Background The prevalence of heart failure(HF)appears to be 1%-2%in adults and increases with age,ranging from approximately 1%in those younger than 50 years to 10%in those older than 70 years.Malnutrition is associat...Background The prevalence of heart failure(HF)appears to be 1%-2%in adults and increases with age,ranging from approximately 1%in those younger than 50 years to 10%in those older than 70 years.Malnutrition is associated with increased mortality and readmission in patients with cardiovascular disease.Triglyceride total cholesterol body weight index(TCBI),which is a new nutritional index,can be used as a useful prognostic index for patients with coronary artery disease or heart failure.The incidence of readmission due to heart failure remains high in patients with heart failure.The purpose of this study was to investigate whether there is a correlation between the TCBI and readmission rate to facilitate the identification of patients with heart failure at high risk of readmission.Methods This study was a retrospective study that included patients with heart failure who were hospitalized at the Zigong Fourth People.s Hospital from December 2016 to June 2019.TCBI=Serum level of triglyceride(TG,mg/dL)×total cholesterol(TC,mg/dL)×body weight(BW,kg)/1000.The 1685 patients were enrolled and divided into three groups as follows according to the tertiles of TCBI:Low TCBI group(TCBI<460,n=562),medium TCBI group(460≤TCBI<806,n=561)and High TCBI group(TCBI≥806,n=562).The endpoint event was the patient.s readmission in 6 months.Multivariate Cox regression analysis was used to assess the independent association between TCBI levels and 6-month readmission rate.The Kaplan-Meier method was used to draw a time-to-event curve.The Log-rank test was used to determine the difference in event rate among the three TCBI groups.Results During 6-month follow-up,a total of 619 patients(36.7%)applied for readmission,and the low TCBI group had the highest 6-month readmission rate(40.9%vs.35.1%vs.34.2%,P=0.039).Kaplan-Meier curves showed the highest readmission rate for patients with low TCBI during the 6-month follow-up(Log-rank test:P=0.044).In the extended multivariate Cox model,the 6-month readmission hazard ratio(HR)for the low TCBI group was stable in all four models(HRs range:1.24-1.26,P<0.05 for all).After adjusted for variables,a 25%higher of 6-month readmission rate could be observed in patients with low TCBI(HR:1.25,95%CI:1.00-1.56,P=0.046).Conclusions TCBI can be used as an objective indicator to assess the nutritional status of patients.In patients with heart failure,there is a correlation between TCBI levels and the 6-month readmission rate.Lower TCBI level is associated with higher 6-month readmission rate.展开更多
A total of 750 six-month follow-up records of myopia treated with excimer laser photorefractive keratectomy (PRK) were analyzed. By 6 months, in group 1 (up to-6.00D, 587 eyes), uncorrected visual acuity was improved ...A total of 750 six-month follow-up records of myopia treated with excimer laser photorefractive keratectomy (PRK) were analyzed. By 6 months, in group 1 (up to-6.00D, 587 eyes), uncorrected visual acuity was improved to 20 / 20 or better in 86.7% of treated eyes and 95.4% fell into the range of refraction of±1.00D. In group 2 (-6.25D to -11.00D, 163 eyes), 74.5% of treated eyes had uncorrected visual acuity of 20 / 20 or better and 89.4% of the eyes were within ±1.00D. The designed predictability of the two groups was the same (P>0.1). The refractive stability from 3 to 6 months between the two groups was not statistically different, and no severe complications were observed in these two groups. The excimer laser PRK for correcting myopia up to -11.00D appears to be effective, predictable, stable and safe in this study. The ideal outcome may result from the precise ablation quality of excimer laser, its computerized surgical manipulation and an appropriate postoperative management including detection of refractive indices by conical topography and modulation by steroid.展开更多
基金supported by the Natural Science Foundation of Guangdong Province(No.2016A030313858)the Open Cardiology Project of Guangzhou Medical University(No.06-410-2107194)。
文摘Background The prevalence of heart failure(HF)appears to be 1%-2%in adults and increases with age,ranging from approximately 1%in those younger than 50 years to 10%in those older than 70 years.Malnutrition is associated with increased mortality and readmission in patients with cardiovascular disease.Triglyceride total cholesterol body weight index(TCBI),which is a new nutritional index,can be used as a useful prognostic index for patients with coronary artery disease or heart failure.The incidence of readmission due to heart failure remains high in patients with heart failure.The purpose of this study was to investigate whether there is a correlation between the TCBI and readmission rate to facilitate the identification of patients with heart failure at high risk of readmission.Methods This study was a retrospective study that included patients with heart failure who were hospitalized at the Zigong Fourth People.s Hospital from December 2016 to June 2019.TCBI=Serum level of triglyceride(TG,mg/dL)×total cholesterol(TC,mg/dL)×body weight(BW,kg)/1000.The 1685 patients were enrolled and divided into three groups as follows according to the tertiles of TCBI:Low TCBI group(TCBI<460,n=562),medium TCBI group(460≤TCBI<806,n=561)and High TCBI group(TCBI≥806,n=562).The endpoint event was the patient.s readmission in 6 months.Multivariate Cox regression analysis was used to assess the independent association between TCBI levels and 6-month readmission rate.The Kaplan-Meier method was used to draw a time-to-event curve.The Log-rank test was used to determine the difference in event rate among the three TCBI groups.Results During 6-month follow-up,a total of 619 patients(36.7%)applied for readmission,and the low TCBI group had the highest 6-month readmission rate(40.9%vs.35.1%vs.34.2%,P=0.039).Kaplan-Meier curves showed the highest readmission rate for patients with low TCBI during the 6-month follow-up(Log-rank test:P=0.044).In the extended multivariate Cox model,the 6-month readmission hazard ratio(HR)for the low TCBI group was stable in all four models(HRs range:1.24-1.26,P<0.05 for all).After adjusted for variables,a 25%higher of 6-month readmission rate could be observed in patients with low TCBI(HR:1.25,95%CI:1.00-1.56,P=0.046).Conclusions TCBI can be used as an objective indicator to assess the nutritional status of patients.In patients with heart failure,there is a correlation between TCBI levels and the 6-month readmission rate.Lower TCBI level is associated with higher 6-month readmission rate.
文摘A total of 750 six-month follow-up records of myopia treated with excimer laser photorefractive keratectomy (PRK) were analyzed. By 6 months, in group 1 (up to-6.00D, 587 eyes), uncorrected visual acuity was improved to 20 / 20 or better in 86.7% of treated eyes and 95.4% fell into the range of refraction of±1.00D. In group 2 (-6.25D to -11.00D, 163 eyes), 74.5% of treated eyes had uncorrected visual acuity of 20 / 20 or better and 89.4% of the eyes were within ±1.00D. The designed predictability of the two groups was the same (P>0.1). The refractive stability from 3 to 6 months between the two groups was not statistically different, and no severe complications were observed in these two groups. The excimer laser PRK for correcting myopia up to -11.00D appears to be effective, predictable, stable and safe in this study. The ideal outcome may result from the precise ablation quality of excimer laser, its computerized surgical manipulation and an appropriate postoperative management including detection of refractive indices by conical topography and modulation by steroid.
