the hypobaric hypoxic enviro...The number of people travelling to high-altitude areas or participating in mountain sports is increasing.For individuals visiting such terrains for the first time,the lack of adaptation to the hypobaric hypoxic environment can lead to the deterioration of gastrointestinal function and barriers.In more severe cases,this lack of acclimatisation may lead to acute high-altitude illness.At present,the prevention and treatment of these issues primarily revolve around strategies such as descending to lower altitudes,oxygen supplementation,and medication.However,the available intervention measures to prevent health problems resulting from high-altitude environments remain limited.In this review,we discuss common altitude-related illnesses,including gastrointestinal problems.Moreover,we explore the potential of commonly used medications and dietary supplements in alleviating altitude-related issues.This review can provide a basis for future research on modulating the gut microbiota for mitigating high-altitude illness.展开更多
Traffic engineering such as tunnels in various altitudinal gradient zone are at risk of accidental explosion,which can damage personnel and equipment.Accurate prediction of the distribution pattern of explosive loads ...Traffic engineering such as tunnels in various altitudinal gradient zone are at risk of accidental explosion,which can damage personnel and equipment.Accurate prediction of the distribution pattern of explosive loads and shock wave propagation process in semi-enclosed structures at various altitude environment is key research focus in the fields of explosion shock and fluid dynamics.The effect of altitude on the propagation of shock waves in tunnels was investigated by conducting explosion test and numerical simulation.Based on the experimental and numerical simulation results,a prediction model for the attenuation of the peak overpressure of tunnel shock waves at different altitudes was established.The results showed that the peak overpressure decreased at the same measurement points in the tunnel entrance under the high altitude condition.In contrast,an increase in altitude accelerated the propagation speed of the shock wave in the tunnel.The average error between the peak shock wave overpressure obtained using the overpressure prediction formula and the measured test data was less than15%,the average error between the propagation velocity of shock waves predicted values and the test data is less than 10%.The method can effectively predict the overpressure attenuation of blast wave in tunnel at various altitudes.展开更多
The ability of queens and males of most ant species to disperse by flight has fundamentally contributed to the group’s evolutionary and ecological success and is a determining factor to take into account for biogeogr...The ability of queens and males of most ant species to disperse by flight has fundamentally contributed to the group’s evolutionary and ecological success and is a determining factor to take into account for biogeographic studies(Wagner and Liebherr 1992;Peeters and Ito 2001;Helms 2018).展开更多
Background: Prematurely-born individuals tend to exhibit higher resting oxidative stress, although evidence suggests they may be more resistant to acute hypoxia-induced redox balance alterations. We aimed to investiga...Background: Prematurely-born individuals tend to exhibit higher resting oxidative stress, although evidence suggests they may be more resistant to acute hypoxia-induced redox balance alterations. We aimed to investigate the redox balance changes across a 3-day hypobaric hypoxic exposure at 3375 m in healthy adults born preterm(gestational age ≤ 32 weeks) and their term-born(gestational age ≥ 38 weeks)counterparts.Methods: Resting venous blood was obtained in normoxia(prior to altitude exposure), immediately upon arrival to altitude, and the following 3mornings. Antioxidant(superoxide dismutase(SOD), catalase, glutathione peroxidase(GPx), and ferric reducing antioxidant power(FRAP)),pro-oxidant(xanthine oxidase(XO) and myeloperoxidase(MPO)) enzyme activity, oxidative stress markers(advanced oxidation protein product(AOPP) and malondialdehyde(MDA)), nitric oxide(NO) metabolites(nitrites, nitrates, and total nitrite and nitrate(NOx)), and nitrotyrosine were measured in plasma.Results: SOD increased only in the preterm group(p < 0.05). Catalase increased at arrival in preterm group(p < 0.05). XO activity increased at Day 3 for the preterm group, while it increased acutely(arrival and Day 1) in control group. MPO increased in both groups throughout the3 days(p < 