Growth in urban population,urbanisation,and economic development has increased the demand for water,especially in water-scarce regions.Therefore,sustainable approaches to water management are needed to cope with the e...Growth in urban population,urbanisation,and economic development has increased the demand for water,especially in water-scarce regions.Therefore,sustainable approaches to water management are needed to cope with the effects of the urbanisation on the water environment.This study aimed to design novel configurations of tidal-flow vertical subsurface flow constructed wetlands(VFCWs)for treating urban stormwater.A series of laboratory experiments were conducted with semi-synthetic influent stormwater to examine the effects of the design and operation variables on the performance of the VFCWs and to identify optimal design and operational strategies,as well as maintenance requirements.The results show that the VFCWs can significantly reduce pollutants in urban stormwater,and that pollutant removal was related to specific VFCW designs.Models based on the artificial neural network(ANN)method were built using inputs derived from data exploratory techniques,such as analysis of variance(ANOVA)and principal component analysis(PCA).It was found that PCA reduced the dimensionality of input variables obtained from different experimental design conditions.The results show a satisfactory generalisation for predicting nitrogen and phosphorus removal with fewer variable inputs,indicating that monitoring costs and time can be reduced.展开更多
In the present paper,the hydrodynamic performance of stepped planing craft is investigated by computational fluid dynamics(CFD)analysis.For this purpose,the hydrodynamic resistances of without step,one-step,and two-st...In the present paper,the hydrodynamic performance of stepped planing craft is investigated by computational fluid dynamics(CFD)analysis.For this purpose,the hydrodynamic resistances of without step,one-step,and two-step hulls of Cougar planing craft are evaluated under different distances of the second step and LCG from aft,weight loadings,and Froude numbers(Fr).Our CFD results are appropriately validated against our conducted experimental test in National Iranians Marine Laboratory(NIMALA),Tehran,Iran.Then,the hydrodynamic resistance of intended planing crafts under various geometrical and physical conditions is predicted using artificial neural networks(ANNs).CFD analysis shows two different trends in the growth rate of resistance to weight ratio.So that,using steps for planing craft increases the resistance to weight ratio at lower Fr and decreases it at higher Fr.Additionally,by the increase of the distance between two steps,the resistance to weight ratio is decreased and the porpoising phenomenon is delayed.Furthermore,we obtained the maximum mean square error of ANNs output in the prediction of resistance to weight ratio equal to 0.0027.Finally,the predictive equation is suggested for the resistance to weight ratio of stepped planing craft according to weights and bias of designed ANNs.展开更多
In agent-based automated negotiation research area,a key problem is how to make software agent more adaptable to represent user preferences or suggestions,so that agent can take further proposals that reflect user req...In agent-based automated negotiation research area,a key problem is how to make software agent more adaptable to represent user preferences or suggestions,so that agent can take further proposals that reflect user requirements to implement ecommerce activities like automated transactions.The difficulty lies in the uncertainty of user preferences that include uncertain description and contents,non-linear and dynamic variability.In this paper,fuzzy language was used to describe the uncertainty and combine with multiple classified artificial neural networks(ANNs) for self-adaptive learning of user preferences.The refinement learning results of various negotiation contracts' satisfaction degrees in the extent of fuzzy classification can be achieved.Compared to unclassified computation,the experimental results illustrate that the learning ability and effectiveness of agents have been improved.展开更多
The paper describes the application of SDSM （statistical downscaling model） and ANNs （artificial neural networks） models for prediction of the hydrological trend due to the climate-change. The SDSM has been calibr...The paper describes the application of SDSM （statistical downscaling model） and ANNs （artificial neural networks） models for prediction of the hydrological trend due to the climate-change. The SDSM has been calibrated and generated for the possible future scenarios of meteorological variables, which are temperature and rainfall by using GCMs （global climate models）. The GCM used is SRES A2. The downscaled meteorological variables corresponding to SDSM were then used as input to the ANNs model calibrated with observed station data to simulate the corresponding future streamflow changes in the sub-catchment of Kurau River. This study has discovered the hydrological trend over the catchment. The projected monthly streamflow has shown a decreasing trend due to the increase in the, mean of temperature for overall months, except the month of August and November.展开更多
