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基于全基因组平均核苷酸一致性(ANI)的微生态活菌制品菌株分类及命名变化研究
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作者 冯丹阳 胡文红 +2 位作者 郭君贞 邢晟 丁勃 《药物分析杂志》 北大核心 2025年第8期1427-1441,共15页
目的:利用微生态活菌制品中菌株的全基因组序列数据,使用平均核苷酸一致性(ANI)分析,确认微生态活菌制品中菌株的种属信息,进一步明确菌株的分类和命名。方法:对上市微生态活菌制品中的菌株进行分离和纯化,获取的16个菌株进行高通量测序... 目的:利用微生态活菌制品中菌株的全基因组序列数据,使用平均核苷酸一致性(ANI)分析,确认微生态活菌制品中菌株的种属信息,进一步明确菌株的分类和命名。方法:对上市微生态活菌制品中的菌株进行分离和纯化,获取的16个菌株进行高通量测序,采用FastANI软件将菌株全基因组序列与NCBI数据库中经认证的标准菌株基因组进行比对,根据ANI分析结果明确菌株的种属信息。结果:研究结果表明,16个菌株分别属于11个种,其中有6个种与原命名不一致,涉及超过半数已上市的微生态活菌制品。结论:建议按照实际种属信息更正部分错误命名的菌株名称,并建立微生态活菌制品生产用菌株遗传信息数据库,定期对菌株进行遗传信息的确认和比对,以保障微生态活菌制品的安全和质量。 展开更多
关键词 微生态活菌制品 全基因组测序 平均核苷酸一致性(ani) 菌株分类 遗传信息数据库
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肠杆菌科菌株基因组水平上的遗传差异(ANI)及其在菌种鉴定上的应用
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作者 张雯 杜鹏程 +3 位作者 王海印 于伟文 张媛媛 陈晨 《中国医药指南》 2013年第13期67-68,共2页
本研究探讨了高通量测序方法在肠杆菌科菌种鉴定中直接应用的可能性,第一次提出并验证了基因组平均遗传相似度(ANI)指标在肠杆菌科鉴定中的有效性,为该技术的进一步发展提供了数据积累。
关键词 肠杆菌 基因组 ani 菌种鉴定
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新型镇痛监测:镇痛与伤害性刺激指数(ANI)的临床研究进展 被引量:5
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作者 时胜男 冯艺 《中国疼痛医学杂志》 CAS CSCD 北大核心 2014年第6期424-426,共3页
此文综述镇痛与伤害性刺激指数(analgesia nociception index,ANI)近年来的临床研究概况。文章认为ANI可安全有效地监测镇痛水平,同时对于手术中的伤害性刺激具有一定的探测性,其敏感性和特异性均在可接受的范围内。与传统的镇痛监测方... 此文综述镇痛与伤害性刺激指数(analgesia nociception index,ANI)近年来的临床研究概况。文章认为ANI可安全有效地监测镇痛水平,同时对于手术中的伤害性刺激具有一定的探测性,其敏感性和特异性均在可接受的范围内。与传统的镇痛监测方法相比较,ANI具有显著优势和广泛应用前景。 展开更多
关键词 镇痛 伤害性刺激 监测 ani
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The relationship between syntax and semantics in the case of Ma'ani Nahwi in Arabic and the idea of Modistae in Latin
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作者 Solehah Hi. Yaacob 《Sino-US English Teaching》 2010年第2期45-51,58,共8页
The research emphasizes on the relation of the Arabic concept of "ma'ani nahwi" and the Latin "modistae". In order to establish this relation, the researcher illustrates the role of Aristotle's categories in inf... The research emphasizes on the relation of the Arabic concept of "ma'ani nahwi" and the Latin "modistae". In order to establish this relation, the researcher illustrates the role of Aristotle's categories in influencing the concept of the Medieval Latin "modistae". This is followed by a reevaluation of the influence of Arabic philosophers, such as al-Farabi (c.870-c.950 CE), Avicenna (980-1037 CE) and Averoes (c.1126-c.1198 CE) on Latin philosophy and linguistics, especially Jurjani's (d.1078 CE) role in introducing his concept of "nazm" towards "ma'ani nahwi". The research contributes to the understanding of the relationship between syntax and semantics which has not been effectively clarified within the framework of traditional Arabic grammatical theory. 展开更多
关键词 connection Ma ani Nahw Arabic grammatical concept the style of Modistae thinking Jurjani and Averroes
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Integrative transcriptome,proteome,and microRNA analysis reveals the effects of nitrogen sufficiency and deficiency conditions on theanine metabolism in the tea plant(Camellia sinensis) 被引量:8
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作者 Zhi-Wei Liu Hui Li +2 位作者 Jie-Xia Liu Yu Wang Jing Zhuang 《Horticulture Research》 SCIE 2020年第1期1865-1877,共13页
