Acta Geologica Sinica (English Edition) is a bimonthly,SCI-indexed academic journal produced by the Geological Society of China.With the latest 2023 Impact Factor of 2.1,it has long been indexed by many international ...Acta Geologica Sinica (English Edition) is a bimonthly,SCI-indexed academic journal produced by the Geological Society of China.With the latest 2023 Impact Factor of 2.1,it has long been indexed by many international databases and websites,such as SCI,CA,BIG,etc.Internationally,the journal cooperates with John Wiley&Sons,Inc.to publish the electronic version;all papers can be downloaded online.Contributors wishing to submit,read,enquire and download can log in via http://mc.manuscriptcentral.com/ags.展开更多
Acta Geologica Sinica(English Edition)is a bimonthly,SCI-indexed academic journal produced by the Geological Society of China.With the latest 2023 Impact Factor of 2.1,it has long been indexed by many international da...Acta Geologica Sinica(English Edition)is a bimonthly,SCI-indexed academic journal produced by the Geological Society of China.With the latest 2023 Impact Factor of 2.1,it has long been indexed by many international databases and websites,such as SCI,CA,BIG,etc.Internationally,the journal cooperates with John Wiley&Sons,Inc.to publish the electronic version;all papers can be downloaded online.Contributors wishing to submit,read,enquire and download can log in via http://mc.manuscriptcentral.com/ags.展开更多
Acta Pharmaceutica Sinica B(APSB)is delighted to announce that the 2024 Journal Impact Factor(JIF)of APSB is now 14.6(13.8 without self-citations)according to the latest Clarivate Journal Citation Reports released on ...Acta Pharmaceutica Sinica B(APSB)is delighted to announce that the 2024 Journal Impact Factor(JIF)of APSB is now 14.6(13.8 without self-citations)according to the latest Clarivate Journal Citation Reports released on Jun 18th,2025.APSB ranks No.6(Q1 quartile)of the 352 journals in the Pharmacology and Pharmacy category.展开更多
WITHDRAWAL:Zhang,J.J.,Guo,Y.Q.,Qin,Z.Y.,Wei,C.T.,Hu,Q.H.,Vandeginste,V.,Miao,H.Y.,Yao,P.,and Zhang,P.F.,“Predicting Irreducible Water Saturation of Unconventional Reservoirs by Using NMR T2 Spectra:Methods of Morphol...WITHDRAWAL:Zhang,J.J.,Guo,Y.Q.,Qin,Z.Y.,Wei,C.T.,Hu,Q.H.,Vandeginste,V.,Miao,H.Y.,Yao,P.,and Zhang,P.F.,“Predicting Irreducible Water Saturation of Unconventional Reservoirs by Using NMR T2 Spectra:Methods of Morphological Division and Fractal Models”,Acta Geologica Sinica-English Edition(Accepted Article):https://doi.org/10.1111/1755-6724.15094.展开更多
The 40th anniversary of Acta Mechanica Sinica(AMS)marks a milestone of the journal and its incessant pursuit of novelty and excellence.AMS strives for publishing reports pushing the knowledge boundaries and breaking e...The 40th anniversary of Acta Mechanica Sinica(AMS)marks a milestone of the journal and its incessant pursuit of novelty and excellence.AMS strives for publishing reports pushing the knowledge boundaries and breaking engineering limits where mechanics plays a vital role.展开更多
