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ChatGPT in liver transplantation:Current applications,limitations,and future directions
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作者 Eleni Avramidou Nikolaos Kougianos +3 位作者 George Chiotis-Miehe Stella Vasileiadou Georgios Katsanos Georgios Tsoulfas 《World Journal of Transplantation》 2026年第1期75-81,共7页
Liver transplantation(LT)remains the optimal life-saving intervention for patients with end-stage liver disease.Despite the recent advances in LT several barriers,including organ allocation,donor-recipient matching,an... Liver transplantation(LT)remains the optimal life-saving intervention for patients with end-stage liver disease.Despite the recent advances in LT several barriers,including organ allocation,donor-recipient matching,and patient education,persist.With the growing progress of artificial intelligence,particularly large language models(LLMs)like ChatGPT,new applications have emerged in the field of LT.Current studies demonstrating usage of ChatGPT in LT include various areas of application,from clinical settings to research and education.ChatGPT usage can benefit both healthcare professionals,by decreasing the time spent on non-clinical work,but also LT recipients by providing accurate information.Future potential applications include the expanding usage of ChatGPT and other LLMs in the field of LT pathology and radiology as well as the automated creation of discharge summaries or other related paperwork.Additionally,the next models of ChatGPT might have the potential to provide more accurate patient education material with increased readability.Although ChatGPT usage presents promising applications,there are certain ethical and practical limitations.Key concerns include patient data privacy,information accuracy,misinformation possibility and lack of legal framework.Healthcare providers and policymakers should collaborate for the establishment of a controlled framework for the safe use of ChatGPT.The aim of this minireview is to summarize current literature on ChatGPT in LT,highlighting both opportunities and limitations,while also providing future possible applications. 展开更多
关键词 ChatGPT Liver transplantation applications LIMITATIONS Artificial intelligence Large language model
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Engineered Radiative Cooling Systems for Thermal-Regulating and Energy-Saving Applications
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作者 Leqi Lei Ting Wu +8 位作者 Shuo Shi Yifan Si Chuanwei Zhi Kaisong Huang Jieqiong Yang Xinshuo Liang Shanshan Zhu Jinping Qu Jinlian Hu 《Nano-Micro Letters》 2026年第1期509-544,共36页
Radiative cooling systems(RCSs)possess the distinctive capability to dissipate heat energy via solar and thermal radiation,making them suitable for thermal regulation and energy conservation applications,essential for... Radiative cooling systems(RCSs)possess the distinctive capability to dissipate heat energy via solar and thermal radiation,making them suitable for thermal regulation and energy conservation applications,essential for mitigating the energy crisis.A comprehensive review connecting the advancements in engineered radiative cooling systems(ERCSs),encompassing material and structural design as well as thermal and energy-related applications,is currently absent.Herein,this review begins with a concise summary of the essential concepts of ERCSs,followed by an introduction to engineered materials and structures,containing nature-inspired designs,chromatic materials,meta-structural configurations,and multilayered constructions.It subsequently encapsulates the primary applications,including thermal-regulating textiles and energy-saving devices.Next,it highlights the challenges of ERCSs,including maximized thermoregulatory effects,environmental adaptability,scalability and sustainability,and interdisciplinary integration.It seeks to offer direction for forthcoming fundamental research and industrial advancement of radiative cooling systems in real-world applications. 展开更多
关键词 Radiative cooling systems Engineered materials Thermal-regulating ENERGY-SAVING Smart applications
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Research progress on magnesium materials for structural,biomedical and energy applications
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作者 Yuanding Huang Domonkos Tolnai Norbert Hort 《Journal of Magnesium and Alloys》 2025年第8期3487-3489,共3页
