Purpose: This randomized controlled trial (RCT) protocol was designed to evaluate the effectiveness of the Cancer Pain Monitoring System (CAPAMOS), a telenursing system designed to alleviate pain in ambulatory patient...Purpose: This randomized controlled trial (RCT) protocol was designed to evaluate the effectiveness of the Cancer Pain Monitoring System (CAPAMOS), a telenursing system designed to alleviate pain in ambulatory patients with advanced cancer. Methods: The study design involved a randomized controlled trial consisting of an intervention group using CAPAMOS and a control group that received usual care. At the time of enrollment, both groups will be given a questionnaire regarding issues, such as concerns related to cancer pain and self-management of opioid medication. Patients will then receive pain relief education based on the results of the questionnaire. Subjects in the control group will receive a pain diary and pain-relief pamphlet that acts as an educational tool. They could also call the outpatient clinic if they wanted to ask for a nursing consultation. The intervention group will be able to use CAPAMOS to manage their pain and receive video consultation with a telenurse, who is an oncology nursing specialist. Educational tools will be built into CAPAMOS. The study will be conducted for one month. The primary endpoint of this study was to calculate the Japanese Brief Pain Inventory score. The secondary endpoints were to assess the opioid medication self-management, Barriers Questionnaire, Japanese EuroQol 5-dimensions 5-level, and economic evaluation. Assessment items will be evaluated at registration and 2 and 4 weeks after registration. Conclusions: A RCT based on this protocol is expected to validate the efficacy of telenursing using CAPAMOS in patients with advanced cancer and pain.展开更多
Objective: To observe the effect of Astragalus injection (AI) combined with chemotherapy on quality of life (QOF) in patients with advanced non-small cell lung caner (NSCLC). Methods: Sixty NSCLC patients were randoml...Objective: To observe the effect of Astragalus injection (AI) combined with chemotherapy on quality of life (QOF) in patients with advanced non-small cell lung caner (NSCLC). Methods: Sixty NSCLC patients were randomly divided into the treated group (n=30,treated with AI combined with chemotherapy) and the control group (n=30, treated with chemotherapy alone). Chemotherapy of MVP protocol was applied to both groups. AI was supplemented to the treated group by intravenous dripping 60 ml per day. Treatment of 21-28 days consisted one treatment cycle, and 2-3 cycles were applied. WResults: The effective rate in the treated group was 40.0% and in the control group was 36.7%, the mean remission rate in them being 5.4 month s and 3.3 months, the median survival period 11 month and 7 month and the 1-year survival rate 46.75% and 30.0%, respectively, the difference of these indexes between the two groups were all significant (P<0 05). Moreover, the clinical improving rate and QOF elevation rate in the treated group was 80.4% and 43.3%, as compared with those in the control group (50.0% and 23.3% respectively), the different was also significant (P<0 01). Conclusion: AI combined with chemotherapy can significantly improve the QOF in NSCLC patients of advanced stage.展开更多
The experiment will apply pain management to patients with advanced tumors, further improve the clinical effect of palliative care, and provide professional medical services for patients' pain relief. Methods: pat...The experiment will apply pain management to patients with advanced tumors, further improve the clinical effect of palliative care, and provide professional medical services for patients' pain relief. Methods: patients with advanced cancer admitted from February 2018 to February 2019 were selected as the research subjects, and a total of 80 patients met the inclusion criteria of the survey. They were divided into two groups by random drawing. The control group received conventional nursing measures (40 patients), and the observation group received pain management (41 patients), and the outcome of palliative care was analyzed. Results: in terms of nursing quality, the NRS pain score of observation group was (3.96 ± 1.24) points, and that of control group was (4.87 ± 1.63) points, the difference was statistically significant (P < 0.05). Meanwhile, in the survey of daily living ability, the scores of Barthel scale in the observation group and the control group were (80.55 ± 4.93) points and (69.35 ± 5.19) points, respectively. The difference was statistically significant. Finally, in the family satisfaction survey, the observation group was 95.0%, while the control group was 87.5%. The observation group more approved of the nursing plan. Conclusion: pain management is helpful to improve the pain of advanced tumor patients, improve the overall quality of palliative care, and further improve the quality of life. It has clinical promotion value.展开更多
Lung cancer is the leading cause of cancerrelated mortality in China.（1＇2） Meanwhile, the average life expectancy in the aging population has increased from 46 years in 1950 to 75 years in 2010.
