Abnormal uterine bleeding（AUB）, especially in the menopausal transition period,is showing a tendency of rising in recent years, and after treatment, high recurrence rate for the treatment of hormone treatment, the e...Abnormal uterine bleeding（AUB）, especially in the menopausal transition period,is showing a tendency of rising in recent years, and after treatment, high recurrence rate for the treatment of hormone treatment, the endometrial resection and uterine resection. But for patients with severe systemic disease with AUB, it may get worse with the conventional treatment. Novasure provides us with an effective measure for the treatment of AUB with active systemic lupus erythematosus（SLE）.展开更多
In order to fully understand the research progress of Chinese and Western medicine in the treatment of perimenopausal abnormal uterine bleeding,this paper reviews all kinds of research by referring to related literatu...In order to fully understand the research progress of Chinese and Western medicine in the treatment of perimenopausal abnormal uterine bleeding,this paper reviews all kinds of research by referring to related literature reports at home and abroad.The results showed that western medicine mainly used hormone drugs,supplemented by surgery,but the clinical adverse reactions were more and the recurrence rate was higher;traditional Chinese medicine often obtained satisfactory results through the treatment of traditional Chinese medicine,syndrome differentiation,stage treatment,acupuncture and other treatment methods,with fewer adverse reactions and low recurrence rate,but the effect of sudden collapse and hemostasis was slower;the combination of Chinese and Western medicine can learn from each other and become The research focus in recent years is worthy of further discussion.展开更多
ve To investigate the relationship between estradiol, progesterone and endothe-lin (ET) and abnormal uterine bleeding after using sub-dermal contraceptive implant
Objective:To explore the mechanism of the treatment of abnormal uterine bleeding with Radix Paeoniae Rubra-Cortex Moutan.Methods:To search the effective elements and action targets of paeony peony skin drug pair by se...Objective:To explore the mechanism of the treatment of abnormal uterine bleeding with Radix Paeoniae Rubra-Cortex Moutan.Methods:To search the effective elements and action targets of paeony peony skin drug pair by searching the pharmacology platform of traditional Chinese medicine system;to select the disease targets of abnormal uterine bleeding by searching the human gene information database;to select the common targets of drugs and diseases by R language,to construct the interaction network of drugs compounds action targets diseases by using the software of Cytoscape;to construct the protein-protein interaction network by using the string platform The interaction network(PPI)was used to visualize the results,and the bio information package of Bioconductor was used to analyze go function enrichment and KEGG pathway.Results:This study included 16 compounds and 67 key targets.After enrichment analysis,87 go functional items and 116 KEGG signaling pathways were obtained.Quercetin,scutellarin,kaempferol and stigmasterol in Radix Paeoniae Rubra-Cortex Moutan directly act on interleukin-6,epidermal growth factor receptor,cystatin 3,mitogen activated protein kinase 8,vascular endothelial growth factor and other related targets,and are mainly enriched in Kaposi sarcoma associated herpesvirus infection and hepatis B.Age-range,TNF and other signal pathways.Conclusion:Radix Paeoniae Rubra-Cortex Moutan may play the role of anti-cell proliferation and apoptosis,protection of vascular endothelium,anti-inflammatory response,regulation of hormone secretion,and improvement of antioxidant activity through multi-component and multi-target,and play the role of treatment of abnormal uterine bleeding.展开更多
Background: Retention of fetal bones is a rare cause of abnormal uterine bleeding. Others may present as subfertility, chronic pelvic pain, abnormal vaginal discharge, menometrorrhagia, dysmenorrhea and spontaneous ex...Background: Retention of fetal bones is a rare cause of abnormal uterine bleeding. Others may present as subfertility, chronic pelvic pain, abnormal vaginal discharge, menometrorrhagia, dysmenorrhea and spontaneous expulsion of bony fragments. Incidence is 0.26% among patients undergoing hysteroscopy. Aim: To document a pattern of presentation of retained fetal bone and its management. Case Presentation: Our patient is an 18-year old who presented with vaginal bleeding of four weeks duration and managed for abnormal uterine bleeding due to retained fetal bone following second trimester abortion. Conclusion: The use of transvaginal ultrasound in making diagnosis of retained fetal bone is effective. Treatment by removal of bones through evacuation by dilatation and curettage or hysteroscopy brings about resolution of symptoms. Use of pelvic ultrasonography to confirm complete evacuation of the uterus after abortion especially second trimester abortion could aid in early diagnosis and management of incomplete abortion.展开更多
