Background While China’s socioeconomic transformation has driven divergent trends in gastrointestinal cancers,comprehensive data on esophageal,gastric,and liver cancer burden remain limited.This study examines the gl...Background While China’s socioeconomic transformation has driven divergent trends in gastrointestinal cancers,comprehensive data on esophageal,gastric,and liver cancer burden remain limited.This study examines the global burden of esophageal,gastric,and liver cancers in 2022 and analyzes the trends of age-standardized incidence and mortality rate(ASRs)in China from 2000 to 2018,thereby providing evidence for the formulation of cancer control strategies.Methods The global burden of esophageal,gastric and liver cancers including the estimated number of cases and deaths and the ASRs for incidence and mortality were from GLOBALCAN 2022 dataset.Data from 22 cancer registries in China were employed for the trend analysis of the ASRs for incidence and mortality of these three cancers.The Joinpoint model was used to compute the average annual percentage change(AAPC)of the incidence and mortality of the three cancers from 2000 to 2018.Results Globally,esophageal,gastric and liver cancers accounted for 11.8%of incident cancer cases and 19.1%of cancer deaths.China bore a disproportionately high burden,representing 43.8%,37.0%,and 42.4%of global esophageal,gastric,and liver cancer cases respectively,and 42.1%,39.4%,and 41.7%of corresponding deaths.However,the ASRs for incidence and mortality for all three cancers declined significantly in China(2000–2018),with absolute case numbers decreasing for gastric and esophageal cancers during 2010–2022.Age-specific analysis revealed most pronounced declines in incidence and mortality in populations under 40 years old,with AAPCs of less than–6.0%for esophageal cancer,around–4.0%for gastric cancer,and approximately–2.0%for liver cancer.Conclusions China has achieved remarkable progress in controlling esophageal,gastric and liver cancers,yet these malignancies remain major public health challenges.Future efforts should intensify existing prevention measures while expanding screening programs,particularly for aging populations.These findings offer valuable insights for regions undergoing similar epidemiological transitions.展开更多
Background Genitourinary cancers constitute a significant portion of the global cancer burden and have emerged as a prominent cause of cancer-related mortality.However,there remains a paucity of up-to-date statistical...Background Genitourinary cancers constitute a significant portion of the global cancer burden and have emerged as a prominent cause of cancer-related mortality.However,there remains a paucity of up-to-date statistical analyses that meticulously examine the global and national shifts in the epidemiology of genitourinary cancers.Our study aimed to provide a comprehensive understanding of the global distribution and progression of genitourinary cancers through analyses of the recently updated 2021 Global Burden of Disease(GBD)database.Methods This study presented the incidence,mortality,disability-adjusted life years(DALYs),and their respective age-standardized rates for four genitourinary cancers(bladder,kidney,prostate,and testicular cancers)by sex,age,and location from 1990 to 2021.Estimates for these data were presented with their 95%uncertainty intervals(UIs).Estimated annual percentage changes(EAPCs)and Bayesian Age-Period-Cohort(BAPC)models were utilized to further quantify the temporal dynamics of age-standardized rates(ASRs)in genitourinary cancers.Countries and territories were categorized according to socio-demographic index(SDI)quintiles.Results Globally,with the exception of a sustained decline in age-standardized incidence rates(ASIRs)for bladder cancer(EAPC=−0.36%),the ASIRs for kidney,prostate,and testicular cancers demonstrated an upward trend from 1990 to 2021(EAPC=0.53%,0.20%,and 1.43%,respectively).In terms of geographical regions,High-income North America had the highest ASIRs for both bladder(13.98 per 100,000 persons[95%UI,12.96 to 14.61])and prostate(47.02 per 100,000 persons[95%UI,44.47 to 49.04])cancers.Southern Latin America recorded the highest ASIRs for kidney(13.44 per 100,000 persons[95%UI,12.27 to 14.73])and testicular(4.98 per 100,000 persons[95%UI,4.33 to 5.72])cancers.Additionally,Central Europe(1.25%[95%CI,1.12%to 1.38%]),East Asia(2.40%[95%CI,2.21%to 2.59%]),Eastern Europe(3.74%[95%CI,3.55%to 3.92%]),and the Caribbean(5.52%[95%CI,4.32%to 6.74%])exhibited the highest EAPCs for bladder,kidney,prostate,and testicular cancers,respectively.Unlike the ASIRs,age-standardized mortality rates(ASMRs)and age-standardized DALYs rates(ASDRs)showed a downward trend over time in all types of genitourinary cancers.The disease burdens of bladder,kidney,and prostate cancers were primarily distributed among older men,while testicular cancer mainly occurred in young men.Smoking remained the primary risk factor for bladder cancer.Meanwhile,high fasting plasma glucose and high body-mass index exerted increasingly significant impacts on bladder and kidney cancers,respectively,during the study period.Projections to 2050 suggest that the global burdens of genitourinary cancers are expected to decline to varying degrees.However,regional disparities in genitourinary cancer burdens are projected to persist.Conclusions Although the results demonstrate a marginal decline in ASRs caused by genitourinary cancers,they still impose a considerable global burden and result in numerous deaths.Our study obtained and analyzed the latest epidemiological data of genitourinary cancers from the GBD 2021,offering valuable information for national healthcare professionals and policymakers to optimize resource allocation,manage costs more efficiently,and develop practical healthcare policies.展开更多