Nitrogen(N)is associated with amino acid metabolism in higher plants.Theanine is an important amino acid in tea plants.To explore the relationship between theanine metabolism and N conditions,we examined the different... Nitrogen(N)is associated with amino acid metabolism in higher plants.Theanine is an important amino acid in tea plants.To explore the relationship between theanine metabolism and N conditions,we examined the differentially expressed genes(DEGs),proteins(DEPs),and microRNAs(DEMs)involved in theanine metabolism in tea plant shoots and roots under N sufficiency and deficiency conditions.Transcriptome,proteome,and microRNA analyses were performed on tea plant shoots and roots under N sufficiency and deficiency conditions.The contents of theanine,expression levels of genes involved in theanine metabolism,contents of proteinogenic amino acids,and activity of enzymes were analyzed.The DEP–DEG correlation pairs and negative DEM–DEG interactions related to theanine metabolism were identified based on correlation analyses.The expression profiles of DEGs and negative DEM–DEG pairs related to theanine biosynthesis were consistent with the sequencing results.Our results suggest that the molecular and physiological mechanism of theanine accumulation is significantly affected by N sufficiency and deficiency conditions.The DEGs,DEPs,and DEMs and the activity of the enzymes involved in theanine biosynthesis might play vital roles in theanine accumulation under N sufficiency and deficiency conditions in the shoots and roots of tea plants. 展开更多
关键词 METABOLISM SINENSIS ani
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ANI与船舶通信安全管理 被引量:1
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作者 刘定伟 《中国水运》 2008年第10期42-42,共1页
长江航运发展迅猛,由于种种原因,损害航行船舶安全通信秩序的行为时有发生,应用ANI能有效维护通信秩序,确保长江船舶航行安全。
关键词 ani 编码器 通信管理
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Metabolomic Profiling of Mice Exposed toα-amanitin Using Ultra-performance Liquid Chromatography Quadrupole Time-of-flight Tandem Mass Spectrometry
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作者 LI Lei ZHENG Chong +11 位作者 YE Jian Fang ZHU Kai ZHOU Yi Bing LIU Jia GAO Ming WU Yu Tian LIU Yong Ting LIU Li Ya LIN Ye LI Hai Chang ZHANG Quan GUO Hua 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2023年第3期289-294,共6页
Numerous instances of poisoning caused by the ingestion of mushrooms are reported annually worldwide,with most mushroom poisoning deaths caused by the ingestion of toxic amanita fungi.Amatoxin is the main toxic compon... Numerous instances of poisoning caused by the ingestion of mushrooms are reported annually worldwide,with most mushroom poisoning deaths caused by the ingestion of toxic amanita fungi.Amatoxin is the main toxic component of amanita,andα-amanitin is one of the most potent toxins present in amatoxin[1]. 展开更多
关键词 Metab ani annually
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The Perineal Membrane: Its Composite Fibers and Nerve Content, and Relationship to the Levator Ani and Deep Transverse Perineal Muscles
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作者 Tetsuji Kurokawa Nobuyuki Hinata +4 位作者 Hiromasa Sasaki Gen Murakami Masato Fujisawa Shin-Ichi Abe Yoshio Yosida 《Open Journal of Obstetrics and Gynecology》 2014年第7期405-415,共11页
