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Opportunities and challenges of artificial intelligence-assisted endoscopy and high-quality data for esophageal squamous cell carcinoma
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作者 Ken Kurisaki Shinichiro Kobayashi +6 位作者 Taro Akashi Yasuhiko Nakao Masayuki Fukumoto Kaito Tasaki Tomohiko Adachi Susumu Eguchi Kengo Kanetaka 《World Journal of Gastrointestinal Oncology》 2026年第1期61-74,共14页
This review comprehensively summarized the potential of artificial intelligence(AI)in the management of esophageal cancer.It highlighted the significance of AI-assisted endoscopy in Japan where endoscopy is central to... This review comprehensively summarized the potential of artificial intelligence(AI)in the management of esophageal cancer.It highlighted the significance of AI-assisted endoscopy in Japan where endoscopy is central to both screening and diagnosis.For the clinical adaptation of AI,several challenges remain for its effective translation.The establishment of high-quality clinical databases,such as the National Clinical Database and Japan Endoscopy Database in Japan,which covers almost all cases of esophageal cancer,is essential for validating multimodal AI models.This requires rigorous external validation using diverse datasets,including those from different endoscope manufacturers and image qualities.Furthermore,endoscopists’skills significantly affect diagnostic accuracy,suggesting that AI should serve as a supportive tool rather than a replacement.Addressing these challenges,along with country-specific legal and ethical considerations,will facilitate the successful integration of multimodal AI into the management of esophageal cancer,particularly in endoscopic diagnosis,and contribute to improved patient outcomes.Although this review focused on Japan as a case study,the challenges and solutions described are broadly applicable to other high-incidence regions. 展开更多
关键词 artificial intelligence Esophageal cancer ENDOSCOPY Deep learning National database Clinical translation Multimodal artificial intelligence
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Harnessing artificial intelligence for the assessment of liver fibrosis and steatosis via multiparametric ultrasound
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作者 Nicholas Viceconti Silvia Andaloro +8 位作者 Mattia Paratore Sara Miliani Giulia D’Acunzo Giuseppe Cerniglia Fabrizio Mancuso Elena Melita Antonio Gasbarrini Laura Riccardi Matteo Garcovich 《World Journal of Gastroenterology》 2026年第2期59-76,共18页
Artificial intelligence(AI)is revolutionizing medical imaging,particularly in chronic liver diseases assessment.AI technologies,including machine learning and deep learning,are increasingly integrated with multiparame... Artificial intelligence(AI)is revolutionizing medical imaging,particularly in chronic liver diseases assessment.AI technologies,including machine learning and deep learning,are increasingly integrated with multiparametric ultrasound(US)techniques to provide more accurate,objective,and non-invasive evaluations of liver fibrosis and steatosis.Analyzing large datasets from US images,AI enhances diagnostic precision,enabling better quantification of liver stiffness and fat content,which are essential for diagnosing and staging liver fibrosis and steatosis.Combining advanced US modalities,such as elastography and doppler imaging with AI,has demonstrated improved sensitivity in identifying different stages of liver disease and distinguishing various degrees of steatotic liver.These advancements also contribute to greater reproducibility and reduced operator dependency,addressing some of the limitations of traditional methods.The clinical implications of AI in liver disease are vast,ranging from early detection to predicting disease progression and evaluating treatment response.Despite these promising developments,challenges such as the need for large-scale datasets,algorithm transparency,and clinical validation remain.The aim of this review is to explore the current applications and future potential of AI in liver fibrosis and steatosis assessment using multiparametric US,highlighting the technological advances and clinical relevance of this emerging field. 展开更多
关键词 artificial intelligence Multiparametric ultrasound LIVER FIBROSIS STEATOSIS Shear wave elastography Attenuation imaging Machine learning Deep learning
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Integrating artificial intelligence in the diagnostic pathway of duodenal gastrointestinal stromal tumors:A case report
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作者 Himanshu Agrawal Garima Dwivedi +3 位作者 Rahul Rohitaj Himanshu Tanwar Shailender Maurya Nikhil Gupta 《Artificial Intelligence in Gastroenterology》 2026年第1期36-43,共8页
