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A Situational Awareness-Based Framework for Wireless Network Management:Innovations and Applications
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作者 Gao Peng Zhang Dongchen +3 位作者 Jiang Tao Li Xingzheng Tan Youheng Liu Guanghua 《China Communications》 2025年第7期95-108,共14页
Wireless networks support numerous terminals,manage large data volumes,and provide diverse services,but the vulnerability to environmental changes leads to increased complexity and costs.Situational awareness has been... Wireless networks support numerous terminals,manage large data volumes,and provide diverse services,but the vulnerability to environmental changes leads to increased complexity and costs.Situational awareness has been widely applied in network management,but existing methods fail to find optimal solutions due to the high heterogeneity of base stations,numerous metrics,and complex intercell dependencies.To address this gap,this paper proposes a specialized framework for wireless networks,integrating an evaluation model and control approach.The framework expands the indicator set into four key areas,introduces an evaluation method,and proposes the indicator perturbation greedy(IPG)algorithm and the adjustment scheme selection method based on damping coefficient(DCSS)for effective network optimization.A case study in an urban area demonstrates the framework’s ability to balance and improve network performance,enhancing situational awareness and operational efficiency under dynamic conditions. 展开更多
关键词 communication system control system situation awareness wireless communication system wireless network optimization
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Dynamic Multi-Target Jamming Channel Allocation and Power Decision-Making in Wireless Communication Networks:A Multi-Agent Deep Reinforcement Learning Approach
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作者 Peng Xiang Xu Hua +4 位作者 Qi Zisen Wang Dan Zhang Yue Rao Ning Gu Wanyi 《China Communications》 2025年第5期71-91,共21页
This paper studies the problem of jamming decision-making for dynamic multiple communication links in wireless communication networks(WCNs).We propose a novel jamming channel allocation and power decision-making(JCAPD... This paper studies the problem of jamming decision-making for dynamic multiple communication links in wireless communication networks(WCNs).We propose a novel jamming channel allocation and power decision-making(JCAPD)approach based on multi-agent deep reinforcement learning(MADRL).In high-dynamic and multi-target aviation communication environments,the rapid changes in channels make it difficult for sensors to accurately capture instantaneous channel state information.This poses a challenge to make centralized jamming decisions with single-agent deep reinforcement learning(DRL)approaches.In response,we design a distributed multi-agent decision architecture(DMADA).We formulate multi-jammer resource allocation as a multiagent Markov decision process(MDP)and propose a fingerprint-based double deep Q-Network(FBDDQN)algorithm for solving it.Each jammer functions as an agent that interacts with the environment in this framework.Through the design of a reasonable reward and training mechanism,our approach enables jammers to achieve distributed cooperation,significantly improving the jamming success rate while considering jamming power cost,and reducing the transmission rate of links.Our experimental results show the FBDDQN algorithm is superior to the baseline methods. 展开更多
关键词 jamming resource allocation JCapD MADRL wireless communication countermeasure wireless communication networks
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Application of Bagging Ensemble Model for Fault Detection in Wireless Sensor Networks
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作者 Rahul Prasad Baghel R K 《Journal of Harbin Institute of Technology(New Series)》 2025年第5期74-85,共12页