The perineal membrane (PM) is a thick, elastic fiber-rich, smooth muscle-poor membrane extending along the vestibule and lower vaginal wall and embedding the urethrovaginal sphincter and compressor urethrae muscles. T... The perineal membrane (PM) is a thick, elastic fiber-rich, smooth muscle-poor membrane extending along the vestibule and lower vaginal wall and embedding the urethrovaginal sphincter and compressor urethrae muscles. To provide a better understanding of the topographical relationship between the PM and the levator ani muscle, we examined histological sections from 15 female cadavers. The composite fibers of the PM were usually continuous with that of a fascia covering the inferior or lateral surface of the levator ani (fascia diaphragmatis pelvis inferior) rather than the endopelvic fascia covering the superior or medial surface of the latter muscle. However, this fascial connection was sometimes interrupted by a venous plexus. The deep transverse perineal muscle was consistently adjacent to the posterolateral aspect of the PM, but whether it extended superficially or deeply to the PM depended on size of the muscle. In contrast to the endopelvic fascia embedding abundant middle-sized nerves (cavernous and sphincter nerves;0.05 - 0.1 mm in thickness), the PM contained very thin nerves: many in 10 cadavers but few in 5 cadavers. Most of the nerves seemed to be sensory on the basis of immunohistochemistry. The levator ani muscle was considered likely to provide traction force to the PM, but active elevation appeared to be difficult because of the highly elastic nature of the PM and the interrupting venous plexus. Loss of nerves in the PM might be one of a number of factors that can accelerate pelvic organ prolapse. 展开更多
关键词 VAGINA Levator ani Muscle PERINEAL MEMBRANE SMOOTH Muscles Elastic Fibers NERVES
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ANI环氧/碳纳米管复合材料取得突破进展
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《热固性树脂》 CAS CSCD 2008年第4期12-12,共1页
关键词 环氧树脂基 碳纳米管复合材料 ani 材料开发 德克萨斯 体育用品
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Composition of Trans-anethol and Other Aromatic Volatiles in Anisated Alcoholic Beverages by Head-Space GC-MS Chromatography
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作者 Marie Gerogiannaki Theophilos Masouras 《Journal of Environmental Science and Engineering(A)》 2015年第1期36-39,共4页
Aniseed distillates, like ouzo in Greece, raki in Turkey, pastis in France, and arak in Syria, are very popular in Mediterranean countries. This flavoured alcoholic beverage is produced by extraction and distillation ... Aniseed distillates, like ouzo in Greece, raki in Turkey, pastis in France, and arak in Syria, are very popular in Mediterranean countries. This flavoured alcoholic beverage is produced by extraction and distillation of fermented grape pomaces with herbal seeds from aromatic plants like Pimpinella anisum L., Foeniculum vulgate, Illicium verum and other plants which are also characterized by the presence of congeners which arise during fermentation process. Trans-anethol and its isomer cis-anethol are the main volatiles and are responsible for aroma properties of these traditional aniseed distillates. The aim of this research work was to find the concentration of special aromatic agent, trans-anethol and cis-anethol and also the major aromatic substances which are responsible for the aromatic quality. The majority of their identified components are isolated by extraction and distillation from different commercial brands and homemade samples. The constituents were identified by GC-MS (gas chromatography-mass spectometry) in this traditional spirit. The major constituents in distilled ouzo extract were also trans-anethol. 展开更多
关键词 Trans-anethol anis distillates ouzo.
