In general,bioassay-guided fractionation and isolation of bioactive constituents from botanical materials frequently ended up with the reward of a single compound.However,botanical materials typically exert their ther...In general,bioassay-guided fractionation and isolation of bioactive constituents from botanical materials frequently ended up with the reward of a single compound.However,botanical materials typically exert their therapeutic actions through multi-pathway effects due to the intrinsic complex nature of chemical constituents.In addition,the content of bioactive compounds in botanical materials is largely dependent on humidity,temperature,soil,especially geographical origins,from which rapid and accurate identification of plant materials is pressingly needed.These long-standing obstacles collectively impede the deep exploi-tation and application of these versatile natural sources.To address the challenges,a new paradigm inte-grating biogravimetric analyses and machine learning-driven origin classification(BAMLOC)was developed.The biogravimetric analyses are based on absolute qHNMR quantification and in vivo zebrafish model-assisted activity index calculation,by which bioactive substance groups jointly responsible for the bioactivities in all fractions are pinpointed before any isolation effort.To differentiate origin-different botanical materials varying in the content of bioactive substance groups,principal component analysis,linear discriminant analysis,and hierarchical cluster analysis in conjunction with supervised support vector machine are employed to classify and predict production areas based on the detection of volatile organic compounds by E-nose and gas chromatography-mass spectrometry(GC-MS).Expanding BAMLOC to Codonopsis Radix enables the identification of polyacetylenes and pyrrolidine alkaloids as the bioactive substance group for immune restoration effect and accurately determines the origins of plants.This study advances the toolbox for the discovery of bioactive compounds from complex mixtures and lays a more definitive foundation for the in-depth utilization of botanical materials.展开更多
The reliability and availability of the reactor protection system (RPS) can be improved by using M out of N judg- ment system. By analyzing two quantitative indicators, the rate of refusal to operate and mal-operati...The reliability and availability of the reactor protection system (RPS) can be improved by using M out of N judg- ment system. By analyzing two quantitative indicators, the rate of refusal to operate and mal-operation rate, a strict math- ematical formula and an approximate calculation are stated. The differences of a series of judgment systems are discussed on condition that the unsafe failure probability and the security failure probability are both 0.1. Based on given parameters (A, B,P, Q): A is upper limit of the refusal rate for the RPS, B is upper limit of the real-operation rate, P and Q are basic protection unit rates corresponding to refusal rate and mal-operation rate, respectively. According to these parameters, the values of N and M can be solved.展开更多
Although the quantification and valuation of ecosystem services have been studied for a long time, few studies have specifi- cally focused on the quantification of tradeoffs between ecosystem services and tradeoff hot...Although the quantification and valuation of ecosystem services have been studied for a long time, few studies have specifi- cally focused on the quantification of tradeoffs between ecosystem services and tradeoff hotspots, Based on previous studies of ecosys- tem service assessment, we proposed a feasible method to analyze the tradeoffs between ecosystem services, including determination of their relationship, quantification of tradeoffs, and identification of tradeoff hotspots. Potential influencing factors were then further ana- lyzed. The Yanhe Basin in the Loess Plateau was selected as an example to demonstrate the application process. Firstly, the amounts of net primary production (NPP) and water yield (WY) in 2000 and 2008 were estimated by using biophysical models, Secondly, correla- tion analysis was used to indicate the tradeoffs between NPP and WY. Thirdly, tradeoff index (TINpp/wy) was established to quantify the extent of tradeoffs between NPP and WY, and the average value of TINpp/wy is 24.4 g/(mm·m2) for the Yanhe Basin between 2000 and 2008. Finally, the tradeoff hotspots were identified. The results indicated that the area of lowest tradeoff index concentrated in the mid- dle part of the Yanhe Basin and marginal areas of the southern basin. Map overlapping was used for preliminary analysis to seek poten- tial influencing factors, and the results showed that shrub was the best suited for growing in the Yanhe Basin, but also was a potential irtfluencing factor for formulatiort of the tradeoff hotspots. The concept of tradeoff index could also be used to quantify the degree of synergy between different ecosystem services. The method to identify the tradeoff hotspots could help us to narrow the scope of study area for further research on the relationship among ecosystem services and concentrate on the potential factors for formation of tradeoff between ecosystem services, enhance the capacity to maintain the sustainability of ecosystem.展开更多
Due to the increasing demand for security, the development of intelligent surveillance systems has attracted considerable attention in recent years. This study aims to develop a system that is able to identify whether...Due to the increasing demand for security, the development of intelligent surveillance systems has attracted considerable attention in recent years. This study aims to develop a system that is able to identify whether or not the people need help in a public place. Different from previous work, our work considers not only the behaviors of the target person but also the interaction between him and nearby people. In the paper, we propose an event alarm system which can detect the human behaviors and recognize the happening event through integrating the results generated from the single and group behavior analysis. Several new effective features are proposed in the study. Besides, a mechanism capable of extracting one-to-one and multiple-to-one relations is also developed. Experimental results show that the proposed approach can correctly detect human behaviors and provide the alarm messages when emergency events occur.展开更多
A combined cluster and regression analysis were performed for the first time to identify rainfall threshold that triggers landslide events in Amboori, Kerala, India. Amboori is a tropical area that is highly vulnerabl...A combined cluster and regression analysis were performed for the first time to identify rainfall threshold that triggers landslide events in Amboori, Kerala, India. Amboori is a tropical area that is highly vulnerable to landslides. The 2, 3, and 5-day antecedent rainfall data versus daily rainfall was clustered to identify a cluster of critical events that could potentially trigger landslides. Further, the cluster of critical events was utilized for regression analysis to develop the threshold equations. The 5-day antecedent(xvariable) vs. daily rainfall(y-variable) provided the best fit to the data with a threshold equation of y = 80.7-0.1981 x. The intercept of the equation indicates that if the 5-day antecedent rainfall is zero, the minimum daily rainfall needed to trigger the landslide in the Amboori region would be 80.7 mm. The negative coefficient of the antecedent rainfall indicates that when the cumulative antecedent rainfall increases, the amount of daily rainfall required to trigger monsoon landslide decreases. The coefficient value indicates that the contribution of the 5-day antecedent rainfall is~20% to the landslide trigger threshold. The slope stability analysis carried out for the area, using Probabilistic Infinite Slope Analysis Model(PISA-m), was utilized to identify the areas vulnerable to landslide in the region. The locations in the area where past landslides have occurred demonstrate lower Factors of Safety(FS) in the slope stability analysis. Thus, rainfall threshold analysis together with the FS values from slope stability can be suitable for developing a simple, cost-effective, and comprehensive early-warning system for shallow landslides in Amboori and similar regions.展开更多