A Wireless Sensor Network(WSN)comprises a series of spatially distributed autonomous devices,each equipped with sophisticated sensors.These sensors play a crucial role in monitoring diverse environmental conditions su... A Wireless Sensor Network(WSN)comprises a series of spatially distributed autonomous devices,each equipped with sophisticated sensors.These sensors play a crucial role in monitoring diverse environmental conditions such as light intensity,air pressure,temperature,humidity,wind,etc.These sensors are generally deployed in harsh and hostile conditions;hence they suffer from different kinds of faults.However,identifying faults in WSN data remains a complex task,as existing fault detection methods,including centralized,distributed,and hybrid approaches,rely on the spatio⁃temporal correlation among sensor nodes.Moreover,existing techniques predominantly leverage classification⁃based machine learning methods to discern the fault state within WSN.In this paper,we propose a regression⁃based bagging method to detect the faults in the network.The proposed bagging method is consisted of GRU(Gated Recurrent Unit)and Prophet model.Bagging allows weak learners to combine efforts to outperform a strong learner,hence it is appropriate to use in WSN.The proposed bagging method was first trained at the base station,then they were deployed at each SN(Sensor Node).Most of the common faults in WSN,such as transient,intermittent and permanent faults,were considered.The validity of the proposed scheme was tested using a trusted online published dataset.Using experimental studies,compared to the latest state⁃of⁃the⁃art machine learning models,the effectiveness of the proposed model is shown for fault detection.Performance evaluation in terms of false positive rate,accuracy,and false alarm rate shows the efficiency of the proposed algorithm. 展开更多
关键词 fault detection GRU PROPHET deep learning wireless sensor networks
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Multi-Scale Feature Fusion Network Model for Wireless Capsule Endoscopic Intestinal Lesion Detection
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作者 Shiren Ye Qi Meng +1 位作者 Shuo Zhang Hui Wang 《Computers, Materials & Continua》 2025年第2期2415-2429,共15页
WCE (Wireless Capsule Endoscopy) is a new technology that combines computer vision and medicine, allowing doctors to visualize the conditions inside the intestines, achieving good diagnostic results. However, due to t... WCE (Wireless Capsule Endoscopy) is a new technology that combines computer vision and medicine, allowing doctors to visualize the conditions inside the intestines, achieving good diagnostic results. However, due to the complex intestinal environment and limited pixel resolution of WCE videos, lesions are not easily detectable, and it takes an experienced doctor 1–2 h to analyze a complete WCE video. The use of computer-aided diagnostic methods, assisting or even replacing manual WCE diagnosis, has significant application value. In response to the issue of intestinal lesion detection in WCE videos, this paper proposes a multi-scale feature fusion network model TSD-YOLO based on the YOLO (You Only Look Once) architecture: (I) a Tiny Detection Layer to avoid the loss of shallow feature information for tiny-scale targets;(II) integrating a simple, parameter-free attention module (SimAM) at the neck to better extract local lesion features and fuse features;(III) incorporating a new loss function DIoU (Distance Intersection over Union) to better achieve boundary box regression for target detection. This model was validated using the WCE dataset from Kyushu University Hospital. For the dataset containing 18,000 images, the evaluation metrics of our model for 12 types of lesions, outperformed existing reported results from advanced models on this dataset, and the mAP (mean Average Precision) and precision evaluation metrics improved by 3.7% and 0.9% over the benchmark model. 展开更多
