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Effect of pre-deformation on aging creep of Al-Li-S4 alloy and its constitutive modeling 被引量:9
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作者 王萌 湛利华 +2 位作者 杨有良 阳凌 黄明辉 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2015年第5期1383-1390,共8页
A set of uniaxial tensile creep tests at different pre-deformations, aging temperatures and stress levels were carried out for Al-Li-S4 alloy, and the creep behavior and the effects of pre-deformation on mechanical pr... A set of uniaxial tensile creep tests at different pre-deformations, aging temperatures and stress levels were carried out for Al-Li-S4 alloy, and the creep behavior and the effects of pre-deformation on mechanical properties and microstructures were determined under basic thermodynamics conditions of aging forming. The results show that pre-deformation shortens the time of primary creep and raises the second steady-state creep rate. Then, the total creep strain is greater, but in the range of test parameters it is still smaller than that without pre-deformation. In addition, transmission electron microscopy(TEM) observation shows that pre-deformation promotes the formation of T1 phase and θ′ phase and makes them distribute more dispersively, while inhibits the generation of δ′ phase, which leads to the improvement of mechanical properties of the alloy. A unified constitutive model reflecting the effects of aging mechanism, stress levels and different pre-deformations was established. The fitting results agree with the experimental data well. 展开更多
关键词 Al-Li-S4 alloy aging creep PRE-dEFORMATION mechanical properties microstructure constitutive model
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氮中溴氯甲烷、1,4-二氟苯、氯苯-D5、对溴氟苯混合气体标准物质研制
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作者 李朝锦 王宁 《化学分析计量》 2026年第2期1-7,共7页
以高纯氮、溴氯甲烷、1,4-二氟苯、氯苯-D5、对溴氟苯为原料,采用重量法制备特性量值为1.00μmol/mol的氮中溴氯甲烷、1,4-二氟苯、氯苯-D5、对溴氟苯混合气体标准物质。使用气相色谱-质谱联用仪对制备的气体标准物质的一致性、均匀性... 以高纯氮、溴氯甲烷、1,4-二氟苯、氯苯-D5、对溴氟苯为原料,采用重量法制备特性量值为1.00μmol/mol的氮中溴氯甲烷、1,4-二氟苯、氯苯-D5、对溴氟苯混合气体标准物质。使用气相色谱-质谱联用仪对制备的气体标准物质的一致性、均匀性、稳定性及量值进行了检验和核验。研制的1μmol/mol氮中4组分混合气体标准物质中,所有组分的偏差均在1%以内,不同批次制备的气体具有良好的一致性;组内和组间无显著性系统差异,F检验计算结果均未超过临界值,混合气体均匀性满足要求;相对扩展不确定度为4%(k=2),有效期12个月。该混合气体标准物质均匀性、稳定性符合预期要求。 展开更多
关键词 挥发性有机物 气相色谱-质谱联用仪 溴氯甲烷 1 4-二氟苯 氯苯-d5 对溴氟苯
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Modeling the Interior of Black Holes Utilizing a 4-D Spatial Blackbody Radiation Model with an Exponential Distribution
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作者 Christopher Pilot 《Journal of High Energy Physics, Gravitation and Cosmology》 2019年第3期953-983,共31页
This is a second follow up paper on a model, which treats the black hole as a 4-D spatial ball filled with blackbody radiation. For the interior radiative mass distribution, we employ a new type of truncated probabili... This is a second follow up paper on a model, which treats the black hole as a 4-D spatial ball filled with blackbody radiation. For the interior radiative mass distribution, we employ a new type of truncated probability distribution function, the exponential distribution. We find that this distribution comes closest to reproducing a singularity at the center, and yet it is finite at 4-D radius, . This distribution will give a constant gravitational acceleration for a test particle throughout the black hole, irrespective of radius. The 4-D gravitational acceleration is given by the expression, , where R is the radius of the black hole, MR is its mass, and is the exponential shape parameter, which depends only on the mass, or radius, of the black hole. We calculate the gravitational force, and the entropy within the black hole interior, as well as on its surface, identified as the event horizon, which separates 3-D from 4-D space. Similar to a truncated Gaussian distribution, the gravitational force increases discontinuously, and