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Solar-Powered Aerobics Training Robot with Adaptive Energy Management for Improved Environmental Sustainability
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作者 Bevl Naidu Krishna Babu Sambaru +3 位作者 Guru Prasad Pasumarthi Romala Vijaya Srinivas K.Srinivasa Krishna V.Purna Kumari Pechetty 《Journal of Environmental & Earth Sciences》 2025年第6期482-496,共15页
With the rapid advancement of robotics and Artificial Intelligence(AI),aerobics training companion robots now support eco-friendly fitness by reducing reliance on nonrenewable energy.This study presents a solar-powere... With the rapid advancement of robotics and Artificial Intelligence(AI),aerobics training companion robots now support eco-friendly fitness by reducing reliance on nonrenewable energy.This study presents a solar-powered aerobics training robot featuring an adaptive energy management system designed for sustainability and efficiency.The robot integrates machine vision with an enhanced Dynamic Cheetah Optimizer and Bayesian Neural Network(DynCO-BNN)to enable precise exercise monitoring and real-time feedback.Solar tracking technology ensures optimal energy absorption,while a microcontroller-based regulator manages power distribution and robotic movement.Dual-battery switching ensures uninterrupted operation,aided by light and I/V sensors for energy optimization.Using the INSIGHT-LME IMU dataset,which includes motion data from 76 individuals performing Local Muscular Endurance(LME)exercises,the system detects activities,counts repetitions,and recognizes human movements.To minimize energy use during data processing,Min-Max normalization and two-dimensional Discrete Fourier Transform(2D-DFT)are applied,boosting computational efficiency.The robot accurately identifies upper and lower limb movements,delivering effective exercise guidance.The DynCO-BNN model achieved a high tracking accuracy of 96.8%.Results confirm improved solar utilization,ecological sustainability,and reduced dependence on fossil fuels—positioning the robot as a smart,energy-efficient solution for next-generation fitness technology. 展开更多
关键词 aerobics Training Robot Energy Power Supply Control Dynamic Cheetah Optimizer(DynCO) Bayesian Neural Network(BNN) Motion Recognition
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Study of Aerobics Effects on Female College Students' Health
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作者 Xinli Xing 《International Journal of Technology Management》 2013年第12期95-97,共3页
Aerobics includes gymnastics, music, dance and aesthetics, using specialized equipment by hand and holding light equipment to achieve fitness and operation of exercises, it is a bodybuilding methods centering for the ... Aerobics includes gymnastics, music, dance and aesthetics, using specialized equipment by hand and holding light equipment to achieve fitness and operation of exercises, it is a bodybuilding methods centering for the purpose of emerging entertainment and ornamental sports, and it is also a strong public artistic gymnastics. It is with superb skill, charming and colorful parade of action, posture which is coordinated with the music to demonstrate the extraordinary artistic charm, thus attracting more and more students to participate in. Because it is different from traditional hand gymnastic exercises, and does not have too high demands for space and equipment. Practicing it just needs fast-paced and lively musical accompaniment, and dynamic movements can make people feel good, so it wins the majority of young people, especially girls. Calisthenics is as one of the means to work out for students; in particular, it develops a lifelong habit of physical exercise and plays an important role for college girls' lifelong fitness awareness. The topic is studying female college students on aerobics body shape, function, quality and impact of mental health to promote the development of physical education reform. 展开更多
关键词 aerobics College Students HEALTH FITNESS
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Study on the Points Needing Attention in Aerobics Training of Junior College Students
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作者 Dan MIAO 《International Journal of Technology Management》 2013年第6期53-55,共3页
With the continuously increasing competition in the modern society, the learning pressure of students is getting greater and greater and many students are in shortage of reasonable time to take physical exercises so t... With the continuously increasing competition in the modern society, the learning pressure of students is getting greater and greater and many students are in shortage of reasonable time to take physical exercises so that they are in a state of sub-health for a long time. Aerobics, as a combination of music and sports, has been more and more popular among teachers and students. However, in aerobics training, the injuries to the physical bodies of students will be caused due to the improper training methods. Therefore, in this paper, the points needing attention in aerobics training is studied, and then scientific aerobics training methods are proposed. 展开更多