关键词 Deep learning wireless capsule endoscopy intestinal lesions YOLO
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Channel Knowledge Maps for 6G Wireless Networks:Construction,Applications,and Future Challenges
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作者 LIU Xingchen SUN Shu +2 位作者 TAO Meixia Aryan KAUSHIK YAN Hangsong 《ZTE Communications》 2025年第2期46-59,共14页
The advent of 6G wireless networks promises unprecedented connectivity,supporting ultra-high data rates,low latency,and massive device connectivity.However,these ambitious goals introduce significant challenges,partic... The advent of 6G wireless networks promises unprecedented connectivity,supporting ultra-high data rates,low latency,and massive device connectivity.However,these ambitious goals introduce significant challenges,particularly in channel estimation due to complex and dynamic propagation environments.This paper explores the concept of channel knowledge maps(CKMs)as a solution to these challenges.CKMs enable environment-aware communications by providing location-specific channel information,reducing reliance on real-time pilot measurements.We categorize CKM construction techniques into measurement-based,model-based,and hybrid methods,and examine their key applications in integrated sensing and communication(ISAC)systems,beamforming,trajectory optimization of unmanned aerial vehicles(UAVs),base station(BS)placement,and resource allocation.Furthermore,we discuss open challenges and propose future research directions to enhance the robustness,accuracy,and scalability of CKM-based systems in the evolving 6G landscape. 展开更多
关键词 channel knowledge map channel modeling wireless communication 6G
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Advancements in Passive Wireless Sensing Systems in Monitoring Harsh Environment and Healthcare Applications
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作者 Wei Yue Yunjian Guo +9 位作者 Jong‐Chul Lee Enkhzaya Ganbold Jia-Kang Wu Yang Li Cong Wang Hyun Soo Kim Young-Kee Shin Jun-Ge Liang Eun-Seong Kim Nam-Young Kim 《Nano-Micro Letters》 2025年第5期145-192,共48页
Recent advancements in passive wireless sensor technology have significantly extended the application scope of sensing,particularly in challenging environments for monitoring industry and healthcare applications.These... Recent advancements in passive wireless sensor technology have significantly extended the application scope of sensing,particularly in challenging environments for monitoring industry and healthcare applications.These systems are equipped with battery-free operation,wireless connectivity,and are designed to be both miniaturized and lightweight.Such features enable the safe,real-time monitoring of industrial environments and support high-precision physiological measurements in confined internal body spaces and on wearable epidermal devices.Despite the exploration into diverse application environments,the development of a systematic and comprehensive research framework for system architecture remains elusive,which hampers further optimization of these systems.This review,therefore,begins with an examination of application scenarios,progresses to evaluate current system architectures,and discusses the function of each component—specifically,the passive sensor module,the wireless communication model,and the readout module—within the context of key implementations in target sensing systems.Furthermore,we present case studies that demonstrate the feasibility of proposed classified components for sensing scenarios,derived from this systematic approach.By outlining a research trajectory for the application of passive wireless systems in sensing technologies,this paper aims to establish a foundation for more advanced,user-friendly applications. 展开更多
关键词 wireless sensing Passive detection Harsh environment Biomedical monitoring Flexible sensors