BACKGROUND Gastrointestinal stromal tumors(GISTs)are rare mesenchymal neoplasms primarily originating in the stomach or small intestine.Duodenal GISTs are particularly uncommon,accounting for only a small fraction of ... BACKGROUND Gastrointestinal stromal tumors(GISTs)are rare mesenchymal neoplasms primarily originating in the stomach or small intestine.Duodenal GISTs are particularly uncommon,accounting for only a small fraction of GIST cases.These tumors often present with nonspecific symptoms,making early detection challenging.This case discusses a duodenal GIST misdiagnosed as pancreatic cancer due to obstructive jaundice.CASE SUMMARY A 40-year-old male with jaundice and abdominal symptoms underwent imaging,which suggested a malignant periampullary tumor.Preoperative misdiagnosis of pancreatic cancer was made,and surgery was performed.Postoperative histopathology confirmed a duodenal GIST.The role of artificial intelligence in the diagnostic pathway is explored,emphasizing its potential to differentiate between duodenal GISTs and other similar conditions using advanced imaging analysis.CONCLUSION Artificial intelligence in radiomic imaging holds significant promise in enhancing the diagnostic process for rare cancers like duodenal GISTs,ensuring timely and accurate treatment. 展开更多
关键词 Gastrointestinal stromal tumor DUODENUM artificial intelligence Radiomics Preoperative diagnosis
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Artificial intelligence and machine learning-driven advancements in gastrointestinal cancer:Paving the way for precision medicine
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作者 Chahat Suri Yashwant K Ratre +2 位作者 Babita Pande LVKS Bhaskar Henu K Verma 《World Journal of Gastroenterology》 2026年第1期14-36,共23页
Gastrointestinal(GI)cancers remain a leading cause of cancer-related morbidity and mortality worldwide.Artificial intelligence(AI),particularly machine learning and deep learning(DL),has shown promise in enhancing can... Gastrointestinal(GI)cancers remain a leading cause of cancer-related morbidity and mortality worldwide.Artificial intelligence(AI),particularly machine learning and deep learning(DL),has shown promise in enhancing cancer detection,diagnosis,and prognostication.A narrative review of literature published from January 2015 to march 2025 was conducted using PubMed,Web of Science,and Scopus.Search terms included"gastrointestinal cancer","artificial intelligence","machine learning","deep learning","radiomics","multimodal detection"and"predictive modeling".Studies were included if they focused on clinically relevant AI applications in GI oncology.AI algorithms for GI cancer detection have achieved high performance across imaging modalities,with endoscopic DL systems reporting accuracies of 85%-97%for polyp detection and segmentation.Radiomics-based models have predicted molecular biomarkers such as programmed cell death ligand 2 expression with area under the curves up to 0.92.Large language models applied to radiology reports demonstrated diagnostic accuracy comparable to junior radiologists(78.9%vs 80.0%),though without incremental value when combined with human interpretation.Multimodal AI approaches integrating imaging,pathology,and clinical data show emerging potential for precision oncology.AI in GI oncology has reached clinically relevant accuracy levels in multiple diagnostic tasks,with multimodal approaches and predictive biomarker modeling offering new opportunities for personalized care.However,broader validation,integration into clinical workflows,and attention to ethical,legal,and social implications remain critical for widespread adoption. 展开更多
关键词 artificial intelligence Gastrointestinal cancer Precision medicine Multimodal detection Machine learning
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Protocol for a global electronic Delphi on integrating artificial intelligence into solid organ transplantation
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作者 Rowan Abuyadek Sara A Ghitani +6 位作者 Ramy Shaaban Muhammad AbdelAziz Quoritem Mohammed S Foula Rodaina Osama Abdel Majid Manar Mokhtar Yasir Ahmed Mohammed Elhadi Amr Alnagar 《World Journal of Transplantation》 2026年第1期9-16,共8页
Artificial intelligence(AI)is increasingly recognized as a transformative force in the field of solid organ transplantation.From enhancing donor-recipient matching to predicting clinical risks and tailoring immunosupp... Artificial intelligence(AI)is increasingly recognized as a transformative force in the field of solid organ transplantation.From enhancing donor-recipient matching to predicting clinical risks and tailoring immunosuppressive therapy,AI has the potential to improve both operational efficiency and patient outcomes.Despite these advancements,the perspectives of transplant professionals-those at the forefront of critical decision-making-remain insufficiently explored.To address this gap,this study utilizes a multi-round electronic Delphi approach to gather and analyses insights from global experts involved in organ transplantation.Participants are invited to complete structured surveys capturing demographic data,professional roles,institutional practices,and prior exposure to AI technologies.The survey also explores perceptions of AI’s potential benefits.Quantitative responses are analyzed using descriptive statistics,while open-ended qualitative responses undergo thematic analysis.Preliminary findings indicate a generally positive outlook on AI’s role in enhancing transplantation processes,particularly in areas such as donor matching and post-operative care.These mixed views reflect both optimism and caution among professionals tasked with integrating new technologies into high-stakes clinical workflows.By capturing a wide range of expert opinions,the findings will inform future policy development,regulatory considerations,and institutional readiness frameworks for the integration of AI into organ transplantation. 展开更多
