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The Automorphism Group of Green Algebra of 9-Dimensional Taft Hopf Algebra 被引量:1
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作者 Ruju Zhao Chengtao Yuan Libin Li 《Algebra Colloquium》 SCIE CSCD 2020年第4期767-798,共32页
Let H3 be the 9-dimensional Taft Hopf algebra,let r(H3)be the corresponding Green ring of H3,and let Aut(R(H3))be the automorphism group of Green algebra R(H3)=R■Zr(H3)over the real number fieldR.We prove that the qu... Let H3 be the 9-dimensional Taft Hopf algebra,let r(H3)be the corresponding Green ring of H3,and let Aut(R(H3))be the automorphism group of Green algebra R(H3)=R■Zr(H3)over the real number fieldR.We prove that the quotient group Aut(R(H3))/T1 is isomorphic to the direct product of the dihedral group of order 12 and the cyclic group of order 2,where T1 is the isomorphism class which contains the identity map and is isomorphic to a group G={(c,d)∈R^(2)∣∣(c,d)≠(−1/3,−1/6)}with multiplication given by(c1,d1)⋅(c2,d2)=(c1+c2+2c1c2−4d1d2+2c1d2+2d1c2,d1+d2−2c1c2−2d1d2+4c1d2+4d1c2). 展开更多
关键词 auto morphism group Green ring Green algebra 9-dimensional Taft Hopf algebra
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基质金属蛋白酶9介导线粒体自噬调控成骨及成肌
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作者 王思微 姚啸生 +3 位作者 戚晓楠 王禹 崔海舰 赵佳萱 《中国组织工程研究》 北大核心 2026年第18期4557-4567,共11页
背景:基质金属蛋白酶9可以影响成骨和成肌分化,但是其具体调控机制不甚清楚。目的:探讨氧化应激损伤对小鼠MC3T3-E1细胞和C2C12细胞线粒体自噬的影响,进一步研究基质金属蛋白酶9作为关键分子通过介导PTEN诱导激酶1/Parkin信号通路调控... 背景:基质金属蛋白酶9可以影响成骨和成肌分化,但是其具体调控机制不甚清楚。目的:探讨氧化应激损伤对小鼠MC3T3-E1细胞和C2C12细胞线粒体自噬的影响,进一步研究基质金属蛋白酶9作为关键分子通过介导PTEN诱导激酶1/Parkin信号通路调控线粒体自噬并影响成骨、成肌分化的作用。方法:选取小鼠C2C12细胞和MC3T3-E1细胞进行分化与培养,分别设置对照组、模型组(H2O2诱导氧化损伤)、GM6001(基质金属蛋白酶9抑制剂)组、3-甲基腺嘌呤(PTEN诱导激酶1/Parkin通路抑制剂)组,各组细胞处理时间均为24 h。应用流式细胞术检测细胞内线粒体膜电位、活性氧水平;透射电镜观察细胞线粒体损伤及自噬情况;Western blot检测基质金属蛋白酶9蛋白表达;qRT-PCR和Western blot检测P62、微管相关蛋白轻链3、PTEN诱导激酶1、Parkin的mRNA和蛋白表达;Western blot检测MC3T3-E1细胞中成骨蛋白骨钙素、骨桥蛋白、Runt相关转录因子2蛋白表达;qRT-PCR法检测C2C12细胞中成肌基因生肌因子5、生肌因子6、生肌决定因子1、肌细胞生成素mRNA表达。结果与结论:①在MC3T3-E1细胞和C2C12细胞中,与对照组相比,模型组、GM6001组、3-甲基腺嘌呤组线粒体膜电位均降低,活性氧水平均升高;与模型组相比,GM6001组活性氧水平降低;与GM6001组相比,3-甲基腺嘌呤组活性氧水平升高;②透射电镜观察模型组线粒体损伤较为严重,线粒体自噬形成;GM6001组线粒体损伤情况有所改善;3-甲基腺嘌呤组线粒体损伤情况较模型组减轻,自噬程度减弱;③与对照组相比,模型组、GM6001组、3-甲基腺嘌呤组基质金属蛋白酶9蛋白表达升高;与模型组相比,3-甲基腺嘌呤组基质金属蛋白酶9蛋白表达显著降低;与3-甲基腺嘌呤组相比,GM6001组基质金属蛋白酶9蛋白表达显著降低;④与对照组相比,模型组P62 mRNA及蛋白表达降低,GM6001组进一步降低,3-甲基腺嘌呤组升高;与对照组相比,模型组微管相关蛋白轻链3Ⅱ、微管相关蛋白轻链3Ⅰ、PTEN诱导激酶1、Parkin mRNA及蛋白表达升高,GM6001组进一步升高,3-甲基腺嘌呤组降低;⑤在MC3T3-E1细胞系中,与对照组相比,模型组、GM6001组、3-甲基腺嘌呤组骨钙素、骨桥蛋白、Runt相关转录因子2蛋白表达降低;与模型组相比,GM6001组骨钙素、骨桥蛋白表达升高;与GM6001组相比,3-甲基腺嘌呤组骨钙素、骨桥蛋白表达降低;⑥在C2C12细胞系中,与对照组相比,模型组、GM6001组、3-甲基腺嘌呤组生肌因子5、生肌因子6、生肌决定因子1、肌细胞生成素mRNA表达降低;与模型组相比,GM6001组上述成肌基因表达升高;与GM6001组相比,3-甲基腺嘌呤组上述成肌基因表达降低。结果表明,基质金属蛋白酶9在氧化损伤模型中高表达,其抑制剂可以增强氧化损伤环境下的线粒体自噬,这种调控是基于PTEN诱导激酶1/Parkin通路的激活,并对成骨、成肌分化具有促进作用。 展开更多
关键词 骨质疏松症 肌少症 肌少-骨质疏松症 基质金属蛋白酶9 线粒体自噬 PINK1/Parkin通路 成骨分化 成肌分化
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面向区块链的UC安全门限SM9签名方案
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作者 董佶圣 李聪 +3 位作者 沈子楠 胡达齐 沈晴霓 吴中海 《计算机研究与发展》 北大核心 2026年第1期227-242,共16页