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24小时内连出5个变种“ANI蠕虫”制造者发誓今年买宝马
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《计算机与网络》 2007年第7期29-29,共1页
根据瑞星全球反病毒监测网的监测.不久前被截获的“ANI蠕虫”在短短24小时内接连出现5个变种,在互联网上迅速扩散。瑞星反病毒专家介绍说,这些“ANI蠕虫”的变种同样利用上周末才刚出现的Vista、XP等操作系统的ANI高危漏洞.至今微... 根据瑞星全球反病毒监测网的监测.不久前被截获的“ANI蠕虫”在短短24小时内接连出现5个变种,在互联网上迅速扩散。瑞星反病毒专家介绍说,这些“ANI蠕虫”的变种同样利用上周末才刚出现的Vista、XP等操作系统的ANI高危漏洞.至今微软尚未发布针对该漏洞的补丁。由于此病毒传染速度快、威胁较大,瑞星于上周末发出今年第一个“橙色安全警报”(二级)。 展开更多
关键词 ani 蠕虫 变种 小时 制造者 宝马 VISTA 操作系统
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别掉队! TOKYO 这里是ANI SHOW东京国际动画展现场
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《少年人生》 2004年第9期15-22,共8页
2004年3月25日到2004年3月28日。
关键词 国际动画 ani SHOW TOKYO 动画界 毛绒玩具 张井 现场体验 动画形象
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Long range physical map of the Wilms' tumor-aniridia region on human chromosome 11
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作者 D A Compton 《四川生理科学杂志》 2024年第4期923-923,共1页
The relationship between genetic alterations at chromosomal band 11p13 and the WAGR(Wilms'tumor,aniridia,genitourinary anomalies,and mental retardation)syndrome is not clearly understood.To aid our understanding o... The relationship between genetic alterations at chromosomal band 11p13 and the WAGR(Wilms'tumor,aniridia,genitourinary anomalies,and mental retardation)syndrome is not clearly understood.To aid our understanding of this relationship,we have constructed a physical map of this region of the genome using pulsed field gel electrophoresis.Fifteen newly identified 11p13-specific probes and four previously reported probes were used to subdivide 11p13 into five intervals defined by overlapping constitutional deletions from several WAGR patients.This new repertoire of DNA probes was used to construct a physical map of this region using the infrequently cutting restriction enzymes MIuI and NotI.This map spans approximately 13 Mb and encompasses deletion and translocation breakpoints associated with genitourinary abnormalities,aniridia,and Wilms'tumor.The map also makes it possible to localize the genes for Wilms'tumor(WT)and aniridia(AN2)to a small number of specific NotI restriction fragments. 展开更多
关键词 WILMS URINARY ani
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Animator pro与动画片制作
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作者 李剑敏 《电视字幕.特技与动画》 1997年第1期27-29,共3页
随着计算机科学技术的高速发展,计算机动画广泛地应用于日常工作、生活的许多领域,将科学与艺术有机地结合在一起,使得科学具有艺术性。二维动画软件Animatorpro(ANI),以其功能齐全、易于操作、界面友好充分体现出科学性与艺术性的双重... 随着计算机科学技术的高速发展,计算机动画广泛地应用于日常工作、生活的许多领域,将科学与艺术有机地结合在一起,使得科学具有艺术性。二维动画软件Animatorpro(ANI),以其功能齐全、易于操作、界面友好充分体现出科学性与艺术性的双重特点而深受计算机动画制作者的欢迎。 展开更多
关键词 计算机动画 制作 ani
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ANI蠕虫钻Windows漏洞
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作者 沈毅 《少年电脑世界(低年级)》 2007年第6期21-22,共2页
"号外!号外!国家计算机病毒应急处理中心通过对互联网的监测发现‘艾妮’复合型病毒。"侠客略带兴奋的声音在编辑部一角响起。"啥?‘爱你’?好奇怪的名字!"迪迪从电脑前抬起头,苦恼道:"最近病毒可真多,弄得我... "号外!号外!国家计算机病毒应急处理中心通过对互联网的监测发现‘艾妮’复合型病毒。"侠客略带兴奋的声音在编辑部一角响起。"啥?‘爱你’?好奇怪的名字!"迪迪从电脑前抬起头,苦恼道:"最近病毒可真多,弄得我电脑总瘫痪。""这可是个高级病毒,集熊猫烧香、维金两大病毒的特点于一身,是一个传播性与破坏性极强的蠕虫。各位网虫们都小心啦!" 展开更多
关键词 ani WINDOWS 防病毒软件
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Influence of Anisotropic Permeability and Soret Effect on the Convective Heat and Mass Transfer through a Porous Cavity Saturated by a Non-Newtonian Fluid
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作者 Dieudonné Kouke Julien Yovogan 《Engineering(科研)》 2023年第12期843-866,共24页
In this work, an analytical study is carried out on double-diffusive natural convection through a horizontal anisotropic porous layer saturated with a non-Newtonian fluid by using the Darcy model with the Boussinesq a... In this work, an analytical study is carried out on double-diffusive natural convection through a horizontal anisotropic porous layer saturated with a non-Newtonian fluid by using the Darcy model with the Boussinesq approximations. The horizontal walls of the system are subject to vertical uniform fluxes of heat and mass, whereas the vertical walls are assumed to be adiabatic and impermeable. The Soret effect is taken into consideration. Based on parallel flow approximation theory, the problem is solved in the limit of a thin layer and documented the effects of the physical parameters describing this investigation. 展开更多