0.05). AOPP only increased at arrival in the preterm(p < 0.05) whereas it decreased at arrival up to Day 3(p < 0.05) for control.MDA decreased in control group from arrival onward. Nitrotyrosine decreased in both groups(p < 0.05). Nitrites increased on Day 3(p < 0.05)in control group and decreased on Day 1(p < 0.05) in preterm group.Conclusion: These data indicate that antioxidant enzymes seem to increase immediately upon hypoxic exposure in preterm adults. Conversely, the blunted pro-oxidant enzyme response to prolonged hypoxia exposure suggests that these enzymes may be less sensitive in preterm individuals.These findings lend further support to the potential hypoxic preconditioning effect of preterm birth.展开更多
Hypersonic magnetohydrodynamic(MHD)control effectively enhances the aerothermal environment of aerospace vehicles,demonstrating considerable potential in plasma flow regulation and aerodynamic optimiza-tion.As aerospa...Hypersonic magnetohydrodynamic(MHD)control effectively enhances the aerothermal environment of aerospace vehicles,demonstrating considerable potential in plasma flow regulation and aerodynamic optimiza-tion.As aerospace vehicles progress toward mid-low-altitude hypersonic regimes,their external aerothermal conditions become increasingly severe.This study addresses the challenges of complex aerodynamic force/heat environments and the difficulties in MHD control numerical simulations for hypersonic vehicles at mid-low al-titudes.On the basis of the perfect gas model and the low magnetic Reynolds number assumption,we conduct numerical simulations of MHD control under mid-low altitudes,high-Mach-number conditions.The findings reveal the following:(1)the low magnetic Reynolds number assumption is valid and computationally accurate,as corroborated by a comparative analysis with the literature;(2)in the mid-low altitude hypersonic regime,magnetic fields significantly suppress the shock standoffdistance and reduce the surface heat flux.Both the mag-netically controlled shock wave and the thermal protection exhibit nonlinear variations with the Mach number,increasing and then decreasing as the Mach number increases.The optimal Mach number for shock wave control is 13,whereas optimal thermal protection is achieved at Mach 15.At an altitude of 40 km,the optimal magne-tohydrodynamic Mach range spans 13-17,achieving a maximum heat flux attenuation of 28.81%.Additionally,the effects of magnetic shock wave control correlate approximately exponentially with altitude within certain parameters,whereas the efficacy of thermal protection behaves linearly with altitude variations.展开更多
[Objectives]To analyze the differences in medicinal component contents of Magnolia officinalis across different altitude gradients and explore their causes.[Methods]In this experiment,M.officinalis trees aged 15-20 ye...[Objectives]To analyze the differences in medicinal component contents of Magnolia officinalis across different altitude gradients and explore their causes.[Methods]In this experiment,M.officinalis trees aged 15-20 years growing at four altitudes(1301,1444,1573,and 1643 m)were selected as experimental materials.Leaf traits,soil physicochemical properties,and medicinal component contents were investigated,and the relationships among leaf traits,soil physicochemical properties,and medicinal components were analyzed.[Results]With increasing altitude,the specific leaf area(SLA)of M.officinalis significantly increased,while stomatal density,vein density,leaf thickness,and mesophyll tissue thickness decreased.Soil total nitrogen(TN),total phosphorus(TP),total potassium(TK),available nitrogen(AN),and organic matter contents(OM)decreased significantly with altitude,whereas available potassium(AK)showed the opposite trend.The contents of medicinal components magnolol and honokiol in M.officinalis also significantly decreased with altitude.Correlation analysis revealed that,in addition to altitude,soil physicochemical properties(pH,TP,OM)and leaf traits(leaf thickness,palisade tissue thickness,SLA)were significantly correlated with magnolol and honokiol contents.[Conclusions]M.officinalis at lower altitudes exhibited better growth and higher magnolol and honokiol contents,which may be attributed to higher soil nutrient availability in low-altitude regions.This study provides guidance for selecting cultivation sites and optimizing planting patterns for M.officinalis.展开更多
Thanks to solid archaeological work over recent years,a series of breakthroughs have been achieved in the study of the history of the Xizang Autonomous Region in Paleolithic,Neolithic and Metal Ages.