关键词 Junior College Students aerobics INJURIES Points Needing Attention
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Study on the Research and Application of Network Teaching Courseware in Aerobics in Colleges and Universities
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作者 Xiangxin Meng Huanxiang Ding +1 位作者 Yongjun Zhao Xueqin Zhuang 《International English Education Research》 2014年第11期41-45,共5页
Aerobics teaching in colleges and universities is the most important part of higher education, and the important means to carry out quality-oriented education and cultivate all-round developed talents. The reform of a... Aerobics teaching in colleges and universities is the most important part of higher education, and the important means to carry out quality-oriented education and cultivate all-round developed talents. The reform of aerobics teaching in colleges and universities should be geared to the demands of the times, and explore new innovation and continual development. In this paper, using the research methods of documentation, courseware development, teaching experiment and mathematical statistics, we study on the making and application of college aerobics network teaching courseware. It is revealed that, with the combination of modem network technology and college aerobics teaching, the resulted college aerobics network teaching courseware is the important media to not only upgrades college aerobics teaching quality, but also help develop students' habits of doing physical exercise, and promote physical health. Therefore, this is meaningful and practical in promoting the education of college students in physical quality development. 展开更多
关键词 Colleges and Universities aerobics the Network Teaching Courseware Prepare Test Application
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The influence that aerobics have on mental health of college students
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作者 Xinli Xing 《International Journal of Technology Management》 2013年第11期93-95,共3页
Aerobics become an indispensable item in college physical education class. The article will talk about the influence of aerobics on mental health of college students aiming at the fact that mass aerobics haven' t dev... Aerobics become an indispensable item in college physical education class. The article will talk about the influence of aerobics on mental health of college students aiming at the fact that mass aerobics haven' t developed very well. Aerobics expand the traditional pattern of school physical education, in addition to improve and animate sports classroom atmosphere; students can be fully met the physical and mental demand, so as students can be guided to actively participate in physical exercise, making further promotion of students' body and function development; students' physical fitness involving coordination, softness, power and endurance can also be fully developed. Students can develop good body posture, shape their physical beauty and performance of actions, cultivate sentiments and further demonstrate the beauty and health of themselves. 展开更多
关键词 aerobics mental health college students
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Research on Remote Aerobics Network Learning System based on B/S
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作者 Chao Fan 《International Journal of Technology Management》 2013年第1期14-16,共3页
through the design of teaching aerobics web-based course and application practice, the instructional design process based on B/ S learning are analyzed, and discusses several key problems in the design and teaching. T... through the design of teaching aerobics web-based course and application practice, the instructional design process based on B/ S learning are analyzed, and discusses several key problems in the design and teaching. This paper presents the resource based learning aerobics teaching design network course should adapt to the application mode of network teaching and traditional classroom combination; that will provide teaching demonstration, teaching contents for students as well as the function of self testing evaluation and provide the job management, teacher online Q & A, database and knowledge base construction, greatly improving the "aerobics" teaching efficiency. 展开更多
关键词 CAI B/S structure aerobics
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Research on the Infiltration of Humanistic Quality Education in College Aerobics Teaching