Objective: to explore the value of Baogong Zhixue Granule combined with hysteroscopic electrotomy in the treatment of perimenopausal abnormal uterine bleeding. Methods: 323 patients with perimenopausal abnormal uterin...Objective: to explore the value of Baogong Zhixue Granule combined with hysteroscopic electrotomy in the treatment of perimenopausal abnormal uterine bleeding. Methods: 323 patients with perimenopausal abnormal uterine bleeding admitted by the department of gynecology in our hospital were selected for the study, which lasted from 2008 to 2021. The patients were divided into control group (n161) and observation group (n162). The control group was treated with routine hysteroscopic electrotomy, while the observation group was treated with Baogong Zhixue Granule. The clinical efficacy, postoperative complication rate, anemia status, sex hormone level and menstrual blood loss graph score were compared between the two groups. Results: the clinical effective rate of the observation group was 98.77%, higher than that of the control group (P0.05). The postoperative complication rate in the observation group was 1.85%, lower than that in the control group (P0.05). The anemia rate and repeated bleeding rate in the observation group were 12.35% and 0.62%, respectively, lower than those in the control group (P0.05). The bleeding stop time in the observation group was (4.52 ± 1.54) days, which was shorter than that in the control group (P0.05). After treatment, the menstrual blood loss graph score, LH level, FSH level and E2 level in the observation group were (3.04 ± 0.65) points, (8.89 ± 2.13) IU/L, (7.26 ± 2.55) IU/L and (208.65 ± 26.13) poml/L, respectively, compared with the control group (P0.05). Conclusion: Baogong Zhixue Granule combined with hysteroscopic electrotomy is effective in the treatment of perimenopausal abnormal uterine bleeding, which can improve the sex hormone level of patients, reduce postoperative complications, prevent anemia, and promote rehabilitation. It is worth popularizing.展开更多
Objective: to study the application of endocrine examination in abnormal uterine bleeding. Methods: 80 patients who participated in this study were all patients who received abnormal uterine bleeding in our hospital f...Objective: to study the application of endocrine examination in abnormal uterine bleeding. Methods: 80 patients who participated in this study were all patients who received abnormal uterine bleeding in our hospital from February 2018 to February 2019. All patients participating in the study underwent vaginal ultrasound examination first, followed by endocrine examination and then pathological examination, to compare the accuracy of the results of two different examinations. Results: the examination results of the above two examination methods were error with the pathological examination results. However, the positive rate of endocrine examination (90.00%) was significantly higher than that of vaginal ultrasound examination (70.00%) (P < 0.05). Conclusion: endocrine examination has a significantly high accuracy in the detection of abnormal uterine bleeding, which can further understand the disease development of patients and provide a reliable basis for the clinical diagnosis and treatment of patients and medical staff. It can be used as the main means to detect abnormal uterine bleeding, and is worthy of further application and promotion.展开更多
In recent years,the frequency of clinical occurrence of abnormal uterine bleeding in adolescence has gradually increased.In order to fully understand the research progress in the treatment of abnormal uterine bleeding...In recent years,the frequency of clinical occurrence of abnormal uterine bleeding in adolescence has gradually increased.In order to fully understand the research progress in the treatment of abnormal uterine bleeding in adolescence,various studies and clinical experience have been reviewed by consulting related literature reports.The results found that currently Western medicine mainly uses hormone drugs in clinical treatment,but there are risks such as more clinical adverse reactions and higher recurrence rate;traditional Chinese medicine(TCM)treatment has achieved satisfactory results,but the advantages of sudden collapse and hemostasis are not obvious.Combined TCM and Western medicine treatment,it can learn from each other and has become a research hotspot in recent years,which is worthy of an in-depth discussion.展开更多