By using emergy analysis theory and methods,we conduct quantitative analysis on the input and output of emergy,and sustainable development of agro-ecological system in Poyang Lake Area.The results show that compared w...By using emergy analysis theory and methods,we conduct quantitative analysis on the input and output of emergy,and sustainable development of agro-ecological system in Poyang Lake Area.The results show that compared with the national average,the environmental loading ratio is relatively low in this area;the net emergy yield rate is high;the sustainable development ability is strong.Finally according to the results of emergy analysis,corresponding countermeasures are put forward as follows:develop agriculture based on the existing rich natural resources;increase technological inputs;develop circular agriculture;promote sustainable agricultural development.展开更多
This study used Ecopath model of the Jiaozhou Bay as an example to evaluate the effect of stomach sample size of three fish species on the projection of this model. The derived ecosystem indices were classified into t...This study used Ecopath model of the Jiaozhou Bay as an example to evaluate the effect of stomach sample size of three fish species on the projection of this model. The derived ecosystem indices were classified into three categories:(1) direct indices, like the trophic level of species, influenced by stomach sample size directly;(2)indirect indices, like ecology efficiency(EE) of invertebrates, influenced by the multiple prey-predator relationships;and(3) systemic indices, like total system throughout(TST), describing the status of the whole ecosystem. The influences of different stomach sample sizes on these indices were evaluated. The results suggest that systemic indices of the ecosystem model were robust to stomach sample sizes, whereas specific indices related to species were indicated to be with low accuracy and precision when stomach samples were insufficient.The indices became more uncertain when the stomach sample sizes varied for more species. This study enhances the understanding of how the quality of diet composition data influences ecosystem modeling outputs. The results can also guide the design of stomach content analysis for developing ecosystem models.展开更多
Aiming at the characteristics of multi-stage and(extremely)small samples of the identification problem of key effectiveness indexes of weapon equipment system-of-systems(WESoS),a Bayesian intelligent identification an...Aiming at the characteristics of multi-stage and(extremely)small samples of the identification problem of key effectiveness indexes of weapon equipment system-of-systems(WESoS),a Bayesian intelligent identification and inference model for system effectiveness assessment indexes based on dynamic grey incidence is proposed.The method uses multi-layer Bayesian techniques,makes full use of historical statistics and empirical information,and determines the Bayesian estima-tion of the incidence degree of indexes,which effectively solves the difficulties of small sample size of effectiveness indexes and difficulty in obtaining incidence rules between indexes.Sec-ondly,The method quantifies the incidence relationship between evaluation indexes and combat effectiveness based on Bayesian posterior grey incidence,and then identifies key system effec-tiveness evaluation indexes.Finally,the proposed method is applied to a case of screening key effectiveness indexes of a missile defensive system,and the analysis results show that the proposed method can fuse multi-moment information and extract multi-stage key indexes,and has good data extraction capability in the case of small samples.展开更多
Under investigation in this paper is a relativistic Toda lattice system with one perturbation parameterαabbreviated as RTLαsystem by Suris,which may describe the motions of particles in lattices interacting through ...Under investigation in this paper is a relativistic Toda lattice system with one perturbation parameterαabbreviated as RTLαsystem by Suris,which may describe the motions of particles in lattices interacting through an exponential interaction force.First of all,an integrable lattice hierarchy associated with an RTLαsystem is constructed,from which some relevant integrable properties such as Hamiltonian structures,Liouville integrability and conservation laws are investigated.Secondly,the discrete generalized(m,2 N-m)-fold Darboux transformation is constructed to derive multi-soliton solutions,higher-order rational and semirational solutions,and their mixed solutions of an RTLαsystem.The soliton elastic interactions and details of rational solutions are analyzed via the graphics and asymptotic analysis.Finally,soliton dynamical evolutions are investigated via numerical simulations,showing that a small noise has very little effect on the soliton propagation.These results may provide new insight into nonlinear lattice dynamics described by RTLαsystem.展开更多
Photometric observations of AH Cnc, a W UMa-type system in the open cluster M67, were car- fled out by using the 50BIN telescope. About 100h of time-series/3- and V-band data were taken, based on which eight new times...Photometric observations of AH Cnc, a W UMa-type system in the open cluster M67, were car- fled out by using the 50BIN telescope. About 100h of time-series/3- and V-band data were taken, based on which eight new times of light minima were determined. By applying the Wilson-Devinney method, the light curves were modeled and a revised photometric solution of the binary system was derived. We con- firmed that AH Cnc is a deep contact (f = 51%), low mass-ratio (q - 0.156) system. Adopting the distance modulus derived from study of the host cluster, we have re-calculated the physical parameters of the binary system, namely the masses and radii. The masses and radii of the two components were estimated to be respectively 1.188(4-0.061) Me, 1.332(4-0.063) RQ for the primary component and 0.185(4-0.032) Me, 0.592(4-0.051) Re for the secondary. By adding the newly derived minimum timings to all the available data, the period variations of AH Cnc were studied. This shows that the orbital period of the binary is con- tinuously increasing at a rate of dp/dt = 4.29 x 10-10 d yr-1. In addition to the long-term period increase, a cyclic variation with a period of 35.26 yr was determined, which could be attributed to an unresolved tertiary component of the system.展开更多
The article analyses several key issues which restrict the effectiveness of fund project peer review work. It analyses the evaluating theory and matter-element theory to access the expert anti-evaluation model, and al...The article analyses several key issues which restrict the effectiveness of fund project peer review work. It analyses the evaluating theory and matter-element theory to access the expert anti-evaluation model, and also studies the expert anti-evaluation index system to support the anti-evaluation method. The practical basis is the true score data of the experts which is collected from the actual anti-evaluation in Liaoning province science and technology fund project peer review system. With the practical experience of the actual project, we prove that the expert index system anti-evaluation model and expert anti-evaluation method can improve the fund project peer review work and play a positive role for the peer review work and also make the review work more scientific and more rational.展开更多