dramatically, upon entry into the 4-D black hole from the 3-D side. It is also radius dependent within the 4-D black hole. Moreover, the total entropy is shown to be much less than the Bekenstein result, similar to the truncated Gaussian. For the gravitational force, we obtain, , where Mr is the radiative mass enclosed within a 4-D volume of radius r. This unusual force law indicates that the gravitational force acting upon a layer of blackbody photons at radius r is strictly proportional to the enclosed radiative energy, MrC2, contained within that radius, with 0.1λ being the constant of proportionality. For the entropy at radius, r, and on the surface, we obtain an expression which is order of magnitude comparable to the truncated Normal distribution. Tables are presented for three black holes, one having a mass equal to that of the sun. The other two have masses, which are ten times that of the sun, and 106 solar masses. The corresponding parameters are found to equal, , respectively. We compare these results to the truncated Gaussian distribution, which were worked out in another paper. 展开更多
关键词 Black HOLES 4-d SPATIAL BLACKBODY Radiation model EXPONENTIAL Distribution
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Spectroscopic Characterization, Molecular Modeling and DFT/TD-DFT/PCM Calculations of Novel Hydrogen-Bonded Charge Transfer Complex between Chloranilic Acid and 2-Amino-4,6-Dimethylpyridine
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作者 Khairia M. Al-Ahmary Fatimah A. Alshehri +1 位作者 Faten M. Atlam Mohamed K. Awad 《Open Journal of Physical Chemistry》 2020年第1期1-32,共32页
A charge transfer hydrogen bonded complex between the electron donor (proton acceptor) 2-amino-4,6-dimethylpyridine with the electron acceptor (proton donor) chloranilic acid has been synthesized and studied experimen... A charge transfer hydrogen bonded complex between the electron donor (proton acceptor) 2-amino-4,6-dimethylpyridine with the electron acceptor (proton donor) chloranilic acid has been synthesized and studied experimentally and theoretically. The stability constant recorded high values indicating the high stability of the formed complex. In chloroform, ethanol, methanol and acetonitrile were found the stoichiometric ratio 1:1. The solid complex was prepared and characterized by different spectroscopy techniques. FTIR, 1H and 13C NMR studies supported the presence of proton and charge transfers in the formed complex. Complemented with experimental results, molecular modelling using the density functional theory (DFT) calculations was carried out in the gas, chloroform and methanol phases where the existence of charge and hydrogen transfers. Finally, a good consistency between experimental and theoretical calculations was found confirming that the applied basis set is the suitable one for the system under investigation. 展开更多
关键词 2-Amino-4 6-dimethylpyridine Charge Transfer DFT Hydrogen BOND Molecular modelling COMPUTATIONS and Spectroscopy
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基于24Model-D-ISM的地铁站火灾疏散影响因素研究 被引量:2
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作者 孙世梅 张家严 《中国安全科学学报》 CAS CSCD 北大核心 2024年第4期153-159,共7页
为预防地铁站火灾事故,深入了解地铁站火灾人员疏散影响因素间的内在联系与层次结构,基于第6版“2-4”模型(24Model)分析63起地铁站火灾疏散事故,充分考虑各个因素之间的交互作用,提取19个影响地铁站人员疏散的关键因素,建立地铁站火灾... 为预防地铁站火灾事故,深入了解地铁站火灾人员疏散影响因素间的内在联系与层次结构,基于第6版“2-4”模型(24Model)分析63起地铁站火灾疏散事故,充分考虑各个因素之间的交互作用,提取19个影响地铁站人员疏散的关键因素,建立地铁站火灾人员疏散影响因素指标体系;采用算子客观赋权法(C-OWA)改进决策试验与评价实验法(DEMATEL),确定地铁站火灾人员疏散的重要影响因素;在此基础上,采用解释结构模型(ISM)分析各个因素间的层次结构及相互作用路径,构建地铁站火灾人员疏散影响因素的多级递阶结构模型。研究结果表明:疏散引导、恐慌从众行为、人员拥挤为地铁站火灾人员疏散的关键影响因素;地铁站火灾人员疏散受表层因素、中间层因素、深层因素共同作用的影响,其中,疏散教育与培训、设施维护与检查、疏散预案等因素是根源影响因素,重视根源影响因素的改善有利于从本质上预防和控制事故的发生。 展开更多
关键词 “2-4”模型(24model) 决策试验与评价实验法(DEMATEL) 解释结构模型(ISM) 地铁站 火灾疏散 影响因素
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基于24Model的动火作业事故致因文本挖掘 被引量:1
