随着微创治疗理念的发展,微创技术在急性胆源性胰腺炎(ABP)中的应用也逐渐得到青睐和广泛推广,但其在干预指征、方法及时机等方面仍有一定争议。本综述旨在对ABP的微创治疗,包括内镜治疗、微创手术、穿刺引流等手段的选择进行总结,为临...随着微创治疗理念的发展,微创技术在急性胆源性胰腺炎(ABP)中的应用也逐渐得到青睐和广泛推广,但其在干预指征、方法及时机等方面仍有一定争议。本综述旨在对ABP的微创治疗,包括内镜治疗、微创手术、穿刺引流等手段的选择进行总结,为临床实践及应用提供参考。ABP病情多变,应在保守治疗期间尽快完善相关检查,早期诊断并评估病情严重程度,针对不同病情采取相应的微创治疗,制定个体化方案,在恰当时机选择合适的微创方法或综合措施进行治疗。With the development of minimally invasive treatment concept, the application of minimally invasive techniques in acute biliary pancreatitis (ABP) has gradually been favored and widely promoted, but its intervention indications, methods and timing are still controversial. The purpose of this review is to summarize the selection of minimally invasive treatment for ABP, including endoscopic therapy, minimally invasive surgery, puncture drainage and other means, so as to provide reference for clinical practice and application. The condition of ABP is changeable, and relevant examinations should be improved as soon as possible during conservative treatment, early diagnosis and evaluation of the severity of the condition, corresponding minimally invasive treatment for different conditions, individualized plans, and appropriate minimally invasive methods or comprehensive measures should be selected at the right time for treatment.展开更多
Dear Editor,The primary objective of the letter is to emphasize the importance of personalized management of arterial blood pressure(ABP)in the context of off-pump coronary artery bypass grafting(CABG)surgery.Coronary...Dear Editor,The primary objective of the letter is to emphasize the importance of personalized management of arterial blood pressure(ABP)in the context of off-pump coronary artery bypass grafting(CABG)surgery.Coronary artery disease,a leading global cause of mortality,necessitates a substantial number of cardiac surgeries,with approximately 400,000 CABG operations conducted annually in the United States.Postoperative heart failure(HF)is a common occurrence after CABG surgery,with readmission rates within 30 d due to HF ranging from 12% to 16%.展开更多
The phytohormone auxin exerts control over remarkable developmental processes in plants.It moves from cell to cell,resulting in the creation of both extracellular auxin and intracellular auxin,which are recognized by ...The phytohormone auxin exerts control over remarkable developmental processes in plants.It moves from cell to cell,resulting in the creation of both extracellular auxin and intracellular auxin,which are recognized by distinct auxin receptors.These two auxin signaling systems govern different auxin responses while working together to regulate plant development.In this review,we outline the latest research advancements in unraveling these auxin signaling pathways,encompassing auxin perception and signaling transductions.We emphasize the interaction between extracellular and intracellular auxin,which contributes to the intricate role of auxin in plant development.展开更多
In this note,we prove a logarithmic Sobolev inequality which holds for compact submanifolds without a boundary in manifolds with asymptotically nonnegative sectional curvature.Like the Michale-Simon Sobolev inequality...In this note,we prove a logarithmic Sobolev inequality which holds for compact submanifolds without a boundary in manifolds with asymptotically nonnegative sectional curvature.Like the Michale-Simon Sobolev inequality,this inequality contains a term involving the mean curvature.展开更多
【目的】将抗逆相关转录因子ABP9基因导入大豆(Glycine max L.)基因组,并对转化系统条件进行探索,为提高大豆遗传转化效率提供依据。【方法】以农杆菌介导的半种法大豆遗传转化系统为基础,对目的基因进行转化;以健康外植体获得率、抗性...【目的】将抗逆相关转录因子ABP9基因导入大豆(Glycine max L.)基因组,并对转化系统条件进行探索,为提高大豆遗传转化效率提供依据。【方法】以农杆菌介导的半种法大豆遗传转化系统为基础,对目的基因进行转化;以健康外植体获得率、抗性丛生芽获得率和抗性芽伸长比率为指标,对转化系统条件进行优化。【结果】共培养时保证充足的光照和氧气,外植体生长情况最好;在共培养或诱导丛生芽培养基中加入600mg·L-1的L-半胱氨酸可以使抗性丛生芽获得率由22.1%提高至32.6%;采用4种植物激素进行正交试验,诱导抗性芽伸长比率最高的激素配比为:6-BA为1.5mg·L-1,GA3为0.75mg·L-1,IAA为0.1mg·L-1,ZT为1.0mg·L-1。【结论】利用优化的方法进行遗传转化研究已获得转基因再生植株,经PCR和DNA测序等分子检测,证明目的基因ABP9已导入并整合到大豆基因组中;转化率为1.33%。展开更多