The innovative study by Zhang et al published in the World Journal of Cardiology focused on predicting 30-day mortality in patients with acute myocardial infarction complicated by ventricular septal rupture at high al...The innovative study by Zhang et al published in the World Journal of Cardiology focused on predicting 30-day mortality in patients with acute myocardial infarction complicated by ventricular septal rupture at high altitudes.Based on a retrospective analysis of 48 patients from Yunnan Province,China,the authors identified four independent predictors of mortality:Age;Elevated uric acid levels;Interleukin-6 and decreased hemoglobin.Integrating these factors into a nomogram demonstrated high predictive accuracy(area under the curve=0.939).This model addressed the critical challenge of risk stratification in the resource-limited settings typical of high-altitude areas.This editorial underscored the practical value of the nomogram for timely identification of candidates for intensive therapy and surgical intervention while emphasizing the need for model validation in multicenter cohorts to optimize the management of these patients.展开更多
1.Opportunities for electric motor drives in the low-altitude economy The implementation plan for the innovative application of general aviation equipment(2024–2030)outlines that by 2027,new general aviation equipmen...1.Opportunities for electric motor drives in the low-altitude economy The implementation plan for the innovative application of general aviation equipment(2024–2030)outlines that by 2027,new general aviation equipment will achieve commercial applications in urban air transport,logistics distribution and emergency rescue.展开更多
Unmanned aerial vehicle light detection and ranging(UAV–LiDAR)is a new method for collecting understory terrain data.The high estimation accuracy of understory terrain is crucial for accurate tree height measurement ...Unmanned aerial vehicle light detection and ranging(UAV–LiDAR)is a new method for collecting understory terrain data.The high estimation accuracy of understory terrain is crucial for accurate tree height measurement and forest resource surveys.The UAV–LiDAR flight altitude and forest canopy cover significantly impact the accuracy of understory terrain estimation.However,since no research examined their combined effects,we aimed to investigate this relationship.This will help optimize UAV–LiDAR flight parameters for understory terrain estimation and forest surveys across various canopy cover.This study analyzed the impacts of three flight altitudes and three canopy cover on the estimation accuracy of understory terrain.The results showed that when canopy cover exceeded a specific value,UAV–LiDAR flight altitudes significantly affected understory terrain estimation.Given a forest canopy cover,the reduction in ground point coverage increased significantly as the flight altitude increased;given a flight altitude,the higher the canopy cover,the more significant the reduction in ground point coverage.In forests with a canopy cover≥0.9,there were substantial differences in the accuracies of understory digital elevation models(DEMs)generated using UAV–LiDAR at different flight altitudes.For forests with a canopy cover<0.9,the mean absolute error(MAE)of understory DEMs from UAV–LiDAR at different flight altitudes was≤0.17 m and the root mean square error(RMSE)was≤0.24 m.However,for forests with a canopy cover≥0.9,the UAV–LiDAR flight altitude significantly affected the accuracy of understory DEMs.At the same flight altitude,the MAE and RMSE of the estimated elevation for forests with a canopy cover≥0.9 were approximately twice those of the estimated elevation for forests with a canopy cover<0.9.In forests with low canopy cover,it is possible to improve data collection efficiency by selecting a higher flight altitude.However,UAV–LiDAR flight altitudes significantly affected understory terrain estimation in forests with high canopy cover,it is essential to adopt terrain-following flight modes,reduce flight altitudes,and maintain a consistent flight altitude during longterm monitoring in high canopy cover forests.展开更多
Ischemic stroke is the leading cause of death in the Chinese population.The incidence of cerebral infarction is higher in high-altitude regions,particularly those above 3,500 m,than in populations residing at lower al...Ischemic stroke is the leading cause of death in the Chinese population.The incidence of cerebral infarction is higher in high-altitude regions,particularly those above 3,500 m,than in populations residing at lower altitudes[1].There are various speculations regarding the mechanisms behind this phenomenon,one of which is that the low oxygen content and cold climate at high altitudes may increase the occurrence of vascular diseases[2].The multifactorial effect of high-altitude environments on residential populations makes it challenging for researchers to determine the specific pathways through which these diseases occur.展开更多
With the theme of“new infrastructure construction in airspace with standards as the foundation-Driving the high-quality development of the low-altitude economy”,a sub-forum brought together representatives from gove...With the theme of“new infrastructure construction in airspace with standards as the foundation-Driving the high-quality development of the low-altitude economy”,a sub-forum brought together representatives from government departments,research institutes,universities,and enterprises to probe into the key role of standardization in the development of the low-altitude economy.展开更多
