Methamphetamine(METH)addiction is a severe and increasingly prevalent neuropsychiatric disorder for which current diagnostic and therapeutic approaches remain limited and predominantly symptom-oriented.Exercise,as a s...Methamphetamine(METH)addiction is a severe and increasingly prevalent neuropsychiatric disorder for which current diagnostic and therapeutic approaches remain limited and predominantly symptom-oriented.Exercise,as a safe,accessible and cost-effective non-pharmacological intervention,has emerged as a promising strategy to ameliorate METH-induced neurotoxicity and addiction-related behaviors.Growing evidence indicates that these benefits are closely linked to the regulation of exercise-induced biomarkers,defined as molecular indicators whose expression or activity is dynamically altered during or after physical activity.This review focuses on the core regulatory role of exercise-induced biomarkers in METH addiction and systematically summarizes their involvement in key neurobiological pathways,outlining molecular pathological mechanisms such as dysregulation of dopamine,glutamate and GABA neurotransmitter systems,neuroinflammation and oxidative stress,and epigenetic remodeling,and emphasizing how these processes converge on changes in candidate biomarkers in the brain and periphery.On this basis,the review describes how exercise modulates neural plasticity,neurotransmitter systems,inflammation and oxidative stress through biomarkers such as brain-derived neurotrophic factor(BDNF),exerkines,inflammatory cytokines,metabolites and noncoding RNAs,with particular attention to neurotrophic and immune-related markers,microRNAs and other epigenetic regulators that can reverse METH-induced synaptic and structural abnormalities and promote recovery of cognitive and emotional functions.Advances in high-throughput omics technologies,including transcriptomics,metabolomics and multi-omics integration,are summarized to illustrate the screening and identification of key exercise-responsive biomarkers.Studies in METH-addicted animal models have revealed differentially expressed genes,signaling pathways(e.g.,PI3K-Akt,mTOR,Wnt)and core nodes such as NFKBIA and CXCL12 that may mediate the protective effects of exercise.The review further discusses the potential of exercisemediated biomarkers as objective indicators for diagnosis,dynamic monitoring of therapeutic efficacy and patient stratification.Multi-gene diagnostic models based on peripheral samples(e.g.,hair follicles,blood)demonstrate how biomarker panels can distinguish non-recovered,almost-recovered and healthy individuals,providing a molecular basis for staging METH use disorder and evaluating the impact of exercise interventions.The temporal dynamics of biomarker changes before and after exercise are highlighted,underscoring the value of longitudinal monitoring of factors such as BDNF,immune-related genes and circulating microRNAs to capture treatment-relevant windows of plasticity.In addition,the underlying molecular basis of exercise as an adjunct therapy and gene-targeted exercise strategies that leverage individual biomarker and gene expression profiles to optimize exercise prescriptions are summarized.Current conceptual and technical challenges are outlined,including heterogeneity of biomarker responses,individual variability,assay sensitivity and specificity,and gaps between preclinical findings and clinical application,together with future directions for integrating exercise with multi-omics,artificial intelligence-assisted biomarker discovery and,prospectively,gene-editing-based interventions.Particular emphasis is placed on the need to standardize exercise protocols,incorporate stage-specific and sex-sensitive designs,and combine exercise with pharmacotherapy and psychosocial rehabilitation in real-world clinical settings across diverse healthcare systems.Overall,this review aims to provide a comprehensive and integrated mechanistic framework and updated theoretical support for the application of exercise-mediated biomarkers in the diagnosis,therapeutic effect monitoring and personalized intervention of METH addiction,and to offer new and clinically relevant insights into the development of precision medicine strategies for substance use disorders.展开更多
Objectives:The addiction of the student population to short-form video platforms such as TikTok(Douyin)is becoming increasingly apparent and is rapidly expanding.This emerging addiction is also believed to have negati...Objectives:The addiction of the student population to short-form video platforms such as TikTok(Douyin)is becoming increasingly apparent and is rapidly expanding.This emerging addiction is also believed to have negative impacts on students’academic,social,and emotional well-being.Consequently,video addiction has become an important public health issue on campuses around the world.Therefore,this study aimed to investigate the relationship between two types of TikTok addiction(video and live streaming)and social and emotional learning(SEL),including self-awareness,self-management,social awareness,relationship skills,and responsible decision-making.Methods:Previous research has indicated that some students at vocational colleges become addicted to short-form videos.Accordingly,this study employed a snowball sampling method to survey students at vocational institutions across China.A total of 563 valid responses were obtained,yielding an effective response rate of 84.66%.The mean age of participants was 20.20 years old(SD=1.36).Data were validated with structural equation modeling.Results:Results showed that both video content addiction and live-streaming content addiction negatively correlatedwith all five dimensions of SEL.This also represents that all 10 hypotheses are valid and significant at p<0.001.Theeffect sizes ranged from 0.48 to 0.54,which represents larger effect sizes.Notably,TikTok addiction showed the strongest explanatory power for self-awareness.This indicates that higher levels of addiction to either video or live-streaming content are associatedwith poorer performance across all facets of social and emotional learning,including self-awareness,emotion regulation,interpersonal relationships,sense of responsibility,and empathy.Conclusion:This study found that TikTok addicts entered a state of ego depletion due to impaired self-regulation.This depletion then caused their subsequent self-control efforts during learning to fail.Our results also support the ego depletion theory,which posits that engaging in self-regulatory behaviors consumes limited self-control resources and can trigger a range of complex cognitive,emotional,and behavioral problems.This result also draws attention to the negative consequences of excessive use of short videos for social awareness and emotional performance.展开更多
Objectives:SocialNetworkAddiction(SNA)is becoming increasingly prevalent among college students;however,there remains a lack of consensus regarding the measurement tools and their optimal cutoff score.This study aims ...Objectives:SocialNetworkAddiction(SNA)is becoming increasingly prevalent among college students;however,there remains a lack of consensus regarding the measurement tools and their optimal cutoff score.This study aims to validate the 21-item SocialNetwork Addiction Scale-Chinese(SNAS-C)in its Chinese version and to determine its optimal cutoff score for identifying potential SNA cases within the college student population.Methods:A crosssectional survey was conducted,recruiting 3387 college students.Latent profile analysis(LPA)and receiver operating characteristic(ROC)curve analysis were employed to establish the optimal cutoff score for the validated 21-item SNAS-C.Results:Three profile models were selected based on multiple statistical criteria,classifying participants into low-risk,moderate-risk,and high-risk groups.The highest-risk group was defined as“positive”for SNA,while the remaining groups were considered“negative”,serving as the reference standard for ROC analysis.The optimal cutoff score was determined to be 72(sensitivity:98.2%,specificity:96.86%),with an overall classification accuracy of 97.0%.The“positive”group reported significantly higher frequency of social network usage,greater digitalmedia dependence scores,and a higher incidence of network addiction.Conclusion:This study identified the optimal cutoff score for the SNAS-C as≥72,demonstrating high sensitivity,specificity,and diagnostic accuracy.This threshold effectively distinguishes between high-risk and low-risk SNA.展开更多
