In order to realize the simple and rapid detection of antibiotic contaminants in environmental water,the para-sulfocalix[4]arene(pSC_(4))functionalized gold nanoparticles(Au NPs)composites(pSC_(4)-Au NPs)were prepared...In order to realize the simple and rapid detection of antibiotic contaminants in environmental water,the para-sulfocalix[4]arene(pSC_(4))functionalized gold nanoparticles(Au NPs)composites(pSC_(4)-Au NPs)were prepared by sodium borohydride reduction.Here,a rapid and sensitive electrochemical sensor for the detection of antibiotic contaminants in water was constructed.The detection mechanism and the signaling changes of the different sulfamethazine(SMZ)concentrations were further explored based on pSC_(4)-Au NPs/SMZ modified glassy carbon electrode through aggregation of gold nanoparticles induced by host-vip recognition of SMZ and pSC_(4).The results suggested that this method achieved rapid and ultrasensitive detection of SMZ with a limit of detection of 0.0038 ng/m L(linear detection range of 1.0-1.0×10^(4)ng/m L).The recoveries ranged from 91.1%to 97.0%with relative standard deviations(RSDs)of1.5%-3.5%.The accurate detection of SMZ in recovery rate of spiking assay proved the potential practical application of the sensor.Host-vip recognition induced Au NPs aggregation results in dramatic signal enhancement for electrochemical impedimetric detection assay of SMZ.This detection method provides a new concept for developing sensitive electrochemical sensors for simple and sensitive detection of small molecules in water.展开更多
基金financially supported by National Natural Science Foundation of China(No.42301095)。
文摘In order to realize the simple and rapid detection of antibiotic contaminants in environmental water,the para-sulfocalix[4]arene(pSC_(4))functionalized gold nanoparticles(Au NPs)composites(pSC_(4)-Au NPs)were prepared by sodium borohydride reduction.Here,a rapid and sensitive electrochemical sensor for the detection of antibiotic contaminants in water was constructed.The detection mechanism and the signaling changes of the different sulfamethazine(SMZ)concentrations were further explored based on pSC_(4)-Au NPs/SMZ modified glassy carbon electrode through aggregation of gold nanoparticles induced by host-vip recognition of SMZ and pSC_(4).The results suggested that this method achieved rapid and ultrasensitive detection of SMZ with a limit of detection of 0.0038 ng/m L(linear detection range of 1.0-1.0×10^(4)ng/m L).The recoveries ranged from 91.1%to 97.0%with relative standard deviations(RSDs)of1.5%-3.5%.The accurate detection of SMZ in recovery rate of spiking assay proved the potential practical application of the sensor.Host-vip recognition induced Au NPs aggregation results in dramatic signal enhancement for electrochemical impedimetric detection assay of SMZ.This detection method provides a new concept for developing sensitive electrochemical sensors for simple and sensitive detection of small molecules in water.