Magnesium and its related materials have potential applications in the automotive sector for weight reduction,in energy storage technologies such as batteries and hydrogen storage,and in biomedical field due to their ... Magnesium and its related materials have potential applications in the automotive sector for weight reduction,in energy storage technologies such as batteries and hydrogen storage,and in biomedical field due to their biodegradability.In comparison,the researches on the latter ones are currently receiving more and more interests.This paper explores recent research advancements in Mg-based materials in these fields especially within recent 4 years in Germany. 展开更多
关键词 energy storage magnesium materials biomedical applications weight reductionin biomedical field structural applications hydrogen storage energy storage technologies
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Preface to Special Topic on Integrated Circuits, Technologies and Applications 2024
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作者 Zheng Wang Yan Lu 《Journal of Semiconductors》 2025年第6期6-7,共2页
This Special Topic of the Journal of Semiconductors(JOS)features expanded versions of key articles presented at the 2024 IEEE International Conference on Integrated Circuits Technologies and Applications(ICTA),which w... This Special Topic of the Journal of Semiconductors(JOS)features expanded versions of key articles presented at the 2024 IEEE International Conference on Integrated Circuits Technologies and Applications(ICTA),which was held in Hangzhou,Zhejiang,China,from October 25 to 27,2024. 展开更多
关键词 TECHNOLOGIES IEEE International Conference Integrated Circuits Technologies applications integrated circuits technologies integrated circuits ZHEJIANG expanded versions key articles journal semiconductors applications
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Recent applications of EEG-based brain-computer-interface in the medical field 被引量:6
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作者 Xiu-Yun Liu Wen-Long Wang +39 位作者 Miao Liu Ming-Yi Chen Tânia Pereira Desta Yakob Doda Yu-Feng Ke Shou-Yan Wang Dong Wen Xiao-Guang Tong Wei-Guang Li Yi Yang Xiao-Di Han Yu-Lin Sun Xin Song Cong-Ying Hao Zi-Hua Zhang Xin-Yang Liu Chun-Yang Li Rui Peng Xiao-Xin Song Abi Yasi Mei-Jun Pang Kuo Zhang Run-Nan He Le Wu Shu-Geng Chen Wen-Jin Chen Yan-Gong Chao Cheng-Gong Hu Heng Zhang Min Zhou Kun Wang Peng-Fei Liu Chen Chen Xin-Yi Geng Yun Qin Dong-Rui Gao En-Ming Song Long-Long Cheng Xun Chen Dong Ming 《Military Medical Research》 2025年第8期1283-1322,共40页
Brain-computer interfaces(BCIs)represent an emerging technology that facilitates direct communication between the brain and external devices.In recent years,numerous review articles have explored various aspects of BC... Brain-computer interfaces(BCIs)represent an emerging technology that facilitates direct communication between the brain and external devices.In recent years,numerous review articles have explored various aspects of BCIs,including their fundamental principles,technical advancements,and applications in specific domains.However,these reviews often focus on signal processing,hardware development,or limited applications such as motor rehabilitation or communication.This paper aims to offer a comprehensive review of recent electroencephalogram(EEG)-based BCI applications in the medical field across 8 critical areas,encompassing rehabilitation,daily communication,epilepsy,cerebral resuscitation,sleep,neurodegenerative diseases,anesthesiology,and emotion recognition.Moreover,the current challenges and future trends of BCIs were also discussed,including personal privacy and ethical concerns,network security vulnerabilities,safety issues,and biocompatibility. 展开更多
关键词 Brain-computer interfaces(BCIs) Medical applications REHABILITATION COMMUNICATION Brain monitoring DIAGNOSIS
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Liquid metal composites:Recent advances and applications 被引量:1
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作者 Chunghyeon Choi Liyang Liu Byungil Hwang 《International Journal of Minerals,Metallurgy and Materials》 2025年第5期1008-1024,共17页