Objectives:Short video addiction has emerged as a significant public health issue in recent years,with a growing trend toward severity.However,research on the causes and impacts of short video addiction remains limite...Objectives:Short video addiction has emerged as a significant public health issue in recent years,with a growing trend toward severity.However,research on the causes and impacts of short video addiction remains limited,and understanding of the variable“TikTok brain”is still in its infancy.Therefore,based on the Stimulus-Organism-Behavior-Consequence(SOBC)framework,we proposed six research hypotheses and constructed a model to explore the relationships between short video usage intensity,TikTok brain,short video addiction,and decreased attention control.Methods:Given that students are considered a high-risk group for excessive short video use,we collected 1086 valid participants from Chinese student users,including 609 males(56.1%)and 477 females(43.9%),with an average participant age of 19.84 years,to test the hypotheses.Results:(1)Short video usage intensity was positively related to short video addiction,TikTok brain,and decreased attention control;(2)TikTok brain was positively related to short video addiction and decreased attention control;and(3)Short video addiction was positively related to decreased attention control.Conclusions:These findings suggest that although excessive use of short video applications brings negative consequences,users still spend significant amounts of time on these platforms,indicating a need for strict self-regulation of usage time.展开更多
BACKGROUND The prevalence of addiction makes it a significant public health issue.Recently,transcranial magnetic stimulation(TMS)has garnered significant attention as a promising treatment for addiction.AIM To analyze...BACKGROUND The prevalence of addiction makes it a significant public health issue.Recently,transcranial magnetic stimulation(TMS)has garnered significant attention as a promising treatment for addiction.AIM To analyze development trends and research hotspots in TMS-based addiction treatment using a bibliometric approach.METHODS Articles on TMS-based addiction treatment from 2001 to 2023 were sourced from the Science Citation Index Expanded in the Web of Science Core Collection.CiteSpace software,VOSviewer,the"bibliometrix"R software package,and the bibliometric online analysis platform were used to analyze the current publication trends and hotspots.RESULTS Total 190 articles on TMS-based addiction treatment were identified,with clinical studies being the most prevalent.The United States led in both publication volume and international collaborations.Medical University of South Carolina and Zangen A were the most productive institution and author,respectively.Neurobiology,alcohol use disorder,and repetitive TMS were the most recent research hotspots.CONCLUSION Future research should focus on the neurobiological mechanisms underlying TMS-based addiction treatment.This study offers comprehensive insights and recommendations for advancing research on TMS-based addiction treatment.展开更多
Background:In recent years,there has been increased research interest in both smartphone addiction and social media addiction as well as the development of psychometric instruments to assess these constructs.However,t...Background:In recent years,there has been increased research interest in both smartphone addiction and social media addiction as well as the development of psychometric instruments to assess these constructs.However,there is a lack of psychometric evaluation for instruments assessing smartphone addiction and social media addiction in Thailand.The present study evaluated the psychometric properties and gender measurement invariance of the Thai version of the Smartphone Application-Based Addiction Scale(SABAS)and Bergen Social Media Addiction Scale(BSMAS).Method:A total of 801 Thai university students participated in an online survey from January 2022 to July 2022 which included demographic information,SABAS,BSMAS,and the Internet Gaming Disorder Scale-Short Form(IGDS9-SF).Results:Confirmatory Factor Analyses(CFAs)found that both the SABAS and BSMAS had a one-factor structure.Findings demonstrated adequate psychometric properties of both instruments and also supported measurement invariance across genders.Moreover,scores on the SABAS and BSMAS were correlated with scores on the IGDS9-SF.Conclusion:The results indicated that the SABAS and BSMAS are useful psychometric instruments for assessing the risk of smartphone addiction and social media addiction among Thai young adults.展开更多
Understanding the cellular mechanisms of drug addiction remains a key task in current brain research.While neuron-based mechanisms have been extensively explored over the past three decades,recent evidence indicates a...Understanding the cellular mechanisms of drug addiction remains a key task in current brain research.While neuron-based mechanisms have been extensively explored over the past three decades,recent evidence indicates a critical involvement of astrocytes,the main type of non-neuronal cells in the brain.In response to extracellular stimuli,astrocytes modulate the activity of neurons,synaptic transmission,and neural network properties,collectively influencing brain function.G protein-coupled receptors(GPCRs)expressed on astrocyte surfaces respond to neuron-and environment-derived ligands by activating or inhibiting astrocytic signaling,which in turn regulates adjacent neurons and their circuitry.In this review,we focus on the dopamine D1 receptors(D1R)and metabotropic glutamate receptor 5(mGLUR5 or GRM5)—two GPCRs that have been critically implicated in the acquisition and maintenance of addiction-related behaviors.Positioned as an introductory-level review,this article briefly discusses astrocyte biology,outlines earlier discoveries about the role of astrocytes in substance-use disorders(SUDs),and provides detailed discussion about astrocytic D1Rs and mGLUR5s in regulating synapse and network functions in the nucleus accumbens(NAc)—a brain region that mediates addictionrelated emotional and motivational responses.This review serves as a stepping stone for readers of Engineering to explore links between astrocytic GPCRs and drug addiction and other psychiatric disorders.展开更多
Overeating is a risk factor and a management challenge in adiposity-based chronic disease(ABCD).Acupuncture has shown high safety and reliable clinical evidence in addressing overeating,and it is the promising potenti...Overeating is a risk factor and a management challenge in adiposity-based chronic disease(ABCD).Acupuncture has shown high safety and reliable clinical evidence in addressing overeating,and it is the promising potential non-pharmacological intervention.However,the mechanism underlying its effects has not been sufficiently summarized.The addiction model offers a framework to elucidate the mechanism of this aberrant eating behavior and provides novel perspectives and breakthrough points for optimizing clinical acupuncture strategies in ABCD management.In the paper,through analyzing domestic and in-ternational relevant findings,the characteristics of overeating based on food addiction,the relationship between overeating and ABCD,and the potential effect mechanisms of acupuncture for FA have been re-viewed and summarized.Including adaptive balance of transmitters and hormones,functional networks,periphery-central connection,and cross-system interaction.In future studies,the maturely-developed ad-diction research methods should be adopted to deepen the exploration on the mechanism of acupuncture effect,addiction medicine should be leveraged to shatter the cognitive barriers surrounding acupuncture’s role in mind-body regulation for ABCD treatment,and the prevention and treatment of overeating via acupuncture should be organically integrated into multidisciplinary management strategies.展开更多
Addiction literacy equips older adults with the knowledge to navigate substance use risks amid unique challenges like polypharmacy and social isolation.With rising trends in cannabis use among this group,targeted educ...Addiction literacy equips older adults with the knowledge to navigate substance use risks amid unique challenges like polypharmacy and social isolation.With rising trends in cannabis use among this group,targeted education can promote safe practices and reduce preventable harms.By fostering open conversations and integrating addiction literacy into healthcare,providers can support informed decision-making.展开更多
