期刊文献+
共找到342,779篇文章
< 1 2 250 >
每页显示 20 50 100
Transplantation of human neural stem cells repairs neural circuits and restores neurological function in the stroke-injured brain
1
作者 Peipei Wang Peng Liu +7 位作者 Yingying Ding Guirong Zhang Nan Wang Xiaodong Sun Mingyue Li Mo Li Xinjie Bao Xiaowei Chen 《Neural Regeneration Research》 2026年第3期1162-1171,共10页
Exogenous neural stem cell transplantation has become one of the most promising treatment methods for chronic stroke.Recent studies have shown that most ischemia-reperfusion model rats recover spontaneously after inju... Exogenous neural stem cell transplantation has become one of the most promising treatment methods for chronic stroke.Recent studies have shown that most ischemia-reperfusion model rats recover spontaneously after injury,which limits the ability to observe long-term behavioral recovery.Here,we used a severe stroke rat model with 150 minutes of ischemia,which produced severe behavioral deficiencies that persisted at 12 weeks,to study the therapeutic effect of neural stem cells on neural restoration in chronic stroke.Our study showed that stroke model rats treated with human neural stem cells had long-term sustained recovery of motor function,reduced infarction volume,long-term human neural stem cell survival,and improved local inflammatory environment and angiogenesis.We also demonstrated that transplanted human neural stem cells differentiated into mature neurons in vivo,formed stable functional synaptic connections with host neurons,and exhibited the electrophysiological properties of functional mature neurons,indicating that they replaced the damaged host neurons.The findings showed that human fetal-derived neural stem cells had long-term effects for neurological recovery in a model of severe stroke,which suggests that human neural stem cells-based therapy may be effective for repairing damaged neural circuits in stroke patients. 展开更多
关键词 behavioral recovery circuit repair electrophysiological properties functional integration human neural stem cell transplantation infarction volume STROKE synaptic tracing
暂未订购
MET receptor tyrosine kinase promotes the generation of functional synapses in adult cortical circuits
2
作者 Yuehua Cui Xiaokuang Ma +7 位作者 Jing Wei Chang Chen Neha Shakir Hitesch Guirram Zhiyu Dai Trent Anderson Deveroux Ferguson Shenfeng Qiu 《Neural Regeneration Research》 SCIE CAS 2025年第5期1431-1444,共14页
Loss of synapse and functional connectivity in brain circuits is associated with aging and neurodegeneration,however,few molecular mechanisms are known to intrinsically promote synaptogenesis or enhance synapse functi... Loss of synapse and functional connectivity in brain circuits is associated with aging and neurodegeneration,however,few molecular mechanisms are known to intrinsically promote synaptogenesis or enhance synapse function.We have previously shown that MET receptor tyrosine kinase in the developing cortical circuits promotes dendritic growth and dendritic spine morphogenesis.To investigate whether enhancing MET in adult cortex has synapse regenerating potential,we created a knockin mouse line,in which the human MET gene expression and signaling can be turned on in adult(10–12 months)cortical neurons through doxycycline-containing chow.We found that similar to the developing brain,turning on MET signaling in the adult cortex activates small GTPases and increases