This study investigates trends in extreme precipitation events(EPEs)across Antarctica from 1979 to 2023,analyzing changes in EPE frequency,intensity,and the proportion of extreme to total precipitation.Using Self-Orga...This study investigates trends in extreme precipitation events(EPEs)across Antarctica from 1979 to 2023,analyzing changes in EPE frequency,intensity,and the proportion of extreme to total precipitation.Using Self-Organizing Map(SOM)techniques,the study distinguishes the contributions from thermodynamic,dynamic,and interaction components in explaining these trends.Positive EPE occurrence trends are observed across the Bellingshausen and Weddell Seas,Dronning Maud Land,and parts of the Southern Ocean,with declines limited to Queen Mary Land.Thermodynamic factors,responsible for 96.0%of the overall trend,are driven by increased water vapor content in polar air masses.Dynamic contributions,representing 10.8%,are linked to a strengthened Amundsen Sea Low(ASL)associated with the Southern Annular Mode(SAM)and Pacific South American(PSA)trends.Interaction effects make a slightly negative contribution(-6.8%)to the overall trend.Variations in water vapor transport and vertical velocity tied to annual 500-hPa geopotential height anomalies further explain EPE trends.These findings provide insight into the atmospheric processes that influence Antarctic EPEs,with implications for understanding the climatic impact on the polar environment.展开更多
The dominant annual cycle of sea surface temperature(SST)in the tropical Pacific exhibits an antisymmetric mode,which explains 83.4%total variance,and serves as a background of El Niño-Southern Oscillation(ENSO)....The dominant annual cycle of sea surface temperature(SST)in the tropical Pacific exhibits an antisymmetric mode,which explains 83.4%total variance,and serves as a background of El Niño-Southern Oscillation(ENSO).However,there is no consensus yet on its anomalous impacts on the phase and amplitude of ENSO.Based on data during 1982-2022,results show that anomalies of the antisymmetric mode can affect the evolution of ENSO on the interannual scale via Bjerknes feedback,in which the positive(negative)phase of the antisymmetric mode can strengthen El Niño(La Niña)in boreal winter via an earlier(delayed)seasonal cycle transition and larger(smaller)annual mean.The magnitude of the SST anomalies in the equatorial eastern Pacific can reach more than±0.3◦C,regulated by the changes in the antisymmetric mode based on random sensitivity analysis.Results reveal the spatial pattern of the annual cycle associated with the seasonal phase-locking of ENSO evolution and provide new insight into the impact of the annual cycle of background SST on ENSO,which possibly carries important implications for forecasting ENSO.展开更多
Background:C4 plants have increased substantially during the past several decades in the grasslands of the Mongolian Plateau due to regional warming.Here,we explore how the patterns of abundances of C4 annuals and C4 ...Background:C4 plants have increased substantially during the past several decades in the grasslands of the Mongolian Plateau due to regional warming.Here,we explore how the patterns of abundances of C4 annuals and C4 perennials change over space and time.Methods:A total of 280 sites with C4 plants were surveyed in four types of grasslands in 9 years.The relative biomasses of C4 plants(PC4),C4 annuals(PA4),and C4 perennials(PP4)were calculated.Structural equation modeling was used to analyze the drivers of changes in PA4 and PP4.Results:At the regional scale,PA4 on average was 11%(±19%,SD)and PP4 was 13%(±19%,SD).Spatially,C4 annuals dominated the C4 communities within an east–west belt region along 44°N and tended to spread toward northern latitudes(about 0.5°)and higher altitudes in the east mountainous areas.The abundance of C4 annuals decreased,while that of C4 perennials increased.The patterns of C4 annuals and C4 perennials were mainly controlled by temperature,growing season precipitation,and dynamics between the two life forms.Conclusions:C4 annuals exhibited competitive advantages in normal and wet years,while C4 perennials had competitive advantages in dry years.Grazing as a main human disturbance increased C4 annuals,but had no significant effect on C4 perennials.展开更多
In the tropical regions represented by Hainan,there are abundant solar and thermal resources,and it is relatively suitable for the construction of photovoltaic greenhouse(PVG).However,the construction of PVG still rel...In the tropical regions represented by Hainan,there are abundant solar and thermal resources,and it is relatively suitable for the construction of photovoltaic greenhouse(PVG).However,the construction of PVG still relies mainly on experience and is incapable of quantifying the balance between the photovoltaic(PV)generation and the light requirements for agricultural production.As a result,actual PVGs are primarily PV-based,without carefully considering the needs of agricultural daylighting.To quantify the influence of the design parameters of PVGs and the layout of PV panels on the internal daylighting of serrated PVGs,and to optimize the daylighting design of the roof,this paper utilizes the Design Builder software to establish gradient models for a multi-span serrated-type PVG in tropical regions.Gradient models were established in terms of aspects,namely span,width of longitudinal/transverse daylighting strip,height,roof angle,and photovoltaic panel coverage rate(PCR).Daylighting in the greenhouse of each gradient model was simulated,and with the annual average daily light integral(A_(DLI))and distribution uniformity(DU)as evaluation indicators,the influence of various design parameters on the daylighting inside the greenhouse was quantified.The result reveals that:(1)PCR is the decisive indicator for daylighting in the PVG,and a function between PCR and the A_(DLI) is derived as A_(DLI)=-15.5 PCR+16.841;(2)Increasing the width of longitudinal daylighting strip significantly improves the A_(DLI) and enhances DU while increasing the span has a noticeable effect on improving A_(DLI) but does not significantly enhance DU;(3)Increasing the eave height without changing PCR does not enhance A_(DLI) but effectively improves DU;increasing the transverse daylighting strip and adjusting the roof angle hardly improves A_(DLI).In summary,it is recommended that the optimal span for PVGs in tropical regions be set within the range of 6.5-8.0m,and the eave height be set within the range of 2.5-3.5m.Preferably,the longitudinal daylighting strip with a width ranging from 0.5-0.8m should be installed.Based on the above relationship function,the PCR can be calculated according to the appropriate light demand for the cultivated crops.The daylighting design theory proposed in this paper can provide a theoretical basis and reference for the healthy development of the PV industry in tropical regions.展开更多