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作者 牛茂辉 李威君 +1 位作者 刘音 王璐 《中国安全科学学报》 北大核心 2025年第3期151-158,共8页
为探究工业动火作业事故的根源,提出一种基于“2-4”模型(24Model)的文本挖掘方法。首先,收集整理220篇动火作业事故报告,并作为数据集,构建基于来自变换器的双向编码器表征量(BERT)的24Model分类器,使用预训练模型训练和评估事故报告... 为探究工业动火作业事故的根源,提出一种基于“2-4”模型(24Model)的文本挖掘方法。首先,收集整理220篇动火作业事故报告,并作为数据集,构建基于来自变换器的双向编码器表征量(BERT)的24Model分类器,使用预训练模型训练和评估事故报告数据集,构建分类模型;然后,通过基于BERT的关键字提取算法(KeyBERT)和词频-逆文档频率(TF-IDF)算法的组合权重,结合24Model框架,建立动火作业事故文本关键词指标体系;最后,通过文本挖掘关键词之间的网络共现关系,分析得到事故致因之间的相互关联。结果显示,基于BERT的24Model分类器模型能够系统准确地判定动火作业事故致因类别,通过组合权重筛选得到4个层级关键词指标体系,其中安全管理体系的权重最大,结合共现网络分析得到动火作业事故的7项关键致因。 展开更多
关键词 “2-4”模型(24model) 动火作业 事故致因 文本挖掘 指标体系
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4-(芳基乙炔基)-吡咯并[2,3-d]嘧啶通过抑制mGluR5调控ERK1/2-SGK1信号通路改善小鼠创伤后应激障碍 被引量:1
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作者 何存宝 杨绍杰 朱国旗 《南方医科大学学报》 北大核心 2025年第4期765-773,共9页
目的评价4-(芳基乙炔基)-吡咯并[2,3-d]嘧啶(10b)对单一长时程应激(SPS)诱导的小鼠创伤后应激障碍(PTSD)样行为及ERK1/2-SGK1信号通路的影响。方法将C57 BL/6小鼠随机分为正常对照组,SPS模型组,化合物10b低、中、高剂量组和帕罗西汀组,6... 目的评价4-(芳基乙炔基)-吡咯并[2,3-d]嘧啶(10b)对单一长时程应激(SPS)诱导的小鼠创伤后应激障碍(PTSD)样行为及ERK1/2-SGK1信号通路的影响。方法将C57 BL/6小鼠随机分为正常对照组,SPS模型组,化合物10b低、中、高剂量组和帕罗西汀组,6只/组。采用行为学实验评价SPS模型组小鼠的PTSD样行为;Western blotting联合免疫荧光检测小鼠海马组织代谢型谷氨酸受体5(mGluR5)、p-ERK、SGK1蛋白表达水平;HE染色检测肝肾组织的病理损伤;分子对接和分子动力学验证化合物10b与mGluR5结合的稳定性。结果与对照组比较,SPS模型组小鼠表现出PTSD样行为(P<0.05),海马mGluR5和p-ERK蛋白表达升高,SGK1蛋白表达减少(P<0.05),而化合物10b可改善SPS组小鼠的行为异常(P<0.05),并抑制mGluR5表达,逆转p-ERK和SGK1的异常(P<0.05),且无明显肝肾毒性;分子对接和分子动力学结果显示10b与mGluR5结合稳定。结论化合物10b能改善SPS诱导的小鼠PTSD样行为,其机制可能和抑制mGluR5调节ERK1/2-SGK1信号通路相关。 展开更多
关键词 4-(芳基乙炔基)-吡咯并[2 3-d]嘧啶 创伤后应激障碍 代谢型谷氨酸受体5 单一长时程应激 ERK1/2 SGK1
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3-D Geological Modeling-Concept,Methods and Key Techniques 被引量:19
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作者 PAN Mao LI Zhaoliang +2 位作者 GAO Zhongbo YANG Yang WU Gengyu 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2012年第4期1031-1036,共6页
3-D geological modeling plays an increasingly important role in Petroleum Geology, Mining Geology and Engineering Geology. The complexity of geological conditions requires different modeling methods in different situa... 3-D geological modeling plays an increasingly important role in Petroleum Geology, Mining Geology and Engineering Geology. The complexity of geological conditions requires different modeling methods in different situations. This paper summarizes the general concept of geological modeling; compares the characteristics of borehole-based modeling, cross-section based modeling and multi- source interactive modeling; analyses key techniques in 3-D geological modeling; and highlights the main difficulties and directions of future studies. 展开更多
关键词 3-d geological modeling geological interpretation methods of modeling quality of models
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Application of 3-D Geoscience Modeling Technology for the Estimation of Solid Mineral Reserves 被引量:17
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作者 PAN Mao LI Jun +1 位作者 WANG Zhangang JIN Jiangjun 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2009年第3期655-660,共6页
Applying new approaches, methods, and technologies for the estimation of reserves can effectively improve the efficiency and accuracy of assessments of solid mineral resources. After analyzing the development of 3-D g... Applying new approaches, methods, and technologies for the estimation of reserves can effectively improve the efficiency and accuracy of assessments of solid mineral resources. After analyzing the development of 3-D geoscience modeling technology (3-D GMT), this paper discusses the application of 3-D GMT for the estimation of solid mineral reserves, emphatically introducing its workflow and two key technologies, 3-D orebody surface modeling, and property modeling. Moreover, the paper analyzes the limitations of traditional methods, such as the section method and geological block method, and points out the advantages of 3-D GMT: building more accurate 3-D orebody models, expressing the internal inhomogeneous attributes of an orebody, reducing the potential for errors in the estimation of reserves, and implementing dynamic estimations of reserves. 展开更多
