伴随RESTful API在现代Web服务中的普及,安全问题日益凸显。而现有的主流API识别与漏洞检测工具依赖API文档或公开路径进行扫描,在识别隐藏API或无文档API时效果有限,在复杂或动态API环境下漏洞误报率高。针对这些挑战,基于上下文协议(M...伴随RESTful API在现代Web服务中的普及,安全问题日益凸显。而现有的主流API识别与漏洞检测工具依赖API文档或公开路径进行扫描,在识别隐藏API或无文档API时效果有限,在复杂或动态API环境下漏洞误报率高。针对这些挑战,基于上下文协议(MCP)无缝通信智能体,提出一种隐藏API发现和漏洞检测的智能体系统A2A(Agent to API vulnerability detection)来实现从API发现到漏洞检测的全流程自动化。A2A通过自适应枚举和HTTP响应分析自动识别潜在的隐藏API端点,并结合服务特定的API指纹库进行隐藏API的确认和发现。A2A在API漏洞检测上则是结合大语言模型(LLM)与检索增强生成(RAG)技术,并通过反馈迭代优化策略,自动生成高质量测试用例以验证漏洞是否存在。实验评估结果表明,A2A的平均API发现率为91.9%,假发现率为7.8%,并成功发现NAUTILUS和RESTler未能检测到的多个隐藏API漏洞。展开更多
Capillary electrophoresis(CE),recognized for its minimal reagent dosage,rapid analysis,and high efficiency,holds significant promise for the analysis of traditional Chinese medicines(TCM).This article reviews the appl...Capillary electrophoresis(CE),recognized for its minimal reagent dosage,rapid analysis,and high efficiency,holds significant promise for the analysis of traditional Chinese medicines(TCM).This article reviews the application of CE in the determination of active ingredients in TCM.The active substances of herbal medicines have been classified and discussed based on their chemical properties,and the CE methods applied to different substances are summarized and discussed.This article also provides some suggestions for future research and improvement.展开更多
Objective:To explore the application of external application of Traditional Chinese Medicine(TCM)hot compress package combined with Kinesio Taping in postoperative nursing of total knee arthroplasty.Methods:90 patient...Objective:To explore the application of external application of Traditional Chinese Medicine(TCM)hot compress package combined with Kinesio Taping in postoperative nursing of total knee arthroplasty.Methods:90 patients with severe knee osteoarthritis who underwent total knee arthroplasty in our department from January to December 2022 were randomly divided into two groups using a random number table method:one group was named the conventional group(n=45),which received the standard orthopedic nursing process throughout,including basic pain management,incision care,and functional exercise guidance;the other group was defined as the experimental group(n=45),which,in addition to the conventional nursing framework,incorporated the local transdermal drug delivery technique of TCM hot compress package and the biomechanical correction scheme of Kinesio Taping for collaborative intervention.Finally,the differences in postoperative resting/active pain scores(VAS)of the affected limb and satisfaction with nursing services between the two groups were compared using quantitative assessment tools.Results:The satisfaction with nursing care in the conventional group was significantly lower than that in the experimental group(P<0.05);the VAS score after nursing in the conventional group was significantly higher than that in the experimental group(P<0.05).Conclusion:The application of external application of TCM hot compress package combined with Kinesio Taping in postoperative nursing of total knee arthroplasty has a definite effect,reducing pain and improving patient satisfaction with nursing services.展开更多
Whole Slide Imaging (WSI) technology, as a revolutionary digital technology in the field of pathology, is gradually changing the traditional clinical pathological diagnosis model. By converting traditional glass patho...Whole Slide Imaging (WSI) technology, as a revolutionary digital technology in the field of pathology, is gradually changing the traditional clinical pathological diagnosis model. By converting traditional glass pathological sections into complete digital images through high-resolution scanning, it provides a new method for pathological diagnosis. Based on this, this paper studies the application of WSI technology in clinical pathological diagnosis, elaborates on its application value, analyzes the current application status, and proposes corresponding application countermeasures, aiming to provide reference for the standardized and popularized development of this technology in clinical pathological diagnosis.展开更多
Environmental DNA(eDNA)technology has revolutionized biodiversity monitoring with its non-invasive,sensitive,and cost-efficient approach.This paper systematically reviews eDNA advancements,examining its applications i...Environmental DNA(eDNA)technology has revolutionized biodiversity monitoring with its non-invasive,sensitive,and cost-efficient approach.This paper systematically reviews eDNA advancements,examining its applications in aquatic and terrestrial ecosystems and assessing China’s standardization progress.It delineates four developmental phases from single-species detection to high-throughput sequencing,and highlights China’s contribution to the development of technical standards.While significant progress has been made,challenges persist in quantitative accuracy,methodological consistency,and large-scale implementation.Future efforts should prioritize enhanced standardization,improved quantification techniques,broader applications,and international collaboration to drive innovation in eDNA technology.展开更多