CISCE brings together partners on the global industrial chain to collaborate and enhance global competitiveness.LOCATED in South Yorkshire in north-central England,British Steel,originally founded in 1967,is the U.K....CISCE brings together partners on the global industrial chain to collaborate and enhance global competitiveness.LOCATED in South Yorkshire in north-central England,British Steel,originally founded in 1967,is the U.K.’s only manufacturer of rail.It now produces three million tons of crude steel annually and has the distinction of maintaining stable production even during the COVID-19 pandemic,with its ironmaking,steelmaking and all rolling mills in full operation.展开更多
The 2024 Geoscience Frontiers Annual Convention was held in Kuching,Malaysia,from November 18th to 22th,2024,jointly with the 2024 IAGR Annual Convention and the 21st International Conference on Gondwana to Asia.The I...The 2024 Geoscience Frontiers Annual Convention was held in Kuching,Malaysia,from November 18th to 22th,2024,jointly with the 2024 IAGR Annual Convention and the 21st International Conference on Gondwana to Asia.The IAGR Convention attracted over 150 participants from various countries,including China,India,Australia,the Republic of Korea,Japan,Malaysia,Indonesia,Thailand,Italy,Mexico,the United Kingdom,Saudi Arabia,France,and Brunei.展开更多
The annual maximum rainfall event(AMRE)refers to the maximum consecutive five-day rainfall in a year.In North China,these events account for 15%–80%of the total summer(June–August)rainfall amount and pose a great ch...The annual maximum rainfall event(AMRE)refers to the maximum consecutive five-day rainfall in a year.In North China,these events account for 15%–80%of the total summer(June–August)rainfall amount and pose a great challenge for subseasonal-to-seasonal forecasting.Based on data analyses during 1979–2023,this study shows the interannual variability of AMRE is significantly influenced by the phase and amplitude mode of the annual cycle of the East Asian summer monsoon(EASM),characterized by two orthogonal patterns of southeasterly winds at 850 h Pa over the northwestern Pacific.The EASM phase-locked AMRE shows heavy rainfall events occurring extremely early and late in Beijing and surrounding areas,corresponding to the peak southeasterly wind anomalies in June and August.The EASM amplitude-locked AMRE exhibits extreme heavy or light rainfall over southwest areas with normal phase.Therefore,AMRE has a potential predictability on the seasonal time scale due to its phase-and amplitude-locking with the slow variation of the annual cycle of the EASM.展开更多
Journal Customer services For ordering information,claims and any enquiry concerning your joumal subeription please go to contact your nearest ofice.America:Tel:(401)515-4764 Europe,Middle East,Africa and Asia Pacifie...Journal Customer services For ordering information,claims and any enquiry concerning your joumal subeription please go to contact your nearest ofice.America:Tel:(401)515-4764 Europe,Middle East,Africa and Asia Pacifie:Emil:aiar@163com;523404392@qcom;434421224@qq.com Te:+86-551-65148112 Annual subscription rate(12 issues):US$300.展开更多
Acupuncture has been widely recognized for its significant therapeutic effects in treating a variety of conditions,including pain management,cerebrovascular diseases,cancer-related symptoms,respiratory disorders,and n...Acupuncture has been widely recognized for its significant therapeutic effects in treating a variety of conditions,including pain management,cerebrovascular diseases,cancer-related symptoms,respiratory disorders,and neurological diseases.A large body of clinical research demonstrates the substantial benefits of acupuncture,such as improving post-stroke recovery,alleviating chronic pain,reducing chemotherapy-induced symptoms,and promoting perioperative recovery.Mechanistic studies have shown that acupuncture influences multiple physiological systems,particularly the nervous,immune,and endocrine systems,providing insights into how acupuncture modulates neuroinflammation,neurotransmitter release,and immune responses.The role of acupuncture in integrative medicine is increasingly significant,with growing recognition of its therapeutic efficacy in regions outside China,particularly in Europe and the Americas.Acupuncture is expected to continue to expand its application,offering effective non-pharmacological treatment options in various fields,thereby consolidating its position in modern healthcare.Ongoing research holds the promise that acupuncture will play a key role in managing chronic diseases and supporting overall health.The 2024 acupuncture annual review will provide a comprehensive summary of the latest clinical applications and mechanistic research in acupuncture,with the aim of elucidating the current landscape and guiding future directions in the field.展开更多
The ISO Annual Meeting 2025 was successfully held in Kigali,capital of the Republic of Rwanda,on October 6-10.The event included the opening and closing ceremonies,sessions with different themes,governance meetings an...The ISO Annual Meeting 2025 was successfully held in Kigali,capital of the Republic of Rwanda,on October 6-10.The event included the opening and closing ceremonies,sessions with different themes,governance meetings and social activities.It was hosted by Rwanda Standards Board(RSB),the ISO member,marking a historic first for East Africa.展开更多
Dear Editor,Antimicrobial resistance(AMR),which represents the ability of microorganisms to withstand the effects of medications that were previously effective against them,has emerged as a pressing global health conc...Dear Editor,Antimicrobial resistance(AMR),which represents the ability of microorganisms to withstand the effects of medications that were previously effective against them,has emerged as a pressing global health concern.Antimicrobial resistance is responsible for 700000 deaths annually,with projections suggesting this could rise to 10 million by 2050(United Nations Environment Programme,2023).展开更多
