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Acute amnesia during pregnancy due to bilateral fornix infarction: A case report 被引量:2
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作者 Min Jai Cho Dong-Ick Shin +1 位作者 Moon-Ku Han Kyu Sun Yum 《World Journal of Clinical Cases》 SCIE 2020年第19期4494-4498,共5页
BACKGROUND Stroke is an important cause of maternal morbidity and mortality during pregnancy and puerperium.Isolated amnesia is a rare clinical symptom caused by ischemic stroke during pregnancy.We present the first d... BACKGROUND Stroke is an important cause of maternal morbidity and mortality during pregnancy and puerperium.Isolated amnesia is a rare clinical symptom caused by ischemic stroke during pregnancy.We present the first documented case of acute amnesia during pregnancy due to bilateral fornix infarction.CASE SUMMARY A 32-year-old nullipara presented at 35 wk of gestation with acute amnesia and headache.Brain magnetic resonance imaging and angiography revealed acute infarction in the bilateral anterior fornix.There was no evidence of causative abnormality after extensive work-up,including for vascular abnormality,cardiac disease,coagulopathy,and pregnancy-related conditions.The patient was diagnosed with cryptogenic stroke.Aspirin was administered immediately,and the patient recovered fully without recurrence.CONCLUSION Acute isolated amnesia due to stroke is rare during pregnancy.Early diagnosis of stroke and immediate treatment prevent neurologic sequelae. 展开更多
关键词 FORNIX Brain amnesia Cerebral infarction PREGNANCY Stroke Case report
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Anti-Amnesic Activity of Vitex Negundo in Scopolamine Induced Amnesia in Rats 被引量:2
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作者 Abhinav Kanwal Jogender Mehla +3 位作者 Madhusudana Kuncha Vegi Ganga Modi Naidu Yogendra Kumar Gupta Ramakrishna Sistla 《Pharmacology & Pharmacy》 2010年第1期1-8,共8页
In the present study we investigated the anti-amnesic activity of Vitex negundo in scopolamine induced amnesia in rats. Wistar rats (180-200 g) were trained on active avoidance task. Each animal received session of 15... In the present study we investigated the anti-amnesic activity of Vitex negundo in scopolamine induced amnesia in rats. Wistar rats (180-200 g) were trained on active avoidance task. Each animal received session of 15 trials with inter trial duration of 15 s for 5 days. Scopolamine (3 mg/kg, i.p) was administered at different time periods on the basis of stages of memory i.e acquisition, consolidation and retention in different groups (n = 6). Effect of Vitex negundo extract was evaluated and compared to a standard drug, Donepezil. Significant (p 【0.05) increase in the avoidance response on the 5th session has been observed as compared to 1st session in control group. Scopolamine treatment significantly (p 【0.05) reduced the avoidance response compared to control. Extract treated groups shown significant (p 【0.05) increase in number of avoidance responses as compared to scopolamine treated groups. Increased oxidative stress in brain after scopolamine treatment, as observed by increase in MDA &amp;decrease in GSH &amp;SOD, was lowered in the groups treated with extracts. AChE activity was also improved after V. negundo treatment. Results of the study have shown that V. negundo treated groups decrease the phenomenon of amnesia by increasing learning of memory through antioxidant effect and decreasing AChE activity. 展开更多