spine density in prefrontal projection neurons.These findings are further corroborated by increased synaptic activity and transient generation of immature silent synapses.Prolonged MET signaling resulted in an increasedα-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid/N-methyl-Daspartate(AMPA/NMDA)receptor current ratio,indicative of enhanced synaptic function and connectivity.Our data reveal that enhancing MET signaling could be an interventional approach to promote synaptogenesis and preserve functional connectivity in the adult brain.These findings may have implications for regenerative therapy in aging and neurodegeneration conditions. 展开更多
关键词 aging circuit connectivity cortical circuits molecular mechanisms neural regeneration NEURODEGENERATION synapses
暂未订购
Preface to Special Topic on Integrated Circuits, Technologies and Applications 2024
3
作者 Zheng Wang Yan Lu 《Journal of Semiconductors》 2025年第6期6-7,共2页
This Special Topic of the Journal of Semiconductors(JOS)features expanded versions of key articles presented at the 2024 IEEE International Conference on Integrated Circuits Technologies and Applications(ICTA),which w... This Special Topic of the Journal of Semiconductors(JOS)features expanded versions of key articles presented at the 2024 IEEE International Conference on Integrated Circuits Technologies and Applications(ICTA),which was held in Hangzhou,Zhejiang,China,from October 25 to 27,2024. 展开更多
关键词 TECHNOLOGIES IEEE International Conference Integrated circuits Technologies Applications integrated circuits technologies integrated circuits ZHEJIANG expanded versions key articles journal semiconductors APPLICATIONS
在线阅读 下载PDF
CRISPR-Cas systems in DNA functional circuits:Strategies,challenges,prospects
4
作者 Xiaolong Li Changjiang Li +4 位作者 Chaopeng Shi Jiarun Wang Bei Yan Xianjin Xiao Tongbo Wu 《Chinese Chemical Letters》 2025年第7期49-57,共9页
Strand displacement-based DNA circuits have emerged as highly effective tools for molecular computation,serving purposes of amplification or decision-making.They are favored for their inherent occurrence and sensitivi... Strand displacement-based DNA circuits have emerged as highly effective tools for molecular computation,serving purposes of amplification or decision-making.They are favored for their inherent occurrence and sensitivity to external conditions.However,achieving enhanced amplification or decision-making necessitates the incorporation of multiple strands,thereby increasing the risk of contamination.Recent advancements have led to the development of CRISPR-Cas-based DNA circuits.These systems aim to simplify the complexity associated with conventional circuits,mitigate contamination risks,and enable more substantial amplification or decision-making capabilities.Here,the review article centers on current strategies of CRISPR-Cas(Cas9,Cas12a,Cas13a)system-assisted circuits in amplification and decisionmaking,and assesses their tendencies and limitations in amplification circuits and decision-making circuits.Furthermore,we discuss the challenges of CRISPR-Cas in circuits and propose prospects that will contribute to constructing more efficient and diverse CRISPR-Cas-based DNA functional circuits. 展开更多
关键词 CRISPR-Cas DNA circuit AMPLIFICATION DECISION-MAKING
原文传递
Simulation of the non-Hermitian Kitaev chain by electrical circuits
5
作者 Jiali Xu Hao Geng +3 位作者 Abdul Wahab Xiaosen Yang Yuee Xie Yuanping Chen 《Chinese Physics B》 2025年第6期588-595,共8页