Persistent and maladaptive drug-related memories represent a key component in drug addiction.Converging evidence from both preclinical and clinical studies has demonstrated the potential efficacy of the memory reconso...Persistent and maladaptive drug-related memories represent a key component in drug addiction.Converging evidence from both preclinical and clinical studies has demonstrated the potential efficacy of the memory reconsolidation updating procedure(MRUP),a non-pharmacological strategy intertwining two distinct memory processes:reconsolidation and extinction—alternatively termed“the memory retrieval-extinction procedure”.This procedure presents a promising approach to attenuate,if not erase,entrenched drug memories and prevent relapse.The present review delineates the applications,molecular underpinnings,and operational boundaries of MRUP in the context of various forms of substance dependence.Furthermore,we critically examine the methodological limitations of MRUP,postulating potential refinement to optimize its therapeutic efficacy.In addition,we also look at the potential integration of MRUP and neurostimulation treatments in the domain of substance addiction.Overall,existing studies underscore the significant potential of MRUP,suggesting that interventions predicated on it could herald a promising avenue to enhance clinical outcomes in substance addiction therapy.展开更多
BACKGROUND Excessive video game use,recognized as internet gaming disorder in Diagnostic and Statistical Manual of Mental Disorders,Fifth Edition and Gaming Disorder in International Classification of Diseases,11th Re...BACKGROUND Excessive video game use,recognized as internet gaming disorder in Diagnostic and Statistical Manual of Mental Disorders,Fifth Edition and Gaming Disorder in International Classification of Diseases,11th Revision,has raised concerns regarding its effects on individuals’social well-being.AIM To analyze the association between internet gaming disorder and social interaction across Western and Asian populations.METHODS The review examined 14 observational studies published between 2000 and 2025.It assessed the frequency and quality of face-to-face interactions,the shift towards online socialization,and the methodological quality of the included studies.RESULTS The findings generally indicate that gaming addiction is associated with a decrease in the frequency of offline social interaction.Addicted gamers reported spending less time with family and friends and experiencing increased isolation.Furthermore,the quality of social relationships appeared poorer,with addicted gamers reporting higher levels of loneliness,lower social support,and decreased relationship satisfaction.While online social interactions increased,they did not fully compensate for the loss of real-world connections.CONCLUSION This review highlights the potential of gaming addiction to negatively impact overall social lives,emphasizing the necessity for interventions focused on promoting real-world social engagement.展开更多
This study examined how social desirability responses confound the relationship between gender and social media addiction.A total of 496 college student social media users(females=310,62.5%,mean age=20.15,SD=1.26)comp...This study examined how social desirability responses confound the relationship between gender and social media addiction.A total of 496 college student social media users(females=310,62.5%,mean age=20.15,SD=1.26)completed an online questionnaire on Social Media Addiction and Social Desirability.Mediation analysis revealed that females were at higher risk for social media addiction.On the other hand,the indirect effect of gender on social media addiction via social desirability is associated with lower social media addiction,which suggests that social desirability had a suppression effect on social media addiction associated with gender.ANOVA results showed that females reported higher social media addiction scores than males in the low social desirability group;in the high group,gender differences were insignificant.This study’s unique contribution is to suggest that females are at higher risk than males for developing addictive social media behaviors.Based on this finding,student social media safety interventions should be gender sensitive to the social desirability effect on females who may hide their true addiction as a result.展开更多
Background and Objective Social anxiety arising from intensive social media usage(SMU)among adolescents and youth has gained extensive attention in recent years due to its negative influence on mental health and acade...Background and Objective Social anxiety arising from intensive social media usage(SMU)among adolescents and youth has gained extensive attention in recent years due to its negative influence on mental health and academic performance.In spite of that,there is a dearth regarding the etiology of SMU-related social anxiety.This study aims to further clarify the influence of introversion personality on SMU-related social anxiety and the mechanism underlying such an association and provide a new perspective for developing effective intervention strategies for the highly prevailing SMU-related anxiety among Chinese college students.Methods A cohort of 979 college students(266 males and 713 females)aged 20.90±1.91 years was enrolled in this cross-sectional study.Four measures including the"extroversion"domain of Eysenck Personality Questionnaire Revised,Short Scale(EPQ-R-S E),Interaction Anxiousness Scale(IAS),Mobile Phone Addiction Index(MPAI),and Social Anxiety Scale for Social Media Users(SAS-SMU)were used to evaluate the influence of introversion personality on SMU-related social anxiety that was potentially mediated sequentially by interaction anxiousness and mobile phone addiction.Hayes PROCESS was used for correlation and mediation analysis.Results Interaction anxiousness(indirect effect=-1.331,95%CI:-1.559--1.122)partially mediated the association between introversion personality and SMU-related social anxiety.Besides,a sequential mediation of interaction anxiousness and mobile phone addiction in the link between introversion personality and SMU-related social anxiety was revealed(indirect effect=-0.308,95%CI:-0.404--0.220).No significant mediating effect was found with mobile phone addiction in the association between introversion personality and SMU-related social anxiety.Conclusion Targeting interaction anxiousness and mobile phone addiction may represent an efficient strategy alleviating SMU-related social anxiety among Chinese college students with introversion personality.展开更多
Background:Live streaming has become a globally prevalent form of digital entertainment,particularly among young audiences,fostering new modes of online engagement through real-time interaction.However,excessive use m...Background:Live streaming has become a globally prevalent form of digital entertainment,particularly among young audiences,fostering new modes of online engagement through real-time interaction.However,excessive use may lead to addictive behaviors in certain users.Current research on live-streaming addiction remains limited,with prior studies focusing primarily on socio-psychological drivers rather than the role of technological affordances.To address this gap,this study develops a conceptual model based on socio-technical systems and attachment theory to investigate how emotional and functional attachment mediate the relationship between platform features and addictive behavior.Methods:A total of 533 valid responses were collected in a cross-sectional survey(mean age=26.4 years,standard deviation[SD]=4.7;53.8%female).Data were analyzed using structural equation modeling(SEM)to test the hypothesized relationships.Additionally,the potential mediating effects of emotional and functional attachment between the platform features and live-streaming addiction were examined using the Bootstrap method.Results:Social factors(perceived interactivity,β=0.204,p<0.001;perceived confirmation,β=0.379,p<0.001)and technical factors(perceived customization,β=0.227,p<0.001;perceived amusement,β=0.252,p<0.001;vicarious expression,β=0.352,p<0.001)significantly strengthen both emotional and functional attachment,which in turn positively predict live-streaming addiction(emotional attachment:β=0.468,p<0.001;functional attachment:β=0.393,p<0.001).Furthermore,emotional attachment exerted a stronger influence on addiction than functional attachment.Conclusions:These findings deepen the understanding of live-streaming addiction by integrating socio-technical perspectives and offer practical implications for stakeholders to mitigate negative outcomes through effective strategies.展开更多