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作者 LI Dong 《外文科技期刊数据库(文摘版)教育科学》 2021年第8期039-041,共5页
At present, due to the continuous development and reform of quality education in our country, more and more fitness programs are appearing in colleges and universities. Nowadays, many students choose to do aerobic exe... At present, due to the continuous development and reform of quality education in our country, more and more fitness programs are appearing in colleges and universities. Nowadays, many students choose to do aerobic exercise. Aerobics teaching requires students to have a high degree of flexibility and balance, in order to help students shape a good figure. This paper first analyzes the importance of humanistic education in college aerobics teaching, then analyzes the challenges faced by college aerobics teaching, and finally puts forward the strategy of introducing "quality humanistic education" into college aerobics teaching for reference. 展开更多
关键词 UNIVERSITIES aerobics teaching humanistic quality education mode analysis
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Research on Teaching Reform of Aerobics in Colleges and Universities Based on Flipped Classroom
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作者 XIAO Tingting 《外文科技期刊数据库(文摘版)教育科学》 2021年第8期108-110,共5页
With the development of the times, benefiting from the progress of science and technology, education and teaching are constantly innovating and progressing. Aerobics teaching in colleges and universities is an importa... With the development of the times, benefiting from the progress of science and technology, education and teaching are constantly innovating and progressing. Aerobics teaching in colleges and universities is an important part of college education. Aerobics helps to shape students' physique and exercise students' will. It is of great value and significance to the growth and development of college students. The integrated application of flipped classroom in college aerobics teaching is not only a bold practice, but also a major breakthrough in education. This paper analyzes and discusses the integrated application of flipped classroom in college aerobics teaching, hoping to bring some help to aerobics teachers engaged in college education. 展开更多
关键词 flipped classroom college aerobics reform and practice
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The Effects of the Aerobics Exercise Program on the Cardiopulmoner Capacity and Disease Symptoms of the Patients with Primary Fibromialgia Syndrome
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作者 Berat Meryem Alkan Sumru Ozel +1 位作者 Serap Tomruk Sütbeyaz Canan Culha 《Open Journal of Rheumatology and Autoimmune Diseases》 2013年第4期202-208,共7页
Backgrounds: To observe the effects of aerobic exercise program on the illness symptoms and cardiopulmonary capacity of the patients with primary Fibromyalgia Syndrome (FMS) and to find out whether there is a differen... Backgrounds: To observe the effects of aerobic exercise program on the illness symptoms and cardiopulmonary capacity of the patients with primary Fibromyalgia Syndrome (FMS) and to find out whether there is a difference or not in terms of cardiovascular capacity among the patients with primary FMS and sedentary healthy people. Materials and Methods: The study has been done on 20 female patients with primary FMS. Before the study and after a 6-week controlled aerobic exercise program, a cardiopulmonary exercise test has been applied on all cases. The symptoms, psychological state and life quality of the cases have been evaluated before and after the exercise program. The first cardiopulmonary results of the cases with FMS have been compared with a control group of 15 sedentary healthy. Results: When the patient and control groups are compared, although maksimal oxygen uptake (VO2 max) was lower in the patient group, this was not a significant difference. VO2 max showing the aerobic condition after the exercise increased significantly in the patients. Conclusions: Aerobic exercise programs lasting six to eight weeks are quite effective for the patients with FMS. There is not any limitation in the increase of the cardiopulmonary capacity of the patients after the exercise program. 展开更多
关键词 Aerobic Exercise Cardiopulmonary Capacity Primary Fibromyalgia Syndrome
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Visible Light-Promoted Aerobic Oxo-azidation of Alkenyl Silanes
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作者 Tan Yan Ying Jiale +1 位作者 Yu Bing Lu Zhan 《有机化学》 北大核心 2025年第5期1684-1690,共7页