关键词 3-d geoscience modeling solid mineral resource estimation of reserves surface modeling property modeling
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2,4二氯苯氧乙酸(2,4-D)生产工艺综述 被引量:1
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作者 李浩桤 张华 《山东化工》 2025年第4期131-134,138,共5页
2,4二氯苯氧乙酸是一种广泛应用的化学药品,简称2,4-D(也称2,4-滴或2,4-D酸)。2,4-D可作为生长刺激素,2,4-D钠盐、胺盐及酯类具有高度选择性和内吸作用的除草性能,可作为除草剂。合成2,4-D有先氯化和后氯化两种方法,目前国内基本上都采... 2,4二氯苯氧乙酸是一种广泛应用的化学药品,简称2,4-D(也称2,4-滴或2,4-D酸)。2,4-D可作为生长刺激素,2,4-D钠盐、胺盐及酯类具有高度选择性和内吸作用的除草性能,可作为除草剂。合成2,4-D有先氯化和后氯化两种方法,目前国内基本上都采用先氯化法,其工艺依次为苯酚氯化制备2,4-二氯苯酚、2,4-二氯苯酚精制、酚钠盐制备、氯乙酸钠盐制备、缩合、酸化、干燥及废水处理。分别对各部分工艺进行了简单叙述,并结合国内外文献对生产工艺研究和进展进行了介绍。提出了目前2,4-D生产工艺中最迫切需要解决的问题和研究方向。 展开更多
关键词 2 4-二氯苯氧乙酸钠 2 4-d 氯化 缩合
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2.5-D modeling of cross-hole electromagnetic measurement by nite element method 被引量:3
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作者 Shen Jinsong Sun Wenbo 《Petroleum Science》 SCIE CAS CSCD 2008年第2期126-134,共9页
A finite element method is developed for simulating frequency domain electromagnetic responses due to a dipole source in the 2-D conductive structures. Computing costs are considerably minimized by reducing the full t... A finite element method is developed for simulating frequency domain electromagnetic responses due to a dipole source in the 2-D conductive structures. Computing costs are considerably minimized by reducing the full three-dimensional problem to a series of two-dimensional problems. This is accomplished by transforming the problem into y-wave number (Ky) domain using Fourier transform and the y-axis is parallel to the structural strike. In the Ky domain, two coupled partial differential equations for magnetic field Hy and electric field Ey are derived. For a specific value of Ky, the coupled equations are solved by the finite element method with isoparametric elements in the x-z plane. Application of the inverse Fourier transform to the Ky, domain provides the electric and magnetic fields in real space. The equations derived can be applied to general complex two-dimensional structures containing either electric or magnetic dipole source in any direction. In the modeling of the electromagnetic measurement, we adopted a pseudo-delta function to distribute the dipole source current and circumvent the problem of singularity at the source point. Moreover, the suggested method used isoparametric finite elements to accommodate the complex subsurface formation. For the large scale linear system derived from the discretization of the Maxwell's equations, several iterative solvers were used and compared to select the optimal one. A quantitative test of accuracy was presented which compared the finite element results with analytic solutions for a dipole source in homogeneous space for different ranges and different wave numbers Ky. to validate the addressed the effects of the distribution range τ of the homogeneous medium. code and check its effectiveness. In addition, we pseudo-delta function on the numerical results in 展开更多
关键词 2.5-d electromagnetic modeling frequency domain isoparametric finite element pseudo-delta function
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Modeling of dynamic recrystallization volume fraction evolution for AlCu4SiMg alloy and its application in FEM 被引量:11
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作者 Guo-zheng QUAN Rui-ju SHI +3 位作者 Jiang ZHAO Qiao LIU Wei XIONG Hui-min QIU 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2019年第6期1138-1151,共14页