目的:本研究旨在观察转基因扩张型心肌病小鼠心肌组织Acta1、Col3a1基因及蛋白表达变化,探究真武汤防治扩张型心肌病的分子生物学机制。方法:将cT nT R141W基因转入C57BL/6J小鼠,建立了心肌组织特异表达cT nT R141W基因的转基因小鼠模型...目的:本研究旨在观察转基因扩张型心肌病小鼠心肌组织Acta1、Col3a1基因及蛋白表达变化,探究真武汤防治扩张型心肌病的分子生物学机制。方法:将cT nT R141W基因转入C57BL/6J小鼠,建立了心肌组织特异表达cT nT R141W基因的转基因小鼠模型,以C57BL/6J小鼠15只作为空白对照组,模型组小鼠60只,随机分为模型对照组、西药组、中药高剂量组及中药中剂量组,中药组以真武汤高中剂量对模型小鼠治疗4周,卡托普利为阳性对照药物。4周后采用qRT-PCR法检测各组心肌组织Acta1、Col3a1相对表达量; Western Blot法检测各组心肌组织Acta1、Col3a1蛋白表达。结果:与空白对照组比较模型对照组Acta1、Col3a1基因及蛋白表达显著升高(P <0. 01),与模型对照组比较西药组及中药高中剂量组Acta1、Col3a1基因及蛋白表达均显著下降(P <0. 01)。结论:DCM的发病机制与心肌组织中Acta1与Col3a1mRNA及蛋白表达升高有关,真武汤通过下调心肌组织中Acta1与Col3a1 mRNA及蛋白表达,抑制心肌细胞肥大及纤维化过程,起到防治DCM的作用。展开更多
文摘Acta Geologica Sinica (English Edition) is a bimonthly,SCI-indexed academic journal produced by the Geological Society of China.With the latest 2023 Impact Factor of 2.1,it has long been indexed by many international databases and websites,such as SCI,CA,BIG,etc.Internationally,the journal cooperates with John Wiley&Sons,Inc.to publish the electronic version;all papers can be downloaded online.Contributors wishing to submit,read,enquire and download can log in via http://mc.manuscriptcentral.com/ags.
文摘Acta Geologica Sinica(English Edition)is a bimonthly,SCI-indexed academic journal produced by the Geological Society of China.With the latest 2023 Impact Factor of 2.1,it has long been indexed by many international databases and websites,such as SCI,CA,BIG,etc.Internationally,the journal cooperates with John Wiley&Sons,Inc.to publish the electronic version;all papers can be downloaded online.Contributors wishing to submit,read,enquire and download can log in via http://mc.manuscriptcentral.com/ags.
文摘Acta Pharmaceutica Sinica B(APSB)is delighted to announce that the 2024 Journal Impact Factor(JIF)of APSB is now 14.6(13.8 without self-citations)according to the latest Clarivate Journal Citation Reports released on Jun 18th,2025.APSB ranks No.6(Q1 quartile)of the 352 journals in the Pharmacology and Pharmacy category.
文摘WITHDRAWAL:Zhang,J.J.,Guo,Y.Q.,Qin,Z.Y.,Wei,C.T.,Hu,Q.H.,Vandeginste,V.,Miao,H.Y.,Yao,P.,and Zhang,P.F.,“Predicting Irreducible Water Saturation of Unconventional Reservoirs by Using NMR T2 Spectra:Methods of Morphological Division and Fractal Models”,Acta Geologica Sinica-English Edition(Accepted Article):https://doi.org/10.1111/1755-6724.15094.
文摘The 40th anniversary of Acta Mechanica Sinica(AMS)marks a milestone of the journal and its incessant pursuit of novelty and excellence.AMS strives for publishing reports pushing the knowledge boundaries and breaking engineering limits where mechanics plays a vital role.
文摘目的:本研究旨在观察转基因扩张型心肌病小鼠心肌组织Acta1、Col3a1基因及蛋白表达变化,探究真武汤防治扩张型心肌病的分子生物学机制。方法:将cT nT R141W基因转入C57BL/6J小鼠,建立了心肌组织特异表达cT nT R141W基因的转基因小鼠模型,以C57BL/6J小鼠15只作为空白对照组,模型组小鼠60只,随机分为模型对照组、西药组、中药高剂量组及中药中剂量组,中药组以真武汤高中剂量对模型小鼠治疗4周,卡托普利为阳性对照药物。4周后采用qRT-PCR法检测各组心肌组织Acta1、Col3a1相对表达量; Western Blot法检测各组心肌组织Acta1、Col3a1蛋白表达。结果:与空白对照组比较模型对照组Acta1、Col3a1基因及蛋白表达显著升高(P <0. 01),与模型对照组比较西药组及中药高中剂量组Acta1、Col3a1基因及蛋白表达均显著下降(P <0. 01)。结论:DCM的发病机制与心肌组织中Acta1与Col3a1mRNA及蛋白表达升高有关,真武汤通过下调心肌组织中Acta1与Col3a1 mRNA及蛋白表达,抑制心肌细胞肥大及纤维化过程,起到防治DCM的作用。