A visible-light-enabled method for the synthesis ofα-azidoketones has been developed via oxo-azidation of alkenyl silanes with trimethylsilylazide and molecular oxygen under mild conditions.The reaction could be carr... A visible-light-enabled method for the synthesis ofα-azidoketones has been developed via oxo-azidation of alkenyl silanes with trimethylsilylazide and molecular oxygen under mild conditions.The reaction could be carried out in gram scale.Various radical sources,including trifluoromethyl radical,thiocyanate radical,bromide radical,chlorine radical could partici-pate effectively instead of azide radical in the reaction. 展开更多
关键词 visible light catalysis aerobic oxidation alkenyl silanes organic azides
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Feasibility and effects of remotely supervised aerobic training and resistance training in older adults with mild cognitive impairment:a pilot three-arm randomised controlled trial
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作者 Xiuxiu Huang Shifang Zhang +9 位作者 Xiaoyan Zhao Xinrui Li Fulian Bao Yue Lan Yuyao Zhang Ran An Bei Li Fang Yu Yongan Sun Qiaoqin Wan 《General Psychiatry》 2025年第2期123-133,共11页
Background Evidence on the effects of different exercise interventions on cognitive function is insufficient.Aims To evaluate the feasibility and effects of remotely supervised aerobic exercise(AE)and resistance exerc... Background Evidence on the effects of different exercise interventions on cognitive function is insufficient.Aims To evaluate the feasibility and effects of remotely supervised aerobic exercise(AE)and resistance exercise(RE)interventions in older adults with mild cognitive impairment(MCI).Methods This study is a 6-month pilot three-arm randomised controlled trial.Eligible participants(n=108)were recruited and randomised to the AE group,RE group or control(CON)group with a 1:1:1 ratio.Interventions were delivered at home with remote supervision.We evaluated participants’global cognition,memory,executive function,attention,physical activity levels,physical performance and muscle strength of limbs at baseline,3 months(T1)and 6 months(T2)after randomisation.A linear mixed-effects model was adopted for data analyses after controlling for covariates.Tukey’s method was used for adjusting for multiple comparisons.Sensitivity analyses were performed after excluding individuals with low compliance rates.Results 15(13.89%)participants dropped out.The median compliance rates in the AE group and RE group were 67.31%and 93.27%,respectively.After adjusting for covariates,the scores of the Alzheimer’s Disease Assessment Scale-Cognitive subscale in the AE group decreased by 2.04(95%confidence interval(CI)−3.41 to−0.67,t=−2.94,p=0.004)and 1.53(95%CI−2.88 to−0.17,t=−2.22,p=0.028)points more than those in the CON group at T1 and T2,respectively.The effects of AE were still significant at T1(estimate=−1.70,95%CI−3.20 to−0.21,t=−2.69,p=0.021),but lost statistical significance at T2 after adjusting for multiple comparisons.As for executive function,the Stroop time interference in the RE group decreased by 11.76 s(95%CI−21.62 to−1.90,t=−2.81,p=0.015)more than that in the AE group at T2 after Tukey’s adjustment.No other significant effects on cognitive functions were found.Conclusions Both remotely supervised AE and RE programmes are feasible in older adults with MCI.AE has positive effects on global cognition,and RE improves executive function. 展开更多
关键词 cognitive function resistance exercise re interventions exercise interventions remotely supervised aerobic exercise ae aerobic training remote supervision randomised controlled mild cognitive
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Impacts of High-Intensity Interval Training on Aerobic Capacity, Walking and Balance Function in Stroke Survivors
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作者 Xueli XIANG 《Medicinal Plant》 2025年第5期55-59,66,共6页
[Objectives]To synthesize evidence on HIIT versus moderate-intensity continuous training(MICT)or routine rehabilitation in stroke survivors.[Methods]We systematically searched 8 databases(PubMed,EMBASE,CENTRAL,Web of ... [Objectives]To synthesize evidence on HIIT versus moderate-intensity continuous training(MICT)or routine rehabilitation in stroke survivors.[Methods]We systematically searched 8 databases(PubMed,EMBASE,CENTRAL,Web of Science,SPORTSDiscus,PsycINFO,SCOPUS,CINAHL)up to May 2025.Seventeen randomized controlled trials(RCTs;total n=1142)met inclusion criteria:adults with stroke,device-based HIIT(≥70%HRR/VO 2peak),and outcomes assessing VO 2peak,6-min walk distance(6MWD),or Berg Balance Scale(BBS).Methodological quality was evaluated using the PEDro scale.Pooled effect sizes(Hedges'g)were calculated via random-effects models,with heterogeneity quantified by I^(2).[Results]HIIT significantly improved peak oxygen uptake(VO 2peak)versus controls(g=0.59,95%CI:0.44-0.75,p<0.001;I^(2)=16.29%).Low heterogeneity and symmetrical funnel plots supported robustness.HIIT also enhanced walking endurance(6MWD:g=0.32,95%CI:0.16-0.48,p<0.01;I^(2)=30%).In contrast,no significant benefit was observed for balance function(BBS:g=0.07,95%CI:-0.13-0.26,p=0.50;I^(2)=0%).[Conclusions]HIIT is a safe and highly effective intervention for enhancing aerobic capacity and walking function post-stroke.Its benefits are maximized at higher intensities and longer durations but do not extend to balance improvement.Integrating HIIT into stroke rehabilitation protocols is strongly recommended to promote functional independence. 展开更多
