In this paper, we briefly go over the homogeneous 5D model field theory: from the 5D space-time inception, to its quantum field solutions given in terms of Higgs vacuum, filled with magnetic monopole bose fields of al...In this paper, we briefly go over the homogeneous 5D model field theory: from the 5D space-time inception, to its quantum field solutions given in terms of Higgs vacuum, filled with magnetic monopole bose fields of all energies. Then through the space dimension reduction projections, the Gell-Mann standard model was obtained as well as a quantum to Classical connection was made via introducing Bose distribution to the monopoles to obtain the Perelman entropy and Ricci Flow mappings. This provided us a picture to the creation of Astronomical objects, from galaxies to stars and planets. This method of splitting the monopole energy into ranges is extended to show that below the basic rest mass range of the electron and Quark, it still can be applied to explaining for the creation of the chemical elements periodic table. But perhaps the most interesting is in the lowest hundreds of Hz energy range, obtained from yet another 3 fold space symmetry breaking, into 2D × 1D, producing bio nitrogenous bases composed of 3 Carbon 12 in hexagon structures, due to preservation of the 1D monopole standing waves of this low frequencies. From that by imposing gauge changes the monopole states into DNA spectra. Since such spectra states retain the DLRO, it induces formation of charge carriers periodicity in a spherical bio cell.. It was then argued that due to cell’s surface proteins, the structure must contain partial filled VB, with “p” state hole density, and empty CB, separated from VB by a positive band gap. Such band structures resemble known HTC Cuprate ceramics. Since the HTC goes through a Superconductivity transition via the simultaneous bose exciton condensation, providing a Coulomb pressure, which reduces the band gap substantially, and induces the ODLRO transition of the hole density. The same obviously applies to the bio cells. Because of the near continuous exciton levels generated, a matching to the DNA spectra then can always occur by selective choices of proteins on the cell surface. Judging from a numerical study, we did years ago on YBCO, with doping. We found with a large enough VB hole density, the exciton induced superconducting gap can easily lead to <em>T</em><em>c</em> in the room temperature range. In fact by EMF excitation can increase the exciton pressure and trigger the ODLRO transition <em>T</em><em>c</em> upward. In fact, numerical results then suggest there do exist coherent EMF spectra from three key elements: Water, Carbon and Hydrogen, together with Oxygen, as studied over the years by numerous people, starting from Schr<span style="white-space:nowrap;">ö</span>dinger to most recently Geesink.展开更多
Previously the 5D homogeneous space-time metric was introduced with explicitly given projection operators in matrix form which map the 5D space-time manifold into a Lorentzian space-time. Based on this projection mode...Previously the 5D homogeneous space-time metric was introduced with explicitly given projection operators in matrix form which map the 5D space-time manifold into a Lorentzian space-time. Based on this projection model, vector field and spinor solutions are found to be expressible in terms of SU(2)xL and SU(3)xL, where L is the 4D Lorentz space-time group. The spinor solutions give the SU(2) leptonic states arising from space-time projection, whereas the SU(3) representation arises from conformal projection and gives the quarks, and due to gauge requirement leads to mesons and baryons. This process of mapping the 5D space-time manifold into the 4D space-time is at the basis of an analysis of the recent CERN experimental results, the presence of neutrino oscillations and the observed 125 GeV resonance in the p-p collisions, respectively. In fact, it is found that the spinor solution contains an oscillating phase, and the 125 GeV resonance is shown to be predictable, thereby 1) eliminating the need to introduce a Higgs vacuum, and 2) can be shown possibly to be an indicator for a missing heavy baryon octet.展开更多
