1.Introduction These comments are in reference to the article "Awareness, practice and views about integrating AYUSH in allopathic curricu- lum of allopathic doctors and interns in a tertiary care teaching hospit...1.Introduction These comments are in reference to the article "Awareness, practice and views about integrating AYUSH in allopathic curricu- lum of allopathic doctors and interns in a tertiary care teaching hospital in new Delhi,India,"published in Journal of Integrative Medicine in March 2018[1].展开更多
With growing antipathy toward conventional prescription drugs due to the fear of adverse events,the general and patient populations have been increasingly using complementary and alternative medications(CAMs)for manag...With growing antipathy toward conventional prescription drugs due to the fear of adverse events,the general and patient populations have been increasingly using complementary and alternative medications(CAMs)for managing acute and chronic diseases.The general misconception is that natural herbal-based preparations are devoid of toxicity,and hence short-and long-term use remain justified among people as well as the CAM practitioners who prescribe these medicines.In this regard,Ayurvedic herbal medications have become one of the most utilized in the East,specifically the Indian sub-continent,with increasing use in the West.Recent well-performed observational studies have confirmed the hepatotoxic potential of Ayurvedic drugs.Toxicity stems from direct effects or from indirect effects through herbal metabolites,unknown herb-herb and herbdrug interactions,adulteration of Ayurvedic drugs with other prescription medicines,and contamination due to poor manufacturing practices.In this exhaustive review,we present details on their hepatotoxic potential,discuss the mechanisms,clinical presentation,liver histology and patient outcomes of certain commonly used Ayurvedic herbs which will serve as a knowledge bank for physicians caring for liver disease patients,to support early identification and treatment of those who present with CAM-induced liver injury.展开更多
Naturopathy is a traditional health care science having its own concepts of health and healing rooting through nature.It is a non-pharmacological system of health care which derives its disease causing and health keep...Naturopathy is a traditional health care science having its own concepts of health and healing rooting through nature.It is a non-pharmacological system of health care which derives its disease causing and health keeping principles from fundamental natural elements(Panchamahabhutas)viz.Prithvi,Jala,Vayu,Agni,and Akash.The imbalance among these five elements individually or in respect to others creates disease and in turn also forms the basis of healing if such imbalances are corrected.This paper reviews the simple concepts of naturopathy referring to health and disease and contextualises them to the on-going pandemic which has affected the entire world.An extensive manual and digital search of the relevant literature was done related to naturopathy in order to compile the review.This review is important from the perspectives that in the current pandemic the cure is still not evident from any corner of the world and from any system of medicine.Therefore such simple health keeping strategies from naturopathy seem to be of much relevance.展开更多
Evidence based validation of the ethno-pharmacological claims on traditional medicine(TM) is the need of the day for its globalization and reinforcement. Combining the unique features of identifying biomarkers that ar...Evidence based validation of the ethno-pharmacological claims on traditional medicine(TM) is the need of the day for its globalization and reinforcement. Combining the unique features of identifying biomarkers that are highly conserved across species, this can offer an innovative approach to biomarker-driven drug discovery and development. TMs are an integral component of alternative health care systems. India has a rich wealth of TMs and the potential to accept the challenge to meet the global demand for them. Ayurveda, Yoga, Unani, Siddha and Homeopathy(AYUSH) medicine are the major healthcare systems in Indian Traditional Medicine. The plant species mentioned in the ancient texts of these systems may be explored with the modern scientific approaches for better leads in the healthcare. TM is the best sources of chemical diversity for finding new drugs and leads. Authentication and scientific validation of medicinal plant is a fundamental requirement of industry and other organizations dealing with herbal drugs. Quality control(QC) of botanicals, validated processes of manufacturing, customer awareness and post marketing surveillance are the key points, which could ensure the quality, safety and efficacy of TM. For globalization of TM, there is a need for harmonization with respect to its chemical and metabolite profiling, standardization, QC, scientific validation,documentation and regulatory aspects of TM. Therefore, the utmost attention is necessary for the promotion and development of TM through global collaboration and co-ordination by national and international programme.展开更多
文摘1.Introduction These comments are in reference to the article "Awareness, practice and views about integrating AYUSH in allopathic curricu- lum of allopathic doctors and interns in a tertiary care teaching hospital in new Delhi,India,"published in Journal of Integrative Medicine in March 2018[1].
文摘With growing antipathy toward conventional prescription drugs due to the fear of adverse events,the general and patient populations have been increasingly using complementary and alternative medications(CAMs)for managing acute and chronic diseases.The general misconception is that natural herbal-based preparations are devoid of toxicity,and hence short-and long-term use remain justified among people as well as the CAM practitioners who prescribe these medicines.In this regard,Ayurvedic herbal medications have become one of the most utilized in the East,specifically the Indian sub-continent,with increasing use in the West.Recent well-performed observational studies have confirmed the hepatotoxic potential of Ayurvedic drugs.Toxicity stems from direct effects or from indirect effects through herbal metabolites,unknown herb-herb and herbdrug interactions,adulteration of Ayurvedic drugs with other prescription medicines,and contamination due to poor manufacturing practices.In this exhaustive review,we present details on their hepatotoxic potential,discuss the mechanisms,clinical presentation,liver histology and patient outcomes of certain commonly used Ayurvedic herbs which will serve as a knowledge bank for physicians caring for liver disease patients,to support early identification and treatment of those who present with CAM-induced liver injury.
文摘Naturopathy is a traditional health care science having its own concepts of health and healing rooting through nature.It is a non-pharmacological system of health care which derives its disease causing and health keeping principles from fundamental natural elements(Panchamahabhutas)viz.Prithvi,Jala,Vayu,Agni,and Akash.The imbalance among these five elements individually or in respect to others creates disease and in turn also forms the basis of healing if such imbalances are corrected.This paper reviews the simple concepts of naturopathy referring to health and disease and contextualises them to the on-going pandemic which has affected the entire world.An extensive manual and digital search of the relevant literature was done related to naturopathy in order to compile the review.This review is important from the perspectives that in the current pandemic the cure is still not evident from any corner of the world and from any system of medicine.Therefore such simple health keeping strategies from naturopathy seem to be of much relevance.
基金Department of Biotechnology,Government of India,New Delhi,for financial support through Tata Innovation Fellowship (D.O.No.BT/HRD/35/01/04/2014) to Dr. Pulok K. Mukherjee
文摘Evidence based validation of the ethno-pharmacological claims on traditional medicine(TM) is the need of the day for its globalization and reinforcement. Combining the unique features of identifying biomarkers that are highly conserved across species, this can offer an innovative approach to biomarker-driven drug discovery and development. TMs are an integral component of alternative health care systems. India has a rich wealth of TMs and the potential to accept the challenge to meet the global demand for them. Ayurveda, Yoga, Unani, Siddha and Homeopathy(AYUSH) medicine are the major healthcare systems in Indian Traditional Medicine. The plant species mentioned in the ancient texts of these systems may be explored with the modern scientific approaches for better leads in the healthcare. TM is the best sources of chemical diversity for finding new drugs and leads. Authentication and scientific validation of medicinal plant is a fundamental requirement of industry and other organizations dealing with herbal drugs. Quality control(QC) of botanicals, validated processes of manufacturing, customer awareness and post marketing surveillance are the key points, which could ensure the quality, safety and efficacy of TM. For globalization of TM, there is a need for harmonization with respect to its chemical and metabolite profiling, standardization, QC, scientific validation,documentation and regulatory aspects of TM. Therefore, the utmost attention is necessary for the promotion and development of TM through global collaboration and co-ordination by national and international programme.