关键词 artificial intelligence Solid organ transplantation Electronic Delphi Expert consensus Donor matching Digital health
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Multimodal artificial intelligence integrates imaging,endoscopic,and omics data for intelligent decision-making in individualized gastrointestinal tumor treatment
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作者 Hui Nian Yi-Bin Wu +5 位作者 Yu Bai Zhi-Long Zhang Xiao-Huang Tu Qi-Zhi Liu De-Hua Zhou Qian-Cheng Du 《Artificial Intelligence in Gastroenterology》 2026年第1期1-19,共19页
Gastrointestinal tumors require personalized treatment strategies due to their heterogeneity and complexity.Multimodal artificial intelligence(AI)addresses this challenge by integrating diverse data sources-including ... Gastrointestinal tumors require personalized treatment strategies due to their heterogeneity and complexity.Multimodal artificial intelligence(AI)addresses this challenge by integrating diverse data sources-including computed tomography(CT),magnetic resonance imaging(MRI),endoscopic imaging,and genomic profiles-to enable intelligent decision-making for individualized therapy.This approach leverages AI algorithms to fuse imaging,endoscopic,and omics data,facilitating comprehensive characterization of tumor biology,prediction of treatment response,and optimization of therapeutic strategies.By combining CT and MRI for structural assessment,endoscopic data for real-time visual inspection,and genomic information for molecular profiling,multimodal AI enhances the accuracy of patient stratification and treatment personalization.The clinical implementation of this technology demonstrates potential for improving patient outcomes,advancing precision oncology,and supporting individualized care in gastrointestinal cancers.Ultimately,multimodal AI serves as a transformative tool in oncology,bridging data integration with clinical application to effectively tailor therapies. 展开更多
关键词 Multimodal artificial intelligence Gastrointestinal tumors Individualized therapy Intelligent diagnosis Treatment optimization Prognostic prediction Data fusion Deep learning Precision medicine
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Artificial intelligence in metabolic dysfunction-associated steatotic liver disease:Transforming diagnosis and therapeutic approaches
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作者 Pablo Guillermo Hernández-Almonacid Ximena Marín-Quintero 《World Journal of Gastroenterology》 2026年第2期77-89,共13页
Metabolic dysfunction-associated steatotic liver disease(MASLD)is an increasingly prevalent condition associated with hepatic complications and cardiovascular and renal events.Given its significant clinical impact,the... Metabolic dysfunction-associated steatotic liver disease(MASLD)is an increasingly prevalent condition associated with hepatic complications and cardiovascular and renal events.Given its significant clinical impact,the development of new strategies for early diagnosis and treatment is essential to improve patient outcomes.Over the past decade,the integration of artificial intelligence(AI)into gastroenterology has led to transformative advancements in medical practice.AI represents a major step towards personalized medicine,offering the potential to enhance diagnostic accuracy,refine prognostic assessments,and optimize treatment strategies.Its applications are rapidly expanding.This article explores the emerging role of AI in the management of MASLD,emphasizing its ability to improve clinical prediction,enhance the diagnostic performance of imaging modalities,and support histopathological confirmation.Additionally,it examines the development of AI-guided personalized treatments,where lifestyle modifications and close monitoring play a pivotal role in achieving therapeutic success. 展开更多
关键词 Metabolic dysfunction-associated steatotic liver disease artificial intelligence Machine learning Deep learning ULTRASONOGRAPHY Digital pathology Hepatocellular carcinoma Precision medicine
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Exploring artificial intelligence literacy’s role in healthy behaviors and mental health
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作者 Jaewon Lee Jennifer Allen Gyuhyun Choi 《World Journal of Psychiatry》 2026年第1期55-60,共6页
Healthy behavior has long been linked to mental health outcomes.However,the role of artificial intelligence(AI)literacy in shaping healthy behaviors and its potential impact on mental health remains underexplored.This... Healthy behavior has long been linked to mental health outcomes.However,the role of artificial intelligence(AI)literacy in shaping healthy behaviors and its potential impact on mental health remains underexplored.This paper presents a scoping review offering a novel perspective on the intersection of healthy behaviors,mental health,and AI literacy.By examining how individuals’understanding of AI influences their choices regarding nutrition and their susceptibility to mental health issues,the current study explores emerging trends in health behavior decision-making.This emphasizes the need for integrating AI literacy into mental health and health behaviors education,as well as the development of AI-driven tools to support healthier behavior choices.It highlights that individuals with low AI literacy may misinterpret or overly depend on AI guidance,resulting in maladaptive health choices,while those with high AI literacy may be more likely to engage reflectively and sustain positive behaviors.The paper outlines the importance of inclusive education,user-centered design,and community-based support systems to enhance AI literacy for digitally marginalized groups.AI literacy may be positioned as a key determinant of health equity,better allowing for interdisciplinary strategies that empower individuals to make informed,autonomous decisions that promote both physical and mental health. 展开更多