Current Situation and Problems of the Treatment in Advanced Prostate Cancer In recent years,the incidence of prostate cancer shows a rising trend in China with an increase of 70%and has been the first place in the gro...Current Situation and Problems of the Treatment in Advanced Prostate Cancer In recent years,the incidence of prostate cancer shows a rising trend in China with an increase of 70%and has been the first place in the growth rate of malignant tumor in the male reproductive system. Prostate cancer has become a serious threat to male senior’s health.Because of the application of展开更多
Non-small cell lung cancer （NSCLC） is the leading cause of cancer death in the industrialized world. Despite significant progress in early stage of the disease, the overall survival rates for advanced disease remain...Non-small cell lung cancer （NSCLC） is the leading cause of cancer death in the industrialized world. Despite significant progress in early stage of the disease, the overall survival rates for advanced disease remain low. Herein we present a case of NSCLC who was treated with Chinese medicine and chemotherapy with a longer overall survival.展开更多
Aim:To evaluate the effectiveness of lymphovenular anastomosis(LVA)under local anesthesia for patients with high American Society of Anesthesiologists Physical Status(ASA PS)score.Methods:From January 2019 to January ...Aim:To evaluate the effectiveness of lymphovenular anastomosis(LVA)under local anesthesia for patients with high American Society of Anesthesiologists Physical Status(ASA PS)score.Methods:From January 2019 to January 2021,we collected a total of 29 patients with lymphedema stage III and IV,operated upon with LVA by a single surgeon in a medical center.These patients had poor responses to compression therapies.After surgery,the patients underwent complex decongestive therapy consisting of the continuous wearing of an elastic stocking.To examine the effect of LVA,all data were collected,and differences in preoperative and postoperative means were analyzed.Results:Twenty-nine patients with high ASA PS score(>3)were followed after lymphovenular anastomosis and postoperative compression therapies.Twenty-one of 29 patients were survivors of oncological diseases and continued oncological therapies.The average duration of edema of these patients before LVA was 25±5.0 years.The average number of anastomosis for each patient was 6.8±2.2;the methods of anesthesia had no significant influence on these numbers.The average follow-up period was 7.8±0.85 months,and the result was considered effective(26/29 patients;89.7%).The average reduction of the circumference in affected limbs was 4.40%±3.67%of the preoperative excess length.There were no perioperative complications in this study.Conclusion:Lymphovenular anastomosis can be performed under local anesthesia,especially in patients with high risks of general anesthesia(ASA PS score>3).By this way,we could achieve adequate anastomosis and effective treatment of lymphedema in advanced cancer patients as well.展开更多
文摘Purpose: This randomized controlled trial (RCT) protocol was designed to evaluate the effectiveness of the Cancer Pain Monitoring System (CAPAMOS), a telenursing system designed to alleviate pain in ambulatory patients with advanced cancer. Methods: The study design involved a randomized controlled trial consisting of an intervention group using CAPAMOS and a control group that received usual care. At the time of enrollment, both groups will be given a questionnaire regarding issues, such as concerns related to cancer pain and self-management of opioid medication. Patients will then receive pain relief education based on the results of the questionnaire. Subjects in the control group will receive a pain diary and pain-relief pamphlet that acts as an educational tool. They could also call the outpatient clinic if they wanted to ask for a nursing consultation. The intervention group will be able to use CAPAMOS to manage their pain and receive video consultation with a telenurse, who is an oncology nursing specialist. Educational tools will be built into CAPAMOS. The study will be conducted for one month. The primary endpoint of this study was to calculate the Japanese Brief Pain Inventory score. The secondary endpoints were to assess the opioid medication self-management, Barriers Questionnaire, Japanese EuroQol 5-dimensions 5-level, and economic evaluation. Assessment items will be evaluated at registration and 2 and 4 weeks after registration. Conclusions: A RCT based on this protocol is expected to validate the efficacy of telenursing using CAPAMOS in patients with advanced cancer and pain.