We investigate the topological properties of the non-Hermitian Kitaev chain by exploiting the versatility of the circuit.We implement non-reciprocal coupling through a negative impedance converter with current inversi... We investigate the topological properties of the non-Hermitian Kitaev chain by exploiting the versatility of the circuit.We implement non-reciprocal coupling through a negative impedance converter with current inversion(INIC). By conducting impedance measurements between neighboring nodes, we identify both topologically non-trivial and trivial phases within the circuit's admittance band dispersion under open boundary conditions(OBC). Our analysis of complex admittance spectra reveals differences when comparing circuits with periodic boundary conditions(PBC) to those with OBC.Furthermore, we observe Z_(2) skin effects and Majorana zero modes in the topologically non-trivial phases, which are robust against disorders. Notably, the admittance spectra exhibit remarkable sensitivity to the attenuation of the boundary coupling strength. This AC circuit system serves as a promising platform for investigating topological phenomena, opening avenues for the development of functional devices across various application scenarios. 展开更多
关键词 non-Hermitian Kitaev chain non-Hermitian skin effect CIRCUIT
原文传递
Investigation and Research on Students'Learning Ability in Vocational Undergraduate Education:A Case Study of the Integrated Circuits Major at Shenzhen Polytechnic University
6
作者 CHENG Bowen 《Philosophy Study》 2025年第5期269-276,共8页
Vocational undergraduate education has entered a new stage of high-quality development,making the cultivation of students'learning ability a core issue in enhancing talent cultivation quality.This study conducted ... Vocational undergraduate education has entered a new stage of high-quality development,making the cultivation of students'learning ability a core issue in enhancing talent cultivation quality.This study conducted a questionnaire survey with 177 students majoring in integrated circuits at Shenzhen Polytechnic University(SZPU),focusing on six dimensions:self-learning proficiency,academic competence,goal planning,self-discipline,learning initiative,and learning environment.The results indicate that while students possess a solid learning foundation and clear career planning,significant deficiencies exist in the execution of academic plans,self-discipline,and learning initiative.In response to these issues,this study proposes four systematic improvement pathways from the institutional perspective:establishing a closed-loop academic navigation system incorporating“goal-process-feedback”,creating an immersive“virtual-physical integrated”learning environment,implementing a multi-dimensional“cognitive-affective-practical”initiative activation plan,and building a synergistic cultivation mechanism for“self-discipline and core competencies”.The findings aim to provide references for talent cultivation and teaching reform in vocational undergraduate integrated circuit programs. 展开更多
关键词 vocational undergraduate education students'learning ability integrated circuit major
在线阅读 下载PDF
Many-body scars in quantum Heisenberg XY models and analog simulations on superconducting circuits
7
作者 Zexian GUO Jinlou MA +1 位作者 Yu GAO Lei YING 《Journal of Zhejiang University-Science A(Applied Physics & Engineering)》 2025年第9期876-894,共19页