1 As autumn becomes winter,I eagerly anticipate December's reunion with my older brother,Don,at SilverStar Mountain Resort.Our annual“SilverStar time”has reconnected us over the past decade,filling me with excit...1 As autumn becomes winter,I eagerly anticipate December's reunion with my older brother,Don,at SilverStar Mountain Resort.Our annual“SilverStar time”has reconnected us over the past decade,filling me with excitement and reflection.展开更多
A fish lantern performance troupe parades through the village of Wangmantian in Huangshan,Anhui Province,on 10 February.This event,a 600-year-old folk tradition,is celebrated annually by locals to pray for prosperity ...A fish lantern performance troupe parades through the village of Wangmantian in Huangshan,Anhui Province,on 10 February.This event,a 600-year-old folk tradition,is celebrated annually by locals to pray for prosperity and good fortune.展开更多
1.The state of the world’s health Today’s global health landscape presents pressing challenges that demand urgent action.Nearly half of the global population lacks access to Universal Health Coverage(UHC),leaving mi...1.The state of the world’s health Today’s global health landscape presents pressing challenges that demand urgent action.Nearly half of the global population lacks access to Universal Health Coverage(UHC),leaving millions vulnerable.Each year,100 million people are driven into extreme poverty by medical expenses.Noncommunicable diseases(NCDs),such as cancer,heart disease,and diabetes,are responsible for 41 million deaths annuallyd71%of global mortality.Communicable diseases remain a significant threat,particularly in emerging economies,with only 81%of children receiving vaccinations in 2021da 5%decline from previous years.Compounded by this,humanitarian crises in 2024 are expected to impact 300 million people,and the proportion of the population aged over 60 is projected to nearly double between 2015 and 2050.Additionally,mental illness affects over 970 million people,posing significant challenges to healthcare providers,particularly nurses.展开更多
Preterm birth(PTB)is defined as delivery before 37 weeks of gestation.PTB is associated with increased cardiovascular risk,neurodevelopmental disorders,and other diseases in infancy,childhood,and adulthood[1].Globally...Preterm birth(PTB)is defined as delivery before 37 weeks of gestation.PTB is associated with increased cardiovascular risk,neurodevelopmental disorders,and other diseases in infancy,childhood,and adulthood[1].Globally,approximately 15 million PTB cases are reported annually,posing a huge burden on individual families and the community economy[2].In the context of climate warming,O_(3) pollution has continuously increased in many countries in recent years,including China;therefore,scientific communities and government agencies must strive to mitigate ozone pollution.展开更多
Farmer Luo Baozhen receives regular weather updates on her smartphone,which help her to better manage her tea farm.Once living in precarious conditions and struggling to make ends meet,Luo now earns as much as 28,000 ...Farmer Luo Baozhen receives regular weather updates on her smartphone,which help her to better manage her tea farm.Once living in precarious conditions and struggling to make ends meet,Luo now earns as much as 28,000 yuan($3,868)annually from tea plantation on her 8 mu(0.53 hectares)of land in Pu’er,Yunnan Province.The modernisation of farming and the use of high technology have become a daily reality for farmers and significantly boosted their incomes.展开更多
ANNUAL SPECIAL|CAS Research 2024 in Retrospect The year 2024 witnessed a series of important breakthroughs in fundamental research made by scientists at the Chinese Academy of Sciences(CAS).As a special presentation,B...ANNUAL SPECIAL|CAS Research 2024 in Retrospect The year 2024 witnessed a series of important breakthroughs in fundamental research made by scientists at the Chinese Academy of Sciences(CAS).As a special presentation,BCAS takes a retrospective overview on some milestone events and outstanding discoveries in the past year.展开更多
Wetlands play a number of vital roles in the ecosystem, such as serving as nutrient sinks, preventing floods, storing carbon, and filtering water. Encroachment on wetlands has led to substantial economic and environme...Wetlands play a number of vital roles in the ecosystem, such as serving as nutrient sinks, preventing floods, storing carbon, and filtering water. Encroachment on wetlands has led to substantial economic and environmental losses, including water quality degradation, loss of biodiversity and natural habitats, reduced climate mitigation as well as social and health risks. This study evaluated the effect of different land use types on nutrient stock distribution across varying soil depths in Busega wetland. The soil samples were collected in three different land uses (annually cultivated areas, perennially cultivated areas, and the undisturbed wetland area) at three different depths (0 - 10 cm, 10 - 20 cm, and 20 - 30 cm) in 2021. The soil samples were analyzed for physicochemical soil properties including soil texture and nitrogen, phosphorus, calcium, and potassium concentrations. The interaction between land use type and soil depth did not have a significant effect on nutrient distribution. However, our results showed that the main effects of land use type and soil depth influenced nutrient stock distribution across the wetland. Higher nutrient concentrations were observed under perennial cropping system than in both annual cropping system and the undisturbed wetland area. Soils under perennial cropping systems had the highest soil organic matter (1.45%), calcium (2.06 Cmol/Kg) and potassium (0.091 Cmol/Kg) levels. Higher soil organic matter (1.40%), nitrogen (0.22%), calcium (1.74 Cmol/Kg), and potassium (0.07 Cmol/Kg) were found at the mid-soil depth of 10 - 20 cm. Our results show substantial nutrient changes due to agricultural activities in the Busega wetland, suggesting further research is urgently needed to determine if these changes have adverse effects on biodiversity and water quality of the wetland and nearby water resources.展开更多
基金supported by the National Natural Science Foundation of China(grant numbers:82273721,82304220)Cooperation Fund of CHCAMS and SZCH(grant number:CFA202201003).