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Adaptive Time Synchronization in Time Sensitive-Wireless Sensor Networks Based on Stochastic Gradient Algorithms Framework
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作者 Ramadan Abdul-Rashid Mohd Amiruddin Abd Rahman +1 位作者 Kar Tim Chan Arun Kumar Sangaiah 《Computer Modeling in Engineering & Sciences》 2025年第3期2585-2616,共32页
This study proposes a novel time-synchronization protocol inspired by stochastic gradient algorithms.The clock model of each network node in this synchronizer is configured as a generic adaptive filter where different... This study proposes a novel time-synchronization protocol inspired by stochastic gradient algorithms.The clock model of each network node in this synchronizer is configured as a generic adaptive filter where different stochastic gradient algorithms can be adopted for adaptive clock frequency adjustments.The study analyzes the pairwise synchronization behavior of the protocol and proves the generalized convergence of the synchronization error and clock frequency.A novel closed-form expression is also derived for a generalized asymptotic error variance steady state.Steady and convergence analyses are then presented for the synchronization,with frequency adaptations done using least mean square(LMS),the Newton search,the gradient descent(GraDes),the normalized LMS(N-LMS),and the Sign-Data LMS algorithms.Results obtained from real-time experiments showed a better performance of our protocols as compared to the Average Proportional-Integral Synchronization Protocol(AvgPISync)regarding the impact of quantization error on synchronization accuracy,precision,and convergence time.This generalized approach to time synchronization allows flexibility in selecting a suitable protocol for different wireless sensor network applications. 展开更多
关键词 wireless sensor network time synchronization stochastic gradient algorithm MULTI-HOP
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Sine-Polynomial Chaotic Map(SPCM):A Decent Cryptographic Solution for Image Encryption in Wireless Sensor Networks
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作者 David S.Bhatti Annas W.Malik +1 位作者 Haeung Choi Ki-Il Kim 《Computers, Materials & Continua》 2025年第10期2157-2177,共21页
Traditional chaotic maps struggle with narrow chaotic ranges and inefficiencies,limiting their use for lightweight,secure image encryption in resource-constrained Wireless Sensor Networks(WSNs).We propose the SPCM,a n... Traditional chaotic maps struggle with narrow chaotic ranges and inefficiencies,limiting their use for lightweight,secure image encryption in resource-constrained Wireless Sensor Networks(WSNs).We propose the SPCM,a novel one-dimensional discontinuous chaotic system integrating polynomial and sine functions,leveraging a piecewise function to achieve a broad chaotic range()and a high Lyapunov exponent(5.04).Validated through nine benchmarks,including standard randomness tests,Diehard tests,and Shannon entropy(3.883),SPCM demonstrates superior randomness and high sensitivity to initial conditions.Applied to image encryption,SPCM achieves 0.152582 s(39%faster than some techniques)and 433.42 KB/s throughput(134%higher than some techniques),setting new benchmarks for chaotic map-based methods in WSNs.Chaos-based permutation and exclusive or(XOR)diffusion yield near-zero correlation in encrypted images,ensuring strong resistance to Statistical Attacks(SA)and accurate recovery.SPCM also exhibits a strong avalanche effect(bit difference),making it an efficient,secure solution for WSNs in domains like healthcare and smart cities. 展开更多
关键词 Chaos theory chaotic system image encryption CRYPTOGRapHY wireless sensor networks(WSNs)
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Application Research of Wireless Sensor Networks and the Internet of Things