Low-altitude economy opens up a completely new aerial space for economic growth by enabling brand new services such as fast logistics delivery,timely emergency rescue,and wide-area,high-definition environmental monito...Low-altitude economy opens up a completely new aerial space for economic growth by enabling brand new services such as fast logistics delivery,timely emergency rescue,and wide-area,high-definition environmental monitoring.This new space has many distinct features and therefore faces many new challenges compared with ground-and high-altitude-based information infrastructures.As a result,the rapid and mass development of unmanned aerial vehicles(UAVs)in low-altitude space will inevitably necessitate research on providing ultra-reliable,low-latency,high-capacity.展开更多
Enhancing the ignition system performance of turbo engines is crucial,with a focus on rapidly and reliably igniting the entire combustor in low-temperature,low-pressure,high-speed inlet flow conditions.This challenge ...Enhancing the ignition system performance of turbo engines is crucial,with a focus on rapidly and reliably igniting the entire combustor in low-temperature,low-pressure,high-speed inlet flow conditions.This challenge has garnered international attention.To address the issue of reliable ignition in the combustors of advanced propulsion system,this paper proposes a Multichannel Jet Enhanced Plasma Igniter(MJEPI) and conducts comparative experimental studies with the conventional spark igniter in a component-level dual-dome swirl combustor.The ignition limit in the combustor is obtained and the ignition processes are recorded.Experimental results demonstrate that the MJEPI significantly improves the ignition performance at high altitude.Specifically,at 0 km and 6 km for ground start-up,ignition limit is extended by 36% and 29%,respectively.At 6 km and 12 km for high-altitude relight,ignition limit is extended by 32% and 21%,respectively.The maximum ignition height is increased by 2.3 km,as determined by the global equivalence ratio of 1.The primary reason for these improvements is attributed to the larger initial flame kernel with greater penetration depth generated by MJEPI,which enables it to withstand more sever conditions such as low temperature,low pressure,and poor kerosene spray quality at elevated altitudes.展开更多
As there are numerous challenges to the global industrial and supply chains,the China International Supply Chain Expo(hereinafter referred to as the“CISCE”)hosted by the China Council for the Promotion of Internatio...As there are numerous challenges to the global industrial and supply chains,the China International Supply Chain Expo(hereinafter referred to as the“CISCE”)hosted by the China Council for the Promotion of International Trade(CCPIT),has been playing a unique role as a“stabilizer”for international cooperation,an“accelerator”for economic development,and a“booster”for future transformation.展开更多
With the rapid development of low altitude economic industry,low altitude adhoc network technology has been getting more and more intensive attention.In the adhoc network protocol designed in this paper,the convolutio...With the rapid development of low altitude economic industry,low altitude adhoc network technology has been getting more and more intensive attention.In the adhoc network protocol designed in this paper,the convolutional code used is(3,1,7),and the design of a low power Viterbi decoder adapted to multi-rate variations is proposed.In the traditional Viterbi decoding method,the high complexity of path metric(PM)accumulation and Euclidean distance computation leads to the problems of low efficiency and large storage resources in the decoder.In this paper,an improved add compare select(ACS)algorithm,a generalized formula for branch metric(BM)based on Manhattan distance,and a method to reduce the accumulated PM for different Viterbi decoders are put forward.A simulation environment based on Vivado and Matlab to verify the accuracy and effectiveness of the proposed Viterbi decoder is also established.The experimental results show that the total power consumption is reduced by 15.58%while the decoding accuracy of the Viterbi decoder is guaranteed,which meets the design requirements of a low power Viterbi decoder.展开更多
Propelled by the synergy of policy,technology,and market demand,the low-altitude economy has emerged as a powerful driver of high-quality development in China.This burgeoning sector is reshaping traditional industries...Propelled by the synergy of policy,technology,and market demand,the low-altitude economy has emerged as a powerful driver of high-quality development in China.This burgeoning sector is reshaping traditional industries while forging new strategic pathways for China to excel in the global competitive arena.展开更多
As an emerging industry catering to diverse needs across commercial,industrial,civil,and military fields,the low-altitude economy has the potential to transform industries such as logistics,transportation,tourism,heal...As an emerging industry catering to diverse needs across commercial,industrial,civil,and military fields,the low-altitude economy has the potential to transform industries such as logistics,transportation,tourism,health care,agriculture,and infrastructure.展开更多
Imagine hiring a low-altitude aircraft from your office to the airport to avoid road traffic congestion,flying across the Yangtze River in an air taxi,or sitting by the Great Wall and enjoying a cup of cappuccino deli...Imagine hiring a low-altitude aircraft from your office to the airport to avoid road traffic congestion,flying across the Yangtze River in an air taxi,or sitting by the Great Wall and enjoying a cup of cappuccino delivered by a drone...All these are gradually becoming a reality in China as the low-altitude economy rapidly advances.展开更多
基金Supported by Army Logistics Department Health Bureau Project,No.QJGYXYJZX-012.