Drug addiction, a disorder characterized by chronic relapse and compulsive drug use, poses a significant threat to public safety and human health. Addictive substances can be categorized as natural, semi-synthetic, or...Drug addiction, a disorder characterized by chronic relapse and compulsive drug use, poses a significant threat to public safety and human health. Addictive substances can be categorized as natural, semi-synthetic, or synthetic based on their origin. Additionally, they can be classified into three groups according to their pharmacological targets: opioids, hallucinogens, and cannabinoids that act on G-protein-coupled receptors (GPCRs);alcohols, nicotine, ketamine, barbiturates, and benzodiazepines (BDZs) that affect ligand-gated ion channel-type receptors;and psychostimulants that interact with monoamine transporters. Current treatments for drug addiction primarily include substitution therapy and non-pharmacological approaches. However, these methods have limitations, particularly in addressing the underlying causes of relapse. Several drugs in clinical trials have demonstrated potential therapeutic effects for addiction to opioids, heroin, cocaine, and other substances. This review examines the origins and pharmacological mechanisms of addiction to naturally-derived psychoactive substances (NPS) and provides an overview of recent advancements in pharmacotherapy for drug addiction.展开更多
Background:Social media addiction,one of the behavioural addictions,is a significant predictor of job performance.It has also been posited that individuals whose fundamental requirements(e.g.,sleep)are not sufficientl...Background:Social media addiction,one of the behavioural addictions,is a significant predictor of job performance.It has also been posited that individuals whose fundamental requirements(e.g.,sleep)are not sufficiently met andwho lack adequate support(e.g.,perceived social support)are incapable of effectivelyharnessing theirpotential.The primary objective of this study is to examine themediating effects of sleep disorder and perceived social support on the relationship between social media addiction and job performance.Furthermore,it seeks to explore the moderating effects of perceived social support on sleep disorders and job performance.Methods:The data were collected through the questionnairemethod,and data analysis was performed using SPSS 26.0.Moreover,statistical analysis encompasses correlation analysis,mediation,and moderation analysis.The data were gathered from 488 healthcare professionals(57.2%female),whose ages ranged from 24 to 56 years(Meanage±SD=37.86±6.71),using a convenience sample approach.Results:The results revealed significant relationships between social media addiction,job performance,perceived social support,and sleep disorder.The findings indicate that social media addiction negatively predicts job performance(β=−0.11,p<0.05).Sleep disorder(effect size=−0.02,95%CI=[−0.04,−0.00])and perceived social support(effect size=−0.01,95%CI=[−0.02,−0.00])mediate this relationship.Furthermore,perceived social supportmoderates the pathway between sleep disorder and job performance(index ofmoderatedmediation:−0.0040,95%CI=[−0.0070,−0.0010]).Conclusions:This study suggests that social media addiction negatively affects job performance through sleep disorders and perceived social support among healthcare professionals.The study’s findings are significant,as they suggest that treatments aimed at alleviating sleep disorders and enhancing perceived social support among medical workers may improve their job performance.展开更多
Background:Recent years have witnessed the rapid rise of TikTok,a short-video social platform,which has sparked concerns about its potential for misuse and addiction.TikTok addiction has been associated with various p...Background:Recent years have witnessed the rapid rise of TikTok,a short-video social platform,which has sparked concerns about its potential for misuse and addiction.TikTok addiction has been associated with various psychological and social issues.This study aims to explore the mediating role of social ostracism in the relationship between the Dark Triad(Machiavellianism,Psychopathy,and Narcissism)and TikTok addiction.Methods:Data were collected from 425 Chinese college students through convenience sampling,using three validated scales:the Dirty Dozen,the Social Ostracism Scale,and the Bergen Social Media Addiction Scale.Structural Equation Modeling(SEM)with AMOS 24 revealed significant patterns.Results:Narcissism had direct positive effects on both social ostracism(β0.115,p 0.01)and TikTok addiction(β0.223,p 0.05),while Psychopathy only had a direct positive effect=<=<on social ostracism(β0.147,p 0.05).Contrary to expectations,Machiavellianism did not show significant direct=<effects on either social ostracism(βp 0.05)or TikTok addiction(β0.135,p 0.05).Mediation analysis=-0.031,>=>confirmed that social ostracism acted as a positive mediator,amplifying the effects of Psychopathy(β0.049,p 0.05)=<and Narcissism(β0.052,p 0.01)on TikTok addiction.In other words,higher levels of Psychopathy and Narcissism=<were linked to greater experiences of social ostracism,which in turn were linked to higher levels of TikTok addiction.Conclusion:These findings suggest an important role for social ostracism in linking Narcissism and Psychopathy to TikTok addiction.Addressing social ostracism and these dark personality traits through targeted interventions may be important in reducing TikTok addiction risks among individuals with such traits.展开更多
In our previous studies, we showed that frontal lobe and brainstem functions were abnormal in online game addicts. In this study, 14 students with Internet addiction disorder and 14 matched healthy controls underwent ...In our previous studies, we showed that frontal lobe and brainstem functions were abnormal in online game addicts. In this study, 14 students with Internet addiction disorder and 14 matched healthy controls underwent proton-magnetic resonance spectroscopy to measure cerebral function. Results demonstrated that the ratio of N-acetylaspartate to creatine decreased, but the ratio of cho- line-containing compounds to creatine increased in the bilateral frontal lobe white matter in people with Internet addiction disorder. However, these ratios were mostly unaltered in the brainstem, suggesting that frontal lobe function decreases in people with Internet addiction disorder.展开更多
The electroencephalogram(EEG)rhythm and functional near-infrared spectroscopy(fNIRS)activation levels have not been compared between a healthy control group(HCG)and methamphetamine user group(MUG)with different addict...The electroencephalogram(EEG)rhythm and functional near-infrared spectroscopy(fNIRS)activation levels have not been compared between a healthy control group(HCG)and methamphetamine user group(MUG)with different addiction histories.This study used 64-electrode EEG and fNIRS to conduct an experiment that analyzed the resting and craving states.The EEG and fNIRS data of 56 participants were collected,including 14 healthy participants,14 methamphetamine users with an addiction history of 0.5–5 years,14 users with an addiction history of 5–10 years,and 14 users with an addiction history of 10–15 years.Isolated effective coherence(iCoh)within the brain network was used to process the EEG data.Statistical analysis was performed to compare differences in iCoh among the delta,theta,alpha,beta,and gamma bands and explore oxyhemoglobin activation levels in the ventrolateral prefrontal cortex,dorsolateral prefrontal cortex,orbitofrontal cortex,and frontopolar prefrontal cortex(FPC)of the control group.Finally,the Kmeans,Gaussian mixed model(GMM),linear discriminant analysis(LDA),support vector machine(SVM),Bayes,and convolutional neural networks(CNN)algorithms were used to classify methamphetamine users based on drug and neutral images.A 3-class accuracy was achieved.Changes in EEG and fNIRS activation levels of HCG and MUG with varied addiction histories were demonstrated.展开更多
