Objective:To assess the complete vaccination coverage and timeliness of childhood vaccinations among Indigenous children in Peninsular Malaysia.Methods:The study utilized data from the 2022 Orang Asli Health Survey,a ...Objective:To assess the complete vaccination coverage and timeliness of childhood vaccinations among Indigenous children in Peninsular Malaysia.Methods:The study utilized data from the 2022 Orang Asli Health Survey,a cross-sectional survey conducted among a representative sample of Orang Asli in Peninsular Malaysia.A total of 68 villages were randomly selected from a pool of 853 villages,encompassing diverse geographic and sociodemographic contexts with a total of 15950 respondents Orang Asli successfully interviewed.However,this study only utilized data from surveyed children aged 12 to 59 months with a total of 1551 children included.Validated structured questionnaires were used to collect sociodemographic data and health status,with nurses verifying vaccination records.Children who received all nine primary vaccinations were defined as having complete vaccination while those who received vaccine within the recommended time were defined as having timely vaccination.Data analysis was conducted using IBM SPSS version 25.0,focusing on descriptive analyses of children's vaccination status.Results:The prevalence of overall complete vaccination among Indigenous children was 87.7%,while timely vaccination was only 40.3%.The prevalence of complete vaccination for Bacillus Calmette-Guérin(BCG),the first dose of hepatitis B,three doses of DTaP-IPV-Hib,and measles,mumps,and rubella(MMR)was above 95.0%,except for the second and third doses of hepatitis B.The prevalence of timely vaccination ranged from above 95.0%for vaccines given at birth,gradually decreasing with increasing age to 57.5%for the first dose of MMR.Moreover,the completion rates for three doses of DtaP-IPV-Hib and the initial dose of MMR surpassed 90%among Indigenous children aged 12-23 months,yet the timeliness remained at a moderate level.Conclusions:While the overall complete vaccination coverage among Indigenous children in Malaysia is relatively high,there are concerning disparities in the timeliness of vaccination,particularly as children age.展开更多
Background:The advancement of genomics has progressed in lightning speed over the past two decades.Numerous large-scale genome sequencing initiatives were announced,along with the rise of the holistic precision medici...Background:The advancement of genomics has progressed in lightning speed over the past two decades.Numerous large-scale genome sequencing initiatives were announced,along with the rise of the holistic precision medicine approach.However,the field of genomic medicine has now come to a bottleneck since genomic-phenomic interactions are not fully comprehended due to the complexity of the human systems biology and environmental influence,hence the emergence of human phenomics.Results:This review attempts to provide an overview of the potential advantages of investigating the human phenomics of indigenous populations and the challenges ahead.Conclusion:We believe that the indigenous populations serve as an ideal model to excavate our understanding of genomic-environmental-phenomics interactions.展开更多
Good morning,ladies and gentlemen,On behalf of the Asian Strategy&Leadership Institute or ASLI, I would like to thank the organizer for inviting me to speak. ASLI is the top think-tank in Malaysia,and we have been...Good morning,ladies and gentlemen,On behalf of the Asian Strategy&Leadership Institute or ASLI, I would like to thank the organizer for inviting me to speak. ASLI is the top think-tank in Malaysia,and we have been connecting the industry and the government since our inception 25years ago.展开更多
文摘Objective:To assess the complete vaccination coverage and timeliness of childhood vaccinations among Indigenous children in Peninsular Malaysia.Methods:The study utilized data from the 2022 Orang Asli Health Survey,a cross-sectional survey conducted among a representative sample of Orang Asli in Peninsular Malaysia.A total of 68 villages were randomly selected from a pool of 853 villages,encompassing diverse geographic and sociodemographic contexts with a total of 15950 respondents Orang Asli successfully interviewed.However,this study only utilized data from surveyed children aged 12 to 59 months with a total of 1551 children included.Validated structured questionnaires were used to collect sociodemographic data and health status,with nurses verifying vaccination records.Children who received all nine primary vaccinations were defined as having complete vaccination while those who received vaccine within the recommended time were defined as having timely vaccination.Data analysis was conducted using IBM SPSS version 25.0,focusing on descriptive analyses of children's vaccination status.Results:The prevalence of overall complete vaccination among Indigenous children was 87.7%,while timely vaccination was only 40.3%.The prevalence of complete vaccination for Bacillus Calmette-Guérin(BCG),the first dose of hepatitis B,three doses of DTaP-IPV-Hib,and measles,mumps,and rubella(MMR)was above 95.0%,except for the second and third doses of hepatitis B.The prevalence of timely vaccination ranged from above 95.0%for vaccines given at birth,gradually decreasing with increasing age to 57.5%for the first dose of MMR.Moreover,the completion rates for three doses of DtaP-IPV-Hib and the initial dose of MMR surpassed 90%among Indigenous children aged 12-23 months,yet the timeliness remained at a moderate level.Conclusions:While the overall complete vaccination coverage among Indigenous children in Malaysia is relatively high,there are concerning disparities in the timeliness of vaccination,particularly as children age.
文摘Background:The advancement of genomics has progressed in lightning speed over the past two decades.Numerous large-scale genome sequencing initiatives were announced,along with the rise of the holistic precision medicine approach.However,the field of genomic medicine has now come to a bottleneck since genomic-phenomic interactions are not fully comprehended due to the complexity of the human systems biology and environmental influence,hence the emergence of human phenomics.Results:This review attempts to provide an overview of the potential advantages of investigating the human phenomics of indigenous populations and the challenges ahead.Conclusion:We believe that the indigenous populations serve as an ideal model to excavate our understanding of genomic-environmental-phenomics interactions.
文摘Good morning,ladies and gentlemen,On behalf of the Asian Strategy&Leadership Institute or ASLI, I would like to thank the organizer for inviting me to speak. ASLI is the top think-tank in Malaysia,and we have been connecting the industry and the government since our inception 25years ago.