文摘BACKGROUND Due to the dry and cold climate,the obvious temperature difference between day and night,and the low oxygen content of the air in the plateau area,people are prone to upper respiratory tract diseases,and often the condition is prolonged,and the patients are prone to anxiety and uneasiness,which may be related to the harshness of the plateau environment,somatic discomfort due to the lack of oxygen,anxiety about the disease,and other factors.AIM To investigate the effects of cognitive behavioral therapy(CBT)on anxiety,sleep disorders,and hypoxia tolerance in patients with high-altitude respiratory diseases.METHODS A total of 2337 patients with high-altitude-related respiratory diseases treated at our hospital between November 2023 and January 2024 were selected as the study subjects.The subjects’pre-high-altitude residential altitude was approximately 1700 meters.They were divided into two groups.Both groups were given symptomatic treatment,and the control group implemented conventional nursing intervention,while the research group simultaneously conducted CBT intervention;assessed the degree of health knowledge of the two groups,and applied the Hamilton Anxiety Scale and the Pittsburgh Sleep Quality Index to assess the anxiety and sleep quality of the patients before and after the intervention,respectively.It also observed the length and efficiency of sleep,and detected the level of serum hypoxia inducible factor-1α,erythropoietin(EPO)and clinical intervention before and after intervention.EPO levels,and investigated satisfaction with the clinical intervention.RESULTS The rate of excellent health knowledge in the intervention group was 93.64%,which was higher than that in the control group(74.23%;P<0.05).Before the intervention,there was no significant difference in Hamilton Anxiety Scale and Pittsburgh Sleep Quality Index scores between the two groups(P>0.05),and after the intervention,the scores of the study group were significantly lower than those of the control group(P<0.05).There was no significant difference in sleep duration and sleep efficiency between the groups before the intervention(P>0.05),and after the intervention,the scores of the study group were significantly larger than those of the control group(P<0.05).There was no significant difference in serum hypoxia inducible factor-1αand EPO between the two groups before intervention(P>0.05),and both research groups were significantly lower than the control group after intervention(P<0.05).According to the questionnaire survey,the intervention satisfaction of the study group was 95.53%,which was higher than that of the control group(80.14%;P<0.05).CONCLUSION The CBT intervention in the treatment of patients with high-altitude-related respiratory diseases helps improve patients'health knowledge,relieve anxiety,improve sleep quality and hypoxia tolerance,and improve nursing satisfaction.
基金supported by the National Natural Science Foundation of China (32021005, 32272332)the Fundamental Research Funds for the Central Universities (JUSRP622020, JUSRP51501)+1 种基金the Program of Collaborative Innovation Centre of Food Safety and Quality Control in Jiangsu ProvinceWuxi Science and Technology Development Fund Projects (Y20232022)
文摘The number of people travelling to high-altitude areas or participating in mountain sports is increasing.For individuals visiting such terrains for the first time,the lack of adaptation to the hypobaric hypoxic environment can lead to the deterioration of gastrointestinal function and barriers.In more severe cases,this lack of acclimatisation may lead to acute high-altitude illness.At present,the prevention and treatment of these issues primarily revolve around strategies such as descending to lower altitudes,oxygen supplementation,and medication.However,the available intervention measures to prevent health problems resulting from high-altitude environments remain limited.In this review,we discuss common altitude-related illnesses,including gastrointestinal problems.Moreover,we explore the potential of commonly used medications and dietary supplements in alleviating altitude-related issues.This review can provide a basis for future research on modulating the gut microbiota for mitigating high-altitude illness.
基金financially supported by National Natural Science Foundation of China(Grant Nos.52378401,52278504)the Fundamental Research Funds for the Central Universities(Grant No.30922010918)。
文摘Traffic engineering such as tunnels in various altitudinal gradient zone are at risk of accidental explosion,which can damage personnel and equipment.Accurate prediction of the distribution pattern of explosive loads and shock wave propagation process in semi-enclosed structures at various altitude environment is key research focus in the fields of explosion shock and fluid dynamics.The effect of altitude on the propagation of shock waves in tunnels was investigated by conducting explosion test and numerical simulation.Based on the experimental and numerical simulation results,a prediction model for the attenuation of the peak overpressure of tunnel shock waves at different altitudes was established.The results showed that the peak overpressure decreased at the same measurement points in the tunnel entrance under the high altitude condition.In contrast,an increase in altitude accelerated the propagation speed of the shock wave in the tunnel.The average error between the peak shock wave overpressure obtained using the overpressure prediction formula and the measured test data was less than15%,the average error between the propagation velocity of shock waves predicted values and the test data is less than 10%.The method can effectively predict the overpressure attenuation of blast wave in tunnel at various altitudes.
基金funded by the“Departments of Excellence”program of the Italian Ministry for University and Research(MIUR,2018-2022 and MUR,2023-2027).
文摘The ability of queens and males of most ant species to disperse by flight has fundamentally contributed to the group’s evolutionary and ecological success and is a determining factor to take into account for biogeographic studies(Wagner and Liebherr 1992;Peeters and Ito 2001;Helms 2018).