关键词 VITEX Negundo amnesia Acetylcholinestrase SCOPOLAMINE Learning and Memory OXIDATIVE Stress
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Combating Historical Amnesia:The Memory-individual as the Living Memory in Marilynne Robinson’s Gilead 被引量:1
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作者 LU Ying-ru 《Journal of Literature and Art Studies》 2021年第11期873-877,共5页
In Marilynne Robinson's Gilead,the first John Ames is the memory-individual whose personal memory serves as the living memory to combat the collective historical amnesia of Iowa’s antislavery movement.For all his... In Marilynne Robinson's Gilead,the first John Ames is the memory-individual whose personal memory serves as the living memory to combat the collective historical amnesia of Iowa’s antislavery movement.For all his efforts,memory is framed by the present.Gilead has forgotten its abolitionist root and anti-racial discrimination tradition.The individual effort to resist collective historical amnesia fails.Through the first Ames’s failure,Robinson presents the politics of memory,particularly the struggle between individual memory and collective historical amnesia.The historical amnesia of abolitionism over Gilead is Robinson’s criticism of the present societal betrayal of the pursuit of racial equality as epitomized in the historical antislavery movement.Robinson’s memory writing in Gilead is also her literary endeavor to remember the forgotten history and to reflect upon the racial issue pervading present American society. 展开更多
关键词 Marilynne Robinson GILEAD Historical amnesia Memory-individual
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Effectiveness of lorazepam-assisted interviews in an adolescent with dissociative amnesia A case report
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作者 Yuna Seo Mi-Hee Shin +1 位作者 Sung-Gon Kim Ji-Hoon Kim 《Neural Regeneration Research》 SCIE CAS CSCD 2013年第2期186-190,共5页
To facilitate gathering information during a psychiatric interview, some psychiatrists advocate augmenting the interview using drugs. Rather than barbiturates, benzodiazepines have been used for drug-assisted intervie... To facilitate gathering information during a psychiatric interview, some psychiatrists advocate augmenting the interview using drugs. Rather than barbiturates, benzodiazepines have been used for drug-assisted interviews. Dissociative amnesia is one of the indications for these interviews. Herein, we present the case of a 15-year-old female who was diagnosed as having dissociative amnesia because of conflicts with her friends. She was administered a Iorazepam-assisted interview to aid recovery of her memories. In this case, a small dose of Iorazepam was sufficient to recover her memories without any adverse effects. 展开更多
关键词 neural regeneration clinical practice dissociative amnesia dissociative disorder dissociation drug-assisted interview amobarbital Iorazepam BENZODIAZEPINE ADOLESCENT memory loss emotional distress DISTRESS grant-supported paper NEUROREGENERATION