Liquid metals(LMs),because of their ability to remain in a liquid state at room temperature,render them highly versatile for applications in electronics,energy storage,medicine,and robotics.Among various LMs,Ga-based ... Liquid metals(LMs),because of their ability to remain in a liquid state at room temperature,render them highly versatile for applications in electronics,energy storage,medicine,and robotics.Among various LMs,Ga-based LMs exhibit minimal cytotoxicity,low viscosity,high thermal and electrical conductivities,and excellent wettability.Therefore,Ga-based LM composites(LMCs)have emerged as a recent research focus.Recent advancements have focused on novel fabrication techniques and applications spanning energy storage,flexible electronics,and biomedical devices.Particularly noteworthy are the developments in wearable sensors and electronic skins,which hold promise for healthcare monitoring and human-machine interfaces.Despite their potential,challenges,such as oxidative susceptibil-ity and biocompatibility,remain.Creating bio-based LMC materials is a promising approach to address these issues while exploring new avenues to optimize LMC performance and broaden its application domains.This review provides a concise overview of the recent trends in LMC research,highlights their transformative impacts,and outlines key directions for future investigation and development. 展开更多
关键词 COMPOSITES liquid metal POLYMER applications ALLOYS
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A review on applications and challenges of carbon nanotubes in lithium-ion battery 被引量:1
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作者 Zhen Tong Chao Lv +3 位作者 Guo-Dong Bai Zu-Wei Yin Yao Zhou Jun-Tao Li 《Carbon Energy》 2025年第2期66-97,共32页
Carbon nanotubes(CNTs)have many excellent properties that make them ideally suited for use in lithium-ion batteries(LIBs).In this review,the recent research on applications of CNTs in LIBs,including their usage as fre... Carbon nanotubes(CNTs)have many excellent properties that make them ideally suited for use in lithium-ion batteries(LIBs).In this review,the recent research on applications of CNTs in LIBs,including their usage as freestanding anodes,conductive additives,and current collectors,are discussed.Challenges,strategies,and progress are analyzed by selecting typical examples.Particularly,when CNTs are used with relatively large mass fractions,the relevant interfacial electrochemistry in such a CNT-based electrode,which dictates the quality of the resulting solid-electrolyte interface,becomes a concern.Hence,in this review the different lithium-ion adsorption and insertion mechanisms inside and outside of CNTs are compared;the influence of not only CNT structural features(including their length,defect density,diameter,and wall thickness)but also the electrolyte composition on the solid-electrolyte interfacial reactions is analyzed in detail.Strategies to optimize the solid-solid interface between CNTs and the other solid components in various composite electrodes are also covered.By emphasizing the importance of such a structure-performance relationship,the merits and weaknesses of various applications of CNTs in various advanced LIBs are clarified. 展开更多
关键词 applications carbon nanotubes CHALLENGES energy storage lithium-ion batteries
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Particle Swarm Optimization: Advances, Applications, and Experimental Insights 被引量:1
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作者 Laith Abualigah 《Computers, Materials & Continua》 2025年第2期1539-1592,共54页
Particle Swarm Optimization(PSO)has been utilized as a useful tool for solving intricate optimization problems for various applications in different fields.This paper attempts to carry out an update on PSO and gives a... Particle Swarm Optimization(PSO)has been utilized as a useful tool for solving intricate optimization problems for various applications in different fields.This paper attempts to carry out an update on PSO and gives a review of its recent developments and applications,but also provides arguments for its efficacy in resolving optimization problems in comparison with other algorithms.Covering six strategic areas,which include Data Mining,Machine Learning,Engineering Design,Energy Systems,Healthcare,and Robotics,the study demonstrates the versatility and effectiveness of the PSO.Experimental results are,however,used to show the strong and weak parts of PSO,and performance results are included in tables for ease of comparison.The results stress PSO’s efficiency in providing optimal solutions but also show that there are aspects that need to be improved through combination with algorithms or tuning to the parameters of the method.The review of the advantages and limitations of PSO is intended to provide academics and practitioners with a well-rounded view of the methods of employing such a tool most effectively and to encourage optimized designs of PSO in solving theoretical and practical problems in the future. 展开更多
关键词 Particle swarm optimization(PSO) optimization algorithms data mining machine learning engineer-ing design energy systems healthcare applications ROBOTICS comparative analysis algorithm performance evaluation
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Structural color from basic principles to emerging applications
