In this paper,we study the three-dimensional regularized MHD equations with fractional Laplacians in the dissipative and diffusive terms.We establish the global existence of mild solutions to this system with small in...In this paper,we study the three-dimensional regularized MHD equations with fractional Laplacians in the dissipative and diffusive terms.We establish the global existence of mild solutions to this system with small initial data.In addition,we also obtain the Gevrey class regularity and the temporal decay rate of the solution.展开更多
On a complete non-compact gradient shrinking Ricci soliton,we prove the analyticity in time for smooth solutions of the heat equation with quadratic exponential growth in the space variable.This growth condition is sh...On a complete non-compact gradient shrinking Ricci soliton,we prove the analyticity in time for smooth solutions of the heat equation with quadratic exponential growth in the space variable.This growth condition is sharp.As an application,we give a necessary and sufficient condition on the solvability of the backward heat equation in a class of functions with quadratic exponential growth on shrinkers.展开更多
In this paper we prove the analyticity of the semigroups generated by some singular differential matrix operators of the form in the Banach space with suitable boundary conditions. To illustrate the work an example is...In this paper we prove the analyticity of the semigroups generated by some singular differential matrix operators of the form in the Banach space with suitable boundary conditions. To illustrate the work an example is discussed.展开更多
In this paper we are interested in studying the dissipativity of degenerate mixed differential operators involving an interface point. We show that, under particular interface conditions, such operators generate analy...In this paper we are interested in studying the dissipativity of degenerate mixed differential operators involving an interface point. We show that, under particular interface conditions, such operators generate analytic semigroups on an appropriate Hilbert space . To illustrate the results an example is discussed.展开更多
In this paper,we study the problem of analyticity of smooth solutions of the inviscid Boussinesq equations.If the initial datum is real-analytic,the solution remains real-analytic on the existence interval.By an induc...In this paper,we study the problem of analyticity of smooth solutions of the inviscid Boussinesq equations.If the initial datum is real-analytic,the solution remains real-analytic on the existence interval.By an inductive method we can obtain a lower bound on the radius of spatial analyticity of the smooth solution.展开更多
We consider a thermoelastic plate with dynamical boundary conditions. Using the contradictionargument of Pazy's well-known analyticity criterion and P.D.E. estimates, we prove that the corresponding C0semigroup is...We consider a thermoelastic plate with dynamical boundary conditions. Using the contradictionargument of Pazy's well-known analyticity criterion and P.D.E. estimates, we prove that the corresponding C0semigroup is analytic, hence exponentially stable.展开更多
In the present paper,the analyticity of solutions to a class of degenerate elliptic equations is obtained.A kind of weighted norms are introduced and under such norms some degenerate elliptic operators are of weak coe...In the present paper,the analyticity of solutions to a class of degenerate elliptic equations is obtained.A kind of weighted norms are introduced and under such norms some degenerate elliptic operators are of weak coerciveness.展开更多
If the second order problem u（t） ＋ Bu（t） ＋ Au（t） = f（t）, u（0） =u（0） = 0 has L^p-maximal regularity, 1 〈 p 〈 ∞, the analyticity of the corresponding propagator of the sine type is shown by obtaining th...If the second order problem u（t） ＋ Bu（t） ＋ Au（t） = f（t）, u（0） =u（0） = 0 has L^p-maximal regularity, 1 〈 p 〈 ∞, the analyticity of the corresponding propagator of the sine type is shown by obtaining the estimates of ‖λ（λ^2 ＋ λB ＋ A）^-1‖ and ‖B（λ^2 ＋ λB ＋ A）^-1‖ for λ∈ C with Reλ 〉 ω, where the constant ω≥ 0.展开更多
The Cauchy problem for the 3D incompressible magneto-hydrodynamics equations in crit- cal spaces is considered. We first prove the global well-posedness of mild solution for the system in some time dependent spaces. F...The Cauchy problem for the 3D incompressible magneto-hydrodynamics equations in crit- cal spaces is considered. We first prove the global well-posedness of mild solution for the system in some time dependent spaces. Furthermore, we obtain analyticity of the solution.展开更多
Given initial data u0 ∈ L^(p)(R^(3)) for some p in [3,18/5 [,the auhtors first prove that3 D incompressible Navier-Stokes system has a unique solution μ=μL+v with μL=^(def)e^(t△)μ_(0) and ν∈L^(∞)([0,T];H^(5/2...Given initial data u0 ∈ L^(p)(R^(3)) for some p in [3,18/5 [,the auhtors first prove that3 D incompressible Navier-Stokes system has a unique solution μ=μL+v with μL=^(def)e^(t△)μ_(0) and ν∈L^(∞)([0,T];H^(5/2)-^(6/p)∩L^(1)([0,T];H^(9/2-6/p) for some positive time T.Then they derive an explicit lower bound for the radius of space analyticity of v,which in particular extends the corresponding results in [Chemin,J.-Y.,Gallagher,I.and Zhang,P.,On the radius of analyticity of solutions to semi-linear parabolic system,Math.Res.Lett.,27,2020,1631-1643,Herbst,I.and Skibsted,E.,Analyticity estimates for the Navier-Stokes equations,Adv.in Math.,228,2011,1990-2033] with initial data in H^(s)(R^(3)) for s ∈ [1/2,3/2[.展开更多