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作者 Changjian Lv Rui Wang Man Zhao 《Journal of Electronic Research and Application》 2025年第4期283-289,共7页
In the context of the rapid iteration of information technology,the Internet of Things(IoT)has established itself as a pivotal hub connecting the digital world and the physical world.Wireless Sensor Networks(WSNs),dee... In the context of the rapid iteration of information technology,the Internet of Things(IoT)has established itself as a pivotal hub connecting the digital world and the physical world.Wireless Sensor Networks(WSNs),deeply embedded in the perception layer architecture of the IoT,play a crucial role as“tactile nerve endings.”A vast number of micro sensor nodes are widely distributed in monitoring areas according to preset deployment strategies,continuously and accurately perceiving and collecting real-time data on environmental parameters such as temperature,humidity,light intensity,air pressure,and pollutant concentration.These data are transmitted to the IoT cloud platform through stable and reliable communication links,forming a massive and detailed basic data resource pool.By using cutting-edge big data processing algorithms,machine learning models,and artificial intelligence analysis tools,in-depth mining and intelligent analysis of these multi-source heterogeneous data are conducted to generate high-value-added decision-making bases.This precisely empowers multiple fields,including agriculture,medical and health care,smart home,environmental science,and industrial manufacturing,driving intelligent transformation and catalyzing society to move towards a new stage of high-quality development.This paper comprehensively analyzes the technical cores of the IoT and WSNs,systematically sorts out the advanced key technologies of WSNs and the evolution of their strategic significance in the IoT system,deeply explores the innovative application scenarios and practical effects of the two in specific vertical fields,and looks forward to the technological evolution trends.It provides a detailed and highly practical guiding reference for researchers,technical engineers,and industrial decision-makers. 展开更多
关键词 wireless Sensor Networks Internet of Things Key technologies application fields
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Optimization of Wireless Power Receiving Coil for Near-Infrared Capsule Robot
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作者 WANG Wei ZHOU Cheng +3 位作者 JIANG Jinlei CUI Xinyuan YAN Guozheng CUI Daxiang 《Journal of Shanghai Jiaotong university(Science)》 2025年第3期425-432,共8页
An optimizing method for designing the wireless power receiving coil(RC)is proposed in this paper to address issues such as insufficient and fluctuating power supply in the near-infrared capsule robot.An elec-tromagne... An optimizing method for designing the wireless power receiving coil(RC)is proposed in this paper to address issues such as insufficient and fluctuating power supply in the near-infrared capsule robot.An elec-tromagnetic and circuit analysis is conducted to establish the magnetic induction intensity and equivalent circuit models for the wireless power transmission system.Combining these models involves using the number of layers in each dimension as the optimization variable.Constraints are imposed based on the normalized standard deviation of the receiving-end load power and spatial dimensions.At the same time,the optimization objective aims to maximize the average power of the receiving-end load.This process leads to formulating an optimization model for the RC.Finally,three-dimensional RCs with three different sets of parameters are wound,and the receiving-end load power of these coils is experimentally tested under various drive currents.The experimental values of the receiving-end load power exhibit a consistent trend with theoretical values,with experimental values consistently lower than theoretical values.The optimized coil parameters are determined by conducting comparative exper-iments,with a theoretical value of 4.6%for the normalized standard deviation of the receiving-end load power and an average experimental value of 9.6%.The study addressed the power supply issue of near-infrared capsule robots,which is important for early diagnosing and treating gastrointestinal diseases. 展开更多