关键词 Soret Number Heat and Mass Transfer Non-Newtonian Fluid ISOTROPY ani-sotropy Supercritical Rayleigh Number
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Late Middle Pleistocene Harbin cranium represents a new Homo species 被引量:5
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作者 Qiang Ji Wensheng Wu +2 位作者 Yannan Ji Qiang Li Xijun Ni 《The Innovation》 2021年第3期3-4,共2页
In eastern Asia,several Middle-Late Pleistocene human fossils,such as the Dali,Jinniushan,Hualongdong,and Harbin crania,evidently resemble each other and are phylogenetically closer to H.sapiens than to H.neanderthale... In eastern Asia,several Middle-Late Pleistocene human fossils,such as the Dali,Jinniushan,Hualongdong,and Harbin crania,evidently resemble each other and are phylogenetically closer to H.sapiens than to H.neanderthalensis or other archaic humans.1 The Harbin cranium is the best preserved of this group.It shows a mosaic combination of plesiomorphic and apomorphic features.Here,we suggest that the Harbin skull should be recognized as a new species of Homo. 展开更多
关键词 MIDDLE CLOSER ani
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Identification of novel mutations in EYA3 and EFTUD2 in a family with craniofacial microsomia:evidence of digenic inheritance
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作者 Nuo Si Guoqin Zhan +3 位作者 Xiaolu Meng Zeya Zhang Xin Huang Bo Pan 《Frontiers of Medicine》 SCIE CSCD 2023年第5期1006-1009,共4页
Dear Editor,Craniofacial microsomia(CFM,MIM#164210)is a congenital malformation involving the first and second branchial arch derivatives.The phenotype of CFM is highly variable and typically affects the external ear,... Dear Editor,Craniofacial microsomia(CFM,MIM#164210)is a congenital malformation involving the first and second branchial arch derivatives.The phenotype of CFM is highly variable and typically affects the external ear,middle ear,mandible and temporomandibular joint,and facial muscles on the affected side.Accompanied by craniofacial anomalies,cardiac,vertebral,and central nervous system defects may occur.Microtia is considered the minimum diagnostic criterion[1,2]. 展开更多
关键词 ani CONGENITAL VERTEBRAL
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Turning constraint into opportunity: development of a four-component Catellani reaction
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作者 Hong-Gang Cheng Qianghui Zhou 《Science Bulletin》 SCIE EI CSCD 2020年第23期1961-1963,共3页
Polyfunctional arenes are key structural scaffolds commonly found in natural products, pharmaceuticals, fine chemicals and materials [1]. As such, the development of rapid and efficient methods to functionalize these ... Polyfunctional arenes are key structural scaffolds commonly found in natural products, pharmaceuticals, fine chemicals and materials [1]. As such, the development of rapid and efficient methods to functionalize these scaffolds has received substantial attention, leading to the development of several elegant synthetic strategies. Among these methods, the Catellani reaction。 展开更多
关键词 ani 四组分 strategies.
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基于任意设站控制网的地铁轨道控制网测量研究
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作者 付强 《科学技术创新》 2026年第3期53-56,共4页
为了提升地铁轨道控制网的测量精度与效率,通过介绍多方向后方交会任意设站法的原理与设计,分析了该方法在地铁隧道复杂环境下的适用性,提出了一种优化的控制网布设方案。研究内容包括任意设站控制网联测高等级线路控制网的形式设计、... 为了提升地铁轨道控制网的测量精度与效率,通过介绍多方向后方交会任意设站法的原理与设计,分析了该方法在地铁隧道复杂环境下的适用性,提出了一种优化的控制网布设方案。研究内容包括任意设站控制网联测高等级线路控制网的形式设计、三角高程测量方法、平面与高程数据处理流程,以及区段间测量数据的衔接处理方法,并采用严格的测量结果检验标准验证其可靠性。研究结果表明:基于任意设站控制网的测量方法能够有效克服隧道内通视条件差、传统水准测量困难等问题,提高控制网的整体精度和稳定性,满足地铁轨道施工的高平顺性要求,为类似工程提供可行的技术参考。 展开更多
关键词 任意设站 控制网 地铁 轨道 高程 测量
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