Quantum many-body systems lie at the heart of modern fundamental physics.The study of these systems has revealed a plethora of fascinating phenomena,such as quantum thermalization,many-body localization,and quantum ma... Quantum many-body systems lie at the heart of modern fundamental physics.The study of these systems has revealed a plethora of fascinating phenomena,such as quantum thermalization,many-body localization,and quantum many-body scars.This review provides a comprehensive overview of the recent advances in understanding quantum many-body scars and non-ergodic dynamics in quantum systems on superconducting-circuit platforms,ranging from theoretical mechanisms and effective models to experimental observations. 展开更多
关键词 Quantum many-body scars Quantum chaos Quantum simulation Superconducting circuits
原文传递
Fault-Tolerant Control of Current Measurement Circuits for Three-Phase Grid-Connected Inverters
8
作者 Fatma Ben Youssef Ahlem Ben Youssef +1 位作者 Mohamed Naoui Lassaad Sbita 《Journal of Dynamics, Monitoring and Diagnostics》 2025年第4期308-317,共10页
Three-phase grid-connected inverters(GCIs)are essential components in distributed generation systems,where the accuracy of current measurement circuits is fundamental for reliable closed-loop operation.Nevertheless,th... Three-phase grid-connected inverters(GCIs)are essential components in distributed generation systems,where the accuracy of current measurement circuits is fundamental for reliable closed-loop operation.Nevertheless,the presence of a DC offset in the measured current can disrupt the regulation of grid currents and significantly degrade system performance.In this work,a fault-tolerant control approach is introduced to counteract the impact of such offset faults through a dedicated current compensation mechanism.The proposed solution is built around two main stages:(i)detecting and isolating DC offset faults that may appear in one or multiple phases of the measured grid currents,and(ii)estimating the fault magnitude and reconstructing the corrected current signal.The offset magnitude is obtained analytically by examining the grid current projected onto the synchronous d-axis at the grid angular frequency,eliminating the need for any additional sensing hardware.Simulation and experimental investigations conducted under several fault scenarios confirm the robustness of the proposed strategy and highlight significant improvements in detection speed and diagnostic accuracy. 展开更多
关键词 fault detection grid-connected inverter fault isolation fault-tolerant control sensing circuit
在线阅读 下载PDF
Research on Optimization Strategies for Signal Integrity of High-Speed Digital Circuits in Electronic Information Engineering
9
作者 Yiming Li 《Journal of Electronic Research and Application》 2025年第5期304-309,共6页
With the rapid development of electronic information engineering,high-speed digital circuits have been increasingly widely applied in various fields.In high-speed digital circuits,signal integrity is prone to interfer... With the rapid development of electronic information engineering,high-speed digital circuits have been increasingly widely applied in various fields.In high-speed digital circuits,signal integrity is prone to interference from various external factors,leading to issues such as signal distortion or degradation of system performance.Based