关键词 near-infrared capsule robot fuorescence imaging wireless power transmission three-dimensional receiving coil design and optimization
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A miniaturized wireless electrical impedance myography platform for the long-term adaptive muscle fatigue monitoring
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作者 Shanshan Yu Yichao Gan +3 位作者 Feifan Song Qiongzhang Wang Hao Tang Zhao Li 《Journal of Semiconductors》 2025年第10期76-87,共12页
Accurate quantification of exercise interventions and changes in muscle function is essential for personalized health management.Electrical impedance myography(EIM)technology offers an innovative,noninvasive,painless,... Accurate quantification of exercise interventions and changes in muscle function is essential for personalized health management.Electrical impedance myography(EIM)technology offers an innovative,noninvasive,painless,and easy-to-perform solution for muscle health monitoring.However,current EIM platforms face a number of limitations,including large device size,wired connections,and instability of the electrode-skin interface,which limit their applicability for monitoring mus-cle movement.In this study,a miniature wireless EIM platform with a user-friendly smartphone app is proposed and devel-oped.The miniature,wireless,multi-frequency(20 kHz-1 MHz)EIM platform is equipped with flexible microneedle array elec-trodes(MAE).The advantages of MAEs over conventional electrodes were demonstrated by physical field modeling simula-tions and skin-electrode contact impedance comparison tests.The smartphone APP was developed to wirelessly operate the EIM platform,and to transmit and process real-time muscle impedance data.To validate its effectiveness,a seven-day adaptive fatigue training study was conducted,which demonstrated that the EIM platform was able to detect muscle adaptations and serve as a reliable indicator of fatigue.This study presents an innovative approach to applying EIM technology to muscle health monitoring and exercise testing,thereby advancing the development of personalized health management and athletic performance assessment. 展开更多
关键词 electrical impedance myography flexible microneedle array electrodes miniaturized wireless platform smartphone apP muscle fatigue monitoring
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虚拟AP融合CNN模型的自适应RSSI指纹定位方法 被引量:1
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作者 吴仕勋 黄文鲜 +1 位作者 李敏 徐凯 《计算机应用与软件》 北大核心 2025年第1期72-81,共10页
基于RSSI(Received Signal Strength Indication)位置指纹的Wi-Fi室内定位现已被大量应用于各类基于位置信息的服务中。但指纹定位的精度受到RSSI信号的剧烈波动影响,难以满足高精度位置信息服务的需求。为克服该困难,提出一种结合虚拟A... 基于RSSI(Received Signal Strength Indication)位置指纹的Wi-Fi室内定位现已被大量应用于各类基于位置信息的服务中。但指纹定位的精度受到RSSI信号的剧烈波动影响,难以满足高精度位置信息服务的需求。为克服该困难,提出一种结合虚拟AP技术与高精度CNN(Convolutional Neural Network)判别模型的定位方法。该方法通过距离比定位得到虚拟AP的位置,并将该信息与RSSI融合作为数据增强CNN模型的输入,确定样本的位置。设计实验方案采集实际的用户终端RSSI数据,构建指纹定位的数据集,验证所提出的指纹定位方案的有效性。实验结果表明,在该数据集上,所提出的方法在确定区域时的准确度达到91%,并将95%的定位误差控制在2 m以内。对比现有的定位方案,所提出的方案在定位精度上有显著提升。 展开更多
关键词 接收信号强度指示 指纹定位 卷积神经网络 虚拟ap
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金刚石滚轮CAD/CAPP/CAM/PDM集成系统
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作者 张瑞 郑凯 +1 位作者 朱振伟 赵华东 《机械设计与制造》 北大核心 2025年第3期358-361,共4页
针对金刚石滚轮是一种回转体零件以及其加工制造过程中信息化集成程度低等特点,对金刚石滚轮的特征信息提取、特征加工方案决策、数控程序后置处理等关键技术进行了研究,采用了产品模型数据交换标准STEP AP 242,实现对金刚石滚轮的制造... 针对金刚石滚轮是一种回转体零件以及其加工制造过程中信息化集成程度低等特点,对金刚石滚轮的特征信息提取、特征加工方案决策、数控程序后置处理等关键技术进行了研究,采用了产品模型数据交换标准STEP AP 242,实现对金刚石滚轮的制造特征信息提取,使用STEP AP 242和PDM相结合的集成方式,将金刚石滚轮三维模型作为制造加工信息的载体,并选择SolidWorks作为CAD和CAM软件,以及选择Aras Innovator作为PDM平台,使用C#编程语言和数据库技术开发了金刚石滚轮CAD/CAPP/CAM/PDM集成系统,并进行了实例验证。 展开更多