文摘Background While China’s socioeconomic transformation has driven divergent trends in gastrointestinal cancers,comprehensive data on esophageal,gastric,and liver cancer burden remain limited.This study examines the global burden of esophageal,gastric,and liver cancers in 2022 and analyzes the trends of age-standardized incidence and mortality rate(ASRs)in China from 2000 to 2018,thereby providing evidence for the formulation of cancer control strategies.Methods The global burden of esophageal,gastric and liver cancers including the estimated number of cases and deaths and the ASRs for incidence and mortality were from GLOBALCAN 2022 dataset.Data from 22 cancer registries in China were employed for the trend analysis of the ASRs for incidence and mortality of these three cancers.The Joinpoint model was used to compute the average annual percentage change(AAPC)of the incidence and mortality of the three cancers from 2000 to 2018.Results Globally,esophageal,gastric and liver cancers accounted for 11.8%of incident cancer cases and 19.1%of cancer deaths.China bore a disproportionately high burden,representing 43.8%,37.0%,and 42.4%of global esophageal,gastric,and liver cancer cases respectively,and 42.1%,39.4%,and 41.7%of corresponding deaths.However,the ASRs for incidence and mortality for all three cancers declined significantly in China(2000–2018),with absolute case numbers decreasing for gastric and esophageal cancers during 2010–2022.Age-specific analysis revealed most pronounced declines in incidence and mortality in populations under 40 years old,with AAPCs of less than–6.0%for esophageal cancer,around–4.0%for gastric cancer,and approximately–2.0%for liver cancer.Conclusions China has achieved remarkable progress in controlling esophageal,gastric and liver cancers,yet these malignancies remain major public health challenges.Future efforts should intensify existing prevention measures while expanding screening programs,particularly for aging populations.These findings offer valuable insights for regions undergoing similar epidemiological transitions.
基金funded by the National Natural Science Foundation of China(grant numbers:82202877 and 8237110369)the Natural Science Foundation of Guangdong Province of China(grant number:2024A1515010599)Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support(grant number:XMLX202134).
文摘Background Genitourinary cancers constitute a significant portion of the global cancer burden and have emerged as a prominent cause of cancer-related mortality.However,there remains a paucity of up-to-date statistical analyses that meticulously examine the global and national shifts in the epidemiology of genitourinary cancers.Our study aimed to provide a comprehensive understanding of the global distribution and progression of genitourinary cancers through analyses of the recently updated 2021 Global Burden of Disease(GBD)database.Methods This study presented the incidence,mortality,disability-adjusted life years(DALYs),and their respective age-standardized rates for four genitourinary cancers(bladder,kidney,prostate,and testicular cancers)by sex,age,and location from 1990 to 2021.Estimates for these data were presented with their 95%uncertainty intervals(UIs).Estimated annual percentage changes(EAPCs)and Bayesian Age-Period-Cohort(BAPC)models were utilized to further quantify the temporal dynamics of age-standardized rates(ASRs)in genitourinary cancers.Countries and territories were categorized according to socio-demographic index(SDI)quintiles.Results Globally,with the exception of a sustained decline in age-standardized incidence rates(ASIRs)for bladder cancer(EAPC=−0.36%),the ASIRs for kidney,prostate,and testicular cancers demonstrated an upward trend from 1990 to 2021(EAPC=0.53%,0.20%,and 1.43%,respectively).In terms of geographical regions,High-income North America had the highest ASIRs for both bladder(13.98 per 100,000 persons[95%UI,12.96 to 14.61])and prostate(47.02 per 100,000 persons[95%UI,44.47 to 49.04])cancers.Southern Latin America recorded the highest ASIRs for kidney(13.44 per 100,000 persons[95%UI,12.27 to 14.73])and testicular(4.98 per 100,000 persons[95%UI,4.33 to 5.72])cancers.Additionally,Central Europe(1.25%[95%CI,1.12%to 1.38%]),East Asia(2.40%[95%CI,2.21%to 2.59%]),Eastern Europe(3.74%[95%CI,3.55%to 3.92%]),and the Caribbean(5.52%[95%CI,4.32%to 6.74%])exhibited the highest EAPCs for bladder,kidney,prostate,and testicular cancers,respectively.Unlike the ASIRs,age-standardized mortality rates(ASMRs)and age-standardized DALYs rates(ASDRs)showed a downward trend over time in all types of genitourinary cancers.The disease burdens of bladder,kidney,and prostate cancers were primarily distributed among older men,while testicular cancer mainly occurred in young men.Smoking remained the primary risk factor for bladder cancer.Meanwhile,high fasting plasma glucose and high body-mass index exerted increasingly significant impacts on bladder and kidney cancers,respectively,during the study period.Projections to 2050 suggest that the global burdens of genitourinary cancers are expected to decline to varying degrees.However,regional disparities in genitourinary cancer burdens are projected to persist.Conclusions Although the results demonstrate a marginal decline in ASRs caused by genitourinary cancers,they still impose a considerable global burden and result in numerous deaths.Our study obtained and analyzed the latest epidemiological data of genitourinary cancers from the GBD 2021,offering valuable information for national healthcare professionals and policymakers to optimize resource allocation,manage costs more efficiently,and develop practical healthcare policies.