INTRODUCTION Abnormal uterine bleeding(AUB)is the most common reason adolescent females visit gynaecologists.From the onset of menarche,symptoms such as heavy menstrual bleeding(HMB)and/or prolonged menstruation can a...INTRODUCTION Abnormal uterine bleeding(AUB)is the most common reason adolescent females visit gynaecologists.From the onset of menarche,symptoms such as heavy menstrual bleeding(HMB)and/or prolonged menstruation can affct both physical and mental health,with potential lifelong impacts.Despite its preva-lence,there are relatively few studies on AUB in adolescence,and China lacks relevant guidelines and consensus on the issue.展开更多
Uterine artery pseudoaneurysm(UAP)is a rare but potentially life-threatening complication that can occur following hysteroscopic surgery for endometrial polyp resection.This article discusses the case study by Kakinum...Uterine artery pseudoaneurysm(UAP)is a rare but potentially life-threatening complication that can occur following hysteroscopic surgery for endometrial polyp resection.This article discusses the case study by Kakinuma et al,which highlights the successful diagnosis and treatment of UAP in a 48-year-old primiparous woman.Utilizing advanced imaging techniques such as ultrasound and computed tomography(CT),the medical team was able to promptly identify the UAP and subsequently perform a uterine artery embolization to treat the condition.The study underscores the critical need for rapid diagnosis and intervention to prevent severe outcomes and provides practical clinical recommendations for managing similar cases.This article aims to expand on the study’s findings,discuss the clinical implications,and suggest future research directions to optimize the management of UAP post-hysteroscopic surgery.展开更多
Introduction: Uterine leiomyomas, or fibroids, are prevalent benign tumors affecting up to 70% of reproductive-age women in the United States, significantly impacting productivity and quality of life. Despite their co...Introduction: Uterine leiomyomas, or fibroids, are prevalent benign tumors affecting up to 70% of reproductive-age women in the United States, significantly impacting productivity and quality of life. Despite their commonality, the epidemiology and clinical patterns of leiomyomas in Puerto Rico remain inadequately researched. Methods: This study conducted a secondary data analysis using clinical, menstrual cycle characteristics, and demographic data from self-administered questionnaires of women undergoing diagnostic laparoscopy for endometriosis in Puerto Rico. Chi-square tests and t-tests analyzed categorical and continuous variables, respectively (p Results: Among 1,610 endometriosis cases, 312 included uterine fibroids. Prevalence estimates were 10.3% (40 years). Primiparous women averaged 22.14 years, with 40.71% having 2 - 3 pregnancies and 26.28% experiencing miscarriages. Symptoms included infertility (29.5%), dyspareunia (40.7%), severe pain (50%), and dysmenorrhea (75.6%). Comorbidities included ovarian cysts (52.2%) and abnormal uterine bleeding (37.8%). Conclusions: Advanced age, parity, and comorbidities like diabetes and hypertension were prevalent in our cohort. Understanding the epidemiological profile of women living in Puerto Rico with uterine fibroids is crucial for improving diagnostic awareness and enhancing patient care.展开更多
BACKGROUND Moyamoya disease is essentially an ischemic cerebrovascular disease.Here,we describe a case of acute recurrent cerebral infarction caused by moyamoya disease with concurrent adenomyosis which,to our knowled...BACKGROUND Moyamoya disease is essentially an ischemic cerebrovascular disease.Here,we describe a case of acute recurrent cerebral infarction caused by moyamoya disease with concurrent adenomyosis which,to our knowledge,is the first in the literature.A literature review is also presented.CASE SUMMARY A 38-year-old female presented to the Research and Treatment Center of Moyamoya Disease in our hospital with"left limb weakness"as the main symptom.She was diagnosed with acute cerebral infarction and moyamoya disease through magnetic resonance imaging and digital subtraction angiography.Prior to this,she had experienced a prolonged menstrual period of one-month duration.This was investigated and adenomyosis was diagnosed.After passing the acute cerebral infarction phase,the patient underwent surgery for adenomyosis followed by combined cerebral revascularization.During the postoperative follow-up,improvements of the perfusion imaging stage and modified Rankin Scale were observed.A review of the literature showed only 16 reported cases of gynecological diseases complicated with stroke.The clinical characteristics,pathogenesis,therapeutic effects,and long-term prognosis of these cases have been studied and discussed.CONCLUSION In patients with moyamoya disease,early management of gynecological-related bleeding disorders is essential to prevent the complications of cerebral events.展开更多