A model for repairable standby parallel system consisting of two identical components with common cause failure(CCF)and human error is introduced in this article by a semigroup approach.The stability of the system is ...A model for repairable standby parallel system consisting of two identical components with common cause failure(CCF)and human error is introduced in this article by a semigroup approach.The stability of the system is verified by the pure analysis technique,the co-final related theory and functional analysis method.It is discussed that four different reliability indices of the studied model are consistent with each other both analytically and numerically.The simulations and comparisons demonstrate the validity of the proposed technique.展开更多
In this study,the relationship between the subsystems of Asian summer monsoon is analyzed using U.S.National Centers for Environmental Protection/National Center for Atmospheric Research reanalysis and Climate Predict...In this study,the relationship between the subsystems of Asian summer monsoon is analyzed using U.S.National Centers for Environmental Protection/National Center for Atmospheric Research reanalysis and Climate Prediction Center Merged Analysis of Precipitation monthly mean precipitation data.The results showed that there is significant correlation between the subsystems of Asian summer monsoon.The changes of intensity over the same period show that weak large-scale Asian monsoon,Southeast Asia monsoon and South Asian monsoon are associated with strong East Asian monsoon and decreasing rainfall in related areas.And when the large-scale Asian monsoon is strong,Southeast Asia and South Asia monsoons will be strong and precipitation will increase.While the Southeast Asia monsoon is strong,the South Asia monsoon is weak and the rainfall of South Asia is decreasing,and vice versa.The various subsystems are significantly correlated for all periods of intensity changes.展开更多
Objective To establish a scientific,reliable,objective,and effective clinical comprehensive evaluation system for drugs centralized bidding procurement by government,and to conduct reliability and validity test and em...Objective To establish a scientific,reliable,objective,and effective clinical comprehensive evaluation system for drugs centralized bidding procurement by government,and to conduct reliability and validity test and empirical analysis of the evaluation index system through simulated measurement.Methods Literature research method was used to select comprehensive evaluation indicators for drugs centralized bidding procurement.Then,Dephi method was applied to screen the final evaluation indicators,and the weight of the indicators was determined using analytic hierarchy process.Results and Conclusion The final clinical efficacy evaluation index system for drugs centralized bidding procurement includes 5 primary indicators and 13 secondary indicators.The experts authority coefficient in this study is high,and their opinions relatively coincide.Through the empirical research,the reliability and structural validity of the indicator system is good.This indicator system enriches methods and tools for scientifically evaluating the clinical efficacy of drugs centralized bidding procurement.展开更多
Objective To quantitatively analyze the policy of centralized drug procurement centralized drug procurement in order to provide reference for the subsequent policy formulation and improvement.Methods Text mining metho...Objective To quantitatively analyze the policy of centralized drug procurement centralized drug procurement in order to provide reference for the subsequent policy formulation and improvement.Methods Text mining method was used to process 15 centralized drugs procurement policies issued at the national level during 2015-2022,and a PMC index evaluation model of centralized drug procurement policies was established.Then,15 centralized drug procurement policies were quantitatively analyzed from the overall and comparative perspective through an evaluation model.Results and Conclusion The average PMC index of 15 centralized drug procurement policies was 6.95,which was acceptable on the whole.Among them,eight were excellent and seven were acceptable.As to the first-order variables,the centralized drugs procurement policy still lacks incentives and constraints.The comparative results show that there are differences in the content and structure of policies,but they are strongly related to each other.Chinese centralized drug procurement policy has been basically formed,which is closely related to medical insurance and medical policies.However,it is still necessary to pay attention to the structure of the policy to ensure the elaboration of the policy content.展开更多
This study investigates how the uncertainty surrounding cryptocurrency affects cryptocurrency returns(CR)by employing various wavelet techniques.We concentrate on the recently published cryptocurrency uncertainty inde...This study investigates how the uncertainty surrounding cryptocurrency affects cryptocurrency returns(CR)by employing various wavelet techniques.We concentrate on the recently published cryptocurrency uncertainty index(UCRY)and the top eight cryptocurrencies by market capitalization from December 30,2013,to June 30,2023.Our results showed that the UCRY index strongly predicted CR.In particular,the UCRY index has a leading position at all frequencies for all cryptocurrencies in our sample.Additionally,when the impacts of economic policy uncertainty and the volatility index are eliminated,the significant comovement of UCRY-CR remains unchanged for the short-,medium-,and long-term investment horizons.Therefore,we conclude that the UCRY-CR relationship is both persistent and pervasive.Our study contributes toward the literature on the relationships between cryptocurrencies and market uncertainties,as well as toward investors who use uncertainty indices to design investment strategies for their portfolios.展开更多
As a critical mechanical characteristic of rock,brittleness significantly influences fracture modes and damage evolution processes.Accurate quantitative evaluation of brittleness is essential for ensuring the stabilit...As a critical mechanical characteristic of rock,brittleness significantly influences fracture modes and damage evolution processes.Accurate quantitative evaluation of brittleness is essential for ensuring the stability of various engineering applications.Based on the pre-peak and post-peak stages of the rock stress-strain curve,this study constructed a brittleness index BI^(*).The index quantifies the ability of rock to resist plastic deformation during the pre-peak crack growth stage and evaluates the intensity of strength drop during the post-peak softening stage.Another index,BII,was established based on the degree of pre-peak elastic energy accumulation and the instability characteristics of post-peak dissipated energy.This index reflects the essential properties of rock failure by revealing the energy evolution mechanism.Furthermore,by defining a damage variable from the energy dissipation over the entire deformation process,an index B_(D)was introduced to evaluate brittleness from the perspective of internal damage development.Triaxial compression and cyclic loading tests were conducted on rocks of different lithologies to evaluate the new index.The influences of confining pressure and lithology on rock brittleness were analyzed,along with the sensitivity analysis of various brittleness index parameters.The results indicated that the proposed brittleness indices accurately distinguish the brittleness differences among various lithologies and show effective consistency with the failure modes of specimens under different confining pressures.Meanwhile,different brittleness indices were affected by confining pressure and lithology to different degrees.The post-peak softening stage of rock played a particularly significant role in brittleness analysis.A brittleness classification system under different confining pressures and lithologies was established.The research results contribute to the enhancement and refinement of the rock brittleness evaluation system.展开更多
