目的探讨转化生长因子TGF-β1+869T/C基因多态性与子痫前期的相关性。方法采用聚合酶链式反应-限制性片段长度多态性(Polymerase Chain Reaction with Restrition Fragment Length Polymophism,PCR-RFLP)技术检测156例子痫前期患者(子...目的探讨转化生长因子TGF-β1+869T/C基因多态性与子痫前期的相关性。方法采用聚合酶链式反应-限制性片段长度多态性(Polymerase Chain Reaction with Restrition Fragment Length Polymophism,PCR-RFLP)技术检测156例子痫前期患者(子痫前期组)和252例正常妊娠健康孕妇(对照组)外周血的TGF-β1+869T/C基因多态性,并对结果进行统计分析。结果 TGF-β1基因+869T/C位点存在CC、CT、TT三种基因型,子痫前期组CC基因型占33.33%,CT基因型占62.18%,TT基因型占4.49%;对照组CC基因型占13.10%,CT基因型占48.41%,TT基因型占38.49%。子痫前期组孕妇CC和CT基因型频率均明显高于对照组(p<0.01,p<0.01);而TT基因型频率则明显低于对照组(p<0.01)。子痫前期组+869T/C位点C等位基因频率(64.42%)明显高于对照组(37.30%),T等位基因频率(35.58%)明显低于对照组(62.7%)。结论 TGF-β1+869T/C基因多态性与子痫前期显著相关。展开更多
This work presents a time-series photometric variability survey of the young open cluster NGC 869.More than 13000 CCD frames in the BV filters were collected on 19 nights between 2014 November 6 and 2014 December 24.I...This work presents a time-series photometric variability survey of the young open cluster NGC 869.More than 13000 CCD frames in the BV filters were collected on 19 nights between 2014 November 6 and 2014 December 24.In a 20’×20’field centered on the cluster,we detected a total of 28 stars showing photometric variability,12 of which are new discoveries.The classifications and memberships of the variable stars are discussed according to the behaviors and periods of the light curves as well as their positions on the H-R diagram.These results conclude that 22 variable stars are probable members of the cluster while six other stars belong to the field star population.They are categorized as 18 pulsating variable stars(fourβCep,seven SPB,oneβCep/SPB,four Be stars,and twoδSct/γDor candidates),seven eclipsing binaries(five EA and two EB)and three unknown type stars.展开更多
文摘目的探讨转化生长因子TGF-β1+869T/C基因多态性与子痫前期的相关性。方法采用聚合酶链式反应-限制性片段长度多态性(Polymerase Chain Reaction with Restrition Fragment Length Polymophism,PCR-RFLP)技术检测156例子痫前期患者(子痫前期组)和252例正常妊娠健康孕妇(对照组)外周血的TGF-β1+869T/C基因多态性,并对结果进行统计分析。结果 TGF-β1基因+869T/C位点存在CC、CT、TT三种基因型,子痫前期组CC基因型占33.33%,CT基因型占62.18%,TT基因型占4.49%;对照组CC基因型占13.10%,CT基因型占48.41%,TT基因型占38.49%。子痫前期组孕妇CC和CT基因型频率均明显高于对照组(p<0.01,p<0.01);而TT基因型频率则明显低于对照组(p<0.01)。子痫前期组+869T/C位点C等位基因频率(64.42%)明显高于对照组(37.30%),T等位基因频率(35.58%)明显低于对照组(62.7%)。结论 TGF-β1+869T/C基因多态性与子痫前期显著相关。
基金supported by the Sichuan Science and Technology Program(Grant No.2020YFSY0034)Fundamental Research Funds of China West Normal University(Grant Nos.17C051,16E016)support from the National Natural Science Foundation of China(No.12073090)。
文摘This work presents a time-series photometric variability survey of the young open cluster NGC 869.More than 13000 CCD frames in the BV filters were collected on 19 nights between 2014 November 6 and 2014 December 24.In a 20’×20’field centered on the cluster,we detected a total of 28 stars showing photometric variability,12 of which are new discoveries.The classifications and memberships of the variable stars are discussed according to the behaviors and periods of the light curves as well as their positions on the H-R diagram.These results conclude that 22 variable stars are probable members of the cluster while six other stars belong to the field star population.They are categorized as 18 pulsating variable stars(fourβCep,seven SPB,oneβCep/SPB,four Be stars,and twoδSct/γDor candidates),seven eclipsing binaries(five EA and two EB)and three unknown type stars.
