Zeolite Beta containing ultra-small CoO particles was synthesized from a one-step hydrothermal process. The synthesis route involves the pre-mixture of hydrofluoric acid with tetraethylammo- nium hydroxide （in a mola...Zeolite Beta containing ultra-small CoO particles was synthesized from a one-step hydrothermal process. The synthesis route involves the pre-mixture of hydrofluoric acid with tetraethylammo- nium hydroxide （in a molar ratio of 1.3-1.5：1） before the addition of a silicon and cobalt source.Investigations by scanning electron microscopy, X-ray diffraction, UV-Vi s spectroscopy, X-ray pho-toelectron spectroscopy, H 2 -temperature-programmed reduct i on and transmi ssi on el ectron mi -croscopy confirm the presence of ultra-small CoO particles in the zeolite Beta structure. The ul-tra-small CoO particles in zeolite Beta present high stability against both oxidation and reduction atmospheres at high temperatures. The catalytic performance of the CoO-containing zeolite Beta catalysts was compared with other Co-containing zeolites by evaluating ethylbenzene oxidation reactivity. The CoO-containing zeolite Beta exhibits high ethylbenzene conversion and high selectiv-ity to acetophenone and 1-phenylethanol. The high activity of this catalyst system can be attributed to the high dispersion of the ultra-small CoO particles in the Beta structure.展开更多
In this paper,energy loss of alpha particles in different vacuum levels is studied experimentally and via theoretical analysis.A better understanding of energy loss of a particle in vacuum will help detect more exact ...In this paper,energy loss of alpha particles in different vacuum levels is studied experimentally and via theoretical analysis.A better understanding of energy loss of a particle in vacuum will help detect more exact numbers of alpha particles.Two ^(239)Pu sources are used to measure the energy loss of a particle crossing different vacuum levels (different air pressures).The experimental data are obtained from an instrument-PAM-100 developed by authors. The experimental results have shown that increasing vacuum levels will lead to more alpha residual energy but less energy loss.When the vacuum level reaches 0.04 MPa,alpha particles(^(239)Pu,5.115 MeV)will lose the energy of about 0.175 MeV with traversing 5 mm distance.Theoretical calculations have shown a good agreement with experimental results.This implies that the instrument has a high accuracy and could be applied in field work.展开更多
Alpha-lipoic acid-loaded lipid nanoparticles(ALA-LNs) were prepared by high pressure homogenization method.The influences of storage conditions such as time and temperature on the physical and chemical storage stabili...Alpha-lipoic acid-loaded lipid nanoparticles(ALA-LNs) were prepared by high pressure homogenization method.The influences of storage conditions such as time and temperature on the physical and chemical storage stability of ALA-LNs were studied in details.The stability was evaluated by particle size and polydispersity index,morphology of ALA-LNs,and capacity of ALA loading.The dilution and pH stability of ALA-LNs suspensions were also studied.After three months storage,the mean size of ALA-LNs at 4 and 40 ℃ was increased by 2.68% and 3.62% compared with the original size,respectively.ALA-LNs stored at 40 ℃ had ellipsoid shape and the mean size was about 152 nm(SD=23.6).The loading capacity of ALA at 40 ℃ was much higher than those stored at other two temperatures.The good dilution and pH stability were also demonstrated.The sample had good fluidity even at 4 ℃.展开更多
Objective： To investigate the impact of beta-elemene injection on the growth and alpha-tubule of human hepatocarcinoma HepG2 cells. Methods： Cell proliferation was assessed by MTT assay. Cell cycle distribution was ...Objective： To investigate the impact of beta-elemene injection on the growth and alpha-tubule of human hepatocarcinoma HepG2 cells. Methods： Cell proliferation was assessed by MTT assay. Cell cycle distribution was detected by flow cytometry （FCM）. The mRNA expression of alpha-tubulin was measured by RT-PCR. Western blot analysis was used to determine protein expression of alpha-tubulin and the polymerization of tubulin. Results： Beta-elemene injection inhibited HepG2 cells proliferation in a dose- and time-dependent manner; FCM analysis indicated beta-elemene injection induced cell cycle arrested at S phase. RT-PCR and western- blot analysis showed that beta-elemene injection down-regulated alpha-tublin at both mRNA and protein levels, presenting a dose-dependent manner. Moreover, beta-elemene injection reduced the polymerization of microtubules in a dose-dependent manner. Conclusions： Beta-elemene injection can inhibit the proliferation of hepatoma HepG2 cells and induce cell apoptosis, the mechanism might be partly related to the down-regulation of alpha-tubulin and inhibition of microtubular polymerization.展开更多