5D Space-Time-Energy World-Universe Model is a unified model of the World built around the concept of Medium, composed of massive particles (protons, electrons, photons, neutrinos, and dark matter particles). The Mode...5D Space-Time-Energy World-Universe Model is a unified model of the World built around the concept of Medium, composed of massive particles (protons, electrons, photons, neutrinos, and dark matter particles). The Model provides a mathematical framework that enables precise calculation of medium-bound physical parameters: Hubble’s parameter, intergalactic plasma parameters, temperature of microwave background radiation and the rest mass of photons. This paper aligns the World-Universe Model (WUM) with the theoretical framework developed by Prof. P. S. Wesson, albeit assigning a new physical meaning to the fifth coordinate. In the World-Universe Model, the fifth dimension is associated with the total energy of the Medium of the World, and the gravitomagnetic parameter of the Medium serves as the dimension-transposing parameter.展开更多
当前我国儿童体力活动不足现象日趋显著。为进一步明确建成环境与儿童体力活动间的量化关系,本文基于现有相关文献开展了系统性Meta分析,探讨建成环境“5D”要素对儿童体力活动的影响。在PubMed、Web of Science、Active Living Researc...当前我国儿童体力活动不足现象日趋显著。为进一步明确建成环境与儿童体力活动间的量化关系,本文基于现有相关文献开展了系统性Meta分析,探讨建成环境“5D”要素对儿童体力活动的影响。在PubMed、Web of Science、Active Living Research以及中国知网等电子文献数据库中进行文献检索,检索期限为2010—2023年,采用JBI质量评价工具与Combie横断面研究评价工具的组合工具对纳入文献质量进行评价。采用Meta分析法对文献进行分析与合并。结果表明:建成环境的密度要素、多样性要素与部分设计要素(道路设计、街道连通性)与儿童体力活动无关联性;其他要素均为正向关联性且合并效应量数值基本相同,从大到小依次为公共交通距离要素、设计要素(各二级要素合并)、目的地可达性要素。因此得出以下结论:建成环境与儿童体力活动密切相关;在健康中国和全民健身的战略背景下,通过关注建筑环境中的特定因素,城市规划者可以创造出更适合体育活动的社区空间,促进中国儿童体力活动水平的提高,增强儿童体质。本研究结果将为促进健康行为的建成环境规划建设提供理论依据和数据支撑。展开更多
嵌合抗原受体T细胞(chimeric antigen receptor T cells,CAR-T)的出现使得多发性骨髓瘤(multiple myeloma,MM)患者的治疗进入了一个新的阶段,但大多数患者都难逃原发耐药或疾病复发的不良结局。G蛋白偶联受体C类5组成员D(G protein-coup...嵌合抗原受体T细胞(chimeric antigen receptor T cells,CAR-T)的出现使得多发性骨髓瘤(multiple myeloma,MM)患者的治疗进入了一个新的阶段,但大多数患者都难逃原发耐药或疾病复发的不良结局。G蛋白偶联受体C类5组成员D(G protein-coupled receptor class C group 5 member D,GPRC5D)是目前MM患者的一个有前景的治疗靶点,与GPRC5D CAR-T相关的Ⅰ期临床研究也都显示出较高的反应率和疗效。文章将对现有的靶向GPRC5D CAR-T细胞最新研究进行综述,旨在通过总结讨论目前不同GPRC5D CAR-T细胞治疗复发难治性MM的研究现状,对今后的临床治疗提供更多参考。展开更多
近十年来,在建筑行业中建筑信息模型(building information modeling,BIM)5D的应用和研究越来越多,在传统建筑工程项目管理上得到了极大的发展。然而,基于BIM5D的传统建筑设计、施工管理、成本控制等领域的研究较多,但在装配式建筑领域B...近十年来,在建筑行业中建筑信息模型(building information modeling,BIM)5D的应用和研究越来越多,在传统建筑工程项目管理上得到了极大的发展。然而,基于BIM5D的传统建筑设计、施工管理、成本控制等领域的研究较多,但在装配式建筑领域BIM5D的应用研究有限。因此,回顾分析了相关的文献综述,归纳总结了BIM5D在装配式建筑工程管理中政策方面、技术方面、人才方面、使用成本方面等影响因素,填补了文献空白,进而推进BIM5D技术在装配式建筑工程管理中的应用,促进装配式建筑在建筑行业的发展。展开更多
文摘In this paper, we briefly go over the homogeneous 5D model field theory: from the 5D space-time inception, to its quantum field solutions given in terms of Higgs vacuum, filled with magnetic monopole bose fields of all energies. Then through the space dimension reduction projections, the Gell-Mann standard model was obtained as well as a quantum to Classical connection was made via introducing Bose distribution to the monopoles to obtain the Perelman entropy and Ricci Flow mappings. This provided us a picture to the creation of Astronomical objects, from galaxies to stars and planets. This method of splitting the monopole energy into ranges is extended to show that below the basic rest mass range of the electron and Quark, it still can be applied to explaining for the creation of the chemical elements periodic table. But perhaps the most interesting is in the lowest hundreds of Hz energy range, obtained from yet another 3 fold space symmetry breaking, into 2D × 1D, producing bio nitrogenous bases composed of 3 Carbon 12 in hexagon structures, due to preservation of the 1D monopole standing waves of this low frequencies. From that by imposing gauge changes the monopole states into DNA spectra. Since such spectra states retain the DLRO, it induces formation of charge carriers periodicity in a spherical bio cell.. It was then argued that due to cell’s surface proteins, the structure must contain partial filled VB, with “p” state hole density, and empty CB, separated from VB by a positive band gap. Such band structures resemble known HTC Cuprate ceramics. Since the HTC goes through a Superconductivity transition via the simultaneous bose exciton condensation, providing a Coulomb pressure, which reduces the band gap substantially, and induces the ODLRO transition of the hole density. The same obviously applies to the bio cells. Because of the near continuous exciton levels generated, a matching to the DNA spectra then can always occur by selective choices of proteins on the cell surface. Judging from a numerical study, we did years ago on YBCO, with doping. We found with a large enough VB hole density, the exciton induced superconducting gap can easily lead to <em>T</em><em>c</em> in the room temperature range. In fact by EMF excitation can increase the exciton pressure and trigger the ODLRO transition <em>T</em><em>c</em> upward. In fact, numerical results then suggest there do exist coherent EMF spectra from three key elements: Water, Carbon and Hydrogen, together with Oxygen, as studied over the years by numerous people, starting from Schr<span style="white-space:nowrap;">ö</span>dinger to most recently Geesink.