Lignin,the most abundant natural aromatic polymer globally,has garnered considerable interest due to its rich and diverse active functional groups and its antioxidant,antimicrobial,and adhesive properties.Recent resea...Lignin,the most abundant natural aromatic polymer globally,has garnered considerable interest due to its rich and diverse active functional groups and its antioxidant,antimicrobial,and adhesive properties.Recent research has significantly improved the performance of lignin-based hydrogels,suggesting their substantial potential in fields such as biomedicine,environmental science,and agriculture.This paper reviews the process of lignin extraction,systematically introduces synthesis strategies for preparing lignin-based hydrogels,and discusses the current state of research on these hydrogels in biomedical and environmental protection fields.It concludes by identifying the existing challenges in lignin hydrogel research and envisioning future prospects and development trends.展开更多
Biomass is a resourcewhose organic carbon is formed from atmospheric carbon dioxide.It has numerous characteristics such as low carbon emissions,renewability,and environmental friendliness.The efficient utilization of...Biomass is a resourcewhose organic carbon is formed from atmospheric carbon dioxide.It has numerous characteristics such as low carbon emissions,renewability,and environmental friendliness.The efficient utilization of biomass plays a significant role in promoting the development of clean energy,alleviating environmental pressures,and achieving carbon neutrality goals.Among the numerous processing technologies of biomass,hydrothermal carbonization(HTC)is a promising thermochemical process that can decompose and convert biomass into hydrochar under relatively mild conditions of approximately 180℃–300℃,thereby enabling its efficient resource utilization.In addition,HTC can directly process feedstocks with high moisture content without the need for high-temperature drying,resulting in lower energy consumption.Based on a systematic analysis of the critical articles mainly published in 2011-2025 related to biomass,HTC,and hydrochar applications,in this review,the category of biomass was first classified and the chemical compositions were summarized.Then,the main chemical reaction pathways involved in biomass decomposition and transformation during the HTC process were introduced.Meanwhile,the roles of key process parameters,including reaction temperature,residence time,pH,feedstock type,pressure,mass ratio of biomass to water,and the use of catalysts on HTC,were carefully discussed.Finally,the applications of hydrochar in energy utilization,environmental remediation,soil improvement,adsorbent,microbial fermentation,and phosphorus recovery fields were highlighted.The future directions of the HTC process were also provided,which would respond to climate change by promoting the development of the sustainable carbon materials field.展开更多
The genus Actinidia is primarily functionally dioecious,and early sex identification plays a crucial role in improving breeding efficiency and reducing production costs.In this study,the accuracy of three sex-linked m...The genus Actinidia is primarily functionally dioecious,and early sex identification plays a crucial role in improving breeding efficiency and reducing production costs.In this study,the accuracy of three sex-linked molecular markers(SyGI[Shy Girl],FrBy[Friendly Boy],and SmY1)in sex identification was evaluated in various Actinidia species.The selected marker products were subsequently cloned and sequenced in six wild Actinidia species.Ninety-six wild A.chinensis chinensis accessions and 74 A.chinensis deliciosa accessions,most of which were wild,with only one cultivated,were used for comprehensive primer validation.Thirty-three juvenile A.chinensis chinensis hybrid seedlings were used for practical application tests.The results showed that the marker SyGI accurately identified the sex of 20 samples from six Actinidia species and 96 A.chinensis chinensis accessions with 100%reliability.For Actinidia chinensis deliciosa,the identification accuracy reached 98.65%.Sequence analysis revealed that SyGI shared the highest similarity with the male-specific genomic region.Furthermore,SyGI achieved 100%accuracy in identifying the sex of 33 juvenile A.chinensis chinensis individuals.The findings confirm that the SyGI marker possesses high accuracy,strong specificity,and broad applicability,making it a valuable tool for kiwifruit breeding programs.The cloned sequences from wild Actinidia species also provide important references for future research on the mechanisms of sexual evolution and determination.展开更多