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作者 Dohyun Kang Junsuk Rho 《Opto-Electronic Advances》 2025年第4期1-3,共3页
Wenhao Wang and colleagues summarized the latest advancements in structural color research in Opto-Electronic Science. Their review explored the fundamental principles and fabrication methods of structural colors for ... Wenhao Wang and colleagues summarized the latest advancements in structural color research in Opto-Electronic Science. Their review explored the fundamental principles and fabrication methods of structural colors for photonic applications, including anti-counterfeiting, displays, sensors, and printing, along with their practical limitations. Recently, structural colors have received growing interest due to their advantages, including physical and chemical robustness, ecofriendliness, tunability, and high-resolution color. 展开更多
关键词 structural colors anti counterfeiting SENSORS DISPLAYS structural color nanofabrication PRINTING optical applications
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Immune cell-derived exosomal non-coding RNAs in tumor microenvironment:Biological functions and potential clinical applications
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作者 Chenguang Liu Yawen Luo +3 位作者 Huan Zhou Meixi Lin Dan Zang Jun Chen 《Chinese Journal of Cancer Research》 2025年第2期250-267,共18页
The intricate interactions between immune cells and tumors exert a profound influence on cancer progression and therapeutic efficacy.Within the tumor microenvironment,exosomes have emerged as pivotal mediators of inte... The intricate interactions between immune cells and tumors exert a profound influence on cancer progression and therapeutic efficacy.Within the tumor microenvironment,exosomes have emerged as pivotal mediators of intercellular communication,with their cargo of non-coding RNAs(ncRNAs)serving as key regulatory elements.This review examines the multifaceted roles of immune cell-derived exosomal ncRNAs in tumor biology.The involvement of various immune cells,including T cells,B cells,natural killer cells,macrophages,neutrophils,and myeloid-derived suppressor cells,in utilizing exosomal ncRNAs to regulate tumor initiation and progression is explored.Additionally,the biogenesis and delivery mechanisms of these immune cell-derived exosomal ncRNAs are discussed,alongside their potential clinical applications in cancer. 展开更多
关键词 TUMOR IMMUNE EXOSOME non-coding RNAs clinical applications
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Intelligent bionics:Concepts,research and applications
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作者 Jiangeng Huang Zhiyong Chang +3 位作者 Jiangtao Qi Timothy Jakobi Zhihui Zhang Luquan Ren 《Advanced Bionics》 2025年第2期152-155,共4页
Intelligence is the capacity of an entity to adjust to environmental changes and overcome challenges.Intelligence has for all of eternity been a quality exclusive only to living organisms until the emergence of artifi... Intelligence is the capacity of an entity to adjust to environmental changes and overcome challenges.Intelligence has for all of eternity been a quality exclusive only to living organisms until the emergence of artificial intelligence.Thus the term“intelligence”inherently carries a latent“bionic”connotation.In contrast to artificial intelligence,which focuses on replicating and extending human cognitive abilities,bionic intelligence draws inspiration from intelligent behaviors and functions across diverse living organisms to enable bionic systems with low energy consumption,advanced working efficiency and strong task adaptability. 展开更多
关键词 artificial intelligencewhich intelligent bionics concepts RESEARCH living organisms adjust environmental changes artificial intelligencethus applications
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Light Management in 2D Perovskite Toward High-Performance Optoelectronic Applications
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作者 Kailian Dong Tao Jiang +9 位作者 Guoyi Chen Hongsen Cui Shuxin Wang Shun Zhou Chen Wang Yi Yang Fang Yao Chen Tao Weijun Ke Guojia Fang 《Nano-Micro Letters》 2025年第6期128-142,共15页