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Unexpected anterograde amnesia associated with Buscopan used as a predmedication for endocscopy
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作者 Hyuk Lee Hee Jung Son +2 位作者 Poong-Lyul Rhee Jae J Kim Jong Chul Rhee 《World Journal of Gastroenterology》 SCIE CAS CSCD 2007年第28期3895-3896,共2页
It has been known that peripheral adverse event is caused by peripheral antimuscarinic action, from hyoscine butylbromide (Buscopan; Boehringer Ingelheim, Germany) used as a premedication for endoscopy. However, sympt... It has been known that peripheral adverse event is caused by peripheral antimuscarinic action, from hyoscine butylbromide (Buscopan; Boehringer Ingelheim, Germany) used as a premedication for endoscopy. However, symptoms or signs associated with the central nervous system are rarely reported in the field of anesthesiology and peripartum labor. This central anticholinergic syndrome is likely caused by blockade of muscarinic cholinergic receptors in the central nervous system. There is no report on Buscopan-induced central anticholinergic syndrome in endoscopy room so far. Three middle-aged females unexpectedly suffered from anterograde amnesia after intramuscular injection of hyoscine butylbromide as an antispasmodic premedication for endoscopy at our endoscopy unit in the Health Promotion Center. 展开更多
关键词 ENDOSCOPY Hyoscine butylbromide Central anticholinergic syndrome amnesia
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Transient global amnesia after epiduroscopy in a failed back surgery syndrome patient: Case report
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作者 Leonardo Consoletti Antonella Cotoia +1 位作者 Gilda Cinnella Michele Dambrosio 《Health》 2013年第11期7-11,共5页
Epiduroscopy (EDS) allows diagnosis and treatment of spinal nerve root pathology by a fiberoptic device inserted percutaneously in the epidural space. Transient global amnesia syndrome (TGA) is defined by an abrupt on... Epiduroscopy (EDS) allows diagnosis and treatment of spinal nerve root pathology by a fiberoptic device inserted percutaneously in the epidural space. Transient global amnesia syndrome (TGA) is defined by an abrupt onset of an anterograde and retrograde amnesia that lasts up to 24 h, although mild subclinical neuropsychological deficits, with concomitant vegetative symptoms, can last for days after the episode. To our knowledge no cases of TGA in association with EDS have been recognized. We present a case of a 54-year-old man who was admitted for EDS, having experienced two times the failed surgery for spinal and left leg pain. During the EDS, 10 ml of non-ionic contrast media (CM) was injected to confirm the inside lesions. The epidural adhesions were gently broken down and drugs were injected around any inflamed nerve roots. Immediately after EDS, the patient experienced a TGA with loss of memory for the recent procedure and an impaired ability to retain new information. There were no signs of confusion or altered conscious level or seizure activities and neurological examination was normal. At 24 h a cranial computerized tomography (cCT) without CM showed “abnormal contrast enhancement at subarachnoid liquoral spaces levels”, then at 72 h cCT control was normal. The patient was discharged on the seventh day with perioperative lacunar amnesia persisting at this time. Herein, we sought a possible relationship between neurotoxic effect of CM and TGA in a patient emotionally stressed, even if the CM dose was given as a normal clinical range. 展开更多