With the rapid development of Internet technology,REST APIs(Representational State Transfer Application Programming Interfaces)have become the primary communication standard in modern microservice architectures,raisin...With the rapid development of Internet technology,REST APIs(Representational State Transfer Application Programming Interfaces)have become the primary communication standard in modern microservice architectures,raising increasing concerns about their security.Existing fuzz testing methods include random or dictionary-based input generation,which often fail to ensure both syntactic and semantic correctness,and OpenAPIbased approaches,which offer better accuracy but typically lack detailed descriptions of endpoints,parameters,or data formats.To address these issues,this paper proposes the APIDocX fuzz testing framework.It introduces a crawler tailored for dynamic web pages that automatically simulates user interactions to trigger APIs,capturing and extracting parameter information from communication packets.A multi-endpoint parameter adaptation method based on improved Jaccard similarity is then used to generalize these parameters to other potential API endpoints,filling in gaps in OpenAPI specifications.Experimental results demonstrate that the extracted parameters can be generalized with 79.61%accuracy.Fuzz testing using the enriched OpenAPI documents leads to improvements in test coverage,the number of valid test cases generated,and fault detection capabilities.This approach offers an effective enhancement to automated REST API security testing.展开更多
Graphitic carbon nitride(g-CN)stands out as the most promising candidate for solar energy conversion owing to its easy preparation,metal-free nature,flexible molecular structure,moderate bandgap,and excellent thermal/...Graphitic carbon nitride(g-CN)stands out as the most promising candidate for solar energy conversion owing to its easy preparation,metal-free nature,flexible molecular structure,moderate bandgap,and excellent thermal/chemical stability.To enhance the performance of intrinsic g-CN,a supramolecular self-assembly strategy has been proposed to regulate the molecular structure of supramolecular precursors through non-covalent interactions across molecular building blocks,thereby optimizing the electronic structure of g-CN.This review provides a comprehensive overview of the recent progress in supramolecular self-assembly-derived graphitic carbon nitride(SM-CN)from both experimental and theoretical computational research in synthesis strategies,including synthesis methods and influencing factors,providing a theoretical foundation for the design of supramolecular assembly.It also discusses modification strategies,such as internal modification of the conjugated plane,interlayer optimization,and construction of heterointerfaces to improve the electronic structure of SM-CN owing to its unique layered structure.This review further summarizes the applications of SM-CN in environment and energy,including wastewater treatment,sterilization and disinfection/air purification,water splitting,H_(2)O_(2)production,organic synthesis/biomass conversion,CO_(2)reduction,photocatalytic coupling technology.Finally,perspectives and outlooks for the future development of SM-CN aim to inspire further innovation in the design and construction of high-performance SM-CN for broader applications.展开更多