Objective:To explore the application of health education in the nursing care of patients with metrorrhagia and metrostaxis after hysteroscopic electrotomy and the effect on the occurrence of disease complications.Meth...Objective:To explore the application of health education in the nursing care of patients with metrorrhagia and metrostaxis after hysteroscopic electrotomy and the effect on the occurrence of disease complications.Methods:Totally 70 patients admitted from March 2018 to March 2019 were randomly divided into two groups.The control group was given routine nursing,while the observation group was given comprehensive health education combined with routine nursing.The unhealthy emotions(anxiety and depression)of patients were assessed using Hamilton Depression Scale(HAMD)and Hamilton Anxiety Scale(HAMA).The incidence of complications,and surgical related matters were recorded and compared between two groups after nursing interventions.Results:A lower HAMD score,A lower HAMA score,a shorter hospitalization time,a shorter operation time and a less intraoperative bleeding volume,a lower incidence rate of complications(massive bleeding and uterine perforation),and a higher degree of patients’cooperation in surgery were shown in observation group compared with control group after nursing intervention(P all<0.05).Conclusion:The application of health education in the nursing of metrorrhagia and metrostaxis patients can relieve the patients’anxiety and depression,improve their understanding and mastery of relevant disease knowledge and their ability to cope with bleeding and their self-health care,as well as reduce the incidence of complications and the length of hospital stay and promote the rehabilitation of patients.Therefore,it is worthy of clinical application.展开更多
BACKGROUND Atypical endometrial hyperplasia(AEH)is a common precancerous lesion of endometrial carcinoma(EC).The risk factors for AEH and EC directly or indirectly related to estrogen exposure include early menarche,n...BACKGROUND Atypical endometrial hyperplasia(AEH)is a common precancerous lesion of endometrial carcinoma(EC).The risk factors for AEH and EC directly or indirectly related to estrogen exposure include early menarche,nulliparity,polycystic ovarian syndrome,diabetes,and obesity.Both AEH and EC rarely occur in young patients(<40-years-old),who may desire to maintain their fertility.Evaluating the cancer risk of AEH patients is helpful for the determination of therapeutic plans.CASE SUMMARY We report a rare case of AEH in a 35-year-old woman who presented to the Hunan Provincial Maternal and Child Health Care Hospital with a large mass in the uterus.She married at 20-years-old,and had been married for more than 15 years to date.Several characteristics of this patient were observed,including nulliparity,limited sexual activity(intercourse 1-2 times a year)in recent years,and irregular vaginal bleeding for 2 years.Gynecological examination revealed an enlarged uterus,similar to the uterus size in the fourth month of pregnancy,and the uterine wall was relatively hard.Curettage was performed based on transvaginal sonography and magnetic resonance imaging results.Findings from the pathological examination were typical for AEH.The patient was cured after treatment with the standard therapy of high-dose progesterone.CONCLUSION In patients with intrauterine lumps that may be malignant,a pathological report should be obtained.展开更多
Covid-19 was declared a global pandemic by the World Health Organization;it has caused more than 4</span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;&...Covid-19 was declared a global pandemic by the World Health Organization;it has caused more than 4</span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">,</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">697</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">,</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">099 deaths worldwide. Since the discovery of Vaccines, the rate of infections and deaths </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">are</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> declining in countries that were able to conduct mass vaccination, making the vaccines the most effect tool in the fight against Covid-19. However</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">,</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> there is still vaccination skepticism. The side effects </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">of </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">vaccines could fuel more skepticism.</span></span></span><span><span><span style="font-family:""> </span></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;">There are emerging possible new side effects such as abnormal uterine bleeding post Covid-19 vaccination, for which health care providers and the population should be aware. In this paper, we are reporting three (3) cases of abnormal uterine bleeding which seems to be linked to Covid-19 vaccines. We reported </span><span style="font-family:Verdana;">two incidents of heavy menstrual bleeding and one incident of inter-menstrual </span><span style="font-family:Verdana;">bleeding which are likely associated with COVID 19 vaccination, even though the causality c</span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">ould </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">not be confirmed. Also both type</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">s</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> of vaccines, Messenger RNA and Adenovirus vector could possibly be associated with abnormal uterine bleeding. As research is still ongoing, more knowledge would be available, meanwhile, healthcare providers and the population should be made aware of the new possible side effects of Covid-19 vaccines.展开更多