There is a need for accurate prediction of heat and mass transfer in aerodynamically designed,non-Newtonian nanofluids across aerodynamically designed,high-flux biomedical micro-devices for thermal management and reac...There is a need for accurate prediction of heat and mass transfer in aerodynamically designed,non-Newtonian nanofluids across aerodynamically designed,high-flux biomedical micro-devices for thermal management and reactive coating processes,but existing work is not uncharacteristically remiss regarding viscoelasticity,radiative heating,viscous dissipation,and homogeneous–heterogeneous reactions within a single scheme that is calibrated.This research investigates the flow of Williamson nanofluid across a dynamically wedged surface under conditions that include viscous dissipation,thermal radiation,and homogeneous-heterogeneous reactions.The paper develops a detailed mathematical approach that utilizes boundary layers to transform partial differential equations into ordinary differential equations using similarity transformations.RK4 is the technique for gaining numerical solutions,but with the addition of ANNs,there is an improvement in prediction accuracy and computational efficiency.The study investigates the influence of wedge angle parameter,along with Weissenberg number,thermal radiation parameter and Brownian motion parameter,and Schmidt number,on velocity distribution,temperature distribution,and concentra-tion distribution.Enhanced Weissenberg numbers enhance viscoelastic responses that modify velocity patterns,but radiation parameters and thermophoresis have key impacts on thermal transfer phenomena.This research develops findings that are of enormous application in aerospace,biomedical(artificial hearts and drug delivery),and industrial cooling technology applications.New findings on non-Newtonian nanofluids under full flow systems are included in this work to enhance heat transfer methods in novel fluid-based systems.展开更多
In this study,artificial neural networks(ANNs)were implemented to determine design parameters for an impressed current cathodic protection(ICCP)prototype.An ASTM A36 steel plate was tested in 3.5%NaCl solution,seawate...In this study,artificial neural networks(ANNs)were implemented to determine design parameters for an impressed current cathodic protection(ICCP)prototype.An ASTM A36 steel plate was tested in 3.5%NaCl solution,seawater,and NS4 using electrochemical impedance spectroscopy(EIS)to monitor the evolution of the substrate surface,which affects the current required to reach the protection potential(Eprot).Experimental data were collected as training datasets and analyzed using statistical methods,including box plots and correlation matrices.Subsequently,ANNs were applied to predict the current demand at different exposure times,enabling the estimation of electrochemical parameters(limiting voltage values)that can be used to optimize a self-regulating ICCP system.The obtained electrochemical parameters were then used,through Particle Swarm Optimization(PSO),to fine-tune an ANN-based proportional-integral-derivative(PID)controller for the ICCP system.展开更多
The main purpose of this study was to develop and apply an adaptive neuro-fuzzy inference system(ANFIS)and Artificial Neural Networks(ANNs)model for predicting the drying characteristics of potato,garlic and cantaloup...The main purpose of this study was to develop and apply an adaptive neuro-fuzzy inference system(ANFIS)and Artificial Neural Networks(ANNs)model for predicting the drying characteristics of potato,garlic and cantaloupe at convective hot air dryer.Drying experiments were conducted at the air temperatures of 40,50,60 and 70C and the air speeds of 0.5,1 and l.5 m/s.Drying properties were including kinetic drying,effective moisture diffusivity(Deff)and specific energy consumption(SEC).The highest value of Deff obtained 9.76×10^-9,0.13×10^-9 and 9.97×10^-10 m^2/s for potato,garlic,and cantaloupe,respectively.The lowest value of SEC for potato,garlic,and cantaloupe were calculated 1.94105,4.52105 and 2.12105 kJ/kg,respectively.Results revealed that the ANFIS model had the high ability to predict the Deff(R^2=0.9900),SEC(R^2=0.9917),moisture ratio(R^2=0.9974)and drying rate(R^2=0.9901)during drying.So ANFIS method had the high ability to evaluate all output as compared to ANNs method.展开更多