Promoting urban-rural integration and facilitating the bidirectional flow of urban and rural elements are core spatial objectives in the new era of China.The urban-rural fringe represents the region with the most inte...Promoting urban-rural integration and facilitating the bidirectional flow of urban and rural elements are core spatial objectives in the new era of China.The urban-rural fringe represents the region with the most intense interaction between urban and rural areas,serving as a key zone for breaking down barriers and promoting urban-rural integration.Based on a systematic review of representative case studies and scholarly literature,this paper synthesizes the evolving research perspectives on the urban-rural fringe,with particular attention to how data-driven approaches that integrate official statistics,remote sensing imagery,points of interest,and mobile phone signaling data have advanced the characterization of fringe features,refined identification methods,and revealed emerging developmental trends through spatial clustering and machine learning classification.It proposes an integrated analytical framework encompassing administrative boundaries,economic metabolism,social activities,material infrastructure,and the ecological environment.The paper further examines the characteristics and emerging development trends of urban-rural fringe areas and advances a set of strategic directions to support urban-rural integration and more efficient resource allocation.These include expanding analytical dimensions,enhancing data integration,refining identification criteria,elucidating mechanisms of internal and external interactions,and strengthening interdisciplinary collaboration.Collectively,these efforts offer actionable insights for optimizing public service delivery,directing infrastructure investment in transportation and utilities,delineating ecological conservation boundaries,and implementing place-based socioeconomic revitalization strategies in the urban-rural fringe regions.展开更多
Chinese Chemical Letters(CCL)(ISSN 1001-8417)was founded in July 1990.The journal publishes preliminary accounts in the whole field of chemistry,including inorganic chemistry,organic chemistry,analytical chemistry,phy...Chinese Chemical Letters(CCL)(ISSN 1001-8417)was founded in July 1990.The journal publishes preliminary accounts in the whole field of chemistry,including inorganic chemistry,organic chemistry,analytical chemistry,physical chemistry,polymer chemistry,applied chemistry,etc.,satisfying a real and urgent need for the dissemination of research results,especially hot topics.The journal does not accept articles previously published or scheduled to be published.To verify originality,your article may be checked by the originality detection service Cross Check.展开更多
Oil-fired construction machinery(OCM)is a major source of urban air pollutants and CO_(2) emissions,and elec-trification is a crucial pathway for improving air quality and achieving China’s dual carbon goals;however,...Oil-fired construction machinery(OCM)is a major source of urban air pollutants and CO_(2) emissions,and elec-trification is a crucial pathway for improving air quality and achieving China’s dual carbon goals;however,its feasibility has not been fully explored.This study uses data envelopment analysis and the analytic hierarchy process to establish a development potential index,covering technical efficiency,economic cost,application sce-narios,and charging time and range,with an empirical analysis conducted in Beijing.The findings indicated the high feasibility of replacing OCM with electric alternatives,especially within the low-power range.Based on 2023 registered coding dat1,it is projected that by 2030,electrification could reduce regional average con-centrations of CO,NO_(x),PM_(2.5) and VOCs by 12.2%to 56.4%and reduce CO_(2) by 11.7%to 56.9%.Owing to economic considerations,small-and medium-sized machinery are particularly feasible for electrification.Key recommendations include prioritizing the electrification of forklifts,lifting platforms,and small-sized machinery in high-emission areas,particularly in central urban districts.Policies such as carbon taxes,carbon markets,and performance grading systems are suggested to incentivize electrification,along with expanding high-emission restriction zones and improving energy infrastructure to support widespread electrification.展开更多
This study examines the hemodynamics of non-Newtonian blood flow in stenosed arteries,focusing on the roles of stenosis severity,guidewire presence,and various non-Newtonian constitutive models.Computational simulatio...This study examines the hemodynamics of non-Newtonian blood flow in stenosed arteries,focusing on the roles of stenosis severity,guidewire presence,and various non-Newtonian constitutive models.Computational simulations using the generalized power-law,Casson,and Carreau-Yasuda models are conducted for stenosis severities of 50%,70%,80%,and 90%.Results indicate that stenosis severity exerts the greatest influence on pressure and wall shear stress(WSS),with increasing severity leading to higher pressure drops and WSS maxima.Guidewire presence reduces recirculation zone lengths by nearly 60%across different severities and raises the trans-stenotic pressure drop up to 120%.While the choice of constitutive model has minimal impact on hemodynamics within the stenotic region,it becomes crucial in healthy vessels,where non-Newtonian effects are more pronounced.In cases with a guidewire,pressure gradients in the healthy region show up to 18.8%differences between non-Newtonian models.These findings highlight the dominant roles of stenosis severity and guidewire presence in shaping hemodynamics within stenotic regions while emphasizing the need for precise constitutive modeling to capture flow characteristics in healthy vascular segments.展开更多