For the treatment of premenstrual disease, it is particularly important to treat the spleen and kidney, because there are yin and yang in each viscera. Once the spleen yang is damaged, it can lead to premenstrual, whi...For the treatment of premenstrual disease, it is particularly important to treat the spleen and kidney, because there are yin and yang in each viscera. Once the spleen yang is damaged, it can lead to premenstrual, while the kidney yang damage can also lead to the spleen yang damage, yang damage and yin damage, which will also lead to early menstrual cycle. However, if the time delay is longer, it will develop into metrorrhagia and metrostaxis. It is necessary to take corresponding measures and timely treatment.展开更多
文摘Abnormal uterine bleeding（AUB）, especially in the menopausal transition period,is showing a tendency of rising in recent years, and after treatment, high recurrence rate for the treatment of hormone treatment, the endometrial resection and uterine resection. But for patients with severe systemic disease with AUB, it may get worse with the conventional treatment. Novasure provides us with an effective measure for the treatment of AUB with active systemic lupus erythematosus（SLE）.
基金Key research and development plan of Shandong Province(No.2019GSF108208).
文摘In order to fully understand the research progress of Chinese and Western medicine in the treatment of perimenopausal abnormal uterine bleeding,this paper reviews all kinds of research by referring to related literature reports at home and abroad.The results showed that western medicine mainly used hormone drugs,supplemented by surgery,but the clinical adverse reactions were more and the recurrence rate was higher;traditional Chinese medicine often obtained satisfactory results through the treatment of traditional Chinese medicine,syndrome differentiation,stage treatment,acupuncture and other treatment methods,with fewer adverse reactions and low recurrence rate,but the effect of sudden collapse and hemostasis was slower;the combination of Chinese and Western medicine can learn from each other and become The research focus in recent years is worthy of further discussion.
文摘ve To investigate the relationship between estradiol, progesterone and endothe-lin (ET) and abnormal uterine bleeding after using sub-dermal contraceptive implant
基金Fundamental Scientific Research Business Expenses of the Institute of Basic Theories of Traditional Chinese Medicine,China Academy of Chinese Medical Sciences(No.YZ-202006,YZ-1859)。
文摘Objective:To explore the mechanism of the treatment of abnormal uterine bleeding with Radix Paeoniae Rubra-Cortex Moutan.Methods:To search the effective elements and action targets of paeony peony skin drug pair by searching the pharmacology platform of traditional Chinese medicine system;to select the disease targets of abnormal uterine bleeding by searching the human gene information database;to select the common targets of drugs and diseases by R language,to construct the interaction network of drugs compounds action targets diseases by using the software of Cytoscape;to construct the protein-protein interaction network by using the string platform The interaction network(PPI)was used to visualize the results,and the bio information package of Bioconductor was used to analyze go function enrichment and KEGG pathway.Results:This study included 16 compounds and 67 key targets.After enrichment analysis,87 go functional items and 116 KEGG signaling pathways were obtained.Quercetin,scutellarin,kaempferol and stigmasterol in Radix Paeoniae Rubra-Cortex Moutan directly act on interleukin-6,epidermal growth factor receptor,cystatin 3,mitogen activated protein kinase 8,vascular endothelial growth factor and other related targets,and are mainly enriched in Kaposi sarcoma associated herpesvirus infection and hepatis B.Age-range,TNF and other signal pathways.Conclusion:Radix Paeoniae Rubra-Cortex Moutan may play the role of anti-cell proliferation and apoptosis,protection of vascular endothelium,anti-inflammatory response,regulation of hormone secretion,and improvement of antioxidant activity through multi-component and multi-target,and play the role of treatment of abnormal uterine bleeding.