on this,this paper conducts research on the optimization strategies for signal integrity of high-speed digital circuits in electronic information engineering.It deeply analyzes the importance of high-speed digital circuits,elaborates on the challenges they face and the specific manifestations of signal integrity issues,and proposes a series of optimization strategies in electronic information engineering.The aim is to improve the signal integrity of highspeed digital circuits and provide theoretical support and practical guidance for the development of related fields. 展开更多
关键词 High-speed digital circuits Signal integrity Electronic information engineering Optimization strategies
在线阅读 下载PDF
A low-noise and high-stability DC source for superconducting quantum circuits
10
作者 Daxiong Sun Jiawei Zhang +16 位作者 Peisheng Huang Yubin Zhang Zechen Guo Tingjin Chen Rui Wang Xuandong Sun Jiajian Zhang Wenhui Huang Jiawei Qiu Ji Chu Ziyu Tao Weijie Guo Xiayu Linpeng Ji Jiang Jingjing Niu Youpeng Zhong Dapeng Yu 《Chinese Physics B》 2025年第9期48-55,共8页
With the rapid scaling of superconducting quantum processors,electronic control systems relying on commercial off-the-shelf instruments face critical bottlenecks in signal density,power consumption,and crosstalk mitig... With the rapid scaling of superconducting quantum processors,electronic control systems relying on commercial off-the-shelf instruments face critical bottlenecks in signal density,power consumption,and crosstalk mitigation.Here we present a custom dual-channel direct current(DC)source module(QPower)dedicated to large-scale superconducting quantum processors.The module delivers a voltage range of±7 V with 200 m A maximum current per channel,while achieving the following key performance benchmarks:noise spectral density of√Hz at 10 k Hz,output ripple<500μV_(pp)within 20 MHz bandwidth,and long-term voltage drift<5μVpp over 12 hours.Integrated into the control electronics of a 66-qubit quantum processor,QPower enables qubit coherence time of T_(1)=87.6μs and Ramsey dephasing time of T_(2)=5.1μs,with qubit resonance frequency drift constrained to±40 k Hz during 12-hour operation.This modular design is compact in size and efficient in energy consumption,providing a scalable DC source solution for intermediate-scale quantum processors with stringent noise and stability requirements,with potential extensions to other quantum hardware platforms and precision measurement systems. 展开更多
关键词 superconducting quantum circuits superconducting qubit low noise DC source
原文传递
Single-Molecule Detection by Silicon-based Photonic Integrated Circuits Chip
11
作者 Dong Li Chengda Pan +7 位作者 Qiannan Huang Xiao Li Yan Zou Pengxiao Lv Xiujun Zheng Sarp Kerman Chunrui Hu Chang Chen 《Chinese Journal of Chemical Physics》 2025年第2期149-155,I0001,I0039,共9页
The single-molecule detection tech-nique plays a pivotal role in elucidat-ing the fundamental mechanisms of various scientific processes at the molecular level,and holds essential im-portance in multiple fields includ... The single-molecule detection tech-nique plays a pivotal role in elucidat-ing the fundamental mechanisms of various scientific processes at the molecular level,and holds essential im-portance in multiple fields including physics,biology,and chemistry.Re-cently,single-molecule detection has garnered increasing attention owing to its practical utility in medical