基金supported by grants from The National Natural Science Foundation of China(82472611)The“14th Five Year Plan”Scientific Research and Innovation Team of Chengdu Sport University(23CXTD02)Sports Medicine Key Laboratory of Sichuan Province/Key Laboratory of Sports Medicine,General Administration of Sport of China(2025-A028)。
文摘Methamphetamine(METH)addiction is a severe and increasingly prevalent neuropsychiatric disorder for which current diagnostic and therapeutic approaches remain limited and predominantly symptom-oriented.Exercise,as a safe,accessible and cost-effective non-pharmacological intervention,has emerged as a promising strategy to ameliorate METH-induced neurotoxicity and addiction-related behaviors.Growing evidence indicates that these benefits are closely linked to the regulation of exercise-induced biomarkers,defined as molecular indicators whose expression or activity is dynamically altered during or after physical activity.This review focuses on the core regulatory role of exercise-induced biomarkers in METH addiction and systematically summarizes their involvement in key neurobiological pathways,outlining molecular pathological mechanisms such as dysregulation of dopamine,glutamate and GABA neurotransmitter systems,neuroinflammation and oxidative stress,and epigenetic remodeling,and emphasizing how these processes converge on changes in candidate biomarkers in the brain and periphery.On this basis,the review describes how exercise modulates neural plasticity,neurotransmitter systems,inflammation and oxidative stress through biomarkers such as brain-derived neurotrophic factor(BDNF),exerkines,inflammatory cytokines,metabolites and noncoding RNAs,with particular attention to neurotrophic and immune-related markers,microRNAs and other epigenetic regulators that can reverse METH-induced synaptic and structural abnormalities and promote recovery of cognitive and emotional functions.Advances in high-throughput omics technologies,including transcriptomics,metabolomics and multi-omics integration,are summarized to illustrate the screening and identification of key exercise-responsive biomarkers.Studies in METH-addicted animal models have revealed differentially expressed genes,signaling pathways(e.g.,PI3K-Akt,mTOR,Wnt)and core nodes such as NFKBIA and CXCL12 that may mediate the protective effects of exercise.The review further discusses the potential of exercisemediated biomarkers as objective indicators for diagnosis,dynamic monitoring of therapeutic efficacy and patient stratification.Multi-gene diagnostic models based on peripheral samples(e.g.,hair follicles,blood)demonstrate how biomarker panels can distinguish non-recovered,almost-recovered and healthy individuals,providing a molecular basis for staging METH use disorder and evaluating the impact of exercise interventions.The temporal dynamics of biomarker changes before and after exercise are highlighted,underscoring the value of longitudinal monitoring of factors such as BDNF,immune-related genes and circulating microRNAs to capture treatment-relevant windows of plasticity.In addition,the underlying molecular basis of exercise as an adjunct therapy and gene-targeted exercise strategies that leverage individual biomarker and gene expression profiles to optimize exercise prescriptions are summarized.Current conceptual and technical challenges are outlined,including heterogeneity of biomarker responses,individual variability,assay sensitivity and specificity,and gaps between preclinical findings and clinical application,together with future directions for integrating exercise with multi-omics,artificial intelligence-assisted biomarker discovery and,prospectively,gene-editing-based interventions.Particular emphasis is placed on the need to standardize exercise protocols,incorporate stage-specific and sex-sensitive designs,and combine exercise with pharmacotherapy and psychosocial rehabilitation in real-world clinical settings across diverse healthcare systems.Overall,this review aims to provide a comprehensive and integrated mechanistic framework and updated theoretical support for the application of exercise-mediated biomarkers in the diagnosis,therapeutic effect monitoring and personalized intervention of METH addiction,and to offer new and clinically relevant insights into the development of precision medicine strategies for substance use disorders.
基金supported by the First-Class Education Discipline Development of Beijing Normal University(Grant Numbers:YLXKPY-XSDW202408,YLXKPY-ZYSB202201).
文摘Objectives:The addiction of the student population to short-form video platforms such as TikTok(Douyin)is becoming increasingly apparent and is rapidly expanding.This emerging addiction is also believed to have negative impacts on students’academic,social,and emotional well-being.Consequently,video addiction has become an important public health issue on campuses around the world.Therefore,this study aimed to investigate the relationship between two types of TikTok addiction(video and live streaming)and social and emotional learning(SEL),including self-awareness,self-management,social awareness,relationship skills,and responsible decision-making.Methods:Previous research has indicated that some students at vocational colleges become addicted to short-form videos.Accordingly,this study employed a snowball sampling method to survey students at vocational institutions across China.A total of 563 valid responses were obtained,yielding an effective response rate of 84.66%.The mean age of participants was 20.20 years old(SD=1.36).Data were validated with structural equation modeling.Results:Results showed that both video content addiction and live-streaming content addiction negatively correlatedwith all five dimensions of SEL.This also represents that all 10 hypotheses are valid and significant at p<0.001.Theeffect sizes ranged from 0.48 to 0.54,which represents larger effect sizes.Notably,TikTok addiction showed the strongest explanatory power for self-awareness.This indicates that higher levels of addiction to either video or live-streaming content are associatedwith poorer performance across all facets of social and emotional learning,including self-awareness,emotion regulation,interpersonal relationships,sense of responsibility,and empathy.Conclusion:This study found that TikTok addicts entered a state of ego depletion due to impaired self-regulation.This depletion then caused their subsequent self-control efforts during learning to fail.Our results also support the ego depletion theory,which posits that engaging in self-regulatory behaviors consumes limited self-control resources and can trigger a range of complex cognitive,emotional,and behavioral problems.This result also draws attention to the negative consequences of excessive use of short videos for social awareness and emotional performance.
基金supported by the National Natural Science Foundation of China(Grant No.72364006).
文摘Objectives:SocialNetworkAddiction(SNA)is becoming increasingly prevalent among college students;however,there remains a lack of consensus regarding the measurement tools and their optimal cutoff score.This study aims to validate the 21-item SocialNetwork Addiction Scale-Chinese(SNAS-C)in its Chinese version and to determine its optimal cutoff score for identifying potential SNA cases within the college student population.Methods:A crosssectional survey was conducted,recruiting 3387 college students.Latent profile analysis(LPA)and receiver operating characteristic(ROC)curve analysis were employed to establish the optimal cutoff score for the validated 21-item SNAS-C.Results:Three profile models were selected based on multiple statistical criteria,classifying participants into low-risk,moderate-risk,and high-risk groups.The highest-risk group was defined as“positive”for SNA,while the remaining groups were considered“negative”,serving as the reference standard for ROC analysis.The optimal cutoff score was determined to be 72(sensitivity:98.2%,specificity:96.86%),with an overall classification accuracy of 97.0%.The“positive”group reported significantly higher frequency of social network usage,greater digitalmedia dependence scores,and a higher incidence of network addiction.Conclusion:This study identified the optimal cutoff score for the SNAS-C as≥72,demonstrating high sensitivity,specificity,and diagnostic accuracy.This threshold effectively distinguishes between high-risk and low-risk SNA.
基金supported by the International Joint Research Project of Huiyan International College,Faculty of Education,Beijing Normal University(Grant Number:ICER202102).