关键词 INTRATHECAL Injection of Radiopaque CONTRAST EPIDUROSCOPY FAILED Back Surgery Syndrome Transient Global amnesia NONIONIC CONTRAST Media
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Case Study on Focal Retrograde Amnesia due to Limbic Encephalitis
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作者 Nobuhiro Takahashi Mimpei Kawamura +2 位作者 Naoki Tanihara Mamiko Sato Yasutaka Kobayashi 《World Journal of Neuroscience》 2020年第2期91-100,共10页
This case study addresses episodic memory impairment or focal retrograde amnesia related to limbic encephalitis. The patient in question was a right-handed man in his 60s who developed focal retrograde amnesia due to ... This case study addresses episodic memory impairment or focal retrograde amnesia related to limbic encephalitis. The patient in question was a right-handed man in his 60s who developed focal retrograde amnesia due to limbic encephalitis. An abnormal MRI signal was observed in the right medial temporal lobe. Immediately after the encephalitis onset, mental symptoms—including impaired consciousness, disorientation, hallucinations, and delusions—appeared;however, his condition improved with medical treatment. After transfer to a convalescent and rehabilitation hospital, various neuropsychological tests were conducted but no apparent functional decline was observed in intellectual function, attention, memorization, or retention. However, the patient exhibited impairments related to autobiographical memory and memory of events 4?-?5 years before the onset of limbic encephalitis. Based on these observations, the patient was considered to exhibit focal retrograde amnesia due to limbic encephalitis. Despite exhibiting retrograde amnesia, he had no difficulty in his daily life in the ward. Moreover, after discharge from hospital, smooth work reinstatement was possible. This case demonstrates that, even after exhibiting retrograde amnesia, if its duration is relatively short and physical function and other higher-order brain functions are sustained, social rehabilitation—including work reinstatement—is feasible. 展开更多
关键词 LIMBIC ENCEPHALITIS FOCAL Retrograde amnesia Medial Temporal LOBE Topographic DISORIENTATION Social Rehabilitation
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Lost in the Present: Anterograde Amnesia and Medical Decision Making Capacity
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作者 John McKelvie Christopher A. Pierce +2 位作者 Thomas M. Dunn Philippe Weintraub Robert M. House 《Open Journal of Medical Psychology》 2014年第1期54-59,共6页