文摘Background: Retention of fetal bones is a rare cause of abnormal uterine bleeding. Others may present as subfertility, chronic pelvic pain, abnormal vaginal discharge, menometrorrhagia, dysmenorrhea and spontaneous expulsion of bony fragments. Incidence is 0.26% among patients undergoing hysteroscopy. Aim: To document a pattern of presentation of retained fetal bone and its management. Case Presentation: Our patient is an 18-year old who presented with vaginal bleeding of four weeks duration and managed for abnormal uterine bleeding due to retained fetal bone following second trimester abortion. Conclusion: The use of transvaginal ultrasound in making diagnosis of retained fetal bone is effective. Treatment by removal of bones through evacuation by dilatation and curettage or hysteroscopy brings about resolution of symptoms. Use of pelvic ultrasonography to confirm complete evacuation of the uterus after abortion especially second trimester abortion could aid in early diagnosis and management of incomplete abortion.
文摘Objective: to explore the value of Baogong Zhixue Granule combined with hysteroscopic electrotomy in the treatment of perimenopausal abnormal uterine bleeding. Methods: 323 patients with perimenopausal abnormal uterine bleeding admitted by the department of gynecology in our hospital were selected for the study, which lasted from 2008 to 2021. The patients were divided into control group (n161) and observation group (n162). The control group was treated with routine hysteroscopic electrotomy, while the observation group was treated with Baogong Zhixue Granule. The clinical efficacy, postoperative complication rate, anemia status, sex hormone level and menstrual blood loss graph score were compared between the two groups. Results: the clinical effective rate of the observation group was 98.77%, higher than that of the control group (P0.05). The postoperative complication rate in the observation group was 1.85%, lower than that in the control group (P0.05). The anemia rate and repeated bleeding rate in the observation group were 12.35% and 0.62%, respectively, lower than those in the control group (P0.05). The bleeding stop time in the observation group was (4.52 ± 1.54) days, which was shorter than that in the control group (P0.05). After treatment, the menstrual blood loss graph score, LH level, FSH level and E2 level in the observation group were (3.04 ± 0.65) points, (8.89 ± 2.13) IU/L, (7.26 ± 2.55) IU/L and (208.65 ± 26.13) poml/L, respectively, compared with the control group (P0.05). Conclusion: Baogong Zhixue Granule combined with hysteroscopic electrotomy is effective in the treatment of perimenopausal abnormal uterine bleeding, which can improve the sex hormone level of patients, reduce postoperative complications, prevent anemia, and promote rehabilitation. It is worth popularizing.
文摘Objective: to study the application of endocrine examination in abnormal uterine bleeding. Methods: 80 patients who participated in this study were all patients who received abnormal uterine bleeding in our hospital from February 2018 to February 2019. All patients participating in the study underwent vaginal ultrasound examination first, followed by endocrine examination and then pathological examination, to compare the accuracy of the results of two different examinations. Results: the examination results of the above two examination methods were error with the pathological examination results. However, the positive rate of endocrine examination (90.00%) was significantly higher than that of vaginal ultrasound examination (70.00%) (P < 0.05). Conclusion: endocrine examination has a significantly high accuracy in the detection of abnormal uterine bleeding, which can further understand the disease development of patients and provide a reliable basis for the clinical diagnosis and treatment of patients and medical staff. It can be used as the main means to detect abnormal uterine bleeding, and is worthy of further application and promotion.
基金Scientific Research Project of Shaanxi Provincial Administration of Traditional Chinese Medicine(15-LC007)Project title:Observation on the clinical efficacy of Shaanxi Province famous traditional Chinese medicine professor He Fengjie on the treatment of late menstruation with the method of nourishing the kidney and regulating the week.Subject Innovation Team Project of Shaanxi University of Traditional Chinese Medicine(2019-YL08)。
文摘In recent years,the frequency of clinical occurrence of abnormal uterine bleeding in adolescence has gradually increased.In order to fully understand the research progress in the treatment of abnormal uterine bleeding in adolescence,various studies and clinical experience have been reviewed by consulting related literature reports.The results found that currently Western medicine mainly uses hormone drugs in clinical treatment,but there are risks such as more clinical adverse reactions and higher recurrence rate;traditional Chinese medicine(TCM)treatment has achieved satisfactory results,but the advantages of sudden collapse and hemostasis are not obvious.Combined TCM and Western medicine treatment,it can learn from each other and has become a research hotspot in recent years,which is worthy of an in-depth discussion.
