TiO2 nanotube precursor was synthesized by the hydrothermal reaction of TiO2 powders with NaOH solution and the properties of the nanotube materials were tuned using different post-treatments. Transmission electron mi...TiO2 nanotube precursor was synthesized by the hydrothermal reaction of TiO2 powders with NaOH solution and the properties of the nanotube materials were tuned using different post-treatments. Transmission electron microscopic （TEM） observation revealed that the nanotube could be obtained by either a direct rinse with acid solution or rinse with distilled water followed by acid solution. The results of X-ray diffraction （XRD） and inductively coupled plasma （ICP） analysis indicated that the nanotube material was composed of H2Ti2O5·H2O. In addition, the photocatalytic activities of the resulting catalysts were found to be strongly dependent on the post-treatment. The results of the photocatalytic reaction showed that the degradation of Acid-red 3B dye fitted pseudo-zero-order kinetics and TiO2 nanotube prepared under direct rinse with acid solution exhibited a higher catalytic efficiency compared to other catalysts.展开更多
在许多类型的手术中应用氨甲环酸(tranexamic acid,TXA)可减少出血量和输血次数,但其对因癌症相关指征接受肝切除术患者的影响仍不清楚。为评估TXA对肝切除术患者出血、输血和围手术期并发症的影响,开展了此项多中心、随机、安慰剂对照...在许多类型的手术中应用氨甲环酸(tranexamic acid,TXA)可减少出血量和输血次数,但其对因癌症相关指征接受肝切除术患者的影响仍不清楚。为评估TXA对肝切除术患者出血、输血和围手术期并发症的影响,开展了此项多中心、随机、安慰剂对照临床研究。2014年12月1日至2022年11月8日,加拿大及美国共11家中心的1 384例患者符合入组标准,并随机分配至TXA组或安慰剂组。主要研究终点为手术开始至术后第7d红细胞输注。最终分析1 245例患者,TXA组16.32%患者(n=101)接受了红细胞输注,安慰剂组14.54%患者(n=91)接受了红细胞输注(OR=1.15,95%CI:0.84~1.56,P=0.38)。术中失血量(817.30 mL vs 836.70 mL,P=0.75)和术后0~7 d内总失血量(1504.00 mL vs 1551.20 mL,P=0.38)在两组之间无统计学差异。与安慰剂组相比,接受TXA治疗的患者并发症明显增多(OR=1.28,95%CI:1.02~1.60,P=0.03),静脉血栓栓塞无显著性差异(OR=1.68,95%CI:0.95~3.07,P=0.08)。在因癌症相关指征而行肝切除术的患者中,TXA并没有减少出血或输血,反而增加了围手术期并发症。因此,在尚未明确证明TXA有效的外科手术中采用TXA应持谨慎态度。展开更多
文摘TiO2 nanotube precursor was synthesized by the hydrothermal reaction of TiO2 powders with NaOH solution and the properties of the nanotube materials were tuned using different post-treatments. Transmission electron microscopic （TEM） observation revealed that the nanotube could be obtained by either a direct rinse with acid solution or rinse with distilled water followed by acid solution. The results of X-ray diffraction （XRD） and inductively coupled plasma （ICP） analysis indicated that the nanotube material was composed of H2Ti2O5·H2O. In addition, the photocatalytic activities of the resulting catalysts were found to be strongly dependent on the post-treatment. The results of the photocatalytic reaction showed that the degradation of Acid-red 3B dye fitted pseudo-zero-order kinetics and TiO2 nanotube prepared under direct rinse with acid solution exhibited a higher catalytic efficiency compared to other catalysts.
文摘在许多类型的手术中应用氨甲环酸(tranexamic acid,TXA)可减少出血量和输血次数,但其对因癌症相关指征接受肝切除术患者的影响仍不清楚。为评估TXA对肝切除术患者出血、输血和围手术期并发症的影响,开展了此项多中心、随机、安慰剂对照临床研究。2014年12月1日至2022年11月8日,加拿大及美国共11家中心的1 384例患者符合入组标准,并随机分配至TXA组或安慰剂组。主要研究终点为手术开始至术后第7d红细胞输注。最终分析1 245例患者,TXA组16.32%患者(n=101)接受了红细胞输注,安慰剂组14.54%患者(n=91)接受了红细胞输注(OR=1.15,95%CI:0.84~1.56,P=0.38)。术中失血量(817.30 mL vs 836.70 mL,P=0.75)和术后0~7 d内总失血量(1504.00 mL vs 1551.20 mL,P=0.38)在两组之间无统计学差异。与安慰剂组相比,接受TXA治疗的患者并发症明显增多(OR=1.28,95%CI:1.02~1.60,P=0.03),静脉血栓栓塞无显著性差异(OR=1.68,95%CI:0.95~3.07,P=0.08)。在因癌症相关指征而行肝切除术的患者中,TXA并没有减少出血或输血,反而增加了围手术期并发症。因此,在尚未明确证明TXA有效的外科手术中采用TXA应持谨慎态度。