关键词 金刚石滚轮 CAD/CapP/CAM/PDM集成系统 产品模型数据交换标准ap 242
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番茄APETALA2乙烯响应因子重鉴定及抗逆相关基因筛选
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作者 史建磊 黄少勇 +2 位作者 陈先知 宰文珊 熊自立 《福建农业学报》 北大核心 2025年第2期113-122,共10页
【目的】探明番茄APETALA2乙烯响应因子(APETALA2/ethylene-responsive factor, AP2/ERF)的组学特征及生物胁迫响应机制,促进其在番茄抗病育种中的应用。【方法】利用新版公共数据进行AP2/ERF鉴定,结合番茄自交系在青枯菌(Ralstonia sol... 【目的】探明番茄APETALA2乙烯响应因子(APETALA2/ethylene-responsive factor, AP2/ERF)的组学特征及生物胁迫响应机制,促进其在番茄抗病育种中的应用。【方法】利用新版公共数据进行AP2/ERF鉴定,结合番茄自交系在青枯菌(Ralstonia solanacearum)侵染下的转录测序数据,挖掘青枯病抗性相关AP2/ERF。【结果】173个番茄AP2/ERF转录因子家族成员被鉴定,主要成簇分布在染色体端部,50.3%的AP2/ERF具有共线性,尤其是3号和8号染色体。基于系统进化关系,AP2亚家族包含22个(12.7%)成员,主要分为2类;ERF亚家族包含93个(53.8%)成员,可进一步分为6类;DREB亚家族包含49个(28.3%)成员,可进一步分为2类;RAV亚家族仅有3个成员。71对AP2/ERF同源基因的Ka/Ks值均小于1。26.8%的AP2/ERF主要在根中表达,几种生物胁迫下,ERF_4-6和DREB_2基因转录表达水平较高,尤其是Solyc03g005500.1(ERF_6)和Solyc08g078170.1(ERF_5)。青枯菌侵染下,在抗、感材料间筛选到10个差异表达AP2/ERF(分属AP2和ERF),其中Solyc06g068570.4(AP2)为正调控基因,其他9个为负调控基因。50.9%的AP2/ERF形成193对互作关系,Solyc01g096860.3(AP2_2)与Solyc08g078190.2(ERF_5)互作可信度最大,而Solyc06g068570.4(AP2)与Solyc03g093560.1(ERF_5)正负互作在番茄青枯病响应中可能发挥重要作用。【结论】综合基因组分析和转录表达鉴定了番茄AP2/ERF转录因子,获得若干青枯病响应基因,丰富了番茄抗病育种基础理论和基因资源。 展开更多
关键词 番茄 ap2/ERF转录因子 基因组特征 生物胁迫 转录表达
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NBAS-APS模式护理对瘢痕子宫产妇剖宫产术后的镇痛效果 被引量:1
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作者 张盼盼 魏娇娇 +2 位作者 袁亚苹 崔晓花 陈丽丽 《护理实践与研究》 2025年第3期459-464,共6页
目的探讨以护士为基础,以麻醉医师为督导的疼痛管理模式(NBAS-APS)护理对瘢痕子宫产妇剖宫产术后的镇痛作用,为制定个性化疼痛管理提供参考依据。方法选择择期剖宫产的瘢痕子宫经产妇120例,按照组间基线资料可比的原则分为观察组和对照... 目的探讨以护士为基础,以麻醉医师为督导的疼痛管理模式(NBAS-APS)护理对瘢痕子宫产妇剖宫产术后的镇痛作用,为制定个性化疼痛管理提供参考依据。方法选择择期剖宫产的瘢痕子宫经产妇120例,按照组间基线资料可比的原则分为观察组和对照组,各60例。对照组给予以病房责任护士为基础的常规急性疼痛护理模式,观察组采用由麻醉护士、病区责任护士共同参与的,以麻醉医生为督导的急性疼痛服务护理模式(NBAS-APS)。对比分析术后48 h内两组产妇最强疼痛评分、NRS≥4持续时间(PNRSmas)、静息痛评分、翻身活动痛评分、PCA有效按压次数以及休息情况,比较两组产妇术后镇痛效果满意度及恶心、呕吐、头晕、皮肤瘙痒和尿潴留的发生率。结果与对照组相比,术后48 h内,观察组产妇最强疼痛评分(NRSmas)、翻身活动痛评分(ANRS)、NRS≥4持续时间(PNRSmas)、有效PCA按压次数均低于对照组,差异有统计学意义(P<0.05);观察组产妇术后因为疼痛影响休息的情况均明显减少,术后镇痛满意度均明显提高,与对照组比较,差异有统计学意义(P<0.05)。两组产妇术后静息痛评分(RNRS)、不良反应发生率比较,差异无统计学意义(P>0.05)。结论NBAS-APS模式能够减轻瘢痕子宫产妇剖宫产术后疼痛,提升镇痛质量、改善镇痛效果并提高术后镇痛满意度。 展开更多
关键词 麻醉护士 瘢痕子宫 剖宫产 术后镇痛 急性疼痛服务 NBAS-apS 满意度
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低温胁迫下不同椰子品种AP2/ERF基因表达差异分析
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作者 李静 孙熹微 +4 位作者 刘小妹 丁浩 闫恒芳 冯紫菁 杨耀东 《西南农业学报》 北大核心 2025年第5期987-998,共12页
【目的】模拟低温环境,探讨海南高种椰子和绿矮椰子幼苗在不同低温胁迫处理下的耐寒性,旨在为耐寒椰子新品种的筛选以及培育提供数据支撑,也为探究椰子低温应答机制提供相应的理论依据。【方法】分别以抗寒性较强的海南高种椰子以及低... 【目的】模拟低温环境,探讨海南高种椰子和绿矮椰子幼苗在不同低温胁迫处理下的耐寒性,旨在为耐寒椰子新品种的筛选以及培育提供数据支撑,也为探究椰子低温应答机制提供相应的理论依据。【方法】分别以抗寒性较强的海南高种椰子以及低温较敏感材料绿矮椰子的6月龄幼苗为试验材料,8℃胁迫条件下,在0 h、2 h、8 h、2 d和7 d 5个时间点取样,并对样品进行生理生化指标测定、转录组测序和实时荧光定量PCR分析,拟从基因表达和代谢物水平研究不同品种椰子叶片对低温胁迫的响应机制。【结果】在8℃低温胁迫下,海南高种椰子和绿矮椰子叶片形态发生轻微变化,进一步的生理生化分析发现,耐寒品种海南高种椰子比寒敏感品种绿矮椰子响应低温胁迫更迅速,耐寒性更强。随着低温胁迫处理时间的延长,海南高种椰子和绿矮椰子的叶片电导率上升,而丙二醛含量随胁迫处理时间的延长下降。从海南高种椰子和绿矮椰子低温胁迫不同时间下的转录组数据中鉴定到172个AP2/ERF转录因子,对其中具有显著差异(P<0.05)的36个AP2/ERF转录因子进行结构域以及蛋白质理化性质分析发现,36个AP2/ERF转录因子包括31个ERF、2个RAV、3个AP2亚家族成员。CnAP2/ERF转录因子蛋白序列长度为150~1275 aa,亚细胞定位预测结果显示多数成员定位于细胞核。对36个AP2/ERF基因家族成员表达分析表明,在低温胁迫下,其中17个AP2/ERF基因的表达量在低温胁迫2 d时达到最高,在7 d时下降,11个AP2/ERF基因的表达量在7 d时达到最高。选取6个在海南高种椰子和绿矮椰子中差异显著的AP2/ERF基因进行定量PCR验证,发现其表达趋势与转录组数据结果一致。CBF1/DREB1B基因的相对表达量随着低温胁迫时间的延长而降低,但CBF2基因的表达量随着低温胁迫时间的延长而升高,在低温胁迫2 d时达到最高。【结论】通过探索海南高种椰子和绿矮椰子中不同AP2/ERF基因家族在低温胁迫下的表达模式,为进一步明确海南高种椰子和绿矮椰子耐寒性差异提供参考。最终挑选出6个响应低温胁迫的CnAP2/ERF候选基因,为进一步探索椰子低温应答机制及培育耐寒能力更强的椰子品种提供数据支持和理论参考。 展开更多
关键词 椰子 低温胁迫 ap2/ERF CBF 差异分析
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基于改进AP聚类算法的高校大学生个人行为信息画像分析
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作者 朱丽丽 《常州信息职业技术学院学报》 2025年第4期37-42,共6页
在高校信息系统的快速发展背景下,海量学生数据的积累形成了独特的校园大数据环境,为提升高校信息管理水平提供了重要的数据基础。提出了一种基于改进AP聚类算法的大学生个人行为信息画像构建方法,旨在为高校信息管理提供更精准的分析... 在高校信息系统的快速发展背景下,海量学生数据的积累形成了独特的校园大数据环境,为提升高校信息管理水平提供了重要的数据基础。提出了一种基于改进AP聚类算法的大学生个人行为信息画像构建方法,旨在为高校信息管理提供更精准的分析工具。对学生原始行为数据进行标准化预处理,确保数据的规范性和可比性;通过引入自适应调整机制优化AP算法中的参考度参数,显著提升了聚类效果。在此基础上,利用相似度函数提取学生的行为特征,并结合学院归属、学号等基本信息,构建了全面且细致的个人行为画像。为高校信息管理提供了一种创新、高效的解决方案,具有重要的理论价值和实践意义。 展开更多