The goal of the present work is to demonstrate the potential of Artificial Neural Network(ANN)-driven Genetic Algorithm(GA)methods for energy efficiency and economic performance optimization of energy efficiency measu...The goal of the present work is to demonstrate the potential of Artificial Neural Network(ANN)-driven Genetic Algorithm(GA)methods for energy efficiency and economic performance optimization of energy efficiency measures in a multi-family house building in Greece.The energy efficiency measures include different heating/cooling systems(such as low-temperature and high-temperature heat pumps,natural gas boilers,split units),building envelope components for floor,walls,roof and windows of variable heat transfer coefficients,the installation of solar thermal collectors and PVs.The calculations of the building loads and investment and operating and maintenance costs of the measures are based on the methodology defined in Directive 2010/31/EU,while economic assumptions are based on EN 15459-1 standard.Typically,multi-objective optimization of energy efficiency measures often requires the simulation of very large numbers of cases involving numerous possible combinations,resulting in intense computational load.The results of the study indicate that ANN-driven GA methods can be used as an alternative,valuable tool for reliably predicting the optimal measures which minimize primary energy consumption and life cycle cost of the building with greatly reduced computational requirements.Through GA methods,the computational time needed for obtaining the optimal solutions is reduced by 96.4%-96.8%.展开更多
Received:06 December 2025;Accepted:25 February 2026;Published:30 March 2026 ABSTRACT:In the last decade,the importance of sustainable construction and artificial intelligence(AI)in civil engineering has been underline...Received:06 December 2025;Accepted:25 February 2026;Published:30 March 2026 ABSTRACT:In the last decade,the importance of sustainable construction and artificial intelligence(AI)in civil engineering has been underlined in many studies.Numerous studies highlighted the superiority of AI techniques over simple and mathematical regression analyses,which suffer from relatively poor generalization and an inability to capture highly non-linear relationships among inputs and output(s)parameters.In this study,to evaluate the compressive strength of concrete with glass powder(GP)and recycled aggregates,600 concrete samples were tested in the laboratory,and their results were evaluated.For intelligent assessment of concrete compressive strength(CCS),the study utilized an improved artificial neural network(ANN)with particle swarm optimization(PSO)algorithm and imperialist competitive algorithm(ICA).For training the models,the experimentally obtained data were used.The concrete ingredients formed the inputs of the AI-based predictive models of CCS.The experimental findings reveal that the implementation of recycled coarse aggregates in concrete from a sustainable construction point of view is advantageous and can enhance the CCS by 11.43%.Apart from that,findings indicate that utilization of 10%GP can lead to a nearly 20%increase in CCS(from 44.6 to 54.1 MPa).Additionally,the experimental observations show almost 40%improvement of CCS when 5%micro silica was used in the concrete mixture.Based on the findings,the study suggests the utilization of waste glass powder to partially replace cement in concrete,which can reduce the amount of cement production.This reduction from economic,energy-saving,and environmental(reduction in greenhouse gas emissions)points of view is of interest.On the other hand,the AI results show that the PSO-based ANN model outperforms the ICA-based ANN for the utilized dataset.According to the findings,the PSO-based ANN predictive model(with a coefficient of determination value of 0.939 and root mean square value of 0.113 for testing data)is a capable tool in predicting the CCS.Hence,this study recommends the implementation of AI-based models in CCS assessment.展开更多