Although there have been a limited number of case reports of human bilateral hippocampal injury, none of these have addressed the impact of such injuries on medical decision making capacity. The authors present a case... Although there have been a limited number of case reports of human bilateral hippocampal injury, none of these have addressed the impact of such injuries on medical decision making capacity. The authors present a case of an elderly man with discrete bilateral hippocampal injury. As a result of his injury, the patient was hopelessly “lost in the present” and only retained the basic cognitive functions necessary to have decision making capacity for a limited period of time. He was unable to appreciate the nature of his injury, the potential risks involved in his decisions, and the recommended course of treatment longer than a few minutes. The patient’s resultant neurocognitive deficits left him lacking medical decision making capacity, a likely outcome for patients with persistent anterograde amnesia. 展开更多
关键词 Bilateral HIPPOCAMPAL Injury ANTEROGRADE amnesia Capacity Medical Decision Making Capacity EPISODIC Memory PROSPECTIVE Brain
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Research on the Influencing Factors of Character Amnesia —— Based on the Empirical Analysis of College Students in Kaifeng City, He’nan Province
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作者 XINGYuhan 《外文科技期刊数据库(文摘版)教育科学》 2022年第5期171-175,共5页
It is becoming more and more common in modern life that people forget words when they write. Based on the Logistics model, this study conducts a systematic empirical analysis on the influencing factors and heterogenei... It is becoming more and more common in modern life that people forget words when they write. Based on the Logistics model, this study conducts a systematic empirical analysis on the influencing factors and heterogeneity of this phenomenon through a questionnaire survey of college students in Kaifeng City, He’nan Province. The results show that students professional differences, Chinese character use habits, environmental edification and attitude towards this phenomenon have an effect of 2.2%~5.4%. The higher the frequency of learning and output using electronic devices, the more likely it is that the phenomenon of character amnesia will appear. Moreover, this effect has both gender and grade heterogeneity. 展开更多
关键词 character amnesia Logistics model heterogeneity analysis
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Gentiana lutea extract ameliorates scopolamine-induced amnesia in mice via cholinergic modulation and inhibition of Aβ/p-tau protein accumulation
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作者 Tripathi Rashmi Sachdeva Monika Kumar Nitin 《Asian Pacific Journal of Tropical Biomedicine》 2025年第10期420-431,共12页
Objective:To investigate the potential of hydro-alcoholic extract of Gentiana lutea roots(GLE)in scopolamine-induced amnesia model in mice.Methods:The active chemical constituents were determined by GC-MS analysis.In ... Objective:To investigate the potential of hydro-alcoholic extract of Gentiana lutea roots(GLE)in scopolamine-induced amnesia model in mice.Methods:The active chemical constituents were determined by GC-MS analysis.In vitro antioxidant activity was performed by the DPPH free radical scavenging method.Ex vivo anti-acetylcholinesterase assay was conducted to investigate the effect on the cholinergic system.A scopolamine-induced memory impairment model was used.The levels of beta-amyloid(Aβ)and tau protein were measured.The behavioral studies were performed through Morris water maze and passive avoidance learning tests,followed by estimation of biochemical markers(GSH and MDA),immunohistochemistry,and