Rheumatoid arthritis(RA)patients face significant psychological challenges alongside physical symptoms,necessitating a comprehensive understanding of how psychological vulnerability and adaptation patterns evolve thro...Rheumatoid arthritis(RA)patients face significant psychological challenges alongside physical symptoms,necessitating a comprehensive understanding of how psychological vulnerability and adaptation patterns evolve throughout the disease course.This review examined 95 studies(2000-2025)from PubMed,Web of Science,and CNKI databases including longitudinal cohorts,randomized controlled trials,and mixed-methods research,to characterize the complex interplay between biological,psychological,and social factors affecting RA patients’mental health.Findings revealed three distinct vulnerability trajectories(45%persistently low,30%fluctuating improvement,25%persistently high)and four adaptation stages,with critical intervention periods occurring 3-6 months postdiagnosis and during disease flares.Multiple factors significantly influence psychological outcomes,including gender(females showing 1.8-fold increased risk),age(younger patients experiencing 42%higher vulnerability),pain intensity,inflammatory markers,and neuroendocrine dysregulation(48%showing cortisol rhythm disruption).Early psychological intervention(within 3 months of diagnosis)demonstrated robust benefits,reducing depression incidence by 42%with effects persisting 24-36 months,while different modalities showed complementary advantages:Cognitive behavioral therapy for depression(Cohen’s d=0.68),mindfulness for pain acceptance(38%improvement),and peer support for meaning reconstruction(25.6%increase).These findings underscore the importance of integrating routine psychological assessment into standard RA care,developing stage-appropriate interventions,and advancing research toward personalized biopsychosocial approaches that address the dynamic psychological dimensions of the disease.展开更多
After several years of intense study, the most urgent problem those college students must face is employment, what＇ s more, with the sustaining development of China＇ s economy and the accelerating pace of social pro...After several years of intense study, the most urgent problem those college students must face is employment, what＇ s more, with the sustaining development of China＇ s economy and the accelerating pace of social progress, the society shows much more need for the comprehensiveness and adaptation ability of talents. However, under the influence of long-term examination-oriented education, college students are only content with the courses required now which leads to the lack of large scope of expertise and ability to solve practical problems, being narrow-minded, and having poor flexibility, creativity and manipulative ability. With the addition of the significant differences between the campus and the society, many college graduates always have the feeling of maladjuslanent when entering the society, for example, they are usually lack of effective learning methods, strong social responsibilities and self-learning abilities and have poor understanding and mastery of professional knowledge, poor unity consciousness, poor manipulative ability in social practices and poor cognitive competence, furthermore ,they tend to have great intercommunicative obstacles and can not evaluate themselves and others correctly.展开更多
Many landslides in reservoir areas continuously deform under cyclic water level fluctuations due to reservoir operations. In this paper,a landslide model, developed for a typical colluvial landslide in the Three Gorge...Many landslides in reservoir areas continuously deform under cyclic water level fluctuations due to reservoir operations. In this paper,a landslide model, developed for a typical colluvial landslide in the Three Gorges Reservoir area, is used to study the effect of cyclic water level fluctuations on the landslide. Five cyclic water level fluctuations were implemented in the test, and the fluctuation rate in the last two fluctuations doubled over the first three fluctuations. The pore water pressure and lateral landslide profiles were obtained during the test. A measurement of the landslide soil loss was proposed to quantitatively evaluate the influence of water level fluctuations. The test results show that the first water level rising is most negative to the landslide among the five cycles. The fourth drawdown with a higher drawdown rate caused further large landslide deformation. An increase of the water level drawdown rate is much more unfavorable to the landslide than an increase of the water level rising rate. In addition, the landslide was found to have an adaptive ability to resist subsequent water level fluctuations after undergoing large deformation during a water level fluctuation. The landslide deformation and observations in the field were found to support the test results well.展开更多
基金Supported by Chongqing Health Commission and Chongqing Science and Technology Bureau,No.2023MSXM182。
文摘Rheumatoid arthritis(RA)patients face significant psychological challenges alongside physical symptoms,necessitating a comprehensive understanding of how psychological vulnerability and adaptation patterns evolve throughout the disease course.This review examined 95 studies(2000-2025)from PubMed,Web of Science,and CNKI databases including longitudinal cohorts,randomized controlled trials,and mixed-methods research,to characterize the complex interplay between biological,psychological,and social factors affecting RA patients’mental health.Findings revealed three distinct vulnerability trajectories(45%persistently low,30%fluctuating improvement,25%persistently high)and four adaptation stages,with critical intervention periods occurring 3-6 months postdiagnosis and during disease flares.Multiple factors significantly influence psychological outcomes,including gender(females showing 1.8-fold increased risk),age(younger patients experiencing 42%higher vulnerability),pain intensity,inflammatory markers,and neuroendocrine dysregulation(48%showing cortisol rhythm disruption).Early psychological intervention(within 3 months of diagnosis)demonstrated robust benefits,reducing depression incidence by 42%with effects persisting 24-36 months,while different modalities showed complementary advantages:Cognitive behavioral therapy for depression(Cohen’s d=0.68),mindfulness for pain acceptance(38%improvement),and peer support for meaning reconstruction(25.6%increase).These findings underscore the importance of integrating routine psychological assessment into standard RA care,developing stage-appropriate interventions,and advancing research toward personalized biopsychosocial approaches that address the dynamic psychological dimensions of the disease.
文摘After several years of intense study, the most urgent problem those college students must face is employment, what＇ s more, with the sustaining development of China＇ s economy and the accelerating pace of social progress, the society shows much more need for the comprehensiveness and adaptation ability of talents. However, under the influence of long-term examination-oriented education, college students are only content with the courses required now which leads to the lack of large scope of expertise and ability to solve practical problems, being narrow-minded, and having poor flexibility, creativity and manipulative ability. With the addition of the significant differences between the campus and the society, many college graduates always have the feeling of maladjuslanent when entering the society, for example, they are usually lack of effective learning methods, strong social responsibilities and self-learning abilities and have poor understanding and mastery of professional knowledge, poor unity consciousness, poor manipulative ability in social practices and poor cognitive competence, furthermore ,they tend to have great intercommunicative obstacles and can not evaluate themselves and others correctly.
基金funded by the Key Program of National Natural Science Foundation of China (41630643)the National Key Research and Development Program of China (2017YFC1501302)the Fundamental Research Funds for the Central Universities, China University of Geosciences (Wuhan) (CUGCJ1701)
文摘Many landslides in reservoir areas continuously deform under cyclic water level fluctuations due to reservoir operations. In this paper,a landslide model, developed for a typical colluvial landslide in the Three Gorges Reservoir area, is used to study the effect of cyclic water level fluctuations on the landslide. Five cyclic water level fluctuations were implemented in the test, and the fluctuation rate in the last two fluctuations doubled over the first three fluctuations. The pore water pressure and lateral landslide profiles were obtained during the test. A measurement of the landslide soil loss was proposed to quantitatively evaluate the influence of water level fluctuations. The test results show that the first water level rising is most negative to the landslide among the five cycles. The fourth drawdown with a higher drawdown rate caused further large landslide deformation. An increase of the water level drawdown rate is much more unfavorable to the landslide than an increase of the water level rising rate. In addition, the landslide was found to have an adaptive ability to resist subsequent water level fluctuations after undergoing large deformation during a water level fluctuation. The landslide deformation and observations in the field were found to support the test results well.