The method for malware detection based on Application Programming Interface(API)call sequences,as a primary research focus within dynamic detection technologies,currently lacks attention to subsequences of API calls,t...The method for malware detection based on Application Programming Interface(API)call sequences,as a primary research focus within dynamic detection technologies,currently lacks attention to subsequences of API calls,the variety of API call types,and the length of sequences.This oversight leads to overly complex call sequences.To address this issue,a dynamic malware detection approach based on multiple subsequences is proposed.Initially,APIs are remapped and encoded,with the introduction of percentile lengths to process sequences.Subsequently,a combination of One-Dimensional Convolutional Neural Network(1D-CNN)and Bidirectional Long Short-Term Memory(Bi-LSTM)networks,along with an attention mechanism,is employed to extract features from subsequences of varying lengths for feature fusion and classification.Experiments conducted on two widely used public API-based datasets,namelyMalBehavD-V1 and Alibaba Cloud,demonstrate that the proposedmethod reduces the number of API call types by approximately 20%compared to representative deep learning–based API sequence detection methods,while achieving a peak accuracy of 98.70%.Additionally,experimental results indicate that sequence length at the 95th percentile represents the optimal solution that balances classification performance and computational efficiency.展开更多
文摘伴随RESTful API在现代Web服务中的普及,安全问题日益凸显。而现有的主流API识别与漏洞检测工具依赖API文档或公开路径进行扫描,在识别隐藏API或无文档API时效果有限,在复杂或动态API环境下漏洞误报率高。针对这些挑战,基于上下文协议(MCP)无缝通信智能体,提出一种隐藏API发现和漏洞检测的智能体系统A2A(Agent to API vulnerability detection)来实现从API发现到漏洞检测的全流程自动化。A2A通过自适应枚举和HTTP响应分析自动识别潜在的隐藏API端点,并结合服务特定的API指纹库进行隐藏API的确认和发现。A2A在API漏洞检测上则是结合大语言模型(LLM)与检索增强生成(RAG)技术,并通过反馈迭代优化策略,自动生成高质量测试用例以验证漏洞是否存在。实验评估结果表明,A2A的平均API发现率为91.9%,假发现率为7.8%,并成功发现NAUTILUS和RESTler未能检测到的多个隐藏API漏洞。
文摘Capillary electrophoresis(CE),recognized for its minimal reagent dosage,rapid analysis,and high efficiency,holds significant promise for the analysis of traditional Chinese medicines(TCM).This article reviews the application of CE in the determination of active ingredients in TCM.The active substances of herbal medicines have been classified and discussed based on their chemical properties,and the CE methods applied to different substances are summarized and discussed.This article also provides some suggestions for future research and improvement.
基金General Project,Scientific Research Project Plan for Traditional Chinese Medicine in Hebei Province(Project No.:T2025117)。
文摘Objective:To explore the application of external application of Traditional Chinese Medicine(TCM)hot compress package combined with Kinesio Taping in postoperative nursing of total knee arthroplasty.Methods:90 patients with severe knee osteoarthritis who underwent total knee arthroplasty in our department from January to December 2022 were randomly divided into two groups using a random number table method:one group was named the conventional group(n=45),which received the standard orthopedic nursing process throughout,including basic pain management,incision care,and functional exercise guidance;the other group was defined as the experimental group(n=45),which,in addition to the conventional nursing framework,incorporated the local transdermal drug delivery technique of TCM hot compress package and the biomechanical correction scheme of Kinesio Taping for collaborative intervention.Finally,the differences in postoperative resting/active pain scores(VAS)of the affected limb and satisfaction with nursing services between the two groups were compared using quantitative assessment tools.Results:The satisfaction with nursing care in the conventional group was significantly lower than that in the experimental group(P<0.05);the VAS score after nursing in the conventional group was significantly higher than that in the experimental group(P<0.05).Conclusion:The application of external application of TCM hot compress package combined with Kinesio Taping in postoperative nursing of total knee arthroplasty has a definite effect,reducing pain and improving patient satisfaction with nursing services.
文摘Whole Slide Imaging (WSI) technology, as a revolutionary digital technology in the field of pathology, is gradually changing the traditional clinical pathological diagnosis model. By converting traditional glass pathological sections into complete digital images through high-resolution scanning, it provides a new method for pathological diagnosis. Based on this, this paper studies the application of WSI technology in clinical pathological diagnosis, elaborates on its application value, analyzes the current application status, and proposes corresponding application countermeasures, aiming to provide reference for the standardized and popularized development of this technology in clinical pathological diagnosis.
基金supported by the National Natural Science Foundation of China(Grant No.32160172)the Key Science-Technology Project of Inner Mongolia(2023KYPT0010)+1 种基金the Natural Science Foundation of Inner Mongolia Autonomous Region of China(Grant No.2025QN03006)the 2023 Inner Mongolia Public Institution High-Level Talent Introduction Scientific Research Support Project.