Strong seismic excitation and fault dislocation are likely to occur simultaneously in high-intensity seismic zones,causing severe damage to tunnels crossing active fault zones.This paper aims to develop a novel analyt...Strong seismic excitation and fault dislocation are likely to occur simultaneously in high-intensity seismic zones,causing severe damage to tunnels crossing active fault zones.This paper aims to develop a novel analytical solution to determine the longitudinal mechanical responses of tunnels subjected to the combined effects of seismic waves and strike-slip faulting.Adopting the elastic springbeam model,the seismic waves are modelled as shear horizontal(SH)waves and the fault dislocation follows an S-shaped pattern;the superposition principle for free-fielddisplacements caused by both effects is assumed.In addition,the transmission and reflectionof seismic waves at the fault-rock geological interface and the tangential contact conditions at the tunnel-rock interface are considered.The analytical model is validated against numerical simulations,confirmingits accuracy in calculating tunnel responses.Moreover,a parametric study is conducted to evaluate the impact of key factors,including fault displacement,fault zone width,fault dip angle,earthquake frequency,rock conditions,tunnel lining stiffness,and tangential contact conditions,on tunnel responses.Compared with each effect alone,the combined effects of seismic waves and strike-slip faulting significantlychange the tunnel deformation and internal forces,leading to increased tunnel responses,especially within the fault zone and near the fault-rock interfaces.Depending on specificparameters,tunnel responses can be classifiedinto seismic-dominated,faulting-dominated,and seismic-faulting coupled responses on the basis of the relative contributions of each effect.The proposed analytical solution can be applied to quickly predict the longitudinal mechanical behaviour of tunnels under such combined effects in engineering applications.展开更多
Small extracellular vesicles(sEVs)membrane protein profile(sEVpp)is a novel biomarker for cancer,and it can reveal the in-depth phenotype information.The point-of-care testing(POCT)of sEVpp holds great significance fo...Small extracellular vesicles(sEVs)membrane protein profile(sEVpp)is a novel biomarker for cancer,and it can reveal the in-depth phenotype information.The point-of-care testing(POCT)of sEVpp holds great significance for mass screening of cancer,so the cost-effective and simple detection methods of sEVpp are urgently demanded.Herein,we constructed a paper-based multichannel sEVpp POCT device(sEVpp-PAD)enabled by functional DNA probes and metal-organic framework(MOF).The core components are aptamer/MOF-modified paper chips.The modified aptamers can immunocapture the sEV expressing corresponding proteins,while the modified MOF can provide abundant sites for aptamer-modification,reduce the nonspecific protein absorption,and act as reference for ratiometric detection.Simply powered by two syringes,the sEVpp-PAD can efficiently capture sEVs expressing corresponding protein from cell culture media and sera.Furthermore,a detection probe(DP)consisted of CD63 aptamer and G-quadruplex was developed for the colorimetric detection of captured sEVs.Utilizing this device,the sEVpp in various hepatocellular carcinoma cell culture medium and,more importantly,in human sera can be accurately determined,only with$2 device,$0.2 detection reagents and 1.8 h procedure.This simple strategy for sEVpp detection can innovatively promote the POCT and subtyping of cancer based on sEV-related liquid biopsy.展开更多
Ganmai Dazao Decoction,originating from“Jin Gui Yao Lue”(Synopsis of the Golden Chamber),is a classical prescription for treating visceral agitation.Composed of three medicinal and edible substances-licorice(Gancao)...Ganmai Dazao Decoction,originating from“Jin Gui Yao Lue”(Synopsis of the Golden Chamber),is a classical prescription for treating visceral agitation.Composed of three medicinal and edible substances-licorice(Gancao),wheat(Xiaomai),and jujube(Dazao),it functions to nourish the heart and calm the mind,harmonize the middle burner and regulate Qi,and alleviate urgency and restlessness.As its clinical application has expanded from traditional emotional disorders to neurological,endocrine,and various psychosomatic diseases,establishing a scientifically precise quality control system and deeply elucidating its pharmacodynamic material basis and mechanism of action have become critical tasks.Modern analytical methods,typified by chromatography,spectroscopy,and their hyphenated techniques,with their high sensitivity,high resolution,and powerful substance characterization capabilities,have become the core driving force for standardizing the quality control and modernizing the clinical application research of this formula.This paper systematically reviews the progress of the aforementioned analytical techniques and chemometrics in interpreting the chemical composition,establishing fingerprint profiles,controlling process quality,and researching the pharmacodynamic material basis of Ganmai Dazao Decoction.Furthermore,it discusses integrated approaches combining analytical techniques with pharmacology and clinical medicine to reveal mechanisms of action and explore therapeutic biomarkers.Finally,it provides an outlook on future directions and challenges,including technological integration and innovation,standardization of whole-process quality control systems,and evidence-based research aimed at internationalization.展开更多