reshwater essential for civilization faces risk from untreated effluents discharged by industries,agriculture,urban areas,and other sources.Increasing demand and abstraction of freshwater deteriorate the pollution sce...reshwater essential for civilization faces risk from untreated effluents discharged by industries,agriculture,urban areas,and other sources.Increasing demand and abstraction of freshwater deteriorate the pollution scenario more.Hence,water quality analysis(WQA)is an important task for researchers and policymakers to maintain sustainability and public health.This study aims to gather and discuss the methods used for WQA by the researchers,focusing on their advantages and limitations.Simultaneously,this study compares different WQA methods,discussing their trends and future directions.Publications from the past decade on WQA are reviewed,and insights are explored to aggregate them in particular categories.Three major approaches,namely—water quality indexing,water quality modeling(WQM)and artificial intelligence-based WQM,are recognized.Different methodologies adopted to execute these three approaches are presented in this study,which leads to formulate a comparative discussion.Using statistical operations and soft computing techniques have been done by researchers to combat the subjectivity error in indexing.To achieve better results,WQMs are being modified to incorporate the physical processes influencing water quality more robustly.The utilization of artificial intelligence was primarily restricted to conventional networks,but in the last 5 years,implications of deep learning have increased rapidly and exhibited good results with the hybridization of feature extracting and time series modeling.Overall,this study is a valuable resource for researchers dedicated to WQA.展开更多
Ionospheric scintillation refers to rapid radio signal amplitude and phase fluctuations due to small-scale irregularities in the ionosphere.Occurring primarily at equatorial and low latitudes,scintillation is linked t...Ionospheric scintillation refers to rapid radio signal amplitude and phase fluctuations due to small-scale irregularities in the ionosphere.Occurring primarily at equatorial and low latitudes,scintillation is linked to equatorial plasma bubbles(EPBs),regions of depleted plasma density that form after sunset.Ionospheric scintillation typically occurs from post-sunset hours until midnight.Post-sunset EPBs can be enhanced or suppressed during geomagnetic storms,depending on local sunset timing and how it relates to the storm's main or recovery phases.This study analyzes ionospheric scintillation in Indonesia,located at low geomagnetic and geographic latitudes,during geomagnetic events from 2003 to 2024.Using the S4 index,scintillation was examined with data from seven observation stations during geomagnetic storm events.Geomagnetic activity was evaluated using Dst,SYM-H,and AE indices,employing Superposed Epoch Analysis(SEA)to assess scintillation occurrence linked to minimum SYM-H,defined as epoch 0 to represent the storm peak or the onset of recovery phase in each event.The analysis categorized geomagnetic storms into weak-moderate(–100 nT<min.Dst≤–30 nT)and strong(min.Dst≤–100 nT),and examined their dependence on the local time of minimum SYM-H.Results indicate that scintillation first appears~6 hours after epoch 0 in weak-moderate geomagnetic storms,and~12 hours after epoch 0 in strong geomagnetic storms.The average AE index returns to its baseline value(quiet condition)~6 and~12 hours after epoch 0 for weak-moderate and strong geomagnetic storms,respectively.Further analysis based on the classification of the local time of epoch 0 shows that scintillation occurrence is not observed in post-sunset hours when epoch 0 falls between 16:00 and 19:00 LT for weak-moderate geomagnetic storms.In strong geomagnetic storms,scintillation occurrence during post-sunset hours is absent when epoch 0 is between 10:00 and 19:00 LT.Notably,when the minimum SYM-H(epoch 0)nearly coincides with local sunset,scintillation activity occurs around sunset in both weak-moderate and strong geomagnetic storms.Furthermore,when epoch 0 falls within midnight until early morning,scintillation can be generated in the post-sunset hours before epoch 0.Still,post-midnight scintillation is not observed in the equatorial region during the recovery phase of either weak-moderate and strong storm events.Our findings show that when sunset falls before or coincide with epoch 0,the likelihood of post-sunset EPB and scintillation increases,due to the prompt-penetration electric field(PPEF)in the main phase of storm.The disturbance dynamo electric field(DDEF)in the recovery phase driven by equatorward winds from auroral Joule heating operates for at least 6-and 12-hours post-epoch 0 in the cases of weak-moderate and strong geomagnetic storms,respectively.When the local sunset falls within these operational DDEF periods,post-sunset EPBs will likely be suppressed,inhibiting ionospheric scintillation during post-sunset hours.Finally,this study provides essential information for developing more accurate ionospheric scintillation prediction models in space weather services in equatorial regions.展开更多
In the context of post-stimulation shale gas wells,the terms“shut-in”and“flowback”refer to two critical phases that occur after hydraulic fracturing(fracking)has been completed.These stages play a crucial role in ...In the context of post-stimulation shale gas wells,the terms“shut-in”and“flowback”refer to two critical phases that occur after hydraulic fracturing(fracking)has been completed.These stages play a crucial role in determining both the well’s initial production performance and its long-term hydrocarbon recovery.By establishing a comprehensive big data analysis platform,the flowback dynamics of over 1000 shale gas wells were analyzed in this work,leading to the development of an index system for evaluating flowback production capacity.Additionally,a shut-in chart was created for wells with different types of post-stimulation fracture networks,providing a structured approach to optimizing production strategies.A dynamic analysis method for flowback was also developed,using daily pressure drop and artificial fracture conductivity as key indicators.This method offers a systematic and effective approach to managing the shut-in and flowback processes for gas wells.Field trials demonstrated significant improvements:the probability of sand production was reduced,gas breakthrough time was extended,artificial fracture conductivity was enhanced,and the average estimated ultimate recovery(EUR)per well increased.展开更多
基金the Project of the National Key Research and Development Program of China(Grant No.:2022YFC3501802)National Natural Science Foundation of China(Grant No.:82204614)+2 种基金Zhejiang Provincial Basic Public Welfare Research Program(Program No.:LTGC24H280002)Xiao Li and Prof.Tianxiang Li(Tianjin University of Traditional Chinese Medicine)for collecting and identifying all the CR samplesYingniang Li from the Core Facilities,Zhejiang University School of Medicine for their technical support.
