Aim: To evaluate the antifertility activity of the methanolic pod extract of Albizzia lebbeck (L.) Benth in male albino rats. Methods: The methanolic pod extract of Albizzia lebbeck was administrated orally for 60 day...Aim: To evaluate the antifertility activity of the methanolic pod extract of Albizzia lebbeck (L.) Benth in male albino rats. Methods: The methanolic pod extract of Albizzia lebbeck was administrated orally for 60 days at 50, 100 and 200 mg·kg-1·day-1 to male albino rats. Sperm motility and density in cauda epididymides were assessed. Biochemical and histological analysis were performed in blood samples and reproductive organs. Results: A. lebbeck pod extract brought about a significant decrease in the weights of testis, seminal vesicles, epdidymis and ventral prostate. The sperm motility and density were significantly reduced. There was a marked reduction in the numbers of primary spermatocytes, secondary spermatocytes and spermatids. The Sertoli cell count as well as its cross sectional surface area were significantly decreased. The Leydig cell nuclear area and the number of mature Leydig celis were also significantly decreased. The protein, glycogen and cholesterol content of the testis, the fructose in the seminal vesicles and protein in the epididymis were significantly decreased. The RBC and WBC counts, haemoglobin, haematocrit and blood sugar were within the normai range. Conclusion: The methanolic extract of A. lebbeck pods causes spermatogenic arrest in male albino rats.展开更多
Albizzia is a leguminous genus belonging to the subfamily Mimosoideae with approximately 150 modern species,widely distributed in the tropical and subtropical regions of Asia,Africa,Australia and America.Among them,17...Albizzia is a leguminous genus belonging to the subfamily Mimosoideae with approximately 150 modern species,widely distributed in the tropical and subtropical regions of Asia,Africa,Australia and America.Among them,17 species are mainly distributed in southern and southwestern China.Abundant fossils of the subfamily Mimosoideae,including leaves,pods,flowers and wood,have been reported from the Cretaceous and Paleogene strata of the Northern Hemisphere.However,Neogene records of Mimosoideae are relatively scarce.In this study,fossil pods and leaves belonging to the genus Aibizzia from the Bangmai Formation of Yunnan,China were described.They were assigned to three species,including Albizzia scalpeUiformis Guo,Li and Xie Emended,Albizzia cf.kalkora(Roxb.)Prain and Albizzia sp.The occurrence of Albizzia fossils from Lincang not only gives important information on the Neogene plant diversity from Yunnan--a worldwide famous biological hotspot--but also provides additional evidence for its phytogeographic history.展开更多
Changes in cellular isoflavone （daidzein and genistein） contents were monitored in root cultures of Albizzia kalkora （Roxb.） Prain after feeding different ratios of NH4^＋/NO3^- and treatment with a biotic elicit...Changes in cellular isoflavone （daidzein and genistein） contents were monitored in root cultures of Albizzia kalkora （Roxb.） Prain after feeding different ratios of NH4^＋/NO3^- and treatment with a biotic elicitor （three strains of Rhizobium sp.）. The NH4^＋/NO3^- ratio appears to be positively correlated with daidzein content in the roots and shows a negative correlation with genistein. Among the three different strains of Rhizobium used, the strain ATCC 15834 caused a 35% increase in daidzein production by infection. In the case of genistein, maximum production （94%） was obtained when cultures were treated on Day 6 by the strains ATCC 15834 and KCTC 1541. The biosynthetic pathway of the two isoflavones apparently reacts differently to the same culture conditions and the same strains of Rhizobium. Therefore, the present data suggest that the production of daidzein and genistein could be modulated by changing the NH4^＋/NO3^- ratio and the application of Rhizobium.展开更多
文摘Aim: To evaluate the antifertility activity of the methanolic pod extract of Albizzia lebbeck (L.) Benth in male albino rats. Methods: The methanolic pod extract of Albizzia lebbeck was administrated orally for 60 days at 50, 100 and 200 mg·kg-1·day-1 to male albino rats. Sperm motility and density in cauda epididymides were assessed. Biochemical and histological analysis were performed in blood samples and reproductive organs. Results: A. lebbeck pod extract brought about a significant decrease in the weights of testis, seminal vesicles, epdidymis and ventral prostate. The sperm motility and density were significantly reduced. There was a marked reduction in the numbers of primary spermatocytes, secondary spermatocytes and spermatids. The Sertoli cell count as well as its cross sectional surface area were significantly decreased. The Leydig cell nuclear area and the number of mature Leydig celis were also significantly decreased. The protein, glycogen and cholesterol content of the testis, the fructose in the seminal vesicles and protein in the epididymis were significantly decreased. The RBC and WBC counts, haemoglobin, haematocrit and blood sugar were within the normai range. Conclusion: The methanolic extract of A. lebbeck pods causes spermatogenic arrest in male albino rats.
基金supported by the National Natural Science Foundation of China(Nos.41172021,41302009)the Foundation of the State Key Laboratory of Palaeobiology and Stratigraphy,Nanjing Institute of Geology and Palaeontology,CAS(No.173126)the Fundamental Research Funds for the Central Universities of China(No.lzujbky-2017-74)
文摘Albizzia is a leguminous genus belonging to the subfamily Mimosoideae with approximately 150 modern species,widely distributed in the tropical and subtropical regions of Asia,Africa,Australia and America.Among them,17 species are mainly distributed in southern and southwestern China.Abundant fossils of the subfamily Mimosoideae,including leaves,pods,flowers and wood,have been reported from the Cretaceous and Paleogene strata of the Northern Hemisphere.However,Neogene records of Mimosoideae are relatively scarce.In this study,fossil pods and leaves belonging to the genus Aibizzia from the Bangmai Formation of Yunnan,China were described.They were assigned to three species,including Albizzia scalpeUiformis Guo,Li and Xie Emended,Albizzia cf.kalkora(Roxb.)Prain and Albizzia sp.The occurrence of Albizzia fossils from Lincang not only gives important information on the Neogene plant diversity from Yunnan--a worldwide famous biological hotspot--but also provides additional evidence for its phytogeographic history.
基金Publication of this paper is supported by the National Natural Science Foundation of China （30424813） and Science Publication Foundation of the Chinese Academy of Sciences. Acknowledgements The authors thank Dr EW Noh, Biotechnology Division, Korea Forest Research Institute （KFRI）, Suwon, Korea, for his critical evaluation and valuable suggestions during the preparation of the manuscript.
文摘Changes in cellular isoflavone （daidzein and genistein） contents were monitored in root cultures of Albizzia kalkora （Roxb.） Prain after feeding different ratios of NH4^＋/NO3^- and treatment with a biotic elicitor （three strains of Rhizobium sp.）. The NH4^＋/NO3^- ratio appears to be positively correlated with daidzein content in the roots and shows a negative correlation with genistein. Among the three different strains of Rhizobium used, the strain ATCC 15834 caused a 35% increase in daidzein production by infection. In the case of genistein, maximum production （94%） was obtained when cultures were treated on Day 6 by the strains ATCC 15834 and KCTC 1541. The biosynthetic pathway of the two isoflavones apparently reacts differently to the same culture conditions and the same strains of Rhizobium. Therefore, the present data suggest that the production of daidzein and genistein could be modulated by changing the NH4^＋/NO3^- ratio and the application of Rhizobium.