Operating Lithium-ion batteries at their temperature limits is a challenging design task due to explosion risk at high temperatures and rapid degradation at low temperatures.Depending on the battery package design,tho...Operating Lithium-ion batteries at their temperature limits is a challenging design task due to explosion risk at high temperatures and rapid degradation at low temperatures.Depending on the battery package design,those risks can be solved with passive solutions,which require no active cooling or heating.Thecurrentwork aims to optimize the pack design and materials of the type-NCR18650B battery based on a wide range of operation temperature.The lower limit was denoted by cold case while the maximum limit was expressed by hot case.A combined analyticalnumerical approach was developed to model the heat generation inside the battery.A thermal resistance analysis was used to determine the boundary conditions of the numerical model.The governing differential equations for the 1-D heat generation model were solved analytically.The numerical analysis was considered to determine the best battery pack design based on material parameters,number of batteries,and geometrical arrangement.The analytical results revealedthat the cold case canbe selectedas theworst case and thebestmodel wasobtainedusing thehexagonal-shaped 10-battery pack that was covered with Delrin of 1.8 mm in thickness.The numerical results showed that the best model was the hexagonal-shaped 10-battery pack with Delrin of 2 mm in thickness that achieved the largest temperature of−20.6℃ in the cold case.展开更多
In the competitive retail industry of the digital era,data-driven insights into gender-specific customer behavior are essential.They support the optimization of store performance,layout design,product placement,and ta...In the competitive retail industry of the digital era,data-driven insights into gender-specific customer behavior are essential.They support the optimization of store performance,layout design,product placement,and targeted marketing.However,existing computer vision solutions often rely on facial recognition to gather such insights,raising significant privacy and ethical concerns.To address these issues,this paper presents a privacypreserving customer analytics system through two key strategies.First,we deploy a deep learning framework using YOLOv9s,trained on the RCA-TVGender dataset.Cameras are positioned perpendicular to observation areas to reduce facial visibility while maintaining accurate gender classification.Second,we apply AES-128 encryption to customer position data,ensuring secure access and regulatory compliance.Our system achieved overall performance,with 81.5%mAP@50,77.7%precision,and 75.7%recall.Moreover,a 90-min observational study confirmed the system’s ability to generate privacy-protected heatmaps revealing distinct behavioral patterns between male and female customers.For instance,women spent more time in certain areas and showed interest in different products.These results confirm the system’s effectiveness in enabling personalized layout and marketing strategies without compromising privacy.展开更多
Latest digital advancements have intensified the necessity for adaptive,data-driven and socially-centered learning ecosystems.This paper presents the formulation of a cross-platform,innovative,gamified and personalize...Latest digital advancements have intensified the necessity for adaptive,data-driven and socially-centered learning ecosystems.This paper presents the formulation of a cross-platform,innovative,gamified and personalized Learning Ecosystem,which integrates 3D/VR environments,as well as machine learning algorithms,and business intelligence frameworks to enhance learner-centered education and inferenced decision-making.This Learning System makes use of immersive,analytically assessed virtual learning spaces,therefore facilitating real-time monitoring of not just learning performance,but also overall engagement and behavioral patterns,via a comprehensive set of sustainability-oriented ESG-aligned Key Performance Indicators(KPIs).Machine learning models support predictive analysis,personalized feedback,and hybrid recommendation mechanisms,whilst dedicated dashboards translate complex educational data into actionable insights for all Use Cases of the System(Educational Institutions,Educators and Learners).Additionally,the presented Learning System introduces a structured Mentoring and Consulting Subsystem,thence reinforcing human-centered guidance alongside automated intelligence.The Platform’s modular architecture and simulation-centered evaluation approach actively support personalized,and continuously optimized learning pathways.Thence,it exemplifies a mature,adaptive Learning Ecosystem,supporting immersive technologies,analytics,and pedagogical support,hence,contributing to contemporary digital learning innovation and sociotechnical transformation in education.展开更多
基金supported by the Opening Project of Guangdong Province Key Laboratory of Cyber-Physical System(20168030301008)supported by the National Natural Science Foundation of China(11126266)+4 种基金the Natural Science Foundation of Guangdong Province(2016A030313390)the Quality Engineering Project of Guangdong Province(SCAU-2021-69)the SCAU Fund for High-level University Buildingsupported by the National Key Research and Development Program of China(2020YFA0712500)the National Natural Science Foundation of China(11971496,12126609)。
文摘In this paper,we study the three-dimensional regularized MHD equations with fractional Laplacians in the dissipative and diffusive terms.We establish the global existence of mild solutions to this system with small initial data.In addition,we also obtain the Gevrey class regularity and the temporal decay rate of the solution.