diagno-sis,primarily due to its exceptional sensitivity and the minimal sample volume required for analysis.However,the conventional single-molecule technique,represented by total internal reflection microscopy,faces challenges such as sophisticated operation procedures and limited detection throughput,thereby impeding its broader application.To address these limitations,we have demonstrated single-molecule detection using an integrated silicon photonic chip,of-fering a cost-effective and user-friendly alternative.By employing basic optics,we efficiently introduce the excitation source for single-molecule fluorescence by harnessing the strong evanescent field of high refractive-index waveguides.Subsequently,fluorescence signals are collected using basic optics comprising a water-immersion objective,relay optics,and a digi-tal camera.Our results highlight a low-cost,high-throughput single-molecule technique achieved through the integrated silicon photonic chip.This innovative approach is promised to facilitate the widespread adoption of single-molecule fluorescence in medical diagnosis. 展开更多
关键词 Single-molecule fluorescence Silicon photonics Photonic integrated circuit To-tal internal reflection fluorescence microscopy
在线阅读 下载PDF
Two-Dimensional Materials,the Ultimate Solution for Future Electronics and Very-Large-Scale Integrated Circuits
12
作者 Laixiang Qin Li Wang 《Nano-Micro Letters》 2025年第10期600-652,共53页
The relentless down-scaling of electronics grands the modern integrated circuits(ICs)with the high speed,low power dissipation and low cost,fulfilling diverse demands of modern life.Whereas,with the semiconductor indu... The relentless down-scaling of electronics grands the modern integrated circuits(ICs)with the high speed,low power dissipation and low cost,fulfilling diverse demands of modern life.Whereas,with the semiconductor industry entering into sub-10 nm technology nodes,degrading device performance and increasing power consumption give rise to insurmountable roadblocks confronted by modern ICs that need to be conquered to sustain the Moore law's life.Bulk semiconductors like prevalent Si are plagued by seriously degraded carrier mobility as thickness thinning down to sub-5 nm,which is imperative to maintain sufficient gate electrostatic controllability to combat the increasingly degraded short channel effects.Nowadays,the emergence of two-dimensional(2D)materials opens up new gateway to eschew the hurdles laid in front of the scaling trend of modern IC,mainly ascribed to their ultimately atomic thickness,capability to maintain carrier mobility with thickness thinning down,dangling-bonds free surface,wide bandgaps tunability and feasibility to constitute diverse heterostructures.Blossoming breakthroughs in discrete electronic device,such as contact engineering,dielectric integration and vigorous channel-length scaling,or large circuits arrays,as boosted yields,improved variations and full-functioned processor fabrication,based on 2D materials have been achieved nowadays,facilitating 2D materials to step under the spotlight of IC industry to be treated as the most potential future successor or complementary counterpart of incumbent Si to further sustain the down-scaling of modern IC. 展开更多
关键词 2D materials Short channel effects Integrated circuits Degraded carrier mobility Moore's law
在线阅读 下载PDF
C反应蛋白/白蛋白比值与D-二聚体联合检测对妊娠合并急性胰腺炎病情严重程度的预测价值
13