文摘In general,bioassay-guided fractionation and isolation of bioactive constituents from botanical materials frequently ended up with the reward of a single compound.However,botanical materials typically exert their therapeutic actions through multi-pathway effects due to the intrinsic complex nature of chemical constituents.In addition,the content of bioactive compounds in botanical materials is largely dependent on humidity,temperature,soil,especially geographical origins,from which rapid and accurate identification of plant materials is pressingly needed.These long-standing obstacles collectively impede the deep exploi-tation and application of these versatile natural sources.To address the challenges,a new paradigm inte-grating biogravimetric analyses and machine learning-driven origin classification(BAMLOC)was developed.The biogravimetric analyses are based on absolute qHNMR quantification and in vivo zebrafish model-assisted activity index calculation,by which bioactive substance groups jointly responsible for the bioactivities in all fractions are pinpointed before any isolation effort.To differentiate origin-different botanical materials varying in the content of bioactive substance groups,principal component analysis,linear discriminant analysis,and hierarchical cluster analysis in conjunction with supervised support vector machine are employed to classify and predict production areas based on the detection of volatile organic compounds by E-nose and gas chromatography-mass spectrometry(GC-MS).Expanding BAMLOC to Codonopsis Radix enables the identification of polyacetylenes and pyrrolidine alkaloids as the bioactive substance group for immune restoration effect and accurately determines the origins of plants.This study advances the toolbox for the discovery of bioactive compounds from complex mixtures and lays a more definitive foundation for the in-depth utilization of botanical materials.
基金Research Project of Hunan Province Education Department(No.14C0972)
文摘The reliability and availability of the reactor protection system (RPS) can be improved by using M out of N judg- ment system. By analyzing two quantitative indicators, the rate of refusal to operate and mal-operation rate, a strict math- ematical formula and an approximate calculation are stated. The differences of a series of judgment systems are discussed on condition that the unsafe failure probability and the security failure probability are both 0.1. Based on given parameters (A, B,P, Q): A is upper limit of the refusal rate for the RPS, B is upper limit of the real-operation rate, P and Q are basic protection unit rates corresponding to refusal rate and mal-operation rate, respectively. According to these parameters, the values of N and M can be solved.
基金Under the auspices of National Natural Sciences Foundation of China(No.41230745)Major Program of High Resolution Earth Observation System(No.30-Y30B13-9003-14/16-02)
文摘Although the quantification and valuation of ecosystem services have been studied for a long time, few studies have specifi- cally focused on the quantification of tradeoffs between ecosystem services and tradeoff hotspots, Based on previous studies of ecosys- tem service assessment, we proposed a feasible method to analyze the tradeoffs between ecosystem services, including determination of their relationship, quantification of tradeoffs, and identification of tradeoff hotspots. Potential influencing factors were then further ana- lyzed. The Yanhe Basin in the Loess Plateau was selected as an example to demonstrate the application process. Firstly, the amounts of net primary production (NPP) and water yield (WY) in 2000 and 2008 were estimated by using biophysical models, Secondly, correla- tion analysis was used to indicate the tradeoffs between NPP and WY. Thirdly, tradeoff index (TINpp/wy) was established to quantify the extent of tradeoffs between NPP and WY, and the average value of TINpp/wy is 24.4 g/(mm·m2) for the Yanhe Basin between 2000 and 2008. Finally, the tradeoff hotspots were identified. The results indicated that the area of lowest tradeoff index concentrated in the mid- dle part of the Yanhe Basin and marginal areas of the southern basin. Map overlapping was used for preliminary analysis to seek poten- tial influencing factors, and the results showed that shrub was the best suited for growing in the Yanhe Basin, but also was a potential irtfluencing factor for formulatiort of the tradeoff hotspots. The concept of tradeoff index could also be used to quantify the degree of synergy between different ecosystem services. The method to identify the tradeoff hotspots could help us to narrow the scope of study area for further research on the relationship among ecosystem services and concentrate on the potential factors for formation of tradeoff between ecosystem services, enhance the capacity to maintain the sustainability of ecosystem.
基金supported by the“MOST”under Grant No.104-2221-E-259-024-MY2
文摘Due to the increasing demand for security, the development of intelligent surveillance systems has attracted considerable attention in recent years. This study aims to develop a system that is able to identify whether or not the people need help in a public place. Different from previous work, our work considers not only the behaviors of the target person but also the interaction between him and nearby people. In the paper, we propose an event alarm system which can detect the human behaviors and recognize the happening event through integrating the results generated from the single and group behavior analysis. Several new effective features are proposed in the study. Besides, a mechanism capable of extracting one-to-one and multiple-to-one relations is also developed. Experimental results show that the proposed approach can correctly detect human behaviors and provide the alarm messages when emergency events occur.