To improve the understanding of coupling effect between dynamic recrystallization(DRX)behaviors and flow behaviors of as-cast AlCu4 SiMg, a finite element(FE) simulation equipped with the models of DRX evolution was i... To improve the understanding of coupling effect between dynamic recrystallization(DRX)behaviors and flow behaviors of as-cast AlCu4 SiMg, a finite element(FE) simulation equipped with the models of DRX evolution was implemented. A series of isothermal compression tests were performed primarily on a Gleeble-3500 thermo-mechanical simulator in a temperature range of 648-748 K and a strain rate range of 0.01-10 s-1.According to the measured true stress-strain data,the strain hardening rate curves(dσ/dε versus σ) were plotted to identify the critical strains for DRX initiation(εc). By further derivation of the related material constants, the DRX volume fraction equation and the strain for 50% DRX(ε0.5) equation were solved. Accordingly, the aforementioned DRX equations were implanted into the FE model to conduct a series of simulations for the isothermal compression tests. The results show that during the evolution of DRX volume fraction at a fixed strain rate, the strain required for the same amount of DRX volume fraction increases with decreasing temperature. In contrast, at a fixed temperature, it increases with increasing strain rate. Ultimately, the DRX kinetics model of AlCu4 SiMg alloy and the consequence of the FE analysis were validated by microstructure observations. 展开更多
关键词 AlCu4SiMg alloy DRX kinetics model DRX volume fraction flow behavior
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An executable modeling and analyzing approach to C4ISR architecture 被引量:4
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作者 HE Hongyue ZHU Weixing +1 位作者 LI Ruiyang DENG Qiaoyu 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2020年第1期109-117,共9页
To analyze the behavioral model of the command,control,communication,computer,intelligence,surveillance,reconnaissance(C4ISR)architecture,we propose an executable modeling and analyzing approach to it.First,the meta c... To analyze the behavioral model of the command,control,communication,computer,intelligence,surveillance,reconnaissance(C4ISR)architecture,we propose an executable modeling and analyzing approach to it.First,the meta concept model of the C4ISR architecture is introduced.According to the meta concept model,we construct the executable meta models of the C4ISR architecture by extending the meta models of fUML.Then,we define the concrete syntax and executable activity algebra(EAA)semantics for executable models.The semantics functions are introduced to translating the syntax description of executable models into the item of EAA.To support the execution of models,we propose the executable rules which are the structural operational semantics of EAA.Finally,an area air defense of the C4ISR system is used to illustrate the feasibility of the approach. 展开更多
关键词 COMMAND control communication computer INTELLIGENCE SURVEILLANCE reconnaissance(C4ISR)architecture meta model executable model algebraic semantics
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Constitutive Modeling for Ti-6Al-4V Alloy Machining Based on the SHPB Tests and Simulation 被引量:6
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作者 CHEN Guang KE Zhihong +1 位作者 REN Chengzu LI Jun 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2016年第5期962-970,共9页
A constitutive model is critical for the prediction accuracy of a metal cutting simulation. The highest strain rate involved in the cutting process can be in the range of 104-106 s 1. Flow stresses at high strain rate... A constitutive model is critical for the prediction accuracy of a metal cutting simulation. The highest strain rate involved in the cutting process can be in the range of 104-106 s 1. Flow stresses at high strain rates are close to that of cutting are difficult to test via experiments. Split Hopkinson compression bar (SHPB) technology is used to study the deformation behavior of Ti-6Al-4V alloy at strain