关键词 High-Intensity Interval Training (HIIT) AEROBIC capacity WALKING BALANCE Stroke SURVIVORS
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Research Advances in Fertilizer Production Technologies Utilizing Solid Waste Resources
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作者 Xiaofang ZHENG Yanjun GUO +4 位作者 Zitao WU Sen WANG Yue ZHANG Ying XIAO Yunxuan OUYANG 《Asian Agricultural Research》 2025年第11期29-35,40,共8页
The conversion of waste resources into fertilizer represents a crucial strategy for optimizing waste utilization and attaining"carbon peak and neutrality"objectives.This approach not only effectively mitigat... The conversion of waste resources into fertilizer represents a crucial strategy for optimizing waste utilization and attaining"carbon peak and neutrality"objectives.This approach not only effectively mitigates greenhouse gas emissions but also enhances the organic matter content in soil,thereby supporting the advancement of sustainable agriculture.Currently,the principal fertilizer production technologies utilizing solid waste resources encompass hydrothermal fertilizer production,aerobic fermentation,wrapping fertilizer production,micro-storage fertilizer production,and biochemical rapid decomposition.This paper examines the applicability and limitations of these technologies in practical contexts,and anticipates their developmental trends and future prospects.It aims to offer practical guidance and constructive support for the resource utilization of solid waste and the sustainable development of related industries. 展开更多
关键词 Solid WASTE utilization WASTE FERTILIZER production technology Hydrothermal CARBONIZATION AEROBIC fermentation Current application RESEARCH advance
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Effects of short-and long-term exercise training on cancer cells in vitro:Insights into the mechanistic associations
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作者 Francesco Bettariga Dennis R.Taaffe +1 位作者 Daniel A.Galvão Robert U.Newton 《Journal of Sport and Health Science》 2025年第1期73-83,共11页
Exercise is a therapeutic approach in cancer treatment,providing several benefits.Moreover,exercise is associated with a reduced risk for developing a range of cancers and for their recurrence,as well as with improvin... Exercise is a therapeutic approach in cancer treatment,providing several benefits.Moreover,exercise is associated with a reduced risk for developing a range of cancers and for their recurrence,as well as with improving survival,even though the underlying mechanisms remain unclear.Preclinical and clinical evidence shows that the acute effects of a single exercise session can suppress the growth of various cancer cell lines in vitro.This suppression is potentially due to altered concentrations of hormones(e.g.,insulin)and cytokines(e.g.,tumor necrosis factor alpha and interleukin 6)after exercise.These factors,known to be involved in tumorigenesis,may explain why exercise is associated with reduced cancer incidence,recurrence,and mortality.However,the effects of short-(<8 weeks)and long-term(≥8 weeks)exercise programs on cancer cells have been reported with mixed results.Although more research is needed,it appears that interventions incorporating both exercise and diet seem to have greater inhibitory effects on cancer cell growth in both apparently healthy subjects as well as in cancer patients.Although speculative,these suppressive effects on cancer cells may be driven by changes in body weight and composition as well as by a reduction in low-grade inflammation often associated with sedentary behavior,low muscle mass,and excess fat mass in cancer patients.Taken together,such interventions could alter the systemic levels of suppressive circulating factors,leading to a less favorable environment for tumorigenesis.While regular exercise and a healthy diet may establish a more cancer-suppressive environment,each acute bout of exercise provides a further“dose”of anticancer medicine.Therefore,integrating regular exercise could potentially play a significant role in cancer management,highlighting the need for future investigations in this promising area of research. 展开更多
关键词 Resistance training Aerobic training CYTOKINES HORMONES Cancer cells