AIM:To investigate the clinical characteristics and treatment outcomes,including visual function and overall survival(OS)of patients with ocular adnexal diffuse large B-cell lymphoma(OA-DLBCL).METHODS:This retrospecti...AIM:To investigate the clinical characteristics and treatment outcomes,including visual function and overall survival(OS)of patients with ocular adnexal diffuse large B-cell lymphoma(OA-DLBCL).METHODS:This retrospective cohort study enrolled 29 patients diagnosed with OA-DLBCL based on histopathological biopsy between 2006 and 2023.Patients were stratified into two subgroups:primary OA-DLBCL(no prior history of lymphoma)and secondary OA-DLBCL(history of DLBCL at non-ocular adnexal sites).OS was defined as the time interval from OA-DLBCL diagnosis to death from any cause.Survival analysis was performed using the Kaplan–Meier method,and prognostic factors affecting OS were identified using multivariate Cox proportional hazards regression with a stepwise selection approach.RESULTS:The cohort included 24 patients with primary OA-DLBCL(13 males,11 females;mean age:61.36±18.29y)and 5 patients with secondary OA-DLBCL(2 males,3 females;mean age:50.94±18.17y).Among the primary OA-DLBCL subgroup,12 patients(50%)presented with advanced disease(Ann Arbor stage IIIE–IV),and 16 patients(66%)were classified as T4 disease according to the tumor-node-metastasis(TNM)staging system.The mean final visual acuity was 1.72±1.10 in the primary group and 0.90±1.18 in the secondary group.The 5-year OS rate for the entire cohort was 27.7%.Multivariate analysis identified five factors significantly associated with poor survival outcomes:epiphora[adjusted hazard ratio(aHR),36.95],atherosclerotic cardiovascular disease(aHR,10.08),human immunodeficiency virus(HIV)infection(aHR,12.47),M1 stage(aHR,6.99),and secondary OA-DLBCL(aHR,6.03;all P<0.05).The median OS was 1.68y for primary OA-DLBCL and 1.12y for secondary OA-DLBCL.CONCLUSION:A substantial proportion of patients with primary OA-DLBCL present with advanced-stage disease at diagnosis.Epiphora,atherosclerotic cardiovascular disease,HIV infection,M1 stage,and secondary OA-DLBCL are independent prognostic factors for poor survival outcomes.These findings emphasize the urgent need for optimized therapeutic strategies and early screening protocols to improve the management of OA-DLBCL,particularly in developing countries.展开更多
Discontinuity traces significantly impact the mechanical properties of rock masses,making their rapid and accurate identification crucial for stability analysis.We propose a framework using the multi-scale surface var...Discontinuity traces significantly impact the mechanical properties of rock masses,making their rapid and accurate identification crucial for stability analysis.We propose a framework using the multi-scale surface variation index(MsSVI)and transfer-learning enhanced artificial neural network(ANN)for efficient discontinuity trace extraction from rock mass point clouds.Leveraging the similarity between regular geometric bodies and engineering rock masses,we extract trace feature points without manual threshold selection.Our contributions include:(1)An adaptive radius MsSVI calculation method based on density information;(2)a universal trace feature point classification model trained using MsSVI and ANN via inductive transfer learning;and(3)a random sampling L1-medial skeleton algorithm for precise trace feature point extraction,bypassing point cloud triangulation.Experimental results show that our model achieves a 90.2%F1-score on test sets,demonstrating its accuracy and robustness.Furthermore,our method excels in trace detail extraction on two datasets,surpassing existing models and highlighting its potential for rock mass structural analysis.展开更多
基金This research was partly supported by the UK Engineering and Physical Sciences Research Council(EPSRC)Studentship and Asset International,who provided the HDPE materials used to build bespoke constructed wetlands.
文摘Growth in urban population,urbanisation,and economic development has increased the demand for water,especially in water-scarce regions.Therefore,sustainable approaches to water management are needed to cope with the effects of the urbanisation on the water environment.This study aimed to design novel configurations of tidal-flow vertical subsurface flow constructed wetlands(VFCWs)for treating urban stormwater.A series of laboratory experiments were conducted with semi-synthetic influent stormwater to examine the effects of the design and operation variables on the performance of the VFCWs and to identify optimal design and operational strategies,as well as maintenance requirements.The results show that the VFCWs can significantly reduce pollutants in urban stormwater,and that pollutant removal was related to specific VFCW designs.Models based on the artificial neural network(ANN)method were built using inputs derived from data exploratory techniques,such as analysis of variance(ANOVA)and principal component analysis(PCA).It was found that PCA reduced the dimensionality of input variables obtained from different experimental design conditions.The results show a satisfactory generalisation for predicting nitrogen and phosphorus removal with fewer variable inputs,indicating that monitoring costs and time can be reduced.
