A new barium aluminoborate, Ba2Al4B6O17, has been synthesized by the hightemperature solution reaction at 780 ℃. The single-crystal XRD analysis shows that it crystallizes in triclinic space group P■ with a = 8.9601...A new barium aluminoborate, Ba2Al4B6O17, has been synthesized by the hightemperature solution reaction at 780 ℃. The single-crystal XRD analysis shows that it crystallizes in triclinic space group P■ with a = 8.9601(5), b = 9.1835(6), c = 10.6574(7) ?, a = 95.050(6)°, b = 111.569(5)°, g = 90.280(6)°, V = 811.71(9) ?3, Z = 2, Mr = 719.46, Dc = 2.944 g/cm3, μ = 5.127 mm-1, F(000) = 660, R = 0.0361 and wR = 0.0855 for 3846 observed reflections and 262 variables. This compound represents a new structure that features a three-dimensional [Al4B6O17]n4n- framework constructed by AlO4 tetrahedra, BO3 triangles, and B2O54-groups composed of two corner-sharing BO3 triangles, with intersecting open channels accommodating Ba2+ cations. It melts incongruently at 849 ℃. The existence of BO3 groups is confirmed by FT-IR and Raman spectra. The insulating nature with an optical band gap of about 3.50 eV is revealed by UV-VIS diffuse reflectance spectrum. Band structure calculations indicate that it is an indirect band material.展开更多
BACKGROUND Major depressive disorder(MDD)is a significant psychiatric condition that poses a serious threat to human life,primarily due to its association with suicidal behavior.The single nucleotide polymorphism rs37...BACKGROUND Major depressive disorder(MDD)is a significant psychiatric condition that poses a serious threat to human life,primarily due to its association with suicidal behavior.The single nucleotide polymorphism rs372369000 is a risk locus for MDD and is located within the B4GALT6 gene.However,the biological and pathological implications of B4GALT6 in the brain concerning MDD remain unclear.AIM To reveal the biological and pathological significance of B4GALT6 in the brain and MDD.METHODS An inflammation-associated depression mouse model was developed by treating mice with lipopolysaccharides.B4GALT6-like immunoreactivity distribution and expression level was examined throughout the brain.RESULTS B4GALT6-like immunoreactivity increased in the hippocampus,PrL,and the visual cortex V1 region of MDD mice.This elevation varied across different brain subregions and cell types.Specifically,pathological alterations in B4GALT6-like immunoreactivity were observed in CA1 microglia,CA2 neurons,CA3 microglia and neurons,as well as V1 microglia and astrocytes.These changes correlated with the pathology of depression.CONCLUSION Although the neuropathological role of B4GALT6 in the brain remains to be fully characterized,B4GALT6 may be a potential therapeutic target for MDD.展开更多
Green-photoluminescence material Zn4B6O13: Ce3+, Tb3+ was first synthesized by spread method of high temperature and solid state reaction, which is cubic crystal system with lattice parameters: a(0) = 0.7472 nm, V = 0...Green-photoluminescence material Zn4B6O13: Ce3+, Tb3+ was first synthesized by spread method of high temperature and solid state reaction, which is cubic crystal system with lattice parameters: a(0) = 0.7472 nm, V = 0.4172 nm(3), and structural properties are investigated by XRD. The excitation and emission band of Ce3+ ion single-doped in Zn4B6O13 transfer longer spectra 2.38 similar to 4.94 kk than in other matrices. Emission band of Ce3+ ion better overlaps with the F-7(6)-->(5)G(2),D-5(1),H-5(7) absorption band of Tb3+. It shows that emission of Tb3+ ion is sensitized by Ce3+. In Zn4B6O13:Ce3+, Tb3+, it is due to the energy transfer mechanism, resonance transfer of electric multipolar interaction of the dipole-dipole between Ce3+-->Ce3+ and Ce3+-->Tb3+. The color coordinates of Zn4B6O13: X 0.281, gamma = 0.619. The mean diameter of the particles is 0.23 mum.展开更多
基金Supported by the National Natural Science Foundation of China(No.20871012)
文摘A new barium aluminoborate, Ba2Al4B6O17, has been synthesized by the hightemperature solution reaction at 780 ℃. The single-crystal XRD analysis shows that it crystallizes in triclinic space group P■ with a = 8.9601(5), b = 9.1835(6), c = 10.6574(7) ?, a = 95.050(6)°, b = 111.569(5)°, g = 90.280(6)°, V = 811.71(9) ?3, Z = 2, Mr = 719.46, Dc = 2.944 g/cm3, μ = 5.127 mm-1, F(000) = 660, R = 0.0361 and wR = 0.0855 for 3846 observed reflections and 262 variables. This compound represents a new structure that features a three-dimensional [Al4B6O17]n4n- framework constructed by AlO4 tetrahedra, BO3 triangles, and B2O54-groups composed of two corner-sharing BO3 triangles, with intersecting open channels accommodating Ba2+ cations. It melts incongruently at 849 ℃. The existence of BO3 groups is confirmed by FT-IR and Raman spectra. The insulating nature with an optical band gap of about 3.50 eV is revealed by UV-VIS diffuse reflectance spectrum. Band structure calculations indicate that it is an indirect band material.
基金Supported by Hunan Provincial Natural Science Foundation of China,No.2025JJ80473 and No.2025JJ80484the Institute of Hospital Management,National Health Commission of China,Major Project,No.SZ2024HL021.
文摘BACKGROUND Major depressive disorder(MDD)is a significant psychiatric condition that poses a serious threat to human life,primarily due to its association with suicidal behavior.The single nucleotide polymorphism rs372369000 is a risk locus for MDD and is located within the B4GALT6 gene.However,the biological and pathological implications of B4GALT6 in the brain concerning MDD remain unclear.AIM To reveal the biological and pathological significance of B4GALT6 in the brain and MDD.METHODS An inflammation-associated depression mouse model was developed by treating mice with lipopolysaccharides.B4GALT6-like immunoreactivity distribution and expression level was examined throughout the brain.RESULTS B4GALT6-like immunoreactivity increased in the hippocampus,PrL,and the visual cortex V1 region of MDD mice.This elevation varied across different brain subregions and cell types.Specifically,pathological alterations in B4GALT6-like immunoreactivity were observed in CA1 microglia,CA2 neurons,CA3 microglia and neurons,as well as V1 microglia and astrocytes.These changes correlated with the pathology of depression.CONCLUSION Although the neuropathological role of B4GALT6 in the brain remains to be fully characterized,B4GALT6 may be a potential therapeutic target for MDD.
文摘Green-photoluminescence material Zn4B6O13: Ce3+, Tb3+ was first synthesized by spread method of high temperature and solid state reaction, which is cubic crystal system with lattice parameters: a(0) = 0.7472 nm, V = 0.4172 nm(3), and structural properties are investigated by XRD. The excitation and emission band of Ce3+ ion single-doped in Zn4B6O13 transfer longer spectra 2.38 similar to 4.94 kk than in other matrices. Emission band of Ce3+ ion better overlaps with the F-7(6)-->(5)G(2),D-5(1),H-5(7) absorption band of Tb3+. It shows that emission of Tb3+ ion is sensitized by Ce3+. In Zn4B6O13:Ce3+, Tb3+, it is due to the energy transfer mechanism, resonance transfer of electric multipolar interaction of the dipole-dipole between Ce3+-->Ce3+ and Ce3+-->Tb3+. The color coordinates of Zn4B6O13: X 0.281, gamma = 0.619. The mean diameter of the particles is 0.23 mum.