近年来,区块链受到公众广泛关注,数字签名方案是区块链中交易的合法鉴权方式。门限签名方案可以使得由单一参与方控制的密钥同时被多个参与方管理,只有在超过阈值的多个参与方同时进行签名的情况下才能完成交易签名,扩展了加密数字货币... 近年来,区块链受到公众广泛关注,数字签名方案是区块链中交易的合法鉴权方式。门限签名方案可以使得由单一参与方控制的密钥同时被多个参与方管理,只有在超过阈值的多个参与方同时进行签名的情况下才能完成交易签名,扩展了加密数字货币的应用方式和应用场景,降低了单点故障的风险。然而,目前的门限签名方案多局限于ECDSA(elliptic curve digital signature algorithm)等传统公钥签名算法,由此带来的公钥证书存储和管理开销较大。基于标识的密码体制可以有效解决这一问题,但还没有相应的针对基于国密SM9标识密码的门限签名方案研究。实现门限签名方案通常需要两方秘密分享转换方案,针对现有基于Paillier加密算法的两方秘密分享转换方案效率低的问题,提出了一种基于ElGamal加密算法的两方秘密分享转换方案,并应用其构建了一个基于国密SM9的门限签名方案。为证明方案的安全性,构建了基于标识的门限签名理想函数,并在通用可组合(universally composable,UC)模型下证明了该方案的安全性。理论分析和实验结果表明,与现有方案相比,提出的门限签名方案在基于ElGamal算法的秘密分享转换方案下效率更高。特别地,当门限值为100时,速度约为基于Paillier方案的6.1倍。在以太坊、Hyperledger Fabric和腾讯云服务平台长安链体验网络3个不同的区块链平台上对该门限签名方案进行了测试,实验结果表明方案在区块链场景中具有可行性。 展开更多
关键词 数字签名 门限签名 SM9 UC安全 区块链
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In an Ocean or a River:Bilinear Auto-Backlund Transformations and Similarity Reductions on an Extended Time-Dependent(3+1)-Dimensional Shallow Water Wave Equation 被引量:1
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作者 GAO Xin-yi 《China Ocean Engineering》 2025年第1期160-165,共6页
With respect to oceanic fluid dynamics,certain models have appeared,e.g.,an extended time-dependent(3+1)-dimensional shallow water wave equation in an ocean or a river,which we investigate in this paper.Using symbolic... With respect to oceanic fluid dynamics,certain models have appeared,e.g.,an extended time-dependent(3+1)-dimensional shallow water wave equation in an ocean or a river,which we investigate in this paper.Using symbolic computation,we find out,on one hand,a set of bilinear auto-Backlund transformations,which could connect certain solutions of that equation with other solutions of that equation itself,and on the other hand,a set of similarity reductions,which could go from that equation to a known ordinary differential equation.The results in this paper depend on all the oceanic variable coefficients in that equation. 展开更多
关键词 OCEAN RIVER extended time-dependent(3+1)-dimensional shallow water wave equation bilinear auto-Bäcklund transformation similarity reduction symbolic computation
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血清c-Myc、SOX9与胃癌病情进展程度的 相关性及对患者不良预后的预测价值
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作者 韩闪 吴珊珊 张巍巍 《淮海医药》 2026年第1期16-20,共5页
目的:分析血清髓细胞增生原癌基因(c-Myc)、性别决定区Y框蛋白9(SOX9)与胃癌病情进展程度的相关性及对患者不良预后的预测价值。方法:选取南阳市第一人民医院2022年3月—2023年6月收治的200例胃癌患者为研究对象,依据病理分期分为早期组... 目的:分析血清髓细胞增生原癌基因(c-Myc)、性别决定区Y框蛋白9(SOX9)与胃癌病情进展程度的相关性及对患者不良预后的预测价值。方法:选取南阳市第一人民医院2022年3月—2023年6月收治的200例胃癌患者为研究对象,依据病理分期分为早期组(50例)和中晚期组(150例),比较2组血清c-Myc、SOX9水平,以及肿瘤标志物[癌胚抗原(CEA)、糖类抗原724(CA724)、CA125、组织多肽特异抗原(TSP)]水平和肿瘤细胞增殖、凋亡情况[肿瘤细胞增殖指数(Ki-67)、细胞凋亡调节因子(Bax)、B细胞淋巴瘤-2(Bcl-2)]。根据术后2年内有无病情复发或病灶转移分为预后不良组(60例)和预后良好组(140例),比较2组血清c-Myc、SOX9水平。采用Pearson系数分析血清c-Myc、SOX9与胃癌病情进展程度指标的相关性,绘制ROC曲线分析血清c-Myc、SOX9对患者不良预后的预测价值。结果:中晚期组血清c-Myc、SOX9水平分别为(1.16±0.41)μg/L、(75.23±10.44)ng/mL,高于早期组的(0.62±0.11)μg/L、(70.32±10.37)ng/mL,差异有统计学意义(P<0.05)。中晚期组Ki-67、Bcl-2高于早期组,Bax低于早期组,差异有统计学意义(P<0.05)。中晚期组血清CEA、CA724、CA125、TSP水平高于早期组,差异有统计学意义(P<0.05)。相关性分析显示,血清c-Myc、SOX9与Ki-67、Bcl-2、CEA、CA724、CA125、TSP呈正相关,与Bax呈负相关(P<0.05)。预后不良组血清c-Myc、SOX9水平分别为(1.31±0.45)μg/L、(78.33±10.27)ng/mL,高于预后良好组的(0.71±0.14)μg/L、(72.28±10.46)ng/mL,差异有统计学意义(P<0.05)。血清c-Myc、SOX9预测胃癌患者发生不良预后的AUC为0.856、0.854,二者联合预测的AUC为0.905,灵敏度为84.12%,特异度为80.39%。结论:血清c-Myc、SOX9与胃癌患者病情进展程度呈正相关,联合检测能实现对患者不良预后的早期预测。 展开更多
关键词 胃肿瘤 髓细胞增生原癌基因 性别决定区Y框蛋白9 病情进展 不良预后