基金partially supported by the National Natural Science Foundation of China(11671141)the Natural Science Foundation of Shanghai(17ZR1412800)。
文摘On a complete non-compact gradient shrinking Ricci soliton,we prove the analyticity in time for smooth solutions of the heat equation with quadratic exponential growth in the space variable.This growth condition is sharp.As an application,we give a necessary and sufficient condition on the solvability of the backward heat equation in a class of functions with quadratic exponential growth on shrinkers.
文摘In this paper we prove the analyticity of the semigroups generated by some singular differential matrix operators of the form in the Banach space with suitable boundary conditions. To illustrate the work an example is discussed.
文摘In this paper we are interested in studying the dissipativity of degenerate mixed differential operators involving an interface point. We show that, under particular interface conditions, such operators generate analytic semigroups on an appropriate Hilbert space . To illustrate the results an example is discussed.
基金supported partially by"The Fundamental Research Funds for Central Universities of China".
文摘In this paper,we study the problem of analyticity of smooth solutions of the inviscid Boussinesq equations.If the initial datum is real-analytic,the solution remains real-analytic on the existence interval.By an inductive method we can obtain a lower bound on the radius of spatial analyticity of the smooth solution.
基金This work was supported by the National Natural Science Foundation of China(Grant No.10071079).
文摘We consider a thermoelastic plate with dynamical boundary conditions. Using the contradictionargument of Pazy's well-known analyticity criterion and P.D.E. estimates, we prove that the corresponding C0semigroup is analytic, hence exponentially stable.
文摘In the present paper,the analyticity of solutions to a class of degenerate elliptic equations is obtained.A kind of weighted norms are introduced and under such norms some degenerate elliptic operators are of weak coerciveness.
基金Supported by National Natural Science Foundation of China (Grant No. 10672062)
文摘If the second order problem u（t） ＋ Bu（t） ＋ Au（t） = f（t）, u（0） =u（0） = 0 has L^p-maximal regularity, 1 〈 p 〈 ∞, the analyticity of the corresponding propagator of the sine type is shown by obtaining the estimates of ‖λ（λ^2 ＋ λB ＋ A）^-1‖ and ‖B（λ^2 ＋ λB ＋ A）^-1‖ for λ∈ C with Reλ 〉 ω, where the constant ω≥ 0.
基金Supported by Research supported by the National Natural Science Foundation of China(Grant Nos.11501332,11771043,11371221)the Natural Science Foundation of Shandong Province(Grant No.ZR2015AL007)+4 种基金China Postdoctoral Science Foundation funded project(Grant No.2014M561893)Postdoctoral innovation fund of Shandong Province(Grant No.201502015)the Open Fund of State Key Laboratory of Simulation and Regulation of Water Cycle in River Basin,China Institute of Water Resources and Hydropower Research Fund(Grant No.IWHR-SKL-201407)the Specialized Research Foundation for the Doctoral Program of Higher Education of China(Grant No.20123705110001)Young Scholars Research Fund of Shandong University of Technology
文摘The Cauchy problem for the 3D incompressible magneto-hydrodynamics equations in crit- cal spaces is considered. We first prove the global well-posedness of mild solution for the system in some time dependent spaces. Furthermore, we obtain analyticity of the solution.
