[目的]明确36%烯肟·氟环唑SC对玉米小斑病的防治效果。[方法]以17%唑醚·氟环唑SC和30%肟菌·戊唑醇SC为对照药剂,在山东省潍坊市寒亭区高里街道河南村玉米田进行田间小区试验。[结果]36%烯肟·氟环唑SC81、108 g a.i....[目的]明确36%烯肟·氟环唑SC对玉米小斑病的防治效果。[方法]以17%唑醚·氟环唑SC和30%肟菌·戊唑醇SC为对照药剂,在山东省潍坊市寒亭区高里街道河南村玉米田进行田间小区试验。[结果]36%烯肟·氟环唑SC81、108 g a.i./hm^(2)处理对玉米小斑病效果优于对照药剂17%唑醚·氟环唑SC和30%肟菌·戊唑醇SC,54 g a.i./hm^(2)的36%烯肟·氟环唑SC处理对玉米小斑病效果与对照药剂无显著性差异。[结论]使用36%烯肟·氟环唑SC54~108 g a.i./hm^(2)在玉米小斑病发病前或发病初期茎叶均匀喷雾,间隔7~10 d再施用1次,可有效防治玉米小斑病。展开更多
BACKGROUND Liver cirrhosis(LC)affect millions of people worldwide.The pathogenesis of cirrhosis involves complex interactions between immune responses and gut microbiota.Recent studies have highlighted the role of the...BACKGROUND Liver cirrhosis(LC)affect millions of people worldwide.The pathogenesis of cirrhosis involves complex interactions between immune responses and gut microbiota.Recent studies have highlighted the role of the interleukin-36(IL-36)subfamily in inflammation and immune regulation.However,the relationship between serum IL-36 subfamily levels and gut microbiota in cirrhosis patients remains unclear.This study aimed to explore the clinical significance of serum IL-36 subfamily levels and their association with gut microbiota in cirrhosis patients.AIM To explore the clinical significance of serum IL-36 subfamily levels and their relationship with gut microbiota among cirrhosis patients.METHODS Sixty-one cirrhosis patients were enrolled from Lihuili Hospital of Ningbo University from May 2022 to November 2023 as the LC group and 29 healthy volunteers as the healthy control(HC)group.The serum expressions of IL-36α,IL-36β, IL-36γ, IL-36Ra, and IL-38 were measured through ELISA, while 16S rRNA gene sequencing was employed torate microbial community in human fecal samples.RESULTSThe serum levels of IL-36α, IL-36γ, IL-36Ra, and IL-38 in the LC group remarkably exceeded those in the HC group(P < 0.05). IL-36α, IL-36γ, and IL-38 were related positively to the Child-Pugh score (P < 0.05) and prominentlyexceeded those in the Child-Pugh C group (P < 0.05). The absolute abundance of harmful bacteria (Bacteroides,Bifidobacterium, Faecalibacterium) remarkably rose, while the beneficial bacteria (Firmicutes, Bacteroides, Escherichia-Shigella) notably decreased in the LC group (P < 0.05). IL-36α, IL-36γ, and IL-38 related positively to Lactobacillus(P < 0.05), while IL-38 negatively related to Fusicatenibacter (P < 0.05).CONCLUSIONIL-36γ and IL-38 show promise as potential biomarkers for LC progression, but further validation is required.展开更多
文摘[目的]明确36%烯肟·氟环唑SC对玉米小斑病的防治效果。[方法]以17%唑醚·氟环唑SC和30%肟菌·戊唑醇SC为对照药剂,在山东省潍坊市寒亭区高里街道河南村玉米田进行田间小区试验。[结果]36%烯肟·氟环唑SC81、108 g a.i./hm^(2)处理对玉米小斑病效果优于对照药剂17%唑醚·氟环唑SC和30%肟菌·戊唑醇SC,54 g a.i./hm^(2)的36%烯肟·氟环唑SC处理对玉米小斑病效果与对照药剂无显著性差异。[结论]使用36%烯肟·氟环唑SC54~108 g a.i./hm^(2)在玉米小斑病发病前或发病初期茎叶均匀喷雾,间隔7~10 d再施用1次,可有效防治玉米小斑病。
基金Supported by Key Project of the Ningbo Natural Science Foundation,Zhejiang Province,China,No.2022J253Key Technology R&D Project of Ningbo City,No.2023Z208+1 种基金Traditional Chinese Medicine project,Zhejiang Province,No.2024ZF028the Key Project of Health Science and Technology Foundation,Zhejiang Province,China,No.WKJ-ZJ-2551.
文摘BACKGROUND Liver cirrhosis(LC)affect millions of people worldwide.The pathogenesis of cirrhosis involves complex interactions between immune responses and gut microbiota.Recent studies have highlighted the role of the interleukin-36(IL-36)subfamily in inflammation and immune regulation.However,the relationship between serum IL-36 subfamily levels and gut microbiota in cirrhosis patients remains unclear.This study aimed to explore the clinical significance of serum IL-36 subfamily levels and their association with gut microbiota in cirrhosis patients.AIM To explore the clinical significance of serum IL-36 subfamily levels and their relationship with gut microbiota among cirrhosis patients.METHODS Sixty-one cirrhosis patients were enrolled from Lihuili Hospital of Ningbo University from May 2022 to November 2023 as the LC group and 29 healthy volunteers as the healthy control(HC)group.The serum expressions of IL-36α,IL-36β, IL-36γ, IL-36Ra, and IL-38 were measured through ELISA, while 16S rRNA gene sequencing was employed torate microbial community in human fecal samples.RESULTSThe serum levels of IL-36α, IL-36γ, IL-36Ra, and IL-38 in the LC group remarkably exceeded those in the HC group(P < 0.05). IL-36α, IL-36γ, and IL-38 were related positively to the Child-Pugh score (P < 0.05) and prominentlyexceeded those in the Child-Pugh C group (P < 0.05). The absolute abundance of harmful bacteria (Bacteroides,Bifidobacterium, Faecalibacterium) remarkably rose, while the beneficial bacteria (Firmicutes, Bacteroides, Escherichia-Shigella) notably decreased in the LC group (P < 0.05). IL-36α, IL-36γ, and IL-38 related positively to Lactobacillus(P < 0.05), while IL-38 negatively related to Fusicatenibacter (P < 0.05).CONCLUSIONIL-36γ and IL-38 show promise as potential biomarkers for LC progression, but further validation is required.