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Aerobic exercise alleviates statin-induced PCSK9 upregulation by increasing epoxyeicosatrienoic acid levels through the FoxO3a-Sirt6 axis
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作者 Jiahui Hu Hao Lei +4 位作者 Jingyuan Chen Leiling Liu Yajun Gui Kaijun Sun Danyan Xu 《Journal of Sport and Health Science》 2025年第2期91-103,共13页
Background:Statins are the cornerstone of low-density lipoprotein cholesterol(LDL-C)-lowering therapy;however,the therapeutic efficacy of statins in countering atherosclerotic cardiovascular disease(ASCVD)is compromis... Background:Statins are the cornerstone of low-density lipoprotein cholesterol(LDL-C)-lowering therapy;however,the therapeutic efficacy of statins in countering atherosclerotic cardiovascular disease(ASCVD)is compromised by the concurrent elevation of proprotein convertase subtilisin/kexin type 9(PCSK9),a pivotal molecule that increases LDL-C levels.Aerobic exercise lowers PCSK9 levels,but the underlying mechanism remains unclear.Therefore,we investigated how aerobic exercise can ameliorate statin-induced increases in PCSK9 levels.Methods:Three-week-old male American Institute of Cancer Research(ICR)mice were fed a high-fat-cholesterol diet(HFD)for 12 weeks and then administered atorvastatin alone or atorvastatin combined with aerobic exercise(Statin+Ex).Moreover,a total of 165 participants with stable coronary heart disease(CHD)enrolled at the Inpatient and Outpatient Departments of the Second Xiangya Hospital of Central South University,China,from January 2018 to July 2020 were randomized into the Statin group(male/female=51/33)and Statin+Ex group(male/female=52/29).Patients in the Statin+Ex group underwent treadmill exercise of 45-60 min/day for 7 days.Results:Aerobic exercise effectively alleviated statin-induced PCSK9 upregulation in human patients with CHD and hypercholesterolemic ICR mice(all p<0.05).Mechanistically,our findings revealed that aerobic exercise induced elevated epoxyeicosatrienoic acids(EETs)plasma levels while concurrently reducing the activity of soluble epoxide hydrolase(sEH)(all p<0.05),an enzyme responsible for EETs degradation.Further,EETs significantly suppressed PCSK9 expression,subsequently reducing the LDL-C levels(all p<0.05);this effect was mediated via the activation of the forkhead box O3a-silent mating type information regulation 2 homolog 6(FoxO3a-Sirt6)axis,with no impact on the sterol regulatory element binding protein 2 and 3-hydroxy-3-methylglutaryl-CoA reductase(SREBP2-HMGCR)pathway.Conclusion:Our study sheds light on the paradigm of"Exercise is Medicine",providing evidence to support the use of statins combined with exercise in reducing LDL-C levels,and unveils potential avenues for clinical applications of sEH inhibitors,presenting novel prospects for therapeutic interventions in ASCVD. 展开更多
关键词 Aerobic exercise EETS FOXO3A PCSK9 Sirt6
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Mitochondrial and cardiovascular responses to aerobic exercise training in supine and upright positions in healthy young adults:a randomized parallel arm trial
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作者 Nicholas Preobrazenski Stuart P.S.Mladen +5 位作者 Ejaz Causer Eveline Menezes Hashim Islam Patrick J.Drouin Michael E.Tschakovsky Brendon J.Gurd 《Translational Exercise Biomedicine》 2025年第1期9-20,共12页
Objectives:Aerobic exercise training can increase skeletal muscle mitochondrial content.Supine exercise training with legs above the heart potentially augments these increases.However,the impact of supine exercise tra... Objectives:Aerobic exercise training can increase skeletal muscle mitochondrial content.Supine exercise training with legs above the heart potentially augments these increases.However,the impact of supine exercise training on mitochondrial biogenesis and cardiovascular adaptations remains unclear.Methods:In this single-centred,randomized,parallel arm trial,19 recreationally active individuals underwent seven sessions of either supine with legs up(SUP;n=9,6 females)or upright with legs down(UP;n=10,7 females)aerobic training on a recumbent bike at 71±7%and 71±2%of peak work rate(WRpeak),respectively.The study aimed to test the effects of training with decreased muscle oxygenation on indices of muscle mitochondrial remodelling.Secondary outcomes included exercise performance,muscle oxygenation,and cardiovascular responses.Results:Secondary outcomes revealed significant interaction effects for time to fatigue(TTF)and WRpeak in the SUP group during supine testing,suggesting enhanced exercise tolerance and performance.No between group interaction effects were observed for upright testing.No clear effects on mitochondrial biogenesis were observed based on expression of mitochondrial protein subunits and transcriptional regulators.Acutely,HRpeak was lower during the SUP Test compared to the UP Test.No central cardiovascular adaptations were observed following training.Conclusions:Our exploratory analyses showed that supine aerobic training more effectively improves supine exercise tolerance and performance compared with upright training,despite no differences in measured proteins related to mitochondrial biogenesis.Further research is needed to elucidate the mechanisms underlying these postural-specific training effects.Registration:clinicaltrials.gov:NCT04151095. 展开更多
