The polymer-ceramic composite electrolyte is considered as one of promising electrolytes for solid-state battery.However,in previous research,ceramic particles are usually dispersed in polymer matrix and could not for...The polymer-ceramic composite electrolyte is considered as one of promising electrolytes for solid-state battery.However,in previous research,ceramic particles are usually dispersed in polymer matrix and could not form continuous Li+conductive channels.The agglomeration of ceramic particles could also lead to low ionic conductivity and poor interfacial electrode/electrolyte contact.In this paper,self-supported porous Li_(6.4)La_(3) Zr_(1.4)Ta_(0.6)O_(12)(LLZTO) electrolyte is synthesized by gelcasting process,which possesses three-dimensional(3D) interconnected pore channels and relatively high strength.The 1,3-dioxolane(DOL) could penetrate into the porous LLZTO framework for its excellent fluidity.The subsequent in situ polymerization process by thermal treatment could completely fill the internal pores and improve the interfacial contact with electrode.The resulting 3D composite electrolyte with dual continuous Li+transport channels in ceramic and polymer components exhibits high ionic conductivity of 2.8 × 10^(-4) S·cm^(-1) at room temperature and low Li/electrolyte interfacial resistance of 94 Ω·cm^(2) at 40 ℃.The corresponding Li/Li symmetric cell delivers stable voltage profiles for over 600 h under 0.1 and 0.2 mA·cm^(-2).The solid-state Li/LiFePO_(4) battery shows superior rate and cycling performance under 0.1 C and 0.2 C.This work guides the preparation of composite electrolyte with dual continuous Li+conductive paths as well as high ceramic ratio and interface modification strategy for solid-state Li metal battery.展开更多
1,3-dioxolane （DOL） was originally used to pretreat a lithium metal electrode to improve its interfacial characteristics. Electrochemical impedance spectra （EIS） meastLrements revealed that, after the DOL pretreat...1,3-dioxolane （DOL） was originally used to pretreat a lithium metal electrode to improve its interfacial characteristics. Electrochemical impedance spectra （EIS） meastLrements revealed that, after the DOL pretreatment, the lithium electrode had better interfacial stability during immersion in electrolyte and as repeated charge/discharge cycles. It was proved by SEaM that the pretreated one has smoother morphology and less dendrite after repeated charge/discharge cycles. Consequentially, benefiting from the better interface characteristics of the lithium electrode, the rechargeable lithium cell with a DOL-pretreated lithium anode had the obviously enhanced discharging performance and better cyclability.展开更多
Nine title compounds were synthesized. Their strucures were identified by means of IR, EA, 1H NMR and MS. The results from the primary biological test show that all the compounds have some activitiies of fungicide and...Nine title compounds were synthesized. Their strucures were identified by means of IR, EA, 1H NMR and MS. The results from the primary biological test show that all the compounds have some activitiies of fungicide and plant growth regulator. When R group is 2,4 Cl 2C 6H 3, compound 2 or compound 4 shows better biological activities.展开更多