文摘Objective: To observe the effect of Astragalus injection (AI) combined with chemotherapy on quality of life (QOF) in patients with advanced non-small cell lung caner (NSCLC). Methods: Sixty NSCLC patients were randomly divided into the treated group (n=30,treated with AI combined with chemotherapy) and the control group (n=30, treated with chemotherapy alone). Chemotherapy of MVP protocol was applied to both groups. AI was supplemented to the treated group by intravenous dripping 60 ml per day. Treatment of 21-28 days consisted one treatment cycle, and 2-3 cycles were applied. WResults: The effective rate in the treated group was 40.0% and in the control group was 36.7%, the mean remission rate in them being 5.4 month s and 3.3 months, the median survival period 11 month and 7 month and the 1-year survival rate 46.75% and 30.0%, respectively, the difference of these indexes between the two groups were all significant (P<0 05). Moreover, the clinical improving rate and QOF elevation rate in the treated group was 80.4% and 43.3%, as compared with those in the control group (50.0% and 23.3% respectively), the different was also significant (P<0 01). Conclusion: AI combined with chemotherapy can significantly improve the QOF in NSCLC patients of advanced stage.
文摘The experiment will apply pain management to patients with advanced tumors, further improve the clinical effect of palliative care, and provide professional medical services for patients' pain relief. Methods: patients with advanced cancer admitted from February 2018 to February 2019 were selected as the research subjects, and a total of 80 patients met the inclusion criteria of the survey. They were divided into two groups by random drawing. The control group received conventional nursing measures (40 patients), and the observation group received pain management (41 patients), and the outcome of palliative care was analyzed. Results: in terms of nursing quality, the NRS pain score of observation group was (3.96 ± 1.24) points, and that of control group was (4.87 ± 1.63) points, the difference was statistically significant (P < 0.05). Meanwhile, in the survey of daily living ability, the scores of Barthel scale in the observation group and the control group were (80.55 ± 4.93) points and (69.35 ± 5.19) points, respectively. The difference was statistically significant. Finally, in the family satisfaction survey, the observation group was 95.0%, while the control group was 87.5%. The observation group more approved of the nursing plan. Conclusion: pain management is helpful to improve the pain of advanced tumor patients, improve the overall quality of palliative care, and further improve the quality of life. It has clinical promotion value.
基金Supported by the National Natural Science Foundation of China(No.81273718 and No.81102719)
文摘Lung cancer is the leading cause of cancerrelated mortality in China.（1＇2） Meanwhile, the average life expectancy in the aging population has increased from 46 years in 1950 to 75 years in 2010.
基金Supported by the National Natural Science Foundation of China(No.30873268)
文摘Current Situation and Problems of the Treatment in Advanced Prostate Cancer In recent years,the incidence of prostate cancer shows a rising trend in China with an increase of 70%and has been the first place in the growth rate of malignant tumor in the male reproductive system. Prostate cancer has become a serious threat to male senior’s health.Because of the application of
文摘Non-small cell lung cancer （NSCLC） is the leading cause of cancer death in the industrialized world. Despite significant progress in early stage of the disease, the overall survival rates for advanced disease remain low. Herein we present a case of NSCLC who was treated with Chinese medicine and chemotherapy with a longer overall survival.
文摘Aim:To evaluate the effectiveness of lymphovenular anastomosis(LVA)under local anesthesia for patients with high American Society of Anesthesiologists Physical Status(ASA PS)score.Methods:From January 2019 to January 2021,we collected a total of 29 patients with lymphedema stage III and IV,operated upon with LVA by a single surgeon in a medical center.These patients had poor responses to compression therapies.After surgery,the patients underwent complex decongestive therapy consisting of the continuous wearing of an elastic stocking.To examine the effect of LVA,all data were collected,and differences in preoperative and postoperative means were analyzed.Results:Twenty-nine patients with high ASA PS score(>3)were followed after lymphovenular anastomosis and postoperative compression therapies.Twenty-one of 29 patients were survivors of oncological diseases and continued oncological therapies.The average duration of edema of these patients before LVA was 25±5.0 years.The average number of anastomosis for each patient was 6.8±2.2;the methods of anesthesia had no significant influence on these numbers.The average follow-up period was 7.8±0.85 months,and the result was considered effective(26/29 patients;89.7%).The average reduction of the circumference in affected limbs was 4.40%±3.67%of the preoperative excess length.There were no perioperative complications in this study.Conclusion:Lymphovenular anastomosis can be performed under local anesthesia,especially in patients with high risks of general anesthesia(ASA PS score>3).By this way,we could achieve adequate anastomosis and effective treatment of lymphedema in advanced cancer patients as well.
