Herein,copper-catalyzed 1,4-protosilylation and 1,4-protoborylation of enynic orthoesters have been developed.The enynic orthoesters as precursors of unstable enynic esters were applied to produce the functionalized 2...Herein,copper-catalyzed 1,4-protosilylation and 1,4-protoborylation of enynic orthoesters have been developed.The enynic orthoesters as precursors of unstable enynic esters were applied to produce the functionalized 2,3-allenoate products.Meanwhile,the asymmetric 1,4-protosilylation of enynic orthoesters with Ph Me2Si-Bpin was also studied.The chiral monopyridine imidazoline ligand was efficient to provide the asymmetric 1,4-protosilylation products with high enantioselectivity.展开更多
基金the funding support of the National Natural Science Foundation of China(No.21871240)the Strategic Priority Research Program of the CAS(No.XDPB14)the Fundamental Research Funds for the Central Universities(No.WK2060190082)。
文摘Herein,copper-catalyzed 1,4-protosilylation and 1,4-protoborylation of enynic orthoesters have been developed.The enynic orthoesters as precursors of unstable enynic esters were applied to produce the functionalized 2,3-allenoate products.Meanwhile,the asymmetric 1,4-protosilylation of enynic orthoesters with Ph Me2Si-Bpin was also studied.The chiral monopyridine imidazoline ligand was efficient to provide the asymmetric 1,4-protosilylation products with high enantioselectivity.