Two-dimensional Dion-Jacobson(DJ)perovskite has garnered significant attention due to its superior responsivity and operation stability.However,efforts are predominantly focused on discovering new organic spacer to sy... Two-dimensional Dion-Jacobson(DJ)perovskite has garnered significant attention due to its superior responsivity and operation stability.However,efforts are predominantly focused on discovering new organic spacer to synthesize novel perovskites,while material-form-associated light management,which is crucial for enhancing the photodetector’s efficiency,is largely overlooked.Herein,we introduced surface light management strategy into DJ-type perovskite system by synthesizing surface-patterned BDAPbBr4(BPB,BDA=NH_(3)(CH_(2))_(4)NH_(3))microplates(MPs)using template-assisted space-confined method,which was further elucidated by theoretical optical simulation.By leveraging surface-patterned MPs to enhance light absorption,the BPB-based photodetectors(PDs)achieved remarkable photoresponse in ultraviolet region,marked by a high on/off ratio(~5000),superior responsivity(2.24 A W^(-1)),along with large detectivity(~10^(13) Jones)and low detection limit(68.7 nW cm^(-2)).Additionally,the PDs showcased superior light communication and imaging capabilities even under weak-light illumination.Notably,the anisotropic nature of the surface-patterned MPs conferred excellent polarization sensitivity to the PD.These results represented the first demonstration of BPB perovskite in weak-light communication and imaging,as well as in polarized light detection.Our findings offer valuable insights into enhancing photodetector performance and optoelectronic applications through surface light management strategies. 展开更多
关键词 Light management Dion-Jacobson perovskite Surface-patterned Optoelectronic applications Polarization-sensitive
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echno-Functional Properties and Potential Applications of Peptides from Agro-Industrial Residues
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作者 Chaichawin Chavapradit Wonnop Visessanguan +1 位作者 Suwan Panjanapongchai Anil Kumar Anal 《Journal of Renewable Materials》 2025年第3期553-582,共30页
The growing population and industrialization have led to significant production in agro-industrial sectors,result-ing in large amounts of agro-industrial residues often left untreated,posing potential environmental is... The growing population and industrialization have led to significant production in agro-industrial sectors,result-ing in large amounts of agro-industrial residues often left untreated,posing potential environmental issues.There-fore,finding effective ways to utilize these bio-based residues is crucial.One promising approach is to use these low-or no-value agro-industrial wastes as raw materials for producing renewable biomaterials,including proteins and peptides.Research has extensively explored peptide extraction using plant and animal-based agro-industrial residue.Due to lower processing costs and beneficial bioactive properties,peptides derived from waste could replace synthetic peptides and those extracted from food sources.The isolation,purification,and analysis processes of these peptides are thoroughly examined to optimize their extraction and ensure their purity and efficacy.These peptides’bioactive properties and mechanisms are being analyzed for their potential applications in the biomedical field.Additionally,the applications of bioactive peptides in medical fields,such as drug delivery systems,tissue engineering,and bioprinting,are discussed. 展开更多
关键词 PEPTIDES techno-functional properties BIOREFINERY agro-industrial residues biomedical applications
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Magnesium alloys with rare-earth elements:Research trends applications,and future prospect
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作者 Zhiqi Zhu Irfan Ayoub +7 位作者 Jie He Jingran Yang HanDong Zhang Zhiqin Zhu Qi Hao Ziming Cai Oluwafunmilola Ola Santosh K.Tiwari 《Journal of Magnesium and Alloys》 2025年第8期3524-3563,共40页
Magnesium alloys have emerged as promising light weight materials due to their low density,high specific strength,excellent machinability,and superior damping capacity,making them ideal for aerospace,automotive,and el... Magnesium alloys have emerged as promising light weight materials due to their low density,high specific strength,excellent machinability,and superior damping capacity,making them ideal for aerospace,automotive,and electronics applications.However,broader use of magnesium alloys is limited by poor thermo-mechanical performance,corrosion susceptibility,and low formability at room temperature.The addition of rare-earth elements such as gadolinium,yttrium,and neodymium has meaningfully improved these limitations,enhancing the overall performance of magnesium alloys.This review highlights recent advancements in rare-earth magnesium alloys,focusing on their improved thermo-mechanical properties,microstructural evolution,crystallization behavior,and texture development.Herein,strengthening mechanisms associated with rare-earth additions are discussed in detail.Furthermore,the article explores growing relevance of these alloys in advanced applications,including biomedical implants,Io T devices,aerospace structures,defense systems,and general engineering.With their enhanced mechanical and functional properties,rare-earth magnesium alloys represent a new generation of high-performance,functional materials poised to drive innovation across multiple technology sectors. 展开更多