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A 3-Dimensional Cargo Loading Algorithm for the Conveyor-Type Loading System
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作者 Hyeonbin Jeong Young Tae Ryu +1 位作者 Byung Duk Song Sang-Duck Lee 《Computer Modeling in Engineering & Sciences》 2025年第3期2739-2769,共31页
This paper proposes a novel cargo loading algorithm applicable to automated conveyor-type loading systems.The algorithm offers improvements in computational efficiency and robustness by utilizing the concept of discre... This paper proposes a novel cargo loading algorithm applicable to automated conveyor-type loading systems.The algorithm offers improvements in computational efficiency and robustness by utilizing the concept of discrete derivatives and introducing logistics-related constraints.Optional consideration of the rotation of the cargoes was made to further enhance the optimality of the solutions,if possible to be physically implemented.Evaluation metrics were developed for accurate evaluation and enhancement of the algorithm’s ability to efficiently utilize the loading space and provide a high level of dynamic stability.Experimental results demonstrate the extensive robustness of the proposed algorithm to the diversity of cargoes present in Business-to-Consumer environments.This study contributes practical advancements in both cargo loading optimization and automation of the logistics industry,with potential applications in last-mile delivery services,warehousing,and supply chain management. 展开更多
关键词 3-dimensional loading automated loading system B2C logistics cargo loading algorithm conveyortype loading
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白内障病人血清和房水C1q/肿瘤坏死因子相关蛋白9、克老素水平及与炎症因子的相关性
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作者 梁俊荣 戴超 +2 位作者 席海杰 苏金凤 韩鹏飞 《安徽医药》 2026年第1期140-144,共5页
目的分析白内障病人血清和房水C1q/肿瘤坏死因子相关蛋白9(CTRP9)和克老素的表达水平以及与炎症因子的相关性。方法选取2021年12月至2023年5月山西爱尔眼科医院收治的白内障病人100例为研究对象(试验组),另选取同一时期在该院行有晶状... 目的分析白内障病人血清和房水C1q/肿瘤坏死因子相关蛋白9(CTRP9)和克老素的表达水平以及与炎症因子的相关性。方法选取2021年12月至2023年5月山西爱尔眼科医院收治的白内障病人100例为研究对象(试验组),另选取同一时期在该院行有晶状体眼后房型人工晶状体(ICL)植入手术的病人100例作为对照组;采用酶联免疫吸附分析(ELISA)检测血清和房水中CTRP9、克老素表达水平;采用Pearson相关分析白内障病人血清和房水CTRP9、克老素表达水平与炎症因子的相关性;采用多因素logistic回归分析影响白内障发生的因素。结果试验组血清中CTRP9、克老素表达水平均低于对照组[(90.94±30.08)ng/L比(134.59±41.86)ng/L、(39.53±12.89)µg/L比(56.32±17.67)µg/L,P<0.05];试验组房水中CTRP9、克老素表达水平均低于对照组[(101.58±33.08)ng/L比(148.22±47.76)ng/L、(50.48±15.64)µg/L比(65.07±20.33)µg/L,P<0.05];试验组血清中hs-CRP、IL-6、IL-1β和TNF-α表达水平均高于对照组(P<0.05);Pearson相关分析结果显示,试验组血清和房水中CTRP9、克老素表达水平与hs-CRP、IL-6、IL-1β和TNF-α水平均呈负相关(P<0.001);多因素logistic回归分析结果显示,CTRP9、克老素和TNF-α是影响白内障发生的危险因素。结论白内障病人血清和房水中CTRP9、克老素表达水平下降,与炎症因子水平呈负相关。 展开更多
关键词 白内障 房水 C1q/肿瘤坏死因子相关蛋白9 克老素 炎症因子 后房型人工晶状体
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Three-dimensionally interconnected Co9S8/MWCNTs composite cathode host for lithium–sulfur batteries 被引量:3
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作者 Shengyu Zhao Xiaohui Tian +2 位作者 Yingke Zhou Ben Ma Angulakshmi Natarajan 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2020年第7期22-29,I0002,共9页