作者 刘英男 严丽梅 《中国医科大学学报》 北大核心 2026年第1期75-79,共5页
目的探讨血清C反应蛋白/白蛋白比值(CAR)、D-二聚体及二者联合检测预测妊娠合并急性胰腺炎(APIP)病情严重程度的价值。方法收集2021年1月至2023年12月间我院APIP患者及同期分娩的正常妊娠者(健康对照组)的临床资料。根据APIP病情严重程... 目的探讨血清C反应蛋白/白蛋白比值(CAR)、D-二聚体及二者联合检测预测妊娠合并急性胰腺炎(APIP)病情严重程度的价值。方法收集2021年1月至2023年12月间我院APIP患者及同期分娩的正常妊娠者(健康对照组)的临床资料。根据APIP病情严重程度将患者分为非重症组、重症组;根据病因分为胆源型组、高脂血症型组、特发型组。用logistic回归分析影响APIP病情严重程度的危险因素及其诊断效能。结果CAR、D-二聚体是影响APIP病情严重程度的独立危险因素。CAR和D-二聚体联合检测受试者操作特征曲线下面积最大,且灵敏度、特异度等诊断效能均优于单独检测。结论CAR及D-二聚体是APIP病情严重程度的独立危险因素,且二者联合检测可作为APIP病情严重程度的良好预测指标。 展开更多
关键词 妊娠合并急性胰腺炎 C反应蛋白/白蛋白比值 D-二聚体 联合预测
暂未订购
Enhancing Safety in Electric Vehicles:Multi-Tiered Fault Detection for Micro Short Circuits and Aging in Battery Modules
14
作者 Yi-Feng Luo Jyuan-FongYen Wen-Cheng Su 《Computer Modeling in Engineering & Sciences》 2025年第3期3069-3087,共19页
This article proposes a multi-tiered fault detection system for series-connected lithium-ion battery modules.Improper use of batteries can lead to electrolyte decomposition,resulting in the formation of lithium dendri... This article proposes a multi-tiered fault detection system for series-connected lithium-ion battery modules.Improper use of batteries can lead to electrolyte decomposition,resulting in the formation of lithium dendrites.These dendrites may pierce the separator,leading to the failure of the insulation layer between electrodes and causing micro short circuits.When a micro short circuit occurs,the electrolyte typically undergoes exothermic reactions,leading to thermal runaway and posing a safety risk to users.Relying solely on temperature-based judgment mechanisms within the battery management system often results in delayed intervention.To address this issue,the article develops a multi-tiered fault detection algorithm for series-connected lithium-ion batteries.This algorithm can effectively diagnose micro short circuits,aging,and normal batteries using minimal battery data,thereby improving diagnostic accuracy and enhancing the flexibility of fault detection.Simulations and experiments conducted under various levels of micro short circuits validate the effectiveness of the algorithm,demonstrating its ability to distinguish between short-circuited,aged,and normal batteries under different conditions.This technology can be applied to electric vehicles and energy storage systems,enabling early warnings to ensure safety and prevent thermal runaway. 展开更多
关键词 Multi-tiered fault detection micro short circuits(MSC) battery management system(BMS) lithiumion batteries electric vehicles(EV) energy storage systems(ESS)
在线阅读 下载PDF
复合材料C型柔性杆准静态卷收力学性能分析及优化设计
15
作者 叶红玲 王星运 +3 位作者 宋修营 金辰昊男 孙天峰 武海生 《北京工业大学学报》 北大核心 2026年第1期13-21,共9页
复合材料C型柔性杆展开结构(C型杆)由于其质量轻、结构简单和折展比高等特点,已广泛应用于宇航空间领域。该文以C型杆为研究对象,采用显式动力学分析方法,对其进行准静态仿真分析,研究卷收过程的力学性能,并提出了一种复合材料C型杆的... 复合材料C型柔性杆展开结构(C型杆)由于其质量轻、结构简单和折展比高等特点,已广泛应用于宇航空间领域。该文以C型杆为研究对象,采用显式动力学分析方法,对其进行准静态仿真分析,研究卷收过程的力学性能,并提出了一种复合材料C型杆的优化设计方法。研究了C型杆截面半径、截面圆心角、杆长等几何参数对卷收最大应变能、一阶固有频率、最大应力等力学性能的影响规律。基于响应面方法,建立了以结构应变能和一阶固有频率最大为目标,以最大应力为约束,以几何参数为设计变量的多目标优化模型,并采用遗传算法进行求解,获得可行解分布和最优解,研究结果对于提高空间展开结构的力学性能和优化设计具有重要的理论意义。 展开更多
关键词 复合材料 C型杆 准静态卷收 力学性能 响应面法 多目标优化
在线阅读 下载PDF
知识图谱驱动的C++课程BOPPPS+ADCD教学模式探索
16
作者 王云艳 《计算机教育》 2026年第1期233-239,共7页
针对传统教学中自主学习和迁移学习不足、高阶计算思维培养不足、评价体系动态反馈不足等问题,提出知识图谱驱动的BOPPPS+ADCD线上线下混合教学模式,以C++程序设计课程为例,阐述如何通过知识图谱引领学生自主学习,并在BOPPPS参与式教学... 针对传统教学中自主学习和迁移学习不足、高阶计算思维培养不足、评价体系动态反馈不足等问题,提出知识图谱驱动的BOPPPS+ADCD线上线下混合教学模式,以C++程序设计课程为例,阐述如何通过知识图谱引领学生自主学习,并在BOPPPS参与式教学环节融入ADCD四阶段强化高阶计算思维训练,构建“教学—评价—改进”智慧评价的动态教学闭环以实现教学动态优化,最后说明教学实践效果。 展开更多