关键词 Rare-earth magnesium alloys Deformation mechanisms MICROSTRUCTURE Mechanical properties Thermal properties Crystallization processes applications
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Controllable synthesis and heterogeneous tailoring of 1D perovskites,emerging properties and applications
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作者 En Yang Mengna Zhang +6 位作者 Shuaishuai Wei Dan Liang Mustafa Zeb Liping Zhang Yoonseob Kim Yuan Zhao Wei Ma 《Advanced Powder Materials》 2025年第1期21-55,共35页
One-dimensional perovskites possess unique photoelectric properties that distinguish them from other perovskitetypes, making them a focal point in photoelectric research. In recent years, there has been a significant ... One-dimensional perovskites possess unique photoelectric properties that distinguish them from other perovskitetypes, making them a focal point in photoelectric research. In recent years, there has been a significant surge ininterest surrounding the synthesis and application of one-dimensional anisotropic perovskites, spurred by ad-vancementsin synthesis techniques and notable breakthroughs in novel methodologies and application proper-ties.This article provides a comprehensive review of the progress made in research on one-dimensionalanisotropic perovskites, detailing the synthesis mechanisms and potential pathways for performance enhance-mentin various applications. We highlight the crucial role of controllable synthesis and heterogeneous effect intailoring perovskite properties to boost application efficacy. Initially, this review examines the primary synthesismethods and mechanisms for creating heterogeneously induced one-dimensional anisotropic perovskites, cate-gorizingthem into two main approaches: the classical wet chemical synthesis, which utilizes selective ligands, andthe ligand-free, substrate-assisted method. The precision in controllable synthesis is essential for fabricatingheterogeneous structures, where the synthesized precursor, shape, and surface ligand significantly influence theinterfacial strength of the heterogenic interface. We also discuss the key features that must be improved for high-performanceapplications, exploring how heterogeneous effects can enhance performance and drive the devel-opmentof heterogeneous devices in various applications, such as photodetectors, solar cells, light-emitting di-odes,and photocatalysis. Conclusively, by highlighting the emerging potential and promising opportunitiesoffered by strategic heterogeneous construction, we forecast a dynamic and transformative future for their pro-ductionand application landscapes. 展开更多
关键词 One-dimensional perovskite Heterogeneous tailoring Controllable synthesis Stability Emerging applications
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Phase Transformation Behavior and Smart Applications of Shape Memory Alloys
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作者 Jiao Luo 《控制工程期刊(中英文版)》 2025年第2期7-11,共5页
Shape memory alloys(SMAs)are unique materials that exhibit the ability to recover their original shape upon heating after being deformed at low temperatures.Due to their remarkable properties,such as high strength,exc... Shape memory alloys(SMAs)are unique materials that exhibit the ability to recover their original shape upon heating after being deformed at low temperatures.Due to their remarkable properties,such as high strength,excellent fatigue resistance,and the ability to undergo significant recoverable deformation,SMAs have found extensive applications in various fields,including biomedical devices,robotics,aerospace,automotive industries,and smart textiles.This paper provides a comprehensive overview of the phase transformation behavior and smart applications of SMAs,focusing on the underlying mechanisms,characteristics,and technological advancements in SMA-based devices.It explores the various phases involved in SMA behavior,including the martensitic and austenitic phases,thermoelastic transformations,and stress-induced phase transformations.Furthermore,this paper discusses the applications of SMAs in smart technologies,including their use in medical devices,actuators,sensors,and energy harvesting systems.By exploring the key factors influencing phase transformations,this study highlights the potential of SMAs in designing next-generation smart materials and systems. 展开更多