文摘Objectives:Short video addiction has emerged as a significant public health issue in recent years,with a growing trend toward severity.However,research on the causes and impacts of short video addiction remains limited,and understanding of the variable“TikTok brain”is still in its infancy.Therefore,based on the Stimulus-Organism-Behavior-Consequence(SOBC)framework,we proposed six research hypotheses and constructed a model to explore the relationships between short video usage intensity,TikTok brain,short video addiction,and decreased attention control.Methods:Given that students are considered a high-risk group for excessive short video use,we collected 1086 valid participants from Chinese student users,including 609 males(56.1%)and 477 females(43.9%),with an average participant age of 19.84 years,to test the hypotheses.Results:(1)Short video usage intensity was positively related to short video addiction,TikTok brain,and decreased attention control;(2)TikTok brain was positively related to short video addiction and decreased attention control;and(3)Short video addiction was positively related to decreased attention control.Conclusions:These findings suggest that although excessive use of short video applications brings negative consequences,users still spend significant amounts of time on these platforms,indicating a need for strict self-regulation of usage time.
基金Supported by National Natural Science Foundation of China,No.81973620Wenzhou Municipal Science and Technology Bureau,No.Y20220091.
文摘BACKGROUND The prevalence of addiction makes it a significant public health issue.Recently,transcranial magnetic stimulation(TMS)has garnered significant attention as a promising treatment for addiction.AIM To analyze development trends and research hotspots in TMS-based addiction treatment using a bibliometric approach.METHODS Articles on TMS-based addiction treatment from 2001 to 2023 were sourced from the Science Citation Index Expanded in the Web of Science Core Collection.CiteSpace software,VOSviewer,the"bibliometrix"R software package,and the bibliometric online analysis platform were used to analyze the current publication trends and hotspots.RESULTS Total 190 articles on TMS-based addiction treatment were identified,with clinical studies being the most prevalent.The United States led in both publication volume and international collaborations.Medical University of South Carolina and Zangen A were the most productive institution and author,respectively.Neurobiology,alcohol use disorder,and repetitive TMS were the most recent research hotspots.CONCLUSION Future research should focus on the neurobiological mechanisms underlying TMS-based addiction treatment.This study offers comprehensive insights and recommendations for advancing research on TMS-based addiction treatment.
基金This research was funded by the Ministry of Science and Technology,Taiwan(MOST 110-2410-H-006-115)the Higher Education Sprout Project,Ministry of Education to the Headquarters of University Advancement at National Cheng Kung University(NCKU)the 2021 Southeast and South Asia and Taiwan Universities Joint Research Scheme(NCKU 31),and the E-Da Hospital(EDAHC111004).
文摘Background:In recent years,there has been increased research interest in both smartphone addiction and social media addiction as well as the development of psychometric instruments to assess these constructs.However,there is a lack of psychometric evaluation for instruments assessing smartphone addiction and social media addiction in Thailand.The present study evaluated the psychometric properties and gender measurement invariance of the Thai version of the Smartphone Application-Based Addiction Scale(SABAS)and Bergen Social Media Addiction Scale(BSMAS).Method:A total of 801 Thai university students participated in an online survey from January 2022 to July 2022 which included demographic information,SABAS,BSMAS,and the Internet Gaming Disorder Scale-Short Form(IGDS9-SF).Results:Confirmatory Factor Analyses(CFAs)found that both the SABAS and BSMAS had a one-factor structure.Findings demonstrated adequate psychometric properties of both instruments and also supported measurement invariance across genders.Moreover,scores on the SABAS and BSMAS were correlated with scores on the IGDS9-SF.Conclusion:The results indicated that the SABAS and BSMAS are useful psychometric instruments for assessing the risk of smartphone addiction and social media addiction among Thai young adults.
基金partially supported by the National Institutes of Health(NIH)grants DA056213(to Alexander K.Zinsmaier),DA053388(to Eric J.Nestler),DA023206(to Yan Dong),DA060868(to Yan Dong),and DA040620(to Eric J.Nestler and Yan Dong)。
文摘Understanding the cellular mechanisms of drug addiction remains a key task in current brain research.While neuron-based mechanisms have been extensively explored over the past three decades,recent evidence indicates a critical involvement of astrocytes,the main type of non-neuronal cells in the brain.In response to extracellular stimuli,astrocytes modulate the activity of neurons,synaptic transmission,and neural network properties,collectively influencing brain function.G protein-coupled receptors(GPCRs)expressed on astrocyte surfaces respond to neuron-and environment-derived ligands by activating or inhibiting astrocytic signaling,which in turn regulates adjacent neurons and their circuitry.In this review,we focus on the dopamine D1 receptors(D1R)and metabotropic glutamate receptor 5(mGLUR5 or GRM5)—two GPCRs that have been critically implicated in the acquisition and maintenance of addiction-related behaviors.Positioned as an introductory-level review,this article briefly discusses astrocyte biology,outlines earlier discoveries about the role of astrocytes in substance-use disorders(SUDs),and provides detailed discussion about astrocytic D1Rs and mGLUR5s in regulating synapse and network functions in the nucleus accumbens(NAc)—a brain region that mediates addictionrelated emotional and motivational responses.This review serves as a stepping stone for readers of Engineering to explore links between astrocytic GPCRs and drug addiction and other psychiatric disorders.
基金Supported by National Natural Science Foundation of China:82405556,82174527the National Traditional Chinese Medicine Advantage Specialized Department Construction Project:Yue TCM[2024]No.2+4 种基金the China Postdoctoral Science Foundation General Project:2024M750464Guangdong Basic and Applied Basic Research Foundation:2023A1515110682Jin-Xiong Lao Guangdong Provincial Famous Chinese Medicine Practitioner Heritage Studio:Yue TCM Office Document[2023]No.108Jin-Xiong Lao Foshan City Famous Chinese Medicine Practitioner Heritage Studio:Foshan Health Office Document[2022]No.106Foshan City's 14th 5-Year Plan Chinese Medicine Key Specialized Construction Projects:Foshan Health Office Document[2020]No.15。
文摘Overeating is a risk factor and a management challenge in adiposity-based chronic disease(ABCD).Acupuncture has shown high safety and reliable clinical evidence in addressing overeating,and it is the promising potential non-pharmacological intervention.However,the mechanism underlying its effects has not been sufficiently summarized.The addiction model offers a framework to elucidate the mechanism of this aberrant eating behavior and provides novel perspectives and breakthrough points for optimizing clinical acupuncture strategies in ABCD management.In the paper,through analyzing domestic and in-ternational relevant findings,the characteristics of overeating based on food addiction,the relationship between overeating and ABCD,and the potential effect mechanisms of acupuncture for FA have been re-viewed and summarized.Including adaptive balance of transmitters and hormones,functional networks,periphery-central connection,and cross-system interaction.In future studies,the maturely-developed ad-diction research methods should be adopted to deepen the exploration on the mechanism of acupuncture effect,addiction medicine should be leveraged to shatter the cognitive barriers surrounding acupuncture’s role in mind-body regulation for ABCD treatment,and the prevention and treatment of overeating via acupuncture should be organically integrated into multidisciplinary management strategies.