文摘In the present paper,the hydrodynamic performance of stepped planing craft is investigated by computational fluid dynamics(CFD)analysis.For this purpose,the hydrodynamic resistances of without step,one-step,and two-step hulls of Cougar planing craft are evaluated under different distances of the second step and LCG from aft,weight loadings,and Froude numbers(Fr).Our CFD results are appropriately validated against our conducted experimental test in National Iranians Marine Laboratory(NIMALA),Tehran,Iran.Then,the hydrodynamic resistance of intended planing crafts under various geometrical and physical conditions is predicted using artificial neural networks(ANNs).CFD analysis shows two different trends in the growth rate of resistance to weight ratio.So that,using steps for planing craft increases the resistance to weight ratio at lower Fr and decreases it at higher Fr.Additionally,by the increase of the distance between two steps,the resistance to weight ratio is decreased and the porpoising phenomenon is delayed.Furthermore,we obtained the maximum mean square error of ANNs output in the prediction of resistance to weight ratio equal to 0.0027.Finally,the predictive equation is suggested for the resistance to weight ratio of stepped planing craft according to weights and bias of designed ANNs.
基金National Natural Science Foundation of China (No. 70631003)
文摘In agent-based automated negotiation research area,a key problem is how to make software agent more adaptable to represent user preferences or suggestions,so that agent can take further proposals that reflect user requirements to implement ecommerce activities like automated transactions.The difficulty lies in the uncertainty of user preferences that include uncertain description and contents,non-linear and dynamic variability.In this paper,fuzzy language was used to describe the uncertainty and combine with multiple classified artificial neural networks(ANNs) for self-adaptive learning of user preferences.The refinement learning results of various negotiation contracts' satisfaction degrees in the extent of fuzzy classification can be achieved.Compared to unclassified computation,the experimental results illustrate that the learning ability and effectiveness of agents have been improved.
文摘The paper describes the application of SDSM （statistical downscaling model） and ANNs （artificial neural networks） models for prediction of the hydrological trend due to the climate-change. The SDSM has been calibrated and generated for the possible future scenarios of meteorological variables, which are temperature and rainfall by using GCMs （global climate models）. The GCM used is SRES A2. The downscaled meteorological variables corresponding to SDSM were then used as input to the ANNs model calibrated with observed station data to simulate the corresponding future streamflow changes in the sub-catchment of Kurau River. This study has discovered the hydrological trend over the catchment. The projected monthly streamflow has shown a decreasing trend due to the increase in the, mean of temperature for overall months, except the month of August and November.
基金supported by the Korea Institute of Energy Technology Evaluation and Planning(KETEP)and the Ministry of Trade,Industry&Energy(MOTIE)of the Republic of Korea(No.RS-2025-02315209).
文摘There is a need for accurate prediction of heat and mass transfer in aerodynamically designed,non-Newtonian nanofluids across aerodynamically designed,high-flux biomedical micro-devices for thermal management and reactive coating processes,but existing work is not uncharacteristically remiss regarding viscoelasticity,radiative heating,viscous dissipation,and homogeneous–heterogeneous reactions within a single scheme that is calibrated.This research investigates the flow of Williamson nanofluid across a dynamically wedged surface under conditions that include viscous dissipation,thermal radiation,and homogeneous-heterogeneous reactions.The paper develops a detailed mathematical approach that utilizes boundary layers to transform partial differential equations into ordinary differential equations using similarity transformations.RK4 is the technique for gaining numerical solutions,but with the addition of ANNs,there is an improvement in prediction accuracy and computational efficiency.The study investigates the influence of wedge angle parameter,along with Weissenberg number,thermal radiation parameter and Brownian motion parameter,and Schmidt number,on velocity distribution,temperature distribution,and concentra-tion distribution.Enhanced Weissenberg numbers enhance viscoelastic responses that modify velocity patterns,but radiation parameters and thermophoresis have key impacts on thermal transfer phenomena.This research develops findings that are of enormous application in aerospace,biomedical(artificial hearts and drug delivery),and industrial cooling technology applications.New findings on non-Newtonian nanofluids under full flow systems are included in this work to enhance heat transfer methods in novel fluid-based systems.