Several challenging issues,such as the poor conductivity of sulfur,shuttle effects,large volume change of cathode,and the dendritic lithium in anode,have led to the low utilization of sulfur and hampered the commercia... Several challenging issues,such as the poor conductivity of sulfur,shuttle effects,large volume change of cathode,and the dendritic lithium in anode,have led to the low utilization of sulfur and hampered the commercialization of lithium–sulfur batteries.In this study,a novel three-dimensionally interconnected network structure comprising Co9 S8 and multiwalled carbon nanotubes(MWCNTs)was synthesized by a solvothermal route and used as the sulfur host.The assembled batteries delivered a specific capacity of1154 m Ah g-1 at 0.1 C,and the retention was 64%after 400 cycles at 0.5 C.The polar and catalytic Co9 S8 nanoparticles have a strong adsorbent effect for polysulfide,which can effectively reduce the shuttling effect.Meanwhile,the three-dimensionally interconnected CNT networks improve the overall conductivity and increase the contact with the electrolyte,thus enhancing the transport of electrons and Li ions.Polysulfide adsorption is greatly increased with the synergistic effect of polar Co9 S8 and MWCNTs in the three-dimensionally interconnected composites,which contributes to their promising performance for the lithium–sulfur batteries. 展开更多
关键词 Three-dimensional network structure MWCNTS Polar and catalytic Co9S8 Lithium–sulfur batteries
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2.5-dimensional Voronoi numerical simulation method for migration of direct roof in a longwall face
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作者 Bin Yu Yong Li +2 位作者 Yang Tai Weibing Zhu Wenyang Zhang 《Journal of Rock Mechanics and Geotechnical Engineering》 2025年第9期5560-5579,共20页
The fracture and migration patterns of direct roofs play a critical role in excavation stability and mining pressure.However,current methods fail to capture the irregular three-dimensional(3D)behavior of these roofs.I... The fracture and migration patterns of direct roofs play a critical role in excavation stability and mining pressure.However,current methods fail to capture the irregular three-dimensional(3D)behavior of these roofs.In this study,the problem was solved by introducing an innovative 2.5-dimensional(2.5D)Voronoi numerical simulation method,dividing rock layers into 2.5D Voronoi blocks and developing cohesive element-based failure models,supported by a strain-softening HoekeBrown model.The method was applied to the 8311 working face in the Taishan Mine in China,and its accuracy was confirmed through physical experiments.The following conclusions were drawn.The first roof break typically followed an"O-X"pattern.The direct roof did not break randomly over time;instead,it followed three distinct scenarios:(1)A complete break of the direct roof occurred,followed by a sequential collapse(ScenarioⅠ).(2)Regional irregular stacking in one area was followed by sequential collapse in other zones(ScenarioⅡ).(3)The staged breakdown of the direct roof led to separate and sequential collapses on the left and right flanks(ScenarioⅢ).Scenario I was quite common during the 400 m advance of the working face and occurred five times.The fracture characteristics in Scenario I led to widespread pressure on the hydraulic supports in the middle of the working face.Finally,the direct roof from the working face towards the goaf area underwent phases of overhanging,hinging,and collapsing plates.After the first and periodic breaks,the basic roof formed stable hinged plate structures reinforced by overhanging plates and irregular accumulations of the direct roof. 展开更多