关键词 Shape Memory Alloys Phase Transformation Martensitic Phase Austenitic Phase Smart applications Biomedical Devices Actuators SENSORS Energy Harvesting
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Thiolated nanomaterials for bone tissue engineering:synthesis,mechanisms,and applications
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作者 Yi-Ning Gong Bin Zhu +4 位作者 Ya-Zhong Bu Bao-Ji Du Shi-Chang Liu Lei Luo Liang Yan 《Rare Metals》 2025年第7期4346-4375,共30页
Owing to their unique biological effects and physicochemical properties,nanomaterials have garnered substantial attention in the field of bone tissue engineering(BTE),targeting the repair and restoration of impaired b... Owing to their unique biological effects and physicochemical properties,nanomaterials have garnered substantial attention in the field of bone tissue engineering(BTE),targeting the repair and restoration of impaired bone tissue.In recent years,strategies for the design and optimization of nanomaterials through thiolation modification have been widely applied in BTE.This review concisely summarizes the categories of nanomaterials commonly used in BTE and focuses on various strategies for the modification of nanomaterials via thiolation.A multifaceted analysis of the mechanisms by which thiolated nanomaterials enhance nanomaterial-cell interactions,promote drug loading and release,and modulate osteogenic differentiation is presented.Furthermore,this review introduces biomedical applications of thiolated nanomaterials in BTE,including as scaffold components for bone regeneration,coatings for bone implants,and drug delivery systems.Finally,the future perspectives and challenges in the development of this field are discussed.Thiolation modification strategies provide a platform for developing new ideas and methods for designing nanomaterials for BTE and are expected to accelerate the development and clinical translation of novel bone repair materials. 展开更多
关键词 Bone tissue engineering NANOMATERIALS THIOLATION Bone regeneration Biomedical applications
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Structure-function insights of natural Ganoderma polysaccharides:advances in biosynthesis and functional food applications
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作者 Zhou-Wei Wu Xue-Fang Zhao +5 位作者 Chen-Xi Quan Xiao-Cui Liu Xin-Yu Tao Yu-jie Li Xing-Rong Peng Ming-Hua Qiu 《Natural Products and Bioprospecting》 2025年第2期143-175,共33页
Ganoderma polysaccharides(GPs),derived from various species of the Ganoderma genus,exhibit diverse bioactivities,including immune modulation,anti-tumor effects,and gut microbiota regulation.These properties position G... Ganoderma polysaccharides(GPs),derived from various species of the Ganoderma genus,exhibit diverse bioactivities,including immune modulation,anti-tumor effects,and gut microbiota regulation.These properties position GPs as dual-purpose agents for medicinal and functional food development.This review comprehensively explores the structural complexity of six key GPs and their specific mechanisms of action,such as TLR signaling in immune modulation,apoptosis pathways in anti-tumor activity,and their prebiotic effects on gut microbiota.Additionally,the structure-activity relationships(SARs)of GPs are highlighted to elucidate their biological efficacy.Advances in green extraction techniques,including ultrasonic-assisted and enzymatic methods,are discussed for their roles in enhancing yield and aligning with sustainable production principles.Furthermore,the review addresses biotechnological innovations in polysaccharide biosynthesis,improving production efficiency and making large-scale production feasible.These insights,combined with ongoing research into their bioactivity,provide a solid foundation for developing health-promoting functional food products that incorporate GPs.Furthermore,future research directions are suggested to optimize biosynthesis pathways and fully harness the health benefits of these polysaccharides. 展开更多
关键词 Ganoderma polysaccharides extraction techniques structural characteristics Bioactivity biosynthetic pathways Functional food applications
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Inspired by nature:Bioinspired and biomimetic photocatalysts for biomedical applications
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作者 Ashkan Bigham Atefeh Zarepour +5 位作者 Moein Safarkhani YunSuk Huh Arezoo Khosravi Navid Rabiee Siavash Iravani Ali Zarrabi 《Nano Materials Science》 2025年第1期1-23,共23页