基金supported by the National Key R&D Program of China(2022YFE0106300)Norges Forskningsråd(328886).
文摘This study investigates trends in extreme precipitation events(EPEs)across Antarctica from 1979 to 2023,analyzing changes in EPE frequency,intensity,and the proportion of extreme to total precipitation.Using Self-Organizing Map(SOM)techniques,the study distinguishes the contributions from thermodynamic,dynamic,and interaction components in explaining these trends.Positive EPE occurrence trends are observed across the Bellingshausen and Weddell Seas,Dronning Maud Land,and parts of the Southern Ocean,with declines limited to Queen Mary Land.Thermodynamic factors,responsible for 96.0%of the overall trend,are driven by increased water vapor content in polar air masses.Dynamic contributions,representing 10.8%,are linked to a strengthened Amundsen Sea Low(ASL)associated with the Southern Annular Mode(SAM)and Pacific South American(PSA)trends.Interaction effects make a slightly negative contribution(-6.8%)to the overall trend.Variations in water vapor transport and vertical velocity tied to annual 500-hPa geopotential height anomalies further explain EPE trends.These findings provide insight into the atmospheric processes that influence Antarctic EPEs,with implications for understanding the climatic impact on the polar environment.
基金jointly supported by the National Natural Science Foundation of China [grant numbers U2242205 and 41830969]the S&T Development Fund of CAMS [grant number 2023KJ036]the Basic Scientific Research and Operation Foundation of CAMS [grant number 2023Z018]。
文摘The dominant annual cycle of sea surface temperature(SST)in the tropical Pacific exhibits an antisymmetric mode,which explains 83.4%total variance,and serves as a background of El Niño-Southern Oscillation(ENSO).However,there is no consensus yet on its anomalous impacts on the phase and amplitude of ENSO.Based on data during 1982-2022,results show that anomalies of the antisymmetric mode can affect the evolution of ENSO on the interannual scale via Bjerknes feedback,in which the positive(negative)phase of the antisymmetric mode can strengthen El Niño(La Niña)in boreal winter via an earlier(delayed)seasonal cycle transition and larger(smaller)annual mean.The magnitude of the SST anomalies in the equatorial eastern Pacific can reach more than±0.3◦C,regulated by the changes in the antisymmetric mode based on random sensitivity analysis.Results reveal the spatial pattern of the annual cycle associated with the seasonal phase-locking of ENSO evolution and provide new insight into the impact of the annual cycle of background SST on ENSO,which possibly carries important implications for forecasting ENSO.
基金supported by the DFG within the DFG research group 536(MAGIM)the National Natural Science Foundation of China(31630010 and 31320103916).
文摘Background:C4 plants have increased substantially during the past several decades in the grasslands of the Mongolian Plateau due to regional warming.Here,we explore how the patterns of abundances of C4 annuals and C4 perennials change over space and time.Methods:A total of 280 sites with C4 plants were surveyed in four types of grasslands in 9 years.The relative biomasses of C4 plants(PC4),C4 annuals(PA4),and C4 perennials(PP4)were calculated.Structural equation modeling was used to analyze the drivers of changes in PA4 and PP4.Results:At the regional scale,PA4 on average was 11%(±19%,SD)and PP4 was 13%(±19%,SD).Spatially,C4 annuals dominated the C4 communities within an east–west belt region along 44°N and tended to spread toward northern latitudes(about 0.5°)and higher altitudes in the east mountainous areas.The abundance of C4 annuals decreased,while that of C4 perennials increased.The patterns of C4 annuals and C4 perennials were mainly controlled by temperature,growing season precipitation,and dynamics between the two life forms.Conclusions:C4 annuals exhibited competitive advantages in normal and wet years,while C4 perennials had competitive advantages in dry years.Grazing as a main human disturbance increased C4 annuals,but had no significant effect on C4 perennials.