rates of 10 -4-10 4s- 1. The Johnson Cook (JC) model was applied to characterize the flow stresses of the SHPB tests at various conditions. The parameters of the JC model are optimized by using a genetic algorithm technology. The JC plastic model and the energy density-based ductile failure criteria are adopted in the proposed SHPB finite element simulation model. The simulated flow stresses and the failure characteristics, such as the cracks along the adiabatic shear bands agree well with the experimental results. Afterwards, the SHPB simulation is used to simulate higher strain rate(approximately 3 × 10 4 s -1) conditions by minimizing the size of the specimen. The JC model parameters covering higher strain rate conditions which are close to the deformation condition in cutting were calculated based on the flow stresses obtained by using the SHPB tests (10 -4 - 10 4 s- 1) and simulation (up to 3 × 10 4 s - 1). The cutting simulation using the constitutive parameters is validated by the measured forces and chip morphology. The constitutive model and parameters for high strain rate conditions that are identical to those of cutting were obtained based on the SHPB tests and simulation. 展开更多
关键词 constitutive model Ti-6Al-4V alloy SHPB test high strain rate MACHINING
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Domain-specific modeling and verification for C4ISR capability requirements 被引量:4
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作者 董庆超 王智学 +2 位作者 陈国友 蒋鑫 张婷婷 《Journal of Central South University》 SCIE EI CAS 2012年第5期1334-1340,共7页
An approach was proposed to specify the C4ISR capability of domain-specific modeling language.To confine the domain modeling within a standard architecture framework,formally a C4ISR capability meta-ontology was defin... An approach was proposed to specify the C4ISR capability of domain-specific modeling language.To confine the domain modeling within a standard architecture framework,formally a C4ISR capability meta-ontology was defined according to the meta-model of DoD Architecture Framework.The meta-ontology is used for extending UML Profile so that the domain experts can model the C4ISR domains using the C4ISR capability meta-concepts to define a domain-specific modeling language.The domain models can be then checked to guarantee the consistency and completeness through converting the UML models into the Description Logic ontology and making use of inference engine Pellet to verify the ontology. 展开更多
关键词 C4ISR capability meta-ontology domain-specific modeling description logic
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Aquaporin-4-IgG-seropositive neuromyelitis optica spectrum disorders:progress of experimental models based on disease pathogenesis
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作者 Li Xu Huiming Xu Changyong Tang 《Neural Regeneration Research》 SCIE CAS 2025年第2期354-365,共12页
Neuromyelitis optica spectrum disorders are neuroinflammatory demyelinating disorders that lead to permanent visual loss and motor dysfunction.To date,no effective treatment exists as the exact causative mechanism rem... Neuromyelitis optica spectrum disorders are neuroinflammatory demyelinating disorders that lead to permanent visual loss and motor dysfunction.To date,no effective treatment exists as the exact causative mechanism remains unknown.Therefore,experimental models of neuromyelitis optica spectrum disorders are essential for exploring its pathogenesis and in screening for therapeutic targets.Since most patients with neuromyelitis optica spectrum disorders are seropositive for IgG autoantibodies against aquaporin-4,which is highly expressed on the membrane of astrocyte endfeet,most current experimental models are based on aquaporin-4-IgG that initially targets astrocytes.These experimental models have successfully simulated many pathological features of neuromyelitis optica spectrum disorders,such