文摘A combined cluster and regression analysis were performed for the first time to identify rainfall threshold that triggers landslide events in Amboori, Kerala, India. Amboori is a tropical area that is highly vulnerable to landslides. The 2, 3, and 5-day antecedent rainfall data versus daily rainfall was clustered to identify a cluster of critical events that could potentially trigger landslides. Further, the cluster of critical events was utilized for regression analysis to develop the threshold equations. The 5-day antecedent(xvariable) vs. daily rainfall(y-variable) provided the best fit to the data with a threshold equation of y = 80.7-0.1981 x. The intercept of the equation indicates that if the 5-day antecedent rainfall is zero, the minimum daily rainfall needed to trigger the landslide in the Amboori region would be 80.7 mm. The negative coefficient of the antecedent rainfall indicates that when the cumulative antecedent rainfall increases, the amount of daily rainfall required to trigger monsoon landslide decreases. The coefficient value indicates that the contribution of the 5-day antecedent rainfall is~20% to the landslide trigger threshold. The slope stability analysis carried out for the area, using Probabilistic Infinite Slope Analysis Model(PISA-m), was utilized to identify the areas vulnerable to landslide in the region. The locations in the area where past landslides have occurred demonstrate lower Factors of Safety(FS) in the slope stability analysis. Thus, rainfall threshold analysis together with the FS values from slope stability can be suitable for developing a simple, cost-effective, and comprehensive early-warning system for shallow landslides in Amboori and similar regions.
基金Supported by the National Natural Science Foundation of China(71063015)the Eleventh Five-Year Plan Social Sciences Project in Jiangxi Province(10YJ61)the Science and Technology Project of the Education Department of Jiangxi Province(GJJ11271)
文摘By using emergy analysis theory and methods,we conduct quantitative analysis on the input and output of emergy,and sustainable development of agro-ecological system in Poyang Lake Area.The results show that compared with the national average,the environmental loading ratio is relatively low in this area;the net emergy yield rate is high;the sustainable development ability is strong.Finally according to the results of emergy analysis,corresponding countermeasures are put forward as follows:develop agriculture based on the existing rich natural resources;increase technological inputs;develop circular agriculture;promote sustainable agricultural development.
基金The National Natural Science Foundation of China under contract No.31772852the Fundamental Research Funds for the Central Universities under contract No.201612004。
文摘This study used Ecopath model of the Jiaozhou Bay as an example to evaluate the effect of stomach sample size of three fish species on the projection of this model. The derived ecosystem indices were classified into three categories:(1) direct indices, like the trophic level of species, influenced by stomach sample size directly;(2)indirect indices, like ecology efficiency(EE) of invertebrates, influenced by the multiple prey-predator relationships;and(3) systemic indices, like total system throughout(TST), describing the status of the whole ecosystem. The influences of different stomach sample sizes on these indices were evaluated. The results suggest that systemic indices of the ecosystem model were robust to stomach sample sizes, whereas specific indices related to species were indicated to be with low accuracy and precision when stomach samples were insufficient.The indices became more uncertain when the stomach sample sizes varied for more species. This study enhances the understanding of how the quality of diet composition data influences ecosystem modeling outputs. The results can also guide the design of stomach content analysis for developing ecosystem models.
基金supported by the National Natural Science Foundation of China(72271124,72071111).
文摘Aiming at the characteristics of multi-stage and(extremely)small samples of the identification problem of key effectiveness indexes of weapon equipment system-of-systems(WESoS),a Bayesian intelligent identification and inference model for system effectiveness assessment indexes based on dynamic grey incidence is proposed.The method uses multi-layer Bayesian techniques,makes full use of historical statistics and empirical information,and determines the Bayesian estima-tion of the incidence degree of indexes,which effectively solves the difficulties of small sample size of effectiveness indexes and difficulty in obtaining incidence rules between indexes.Sec-ondly,The method quantifies the incidence relationship between evaluation indexes and combat effectiveness based on Bayesian posterior grey incidence,and then identifies key system effec-tiveness evaluation indexes.Finally,the proposed method is applied to a case of screening key effectiveness indexes of a missile defensive system,and the analysis results show that the proposed method can fuse multi-moment information and extract multi-stage key indexes,and has good data extraction capability in the case of small samples.
基金supported by National Natural Science Foundation of China (Grant No. 12 071 042)Beijing Natural Science Foundation (Grant No. 1 202 006)。
文摘Under investigation in this paper is a relativistic Toda lattice system with one perturbation parameterαabbreviated as RTLαsystem by Suris,which may describe the motions of particles in lattices interacting through an exponential interaction force.First of all,an integrable lattice hierarchy associated with an RTLαsystem is constructed,from which some relevant integrable properties such as Hamiltonian structures,Liouville integrability and conservation laws are investigated.Secondly,the discrete generalized(m,2 N-m)-fold Darboux transformation is constructed to derive multi-soliton solutions,higher-order rational and semirational solutions,and their mixed solutions of an RTLαsystem.The soliton elastic interactions and details of rational solutions are analyzed via the graphics and asymptotic analysis.Finally,soliton dynamical evolutions are investigated via numerical simulations,showing that a small noise has very little effect on the soliton propagation.These results may provide new insight into nonlinear lattice dynamics described by RTLαsystem.
基金supported by the National Natural Science Foundation of China(Nos. U1131121,11303021,U1231202,11473037 and 11373073)
文摘Photometric observations of AH Cnc, a W UMa-type system in the open cluster M67, were car- fled out by using the 50BIN telescope. About 100h of time-series/3- and V-band data were taken, based on which eight new times of light minima were determined. By applying the Wilson-Devinney method, the light curves were modeled and a revised photometric solution of the binary system was derived. We con- firmed that AH Cnc is a deep contact (f = 51%), low mass-ratio (q - 0.156) system. Adopting the distance modulus derived from study of the host cluster, we have re-calculated the physical parameters of the binary system, namely the masses and radii. The masses and radii of the two components were estimated to be respectively 1.188(4-0.061) Me, 1.332(4-0.063) RQ for the primary component and 0.185(4-0.032) Me, 0.592(4-0.051) Re for the secondary. By adding the newly derived minimum timings to all the available data, the period variations of AH Cnc were studied. This shows that the orbital period of the binary is con- tinuously increasing at a rate of dp/dt = 4.29 x 10-10 d yr-1. In addition to the long-term period increase, a cyclic variation with a period of 35.26 yr was determined, which could be attributed to an unresolved tertiary component of the system.