基金Supported by FAPESP and Conselho Nacional de Desenvolvimento Cientifico e Tecnologico,No.2024/13209-0.
文摘Addiction literacy equips older adults with the knowledge to navigate substance use risks amid unique challenges like polypharmacy and social isolation.With rising trends in cannabis use among this group,targeted education can promote safe practices and reduce preventable harms.By fostering open conversations and integrating addiction literacy into healthcare,providers can support informed decision-making.
基金supported by the National Natural Science Foundation of China(82071498,81871046,and 32161143022)STI2030-Major Projects(2022ZD0214500).
文摘Persistent and maladaptive drug-related memories represent a key component in drug addiction.Converging evidence from both preclinical and clinical studies has demonstrated the potential efficacy of the memory reconsolidation updating procedure(MRUP),a non-pharmacological strategy intertwining two distinct memory processes:reconsolidation and extinction—alternatively termed“the memory retrieval-extinction procedure”.This procedure presents a promising approach to attenuate,if not erase,entrenched drug memories and prevent relapse.The present review delineates the applications,molecular underpinnings,and operational boundaries of MRUP in the context of various forms of substance dependence.Furthermore,we critically examine the methodological limitations of MRUP,postulating potential refinement to optimize its therapeutic efficacy.In addition,we also look at the potential integration of MRUP and neurostimulation treatments in the domain of substance addiction.Overall,existing studies underscore the significant potential of MRUP,suggesting that interventions predicated on it could herald a promising avenue to enhance clinical outcomes in substance addiction therapy.
基金Supported by the Basic Science Research Program through the National Research Foundation of Korea Funded by the Ministry of Education,No.NRF-RS-2023-00237287。
文摘BACKGROUND Excessive video game use,recognized as internet gaming disorder in Diagnostic and Statistical Manual of Mental Disorders,Fifth Edition and Gaming Disorder in International Classification of Diseases,11th Revision,has raised concerns regarding its effects on individuals’social well-being.AIM To analyze the association between internet gaming disorder and social interaction across Western and Asian populations.METHODS The review examined 14 observational studies published between 2000 and 2025.It assessed the frequency and quality of face-to-face interactions,the shift towards online socialization,and the methodological quality of the included studies.RESULTS The findings generally indicate that gaming addiction is associated with a decrease in the frequency of offline social interaction.Addicted gamers reported spending less time with family and friends and experiencing increased isolation.Furthermore,the quality of social relationships appeared poorer,with addicted gamers reporting higher levels of loneliness,lower social support,and decreased relationship satisfaction.While online social interactions increased,they did not fully compensate for the loss of real-world connections.CONCLUSION This review highlights the potential of gaming addiction to negatively impact overall social lives,emphasizing the necessity for interventions focused on promoting real-world social engagement.
基金supported by the Guangdong Education Science Planning Project(2024GXJK612).
文摘This study examined how social desirability responses confound the relationship between gender and social media addiction.A total of 496 college student social media users(females=310,62.5%,mean age=20.15,SD=1.26)completed an online questionnaire on Social Media Addiction and Social Desirability.Mediation analysis revealed that females were at higher risk for social media addiction.On the other hand,the indirect effect of gender on social media addiction via social desirability is associated with lower social media addiction,which suggests that social desirability had a suppression effect on social media addiction associated with gender.ANOVA results showed that females reported higher social media addiction scores than males in the low social desirability group;in the high group,gender differences were insignificant.This study’s unique contribution is to suggest that females are at higher risk than males for developing addictive social media behaviors.Based on this finding,student social media safety interventions should be gender sensitive to the social desirability effect on females who may hide their true addiction as a result.
文摘Background and Objective Social anxiety arising from intensive social media usage(SMU)among adolescents and youth has gained extensive attention in recent years due to its negative influence on mental health and academic performance.In spite of that,there is a dearth regarding the etiology of SMU-related social anxiety.This study aims to further clarify the influence of introversion personality on SMU-related social anxiety and the mechanism underlying such an association and provide a new perspective for developing effective intervention strategies for the highly prevailing SMU-related anxiety among Chinese college students.Methods A cohort of 979 college students(266 males and 713 females)aged 20.90±1.91 years was enrolled in this cross-sectional study.Four measures including the"extroversion"domain of Eysenck Personality Questionnaire Revised,Short Scale(EPQ-R-S E),Interaction Anxiousness Scale(IAS),Mobile Phone Addiction Index(MPAI),and Social Anxiety Scale for Social Media Users(SAS-SMU)were used to evaluate the influence of introversion personality on SMU-related social anxiety that was potentially mediated sequentially by interaction anxiousness and mobile phone addiction.Hayes PROCESS was used for correlation and mediation analysis.Results Interaction anxiousness(indirect effect=-1.331,95%CI:-1.559--1.122)partially mediated the association between introversion personality and SMU-related social anxiety.Besides,a sequential mediation of interaction anxiousness and mobile phone addiction in the link between introversion personality and SMU-related social anxiety was revealed(indirect effect=-0.308,95%CI:-0.404--0.220).No significant mediating effect was found with mobile phone addiction in the association between introversion personality and SMU-related social anxiety.Conclusion Targeting interaction anxiousness and mobile phone addiction may represent an efficient strategy alleviating SMU-related social anxiety among Chinese college students with introversion personality.
基金funded by the Social Science Major Project of Tianjin Municipal Education Commission(Grant No.2025JWZD-GJ26).
文摘Background:Live streaming has become a globally prevalent form of digital entertainment,particularly among young audiences,fostering new modes of online engagement through real-time interaction.However,excessive use may lead to addictive behaviors in certain users.Current research on live-streaming addiction remains limited,with prior studies focusing primarily on socio-psychological drivers rather than the role of technological affordances.To address this gap,this study develops a conceptual model based on socio-technical systems and attachment theory to investigate how emotional and functional attachment mediate the relationship between platform features and addictive behavior.Methods:A total of 533 valid responses were collected in a cross-sectional survey(mean age=26.4 years,standard deviation[SD]=4.7;53.8%female).Data were analyzed using structural equation modeling(SEM)to test the hypothesized relationships.Additionally,the potential mediating effects of emotional and functional attachment between the platform features and live-streaming addiction were examined using the Bootstrap method.Results:Social factors(perceived interactivity,β=0.204,p<0.001;perceived confirmation,β=0.379,p<0.001)and technical factors(perceived customization,β=0.227,p<0.001;perceived amusement,β=0.252,p<0.001;vicarious expression,β=0.352,p<0.001)significantly strengthen both emotional and functional attachment,which in turn positively predict live-streaming addiction(emotional attachment:β=0.468,p<0.001;functional attachment:β=0.393,p<0.001).Furthermore,emotional attachment exerted a stronger influence on addiction than functional attachment.Conclusions:These findings deepen the understanding of live-streaming addiction by integrating socio-technical perspectives and offer practical implications for stakeholders to mitigate negative outcomes through effective strategies.