文摘In this study,artificial neural networks(ANNs)were implemented to determine design parameters for an impressed current cathodic protection(ICCP)prototype.An ASTM A36 steel plate was tested in 3.5%NaCl solution,seawater,and NS4 using electrochemical impedance spectroscopy(EIS)to monitor the evolution of the substrate surface,which affects the current required to reach the protection potential(Eprot).Experimental data were collected as training datasets and analyzed using statistical methods,including box plots and correlation matrices.Subsequently,ANNs were applied to predict the current demand at different exposure times,enabling the estimation of electrochemical parameters(limiting voltage values)that can be used to optimize a self-regulating ICCP system.The obtained electrochemical parameters were then used,through Particle Swarm Optimization(PSO),to fine-tune an ANN-based proportional-integral-derivative(PID)controller for the ICCP system.
文摘The main purpose of this study was to develop and apply an adaptive neuro-fuzzy inference system(ANFIS)and Artificial Neural Networks(ANNs)model for predicting the drying characteristics of potato,garlic and cantaloupe at convective hot air dryer.Drying experiments were conducted at the air temperatures of 40,50,60 and 70C and the air speeds of 0.5,1 and l.5 m/s.Drying properties were including kinetic drying,effective moisture diffusivity(Deff)and specific energy consumption(SEC).The highest value of Deff obtained 9.76×10^-9,0.13×10^-9 and 9.97×10^-10 m^2/s for potato,garlic,and cantaloupe,respectively.The lowest value of SEC for potato,garlic,and cantaloupe were calculated 1.94105,4.52105 and 2.12105 kJ/kg,respectively.Results revealed that the ANFIS model had the high ability to predict the Deff(R^2=0.9900),SEC(R^2=0.9917),moisture ratio(R^2=0.9974)and drying rate(R^2=0.9901)during drying.So ANFIS method had the high ability to evaluate all output as compared to ANNs method.
文摘The goal of the present work is to demonstrate the potential of Artificial Neural Network(ANN)-driven Genetic Algorithm(GA)methods for energy efficiency and economic performance optimization of energy efficiency measures in a multi-family house building in Greece.The energy efficiency measures include different heating/cooling systems(such as low-temperature and high-temperature heat pumps,natural gas boilers,split units),building envelope components for floor,walls,roof and windows of variable heat transfer coefficients,the installation of solar thermal collectors and PVs.The calculations of the building loads and investment and operating and maintenance costs of the measures are based on the methodology defined in Directive 2010/31/EU,while economic assumptions are based on EN 15459-1 standard.Typically,multi-objective optimization of energy efficiency measures often requires the simulation of very large numbers of cases involving numerous possible combinations,resulting in intense computational load.The results of the study indicate that ANN-driven GA methods can be used as an alternative,valuable tool for reliably predicting the optimal measures which minimize primary energy consumption and life cycle cost of the building with greatly reduced computational requirements.Through GA methods,the computational time needed for obtaining the optimal solutions is reduced by 96.4%-96.8%.
文摘Received:06 December 2025;Accepted:25 February 2026;Published:30 March 2026 ABSTRACT:In the last decade,the importance of sustainable construction and artificial intelligence(AI)in civil engineering has been underlined in many studies.Numerous studies highlighted the superiority of AI techniques over simple and mathematical regression analyses,which suffer from relatively poor generalization and an inability to capture highly non-linear relationships among inputs and output(s)parameters.In this study,to evaluate the compressive strength of concrete with glass powder(GP)and recycled aggregates,600 concrete samples were tested in the laboratory,and their results were evaluated.For intelligent assessment of concrete compressive strength(CCS),the study utilized an improved artificial neural network(ANN)with particle swarm optimization(PSO)algorithm and imperialist competitive algorithm(ICA).For training the models,the experimentally obtained data were used.The concrete ingredients formed the inputs of the AI-based predictive models of CCS.The experimental findings reveal that the implementation of recycled coarse aggregates in concrete from a sustainable construction point of view is advantageous and can enhance the CCS by 11.43%.Apart from that,findings indicate that utilization of 10%GP can lead to a nearly 20%increase in CCS(from 44.6 to 54.1 MPa).Additionally,the experimental observations show almost 40%improvement of CCS when 5%micro silica was used in the concrete mixture.Based on the findings,the study suggests the utilization of waste glass powder to partially replace cement in concrete,which can reduce the amount of cement production.This reduction from economic,energy-saving,and environmental(reduction in greenhouse gas emissions)points of view is of interest.On the other hand,the AI results show that the PSO-based ANN model outperforms the ICA-based ANN for the utilized dataset.According to the findings,the PSO-based ANN predictive model(with a coefficient of determination value of 0.939 and root mean square value of 0.113 for testing data)is a capable tool in predicting the CCS.Hence,this study recommends the implementation of AI-based models in CCS assessment.