基金supported by the National Natural Science Foundation of China(Nos.11731007,12031006,11688101)the National Key R&D Program of China(No.2021YFA1000800)K.C.Wong Education Foundation。
文摘Given initial data u0 ∈ L^(p)(R^(3)) for some p in [3,18/5 [,the auhtors first prove that3 D incompressible Navier-Stokes system has a unique solution μ=μL+v with μL=^(def)e^(t△)μ_(0) and ν∈L^(∞)([0,T];H^(5/2)-^(6/p)∩L^(1)([0,T];H^(9/2-6/p) for some positive time T.Then they derive an explicit lower bound for the radius of space analyticity of v,which in particular extends the corresponding results in [Chemin,J.-Y.,Gallagher,I.and Zhang,P.,On the radius of analyticity of solutions to semi-linear parabolic system,Math.Res.Lett.,27,2020,1631-1643,Herbst,I.and Skibsted,E.,Analyticity estimates for the Navier-Stokes equations,Adv.in Math.,228,2011,1990-2033] with initial data in H^(s)(R^(3)) for s ∈ [1/2,3/2[.
基金Under the auspices of the Funding Project of Northeast Geological S&T Innovation Center of China Geological Survey(No.QCJJ2024-11)Natural Science Foundation of Liaoning Province(No.2025-BS-0873)+1 种基金Liaoning Provincial Joint Science and Technology Program(No.2024-MSLH-507)National Social Science Foundation of China(No.23ATJ006)。
文摘Promoting urban-rural integration and facilitating the bidirectional flow of urban and rural elements are core spatial objectives in the new era of China.The urban-rural fringe represents the region with the most intense interaction between urban and rural areas,serving as a key zone for breaking down barriers and promoting urban-rural integration.Based on a systematic review of representative case studies and scholarly literature,this paper synthesizes the evolving research perspectives on the urban-rural fringe,with particular attention to how data-driven approaches that integrate official statistics,remote sensing imagery,points of interest,and mobile phone signaling data have advanced the characterization of fringe features,refined identification methods,and revealed emerging developmental trends through spatial clustering and machine learning classification.It proposes an integrated analytical framework encompassing administrative boundaries,economic metabolism,social activities,material infrastructure,and the ecological environment.The paper further examines the characteristics and emerging development trends of urban-rural fringe areas and advances a set of strategic directions to support urban-rural integration and more efficient resource allocation.These include expanding analytical dimensions,enhancing data integration,refining identification criteria,elucidating mechanisms of internal and external interactions,and strengthening interdisciplinary collaboration.Collectively,these efforts offer actionable insights for optimizing public service delivery,directing infrastructure investment in transportation and utilities,delineating ecological conservation boundaries,and implementing place-based socioeconomic revitalization strategies in the urban-rural fringe regions.
文摘Chinese Chemical Letters(CCL)(ISSN 1001-8417)was founded in July 1990.The journal publishes preliminary accounts in the whole field of chemistry,including inorganic chemistry,organic chemistry,analytical chemistry,physical chemistry,polymer chemistry,applied chemistry,etc.,satisfying a real and urgent need for the dissemination of research results,especially hot topics.The journal does not accept articles previously published or scheduled to be published.To verify originality,your article may be checked by the originality detection service Cross Check.
基金supported by the National Science and Technology Major Project of the Ministry of Science and Technology of China(No.2024ZD1200200).
文摘Oil-fired construction machinery(OCM)is a major source of urban air pollutants and CO_(2) emissions,and elec-trification is a crucial pathway for improving air quality and achieving China’s dual carbon goals;however,its feasibility has not been fully explored.This study uses data envelopment analysis and the analytic hierarchy process to establish a development potential index,covering technical efficiency,economic cost,application sce-narios,and charging time and range,with an empirical analysis conducted in Beijing.The findings indicated the high feasibility of replacing OCM with electric alternatives,especially within the low-power range.Based on 2023 registered coding dat1,it is projected that by 2030,electrification could reduce regional average con-centrations of CO,NO_(x),PM_(2.5) and VOCs by 12.2%to 56.4%and reduce CO_(2) by 11.7%to 56.9%.Owing to economic considerations,small-and medium-sized machinery are particularly feasible for electrification.Key recommendations include prioritizing the electrification of forklifts,lifting platforms,and small-sized machinery in high-emission areas,particularly in central urban districts.Policies such as carbon taxes,carbon markets,and performance grading systems are suggested to incentivize electrification,along with expanding high-emission restriction zones and improving energy infrastructure to support widespread electrification.
基金supported by the National Key Research and Development Program of China(Grant Nos.2021YFA1000200 and 2021YFA1000201)National Natural Science Foundation of China(Grant Nos.12293001 and 12272009)+1 种基金Beijing Natural Science Foundation,China(Grant No.7232050)the Shenzhen Science and Technology Research and Development Grant,China(Grant No.KQTD20180411143400981).