基金supported by the National Natural Science Foundation of China(No.82373836).
文摘Drug addiction, a disorder characterized by chronic relapse and compulsive drug use, poses a significant threat to public safety and human health. Addictive substances can be categorized as natural, semi-synthetic, or synthetic based on their origin. Additionally, they can be classified into three groups according to their pharmacological targets: opioids, hallucinogens, and cannabinoids that act on G-protein-coupled receptors (GPCRs);alcohols, nicotine, ketamine, barbiturates, and benzodiazepines (BDZs) that affect ligand-gated ion channel-type receptors;and psychostimulants that interact with monoamine transporters. Current treatments for drug addiction primarily include substitution therapy and non-pharmacological approaches. However, these methods have limitations, particularly in addressing the underlying causes of relapse. Several drugs in clinical trials have demonstrated potential therapeutic effects for addiction to opioids, heroin, cocaine, and other substances. This review examines the origins and pharmacological mechanisms of addiction to naturally-derived psychoactive substances (NPS) and provides an overview of recent advancements in pharmacotherapy for drug addiction.
文摘Background:Social media addiction,one of the behavioural addictions,is a significant predictor of job performance.It has also been posited that individuals whose fundamental requirements(e.g.,sleep)are not sufficiently met andwho lack adequate support(e.g.,perceived social support)are incapable of effectivelyharnessing theirpotential.The primary objective of this study is to examine themediating effects of sleep disorder and perceived social support on the relationship between social media addiction and job performance.Furthermore,it seeks to explore the moderating effects of perceived social support on sleep disorders and job performance.Methods:The data were collected through the questionnairemethod,and data analysis was performed using SPSS 26.0.Moreover,statistical analysis encompasses correlation analysis,mediation,and moderation analysis.The data were gathered from 488 healthcare professionals(57.2%female),whose ages ranged from 24 to 56 years(Meanage±SD=37.86±6.71),using a convenience sample approach.Results:The results revealed significant relationships between social media addiction,job performance,perceived social support,and sleep disorder.The findings indicate that social media addiction negatively predicts job performance(β=−0.11,p<0.05).Sleep disorder(effect size=−0.02,95%CI=[−0.04,−0.00])and perceived social support(effect size=−0.01,95%CI=[−0.02,−0.00])mediate this relationship.Furthermore,perceived social supportmoderates the pathway between sleep disorder and job performance(index ofmoderatedmediation:−0.0040,95%CI=[−0.0070,−0.0010]).Conclusions:This study suggests that social media addiction negatively affects job performance through sleep disorders and perceived social support among healthcare professionals.The study’s findings are significant,as they suggest that treatments aimed at alleviating sleep disorders and enhancing perceived social support among medical workers may improve their job performance.
基金reported in this paper represents a contribution to“Research Project on the Construction of Smart Teaching Capabilities in New Era Mingde College English(Grant No.2022YB0099)”at Henan Provincial Department of Education.
文摘Background:Recent years have witnessed the rapid rise of TikTok,a short-video social platform,which has sparked concerns about its potential for misuse and addiction.TikTok addiction has been associated with various psychological and social issues.This study aims to explore the mediating role of social ostracism in the relationship between the Dark Triad(Machiavellianism,Psychopathy,and Narcissism)and TikTok addiction.Methods:Data were collected from 425 Chinese college students through convenience sampling,using three validated scales:the Dirty Dozen,the Social Ostracism Scale,and the Bergen Social Media Addiction Scale.Structural Equation Modeling(SEM)with AMOS 24 revealed significant patterns.Results:Narcissism had direct positive effects on both social ostracism(β0.115,p 0.01)and TikTok addiction(β0.223,p 0.05),while Psychopathy only had a direct positive effect=<=<on social ostracism(β0.147,p 0.05).Contrary to expectations,Machiavellianism did not show significant direct=<effects on either social ostracism(βp 0.05)or TikTok addiction(β0.135,p 0.05).Mediation analysis=-0.031,>=>confirmed that social ostracism acted as a positive mediator,amplifying the effects of Psychopathy(β0.049,p 0.05)=<and Narcissism(β0.052,p 0.01)on TikTok addiction.In other words,higher levels of Psychopathy and Narcissism=<were linked to greater experiences of social ostracism,which in turn were linked to higher levels of TikTok addiction.Conclusion:These findings suggest an important role for social ostracism in linking Narcissism and Psychopathy to TikTok addiction.Addressing social ostracism and these dark personality traits through targeted interventions may be important in reducing TikTok addiction risks among individuals with such traits.
基金supported by the National Natural Science Foundation of China,No.30830046,30670751,30570695the National Science and Technology Program of China,No.2007BAI17B02+2 种基金the National 973 Program of China,No.2009CB918303the Natural Science Foundation of Hunan Province of China,No.07JJ3042Department of Public Health of Hunan Province of China,No.B2005048
文摘In our previous studies, we showed that frontal lobe and brainstem functions were abnormal in online game addicts. In this study, 14 students with Internet addiction disorder and 14 matched healthy controls underwent proton-magnetic resonance spectroscopy to measure cerebral function. Results demonstrated that the ratio of N-acetylaspartate to creatine decreased, but the ratio of cho- line-containing compounds to creatine increased in the bilateral frontal lobe white matter in people with Internet addiction disorder. However, these ratios were mostly unaltered in the brainstem, suggesting that frontal lobe function decreases in people with Internet addiction disorder.
基金supported by Shanghai Municipal Science and Technology Plan Project(No.22010502400)National Natural Science Foundation of China(Nos.82072228,92048205,and 62376149).
文摘The electroencephalogram(EEG)rhythm and functional near-infrared spectroscopy(fNIRS)activation levels have not been compared between a healthy control group(HCG)and methamphetamine user group(MUG)with different addiction histories.This study used 64-electrode EEG and fNIRS to conduct an experiment that analyzed the resting and craving states.The EEG and fNIRS data of 56 participants were collected,including 14 healthy participants,14 methamphetamine users with an addiction history of 0.5–5 years,14 users with an addiction history of 5–10 years,and 14 users with an addiction history of 10–15 years.Isolated effective coherence(iCoh)within the brain network was used to process the EEG data.Statistical analysis was performed to compare differences in iCoh among the delta,theta,alpha,beta,and gamma bands and explore oxyhemoglobin activation levels in the ventrolateral prefrontal cortex,dorsolateral prefrontal cortex,orbitofrontal cortex,and frontopolar prefrontal cortex(FPC)of the control group.Finally,the Kmeans,Gaussian mixed model(GMM),linear discriminant analysis(LDA),support vector machine(SVM),Bayes,and convolutional neural networks(CNN)algorithms were used to classify methamphetamine users based on drug and neutral images.A 3-class accuracy was achieved.Changes in EEG and fNIRS activation levels of HCG and MUG with varied addiction histories were demonstrated.