The field of photocatalysis has witnessed a significant advancement in the development of bioinspired and biomimetic photocatalysts for various biomedical applications,including drug delivery,tissue engineering,cancer... The field of photocatalysis has witnessed a significant advancement in the development of bioinspired and biomimetic photocatalysts for various biomedical applications,including drug delivery,tissue engineering,cancer therapy,and bioimaging.Nature has evolved efficient light-harvesting systems and energy conversion mechanisms,which serve as a benchmark for researchers.However,reproducing such complexity and harnessing it for biomedical applications is a daunting task.It requires a comprehensive understanding of the underlying biological processes and the ability to replicate them synthetically.By utilizing light energy,these photocatalysts can trigger specific chemical reactions,leading to targeted drug release,enhanced tissue regeneration,and precise imaging of biological structures.In this context,addressing the stability,long-term performance,scalability,and costeffectiveness of these materials is crucial for their widespread implementation in biomedical applications.While challenges such as complexity and stability persist,their advantages such as targeted drug delivery and personalized medicine make them a fascinating area of research.The purpose of this review is to provide a comprehensive analysis and evaluation of existing research,highlighting the advancements,current challenges,advantages,limitations,and future prospects of bioinspired and biomimetic photocatalysts in biomedicine. 展开更多
关键词 Bioinspired photocatalysts Nanophotocatalysts Biomedical applications Biomimetic photocatalysts Environmentally-benign strategies
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Exploring the expensive therapeutic potential and clinical applications of viruses severe acute respiratory syndrome(SARS)-COV-2
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作者 Abdul Bari Hejran Atiqullah Sarwari +5 位作者 Mohammad Hassan Hassand Abdul Wahid Monib Parwiz Niazi Abdul Qadeer Baseer Sayedwali Sediqi Uzair Mohammad Kakar 《Life Research》 2025年第1期6-15,共10页
In this review research,the full bio-medical potential and application of the severe acute respiratory syndrome(SARS)-CoV-2 viruses are discussed in detail with the aim of discovering innovative treatment strategies i... In this review research,the full bio-medical potential and application of the severe acute respiratory syndrome(SARS)-CoV-2 viruses are discussed in detail with the aim of discovering innovative treatment strategies in virology and medicine.The SARS-CoV-2 which caused an international health crisis also unraveled an opportunity to gain from its pathogenic effects to treat the affected people.The study aims at testing whether the newly discovered SARS-CoV-2 can be used for therapeutic and clinical purposes.With in-depth analytics,this investigation issue endeavors to unearth new ways of fighting infectious diseases and to improve existing medical interventions.Beside scientific and practical significance the role of this work is vital.By learning the biologic and molecular mysteries of SARS-CoV-2,the researchers can create precise medicines and vaccines not only against COVID-19 but also the other infectious diseases as well.Furthermore,this recommendation may open the door to the future development of gene therapy and vaccine technology.In this sense,it combines multiple approaches,such as viral studies,immunology,and molecular biology.Laboratory experiments,computer program modeling and clinical trials are applied to detection of the SARS-COV-2 in therapeutic implementation.The principal conclusion and analysis of this research put forth the fact that SARS-CoV-2 can be utilized in anti-viral treatment,cancer therapy,and vaccine programs.The study results confirm the inherent adaptability of viruses like SARS-CoV-2 and emphasis on the development of specific therapeutic measures.It is valuable because of its potential to add to virology and medication,showing new ways for virus-based treatment.In addition,the impact of these results on treatments would be revolutionary,with potential to invent superior and flexible interventions against infectious disease.In short,the therapeutic use of SARS-CoV-2 can be regarded as a bold innovation with tremendous consequences for general health,and ultimately for medical science. 展开更多
关键词 virus-based therapeutics SARS-CoV-2 repurposing clinical applications therapeutic potential TARGETED antiviral strategies medical interventions
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