基金funded by the Swiss National Science Foundation(SNSF Grant No.320030L_192073 to GM)the Slovenian Research Agency(ARRS Grant No.N5-0152 to TD).
文摘Background: Prematurely-born individuals tend to exhibit higher resting oxidative stress, although evidence suggests they may be more resistant to acute hypoxia-induced redox balance alterations. We aimed to investigate the redox balance changes across a 3-day hypobaric hypoxic exposure at 3375 m in healthy adults born preterm(gestational age ≤ 32 weeks) and their term-born(gestational age ≥ 38 weeks)counterparts.Methods: Resting venous blood was obtained in normoxia(prior to altitude exposure), immediately upon arrival to altitude, and the following 3mornings. Antioxidant(superoxide dismutase(SOD), catalase, glutathione peroxidase(GPx), and ferric reducing antioxidant power(FRAP)),pro-oxidant(xanthine oxidase(XO) and myeloperoxidase(MPO)) enzyme activity, oxidative stress markers(advanced oxidation protein product(AOPP) and malondialdehyde(MDA)), nitric oxide(NO) metabolites(nitrites, nitrates, and total nitrite and nitrate(NOx)), and nitrotyrosine were measured in plasma.Results: SOD increased only in the preterm group(p < 0.05). Catalase increased at arrival in preterm group(p < 0.05). XO activity increased at Day 3 for the preterm group, while it increased acutely(arrival and Day 1) in control group. MPO increased in both groups throughout the3 days(p < 0.05). AOPP only increased at arrival in the preterm(p < 0.05) whereas it decreased at arrival up to Day 3(p < 0.05) for control.MDA decreased in control group from arrival onward. Nitrotyrosine decreased in both groups(p < 0.05). Nitrites increased on Day 3(p < 0.05)in control group and decreased on Day 1(p < 0.05) in preterm group.Conclusion: These data indicate that antioxidant enzymes seem to increase immediately upon hypoxic exposure in preterm adults. Conversely, the blunted pro-oxidant enzyme response to prolonged hypoxia exposure suggests that these enzymes may be less sensitive in preterm individuals.These findings lend further support to the potential hypoxic preconditioning effect of preterm birth.
基金the results of the research project funded by National Numerical Wind Tunnel Project of China.
文摘Hypersonic magnetohydrodynamic(MHD)control effectively enhances the aerothermal environment of aerospace vehicles,demonstrating considerable potential in plasma flow regulation and aerodynamic optimiza-tion.As aerospace vehicles progress toward mid-low-altitude hypersonic regimes,their external aerothermal conditions become increasingly severe.This study addresses the challenges of complex aerodynamic force/heat environments and the difficulties in MHD control numerical simulations for hypersonic vehicles at mid-low al-titudes.On the basis of the perfect gas model and the low magnetic Reynolds number assumption,we conduct numerical simulations of MHD control under mid-low altitudes,high-Mach-number conditions.The findings reveal the following:(1)the low magnetic Reynolds number assumption is valid and computationally accurate,as corroborated by a comparative analysis with the literature;(2)in the mid-low altitude hypersonic regime,magnetic fields significantly suppress the shock standoffdistance and reduce the surface heat flux.Both the mag-netically controlled shock wave and the thermal protection exhibit nonlinear variations with the Mach number,increasing and then decreasing as the Mach number increases.The optimal Mach number for shock wave control is 13,whereas optimal thermal protection is achieved at Mach 15.At an altitude of 40 km,the optimal magne-tohydrodynamic Mach range spans 13-17,achieving a maximum heat flux attenuation of 28.81%.Additionally,the effects of magnetic shock wave control correlate approximately exponentially with altitude within certain parameters,whereas the efficacy of thermal protection behaves linearly with altitude variations.
基金Supported by National Key Research and Development Program of China in 2018(2018YFC1708005)the Southwest Minzu University Research Startup Funds(RQD2023020).