基金2024 Science and Technology Commissioner Service Group's Emergency Science and Technology Research Project for Wind Disaster Relief in Hainan Province(ZDYF2024YJGG002-8)China Huaneng Group Co.,Ltd.Headquarters Technology Project,Optimization of Photovoltaic Vegetable Greenhouse Structure and Research on Planting Agronomy in Tropical Regions(HNKJ22-HF77)。
文摘In the tropical regions represented by Hainan,there are abundant solar and thermal resources,and it is relatively suitable for the construction of photovoltaic greenhouse(PVG).However,the construction of PVG still relies mainly on experience and is incapable of quantifying the balance between the photovoltaic(PV)generation and the light requirements for agricultural production.As a result,actual PVGs are primarily PV-based,without carefully considering the needs of agricultural daylighting.To quantify the influence of the design parameters of PVGs and the layout of PV panels on the internal daylighting of serrated PVGs,and to optimize the daylighting design of the roof,this paper utilizes the Design Builder software to establish gradient models for a multi-span serrated-type PVG in tropical regions.Gradient models were established in terms of aspects,namely span,width of longitudinal/transverse daylighting strip,height,roof angle,and photovoltaic panel coverage rate(PCR).Daylighting in the greenhouse of each gradient model was simulated,and with the annual average daily light integral(A_(DLI))and distribution uniformity(DU)as evaluation indicators,the influence of various design parameters on the daylighting inside the greenhouse was quantified.The result reveals that:(1)PCR is the decisive indicator for daylighting in the PVG,and a function between PCR and the A_(DLI) is derived as A_(DLI)=-15.5 PCR+16.841;(2)Increasing the width of longitudinal daylighting strip significantly improves the A_(DLI) and enhances DU while increasing the span has a noticeable effect on improving A_(DLI) but does not significantly enhance DU;(3)Increasing the eave height without changing PCR does not enhance A_(DLI) but effectively improves DU;increasing the transverse daylighting strip and adjusting the roof angle hardly improves A_(DLI).In summary,it is recommended that the optimal span for PVGs in tropical regions be set within the range of 6.5-8.0m,and the eave height be set within the range of 2.5-3.5m.Preferably,the longitudinal daylighting strip with a width ranging from 0.5-0.8m should be installed.Based on the above relationship function,the PCR can be calculated according to the appropriate light demand for the cultivated crops.The daylighting design theory proposed in this paper can provide a theoretical basis and reference for the healthy development of the PV industry in tropical regions.
文摘CISCE brings together partners on the global industrial chain to collaborate and enhance global competitiveness.LOCATED in South Yorkshire in north-central England,British Steel,originally founded in 1967,is the U.K.’s only manufacturer of rail.It now produces three million tons of crude steel annually and has the distinction of maintaining stable production even during the COVID-19 pandemic,with its ironmaking,steelmaking and all rolling mills in full operation.
文摘The 2024 Geoscience Frontiers Annual Convention was held in Kuching,Malaysia,from November 18th to 22th,2024,jointly with the 2024 IAGR Annual Convention and the 21st International Conference on Gondwana to Asia.The IAGR Convention attracted over 150 participants from various countries,including China,India,Australia,the Republic of Korea,Japan,Malaysia,Indonesia,Thailand,Italy,Mexico,the United Kingdom,Saudi Arabia,France,and Brunei.
基金jointly supported by the National Natural Science Foundation of China(Grant Nos.U2242205 and 42375033)the Second Tibetan Plateau Scientific Expedition and Research(STEP)program(Grant No.2019QZKK0105)+1 种基金the Basic Scientific Research and Operation Foundation of CAMS(2023Z018)the S&T Development Fund of CAMS(Grant No.2023KJ036)。
文摘The annual maximum rainfall event(AMRE)refers to the maximum consecutive five-day rainfall in a year.In North China,these events account for 15%–80%of the total summer(June–August)rainfall amount and pose a great challenge for subseasonal-to-seasonal forecasting.Based on data analyses during 1979–2023,this study shows the interannual variability of AMRE is significantly influenced by the phase and amplitude mode of the annual cycle of the East Asian summer monsoon(EASM),characterized by two orthogonal patterns of southeasterly winds at 850 h Pa over the northwestern Pacific.The EASM phase-locked AMRE shows heavy rainfall events occurring extremely early and late in Beijing and surrounding areas,corresponding to the peak southeasterly wind anomalies in June and August.The EASM amplitude-locked AMRE exhibits extreme heavy or light rainfall over southwest areas with normal phase.Therefore,AMRE has a potential predictability on the seasonal time scale due to its phase-and amplitude-locking with the slow variation of the annual cycle of the EASM.
文摘Journal Customer services For ordering information,claims and any enquiry concerning your joumal subeription please go to contact your nearest ofice.America:Tel:(401)515-4764 Europe,Middle East,Africa and Asia Pacifie:Emil:aiar@163com;523404392@qcom;434421224@qq.com Te:+86-551-65148112 Annual subscription rate(12 issues):US$300.
基金supported by the National Key Research and Development Program of China(No.2022YFC3500601)the National Natural Science Foundation of China(Nos.82474395 and 81973755)+1 种基金the Project on Hebei Administration of Traditional Chinese Medicine(Nos.2022091 and 2025424)the Graduate Innovation Projects of Hebei University of Chinese Medicine(Nos.XCXZZBS2024005 and XCXZZBS2025029).
文摘Acupuncture has been widely recognized for its significant therapeutic effects in treating a variety of conditions,including pain management,cerebrovascular diseases,cancer-related symptoms,respiratory disorders,and neurological diseases.A large body of clinical research demonstrates the substantial benefits of acupuncture,such as improving post-stroke recovery,alleviating chronic pain,reducing chemotherapy-induced symptoms,and promoting perioperative recovery.Mechanistic studies have shown that acupuncture influences multiple physiological systems,particularly the nervous,immune,and endocrine systems,providing insights into how acupuncture modulates neuroinflammation,neurotransmitter release,and immune responses.The role of acupuncture in integrative medicine is increasingly significant,with growing recognition of its therapeutic efficacy in regions outside China,particularly in Europe and the Americas.Acupuncture is expected to continue to expand its application,offering effective non-pharmacological treatment options in various fields,thereby consolidating its position in modern healthcare.Ongoing research holds the promise that acupuncture will play a key role in managing chronic diseases and supporting overall health.The 2024 acupuncture annual review will provide a comprehensive summary of the latest clinical applications and mechanistic research in acupuncture,with the aim of elucidating the current landscape and guiding future directions in the field.