histopathological studies on isolated brain tissues.Results:GLE exhibited DPPH free radical scavenging activity with an IC50 value of(76.68±2.28)μg/mL.GLE also manifested inhibitory effect on acetylcholinesterase[IC50(36.58±0.73)μg/mL]to upregulate the cholinergic system.GLE at 200 mg/kg and 400 mg/kg significantly restored the memory impairment induced by scopolamine.GLE at 200 mg/kg and 400 mg/kg significantly reduced brain oxidative stress(P<0.001).Immunohistochemistry investigation showed a significant reduction in Aβdeposition and p-tau protein expression in the GLE treatment groups(P<0.001).Administration of GLE effectively reduced scopolamine-induced neuronal damage in a dose-dependent manner.Conclusions:The study demonstrates that GLE ameliorates scopolamine-induced memory impairment by alleviating Aβ/p-tau protein accumulation and upregulation in the cholinergic system to improve cognitive dysfunction and behavioral problems. 展开更多
关键词 amnesia Beta amyloid Scopolamine Alzheimer’s disease Acetylcholine p-tau protein Acetylcholinesterase Gentiana lutea
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Contrast study on cognitive function with MRI and positron emission tomography imaging in transient global amnesia
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作者 贾建军 王鲁宁 +1 位作者 尹岭 汤洪川 《Chinese Medical Journal》 SCIE CAS CSCD 2002年第9期1321-1323,146,共3页
OBJECTIVE: To study cognitive function and cerebral metabolic changes in patients with transient global amnesia (TGA). METHODS: Three patients with TGA were given mini-mental state examination (MMSE), revised Wechsler... OBJECTIVE: To study cognitive function and cerebral metabolic changes in patients with transient global amnesia (TGA). METHODS: Three patients with TGA were given mini-mental state examination (MMSE), revised Wechsler memory scale (WMS-R) examination and magnetic resonance imaging (MRI) scans after they had been diagnosed as TGA. Using (18)F labelled deoxyglucose as tracer, patients were given a positron emission tomography (PET) examination at different periods during recovery. RESULTS: No obvious abnormality was found in MMSE and MRI scans in the three patients. However, WMS-R examination and cerebral PET imaging displayed cognitive dysfunction of varying degrees and low metabolism in local areas related to memory in 2 of 3 patients. CONCLUSIONS: In TGA patients, cognitive function and cerebral metabolic levels are closely correlated with duration of symptoms. It is necessary to stop the TGA attack as quickly as possible early time. 展开更多
关键词 COGNITION Magnetic Resonance Imaging Tomography Emission-Computed Aged amnesia Transient Global FEMALE Humans Male Middle Aged
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柔肝调神针刺法联合认知训练治疗肝郁血虚型帕金森病轻度认知障碍临床观察
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作者 彭天忠 朱满华 +1 位作者 占琦楠 黄学娣 《中国中医药现代远程教育》 2025年第18期137-140,共4页
目的观察柔肝调神针刺法联合认知训练治疗肝郁血虚型帕金森病轻度认知障碍(Parkinson’sdisease with mild cog-nitive impairment,PD-MCI)的临床效果。方法临床收集62例肝郁血虚型PD-MCI患者,随机分为观察组和对照组。观察组予以柔肝... 目的观察柔肝调神针刺法联合认知训练治疗肝郁血虚型帕金森病轻度认知障碍(Parkinson’sdisease with mild cog-nitive impairment,PD-MCI)的临床效果。方法临床收集62例肝郁血虚型PD-MCI患者,随机分为观察组和对照组。观察组予以柔肝调神针刺法联合认知训练治疗,对照组予以认知训练治疗。2组均采用简明精神状态检查表(MMSE)、蒙特利尔认知评估量表(MoCA)和帕金森病生活质量量表(PDQ-39)进行评价。结果治疗后,2组肝郁血虚型PD-MCI患者MMSE评分和MoCA评分均提高,PDQ-39评分均降低,且观察组各项评分均明显优于对照组(P<0.05)。结论柔肝调神针刺法联合认知训练治疗肝郁血虚型PD-MCI效果明显,能有效改善患者认知功能,提高患者生活质量,值得临床推广运用。 展开更多