文摘[Objectives]To analyze the differences in medicinal component contents of Magnolia officinalis across different altitude gradients and explore their causes.[Methods]In this experiment,M.officinalis trees aged 15-20 years growing at four altitudes(1301,1444,1573,and 1643 m)were selected as experimental materials.Leaf traits,soil physicochemical properties,and medicinal component contents were investigated,and the relationships among leaf traits,soil physicochemical properties,and medicinal components were analyzed.[Results]With increasing altitude,the specific leaf area(SLA)of M.officinalis significantly increased,while stomatal density,vein density,leaf thickness,and mesophyll tissue thickness decreased.Soil total nitrogen(TN),total phosphorus(TP),total potassium(TK),available nitrogen(AN),and organic matter contents(OM)decreased significantly with altitude,whereas available potassium(AK)showed the opposite trend.The contents of medicinal components magnolol and honokiol in M.officinalis also significantly decreased with altitude.Correlation analysis revealed that,in addition to altitude,soil physicochemical properties(pH,TP,OM)and leaf traits(leaf thickness,palisade tissue thickness,SLA)were significantly correlated with magnolol and honokiol contents.[Conclusions]M.officinalis at lower altitudes exhibited better growth and higher magnolol and honokiol contents,which may be attributed to higher soil nutrient availability in low-altitude regions.This study provides guidance for selecting cultivation sites and optimizing planting patterns for M.officinalis.
文摘Thanks to solid archaeological work over recent years,a series of breakthroughs have been achieved in the study of the history of the Xizang Autonomous Region in Paleolithic,Neolithic and Metal Ages.
文摘The innovative study by Zhang et al published in the World Journal of Cardiology focused on predicting 30-day mortality in patients with acute myocardial infarction complicated by ventricular septal rupture at high altitudes.Based on a retrospective analysis of 48 patients from Yunnan Province,China,the authors identified four independent predictors of mortality:Age;Elevated uric acid levels;Interleukin-6 and decreased hemoglobin.Integrating these factors into a nomogram demonstrated high predictive accuracy(area under the curve=0.939).This model addressed the critical challenge of risk stratification in the resource-limited settings typical of high-altitude areas.This editorial underscored the practical value of the nomogram for timely identification of candidates for intensive therapy and surgical intervention while emphasizing the need for model validation in multicenter cohorts to optimize the management of these patients.
基金supported by the National Natural Science Foundation of China(No.52407064)。
文摘1.Opportunities for electric motor drives in the low-altitude economy The implementation plan for the innovative application of general aviation equipment(2024–2030)outlines that by 2027,new general aviation equipment will achieve commercial applications in urban air transport,logistics distribution and emergency rescue.
基金supported by the National Natural Science Foundation of China(No.32271876)the Research on Key Technologies of Intelligent Monitoring and Carbon Sink Metering of Forest Resources in Fujian Province(No.2022FKJ03)the Science and Technology Innovation Project of Fujian Agriculture and Forestry University(No.KFB23172A,KFB23173A).
文摘Unmanned aerial vehicle light detection and ranging(UAV–LiDAR)is a new method for collecting understory terrain data.The high estimation accuracy of understory terrain is crucial for accurate tree height measurement and forest resource surveys.The UAV–LiDAR flight altitude and forest canopy cover significantly impact the accuracy of understory terrain estimation.However,since no research examined their combined effects,we aimed to investigate this relationship.This will help optimize UAV–LiDAR flight parameters for understory terrain estimation and forest surveys across various canopy cover.This study analyzed the impacts of three flight altitudes and three canopy cover on the estimation accuracy of understory terrain.The results showed that when canopy cover exceeded a specific value,UAV–LiDAR flight altitudes significantly affected understory terrain estimation.Given a forest canopy cover,the reduction in ground point coverage increased significantly as the flight altitude increased;given a flight altitude,the higher the canopy cover,the more significant the reduction in ground point coverage.In forests with a canopy cover≥0.9,there were substantial differences in the accuracies of understory digital elevation models(DEMs)generated using UAV–LiDAR at different flight altitudes.For forests with a canopy cover<0.9,the mean absolute error(MAE)of understory DEMs from UAV–LiDAR at different flight altitudes was≤0.17 m and the root mean square error(RMSE)was≤0.24 m.However,for forests with a canopy cover≥0.9,the UAV–LiDAR flight altitude significantly affected the accuracy of understory DEMs.At the same flight altitude,the MAE and RMSE of the estimated elevation for forests with a canopy cover≥0.9 were approximately twice those of the estimated elevation for forests with a canopy cover<0.9.In forests with low canopy cover,it is possible to improve data collection efficiency by selecting a higher flight altitude.However,UAV–LiDAR flight altitudes significantly affected understory terrain estimation in forests with high canopy cover,it is essential to adopt terrain-following flight modes,reduce flight altitudes,and maintain a consistent flight altitude during longterm monitoring in high canopy cover forests.
基金supported by the National Natural Science Foundation of Chongqing,China(CSTB2022NSCQ-MSX1100)National Natural Science Foundation of China(grant no.82101499).