文摘Previously the 5D homogeneous space-time metric was introduced with explicitly given projection operators in matrix form which map the 5D space-time manifold into a Lorentzian space-time. Based on this projection model, vector field and spinor solutions are found to be expressible in terms of SU(2)xL and SU(3)xL, where L is the 4D Lorentz space-time group. The spinor solutions give the SU(2) leptonic states arising from space-time projection, whereas the SU(3) representation arises from conformal projection and gives the quarks, and due to gauge requirement leads to mesons and baryons. This process of mapping the 5D space-time manifold into the 4D space-time is at the basis of an analysis of the recent CERN experimental results, the presence of neutrino oscillations and the observed 125 GeV resonance in the p-p collisions, respectively. In fact, it is found that the spinor solution contains an oscillating phase, and the 125 GeV resonance is shown to be predictable, thereby 1) eliminating the need to introduce a Higgs vacuum, and 2) can be shown possibly to be an indicator for a missing heavy baryon octet.
文摘5D Space-Time-Energy World-Universe Model is a unified model of the World built around the concept of Medium, composed of massive particles (protons, electrons, photons, neutrinos, and dark matter particles). The Model provides a mathematical framework that enables precise calculation of medium-bound physical parameters: Hubble’s parameter, intergalactic plasma parameters, temperature of microwave background radiation and the rest mass of photons. This paper aligns the World-Universe Model (WUM) with the theoretical framework developed by Prof. P. S. Wesson, albeit assigning a new physical meaning to the fifth coordinate. In the World-Universe Model, the fifth dimension is associated with the total energy of the Medium of the World, and the gravitomagnetic parameter of the Medium serves as the dimension-transposing parameter.
文摘当前我国儿童体力活动不足现象日趋显著。为进一步明确建成环境与儿童体力活动间的量化关系,本文基于现有相关文献开展了系统性Meta分析,探讨建成环境“5D”要素对儿童体力活动的影响。在PubMed、Web of Science、Active Living Research以及中国知网等电子文献数据库中进行文献检索,检索期限为2010—2023年,采用JBI质量评价工具与Combie横断面研究评价工具的组合工具对纳入文献质量进行评价。采用Meta分析法对文献进行分析与合并。结果表明:建成环境的密度要素、多样性要素与部分设计要素(道路设计、街道连通性)与儿童体力活动无关联性;其他要素均为正向关联性且合并效应量数值基本相同,从大到小依次为公共交通距离要素、设计要素(各二级要素合并)、目的地可达性要素。因此得出以下结论:建成环境与儿童体力活动密切相关;在健康中国和全民健身的战略背景下,通过关注建筑环境中的特定因素,城市规划者可以创造出更适合体育活动的社区空间,促进中国儿童体力活动水平的提高,增强儿童体质。本研究结果将为促进健康行为的建成环境规划建设提供理论依据和数据支撑。
文摘嵌合抗原受体T细胞(chimeric antigen receptor T cells,CAR-T)的出现使得多发性骨髓瘤(multiple myeloma,MM)患者的治疗进入了一个新的阶段,但大多数患者都难逃原发耐药或疾病复发的不良结局。G蛋白偶联受体C类5组成员D(G protein-coupled receptor class C group 5 member D,GPRC5D)是目前MM患者的一个有前景的治疗靶点,与GPRC5D CAR-T相关的Ⅰ期临床研究也都显示出较高的反应率和疗效。文章将对现有的靶向GPRC5D CAR-T细胞最新研究进行综述,旨在通过总结讨论目前不同GPRC5D CAR-T细胞治疗复发难治性MM的研究现状,对今后的临床治疗提供更多参考。
文摘近十年来,在建筑行业中建筑信息模型(building information modeling,BIM)5D的应用和研究越来越多,在传统建筑工程项目管理上得到了极大的发展。然而,基于BIM5D的传统建筑设计、施工管理、成本控制等领域的研究较多,但在装配式建筑领域BIM5D的应用研究有限。因此,回顾分析了相关的文献综述,归纳总结了BIM5D在装配式建筑工程管理中政策方面、技术方面、人才方面、使用成本方面等影响因素,填补了文献空白,进而推进BIM5D技术在装配式建筑工程管理中的应用,促进装配式建筑在建筑行业的发展。