关键词 健忘 帕金森病轻度认知障碍 柔肝调神针刺法 认知训练 中西医结合疗法
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从认知灵活性探讨长期负性情绪积累肝失疏泄致遗忘型轻度认知功能障碍的研究进展 被引量:2
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作者 秦中朋 詹向红 霍磊 《世界科学技术-中医药现代化》 北大核心 2025年第3期752-761,共10页
脑老化过速已成为亟待解决的社会问题和医学难题,其中遗忘型轻度认知功能障碍(Amnesia mild cognitive impairment,aMCI)因更易进展为阿尔茨海默病(Alzheimer’s disease,AD)而备受关注。国内外多项研究报道,执行功能减退是认知老化的... 脑老化过速已成为亟待解决的社会问题和医学难题,其中遗忘型轻度认知功能障碍(Amnesia mild cognitive impairment,aMCI)因更易进展为阿尔茨海默病(Alzheimer’s disease,AD)而备受关注。国内外多项研究报道,执行功能减退是认知老化的始动因子、关键损伤和敏感指标,且长期负性情绪积累肝失疏泄是罹患aMCI的重要危险因素,疏肝法可改善aMCI患者总体认知功能,但以上机制均有待进一步研究阐释。本文聚焦认知衰退早期敏感成分和执行功能核心成分之一的认知灵活性水平,总结梳理aMCI的发病机制、危险因素、敏感指标及认知神经科学研究事件相关电位和眼动技术,并重点探讨长期负性情绪积累肝失疏泄对aMCI和认知灵活性的影响及研究进展,以期为aMCI患者的情志病机干预和治疗提供参考和借鉴,为中医药防治认知功能衰退过速类疾病提供新视角、方法和思路。 展开更多
关键词 长期负性情绪积累 肝失疏泄 遗忘型轻度认知功能障碍 认知灵活性 疏肝法
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健忘病证与辨治考述
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作者 马东瑞 李煜 +1 位作者 薛昊 陈仁寿 《中华中医药杂志》 北大核心 2025年第9期4711-4716,共6页
健忘,亦称“喜忘”“善忘”等,主要指记忆力陡然下降,易于忘事。“健忘”一名首见于《脉经》,唐代孙思邈首先将其视作一种证候,北宋《太平圣惠方》将其视作独立疾病,病机、分证、方药遂于此齐备,流传至今。从古至今,医家对于健忘病位的... 健忘,亦称“喜忘”“善忘”等,主要指记忆力陡然下降,易于忘事。“健忘”一名首见于《脉经》,唐代孙思邈首先将其视作一种证候,北宋《太平圣惠方》将其视作独立疾病,病机、分证、方药遂于此齐备,流传至今。从古至今,医家对于健忘病位的认识经历了多次转移,于明末清初以后,逐渐落定在脑。横向对比健忘相关疾病,得出健忘重要病机为心脾两虚、痰浊扰心,心胆不足可能是健忘的另一个重要病机。健忘其他病机如心肾不交、瘀血停滞亦见。情志因素是导致健忘的重要病因,健忘的发病亦与年龄有一定关联。在健忘的论治上,应根据其临床表现治以补益心脾、交通心肾、理气活血。 展开更多
关键词 健忘 考证 辨证论治 文献研究
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生慧汤治疗失眠伴健忘作用机制的研究进展
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作者 黄熙芮 丁莉 +2 位作者 尹超 游秋云 张美娅 《时珍国医国药》 北大核心 2025年第17期3333-3339,共7页
失眠与健忘关系密切,二者以元气亏虚为发病基础,以肾精匮乏、心肾不交为共同的病因。生慧汤作为“培元补肾安神益智”法的代表方,具有培元健脑、交通心肾、安神益智的功效,主治健忘和失眠。为了使生慧汤更好地应用于失眠和健忘,现从失... 失眠与健忘关系密切,二者以元气亏虚为发病基础,以肾精匮乏、心肾不交为共同的病因。生慧汤作为“培元补肾安神益智”法的代表方,具有培元健脑、交通心肾、安神益智的功效,主治健忘和失眠。为了使生慧汤更好地应用于失眠和健忘,现从失眠伴健忘病因病机、生慧汤方解、临床应用与疗效评估和作用机制研究四个方面,对其进行总结,为防治失眠与健忘提供理论基础和临床指导意义。 展开更多
关键词 失眠 健忘 生慧汤 作用机制
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Does consciousness overflow cognitive access?Novel insights from the new phenomenon of attribute amnesia 被引量:2
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作者 Yingtao Fu Wenchen Yan +1 位作者 Mowei Shen Hui Chen 《Science China(Life Sciences)》 SCIE CAS CSCD 2021年第6期847-860,共14页
The moment we open our eyes,we experience a rich and detailed visual world,but the amount of information available to report is rather limited.This dissociation relates to a major debate regarding the nature of visual... The moment we open our eyes,we experience a rich and detailed visual world,but the amount of information available to report is rather limited.This dissociation relates to a major debate regarding the nature of visual consciousness.The overflow argument suggests that our conscious experience is quite rich and far beyond what can be reported,standing in sharp contrast to the nooverflow argument that visual consciousness is severely impoverished and limited to what can be reported.In this paper,we systematically reviewed existing evidence in favor of the overflow argument,including studies of several variations of the iconic memory paradigm and the divided attention paradigm,as well as studies of neural correlates of consciousness.Simultaneously,we expounded some critical objections and alternative interpretations to such evidence,as well as some opposing evidence.Finally,we introduced a series of our recent studies based on a striking phenomenon of attribute amnesia,which we believe could provide new insight into the overflow view of visual consciousness. 展开更多