关键词 2.5-dimensional(2.5D)Voronoi Direct roof Migration law Longwall face
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Abundant invariant solutions of(3+1)-dimensional combined pKP-BKP equation
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作者 Hengchun Hu Xu Xu 《Chinese Physics B》 2025年第3期291-299,共9页
Lie symmetry analysis is applied to a(3+1)-dimensional combined potential Kadomtsev-Petviashvili equation with B-type Kadomtsev-Petviashvili equation(pKP-BKP equation)and the corresponding similarity reduction equatio... Lie symmetry analysis is applied to a(3+1)-dimensional combined potential Kadomtsev-Petviashvili equation with B-type Kadomtsev-Petviashvili equation(pKP-BKP equation)and the corresponding similarity reduction equations are obtained with the different infinitesimal generators.Invariant solutions with arbitrary functions and constants for the(3+1)-dimensional pKP-BKP equation,including the lump solution,the periodic-lump solution,the two-kink solution,the breather solution and the lump-two-kink solution,have been studied analytically and graphically. 展开更多
关键词 (3+1)-dimensional combined pKP-BKP equation Lie symmetry invariant solutions
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New types of nondegenerate solitons for a(2+1)-dimensional coupled system
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作者 Yong Meng Hafiz Wajahat Ahmed Riaz Ji Lin 《Communications in Theoretical Physics》 2025年第9期1-9,共9页
In this paper,we investigate the(2+1)-dimensional three-component long-wave-short-wave resonance interaction system,which describes complex systems and nonlinear wave phenomena in physics.By employing the Hirota bilin... In this paper,we investigate the(2+1)-dimensional three-component long-wave-short-wave resonance interaction system,which describes complex systems and nonlinear wave phenomena in physics.By employing the Hirota bilinear method,we derive the general nondegenerate N-soliton solution of the system,where each short-wave component contains N arbitrary functions of the independent variable y.The presence of these arbitrary functions in the analytical solution enables the construction of a wide range of nondegenerate soliton types.Finally,we illustrate the structural features of several novel nondegenerate solitons,including M-shaped,multiple double-hump,and sawtooth double-striped solitons,as well as interactions between nondegenerate solitons,such as dromion-like solitons and solitoffs,with the aid of figures. 展开更多
关键词 (2+1)-dimensional coupled system general nondegenerate N-soliton solution arbitrary functions modulation waveform
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NONLINEAR WAVE TRANSITIONS AND THEIR MECHANISMS OF THE(2+1)-DIMENSIONAL KORTEWEG-DE VRIES-SAWADA-KOTERA-RAMANI EQUATION
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作者 Haolin WANG Shoufu TIAN Tiantian ZHANG 《Acta Mathematica Scientia》 2025年第4期1405-1437,共33页