as aquaporin-4 loss,astrocytopathy,granulocyte and macrophage infiltration,complement activation,demyelination,and neuronal loss;however,they do not fully capture the pathological process of human neuromyelitis optica spectrum disorders.In this review,we summarize the currently known pathogenic mechanisms and the development of associated experimental models in vitro,ex vivo,and in vivo for neuromyelitis optica spectrum disorders,suggest potential pathogenic mechanisms for further investigation,and provide guidance on experimental model choices.In addition,this review summarizes the latest information on pathologies and therapies for neuromyelitis optica spectrum disorders based on experimental models of aquaporin-4-IgG-seropositive neuromyelitis optica spectrum disorders,offering further therapeutic targets and a theoretical basis for clinical trials. 展开更多
关键词 AQUAPORIN-4 experimental model neuromyelitis optica spectrum disorder PATHOGENESIS
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2.5-D DC Resistivity Modeling Considering Flexibility and Accuracy 被引量:1
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作者 汤井田 王飞燕 +1 位作者 肖晓 张林成 《Journal of Earth Science》 SCIE CAS CSCD 2011年第1期124-130,共7页
We highlighted the flexibility of using unstructured mesh together with the local refinement by a resistivity model with complicated topography. The effect of topography is emphasized. Based on this, we calculated a s... We highlighted the flexibility of using unstructured mesh together with the local refinement by a resistivity model with complicated topography. The effect of topography is emphasized. Based on this, we calculated a specific class of layered models and found that the accuracy is not always satisfactory by utilizing the standard approach. As an improvement, we employed the layered earth as the reference model to calculate the wavenumbers. The comparison demonstrates that the accuracy is considerably improved by using this enhanced approach. 展开更多
关键词 2-d topography 2.5-d DC resistivity modeling layered earth.
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结合TG-TDLAS与ReaxFF MD的烟煤热解CH_(4)生成机理研究
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作者 王庚乾 王远洋 +7 位作者 李光跃 田亚莉 和小虎 邱选兵 李传亮 梁五洲 姚凯 张君瑞 《光学精密工程》 北大核心 2026年第6期861-873,共13页
为了从原子尺度揭示烟煤热解过程中甲烷(CH_(4))的生成机理,以弥补传统实验手段难以捕捉其反应前驱体与微观路径的不足,本研究采用了热重-可调谐半导体激光吸收光谱(TG-TDLAS)实验与反应分子动力学模拟(ReaxFF MD)相结合的方法。首先,通... 为了从原子尺度揭示烟煤热解过程中甲烷(CH_(4))的生成机理,以弥补传统实验手段难以捕捉其反应前驱体与微观路径的不足,本研究采用了热重-可调谐半导体激光吸收光谱(TG-TDLAS)实验与反应分子动力学模拟(ReaxFF MD)相结合的方法。首先,通过TG-TDLAS实验获取了CH_(4)生成的宏观温度依赖性与动力学行为。其次,基于对烟煤样品的元素分析、红外光谱和^(13)C核磁共振表征,构建了烟煤分子模型(C_(309)H_(203)N_(3)O_(18)),并利用ReaxFF MD模拟分析了不同温度下CH_(3)自由基的断裂、氢迁移及CH_(4)生成的动态反应过程。结果表明,实验测得CH_(4)生成主要集中于450~750℃,峰值约600℃;模拟则揭示了CH_(4)生成的微观机理,即侧链CH_(3)在约1100 K断裂生成自由基,随后通过夺取邻近氢原子转化为CH_(4),并在2500 K达到峰值,两者在生成趋势上高度一致。结论认为,该方法从宏微观层面系统阐明了CH_(4)的生成源于前驱体断裂与氢夺取的平衡过程,验证了ReaxFF MD在揭示煤热解复杂反应网络中中间体行为的独特优势,为理解煤自燃、裂解路径及提高能源转化效率提供了理论依据。 展开更多
关键词 ReaxFF MD 热解 煤分子模型 CH_(4)
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Constitutive modeling of compression behavior of TC4 tube based on modified Arrhenius and artificial neural network models 被引量:5
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作者 Zhi-Jun Tao He Yang +2 位作者 Heng Li Jun Ma Peng-Fei Gao 《Rare Metals》 SCIE EI CAS CSCD 2016年第2期162-171,共10页
Warm rotary draw bending provides a feasible method to form the large-diameter thin-walled(LDTW)TC4 bent tubes, which are widely used in the pneumatic system of aircrafts. An accurate prediction of flow behavior of ... Warm rotary draw bending provides a feasible method to form the large-diameter thin-walled(LDTW)TC4 bent tubes, which are widely used in the pneumatic system of aircrafts. An accurate prediction of flow behavior of TC4 tubes considering the couple effects of temperature,strain rate and strain is critical for understanding the deformation behavior of metals and optimizing the