关键词 artificial intelligence literacy Mental health Healthy behavior Digital health education Technology acceptance
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Artificial intelligence in functional gastrointestinal disorders:From precision diagnosis to preventive healthcare
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作者 Yi-Nan Yan Jing-Qi Zeng Xia Ding 《Artificial Intelligence in Gastroenterology》 2026年第1期20-35,共16页
Functional gastrointestinal disorders(FGIDs),including irritable bowel syndrome(IBS),functional dyspepsia(FD),and gastroesophageal reflux disease(GERD),present persistent diagnostic and therapeutic challenges due to s... Functional gastrointestinal disorders(FGIDs),including irritable bowel syndrome(IBS),functional dyspepsia(FD),and gastroesophageal reflux disease(GERD),present persistent diagnostic and therapeutic challenges due to symptom heterogeneity and the absence of reliable biomarkers.Artificial intelligence(AI)enables the integration of multimodal data to enhance FGID management through precision diagnostics and preventive healthcare.This minireview summarizes recent advancements in AI applications for FGIDs,highlighting progress in diagnostic accuracy,subtype classification,personalized interventions,and preventive strategies inspired by the traditional Chinese medicine concept of“treating the undiseased”.Machine learning and deep learning algorithms have demonstrated value in improving IBS diagnosis,refining FD neuro-gastrointestinal subtyping,and screening for GERD-related complications.Moreover,AI supports dietary,psychological,and integrative medicine-based interventions to improve patient adherence and quality of life.Nonetheless,key challenges remain,including data heterogeneity,limited model interpretability,and the need for robust clinical validation.Future directions emphasize interdisciplinary collaboration,the development of multimodal and explainable AI models,and the creation of patientcentered platforms to facilitate a shift from reactive treatment to proactive prevention.This review provides a systematic framework to guide the clinical application and theoretical innovation of AI in FGIDs. 展开更多
关键词 artificial intelligence Functional gastrointestinal disorders Irritable bowel syndrome Functional dyspepsia Gastroesophageal reflux disease
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Ethical and legal risks with hierarchical regulation of artificial intelligence in China’s medical field
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作者 Xin Xing Hao Qiu 《History and Philosophy of Medicine》 2026年第1期22-31,共10页
Background:Medical artificial intelligence(MAI)is a synthesis of medical science and artificial intelligence development,serving as a crucial field in the current advancement and application of AI.In the process of de... Background:Medical artificial intelligence(MAI)is a synthesis of medical science and artificial intelligence development,serving as a crucial field in the current advancement and application of AI.In the process of developing medical AI,there may arise not only legal risks such as infringement of privacy rights and health rights but also ethical risks stemming from violations of the principles of beneficence and non-maleficence.Methods:To effectively address the damages caused by MAI in the future,it is necessary to establish a hierarchical governance system with MAI.This paper examines the systematic collection of local practices in China and the induction and integration of legal remedies for the damage of MAI.Results:To effectively address the ethical and legal challenges of medical artificial intelligence,a hierarchical regulatory system should be established,which based on the impact of intervention measures on natural rights and differences in intervention timing.This paper finally obtains a legal hierarchical governance system corresponding to the ethical risks and legal risks of MAI in China.Conclusion:The Chinese government has formed a multi-agent governance system based on the impact of risks on rights and the timing of legal intervention,which provides a reference for other countries to follow up on the research on MAI risk management. 展开更多
关键词 medical artificial intelligence ethical risks legal risks legal layered regulation
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Progress,Challenges,and China’s Role in Global Artificial Intelligence Governance
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作者 Lang Ping 《Contemporary World》 2025年第3期14-18,共5页