文摘The article analyses several key issues which restrict the effectiveness of fund project peer review work. It analyses the evaluating theory and matter-element theory to access the expert anti-evaluation model, and also studies the expert anti-evaluation index system to support the anti-evaluation method. The practical basis is the true score data of the experts which is collected from the actual anti-evaluation in Liaoning province science and technology fund project peer review system. With the practical experience of the actual project, we prove that the expert index system anti-evaluation model and expert anti-evaluation method can improve the fund project peer review work and play a positive role for the peer review work and also make the review work more scientific and more rational.
基金Heilongjiang Province Higher Educa-tion Basic Research Business Fee Research Project(No.1353MSY YB017)Daqing Normal University Natural Science Foundation(No.19ZR04)。
文摘A model for repairable standby parallel system consisting of two identical components with common cause failure(CCF)and human error is introduced in this article by a semigroup approach.The stability of the system is verified by the pure analysis technique,the co-final related theory and functional analysis method.It is discussed that four different reliability indices of the studied model are consistent with each other both analytically and numerically.The simulations and comparisons demonstrate the validity of the proposed technique.
基金National Natural Science Foundation of China(40505019)
文摘In this study,the relationship between the subsystems of Asian summer monsoon is analyzed using U.S.National Centers for Environmental Protection/National Center for Atmospheric Research reanalysis and Climate Prediction Center Merged Analysis of Precipitation monthly mean precipitation data.The results showed that there is significant correlation between the subsystems of Asian summer monsoon.The changes of intensity over the same period show that weak large-scale Asian monsoon,Southeast Asia monsoon and South Asian monsoon are associated with strong East Asian monsoon and decreasing rainfall in related areas.And when the large-scale Asian monsoon is strong,Southeast Asia and South Asia monsoons will be strong and precipitation will increase.While the Southeast Asia monsoon is strong,the South Asia monsoon is weak and the rainfall of South Asia is decreasing,and vice versa.The various subsystems are significantly correlated for all periods of intensity changes.
文摘Objective To establish a scientific,reliable,objective,and effective clinical comprehensive evaluation system for drugs centralized bidding procurement by government,and to conduct reliability and validity test and empirical analysis of the evaluation index system through simulated measurement.Methods Literature research method was used to select comprehensive evaluation indicators for drugs centralized bidding procurement.Then,Dephi method was applied to screen the final evaluation indicators,and the weight of the indicators was determined using analytic hierarchy process.Results and Conclusion The final clinical efficacy evaluation index system for drugs centralized bidding procurement includes 5 primary indicators and 13 secondary indicators.The experts authority coefficient in this study is high,and their opinions relatively coincide.Through the empirical research,the reliability and structural validity of the indicator system is good.This indicator system enriches methods and tools for scientifically evaluating the clinical efficacy of drugs centralized bidding procurement.
文摘Objective To quantitatively analyze the policy of centralized drug procurement centralized drug procurement in order to provide reference for the subsequent policy formulation and improvement.Methods Text mining method was used to process 15 centralized drugs procurement policies issued at the national level during 2015-2022,and a PMC index evaluation model of centralized drug procurement policies was established.Then,15 centralized drug procurement policies were quantitatively analyzed from the overall and comparative perspective through an evaluation model.Results and Conclusion The average PMC index of 15 centralized drug procurement policies was 6.95,which was acceptable on the whole.Among them,eight were excellent and seven were acceptable.As to the first-order variables,the centralized drugs procurement policy still lacks incentives and constraints.The comparative results show that there are differences in the content and structure of policies,but they are strongly related to each other.Chinese centralized drug procurement policy has been basically formed,which is closely related to medical insurance and medical policies.However,it is still necessary to pay attention to the structure of the policy to ensure the elaboration of the policy content.
文摘This study investigates how the uncertainty surrounding cryptocurrency affects cryptocurrency returns(CR)by employing various wavelet techniques.We concentrate on the recently published cryptocurrency uncertainty index(UCRY)and the top eight cryptocurrencies by market capitalization from December 30,2013,to June 30,2023.Our results showed that the UCRY index strongly predicted CR.In particular,the UCRY index has a leading position at all frequencies for all cryptocurrencies in our sample.Additionally,when the impacts of economic policy uncertainty and the volatility index are eliminated,the significant comovement of UCRY-CR remains unchanged for the short-,medium-,and long-term investment horizons.Therefore,we conclude that the UCRY-CR relationship is both persistent and pervasive.Our study contributes toward the literature on the relationships between cryptocurrencies and market uncertainties,as well as toward investors who use uncertainty indices to design investment strategies for their portfolios.
基金support from the National Natural Science Foundation of China(Grant Nos.12072102 and 12102129).
文摘As a critical mechanical characteristic of rock,brittleness significantly influences fracture modes and damage evolution processes.Accurate quantitative evaluation of brittleness is essential for ensuring the stability of various engineering applications.Based on the pre-peak and post-peak stages of the rock stress-strain curve,this study constructed a brittleness index BI^(*).The index quantifies the ability of rock to resist plastic deformation during the pre-peak crack growth stage and evaluates the intensity of strength drop during the post-peak softening stage.Another index,BII,was established based on the degree of pre-peak elastic energy accumulation and the instability characteristics of post-peak dissipated energy.This index reflects the essential properties of rock failure by revealing the energy evolution mechanism.Furthermore,by defining a damage variable from the energy dissipation over the entire deformation process,an index B_(D)was introduced to evaluate brittleness from the perspective of internal damage development.Triaxial compression and cyclic loading tests were conducted on rocks of different lithologies to evaluate the new index.The influences of confining pressure and lithology on rock brittleness were analyzed,along with the sensitivity analysis of various brittleness index parameters.The results indicated that the proposed brittleness indices accurately distinguish the brittleness differences among various lithologies and show effective consistency with the failure modes of specimens under different confining pressures.Meanwhile,different brittleness indices were affected by confining pressure and lithology to different degrees.The post-peak softening stage of rock played a particularly significant role in brittleness analysis.A brittleness classification system under different confining pressures and lithologies was established.The research results contribute to the enhancement and refinement of the rock brittleness evaluation system.