In this work,we study wave state transitions of the(2+1)-dimensional Kortewegde Vries-Sawada-Kotera-Ramani(2KdVSKR)equation by analyzing the characteristic line and phase shift.By converting the wave parameters of the... In this work,we study wave state transitions of the(2+1)-dimensional Kortewegde Vries-Sawada-Kotera-Ramani(2KdVSKR)equation by analyzing the characteristic line and phase shift.By converting the wave parameters of the N-soliton solution into complex numbers,the breath wave solution is constructed.The lump wave solution is derived through the long wave limit method.Then,by choosing appropriate parameter values,we acquire a number of transformed nonlinear waves whose gradient relation is discussed according to the ratio of the wave parameters.Furthermore,we reveal transition mechanisms of the waves by exploring the nonlinear superposition of the solitary and periodic wave components.Subsequently,locality,oscillation properties and evolutionary phenomenon of the transformed waves are presented.And we also prove the change in the geometrical properties of the characteristic lines leads to the phenomena of wave evolution.Finally,for higher-order waves,a range of interaction models are depicted along with their evolutionary phenomena.And we demonstrate that their diversity is due to the fact that the solitary and periodic wave components produce different phase shifts caused by time evolution and collisions. 展开更多
关键词 the(2+1)-dimensional Korteweg-de Vries-Sawada-Kotera-Ramani equation characteristic line transformed nonlinear waves phase shift collision
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Open-Ocean Shallow-Water Dynamics via a(2+1)-Dimensional Generalized Variable-Coefficient Hirota-Satsuma-Ito System: Oceanic Auto-B?cklund Transformation and Oceanic Solitons
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作者 GAO Xin-yi 《China Ocean Engineering》 2025年第3期541-547,共7页
Recently, during the investigations on planetary oceans, Hirota-Satsuma-Ito-type models have been developed. In this paper, for a(2+1)-dimensional generalized variable-coefficient Hirota-Satsuma-Ito system describing ... Recently, during the investigations on planetary oceans, Hirota-Satsuma-Ito-type models have been developed. In this paper, for a(2+1)-dimensional generalized variable-coefficient Hirota-Satsuma-Ito system describing the fluid dynamics of shallow-water waves in an open ocean, non-characteristic movable singular manifold and symbolic computation enable an oceanic auto-B?cklund transformation with three sets of the oceanic solitonic solutions. The results rely on the oceanic variable coefficients in that system. Future oceanic observations might detect some nonlinear features predicted in this paper, and relevant oceanographic insights might be expected. 展开更多
关键词 OCEAN shallow water (2+1)-dimensional generalized variable-coefficient Hirota-Satsuma-Ito system singular manifold symbolic computation B?cklund transformation soliton
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Control-Growth and Photocatalytic Activities of Low-Dimensional Bi2Fe4O9 Crystals
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作者 梁少伟 杨晴 《Chinese Journal of Chemical Physics》 SCIE CAS CSCD 2017年第5期566-570,I0002,共6页