文摘INTRODUCTION Abnormal uterine bleeding(AUB)is the most common reason adolescent females visit gynaecologists.From the onset of menarche,symptoms such as heavy menstrual bleeding(HMB)and/or prolonged menstruation can affct both physical and mental health,with potential lifelong impacts.Despite its preva-lence,there are relatively few studies on AUB in adolescence,and China lacks relevant guidelines and consensus on the issue.
基金Supported by Basic Science Research Program Through the National Research Foundation of Korea(NRF)Funded by the Ministry of Education,No.NRF-RS-2023-00237287 and No.NRF-2021S1A5A8062526Local Government-University Cooperation-Based Regional Innovation Projects,No.2021RIS-003.
文摘Uterine artery pseudoaneurysm(UAP)is a rare but potentially life-threatening complication that can occur following hysteroscopic surgery for endometrial polyp resection.This article discusses the case study by Kakinuma et al,which highlights the successful diagnosis and treatment of UAP in a 48-year-old primiparous woman.Utilizing advanced imaging techniques such as ultrasound and computed tomography(CT),the medical team was able to promptly identify the UAP and subsequently perform a uterine artery embolization to treat the condition.The study underscores the critical need for rapid diagnosis and intervention to prevent severe outcomes and provides practical clinical recommendations for managing similar cases.This article aims to expand on the study’s findings,discuss the clinical implications,and suggest future research directions to optimize the management of UAP post-hysteroscopic surgery.
文摘Introduction: Uterine leiomyomas, or fibroids, are prevalent benign tumors affecting up to 70% of reproductive-age women in the United States, significantly impacting productivity and quality of life. Despite their commonality, the epidemiology and clinical patterns of leiomyomas in Puerto Rico remain inadequately researched. Methods: This study conducted a secondary data analysis using clinical, menstrual cycle characteristics, and demographic data from self-administered questionnaires of women undergoing diagnostic laparoscopy for endometriosis in Puerto Rico. Chi-square tests and t-tests analyzed categorical and continuous variables, respectively (p Results: Among 1,610 endometriosis cases, 312 included uterine fibroids. Prevalence estimates were 10.3% (40 years). Primiparous women averaged 22.14 years, with 40.71% having 2 - 3 pregnancies and 26.28% experiencing miscarriages. Symptoms included infertility (29.5%), dyspareunia (40.7%), severe pain (50%), and dysmenorrhea (75.6%). Comorbidities included ovarian cysts (52.2%) and abnormal uterine bleeding (37.8%). Conclusions: Advanced age, parity, and comorbidities like diabetes and hypertension were prevalent in our cohort. Understanding the epidemiological profile of women living in Puerto Rico with uterine fibroids is crucial for improving diagnostic awareness and enhancing patient care.
文摘BACKGROUND Moyamoya disease is essentially an ischemic cerebrovascular disease.Here,we describe a case of acute recurrent cerebral infarction caused by moyamoya disease with concurrent adenomyosis which,to our knowledge,is the first in the literature.A literature review is also presented.CASE SUMMARY A 38-year-old female presented to the Research and Treatment Center of Moyamoya Disease in our hospital with"left limb weakness"as the main symptom.She was diagnosed with acute cerebral infarction and moyamoya disease through magnetic resonance imaging and digital subtraction angiography.Prior to this,she had experienced a prolonged menstrual period of one-month duration.This was investigated and adenomyosis was diagnosed.After passing the acute cerebral infarction phase,the patient underwent surgery for adenomyosis followed by combined cerebral revascularization.During the postoperative follow-up,improvements of the perfusion imaging stage and modified Rankin Scale were observed.A review of the literature showed only 16 reported cases of gynecological diseases complicated with stroke.The clinical characteristics,pathogenesis,therapeutic effects,and long-term prognosis of these cases have been studied and discussed.CONCLUSION In patients with moyamoya disease,early management of gynecological-related bleeding disorders is essential to prevent the complications of cerebral events.
