For realizing the effective flotation of refractory copper ox-idized ores and developing the activation-flotation theory , the influences of nine different organic chelating agents on xanthate collection pcnver and it...For realizing the effective flotation of refractory copper ox-idized ores and developing the activation-flotation theory , the influences of nine different organic chelating agents on xanthate collection pcnver and its adsorption characteristics ivere studied in the flotation of malachite and chrysocolla representatively selected by means of XPS,IR, absorbed quanti-ty measurements and flotation tests.For easily-dissolved malachite flotation , a small amount of chelating agent can obviously enhance xanthate collecting power and make malachite floated easily , and so reduces the consumption of xanthate. For hard-dis-晄olved chrysocolla, chelating agent is able to increase its recovery to 90% , but the chelating agent consumption is high. Chelating agent and xanthate can produce synergistic adsorptions, which follmv Freundlich's adsorption equation on malachite and Chrysocolla surfaces. The high chemical activity of chelating agent and its synergistic activation on xanthate are the key to improving xanthate collection poiver. The synergistic activation of chelat-ing agent on xanthate on melachite surfaces is clearly stronger than on chrysocolla surfaces. According to experimental results, it can be thought that the synergistic activation results from the synergistic complexation of chelating agent and xanthate with copper ions to form biligand-tribasic co-ordination complex.展开更多
We studied the activation of β2-adrenergic receptor(β2AR) by norepinephrine, epinephrine and isoprote- renol using docking and molecular dynamics(MD) simulation. The simulation was done on the assumption that β...We studied the activation of β2-adrenergic receptor(β2AR) by norepinephrine, epinephrine and isoprote- renol using docking and molecular dynamics(MD) simulation. The simulation was done on the assumption that β2AR was surrounded with explicit water and infinite lipid bilayer membrane at body temperature. So the result should be close to that under the physiological conditions. We calculated the structure of binding sites in β2AR for the three ac- tivators. We also simulated the change of the conformation ofβ2AR in the transmembrane regions(TMs), in the mo- lecular switches, and in the conserved DRY(Aspartic acid, Arginine and Tyrosine) motif. This study provides detailed information concerning the structure ofβ2AR during activation process.展开更多
Protein energy malnutrition is the main cause of immunodeficiency and, secondarily, of several infections. However, immune cell activation is involved in several pathophysiological processes that play a crucial role i...Protein energy malnutrition is the main cause of immunodeficiency and, secondarily, of several infections. However, immune cell activation is involved in several pathophysiological processes that play a crucial role in the appearance of cardiovascular disease(CVD) or cancer. The aim of this review is to update the knowledge of the modulation of immune cell activation by different dietary patterns and its components focusing on CVD or cancer. While a westernized high-saturated fat highcarbohydrate diet is positively associated with lowgrade inflammation, vegetable- and fruit-based diets rich in monounsaturated fatty acids, polyunsaturated fatty acids and polyphenols, key nutrients of Mediterranean diet, decrease the levels of cellular and circulating inflammatory biomarkers thereby reducing the risk of related chronic diseases.展开更多
最近,佰钰推出了新系列的准系统产品——Activa,和我们之前测试的Access+系列一样.属于佰钰MMPC(Micro Media PC)家族,Access+在开机时通过威盛的ETBIOS技术.在不进入系统的情况下实现DVD/CD的播放功能。Activa系列则不同.设计...最近,佰钰推出了新系列的准系统产品——Activa,和我们之前测试的Access+系列一样.属于佰钰MMPC(Micro Media PC)家族,Access+在开机时通过威盛的ETBIOS技术.在不进入系统的情况下实现DVD/CD的播放功能。Activa系列则不同.设计上它采用了独立的供电模组和硬件解码模块。展开更多
The process of order to recover aluminum investigated. The CS was activating coal spoil (CS) in as a high value product was first characterized by X-ray fluorescence (XRF), X-ray diffraction (XRD) and thermo- gr...The process of order to recover aluminum investigated. The CS was activating coal spoil (CS) in as a high value product was first characterized by X-ray fluorescence (XRF), X-ray diffraction (XRD) and thermo- gravimetric analysis-differential scanning calorimetry (TGA-DSC) in order to determine the chemical and mineral compositions of the CS. Then a mechanothermal activation method was adopted to increase the aluminum activity in the coal spoil. Over 95% of the aluminum in the CS could be extracted using this activation method. The mechanothermal activation process promoted the destruc- tion of kaolinite structures and hindered the formation of amorphous γ-Al2O3. This resulted in a high aluminum leaching activity in the mechanothermally activated CS.展开更多
为提升矿工的风险感知水平,基于文献调研和试验研究,将噪声暴露分为0、15、30、45 min 4阶段,设计不同噪声暴露时间风险感知任务试验,采集被试的功能性近红外光谱(fNIRS)与行为数据,运用配对t检验、非参数检验、Pearson相关性分析方法,...为提升矿工的风险感知水平,基于文献调研和试验研究,将噪声暴露分为0、15、30、45 min 4阶段,设计不同噪声暴露时间风险感知任务试验,采集被试的功能性近红外光谱(fNIRS)与行为数据,运用配对t检验、非参数检验、Pearson相关性分析方法,探究不同噪声暴露时间对矿工风险感知水平的影响关系。结果表明:(1)被试的正确率受噪声暴露时间影响显著,随暴露时间的延长,正确率呈“先升后降”的趋势;(2)不同噪声暴露时间下进行风险感知任务显著激活位于眶额叶(OFC)、额极区(FPC)与背外侧前额叶(dlPFC)区域的通道,且左半脑激活程度略大于右半脑;(3)不同阶段脑区间呈现阶段性协作关系。无噪声阶段背外侧前额叶与额极区协作,噪声暴露时间为15 min时,额极区与眶额叶协作增强,暴露30与45 min,背外侧前额叶左右半球间协作增强。展开更多
文摘For realizing the effective flotation of refractory copper ox-idized ores and developing the activation-flotation theory , the influences of nine different organic chelating agents on xanthate collection pcnver and its adsorption characteristics ivere studied in the flotation of malachite and chrysocolla representatively selected by means of XPS,IR, absorbed quanti-ty measurements and flotation tests.For easily-dissolved malachite flotation , a small amount of chelating agent can obviously enhance xanthate collecting power and make malachite floated easily , and so reduces the consumption of xanthate. For hard-dis-晄olved chrysocolla, chelating agent is able to increase its recovery to 90% , but the chelating agent consumption is high. Chelating agent and xanthate can produce synergistic adsorptions, which follmv Freundlich's adsorption equation on malachite and Chrysocolla surfaces. The high chemical activity of chelating agent and its synergistic activation on xanthate are the key to improving xanthate collection poiver. The synergistic activation of chelat-ing agent on xanthate on melachite surfaces is clearly stronger than on chrysocolla surfaces. According to experimental results, it can be thought that the synergistic activation results from the synergistic complexation of chelating agent and xanthate with copper ions to form biligand-tribasic co-ordination complex.