基金State University Research Excellence(SURE),SERB,GOI,Grant/Award Number:SUR/2022/001557。
文摘reshwater essential for civilization faces risk from untreated effluents discharged by industries,agriculture,urban areas,and other sources.Increasing demand and abstraction of freshwater deteriorate the pollution scenario more.Hence,water quality analysis(WQA)is an important task for researchers and policymakers to maintain sustainability and public health.This study aims to gather and discuss the methods used for WQA by the researchers,focusing on their advantages and limitations.Simultaneously,this study compares different WQA methods,discussing their trends and future directions.Publications from the past decade on WQA are reviewed,and insights are explored to aggregate them in particular categories.Three major approaches,namely—water quality indexing,water quality modeling(WQM)and artificial intelligence-based WQM,are recognized.Different methodologies adopted to execute these three approaches are presented in this study,which leads to formulate a comparative discussion.Using statistical operations and soft computing techniques have been done by researchers to combat the subjectivity error in indexing.To achieve better results,WQMs are being modified to incorporate the physical processes influencing water quality more robustly.The utilization of artificial intelligence was primarily restricted to conventional networks,but in the last 5 years,implications of deep learning have increased rapidly and exhibited good results with the hybridization of feature extracting and time series modeling.Overall,this study is a valuable resource for researchers dedicated to WQA.
基金supported by the National Research and Innovation Agency(BRIN),Indonesia.
文摘Ionospheric scintillation refers to rapid radio signal amplitude and phase fluctuations due to small-scale irregularities in the ionosphere.Occurring primarily at equatorial and low latitudes,scintillation is linked to equatorial plasma bubbles(EPBs),regions of depleted plasma density that form after sunset.Ionospheric scintillation typically occurs from post-sunset hours until midnight.Post-sunset EPBs can be enhanced or suppressed during geomagnetic storms,depending on local sunset timing and how it relates to the storm's main or recovery phases.This study analyzes ionospheric scintillation in Indonesia,located at low geomagnetic and geographic latitudes,during geomagnetic events from 2003 to 2024.Using the S4 index,scintillation was examined with data from seven observation stations during geomagnetic storm events.Geomagnetic activity was evaluated using Dst,SYM-H,and AE indices,employing Superposed Epoch Analysis(SEA)to assess scintillation occurrence linked to minimum SYM-H,defined as epoch 0 to represent the storm peak or the onset of recovery phase in each event.The analysis categorized geomagnetic storms into weak-moderate(–100 nT<min.Dst≤–30 nT)and strong(min.Dst≤–100 nT),and examined their dependence on the local time of minimum SYM-H.Results indicate that scintillation first appears~6 hours after epoch 0 in weak-moderate geomagnetic storms,and~12 hours after epoch 0 in strong geomagnetic storms.The average AE index returns to its baseline value(quiet condition)~6 and~12 hours after epoch 0 for weak-moderate and strong geomagnetic storms,respectively.Further analysis based on the classification of the local time of epoch 0 shows that scintillation occurrence is not observed in post-sunset hours when epoch 0 falls between 16:00 and 19:00 LT for weak-moderate geomagnetic storms.In strong geomagnetic storms,scintillation occurrence during post-sunset hours is absent when epoch 0 is between 10:00 and 19:00 LT.Notably,when the minimum SYM-H(epoch 0)nearly coincides with local sunset,scintillation activity occurs around sunset in both weak-moderate and strong geomagnetic storms.Furthermore,when epoch 0 falls within midnight until early morning,scintillation can be generated in the post-sunset hours before epoch 0.Still,post-midnight scintillation is not observed in the equatorial region during the recovery phase of either weak-moderate and strong storm events.Our findings show that when sunset falls before or coincide with epoch 0,the likelihood of post-sunset EPB and scintillation increases,due to the prompt-penetration electric field(PPEF)in the main phase of storm.The disturbance dynamo electric field(DDEF)in the recovery phase driven by equatorward winds from auroral Joule heating operates for at least 6-and 12-hours post-epoch 0 in the cases of weak-moderate and strong geomagnetic storms,respectively.When the local sunset falls within these operational DDEF periods,post-sunset EPBs will likely be suppressed,inhibiting ionospheric scintillation during post-sunset hours.Finally,this study provides essential information for developing more accurate ionospheric scintillation prediction models in space weather services in equatorial regions.
基金PetroChina Research Applied Science and Technology Project,“Shale Gas Scale Increase Production and Exploration andDevelopment Technology-Research and Application of Key Technology of Deep Shale Gas Scale Production”(No.2023ZZ21YJ01).
文摘In the context of post-stimulation shale gas wells,the terms“shut-in”and“flowback”refer to two critical phases that occur after hydraulic fracturing(fracking)has been completed.These stages play a crucial role in determining both the well’s initial production performance and its long-term hydrocarbon recovery.By establishing a comprehensive big data analysis platform,the flowback dynamics of over 1000 shale gas wells were analyzed in this work,leading to the development of an index system for evaluating flowback production capacity.Additionally,a shut-in chart was created for wells with different types of post-stimulation fracture networks,providing a structured approach to optimizing production strategies.A dynamic analysis method for flowback was also developed,using daily pressure drop and artificial fracture conductivity as key indicators.This method offers a systematic and effective approach to managing the shut-in and flowback processes for gas wells.Field trials demonstrated significant improvements:the probability of sand production was reduced,gas breakthrough time was extended,artificial fracture conductivity was enhanced,and the average estimated ultimate recovery(EUR)per well increased.