文摘随着微创治疗理念的发展,微创技术在急性胆源性胰腺炎(ABP)中的应用也逐渐得到青睐和广泛推广,但其在干预指征、方法及时机等方面仍有一定争议。本综述旨在对ABP的微创治疗,包括内镜治疗、微创手术、穿刺引流等手段的选择进行总结,为临床实践及应用提供参考。ABP病情多变,应在保守治疗期间尽快完善相关检查,早期诊断并评估病情严重程度,针对不同病情采取相应的微创治疗,制定个体化方案,在恰当时机选择合适的微创方法或综合措施进行治疗。With the development of minimally invasive treatment concept, the application of minimally invasive techniques in acute biliary pancreatitis (ABP) has gradually been favored and widely promoted, but its intervention indications, methods and timing are still controversial. The purpose of this review is to summarize the selection of minimally invasive treatment for ABP, including endoscopic therapy, minimally invasive surgery, puncture drainage and other means, so as to provide reference for clinical practice and application. The condition of ABP is changeable, and relevant examinations should be improved as soon as possible during conservative treatment, early diagnosis and evaluation of the severity of the condition, corresponding minimally invasive treatment for different conditions, individualized plans, and appropriate minimally invasive methods or comprehensive measures should be selected at the right time for treatment.
基金supported by the National Key Technologies Research and Development Program(2021YFF1200602)the National Science Fund for Excellent Overseas Scholars(0401260011)+1 种基金the National Defense Science and Technology Innovation Fund of Chinese Academy of Sciences(c02022088)Tianjin Science and Technology Program(20JCZDJC00810).
文摘Dear Editor,The primary objective of the letter is to emphasize the importance of personalized management of arterial blood pressure(ABP)in the context of off-pump coronary artery bypass grafting(CABG)surgery.Coronary artery disease,a leading global cause of mortality,necessitates a substantial number of cardiac surgeries,with approximately 400,000 CABG operations conducted annually in the United States.Postoperative heart failure(HF)is a common occurrence after CABG surgery,with readmission rates within 30 d due to HF ranging from 12% to 16%.
基金supported by the National Natural Science Foundation of China(32130010).
文摘The phytohormone auxin exerts control over remarkable developmental processes in plants.It moves from cell to cell,resulting in the creation of both extracellular auxin and intracellular auxin,which are recognized by distinct auxin receptors.These two auxin signaling systems govern different auxin responses while working together to regulate plant development.In this review,we outline the latest research advancements in unraveling these auxin signaling pathways,encompassing auxin perception and signaling transductions.We emphasize the interaction between extracellular and intracellular auxin,which contributes to the intricate role of auxin in plant development.
基金Supported by the NSFC(11771087,12171091 and 11831005)。
文摘In this note,we prove a logarithmic Sobolev inequality which holds for compact submanifolds without a boundary in manifolds with asymptotically nonnegative sectional curvature.Like the Michale-Simon Sobolev inequality,this inequality contains a term involving the mean curvature.
文摘【目的】将抗逆相关转录因子ABP9基因导入大豆(Glycine max L.)基因组,并对转化系统条件进行探索,为提高大豆遗传转化效率提供依据。【方法】以农杆菌介导的半种法大豆遗传转化系统为基础,对目的基因进行转化;以健康外植体获得率、抗性丛生芽获得率和抗性芽伸长比率为指标,对转化系统条件进行优化。【结果】共培养时保证充足的光照和氧气,外植体生长情况最好;在共培养或诱导丛生芽培养基中加入600mg·L-1的L-半胱氨酸可以使抗性丛生芽获得率由22.1%提高至32.6%;采用4种植物激素进行正交试验,诱导抗性芽伸长比率最高的激素配比为:6-BA为1.5mg·L-1,GA3为0.75mg·L-1,IAA为0.1mg·L-1,ZT为1.0mg·L-1。【结论】利用优化的方法进行遗传转化研究已获得转基因再生植株,经PCR和DNA测序等分子检测,证明目的基因ABP9已导入并整合到大豆基因组中;转化率为1.33%。