关键词 高校大学生个人行为 ap聚类算法 画像分析技术 行为信息
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血清MR-proADM、PCT联合AIS-APS评分对卒中相关性肺炎的预测价值
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作者 王刚 侯悦 +2 位作者 郑艳 张金仿 李丽 《合肥医科大学学报》 2025年第8期808-813,共6页
目的探讨血肾上腺髓质素前体中段肽(MR-proADM)、降钙素原(PCT)联合急性缺血性脑卒中相关性肺炎评分(AIS-APS评分)对卒中相关性肺炎(SAP)的预测价值。方法收集200例急性缺血性脑卒中(AIS)患者的临床资料和检测血清MR-proADM和降钙素原,... 目的探讨血肾上腺髓质素前体中段肽(MR-proADM)、降钙素原(PCT)联合急性缺血性脑卒中相关性肺炎评分(AIS-APS评分)对卒中相关性肺炎(SAP)的预测价值。方法收集200例急性缺血性脑卒中(AIS)患者的临床资料和检测血清MR-proADM和降钙素原,根据是否发生SAP分为SAP组和非SAP组,单因素分析和Logistic回归分析AIS患者发生SAP的危险因素,Spearman相关性分析SAP患者血清MR-proADM、PCT与AIS-APS评分间的关联,绘制ROC曲线分析血清MR-proADM、PCT与AIS-APS评分对AIS患者SAP发生的预测价值。结果200例AIS患者中有31例发生SAP,即AIS患者SAP发生率为15.50%(31/200)。SAP组患者年龄、入院血糖、入院时NIHSS评分、吞咽障碍、中性粒细胞百分比、AIS-APS评分、PCT和MR-proADM水平较非SAP组显著升高(P<0.05)。Logistic回归分析结果发现,年龄、入院血糖、AIS-APS评分、PCT和MR-proADM均是影响AIS患者发生SAP的危险因素(P<0.05)。Spearman相关性分析发现,血清MR-proADM、PCT与AIS-APS评分呈正相关(rs=0.304和0.281,P<0.05)。绘制ROC曲线发现,血清MR-proADM、PCT、AIS-APS评分、MR-proADM+AIS-APS评分、PCT+AIS-APS评分、三者联合预测AIS患者发生SAP的AUC分别为0.752、0.834、0.836、0.880、0.902和0.927,敏感性分别为61.30%、74.20%、93.50%、96.80%、90.30%和96.80%,特异性分别为86.40%、86.40%、65.70%、68.60%、80.50%和75.70%。结论血清MR-proADM、PCT联合AIS-APS评分在SAP患者中水平升高,在SAP的预测中具有临床价值,三者联合能提升SAP的早期识别。 展开更多
关键词 卒中相关性肺炎 急性缺血性脑卒中相关性肺炎评分 肾上腺髓质素前体中段肽 降钙素原
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雷公藤红素调节TLR4/AP-1信号通路对变应性鼻炎小鼠炎症反应的影响实验研究
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作者 曹炜 陈艳丹 徐芬 《陕西医学杂志》 2025年第8期1039-1044,共6页
目的:探讨雷公藤红素(TRI)调节Toll样受体4(TLR4)/激活蛋白-1(AP-1)信号通路对变应性鼻炎(AR)小鼠炎症反应的影响。方法:将36只小鼠随机分为对照组、AR组、AR+TRI组、AR+TRI+TLR4激活剂组,每组各9只。除对照组外,其余各组采用卵清蛋白(O... 目的:探讨雷公藤红素(TRI)调节Toll样受体4(TLR4)/激活蛋白-1(AP-1)信号通路对变应性鼻炎(AR)小鼠炎症反应的影响。方法:将36只小鼠随机分为对照组、AR组、AR+TRI组、AR+TRI+TLR4激活剂组,每组各9只。除对照组外,其余各组采用卵清蛋白(OVA)法建立AR小鼠模型。建模后,AR+TRI组和AR+TRI+TLR4激活剂组小鼠腹腔注射TRI(1 mg/kg),AR组和对照组腹腔注射等量0.9%氯化钠溶液,AR+TRI+TLR4激活剂组小鼠通过尾静脉额外注射0.4 mg/kg TLR4激活剂脂多糖(LPS)溶液,治疗持续9 d。观察各组小鼠鼻部症状;酶联免疫吸附实验(ELISA)检测小鼠血清白细胞介素(IL-4)、IL-5、IL-13和OVA特异性免疫球蛋白E(OVA-sIgE)水平;苏木素-伊红(HE)染色观察小鼠鼻黏膜组织病理学变化;过碘酸-雪夫(PAS)染色观察小鼠鼻黏膜组织杯状细胞增生情况;实时荧光定量聚合酶链反应(RT-qPCR)检测小鼠鼻黏膜组织TLR4、AP-1 mRNA表达;Western blot检测小鼠鼻黏膜组织TLR4、髓样分化因子88(MyD88)、c-Jun氨基末端激酶(c-Jun)蛋白表达。结果:与对照组比较,AR组小鼠鼻黏膜组织腺体和杯状细胞增生,炎症细胞浸润,鼻部摩擦和打喷嚏次数增多,血清IL-4、IL-5、IL-13和OVA-sIgE水平升高,鼻黏膜组织TLR4、AP-1 mRNA及TLR4、MyD88、c-Jun蛋白表达水平升高(均P<0.05)。与AR组比较,AR+TRI组小鼠鼻黏膜组织腺体和杯状细胞增生减轻,炎症细胞浸润减少,鼻部摩擦和打喷嚏次数减少,血清IL-4、IL-5、IL-13和OVA-sIgE水平降低,鼻黏膜组织TLR4、AP-1 mRNA及TLR4、MyD88、c-Jun蛋白表达水平降低(均P<0.05)。TLR4激活剂逆转了AR+TRI组小鼠上述指标变化(均P<0.05)。结论:TRI可能通过抑制TLR4/AP-1通路减轻AR小鼠炎症反应。 展开更多
关键词 变应性鼻炎 雷公藤红素 炎症反应 Toll样受体4/激活蛋白-1信号通路 小鼠
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银杏素调节MAPK/AP-1信号通路对乳腺癌细胞增殖、迁移和侵袭的影响
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作者 李菊梅 吕伟伟 +2 位作者 邓雅君 李亚松 田再杰 《中国优生与遗传杂志》 2025年第1期10-16,共7页
目的探究银杏素(GK)调节丝裂原活化蛋白激酶(MAPK)/激活蛋白-1(AP-1)信号通路对乳腺癌细胞增殖、迁移和侵袭的影响。方法用不同浓度GK处理人乳腺癌细胞(MCF-7),检测细胞活性,筛选GK浓度;将MCF-7细胞分为对照组(Control组)、GK低浓度组(G... 目的探究银杏素(GK)调节丝裂原活化蛋白激酶(MAPK)/激活蛋白-1(AP-1)信号通路对乳腺癌细胞增殖、迁移和侵袭的影响。方法用不同浓度GK处理人乳腺癌细胞(MCF-7),检测细胞活性,筛选GK浓度;将MCF-7细胞分为对照组(Control组)、GK低浓度组(GK-L组)、GK中浓度组(GK-M组)、GK高浓度组(GK-H组)、GK高浓度+AP-1激活剂ASLAN003组(GK-H+ASLAN003组);采用平板克隆法检测MCF-7细胞增殖情况;采用流式细胞仪检测MCF-7细胞凋亡情况;通过划痕愈合率来观察MCF-7细胞迁移情况;Transwell小室实验检测MCF-7细胞侵袭情况;采用Wersternblot(WB)法检测MAPK/AP-1信号通路相关蛋白表达;裸鼠移植瘤实验检测GK对乳腺癌移植瘤生长的影响。结果选择GK浓度为5.0μmol/L、10.0μmol/L、20.0μmol/L用于下一步实验。与Control组比较,GK-L组、GK-M组、GK-H组MCF-7细胞克隆数、划痕愈合率、细胞侵袭数量降低,c-Jun、c-Fos、p-ERK1/2/ERK1/2、p-JNK/JNK、p-p38/p38表达降低,细胞凋亡率升高(P<0.05);与GK-H组相比,GK-H+ASLAN003组MCF-7细胞克隆数、划痕愈合率、细胞侵袭数量上升,c-Jun、c-Fos、p-ERK1/2/ERK1/2、p-JNK/JNK、p-p38/p38表达上升,细胞凋亡率下降(P<0.05);与Control组比较,GK组小鼠移植瘤质量和体积显著减小,c-Jun、c-Fos、p-ERK1/2/ERK1/2、p-JNK/JNK、p-p38/p38表达下调(P<0.05)。结论GK可以抑制MAPK/AP-1通路抑制乳腺癌增殖、迁移和侵袭能力。 展开更多
关键词 银杏素 MapK/ap-1信号通路 乳腺癌 增殖 迁移
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