Low-dimensional Bi2Fe4O9 nanosheets and microrods have been selectively prepared by a solvothermal method, from which the growth of the Bi2Fe4O9 crystals can be controlled by the variation of reaction conditions. Stru... Low-dimensional Bi2Fe4O9 nanosheets and microrods have been selectively prepared by a solvothermal method, from which the growth of the Bi2Fe4O9 crystals can be controlled by the variation of reaction conditions. Structure determination showed that the nanosheets are mainly exposed by {001} facets while the microrods are exposed by {110} facets. Ab- sorption spectra revealed that there are two bandgaps observed for both nanosheets (at 1.9 and 1.55 eV) and microrods (1.7 and 1.45 eV), and they both would be available for the sunlight photocatalysis e ciently due to the intensive absorption ability in a wide region. Photocatalytic investigation demonstrated that the overall photocatalytic performance of the microrods is prior to that of the nanosheets due to the variation of bandgaps and exposed facets. The present report provides a useful alternative strategy for the controlling growth of nanostructures and/or microcrystals besides the present demonstration of the Bi2Fe4O9 crystals with diflerent bandgaps and facets that would be able to tune the corresponding photocatalytic ability selectively. 展开更多
关键词 Bi2Fe4O9 Nanosheet Microrod Control growth Photocatalyst
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A Two-dimensional Anthracene-9,10-dicarboxylate Zinc(Ⅱ) Coordination Polymer Based on Binuclear [Zn_2Cl_2] Nodes: Synthesis, Characterization and Luminescent Properties 被引量:2
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作者 王军杰 张仁春 +2 位作者 张道军 常泽 章应辉 《Chinese Journal of Structural Chemistry》 SCIE CAS CSCD 2014年第5期695-700,共6页
A two-dimensional(2D) 44 topological ZnⅡ coordination polymer {[Zn2Cl2(L)(4bpy)2]}∞(H2L = anthracene-9,10-dicarboxylic acid, 4bpy = 4,4ˊ-bipyridine) based on binuclear [Zn2Cl2] nodes has been synthesized an... A two-dimensional(2D) 44 topological ZnⅡ coordination polymer {[Zn2Cl2(L)(4bpy)2]}∞(H2L = anthracene-9,10-dicarboxylic acid, 4bpy = 4,4ˊ-bipyridine) based on binuclear [Zn2Cl2] nodes has been synthesized and characterized by IR, elemental analysis, X-ray powder diffraction and single-crystal X-ray diffraction analysis. Moreover, the luminescent properties of the correspon- ding compound have been briefly investigated. 展开更多
关键词 zinc(Ⅱ) coordination polymer anthracene-9 10-dicarboxylic acid binuclear [Zn2Cl2] nodes luminescent properties
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血清CLDN9、TYK2与生长激素型垂体腺瘤病灶侵袭程度 的相关性及对患者不良预后的预测价值
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作者 王二威 杨凤东 《淮海医药》 2026年第1期26-29,35,共5页
目的:探讨血清Claudin9(CLDN9)、酪氨酸激酶2(TYK2)与生长激素型垂体腺瘤(GHPA)病灶侵袭程度的相关性及对患者不良预后的预测价值。方法:回顾性选取某院2022年1月—2023年6月收治的115例GHPA患者为研究对象,依据病理分期分为早期组(35例... 目的:探讨血清Claudin9(CLDN9)、酪氨酸激酶2(TYK2)与生长激素型垂体腺瘤(GHPA)病灶侵袭程度的相关性及对患者不良预后的预测价值。方法:回顾性选取某院2022年1月—2023年6月收治的115例GHPA患者为研究对象,依据病理分期分为早期组(35例)和中晚期组(80例),比较2组血清CLDN9、TYK2,以及肿瘤细胞增殖、凋亡指标[肿瘤细胞增殖指数(Ki-67)、细胞凋亡调节因子(Bax)、B细胞淋巴瘤-2(Bcl-2)]、病灶情况(病灶直径、病灶浸润深度)。采用Person系数分析血清CLDN9、TYK2与病灶侵袭程度指标的相关性,根据术后随访1年是否发生不良预后分为预后不良组(20例)和预后良好组(95例),绘制ROC曲线分析血清CLDN9、TYK2对GHPA患者发生不良预后的预测价值。结果:中晚期组CLDN9相对表达量(2.43±0.25)高于早期组(1.55±0.27),TYK2相对表达量(0.53±0.12)低于早期组(1.05±0.33),差异有统计学意义(P<0.05)。中晚期组病灶直径、病灶浸润深度、Ki-67、Bcl-2高于早期组,Bax低于早期组,差异有统计学意义(P<0.05)。血清CLDN9与病灶直径、病灶浸润深度、Ki-67、Bcl-2呈正相关,与Bax呈负相关;血清TYK2与病灶直径、病灶浸润深度、Ki-67、Bcl-2呈负相关,与Bax呈正相关(P<0.05)。预后不良组血清CLDN9相对表达量高于预后良好组,TYK2相对表达量低于预后良好组,差异有统计学意义(P<0.05)。ROC分析显示,血清CLDN9、TYK2预测GHPA患者发生不良预后的AUC为0.855、0.853,联合预测的AUC为0.920,灵敏度为83.11%,特异度为79.69%。结论:血清CLDN9与GHPA患者病灶直径、病灶浸润深度、Ki-67、Bcl-2呈正相关,与Bax呈负相关,血清TYK2与之相反,联合检测CLDN9、TYK2能实现对患者不良预后的早期预测。 展开更多