关键词 phenomenal/access consciousness attribute amnesia attention working memory
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颈内静脉回流障碍对神经系统疾病的影响
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作者 黄浩淇 徐穗莲 +2 位作者 胡波 杨苗娟(综述) 何奕涛(审校) 《中风与神经疾病杂志》 2025年第4期370-374,共5页
颈内静脉回流障碍可广泛影响颅内血流动力学,目前研究发现颈内静脉回流障碍对多种神经系统疾病具有影响作用。本研究就颈内静脉回流障碍与短暂性全面性遗忘症、短暂性单眼失明、脑白质病变、认知功能障碍、帕金森病、原发性颅内高压、... 颈内静脉回流障碍可广泛影响颅内血流动力学,目前研究发现颈内静脉回流障碍对多种神经系统疾病具有影响作用。本研究就颈内静脉回流障碍与短暂性全面性遗忘症、短暂性单眼失明、脑白质病变、认知功能障碍、帕金森病、原发性颅内高压、多发性硬化以及一些非特异症状等的相关性进行综述,以拓展与颈内静脉回流障碍相关的神经系统疾病的临床诊疗思路。 展开更多
关键词 颈内静脉回流障碍 短暂性全面遗忘症 脑白质病变 认知功能障碍 短暂性单眼失明 帕金森病 原发性颅内高压 多发性硬化
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宫腔镜子宫内膜息肉切术椎管内麻醉与静脉复合麻醉对患者生命体征、血流动力学和顺行性遗忘的影响 被引量:1
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作者 孙盼盼 任传将 李利敏 《中国计划生育学杂志》 2025年第3期596-601,共6页
目的:考察并比较椎管内麻醉和静脉复合麻醉在宫腔镜子宫内膜息肉切术对患者生命体征、血流动力学和顺行性遗忘的影响。方法:纳入2021年1月-2023年12月本院收治的接受宫腔镜子宫内膜息肉切术患者130例,随机分为对照组(椎管内麻醉)和观察... 目的:考察并比较椎管内麻醉和静脉复合麻醉在宫腔镜子宫内膜息肉切术对患者生命体征、血流动力学和顺行性遗忘的影响。方法:纳入2021年1月-2023年12月本院收治的接受宫腔镜子宫内膜息肉切术患者130例,随机分为对照组(椎管内麻醉)和观察组(静脉复合麻醉)各65例。记录两组麻醉时间、失血量、输血、手术时间、术后下床活动时间,插管前或麻醉开始前(T1)、插管后或注药后3min(T2)、切皮后即刻(T3)、手术结束时(T4)生命体征指标每搏输出量(SV)、左心室射血分数(EF)和心输出量(CO),围术期血流动力学血氧饱和度(SpO_(2))、心率(HR)、平均动脉压(MAP)、顺行性遗忘、临床疗效和不良反应。结果:两组失血量、输血情况无差异(P>0.05),观察组麻醉时间、失血量、输血、手术时间均少于对照组,术后下床活动时间早于对照组(P<0.05)。T1,两组SV、EF、CO、SpO_(2)、HR、MAP无差异(P>0.05),T2~T4两组SV、EF、CO、SpO_(2)、HR、MAP均比T1不同程度降低但观察组变化幅度小于对照组(均P<0.05),观察组完全遗忘占比(93.9%)高于对照组(4.6%)(P<0.05)。两组术后总有效率、总不良反应均无差异(P>0.05)。结论:椎管内麻醉和静脉复合麻醉均可用于宫腔镜子宫内膜息肉切术,两者的有效性和安全性相当,但椎管内麻醉对患者的顺行性遗忘影响较小,静脉复合麻醉有助于稳定患者生命体征、血流动力学。 展开更多
关键词 宫腔镜子宫内膜息肉切术 椎管内麻醉 静脉复合麻醉 生命体征 血流动力学 顺行性遗忘 不良反应
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齐向华教授四诊合参辨治精神萎靡状态下健忘经验
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作者 王子玥 齐向华 滕晶 《中国中医药现代远程教育》 2025年第18期88-91,共4页
健忘是一种临床较为常见的中医病证,以近事遗忘、生活能力尚好为主要表现。此病以中老年人较为多见,严重影响其生活质量。精神萎靡状态既可作为疾病发生的原发病机,也可作为继发因素导致健忘等躯体化症状。从精神萎靡状态辨析健忘的病... 健忘是一种临床较为常见的中医病证,以近事遗忘、生活能力尚好为主要表现。此病以中老年人较为多见,严重影响其生活质量。精神萎靡状态既可作为疾病发生的原发病机,也可作为继发因素导致健忘等躯体化症状。从精神萎靡状态辨析健忘的病因病机,通过中医四诊有效辨识并基于“形神合一”理论综合辨治,可以达到身心共愈、形神俱佳的效果。 展开更多
关键词 健忘 精神萎靡状态 四诊合参 辨证论治 名医经验
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基于数据挖掘探究中成药治疗健忘用药规律
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作者 李京世 李小阳 +1 位作者 孙华君 雷蕾 《中国中医药图书情报杂志》 2025年第5期28-34,共7页
目的 探究中成药治疗健忘用药特点及组方规律,为临床治疗用药及中药新药研发提供参考。方法 在中医药数据挖掘系统中成药数据库检索治疗健忘相关数据,采用Excel2019、KNIME5.2.5、Cytoscape3.10.2、SPSS Statistics 25.0软件进行频次统... 目的 探究中成药治疗健忘用药特点及组方规律,为临床治疗用药及中药新药研发提供参考。方法 在中医药数据挖掘系统中成药数据库检索治疗健忘相关数据,采用Excel2019、KNIME5.2.5、Cytoscape3.10.2、SPSS Statistics 25.0软件进行频次统计、关联规则分析、聚类分析及可视化。结果 纳入中成药处方1 862首,涵盖14种剂型、519种主治、169种功效。涉及中药305味,常用药物为五味子、茯苓、当归,药性以温性为主,药味以甘味为主,主归肾经,功效以补气、补血为主,含有药食同源中药57种。中药-证候关联分析发现,当归、茯苓、枸杞子与气血两虚共现频次最高。得到关联规则27条,聚类分析归为3类。结论 中成药治疗健忘以补虚为治则,以补肾填精、健脾补益气血、宁心安神为用药特点,可为临床治疗用药及中药新药研发提供参考。 展开更多
关键词 健忘 轻度认知障碍 中成药 数据挖掘 用药规律 关联规则 聚类分析
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