Artificial intelligence(AI)is a new arena for human technological development,and one of the most concerning global governance issues at present.In recent years,breakthroughs in generative AI technologies have been ma... Artificial intelligence(AI)is a new arena for human technological development,and one of the most concerning global governance issues at present.In recent years,breakthroughs in generative AI technologies have been made,and the prospects of large-scale application of AI technologies have become ever brighter,bringing us closer to the artificial general intelligence(AGI)that can enable machines to think and act like humans.As a strategic technology leading a new round of technological revolution and industrial transformation,AI offers enormous opportunities to advance human society,yet it also introduces significant security risks and challenges.How to maximize the development potential of AI at the global level while establishing an effective international governance framework has become a focus of global concern. 展开更多
关键词 artificial general intelligence agi technological revolution artificial general intelligence artificial intelligence human technological developmentand global governance artificial intelligence ai machines think act humansas
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The Future of Artificial Intelligence in the Face of Data Scarcity
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作者 Hemn Barzan Abdalla Yulia Kumar +4 位作者 Jose Marchena Stephany Guzman Ardalan Awlla Mehdi Gheisari Maryam Cheraghy 《Computers, Materials & Continua》 2025年第7期1073-1099,共27页
Dealing with data scarcity is the biggest challenge faced by Artificial Intelligence(AI),and it will be interesting to see how we overcome this obstacle in the future,but for now,“THE SHOW MUST GO ON!!!”As AI spread... Dealing with data scarcity is the biggest challenge faced by Artificial Intelligence(AI),and it will be interesting to see how we overcome this obstacle in the future,but for now,“THE SHOW MUST GO ON!!!”As AI spreads and transforms more industries,the lack of data is a significant obstacle:the best methods for teaching machines how real-world processes work.This paper explores the considerable implications of data scarcity for the AI industry,which threatens to restrict its growth and potential,and proposes plausible solutions and perspectives.In addition,this article focuses highly on different ethical considerations:privacy,consent,and non-discrimination principles during AI model developments under limited conditions.Besides,innovative technologies are investigated through the paper in aspects that need implementation by incorporating transfer learning,few-shot learning,and data augmentation to adapt models so they could fit effective use processes in low-resource settings.This thus emphasizes the need for collaborative frameworks and sound methodologies that ensure applicability and fairness,tackling the technical and ethical challenges associated with data scarcity in AI.This article also discusses prospective approaches to dealing with data scarcity,emphasizing the blend of synthetic data and traditional models and the use of advanced machine learning techniques such as transfer learning and few-shot learning.These techniques aim to enhance the flexibility and effectiveness of AI systems across various industries while ensuring sustainable AI technology development amid ongoing data scarcity. 展开更多
关键词 Data scarcity artificial intelligence application of artificial intelligence ethical considerations artificial general intelligence synthetic data
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Artificial sensory neurons and their applications
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作者 Jiale Shao Hongwei Ying +6 位作者 Peihong Cheng Lingxiang Hu Xianhua Wei Zongxiao Li Huanming Lu Zhizhen Ye Fei Zhuge 《Journal of Semiconductors》 2025年第1期108-128,共21页
With the rapid development of artificial intelligence(AI)technology,the demand for high-performance and energyefficient computing is increasingly growing.The limitations of the traditional von Neumann computing archit... With the rapid development of artificial intelligence(AI)technology,the demand for high-performance and energyefficient computing is increasingly growing.The limitations of the traditional von Neumann computing architecture have prompted researchers to explore neuromorphic computing as a solution.Neuromorphic computing mimics the working principles of the human brain,characterized by high efficiency,low energy consumption,and strong fault tolerance,providing a hardware foundation for the development of new generation AI technology.Artificial neurons and synapses are the two core components of neuromorphic computing systems.Artificial perception is a crucial aspect of neuromorphic computing,where artificial sensory neurons play an irreplaceable role thus becoming a frontier and hot topic of research.This work reviews recent advances in artificial sensory neurons and their applications.First,biological sensory neurons are briefly described.Then,different types of artificial neurons,such as transistor neurons and memristive neurons,are discussed in detail,focusing on their device structures and working mechanisms.Next,the research progress of artificial sensory neurons and their applications in artificial perception systems is systematically elaborated,covering various sensory types,including vision,touch,hearing,taste,and smell.Finally,challenges faced by artificial sensory neurons at both device and system levels are summarized. 展开更多
关键词 artificial sensory neurons artificial perception systems neuromorphic computing artificial intelligence
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Integration of AI with artificial sensory systems for multidimensional intelligent augmentation 被引量:1