The alpha–beta filter algorithm has been widely researched for various applications,for example,navigation and target tracking systems.To improve the dynamic performance of the alpha–beta filter algorithm,a new pred...The alpha–beta filter algorithm has been widely researched for various applications,for example,navigation and target tracking systems.To improve the dynamic performance of the alpha–beta filter algorithm,a new prediction learning model is proposed in this study.The proposed model has two main components:(1)the alpha–beta filter algorithm is the main prediction module,and(2)the learning module is a feedforward artificial neural network(FF‐ANN).Furthermore,the model uses two inputs,temperature sensor and humidity sensor data,and a prediction algorithm is used to predict actual sensor readings from noisy sensor readings.Using the novel proposed technique,prediction accuracy is significantly improved while adding the feed‐forward backpropagation neural network,and also reduces the root mean square error(RMSE)and mean absolute error(MAE).We carried out different experiments with different experimental setups.The proposed model performance was evaluated with the traditional alpha–beta filter algorithm and other algorithms such as the Kalman filter.A higher prediction accuracy was achieved,and the MAE and RMSE were 35.1%–38.2%respectively.The final proposed model results show increased performance when compared to traditional methods.展开更多
Au/Ni/n-type 4H-SiC Schottky alpha particle detectors are fabricated and annealed at temperatures between 400℃ and 700 ℃ to investigate the effects of thermal stability of the Schottky contact on the structural and ...Au/Ni/n-type 4H-SiC Schottky alpha particle detectors are fabricated and annealed at temperatures between 400℃ and 700 ℃ to investigate the effects of thermal stability of the Schottky contact on the structural and electrical properties of the detectors. At the annealing temperature of 500 ℃, the two nickel silicides （i.e., Ni31Sil2 and Ni2Si） are formed at the interface and result in the formation of an inhomogeneous Schottky barrier. By increasing the annealing temperature, the Ni31Sil2 transforms into the more stable Ni2Si. The structural evolution of the Schottky contact directly affects the electrical properties and alpha particle energy resolutions of the detectors. A better energy resolution of 2.60% is obtained for 5.48-MeV alpha particles with the detector after being annealed at 600 ℃. As a result, the Au/Ni/n-type 4H-SiC Schottky detector shows a good performance after thermal treatment at temperatures up to 700℃.展开更多
基金supported by Strategic Priority Research Program of the Chinese Academy of Sciences(XDA07020300)~~
文摘Zeolite Beta containing ultra-small CoO particles was synthesized from a one-step hydrothermal process. The synthesis route involves the pre-mixture of hydrofluoric acid with tetraethylammo- nium hydroxide （in a molar ratio of 1.3-1.5：1） before the addition of a silicon and cobalt source.Investigations by scanning electron microscopy, X-ray diffraction, UV-Vi s spectroscopy, X-ray pho-toelectron spectroscopy, H 2 -temperature-programmed reduct i on and transmi ssi on el ectron mi -croscopy confirm the presence of ultra-small CoO particles in the zeolite Beta structure. The ul-tra-small CoO particles in zeolite Beta present high stability against both oxidation and reduction atmospheres at high temperatures. The catalytic performance of the CoO-containing zeolite Beta catalysts was compared with other Co-containing zeolites by evaluating ethylbenzene oxidation reactivity. The CoO-containing zeolite Beta exhibits high ethylbenzene conversion and high selectiv-ity to acetophenone and 1-phenylethanol. The high activity of this catalyst system can be attributed to the high dispersion of the ultra-small CoO particles in the Beta structure.
基金Supported by the National Natural Science Foundation of China(Grant No.40974065)the National Science Foundation for Distinguished Young Scholars of China(Grant No.41025015)
文摘In this paper,energy loss of alpha particles in different vacuum levels is studied experimentally and via theoretical analysis.A better understanding of energy loss of a particle in vacuum will help detect more exact numbers of alpha particles.Two ^(239)Pu sources are used to measure the energy loss of a particle crossing different vacuum levels (different air pressures).The experimental data are obtained from an instrument-PAM-100 developed by authors. The experimental results have shown that increasing vacuum levels will lead to more alpha residual energy but less energy loss.When the vacuum level reaches 0.04 MPa,alpha particles(^(239)Pu,5.115 MeV)will lose the energy of about 0.175 MeV with traversing 5 mm distance.Theoretical calculations have shown a good agreement with experimental results.This implies that the instrument has a high accuracy and could be applied in field work.