关键词 PGC-1Α supine exercise exercise performance aerobic training cardiovascular response
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Peripheral NV-induced electron transfer to Fe1 single atoms for highly efficient O_(2)activation
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作者 Fenli Liu Man Yang +12 位作者 Jianglin Duan Zhiyu Yin Mingyang Shi Fuqing Chen Huifeng Xiong Xin Liu Wengang Liu Qixing Xia Shaodong Sun Dan Feng Haifeng Qi Yong Qin Yujing Ren 《Chinese Journal of Catalysis》 2025年第5期187-198,共12页
Catalytic oxidation plays a crucial role in chemical industry,in which the utilization of abundant and environmental-friendly oxygen(O_(2))as oxidant aligns with sustainable development principles in green chemistry.H... Catalytic oxidation plays a crucial role in chemical industry,in which the utilization of abundant and environmental-friendly oxygen(O_(2))as oxidant aligns with sustainable development principles in green chemistry.However,the intrinsic inertness of ground-state O_(2) molecule poses a long-standing challenge in developing an efficient non-noble metal-based catalyst.Herein,inspired by the electron transfer process in respiratory chain,we engineered long-range N_(V) to mediate Fe_(1) center for O_(2) activation in aerobic oxidation.Combined in/quasi-situ spectroscopic characterizations and control experiments suggest the Fe_(1) site efficiently adsorbs O_(2),and the N_(V) site facilitates electron delocalization to adjacent Fe_(1),providing efficient transformation of O_(2) to reactive oxygen species that boost oxidation reactions mildly.This Fe_(1)--N_(V) single-atom catalyst demonstrates outstanding catalytic performance in aerobic oxidations of alkanes,N-heterocycles,alcohols,and amines under relatively mild conditions.Our findings offer a new perspective for designing high-efficiency heterogeneous catalysts in aerobic oxidations,promising various potential applications. 展开更多
关键词 Single-atom catalyst Peripheral-nitrogen effect Long-range NV Synergistic catalysis Aerobic oxidation
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Feasibility and clinical potential of exercise interventions during neoadjuvant chemoradiotherapy in patients with esophageal and rectal cancer
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作者 Isa H.Mast Elske C.Gootjes +10 位作者 Heidi Rütten Mariska Dden Hartogh Calvin G.Brouwer Iris D.Nagtegaal Rachel Svan der Post Maria T.E.Hopman Baukje van den Heuvel Camiel Rosman Johannes H.Wde Wilt Bastiaan R.Klarenbeek Laurien M.Buffart 《Journal of Sport and Health Science》 2025年第6期55-66,167,共13页
Background Exercise during neoadjuvant chemoradiotherapy(NCRT)has potential to mitigate treatment-related declines in physical fitness,and to improve clinical outcomes,including toxicity and tumor response.However,opt... Background Exercise during neoadjuvant chemoradiotherapy(NCRT)has potential to mitigate treatment-related declines in physical fitness,and to improve clinical outcomes,including toxicity and tumor response.However,optimal frequency and timing of exercise remains to be determined.Therefore,this pilot trial aimed to assess feasibility of 2 different exercise interventions during NCRT in patients with esophageal and rectal cancer and to evaluate potential clinical effects.Methods Patients were randomized into 1 of 3 study arms during NCRT:(a)30-min aerobic exercise in-hospital within 1 h prior to each radiotherapy fraction(ExPR),(b)two 60-min supervised combined aerobic and resistance exercise sessions per week(AE+RE),and(c)usual care(UC).Feasibility was assessed by examining participation rate and exercise adherence.Intervention effects on physical fitness,health-related quality of life,treatment-related toxicity,and tumor response in patients with esophageal cancer were explored using regression analyses and 85%confidence intervals(85%CIs).Results Thirty-seven patients with esophageal cancer(participation rate=45%)and 2 patients with rectal cancer(participation rate=14%)were included.Median session attendance was 98%(interquartile range(IQR):96%–100%)in the ExPR and 78%(IQR:33%–100%)in the AE+RE group.We found clinically relevant benefits of exercise on maximal oxygen uptake(VO2_(max),mL/kg/min)(ExPR:β=9.7,85%CI:6.9–12.6;AE+RE:β=5.6,85%CI:2.6–8.5)and treatment-related toxicity(ExPR:β=–2.8,85%CI:–5.4 to–0.2;AE+RE:β=–2.6,85%CI:–5.3 to 0.0).Additionally,good tumor response was found in 70%in AE+RE and ExPR vs.55%in UC(odds ratio(OR)=1.9,85%CI:0.5–7.7).Conclusion Starting prehabilitation during NCRT is feasible,can increase starting fitness of traditional pre-surgical programs,and has potential to improve clinical outcomes. 展开更多
