背景:选择合适的陶瓷材料对口腔全瓷美学修复尤为重要。在口腔修复体美学性能研究中,多使用色差值和透光性作为评价指标,影响全瓷修复体色差和透光性的因素主要有陶瓷材料的种类、色调、厚度、加工工艺以及基牙颜色和粘接剂等。目的:探...背景:选择合适的陶瓷材料对口腔全瓷美学修复尤为重要。在口腔修复体美学性能研究中,多使用色差值和透光性作为评价指标,影响全瓷修复体色差和透光性的因素主要有陶瓷材料的种类、色调、厚度、加工工艺以及基牙颜色和粘接剂等。目的:探究材料种类及厚度对全瓷修复体美学性能的影响。方法:选取各类可切削陶瓷中6种代表性的材料(常规氧化锆ZR-ST、树脂基陶瓷RC、高透氧化锆ZR-TT、白榴石增强玻璃陶瓷LE、二硅酸锂玻璃陶瓷LD及长石质瓷FP),每种材料分别制备成0.8,1.0,1.5 mm厚的10.0 mm×12.5 mm长方体陶瓷试件,进行对应的表面处理后与树脂试件(代表基牙)粘接制成陶瓷-树脂复合体试件,测算粘接前后的CIEL^(*)a^(*)b^(*)、色差值ΔE及透光率值。结果与结论:①当基牙厚度未达到无限光学厚度时,陶瓷材料的种类和厚度共同影响修复体的颜色和透光率值。当陶瓷试件厚度不超过1.0 mm时,与树脂片粘接后的颜色普遍向蓝红趋近;当陶瓷试件厚度为1.5 mm时,与树脂片粘接后的颜色普遍向蓝绿趋近,提示在全瓷修复体比色时可通过颜色预补偿优化美学匹配。②除厚度1.5 mm ZR-ST陶瓷试件外,粘接后各组陶瓷试件与树脂片之间的色差值ΔE均低于5,0.8 mm ZR-ST陶瓷试件与树脂片之间的色差值ΔE接近3,1.0 mm ZR-TT陶瓷试件与树脂片之间的色差值ΔE小于3,提示在微创修复过程中,若患牙透光率不高且美学修复空间不足、对材料强度要求高时,ZR-TT和ZR-ST陶瓷可能是潜在的选择。③陶瓷试件的透光率值在粘接后降低,并随陶瓷厚度的增加显著降低。RC陶瓷试件的透光率值高,粘接后与树脂片之间的色差值ΔE接近3,光学性能出色。展开更多
Passiflora incarnata L.,commonly known as passionflower,is traditionally cultivated as an ornamental plant but has demonstrated diverse therapeutic potential.Its pharmacological effects are attributed to bioactive com...Passiflora incarnata L.,commonly known as passionflower,is traditionally cultivated as an ornamental plant but has demonstrated diverse therapeutic potential.Its pharmacological effects are attributed to bioactive compounds such as flavonoids and alkaloids,which influence multiple biological pathways.This review aims to summarise and critically analyse recent findings on the pharmacological properties of Passiflora incarnata L.,focusing on its neuropsychiatric,antioxidant,antimicrobial,and anticancer activities.A targeted literature search was conducted in PubMed,Scopus,Web of Science,and Google Scholar for peer-reviewed publications between 2000 to 2025.Relevant articles were screened,and a more appropriate article related to the objective of the review was selected.Some classical papers are also cited as per the requirement of the topic.Passiflora incarnata L.showed multifunctional medicinal properties with various applications in neuropsychiatry,oxidative stress management,antimicrobial agent,and as an anticancer agent.The U.S.Food and Drug Administration categorizes passionflower extracts as“generally recognized as safe”.However,most evidence remains preclinical,with methodological variation limiting generalisation.Standardised formulation,robust clinical trials,and in-depth in vivo studies are essential to establish its therapeutic relevance and safety in modern medicine.展开更多
The nervous system function requires a precise but plastic neural architecture.The neuronal shape dictates how neurons interact with each other and with other cells,being the morphology of dendrites and axons the cent...The nervous system function requires a precise but plastic neural architecture.The neuronal shape dictates how neurons interact with each other and with other cells,being the morphology of dendrites and axons the central determinant of the functional properties of neurons and neural circuits.The topological and structural morphology of axons and dendrites defines and determines how synapses are conformed.The morphological diversity of axon and dendrite arborization governs the neuron’s inputs,synaptic integration,neuronal computation,signal transmission,and network circuitry,hence defining the particular connectivity and function of the different brain areas.展开更多