文摘Ischemic stroke is the leading cause of death in the Chinese population.The incidence of cerebral infarction is higher in high-altitude regions,particularly those above 3,500 m,than in populations residing at lower altitudes[1].There are various speculations regarding the mechanisms behind this phenomenon,one of which is that the low oxygen content and cold climate at high altitudes may increase the occurrence of vascular diseases[2].The multifactorial effect of high-altitude environments on residential populations makes it challenging for researchers to determine the specific pathways through which these diseases occur.
文摘With the theme of“new infrastructure construction in airspace with standards as the foundation-Driving the high-quality development of the low-altitude economy”,a sub-forum brought together representatives from government departments,research institutes,universities,and enterprises to probe into the key role of standardization in the development of the low-altitude economy.
文摘Low-altitude economy opens up a completely new aerial space for economic growth by enabling brand new services such as fast logistics delivery,timely emergency rescue,and wide-area,high-definition environmental monitoring.This new space has many distinct features and therefore faces many new challenges compared with ground-and high-altitude-based information infrastructures.As a result,the rapid and mass development of unmanned aerial vehicles(UAVs)in low-altitude space will inevitably necessitate research on providing ultra-reliable,low-latency,high-capacity.
基金supported by the Science Center for Gas Turbine Project, China (No. P2022-B-Ⅱ-018-001)。
文摘Enhancing the ignition system performance of turbo engines is crucial,with a focus on rapidly and reliably igniting the entire combustor in low-temperature,low-pressure,high-speed inlet flow conditions.This challenge has garnered international attention.To address the issue of reliable ignition in the combustors of advanced propulsion system,this paper proposes a Multichannel Jet Enhanced Plasma Igniter(MJEPI) and conducts comparative experimental studies with the conventional spark igniter in a component-level dual-dome swirl combustor.The ignition limit in the combustor is obtained and the ignition processes are recorded.Experimental results demonstrate that the MJEPI significantly improves the ignition performance at high altitude.Specifically,at 0 km and 6 km for ground start-up,ignition limit is extended by 36% and 29%,respectively.At 6 km and 12 km for high-altitude relight,ignition limit is extended by 32% and 21%,respectively.The maximum ignition height is increased by 2.3 km,as determined by the global equivalence ratio of 1.The primary reason for these improvements is attributed to the larger initial flame kernel with greater penetration depth generated by MJEPI,which enables it to withstand more sever conditions such as low temperature,low pressure,and poor kerosene spray quality at elevated altitudes.
文摘As there are numerous challenges to the global industrial and supply chains,the China International Supply Chain Expo(hereinafter referred to as the“CISCE”)hosted by the China Council for the Promotion of International Trade(CCPIT),has been playing a unique role as a“stabilizer”for international cooperation,an“accelerator”for economic development,and a“booster”for future transformation.
基金Supported by the National Natural Science Foundation of China(No.62103257).
文摘With the rapid development of low altitude economic industry,low altitude adhoc network technology has been getting more and more intensive attention.In the adhoc network protocol designed in this paper,the convolutional code used is(3,1,7),and the design of a low power Viterbi decoder adapted to multi-rate variations is proposed.In the traditional Viterbi decoding method,the high complexity of path metric(PM)accumulation and Euclidean distance computation leads to the problems of low efficiency and large storage resources in the decoder.In this paper,an improved add compare select(ACS)algorithm,a generalized formula for branch metric(BM)based on Manhattan distance,and a method to reduce the accumulated PM for different Viterbi decoders are put forward.A simulation environment based on Vivado and Matlab to verify the accuracy and effectiveness of the proposed Viterbi decoder is also established.The experimental results show that the total power consumption is reduced by 15.58%while the decoding accuracy of the Viterbi decoder is guaranteed,which meets the design requirements of a low power Viterbi decoder.
文摘Propelled by the synergy of policy,technology,and market demand,the low-altitude economy has emerged as a powerful driver of high-quality development in China.This burgeoning sector is reshaping traditional industries while forging new strategic pathways for China to excel in the global competitive arena.
文摘As an emerging industry catering to diverse needs across commercial,industrial,civil,and military fields,the low-altitude economy has the potential to transform industries such as logistics,transportation,tourism,health care,agriculture,and infrastructure.
文摘Imagine hiring a low-altitude aircraft from your office to the airport to avoid road traffic congestion,flying across the Yangtze River in an air taxi,or sitting by the Great Wall and enjoying a cup of cappuccino delivered by a drone...All these are gradually becoming a reality in China as the low-altitude economy rapidly advances.