关键词 Exercise intervention Esophageal cancer Aerobic capacity Treatment-related toxicity Tumor response
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Aerobic respiration Lactococcus lactis ameliorate Salmonella induced infection and intestinal dysfunctions by oxygen-scavenging and maintaining immune balance and regulating intestinal microbiota
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作者 Yulong Zhang Han Yang +3 位作者 Zhiliang Cheng Hui Ha Fei Liu Yuehua Jiao 《Food Science and Human Wellness》 2025年第6期2278-2294,共17页
Salmonella grows better under aerobic conditions as a facultative anaerobic foodborne pathogenic bacteria.The oxygen-scavenging activity of Lactococcus lactis in the intestinal tract is a promising strategy for preven... Salmonella grows better under aerobic conditions as a facultative anaerobic foodborne pathogenic bacteria.The oxygen-scavenging activity of Lactococcus lactis in the intestinal tract is a promising strategy for preventing Salmonella infection.In this study,the aerobic respiration requirement and preventive mechanism of L.lactis subsp.lactis KLDS 4.0325 in murine models infected by Salmonella enterica subsp.enterica serovar Typhimurium(S.Typhimurium)SL1344 were investigated.Results indicate that L.lactis KLDS 4.0325 is capable of aerobic respiratory metabolism in the host intestine when exogenous heme exists,and decrease intestinal oxygen concentration,which in turn trigger autophagy of intestinal cells to reduce S.Typhimurium load,improve gut microbiota composition,alleviate intestinal barrier injury and inflammation response.These results suggest that aerobic respiration L.lactis KLDS 4.0325 can prevent S.Typhimurium infection in a new way in which by restoring intestinal cell hypoxia,maintaining immune balance and regulating intestinal flora. 展开更多
关键词 Lactococcus lactis Aerobic respiration SALMONELLA Intestinal flora
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Validation of marathon performance model based on physiological factors in world-class East African runners:a case series
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作者 Melanie Knopp Fergus Guppy +5 位作者 Michael Joyner Borja Muniz-Pardos Henning Wackerhage Martin Schönfelder Yannis Pitsiladis Daniel Ruiz 《Translational Exercise Biomedicine》 2025年第1期1-8,共8页
Objectives:The aim of this study was to compare the measured physiological factors that limit running performance with real marathon results from world-class distance runners,evaluating the compatibility between measu... Objectives:The aim of this study was to compare the measured physiological factors that limit running performance with real marathon results from world-class distance runners,evaluating the compatibility between measured data and predicted results based on the previously suggested model.Methods:Four world-class East African marathon runners(three male,one female)underwent physiological running assessments to predict marathon performance times using a model based on˙V O_(2)peak,percentage of˙V O_(2)peak at the second ventilatory threshold,and running economy.Predictions were then compared to participants’best marathon times.Results:The measured˙V O_(2)peak of the world-class runners was 75.1±2.7 mL/kg/min.The second ventilatory threshold occurred at 85±3%of the peak,with a running economy of 63.7±2.4 mL/kg/min at 19.6±0.9 km/h.The predicted marathon performance time was 2:06:51±0:03:17 h:min:s for the males and 2:17:36 h:min:s for the female.Comparing these predictions to their personal best times,the average difference was 00:55±00:51 min:s(range:00:20-02:08).Conclusions:This research provides laboratory data on world-class road running athletes,reinforcing the link between marathon performance and˙V O_(2)peak,the percentage of˙VO_(2)peak at the second ventilatory threshold,and running economy.The examined athletes had lower˙V O_(2)peak compared to predicted values,highlighting the importance of running economy and fractional utilization of˙V O_(2)peak in achieving such performances.Future studies should continue to advance the field by including additional bioenergetic parameters measured during race conditions and expanding the participant cohort of elite marathoners,encompassing both sexes. 展开更多
关键词 marathon performance predictive model peak aerobic capacity second ventilatory threshold running economy marathon running
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