In this paper we proposed an AMH Supply Chain model to obtain optimal solutions for Two-, Three- and Four-Stage for deterministic models. Besides deriving its algebraic solutions, a simple searching method is successf...In this paper we proposed an AMH Supply Chain model to obtain optimal solutions for Two-, Three- and Four-Stage for deterministic models. Besides deriving its algebraic solutions, a simple searching method is successfully applied in obtaining optimal total costs and its integer multipliers. Our model has shown promising results in comparison to Equal Cycle Time and other existing ones. The tests focused on obtaining optimal total annual costs and other related details of Two-, Three- and Four-Stage for deterministic models. The results are run under Visual Basic Programming platform using Intel? CoreTM2 Duo T6500 Processor.展开更多
目的:观察妇科养荣胶囊(Fu Ke Yang Rong capsule,FKYRC)对卵巢损伤小鼠卵巢储备功能和生育力的保护作用。方法:通过成年雌性小鼠一次性腹腔注射120 mg/kg环磷酰胺和10 mg/kg白消安建立卵巢损伤小鼠模型,于造模前7 d至造模后60 d每日对...目的:观察妇科养荣胶囊(Fu Ke Yang Rong capsule,FKYRC)对卵巢损伤小鼠卵巢储备功能和生育力的保护作用。方法:通过成年雌性小鼠一次性腹腔注射120 mg/kg环磷酰胺和10 mg/kg白消安建立卵巢损伤小鼠模型,于造模前7 d至造模后60 d每日对卵巢损伤小鼠用高、中、低剂量(6 g/kg、4 g/kg和2 g/kg)FKYRC(H组、M组、L组)连续灌胃给药;同时,于造模前7 d一次性皮下注射给予Gn RHa(38 mg/kg)作为阳性对照组(Gn RHa组),用生理盐水(0.2 m L/d)代替FKYRC连续灌胃作为卵巢损伤对照组(模型组),另设正常对照组:非卵巢损伤正常小鼠腹腔注射给予等体积DMSO(NC组)。分别于造模后30 d和60 d取材,计数卵巢组织中各级卵泡数量,检测血清E2、FSH、抑制素B(INHB)和抗苗勒氏管激素(AMH)水平,检测卵巢组织中翼状螺旋/叉头转录因子2(FOXL2)和AMH蛋白的表达水平。并观察造模60 d后各组妊娠率和窝仔数。结果:各给药组和模型组小鼠血清E2低于NC组(P<0.05),但FSH水平组间无统计学差异(P>0.05)。造模各组卵泡数明显低于NC组(P<0.05),且H组和Gn RHa组造模后60 d时卵巢组织中窦前卵泡与窦卵泡数较高,但各干预组与模型组比较无统计学差异(P>0.05)。模型组小鼠卵巢组织中FOXL2和AMH蛋白表达水平显著低于各FKYRC干预组(P<0.05),H组的妊娠率(80.00%)显著高于模型组(36.36%)(P<0.05)。结论:连续FKYRC(6 g/kg)给药60 d后可明显改善烷化剂所致卵巢损伤小鼠的卵巢储备功能和生育能力,其机制可能与上调颗粒细胞中FOXL2和AMH的表达水平相关。展开更多
Array是TFT-LCD制造过程中最关键的工艺,其中央搬送系统性能的优劣直接影响LCD产品的成本。针对Array中央搬送系统的特点,以平均等待搬运时间和"运输成本"最小化为目标,建立了问题的数学模型,并提出了DRWTTC(Dispatching Rule...Array是TFT-LCD制造过程中最关键的工艺,其中央搬送系统性能的优劣直接影响LCD产品的成本。针对Array中央搬送系统的特点,以平均等待搬运时间和"运输成本"最小化为目标,建立了问题的数学模型,并提出了DRWTTC(Dispatching Rule for Waiting Time and Transport Cost)算法对问题进行求解。通过仿真实例,验证了该算法在平均等待时间、3σ搬运时间及搬运效率等搬运系统性能方面优于现有生产线搬运系统广泛运用的FIFS及LWT等策略。展开更多
文摘In this paper we proposed an AMH Supply Chain model to obtain optimal solutions for Two-, Three- and Four-Stage for deterministic models. Besides deriving its algebraic solutions, a simple searching method is successfully applied in obtaining optimal total costs and its integer multipliers. Our model has shown promising results in comparison to Equal Cycle Time and other existing ones. The tests focused on obtaining optimal total annual costs and other related details of Two-, Three- and Four-Stage for deterministic models. The results are run under Visual Basic Programming platform using Intel? CoreTM2 Duo T6500 Processor.
文摘Array是TFT-LCD制造过程中最关键的工艺,其中央搬送系统性能的优劣直接影响LCD产品的成本。针对Array中央搬送系统的特点,以平均等待搬运时间和"运输成本"最小化为目标,建立了问题的数学模型,并提出了DRWTTC(Dispatching Rule for Waiting Time and Transport Cost)算法对问题进行求解。通过仿真实例,验证了该算法在平均等待时间、3σ搬运时间及搬运效率等搬运系统性能方面优于现有生产线搬运系统广泛运用的FIFS及LWT等策略。