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作者 Changyu Tian Youngwook Cho +3 位作者 Youngho Song Seongcheol Park Inho Kim Soo-Yeon Cho 《International Journal of Extreme Manufacturing》 2025年第4期35-54,共20页
Artificial sensory systems mimic the five human senses to facilitate data interaction between the real and virtual worlds.Accurate data analysis is crucial for converting external stimuli from each artificial sense in... Artificial sensory systems mimic the five human senses to facilitate data interaction between the real and virtual worlds.Accurate data analysis is crucial for converting external stimuli from each artificial sense into user-relevant information,yet conventional signal processing methods struggle with the massive scale,noise,and artificial sensory systems characteristics of data generated by artificial sensory devices.Integrating artificial intelligence(AI)is essential for addressing these challenges and enhancing the performance of artificial sensory systems,making it a rapidly growing area of research in recent years.However,no studies have systematically categorized the output functions of these systems or analyzed the associated AI algorithms and data processing methods.In this review,we present a systematic overview of the latest AI techniques aimed at enhancing the cognitive capabilities of artificial sensory systems replicating the five human senses:touch,taste,vision,smell,and hearing.We categorize the AI-enabled capabilities of artificial sensory systems into four key areas:cognitive simulation,perceptual enhancement,adaptive adjustment,and early warning.We introduce specialized AI algorithms and raw data processing methods for each function,designed to enhance and optimize sensing performance.Finally,we offer a perspective on the future of AI-integrated artificial sensory systems,highlighting technical challenges and potential real-world application scenarios for further innovation.Integration of AI with artificial sensory systems will enable advanced multimodal perception,real-time learning,and predictive capabilities.This will drive precise environmental adaptation and personalized feedback,ultimately positioning these systems as foundational technologies in smart healthcare,agriculture,and automation. 展开更多
关键词 artificialsensorysystem artificial intelligence SENSOR deep learning signal processing
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Recent Advances in Artificial Sensory Neurons:Biological Fundamentals,Devices,Applications,and Challenges
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作者 Shuai Zhong Lirou Su +4 位作者 Mingkun Xu Desmond Loke Bin Yu Yishu Zhang Rong Zhao 《Nano-Micro Letters》 SCIE EI CAS 2025年第3期168-216,共49页
Spike-based neural networks,which use spikes or action potentialsto represent information,have gained a lot of attention because of their high energyefficiency and low power consumption.To fully leverage its advantage... Spike-based neural networks,which use spikes or action potentialsto represent information,have gained a lot of attention because of their high energyefficiency and low power consumption.To fully leverage its advantages,convertingthe external analog signals to spikes is an essential prerequisite.Conventionalapproaches including analog-to-digital converters or ring oscillators,and sensorssuffer from high power and area costs.Recent efforts are devoted to constructingartificial sensory neurons based on emerging devices inspired by the biologicalsensory system.They can simultaneously perform sensing and spike conversion,overcoming the deficiencies of traditional sensory systems.This review summarizesand benchmarks the recent progress of artificial sensory neurons.It starts with thepresentation of various mechanisms of biological signal transduction,followed bythe systematic introduction of the emerging devices employed for artificial sensoryneurons.Furthermore,the implementations with different perceptual capabilitiesare briefly outlined and the key metrics and potential applications are also provided.Finally,we highlight the challenges and perspectives for the future development of artificial sensory neurons. 展开更多
关键词 artificial intelligence Emerging devices artificial sensory neurons Spiking neural networks Neuromorphic sensing
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Decoding Alexander the Great’s gastrointestinal cause of death using artificial wisdom:An artificial intelligence-human inquiry into a medical mystery
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作者 An-Lai Zhou Joelle Yee-Hui Chiang +2 位作者 Kai Siang Chan Nicole Tan Vishal G Shelat 《World Journal of Gastroenterology》 2025年第46期118-128,共11页