文摘Environmental DNA(eDNA)technology has revolutionized biodiversity monitoring with its non-invasive,sensitive,and cost-efficient approach.This paper systematically reviews eDNA advancements,examining its applications in aquatic and terrestrial ecosystems and assessing China’s standardization progress.It delineates four developmental phases from single-species detection to high-throughput sequencing,and highlights China’s contribution to the development of technical standards.While significant progress has been made,challenges persist in quantitative accuracy,methodological consistency,and large-scale implementation.Future efforts should prioritize enhanced standardization,improved quantification techniques,broader applications,and international collaboration to drive innovation in eDNA technology.
基金supported by the National Natural Science Foundation of China(21706052,22278114)Natural Science Foundation of Henan Province(242300421575).
文摘Lignin,the most abundant natural aromatic polymer globally,has garnered considerable interest due to its rich and diverse active functional groups and its antioxidant,antimicrobial,and adhesive properties.Recent research has significantly improved the performance of lignin-based hydrogels,suggesting their substantial potential in fields such as biomedicine,environmental science,and agriculture.This paper reviews the process of lignin extraction,systematically introduces synthesis strategies for preparing lignin-based hydrogels,and discusses the current state of research on these hydrogels in biomedical and environmental protection fields.It concludes by identifying the existing challenges in lignin hydrogel research and envisioning future prospects and development trends.
基金supported by National Natural Science Foundation of China(22578155,22478147)the Natural Science Foundation of Huaian City(HAB2024051).
文摘Biomass is a resourcewhose organic carbon is formed from atmospheric carbon dioxide.It has numerous characteristics such as low carbon emissions,renewability,and environmental friendliness.The efficient utilization of biomass plays a significant role in promoting the development of clean energy,alleviating environmental pressures,and achieving carbon neutrality goals.Among the numerous processing technologies of biomass,hydrothermal carbonization(HTC)is a promising thermochemical process that can decompose and convert biomass into hydrochar under relatively mild conditions of approximately 180℃–300℃,thereby enabling its efficient resource utilization.In addition,HTC can directly process feedstocks with high moisture content without the need for high-temperature drying,resulting in lower energy consumption.Based on a systematic analysis of the critical articles mainly published in 2011-2025 related to biomass,HTC,and hydrochar applications,in this review,the category of biomass was first classified and the chemical compositions were summarized.Then,the main chemical reaction pathways involved in biomass decomposition and transformation during the HTC process were introduced.Meanwhile,the roles of key process parameters,including reaction temperature,residence time,pH,feedstock type,pressure,mass ratio of biomass to water,and the use of catalysts on HTC,were carefully discussed.Finally,the applications of hydrochar in energy utilization,environmental remediation,soil improvement,adsorbent,microbial fermentation,and phosphorus recovery fields were highlighted.The future directions of the HTC process were also provided,which would respond to climate change by promoting the development of the sustainable carbon materials field.
基金funded by Sichuan Science and Technology Program,grant numbers 2021YFYZ0010,2023YFH0006,2025YFHZ0295The Basic Research Program of Sichuan Provincial Research Institutes,grant numbers 2024JDKY0001 and 2023JDKY0001.
文摘The genus Actinidia is primarily functionally dioecious,and early sex identification plays a crucial role in improving breeding efficiency and reducing production costs.In this study,the accuracy of three sex-linked molecular markers(SyGI[Shy Girl],FrBy[Friendly Boy],and SmY1)in sex identification was evaluated in various Actinidia species.The selected marker products were subsequently cloned and sequenced in six wild Actinidia species.Ninety-six wild A.chinensis chinensis accessions and 74 A.chinensis deliciosa accessions,most of which were wild,with only one cultivated,were used for comprehensive primer validation.Thirty-three juvenile A.chinensis chinensis hybrid seedlings were used for practical application tests.The results showed that the marker SyGI accurately identified the sex of 20 samples from six Actinidia species and 96 A.chinensis chinensis accessions with 100%reliability.For Actinidia chinensis deliciosa,the identification accuracy reached 98.65%.Sequence analysis revealed that SyGI shared the highest similarity with the male-specific genomic region.Furthermore,SyGI achieved 100%accuracy in identifying the sex of 33 juvenile A.chinensis chinensis individuals.The findings confirm that the SyGI marker possesses high accuracy,strong specificity,and broad applicability,making it a valuable tool for kiwifruit breeding programs.The cloned sequences from wild Actinidia species also provide important references for future research on the mechanisms of sexual evolution and determination.