车型:2016年奥迪A6L,配置CYY发动机、RKW变速器。行驶里程:220548km。故障现象:中央M M I屏幕不亮,但媒体播放仍有声音,具体情况如图1所示。故障诊断:使用诊断仪对信息电子装置1(MIB)进行检测,读取到的故障码为U10E200多媒体系统显示单...车型:2016年奥迪A6L,配置CYY发动机、RKW变速器。行驶里程:220548km。故障现象:中央M M I屏幕不亮,但媒体播放仍有声音,具体情况如图1所示。故障诊断:使用诊断仪对信息电子装置1(MIB)进行检测,读取到的故障码为U10E200多媒体系统显示单元1无通信,如图2所示。展开更多
文摘背景:选择合适的陶瓷材料对口腔全瓷美学修复尤为重要。在口腔修复体美学性能研究中,多使用色差值和透光性作为评价指标,影响全瓷修复体色差和透光性的因素主要有陶瓷材料的种类、色调、厚度、加工工艺以及基牙颜色和粘接剂等。目的:探究材料种类及厚度对全瓷修复体美学性能的影响。方法:选取各类可切削陶瓷中6种代表性的材料(常规氧化锆ZR-ST、树脂基陶瓷RC、高透氧化锆ZR-TT、白榴石增强玻璃陶瓷LE、二硅酸锂玻璃陶瓷LD及长石质瓷FP),每种材料分别制备成0.8,1.0,1.5 mm厚的10.0 mm×12.5 mm长方体陶瓷试件,进行对应的表面处理后与树脂试件(代表基牙)粘接制成陶瓷-树脂复合体试件,测算粘接前后的CIEL^(*)a^(*)b^(*)、色差值ΔE及透光率值。结果与结论:①当基牙厚度未达到无限光学厚度时,陶瓷材料的种类和厚度共同影响修复体的颜色和透光率值。当陶瓷试件厚度不超过1.0 mm时,与树脂片粘接后的颜色普遍向蓝红趋近;当陶瓷试件厚度为1.5 mm时,与树脂片粘接后的颜色普遍向蓝绿趋近,提示在全瓷修复体比色时可通过颜色预补偿优化美学匹配。②除厚度1.5 mm ZR-ST陶瓷试件外,粘接后各组陶瓷试件与树脂片之间的色差值ΔE均低于5,0.8 mm ZR-ST陶瓷试件与树脂片之间的色差值ΔE接近3,1.0 mm ZR-TT陶瓷试件与树脂片之间的色差值ΔE小于3,提示在微创修复过程中,若患牙透光率不高且美学修复空间不足、对材料强度要求高时,ZR-TT和ZR-ST陶瓷可能是潜在的选择。③陶瓷试件的透光率值在粘接后降低,并随陶瓷厚度的增加显著降低。RC陶瓷试件的透光率值高,粘接后与树脂片之间的色差值ΔE接近3,光学性能出色。
文摘Passiflora incarnata L.,commonly known as passionflower,is traditionally cultivated as an ornamental plant but has demonstrated diverse therapeutic potential.Its pharmacological effects are attributed to bioactive compounds such as flavonoids and alkaloids,which influence multiple biological pathways.This review aims to summarise and critically analyse recent findings on the pharmacological properties of Passiflora incarnata L.,focusing on its neuropsychiatric,antioxidant,antimicrobial,and anticancer activities.A targeted literature search was conducted in PubMed,Scopus,Web of Science,and Google Scholar for peer-reviewed publications between 2000 to 2025.Relevant articles were screened,and a more appropriate article related to the objective of the review was selected.Some classical papers are also cited as per the requirement of the topic.Passiflora incarnata L.showed multifunctional medicinal properties with various applications in neuropsychiatry,oxidative stress management,antimicrobial agent,and as an anticancer agent.The U.S.Food and Drug Administration categorizes passionflower extracts as“generally recognized as safe”.However,most evidence remains preclinical,with methodological variation limiting generalisation.Standardised formulation,robust clinical trials,and in-depth in vivo studies are essential to establish its therapeutic relevance and safety in modern medicine.
基金supported by the Wellcome Trust(grant No.103852).
文摘The nervous system function requires a precise but plastic neural architecture.The neuronal shape dictates how neurons interact with each other and with other cells,being the morphology of dendrites and axons the central determinant of the functional properties of neurons and neural circuits.The topological and structural morphology of axons and dendrites defines and determines how synapses are conformed.The morphological diversity of axon and dendrite arborization governs the neuron’s inputs,synaptic integration,neuronal computation,signal transmission,and network circuitry,hence defining the particular connectivity and function of the different brain areas.