关键词 C++程序设计 知识图谱 BOPPPS+ADCD教学模式 智慧评价
在线阅读 下载PDF
颈脑一体化超声斑块回声特征联合血浆CRP、LDL-C水平对动脉粥样硬化斑块不稳定性的诊断价值
17
作者 曾红英 颜媛 徐敏 《影像科学与光化学》 2026年第1期110-116,共7页
目的:评估颈脑一体化超声斑块回声特征联合血浆CRP和LDL-C水平在动脉粥样硬化斑块不稳定性诊断中的临床价值。方法:本研究纳入2021年1月至2023年6月期间的264名动脉粥样硬化患者。所有患者接受颈脑一体化超声检查,评估斑块回声特征,并... 目的:评估颈脑一体化超声斑块回声特征联合血浆CRP和LDL-C水平在动脉粥样硬化斑块不稳定性诊断中的临床价值。方法:本研究纳入2021年1月至2023年6月期间的264名动脉粥样硬化患者。所有患者接受颈脑一体化超声检查,评估斑块回声特征,并通过免疫比浊法和酶法检测血浆CRP和LDL-C水平。斑块稳定性通过超声造影和CT血管成像评估,并以急性心肌梗死或脑卒中发生作为临床标准。采用多因素Logistic回归分析评估颈脑一体化超声斑块回声特征、CRP和LDL-C与斑块不稳定性之间的关系,同时使用ROC曲线评估各项检测方法的诊断性能。结果:低回声斑块126例(47.7%),混合回声斑块98例(37.1%),高回声斑块40例(15.2%)。斑块不稳定的患者有98例(37.1%)。单独使用斑块回声特征的敏感度为85.4%,特异度为77.2%;CRP的敏感度为71.3%,特异度为68.5%;LDL-C的敏感度为60.1%,特异度为64.8%。多因素Logistic回归分析显示,颈脑一体化超声斑块回声特征(OR=3.62,95%CI:2.45~5.31,P<0.001)、CRP(OR=2.48,95%CI:1.56~3.97,P=0.002)和LDL-C(OR=1.89,95%CI:1.22~2.94,P=0.015)为斑块不稳定性的独立预测因素。ROC曲线分析显示,联合诊断模型的AUC为0.91(95%CI:0.88~0.94),明显高于单项指标(斑块回声特征:AUC=0.82,95%CI:0.77~0.87;CRP:AUC=0.81,95%CI:0.76~0.86;LDL-C:AUC=0.80,95%CI:0.74~0.85)。联合模型的敏感度为91.2%,特异度为82.6%。结论:颈脑一体化超声斑块回声特征联合CRP和LDL-C水平,在动脉粥样硬化斑块不稳定性诊断中表现出较高的诊断效能,能有效提高早期识别能力,为临床提供高效筛查手段。 展开更多
关键词 颈脑一体化超声 斑块回声特征 C反应蛋白 低密度脂蛋白胆固醇 动脉粥样硬化 斑块不稳定性 诊断价值
暂未订购
基于无人机的支挡结构三维重建及全场位移监测
18
作者 朱前坤 周叙霖 杜永峰 《工程力学》 北大核心 2026年第1期230-239,共10页
支挡结构的位移监测可以为评估其工作状态、病害检测、灾害预警提供分析依据。为解决传统方法监测效率低、成本较高、危险系数大等缺点,该文提出基于无人机的支挡结构三维重建及全场位移监测方法。采用无人机拍摄支挡结构表面多视角图像... 支挡结构的位移监测可以为评估其工作状态、病害检测、灾害预警提供分析依据。为解决传统方法监测效率低、成本较高、危险系数大等缺点,该文提出基于无人机的支挡结构三维重建及全场位移监测方法。采用无人机拍摄支挡结构表面多视角图像,利用Colmap算法计算每张照片所对应的位姿并计算三维稀疏点云;利用基于深度学习的Patchmatchnet算法进行三维稠密点云重建;将不同时期的两期点云配准后利用M3C2算法进行点云对比,获得支挡结构的全场位移数据及位移云图。为验证该方法的准确性,在验证试验中应用了基于物理的图形模型(Physics-Based Graphical Model,PBGM),建立目标结构的Abaqus有限元模型,在有限元模型中施加荷载,计算模型的响应;将得到的变形后模型与未变形模型导出至Blender虚拟空间中,进行纹理贴图后设置无人机飞行航线,将3种工况下由该方法计算得到的全场位移与有限元计算得到的位移进行对比,验证了该方法在PBGM模型试验中,模型长度、宽度及位移监测方向上的误差均小于1 cm。在工程应用方面,将该方法应用于兰州市某框架复合锚杆土钉墙,成功监测到了其全场位移,证明该方法适用于人员不易到达、较为陡峭、危险性较高的支挡结构位移监测,可为支挡结构的安全性和稳定性评估提供依据。 展开更多
关键词 深度学习 位移监测 PBGM 三维重建 支挡结构 M3C2
在线阅读 下载PDF
固碳轻质土制备方法与物理力学性能研究
19
作者 刘松玉 张翔 +3 位作者 蔡光华 袁振扬 安景峰 陈光伟 《岩土工程学报》 北大核心 2026年第1期15-23,共9页
为减少碳排放、探寻岩土工程的二氧化碳(CO_(2))利用技术,基于氧化镁(MgO)碳化固化原理,提出了一种固碳轻质土(carbon sequestration lightweight soil,C-LS)原理,该原理采用MgO和渣土替代水泥作为固化材料、CO_(2)替代空气发泡,将MgO... 为减少碳排放、探寻岩土工程的二氧化碳(CO_(2))利用技术,基于氧化镁(MgO)碳化固化原理,提出了一种固碳轻质土(carbon sequestration lightweight soil,C-LS)原理,该原理采用MgO和渣土替代水泥作为固化材料、CO_(2)替代空气发泡,将MgO、粉质黏土、水和CO_(2)泡沫按一定比例混合后形成密度<1 g/cm3的C-LS。通过无侧限抗压强度、扫描电镜和热重等宏微观试验,研究了不同MgO掺量、设计湿密度、水固比与碳化养护条件对C-LS的流值、凝结时间、干密度、强度、碳化产物及固碳能力的影响规律。结果表明:随MgO掺量和湿密度增加,C-LS流值和凝结时间减小,抗压强度提高,同时其固碳量提高。确定了C-LS的最优配比,在自然养护下,其28 d强度可满足高速公路路堤填筑和其它填筑材料要求,在外部加速碳化条件下,C-LS强度可进一步提高。根据C-LS强度与碳化产物产量及固碳量的内在联系,研究揭示了C-LS强度形成微观机理。C-LS技术能大量消耗CO_(2)和工程渣土,为岩土工程固碳利用提供了崭新的技术途径。 展开更多
关键词 C-LS MGO 二氧化碳泡沫 制备方法 物理力学特性
原文传递
基于磁场梯度张量的变压器绕组短路力及形变分析
20
作者 杨帆 高三策 +2 位作者 赵轶 王嘉玮 王鹏博 《电工技术学报》 北大核心 2026年第1期14-25,共12页
该文提出一种基于磁场梯度张量的电磁力计算方法,用于分析变压器绕组中的电磁力和形变。首先,分析绕组中磁场一阶张量和二阶张量的分布特征,探讨张量分布与电磁力之间的内在关系和相互作用机制。然后,基于该关系,定义一个新的张量G,命... 该文提出一种基于磁场梯度张量的电磁力计算方法,用于分析变压器绕组中的电磁力和形变。首先,分析绕组中磁场一阶张量和二阶张量的分布特征,探讨张量分布与电磁力之间的内在关系和相互作用机制。然后,基于该关系,定义一个新的张量G,命名为磁场梯度应力张量,通过其进一步计算了三维坐标上每个方向的电磁力密度。最后,搭建一个配备磁场、应力和应变传感器的35kV单相油浸式缩比变压器试验平台,通过短路试验结果与3D模型的计算对比,验证了该方法的有效性。研究表明,通过磁场梯度法计算得到的电磁力和形变结果与试验结果的最大误差分别为2.4%和2.7%,满足工程实际需求。该方法简化了电磁力的计算过程,同时保持了较高的精度,可为绕组磁-热-力耦合形变分析奠定良好基础,提高变压器在短路条件下的稳定性和安全性。 展开更多
关键词 变压器 磁场梯度 电磁力 短路故障 形变分析
在线阅读 下载PDF
上一页 1 2 250 下一页 到第
使用帮助 返回顶部