文摘Objective:To explore the application of health education in the nursing care of patients with metrorrhagia and metrostaxis after hysteroscopic electrotomy and the effect on the occurrence of disease complications.Methods:Totally 70 patients admitted from March 2018 to March 2019 were randomly divided into two groups.The control group was given routine nursing,while the observation group was given comprehensive health education combined with routine nursing.The unhealthy emotions(anxiety and depression)of patients were assessed using Hamilton Depression Scale(HAMD)and Hamilton Anxiety Scale(HAMA).The incidence of complications,and surgical related matters were recorded and compared between two groups after nursing interventions.Results:A lower HAMD score,A lower HAMA score,a shorter hospitalization time,a shorter operation time and a less intraoperative bleeding volume,a lower incidence rate of complications(massive bleeding and uterine perforation),and a higher degree of patients’cooperation in surgery were shown in observation group compared with control group after nursing intervention(P all<0.05).Conclusion:The application of health education in the nursing of metrorrhagia and metrostaxis patients can relieve the patients’anxiety and depression,improve their understanding and mastery of relevant disease knowledge and their ability to cope with bleeding and their self-health care,as well as reduce the incidence of complications and the length of hospital stay and promote the rehabilitation of patients.Therefore,it is worthy of clinical application.
文摘BACKGROUND Atypical endometrial hyperplasia(AEH)is a common precancerous lesion of endometrial carcinoma(EC).The risk factors for AEH and EC directly or indirectly related to estrogen exposure include early menarche,nulliparity,polycystic ovarian syndrome,diabetes,and obesity.Both AEH and EC rarely occur in young patients(<40-years-old),who may desire to maintain their fertility.Evaluating the cancer risk of AEH patients is helpful for the determination of therapeutic plans.CASE SUMMARY We report a rare case of AEH in a 35-year-old woman who presented to the Hunan Provincial Maternal and Child Health Care Hospital with a large mass in the uterus.She married at 20-years-old,and had been married for more than 15 years to date.Several characteristics of this patient were observed,including nulliparity,limited sexual activity(intercourse 1-2 times a year)in recent years,and irregular vaginal bleeding for 2 years.Gynecological examination revealed an enlarged uterus,similar to the uterus size in the fourth month of pregnancy,and the uterine wall was relatively hard.Curettage was performed based on transvaginal sonography and magnetic resonance imaging results.Findings from the pathological examination were typical for AEH.The patient was cured after treatment with the standard therapy of high-dose progesterone.CONCLUSION In patients with intrauterine lumps that may be malignant,a pathological report should be obtained.
文摘Covid-19 was declared a global pandemic by the World Health Organization;it has caused more than 4</span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">,</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">697</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">,</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">099 deaths worldwide. Since the discovery of Vaccines, the rate of infections and deaths </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">are</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> declining in countries that were able to conduct mass vaccination, making the vaccines the most effect tool in the fight against Covid-19. However</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">,</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> there is still vaccination skepticism. The side effects </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">of </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">vaccines could fuel more skepticism.</span></span></span><span><span><span style="font-family:""> </span></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;">There are emerging possible new side effects such as abnormal uterine bleeding post Covid-19 vaccination, for which health care providers and the population should be aware. In this paper, we are reporting three (3) cases of abnormal uterine bleeding which seems to be linked to Covid-19 vaccines. We reported </span><span style="font-family:Verdana;">two incidents of heavy menstrual bleeding and one incident of inter-menstrual </span><span style="font-family:Verdana;">bleeding which are likely associated with COVID 19 vaccination, even though the causality c</span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">ould </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">not be confirmed. Also both type</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">s</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> of vaccines, Messenger RNA and Adenovirus vector could possibly be associated with abnormal uterine bleeding. As research is still ongoing, more knowledge would be available, meanwhile, healthcare providers and the population should be made aware of the new possible side effects of Covid-19 vaccines.
文摘For the treatment of premenstrual disease, it is particularly important to treat the spleen and kidney, because there are yin and yang in each viscera. Once the spleen yang is damaged, it can lead to premenstrual, while the kidney yang damage can also lead to the spleen yang damage, yang damage and yin damage, which will also lead to early menstrual cycle. However, if the time delay is longer, it will develop into metrorrhagia and metrostaxis. It is necessary to take corresponding measures and timely treatment.
