This article reviews the characteristics of psychological disorders in young and middle-aged acute coronary syndrome(ACS)patients,the mechanisms and effects of various psychological intervention strategies,factors inf...This article reviews the characteristics of psychological disorders in young and middle-aged acute coronary syndrome(ACS)patients,the mechanisms and effects of various psychological intervention strategies,factors influencing return to work,and current research problems and development trends,to provide scientific evidence for psychological rehabilitation and social function recovery of young and middle-aged ACS patients.展开更多
目的探讨芪参益气滴丸联合尼可地尔对急性冠脉综合征(ACS)患者经皮冠状动脉介入治疗(PCI)术后心功能、炎症因子水平及主要不良心血管事件(MACE)的影响。方法选取2022年4月至2024年4月常州市武进中医医院收治的80例ACS行PCI术患者,按随...目的探讨芪参益气滴丸联合尼可地尔对急性冠脉综合征(ACS)患者经皮冠状动脉介入治疗(PCI)术后心功能、炎症因子水平及主要不良心血管事件(MACE)的影响。方法选取2022年4月至2024年4月常州市武进中医医院收治的80例ACS行PCI术患者,按随机数字表法分为对照组(40例,常规治疗联合尼可地尔)与观察组(40例,常规治疗联合尼可地尔+芪参益气滴丸),两组均治疗4周。比较两组治疗前后心功能指标[左室射血分数(LVEF)、左室舒张末期内径(LVEDD)、N末端B型利钠肽前体(NT-proBNP)]、炎症因子[超敏C反应蛋白(hs-CRP)、白介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)]水平,随访6个月记录MACE发生率。结果治疗后,观察组LVEF显著高于对照组[(58.31±5.07 vs 53.22±4.78)%],差异有统计学意义(P<0.05),LVEDD、NT-proBNP、hs-CRP、IL-6、TNF-α水平以及MACE总发生率均显著低于对照组[(48.17±3.05 vs 51.32±3.41)mm,(452.63±89.42 vs 698.25±112.37)pg/mL,(2.13±0.58 vs 4.26±0.94)mg/L,(5.22±1.06 vs 8.75±1.43)pg/mL,(3.16±0.72 vs 6.32±1.15)pg/mL,7.50%vs 25.00%],差异有统计学意义(P<0.05)。结论芪参益气滴丸联合尼可地尔可有效改善ACS患者PCI术后心功能,抑制全身炎症反应,降低MACE风险,具有协同增效作用。展开更多
基金Supported by Humanities and Social Sciences Project of Hubei Provincial Department of Education(22Q149&19Y090).
文摘This article reviews the characteristics of psychological disorders in young and middle-aged acute coronary syndrome(ACS)patients,the mechanisms and effects of various psychological intervention strategies,factors influencing return to work,and current research problems and development trends,to provide scientific evidence for psychological rehabilitation and social function recovery of young and middle-aged ACS patients.
文摘目的探讨芪参益气滴丸联合尼可地尔对急性冠脉综合征(ACS)患者经皮冠状动脉介入治疗(PCI)术后心功能、炎症因子水平及主要不良心血管事件(MACE)的影响。方法选取2022年4月至2024年4月常州市武进中医医院收治的80例ACS行PCI术患者,按随机数字表法分为对照组(40例,常规治疗联合尼可地尔)与观察组(40例,常规治疗联合尼可地尔+芪参益气滴丸),两组均治疗4周。比较两组治疗前后心功能指标[左室射血分数(LVEF)、左室舒张末期内径(LVEDD)、N末端B型利钠肽前体(NT-proBNP)]、炎症因子[超敏C反应蛋白(hs-CRP)、白介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)]水平,随访6个月记录MACE发生率。结果治疗后,观察组LVEF显著高于对照组[(58.31±5.07 vs 53.22±4.78)%],差异有统计学意义(P<0.05),LVEDD、NT-proBNP、hs-CRP、IL-6、TNF-α水平以及MACE总发生率均显著低于对照组[(48.17±3.05 vs 51.32±3.41)mm,(452.63±89.42 vs 698.25±112.37)pg/mL,(2.13±0.58 vs 4.26±0.94)mg/L,(5.22±1.06 vs 8.75±1.43)pg/mL,(3.16±0.72 vs 6.32±1.15)pg/mL,7.50%vs 25.00%],差异有统计学意义(P<0.05)。结论芪参益气滴丸联合尼可地尔可有效改善ACS患者PCI术后心功能,抑制全身炎症反应,降低MACE风险,具有协同增效作用。