文摘This study examines the hemodynamics of non-Newtonian blood flow in stenosed arteries,focusing on the roles of stenosis severity,guidewire presence,and various non-Newtonian constitutive models.Computational simulations using the generalized power-law,Casson,and Carreau-Yasuda models are conducted for stenosis severities of 50%,70%,80%,and 90%.Results indicate that stenosis severity exerts the greatest influence on pressure and wall shear stress(WSS),with increasing severity leading to higher pressure drops and WSS maxima.Guidewire presence reduces recirculation zone lengths by nearly 60%across different severities and raises the trans-stenotic pressure drop up to 120%.While the choice of constitutive model has minimal impact on hemodynamics within the stenotic region,it becomes crucial in healthy vessels,where non-Newtonian effects are more pronounced.In cases with a guidewire,pressure gradients in the healthy region show up to 18.8%differences between non-Newtonian models.These findings highlight the dominant roles of stenosis severity and guidewire presence in shaping hemodynamics within stenotic regions while emphasizing the need for precise constitutive modeling to capture flow characteristics in healthy vascular segments.
基金supported by the National Natural Science Foundation of China(No.41941018)Shanghai Gaofeng Discipline Construction Funding.
文摘Strong seismic excitation and fault dislocation are likely to occur simultaneously in high-intensity seismic zones,causing severe damage to tunnels crossing active fault zones.This paper aims to develop a novel analytical solution to determine the longitudinal mechanical responses of tunnels subjected to the combined effects of seismic waves and strike-slip faulting.Adopting the elastic springbeam model,the seismic waves are modelled as shear horizontal(SH)waves and the fault dislocation follows an S-shaped pattern;the superposition principle for free-fielddisplacements caused by both effects is assumed.In addition,the transmission and reflectionof seismic waves at the fault-rock geological interface and the tangential contact conditions at the tunnel-rock interface are considered.The analytical model is validated against numerical simulations,confirmingits accuracy in calculating tunnel responses.Moreover,a parametric study is conducted to evaluate the impact of key factors,including fault displacement,fault zone width,fault dip angle,earthquake frequency,rock conditions,tunnel lining stiffness,and tangential contact conditions,on tunnel responses.Compared with each effect alone,the combined effects of seismic waves and strike-slip faulting significantlychange the tunnel deformation and internal forces,leading to increased tunnel responses,especially within the fault zone and near the fault-rock interfaces.Depending on specificparameters,tunnel responses can be classifiedinto seismic-dominated,faulting-dominated,and seismic-faulting coupled responses on the basis of the relative contributions of each effect.The proposed analytical solution can be applied to quickly predict the longitudinal mechanical behaviour of tunnels under such combined effects in engineering applications.
基金supported by the National Key Research and Development Program of China(No.2022YFE0201800)the National Natural Science Foundation of China(Nos.22274169 and 22474161)+5 种基金Guangdong Basic and Applied Basic Research Foundation(No.2024A1515030160)the Science and Technology Program of Guangzhou City(No.2023B03J1380)Shenzhen Science and Technology Innovation Commission(No.GJHZ20210705142200001)the Scientific Technology Project of Guangzhou City(No.202103000003)the Guangdong Science and Technology Plan Project(No.2020B1212060077)the Open Research Fund of State Key Laboratory of Analytical Chemistry for Life Science,School of Chemistry and Chemical Engineering,Nanjing University.
文摘Small extracellular vesicles(sEVs)membrane protein profile(sEVpp)is a novel biomarker for cancer,and it can reveal the in-depth phenotype information.The point-of-care testing(POCT)of sEVpp holds great significance for mass screening of cancer,so the cost-effective and simple detection methods of sEVpp are urgently demanded.Herein,we constructed a paper-based multichannel sEVpp POCT device(sEVpp-PAD)enabled by functional DNA probes and metal-organic framework(MOF).The core components are aptamer/MOF-modified paper chips.The modified aptamers can immunocapture the sEV expressing corresponding proteins,while the modified MOF can provide abundant sites for aptamer-modification,reduce the nonspecific protein absorption,and act as reference for ratiometric detection.Simply powered by two syringes,the sEVpp-PAD can efficiently capture sEVs expressing corresponding protein from cell culture media and sera.Furthermore,a detection probe(DP)consisted of CD63 aptamer and G-quadruplex was developed for the colorimetric detection of captured sEVs.Utilizing this device,the sEVpp in various hepatocellular carcinoma cell culture medium and,more importantly,in human sera can be accurately determined,only with$2 device,$0.2 detection reagents and 1.8 h procedure.This simple strategy for sEVpp detection can innovatively promote the POCT and subtyping of cancer based on sEV-related liquid biopsy.