processing parameters in warm rotary draw bending of TC4 tubes. In this study, isothermal compression tests of TC4 tube alloy were performed from 573 to 873 K with an interval of 100 K and strain rates of 0.001, 0.010 and0.100 s^(-1). The prediction of flow behavior was done using two constitutive models, namely modified Arrhenius model and artificial neural network(ANN) model. The predictions of these constitutive models were compared using statistical measures like correlation coefficient(R), average absolute relative error(AARE) and its variation with the deformation parameters(temperature, strain rate and strain). Analysis of statistical measures reveals that the two models show high predicted accuracy in terms of R and AARE. Comparatively speaking, the ANN model presents higher predicted accuracy than the modified Arrhenius model. In addition, the predicted accuracy of ANN model presents high stability at the whole deformation parameter ranges, whereas the predictability of the modified Arrhenius model has some fluctuation at different deformation conditions. It presents higher predicted accuracy at temperatures of 573-773 K, strain rates of 0.010-0.100 s^(-1)and strain of 0.04-0.32, while low accuracy at temperature of 873 K, strain rates of 0.001 s^(-1)and strain of 0.36-0.48.Thus, the application of modified Arrhenius model is limited by its relatively low predicted accuracy at some deformation conditions, while the ANN model presents very high predicted accuracy at all deformation conditions,which can be used to study the compression behavior of TC4 tube at the temperature range of 573-873 K and the strain rate of 0.001-0.100 s^(-1). It can provide guideline for the design of processing parameters in warm rotary draw bending of LDTW TC4 tubes. 展开更多
关键词 TC4 tube Compression behavior Constitutive model Modified Arrhenius model Neural network model
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Solubility and mass transfer of H2, CH4, and their mixtures in vacuum gas oil: An experimental and modeling study 被引量:2
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作者 Zhigang Lei Yifan Jiang +4 位作者 Yao Liu Yichun Dong Gangqiang Yu Yanyong Sun Ruili Guo 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2019年第12期3000-3009,共10页
In this work,the solubility data and liquid-phase mass transfer coefficients of hydrogen(H2),methane(CH4)and their mixtures in vacuum gas oil(VGO)at temperatures(353.15-453.15 K)and pressures(1-7 MPa)were measured,whi... In this work,the solubility data and liquid-phase mass transfer coefficients of hydrogen(H2),methane(CH4)and their mixtures in vacuum gas oil(VGO)at temperatures(353.15-453.15 K)and pressures(1-7 MPa)were measured,which are necessary for catalytic cracking process simulation and design.The solubility of H2 and CH4 in VGO increases with the increase of pressure,but decreases with the increase of temperature.Henry’s constants of H2 and CH4 follow the relation of In H=-413.05/T+5.27 and In H=-990.67/T+5.87,respectively.The molar fractions of H2 and system pressures at different equilibrium time were measured to estimate the liquid-phase mass transfer coefficients.The results showed that with the increase of pressure,the liquid-phase mass transfer coefficients increase.Furthermore,the solubility of H2 and CH4 in VGO was predicted by the predictive COSMO-RS model,and the predicted values agree well with experimental data.In addition,the gas-liquid equilibrium(GLE)for H2+CH4+VGO system at different feeding gas ratios in volume fraction(i.e.,H285%+CH415%and H290%+CH410%)was measured.The selectivity of H2 to CH4 predicted by the COSMO-RS model agrees well with experimental data.This work provides the basic thermodynamic and dynamic data for fuel oil catalytic cracking processes. 展开更多
关键词 H2 CH4 VACUUM gas oil(VGO) SOLUBILITY Mass transfer COSMO-RS model
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