基金Supported by International Scientific Cooperation Project of China (No.2008DFB50060)Suzhou Innovation Funds of High-Tech Enterprise (No.SG0958)
文摘Alpha-lipoic acid-loaded lipid nanoparticles(ALA-LNs) were prepared by high pressure homogenization method.The influences of storage conditions such as time and temperature on the physical and chemical storage stability of ALA-LNs were studied in details.The stability was evaluated by particle size and polydispersity index,morphology of ALA-LNs,and capacity of ALA loading.The dilution and pH stability of ALA-LNs suspensions were also studied.After three months storage,the mean size of ALA-LNs at 4 and 40 ℃ was increased by 2.68% and 3.62% compared with the original size,respectively.ALA-LNs stored at 40 ℃ had ellipsoid shape and the mean size was about 152 nm(SD=23.6).The loading capacity of ALA at 40 ℃ was much higher than those stored at other two temperatures.The good dilution and pH stability were also demonstrated.The sample had good fluidity even at 4 ℃.
基金The General Program of National Natural Science Foundation of China:Research Fund for the mechanism of Arenobufagin space isomer inhibits lymphatic metastasis of mouse hepatocarcinomaThe Project Sponsored by the Scientific Research Foundation for the Returned Overseas Chinese Scholars,State Education MinistrySpecialized Research Fund for the Doctoral Program of Higher Education(NO.20102105120002)
文摘Objective： To investigate the impact of beta-elemene injection on the growth and alpha-tubule of human hepatocarcinoma HepG2 cells. Methods： Cell proliferation was assessed by MTT assay. Cell cycle distribution was detected by flow cytometry （FCM）. The mRNA expression of alpha-tubulin was measured by RT-PCR. Western blot analysis was used to determine protein expression of alpha-tubulin and the polymerization of tubulin. Results： Beta-elemene injection inhibited HepG2 cells proliferation in a dose- and time-dependent manner; FCM analysis indicated beta-elemene injection induced cell cycle arrested at S phase. RT-PCR and western- blot analysis showed that beta-elemene injection down-regulated alpha-tublin at both mRNA and protein levels, presenting a dose-dependent manner. Moreover, beta-elemene injection reduced the polymerization of microtubules in a dose-dependent manner. Conclusions： Beta-elemene injection can inhibit the proliferation of hepatoma HepG2 cells and induce cell apoptosis, the mechanism might be partly related to the down-regulation of alpha-tubulin and inhibition of microtubular polymerization.
基金supported by the Institute of Information&communications Technology Planning&Evaluation(IITP)grant funded by the Korea government(MSIT)(No.2020‐0‐01441,Artificial Intelligence Convergence Research Center(Chungnam National University))“Regional Innovation Strategy(RIS)”through the National Research Foundation of Korea(NRF)funded by the Ministry of Education(MOE)(2021RIS‐004).
文摘The alpha–beta filter algorithm has been widely researched for various applications,for example,navigation and target tracking systems.To improve the dynamic performance of the alpha–beta filter algorithm,a new prediction learning model is proposed in this study.The proposed model has two main components:(1)the alpha–beta filter algorithm is the main prediction module,and(2)the learning module is a feedforward artificial neural network(FF‐ANN).Furthermore,the model uses two inputs,temperature sensor and humidity sensor data,and a prediction algorithm is used to predict actual sensor readings from noisy sensor readings.Using the novel proposed technique,prediction accuracy is significantly improved while adding the feed‐forward backpropagation neural network,and also reduces the root mean square error(RMSE)and mean absolute error(MAE).We carried out different experiments with different experimental setups.The proposed model performance was evaluated with the traditional alpha–beta filter algorithm and other algorithms such as the Kalman filter.A higher prediction accuracy was achieved,and the MAE and RMSE were 35.1%–38.2%respectively.The final proposed model results show increased performance when compared to traditional methods.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.11675198,61574026,and 11405017)the National Key Research and Development Program of China(Grant Nos.2016YFB0400600 and 2016YFB0400601)+1 种基金the Natural Science Foundation of Liaoning Province of China(Grant Nos.201602453 and 201602176)the China Postdoctoral Science Foundation(Grant No.2016M591434)
文摘Au/Ni/n-type 4H-SiC Schottky alpha particle detectors are fabricated and annealed at temperatures between 400℃ and 700 ℃ to investigate the effects of thermal stability of the Schottky contact on the structural and electrical properties of the detectors. At the annealing temperature of 500 ℃, the two nickel silicides （i.e., Ni31Sil2 and Ni2Si） are formed at the interface and result in the formation of an inhomogeneous Schottky barrier. By increasing the annealing temperature, the Ni31Sil2 transforms into the more stable Ni2Si. The structural evolution of the Schottky contact directly affects the electrical properties and alpha particle energy resolutions of the detectors. A better energy resolution of 2.60% is obtained for 5.48-MeV alpha particles with the detector after being annealed at 600 ℃. As a result, the Au/Ni/n-type 4H-SiC Schottky detector shows a good performance after thermal treatment at temperatures up to 700℃.