基金supported by the Open Foundation of Key Laboratory of Cyberspace Security,Ministry of Education of China(KLCS20240211)。
文摘With the rapid development of Internet technology,REST APIs(Representational State Transfer Application Programming Interfaces)have become the primary communication standard in modern microservice architectures,raising increasing concerns about their security.Existing fuzz testing methods include random or dictionary-based input generation,which often fail to ensure both syntactic and semantic correctness,and OpenAPIbased approaches,which offer better accuracy but typically lack detailed descriptions of endpoints,parameters,or data formats.To address these issues,this paper proposes the APIDocX fuzz testing framework.It introduces a crawler tailored for dynamic web pages that automatically simulates user interactions to trigger APIs,capturing and extracting parameter information from communication packets.A multi-endpoint parameter adaptation method based on improved Jaccard similarity is then used to generalize these parameters to other potential API endpoints,filling in gaps in OpenAPI specifications.Experimental results demonstrate that the extracted parameters can be generalized with 79.61%accuracy.Fuzz testing using the enriched OpenAPI documents leads to improvements in test coverage,the number of valid test cases generated,and fault detection capabilities.This approach offers an effective enhancement to automated REST API security testing.
基金supported by the National Natural Science Foundation of China(NSFC No.52271228)the Natural Science Foundation of Shaanxi Province(No.2023-JC-ZD-21)the Doctoral Dissertation Innovation Fund of Xi'an University of Technology(No.101-252072301)。
文摘Graphitic carbon nitride(g-CN)stands out as the most promising candidate for solar energy conversion owing to its easy preparation,metal-free nature,flexible molecular structure,moderate bandgap,and excellent thermal/chemical stability.To enhance the performance of intrinsic g-CN,a supramolecular self-assembly strategy has been proposed to regulate the molecular structure of supramolecular precursors through non-covalent interactions across molecular building blocks,thereby optimizing the electronic structure of g-CN.This review provides a comprehensive overview of the recent progress in supramolecular self-assembly-derived graphitic carbon nitride(SM-CN)from both experimental and theoretical computational research in synthesis strategies,including synthesis methods and influencing factors,providing a theoretical foundation for the design of supramolecular assembly.It also discusses modification strategies,such as internal modification of the conjugated plane,interlayer optimization,and construction of heterointerfaces to improve the electronic structure of SM-CN owing to its unique layered structure.This review further summarizes the applications of SM-CN in environment and energy,including wastewater treatment,sterilization and disinfection/air purification,water splitting,H_(2)O_(2)production,organic synthesis/biomass conversion,CO_(2)reduction,photocatalytic coupling technology.Finally,perspectives and outlooks for the future development of SM-CN aim to inspire further innovation in the design and construction of high-performance SM-CN for broader applications.
基金supported by the National Natural Science Foundation of China(62262020)the Graduate Education Innovation Project of Hubei Minzu University(MYK2024025).
文摘The method for malware detection based on Application Programming Interface(API)call sequences,as a primary research focus within dynamic detection technologies,currently lacks attention to subsequences of API calls,the variety of API call types,and the length of sequences.This oversight leads to overly complex call sequences.To address this issue,a dynamic malware detection approach based on multiple subsequences is proposed.Initially,APIs are remapped and encoded,with the introduction of percentile lengths to process sequences.Subsequently,a combination of One-Dimensional Convolutional Neural Network(1D-CNN)and Bidirectional Long Short-Term Memory(Bi-LSTM)networks,along with an attention mechanism,is employed to extract features from subsequences of varying lengths for feature fusion and classification.Experiments conducted on two widely used public API-based datasets,namelyMalBehavD-V1 and Alibaba Cloud,demonstrate that the proposedmethod reduces the number of API call types by approximately 20%compared to representative deep learning–based API sequence detection methods,while achieving a peak accuracy of 98.70%.Additionally,experimental results indicate that sequence length at the 95th percentile represents the optimal solution that balances classification performance and computational efficiency.