文摘Ganmai Dazao Decoction,originating from“Jin Gui Yao Lue”(Synopsis of the Golden Chamber),is a classical prescription for treating visceral agitation.Composed of three medicinal and edible substances-licorice(Gancao),wheat(Xiaomai),and jujube(Dazao),it functions to nourish the heart and calm the mind,harmonize the middle burner and regulate Qi,and alleviate urgency and restlessness.As its clinical application has expanded from traditional emotional disorders to neurological,endocrine,and various psychosomatic diseases,establishing a scientifically precise quality control system and deeply elucidating its pharmacodynamic material basis and mechanism of action have become critical tasks.Modern analytical methods,typified by chromatography,spectroscopy,and their hyphenated techniques,with their high sensitivity,high resolution,and powerful substance characterization capabilities,have become the core driving force for standardizing the quality control and modernizing the clinical application research of this formula.This paper systematically reviews the progress of the aforementioned analytical techniques and chemometrics in interpreting the chemical composition,establishing fingerprint profiles,controlling process quality,and researching the pharmacodynamic material basis of Ganmai Dazao Decoction.Furthermore,it discusses integrated approaches combining analytical techniques with pharmacology and clinical medicine to reveal mechanisms of action and explore therapeutic biomarkers.Finally,it provides an outlook on future directions and challenges,including technological integration and innovation,standardization of whole-process quality control systems,and evidence-based research aimed at internationalization.
文摘Operating Lithium-ion batteries at their temperature limits is a challenging design task due to explosion risk at high temperatures and rapid degradation at low temperatures.Depending on the battery package design,those risks can be solved with passive solutions,which require no active cooling or heating.Thecurrentwork aims to optimize the pack design and materials of the type-NCR18650B battery based on a wide range of operation temperature.The lower limit was denoted by cold case while the maximum limit was expressed by hot case.A combined analyticalnumerical approach was developed to model the heat generation inside the battery.A thermal resistance analysis was used to determine the boundary conditions of the numerical model.The governing differential equations for the 1-D heat generation model were solved analytically.The numerical analysis was considered to determine the best battery pack design based on material parameters,number of batteries,and geometrical arrangement.The analytical results revealedthat the cold case canbe selectedas theworst case and thebestmodel wasobtainedusing thehexagonal-shaped 10-battery pack that was covered with Delrin of 1.8 mm in thickness.The numerical results showed that the best model was the hexagonal-shaped 10-battery pack with Delrin of 2 mm in thickness that achieved the largest temperature of−20.6℃ in the cold case.
文摘In the competitive retail industry of the digital era,data-driven insights into gender-specific customer behavior are essential.They support the optimization of store performance,layout design,product placement,and targeted marketing.However,existing computer vision solutions often rely on facial recognition to gather such insights,raising significant privacy and ethical concerns.To address these issues,this paper presents a privacypreserving customer analytics system through two key strategies.First,we deploy a deep learning framework using YOLOv9s,trained on the RCA-TVGender dataset.Cameras are positioned perpendicular to observation areas to reduce facial visibility while maintaining accurate gender classification.Second,we apply AES-128 encryption to customer position data,ensuring secure access and regulatory compliance.Our system achieved overall performance,with 81.5%mAP@50,77.7%precision,and 75.7%recall.Moreover,a 90-min observational study confirmed the system’s ability to generate privacy-protected heatmaps revealing distinct behavioral patterns between male and female customers.For instance,women spent more time in certain areas and showed interest in different products.These results confirm the system’s effectiveness in enabling personalized layout and marketing strategies without compromising privacy.
文摘Latest digital advancements have intensified the necessity for adaptive,data-driven and socially-centered learning ecosystems.This paper presents the formulation of a cross-platform,innovative,gamified and personalized Learning Ecosystem,which integrates 3D/VR environments,as well as machine learning algorithms,and business intelligence frameworks to enhance learner-centered education and inferenced decision-making.This Learning System makes use of immersive,analytically assessed virtual learning spaces,therefore facilitating real-time monitoring of not just learning performance,but also overall engagement and behavioral patterns,via a comprehensive set of sustainability-oriented ESG-aligned Key Performance Indicators(KPIs).Machine learning models support predictive analysis,personalized feedback,and hybrid recommendation mechanisms,whilst dedicated dashboards translate complex educational data into actionable insights for all Use Cases of the System(Educational Institutions,Educators and Learners).Additionally,the presented Learning System introduces a structured Mentoring and Consulting Subsystem,thence reinforcing human-centered guidance alongside automated intelligence.The Platform’s modular architecture and simulation-centered evaluation approach actively support personalized,and continuously optimized learning pathways.Thence,it exemplifies a mature,adaptive Learning Ecosystem,supporting immersive technologies,analytics,and pedagogical support,hence,contributing to contemporary digital learning innovation and sociotechnical transformation in education.