BACKGROUND ChatGPT was developed in November 2022 with studies showing its impressive performance in academic examinations,serving as a promising tool to answer questions even on controversial topics.Artificial intell... BACKGROUND ChatGPT was developed in November 2022 with studies showing its impressive performance in academic examinations,serving as a promising tool to answer questions even on controversial topics.Artificial intelligence(AI)achieving surface-level performance does not necessarily equate to a deep understanding of human cognition.The development of artificial wisdom,therefore,necessitates a shift from simply mimicking intelligent behavior to modeling the underlying mechanisms of human wisdom,including emotional understanding,ethical considerations,and contextual awareness.Several theories exist behind the death of Alexander the Great,but no definitive conclusion has been made.AIM To evaluate whether a hybrid approach,combining generative AI(ChatGPT)with human clinical judgment,can meaningfully reassess the cause of death of Alexander the Great.METHODS This is a cross-sectional study using ChatGPT(version 4 Pro).A search was performed with search terms describing the symptoms experienced by Alexander the Great and possible causes of his death:West Nile virus(WNV)encephalitis,poisoning,acute pancreatitis due to excessive alcohol consumption,typhoid fever,and malaria.The historical data and symptomatology were analyzed,weighing evidence and context in a manner akin to human wisdom.RESULTS The most likely cause of death of Alexander the Great,as generated by ChatGPT,was typhoid fever complicated by Guillain-Barrésyndrome(GBS).The hypothesis was based on the alignment between Alexander’s reported symptoms,such as prolonged high fever,severe abdominal pain,neurological decline,and the known clinical presentation of typhoid fever.However,after carefully reviewing the sources mentioned by ChatGPT,many did not back up the idea that typhoid caused GBS and instead pointed to Campylobacter jejuni as the more likely trigger.Other possible causes of death suggested by ChatGPT including acute pancreatitis from excessive alcohol consumption,infectious causes(WNV encephalitis,malaria),and poisoning were less likely.CONCLUSION While ChatGPT initially concluded typhoid fever with GBS as the most plausible cause of death,expert reappraisal of the sources and pathophysiology suggested that C.jejuni-associated GBS was more likely.This study exemplifies how incorporating AI’s pattern recognition with human scrutiny can yield responsible interpretations of historical records. 展开更多
关键词 artificial intelligence artificial wisdom GASTROINTESTINAL History ALEXANDER TYPHOID Campylobacter jejuni
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Comparison of ChatGPT-3.5 and GPT-4 as potential tools in artificial intelligence-assisted clinical practice in renal and liver transplantation
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作者 Chrysanthos D Christou Olga Sitsiani +5 位作者 Panagiotis Boutos Georgios Katsanos Georgios Papadakis Anastasios Tefas Vassilios Papalois Georgios Tsoulfas 《World Journal of Transplantation》 2025年第3期194-211,共18页
BACKGROUND Kidney and liver transplantation are two sub-specialized medical disciplines,with transplant professionals spending decades in training.While artificial intelligencebased(AI-based)tools could potentially as... BACKGROUND Kidney and liver transplantation are two sub-specialized medical disciplines,with transplant professionals spending decades in training.While artificial intelligencebased(AI-based)tools could potentially assist in everyday clinical practice,comparative assessment of their effectiveness in clinical decision-making remains limited.AIM To compare the use of ChatGPT and GPT-4 as potential tools in AI-assisted clinical practice in these challenging disciplines.METHODS In total,400 different questions tested ChatGPT’s/GPT-4 knowledge and decision-making capacity in various renal and liver transplantation concepts.Specifically,294 multiple-choice questions were derived from open-access sources,63 questions were derived from published open-access case reports,and 43 from unpublished cases of patients treated at our department.The evaluation covered a plethora of topics,including clinical predictors,treatment options,and diagnostic criteria,among others.RESULTS ChatGPT correctly answered 50.3%of the 294 multiple-choice questions,while GPT-4 demonstrated a higher performance,answering 70.7%of questions(P<0.001).Regarding the 63 questions from published cases,ChatGPT achieved an agreement rate of 50.79%and partial agreement of 17.46%,while GPT-4 demonstrated an agreement rate of 80.95%and partial agreement of 9.52%(P=0.01).Regarding the 43 questions from unpublished cases,ChatGPT demonstrated an agreement rate of 53.49%and partial agreement of 23.26%,while GPT-4 demonstrated an agreement rate of 72.09%and partial agreement of 6.98%(P=0.004).When factoring by the nature of the task for all cases,notably,GPT-4 demonstrated outstanding performance,providing a differential diagnosis that included the final diagnosis in 90%of the cases(P=0.008),and successfully predicting the prognosis of the patient in 100%of related questions(P<0.001).CONCLUSION GPT-4 consistently provided more accurate and reliable clinical recommendations with higher percentages of full agreements both in renal and liver transplantation compared with ChatGPT.Our findings support the potential utility of AI models like ChatGPT and GPT-4 in AI-assisted clinical practice as sources of accurate,individualized medical information and facilitating decision-making.The progression and refinement of such AI-based tools could reshape the future of clinical practice,making their early adoption and adaptation by physicians a necessity. 展开更多
关键词 artificial intelligence ChatGPT GPT-4 TRANSPLANTATION KIDNEY LIVER Clinical decision support Generative artificial intelligence
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The Development of Artificial Intelligence:Toward Consistency in the Logical Structures of Datasets,AI Models,Model Building,and Hardware?