基金Supported by the Faculty of Medicine,Prince of Songkla University.Wainipitapong S has received grants from the Faculty of Medicine,Prince of Songkla University。
文摘AIM:To investigate the clinical characteristics and treatment outcomes,including visual function and overall survival(OS)of patients with ocular adnexal diffuse large B-cell lymphoma(OA-DLBCL).METHODS:This retrospective cohort study enrolled 29 patients diagnosed with OA-DLBCL based on histopathological biopsy between 2006 and 2023.Patients were stratified into two subgroups:primary OA-DLBCL(no prior history of lymphoma)and secondary OA-DLBCL(history of DLBCL at non-ocular adnexal sites).OS was defined as the time interval from OA-DLBCL diagnosis to death from any cause.Survival analysis was performed using the Kaplan–Meier method,and prognostic factors affecting OS were identified using multivariate Cox proportional hazards regression with a stepwise selection approach.RESULTS:The cohort included 24 patients with primary OA-DLBCL(13 males,11 females;mean age:61.36±18.29y)and 5 patients with secondary OA-DLBCL(2 males,3 females;mean age:50.94±18.17y).Among the primary OA-DLBCL subgroup,12 patients(50%)presented with advanced disease(Ann Arbor stage IIIE–IV),and 16 patients(66%)were classified as T4 disease according to the tumor-node-metastasis(TNM)staging system.The mean final visual acuity was 1.72±1.10 in the primary group and 0.90±1.18 in the secondary group.The 5-year OS rate for the entire cohort was 27.7%.Multivariate analysis identified five factors significantly associated with poor survival outcomes:epiphora[adjusted hazard ratio(aHR),36.95],atherosclerotic cardiovascular disease(aHR,10.08),human immunodeficiency virus(HIV)infection(aHR,12.47),M1 stage(aHR,6.99),and secondary OA-DLBCL(aHR,6.03;all P<0.05).The median OS was 1.68y for primary OA-DLBCL and 1.12y for secondary OA-DLBCL.CONCLUSION:A substantial proportion of patients with primary OA-DLBCL present with advanced-stage disease at diagnosis.Epiphora,atherosclerotic cardiovascular disease,HIV infection,M1 stage,and secondary OA-DLBCL are independent prognostic factors for poor survival outcomes.These findings emphasize the urgent need for optimized therapeutic strategies and early screening protocols to improve the management of OA-DLBCL,particularly in developing countries.
基金supported by the Fundamental Research Funds for the Central Universities(Grant No.2025XJSB01)the Founda-tion of State Key Laboratory for Geomechanics and Deep Under-ground Engineering,China University of Mining&Technology,Beijing.(Grant No.SKLGDUEK 2217)the Collaborative Inno-vation Center for Prevention and Control of Mountain Geological Hazards of Zhejiang Province(PCMGH-2022-03).
文摘Discontinuity traces significantly impact the mechanical properties of rock masses,making their rapid and accurate identification crucial for stability analysis.We propose a framework using the multi-scale surface variation index(MsSVI)and transfer-learning enhanced artificial neural network(ANN)for efficient discontinuity trace extraction from rock mass point clouds.Leveraging the similarity between regular geometric bodies and engineering rock masses,we extract trace feature points without manual threshold selection.Our contributions include:(1)An adaptive radius MsSVI calculation method based on density information;(2)a universal trace feature point classification model trained using MsSVI and ANN via inductive transfer learning;and(3)a random sampling L1-medial skeleton algorithm for precise trace feature point extraction,bypassing point cloud triangulation.Experimental results show that our model achieves a 90.2%F1-score on test sets,demonstrating its accuracy and robustness.Furthermore,our method excels in trace detail extraction on two datasets,surpassing existing models and highlighting its potential for rock mass structural analysis.