关键词 垂体肿瘤 Claudin9 酪氨酸激酶2 病灶侵袭 预后情况
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前蛋白转化酶枯草溶菌素9抑制剂在糖尿病血脂管理的重要性及其肾脏保护潜力
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作者 王葳 范瑛 汪年松 《中国临床医生杂志》 2026年第1期7-10,共4页
糖尿病已成为21世纪全球最重要的公共卫生问题之一,国际糖尿病联盟发布的数据显示全球约有5.37亿成年人患有糖尿病,预计2045年这一数字将增至7亿[1]。糖尿病患者伴随的血脂异常不仅是动脉粥样硬化性心血管疾病(atherosclerotic cardiova... 糖尿病已成为21世纪全球最重要的公共卫生问题之一,国际糖尿病联盟发布的数据显示全球约有5.37亿成年人患有糖尿病,预计2045年这一数字将增至7亿[1]。糖尿病患者伴随的血脂异常不仅是动脉粥样硬化性心血管疾病(atherosclerotic cardiovascular disease,ASCVD)的主要危险因素。 展开更多
关键词 前蛋白转化酶枯草溶菌素9抑制剂 糖尿病 血脂管理 肾脏保护
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血清GDF9、BMP15及CCL18在子宫内膜异位症患者中的表达及其预测复发的价值
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作者 郭天宝 夏敏 张格霞 《临床医学研究与实践》 2026年第1期106-109,共4页
目的探究血清生长分化因子9(GDF9)、骨形态发生蛋白15(BMP15)及趋化因子配体18(CCL18)在子宫内膜异位症患者中的表达及其预测复发的价值。方法选取2020年3月至2022年1月在我院进行诊治的150例子宫内膜异位症患者作为病例组,根据不同痛... 目的探究血清生长分化因子9(GDF9)、骨形态发生蛋白15(BMP15)及趋化因子配体18(CCL18)在子宫内膜异位症患者中的表达及其预测复发的价值。方法选取2020年3月至2022年1月在我院进行诊治的150例子宫内膜异位症患者作为病例组,根据不同痛经程度将其分为轻度组、中度组、重度组;根据患者治疗2年后超声检测结果将其分为未复发组及复发组。同期选取135例健康体检者作为对照组。检测不同组间患者的血清GDF9、BMP15及CCL18水平;分析血清GDF9、BMP15与CCL18水平的相关性;建立受试者工作特征(ROC)曲线分析GDF9、BMP15、CCL18对子宫内膜异位症复发的预测价值。结果与对照组比较,病例组的血清GDF9和BMP15水平降低,CCL18水平升高(P<0.05)。与轻度组相比,中、重度组的血清GDF9、BMP15水平较低,CCL18水平较高(P<0.05);与中度组相比,重度组的血清GDF9、BMP15水平较低,CCL18水平较高(P<0.05)。与未复发组比较,复发组的血清GDF9和BMP15水平降低,CCL18水平升高(P<0.05)。Pearson相关性分析结果显示,血清GDF9、BMP15水平均与CCL18水平呈负相关(P<0.05)。ROC曲线分析结果显示,GDF9、BMP15、CCL18单独及联合预测子宫内膜异位症复发的曲线下面积(AUC)分别为0.779、0.793、0.864、0.942,联合检测的临床价值高于单一指标。结论GDF9、BMP15及CCL18在子宫内膜异位症患者中表达异常,与病情严重程度密切相关,可作为预测子宫内膜异位症复发的潜在生物标志物。 展开更多
关键词 生长分化因子9 骨形态发生蛋白15 趋化因子配体18 子宫内膜异位症 复发
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血清热休克蛋白-70和基质金属蛋白酶-9与食管鳞状细胞癌患者术后复发的相关性
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作者 连欢欢 王金龙 +5 位作者 户安喜 张涛 孔晓煌 韩高杨 张仁锋 魏创业 《新乡医学院学报》 2026年第1期50-55,共6页
目的探讨血清热休克蛋白-70(HSP-70)、基质金属蛋白酶-9(MMP-9)与食管鳞状细胞癌患者术后复发的关系。方法选择2019年1月至2022年8月郑州中心医院胸外科收治的拟接受根治性手术治疗的116例食管鳞状细胞癌患者为研究对象(观察组),另选择... 目的探讨血清热休克蛋白-70(HSP-70)、基质金属蛋白酶-9(MMP-9)与食管鳞状细胞癌患者术后复发的关系。方法选择2019年1月至2022年8月郑州中心医院胸外科收治的拟接受根治性手术治疗的116例食管鳞状细胞癌患者为研究对象(观察组),另选择同期在本院进行体检的116例健康者作为对照组,比较2组患者血清HSP-70、MMP-9水平。根据术后1 a随访期间复发情况,将观察组患者分为复发组(n=48)和未复发组(n=68),比较2组患者术前、出院前、术后3个月、术后6个月血清HSP-70、MMP-9水平及其他临床资料,采用点二列相关性分析各时间点血清HSP-70、MMP-9水平与术后复发的相关性,采用限制性立方样条(RCS)模型分析食管鳞状细胞癌患者术后复发与血清HSP-70、MMP-9水平的剂量反应关系。结果观察组患者术前血清HSP-70、MMP-9水平高于对照组(P<0.05)。复发组与未复发组患者临床资料及术前血清HSP-70、MMP-9水平比较差异无统计学意义(P>0.05)。复发组与未复发组患者出院前、术后3个月、术后6个月血清HSP-70、MMP-9水平均显著低于术前,且复发组患者各时间点血清HSP-70、MMP-9水平显著高于未复发组(P<0.05)。点二列相关性分析显示,出院前、术后3个月、术后6个月血清HSP-70、MMP-9与食管鳞状细胞癌患者术后复发均呈正相关关系(P<0.05)。选择相关性系数最大的出院前时间点数据行RCS分析,结果显示,食管鳞状细胞癌患者术后复发风险与出院前血清HSP-70、MMP-9水平呈非线性剂量反应关系,当出院前血清HSP-70>2.605μg·L^(-1)、MMP-9>91.105μg·L^(-1)时,患者术后复发风险随指标水平升高而增加。结论食管鳞状细胞癌患者血清HSP-70、MMP-9水平与术后复发呈正相关关系,出院前血清HSP-70、MMP-9水平越高,术后复发的可能性越大。 展开更多
关键词 食管鳞状细胞癌 热休克蛋白70 基质金属蛋白酶-9
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