文摘The ISO Annual Meeting 2025 was successfully held in Kigali,capital of the Republic of Rwanda,on October 6-10.The event included the opening and closing ceremonies,sessions with different themes,governance meetings and social activities.It was hosted by Rwanda Standards Board(RSB),the ISO member,marking a historic first for East Africa.
基金supported by the National Council for Scientific and Technological Development(CNPq),Brazil(Nos.150712/2022-7 and 304905/2022-4)the Sao Paulo Research Foundation(FAPESP),Brazil(No.2021/01655-7)the Directorate of Research of the Universidad Técnica de Ambato,Ecuador for sponsoring the Project“Application of New Generation Sequencing Technologies—NGS—in the Analysis of Microbial Contamination in Water Bodies and Evaluation of High Priority Pathogens”。
文摘Dear Editor,Antimicrobial resistance(AMR),which represents the ability of microorganisms to withstand the effects of medications that were previously effective against them,has emerged as a pressing global health concern.Antimicrobial resistance is responsible for 700000 deaths annually,with projections suggesting this could rise to 10 million by 2050(United Nations Environment Programme,2023).
文摘1 As autumn becomes winter,I eagerly anticipate December's reunion with my older brother,Don,at SilverStar Mountain Resort.Our annual“SilverStar time”has reconnected us over the past decade,filling me with excitement and reflection.
文摘A fish lantern performance troupe parades through the village of Wangmantian in Huangshan,Anhui Province,on 10 February.This event,a 600-year-old folk tradition,is celebrated annually by locals to pray for prosperity and good fortune.
文摘1.The state of the world’s health Today’s global health landscape presents pressing challenges that demand urgent action.Nearly half of the global population lacks access to Universal Health Coverage(UHC),leaving millions vulnerable.Each year,100 million people are driven into extreme poverty by medical expenses.Noncommunicable diseases(NCDs),such as cancer,heart disease,and diabetes,are responsible for 41 million deaths annuallyd71%of global mortality.Communicable diseases remain a significant threat,particularly in emerging economies,with only 81%of children receiving vaccinations in 2021da 5%decline from previous years.Compounded by this,humanitarian crises in 2024 are expected to impact 300 million people,and the proportion of the population aged over 60 is projected to nearly double between 2015 and 2050.Additionally,mental illness affects over 970 million people,posing significant challenges to healthcare providers,particularly nurses.
基金supported by the Natural Science Foundation of Henan Province[grant number:242300420115]Key Scientific Research Projects in Universities of Henan Province[grant number:23A330006].
文摘Preterm birth(PTB)is defined as delivery before 37 weeks of gestation.PTB is associated with increased cardiovascular risk,neurodevelopmental disorders,and other diseases in infancy,childhood,and adulthood[1].Globally,approximately 15 million PTB cases are reported annually,posing a huge burden on individual families and the community economy[2].In the context of climate warming,O_(3) pollution has continuously increased in many countries in recent years,including China;therefore,scientific communities and government agencies must strive to mitigate ozone pollution.
文摘Farmer Luo Baozhen receives regular weather updates on her smartphone,which help her to better manage her tea farm.Once living in precarious conditions and struggling to make ends meet,Luo now earns as much as 28,000 yuan($3,868)annually from tea plantation on her 8 mu(0.53 hectares)of land in Pu’er,Yunnan Province.The modernisation of farming and the use of high technology have become a daily reality for farmers and significantly boosted their incomes.
文摘ANNUAL SPECIAL|CAS Research 2024 in Retrospect The year 2024 witnessed a series of important breakthroughs in fundamental research made by scientists at the Chinese Academy of Sciences(CAS).As a special presentation,BCAS takes a retrospective overview on some milestone events and outstanding discoveries in the past year.
文摘Wetlands play a number of vital roles in the ecosystem, such as serving as nutrient sinks, preventing floods, storing carbon, and filtering water. Encroachment on wetlands has led to substantial economic and environmental losses, including water quality degradation, loss of biodiversity and natural habitats, reduced climate mitigation as well as social and health risks. This study evaluated the effect of different land use types on nutrient stock distribution across varying soil depths in Busega wetland. The soil samples were collected in three different land uses (annually cultivated areas, perennially cultivated areas, and the undisturbed wetland area) at three different depths (0 - 10 cm, 10 - 20 cm, and 20 - 30 cm) in 2021. The soil samples were analyzed for physicochemical soil properties including soil texture and nitrogen, phosphorus, calcium, and potassium concentrations. The interaction between land use type and soil depth did not have a significant effect on nutrient distribution. However, our results showed that the main effects of land use type and soil depth influenced nutrient stock distribution across the wetland. Higher nutrient concentrations were observed under perennial cropping system than in both annual cropping system and the undisturbed wetland area. Soils under perennial cropping systems had the highest soil organic matter (1.45%), calcium (2.06 Cmol/Kg) and potassium (0.091 Cmol/Kg) levels. Higher soil organic matter (1.40%), nitrogen (0.22%), calcium (1.74 Cmol/Kg), and potassium (0.07 Cmol/Kg) were found at the mid-soil depth of 10 - 20 cm. Our results show substantial nutrient changes due to agricultural activities in the Busega wetland, suggesting further research is urgently needed to determine if these changes have adverse effects on biodiversity and water quality of the wetland and nearby water resources.