基金Supported by the Young and Middle-Aged Scientists Research Awards Foundation of Shangdong Province,China(No.BS2011SW002)the Research Foundation for Advanced Talents of Ludong University,China(No.LY2011017)
文摘We studied the activation of β2-adrenergic receptor(β2AR) by norepinephrine, epinephrine and isoprote- renol using docking and molecular dynamics(MD) simulation. The simulation was done on the assumption that β2AR was surrounded with explicit water and infinite lipid bilayer membrane at body temperature. So the result should be close to that under the physiological conditions. We calculated the structure of binding sites in β2AR for the three ac- tivators. We also simulated the change of the conformation ofβ2AR in the transmembrane regions(TMs), in the mo- lecular switches, and in the conserved DRY(Aspartic acid, Arginine and Tyrosine) motif. This study provides detailed information concerning the structure ofβ2AR during activation process.
文摘Protein energy malnutrition is the main cause of immunodeficiency and, secondarily, of several infections. However, immune cell activation is involved in several pathophysiological processes that play a crucial role in the appearance of cardiovascular disease(CVD) or cancer. The aim of this review is to update the knowledge of the modulation of immune cell activation by different dietary patterns and its components focusing on CVD or cancer. While a westernized high-saturated fat highcarbohydrate diet is positively associated with lowgrade inflammation, vegetable- and fruit-based diets rich in monounsaturated fatty acids, polyunsaturated fatty acids and polyphenols, key nutrients of Mediterranean diet, decrease the levels of cellular and circulating inflammatory biomarkers thereby reducing the risk of related chronic diseases.
文摘最近,佰钰推出了新系列的准系统产品——Activa,和我们之前测试的Access+系列一样.属于佰钰MMPC(Micro Media PC)家族,Access+在开机时通过威盛的ETBIOS技术.在不进入系统的情况下实现DVD/CD的播放功能。Activa系列则不同.设计上它采用了独立的供电模组和硬件解码模块。
基金This work was financially supported by the National High Technology Research and Development Program of China (Grant No. 2011AA06A102), the National Natural Science Foundation ofChina (Grant No. 21306053), the Key Project of Scientific Research Innovation of Shanghai Municipal Education Commission (Grant No. 14ZZ063), and the Fundamental Research Fund for the Central Universities (WB1213008).
文摘The process of order to recover aluminum investigated. The CS was activating coal spoil (CS) in as a high value product was first characterized by X-ray fluorescence (XRF), X-ray diffraction (XRD) and thermo- gravimetric analysis-differential scanning calorimetry (TGA-DSC) in order to determine the chemical and mineral compositions of the CS. Then a mechanothermal activation method was adopted to increase the aluminum activity in the coal spoil. Over 95% of the aluminum in the CS could be extracted using this activation method. The mechanothermal activation process promoted the destruc- tion of kaolinite structures and hindered the formation of amorphous γ-Al2O3. This resulted in a high aluminum leaching activity in the mechanothermally activated CS.
文摘为提升矿工的风险感知水平,基于文献调研和试验研究,将噪声暴露分为0、15、30、45 min 4阶段,设计不同噪声暴露时间风险感知任务试验,采集被试的功能性近红外光谱(fNIRS)与行为数据,运用配对t检验、非参数检验、Pearson相关性分析方法,探究不同噪声暴露时间对矿工风险感知水平的影响关系。结果表明:(1)被试的正确率受噪声暴露时间影响显著,随暴露时间的延长,正确率呈“先升后降”的趋势;(2)不同噪声暴露时间下进行风险感知任务显著激活位于眶额叶(OFC)、额极区(FPC)与背外侧前额叶(dlPFC)区域的通道,且左半脑激活程度略大于右半脑;(3)不同阶段脑区间呈现阶段性协作关系。无噪声阶段背外侧前额叶与额极区协作,噪声暴露时间为15 min时,额极区与眶额叶协作增强,暴露30与45 min,背外侧前额叶左右半球间协作增强。
基金the major scientific instruments and equipment development project of the Ministry of Science and Technology,China(2012YQ18011805)the science and technology project from the technology bureau of Chengdu(2014HM0100099SF)the project of science and technology innovation team of Sichuan province(2015TD0020)