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作者 Li Guo Jinghai Li 《Engineering》 2025年第7期13-17,共5页
The aim of this article is to explore potential directions for the development of artificial intelligence(AI).It points out that,while current AI can handle the statistical properties of complex systems,it has difficu... The aim of this article is to explore potential directions for the development of artificial intelligence(AI).It points out that,while current AI can handle the statistical properties of complex systems,it has difficulty effectively processing and fully representing their spatiotemporal complexity patterns.The article also discusses a potential path of AI development in the engineering domain.Based on the existing understanding of the principles of multilevel com-plexity,this article suggests that consistency among the logical structures of datasets,AI models,model-building software,and hardware will be an important AI development direction and is worthy of careful consideration. 展开更多
关键词 CONSISTENCY datasets model building ai models artificial intelligence ai explore potential directions HARDWARE artificial intelligence
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Artificial intelligence in acute appendicitis: A comprehensive review of machine learning and deep learning applications
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作者 Sami Akbulut Zeynep Kucukakcali Cemil Colak 《World Journal of Gastroenterology》 2025年第43期35-58,共24页
Acute appendicitis(AAp)remains one of the most common abdominal emergencies,requiring rapid and accurate diagnosis to prevent complications and unnecessary surgeries.Conventional diagnostic methods,including medical h... Acute appendicitis(AAp)remains one of the most common abdominal emergencies,requiring rapid and accurate diagnosis to prevent complications and unnecessary surgeries.Conventional diagnostic methods,including medical history,clinical assessment,biochemical markers,and imaging techniques,often present limitations in sensitivity and specificity,especially in atypical cases.In recent years,artificial intelligence(AI)has demonstrated remarkable potential in enhancing diagnostic accuracy through machine learning(ML)and deep learning(DL)models.This review evaluates the current applications of AI in both adult and pediatric AAp,focusing on clinical data-based models,radiological imaging analysis,and AI-assisted clinical decision support systems.ML models such as random forest,support vector machines,logistic regression,and extreme gradient boosting have exhibited superior diagnostic performance compared to traditional scoring systems,achieving sensitivity and specificity rates exceeding 90%in multiple studies.Additionally,DL techniques,particularly convolutional neural networks,have been shown to outperform radiologists in interpreting ultrasound and computed tomography images,enhancing diagnostic confidence.This review synthesized findings from 65 studies,demonstrating that AI models integrating multimodal data including clinical,laboratory,and imaging parameters further improved diagnostic precision.Moreover,explainable AI approaches,such as SHapley Additive exPlanations and local interpretable model-agnostic explanations,have facilitated model transparency,fostering clinician trust in AI-driven decision-making.This review highlights the advancements in AI for AAp diagnosis,emphasizing that AI is used not only to establish the diagnosis of AAp but also to differentiate complicated from uncomplicated cases.While preliminary results are promising,further prospective,multicenter studies are required for large-scale clinical implementation,given that a great proportion of current evidence derives from retrospective designs,and existing prospective cohorts exhibit limited sample sizes or protocol variability.Future research should also focus on integrating AI-driven decision support tools into routine emergency care workflows. 展开更多
关键词 Acute appendicitis Complicated appendicitis artificial intelligence Machine learning Deep learning Decision support systems Explainable artificial intelligence Predictive modeling DIAGNOSIS
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Artificial Intelligence and Engineering:Philosophical and Scientific Perspectives in the New Era
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作者 Refet Ramiz 《Philosophy Study》 2025年第5期195-215,共21页
In this work,a general definition,meaning,and importance of engineering are expressed generally,and the main branches of engineering are briefly discussed.The concept of technology is explored,and the relationship bet... In this work,a general definition,meaning,and importance of engineering are expressed generally,and the main branches of engineering are briefly discussed.The concept of technology is explored,and the relationship between engineering and technology is briefly outlined.The relationship between artificial intelligence and engineering is examined both generally and specifically.The place of artificial intelligence within science is evaluated according to different approaches.The general approach to philosophy and philosophy of science is briefly interpreted,and the perspectives of some specific philosophers of science are compared.The relationship between artificial intelligence and philosophy of science is examined in general terms according to various approaches.The meaning and importance of philosophy of engineering and philosophy of technology are then defined according to the general approach.The next section articulates the Philosophy of Artificial Intelligence and the Artificial Intelligence of Philosophy using John McCarthy's approach,and also defines the philosophy of artificial intelligence according to this general approach.The New Philosophy Perspective is then defined by the author,and the eight basic branches of Philosophy and Hybrid Philosophy,along with their relevant theories,are briefly outlined.A new perspective has been defined for Philosophy of Science which is one of the basic branches of philosophy.Accordingly,the main sciences,branches of science,and hybrid sciences for the new basic branches of philosophy have been outlined.The new branches of science and the corresponding hierarchy of sciences,based on the broader scale of the universe,have been defined,and the ideal scientific system has been illustrated.The next section briefly outlines the relationships between old and new branches of science.Finally,the structure of some old and new branches of philosophy is examined due to the new perspective of philosophy.The reconstructions of the Philosophy of Computer Science,Philosophy of Statistics,Philosophy of Monetary Values,Philosophy of Artificial Intelligence,Philosophy of Engineering,Philosophy of Information Technologies,Philosophy of Information Law,and Philosophy of Digital Technology,Philosophy of Digital Art,Philosophy of Architecture as defined by the new philosophical perspective,are outlined.The interaction of artificial intelligence philosophy with these branches of philosophy has been generally expressed. 展开更多
关键词 artificial intelligence ENGINEERING technology science Philosophy of Science Philosophy of artificial Intelligence Philosophy of Engineering New Era Philosophy Hybrid Philosophies Basic Philosophies
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