1,3-dioxolane (DOL) is originally used to pretreat the lithium metal electrode in order to passivate lithium metal and improve its interface stability. Through electrochemical impedance spectra (EIS) and cathodic pola...1,3-dioxolane (DOL) is originally used to pretreat the lithium metal electrode in order to passivate lithium metal and improve its interface stability. Through electrochemical impedance spectra (EIS) and cathodic polarization measurements of pretreated and untreated electrodes, it was found that 1,3-dioxolane could form a stable passivating film on the surface of lithium electrode. And such film could enhance effectively the interfacial stability of lithium electrode, without depressing its kinetics characteristic. Consequentially, further tests of the cell-performance during repeated charge/discharge cycles showed that the cell with DOL pretreated anode had better discharging performance and longer cycle life because of the passivating and protective effects of 1,3-dioxolane pretreatment on lithium electrode.展开更多
1,3-dioxolane (DOL) was originally used to pretreat a lithium metal electrode to improve its interfacial characteristics. Electrochemical impedance spectra (EIS) measurements revealed that,after the DOL pretreatment,t...1,3-dioxolane (DOL) was originally used to pretreat a lithium metal electrode to improve its interfacial characteristics. Electrochemical impedance spectra (EIS) measurements revealed that,after the DOL pretreatment,the lithium electrode had better interfacial stability during immersion in electrolyte and as repeated charge/discharge cycles. It was proved by SEM that the pretreated one has smoother morphology and less dendrite after repeated charge/discharge cycles. Consequentially,benefiting from the better interface characteristics of the lithium electrode,the rechargeable lithium cell with a DOL-pretreated lithium anode had the obviously enhanced discharging performance and better cyclability.展开更多
Novel 1,3-dioxolane C-nucleoside analogues of tiazofurin 2-(2-hydroxymethyl-1,3-dioxolan-4-yl)-1,3-thiazole- 4-carboxamide as well as N-nucleoside analogues of substituted imidazoles 1-(2-hydroxymethyl-1,3-dioxolan- 4...Novel 1,3-dioxolane C-nucleoside analogues of tiazofurin 2-(2-hydroxymethyl-1,3-dioxolan-4-yl)-1,3-thiazole- 4-carboxamide as well as N-nucleoside analogues of substituted imidazoles 1-(2-hydroxymethyl-1,3-dioxolan- 4-yl)-4-nitroimidazole and 1-(2-hydroxymethyl-1,3-dioxolan-4-yl)-4,5-dicyanoimidazole were synthesized from methyl acrylate through a multistep procedure. Their structures were confirmed by IR, 1H NMR, 13C NMR spectra and elemental analysis.展开更多
溃疡性结肠炎(ulcerative colitis,UC)是一种以结肠黏膜及黏膜下层炎症为主要特征的慢性非特异性炎症,其致病机制复杂,易反复发作,现代医学研究认为其涉及氧化应激、免疫失衡等多方面因素。信号转导和转录激活因子3(signal transducer a...溃疡性结肠炎(ulcerative colitis,UC)是一种以结肠黏膜及黏膜下层炎症为主要特征的慢性非特异性炎症,其致病机制复杂,易反复发作,现代医学研究认为其涉及氧化应激、免疫失衡等多方面因素。信号转导和转录激活因子3(signal transducer and activator of transcription,STAT3)是调节细胞生长、分化和存活的重要因子,可被相关细胞因子激活,从而介导炎症、氧化应激及免疫反应以影响UC病理进程,并与核因子κB(nuclear factor kappa-B,NF-κB)、NOD样受体热蛋白结构域相关蛋白3(NOD-like receptor thermal protein domain associated protein 3,NLRP3)、细胞因子信号传导抑制因子(suppressor of cytokine signaling,SOCSs)等信号通路存在串扰现象。STAT3作为近年来UC相关研究的热点之一,本文综述了中药通过调控STAT3信号通路防治UC的研究进展,深入探究了STAT3激活及介导UC病理过程的分子机制,以及中药成分如何通过多途径调控STAT3信号通路,发挥其潜在的作用机制。相关研究揭示了中药通过调节STAT3信号通路,不仅有效抑制炎症、氧化应激的发生,还能在调控免疫反应、维持肠道屏障功能及完整性等方面发挥重要作用,有望为治疗UC提供新思路。展开更多
基金financially supported by the National Natural Science Foundation of China (Nos.52173257 and 51872159)。
文摘The polymer-ceramic composite electrolyte is considered as one of promising electrolytes for solid-state battery.However,in previous research,ceramic particles are usually dispersed in polymer matrix and could not form continuous Li+conductive channels.The agglomeration of ceramic particles could also lead to low ionic conductivity and poor interfacial electrode/electrolyte contact.In this paper,self-supported porous Li_(6.4)La_(3) Zr_(1.4)Ta_(0.6)O_(12)(LLZTO) electrolyte is synthesized by gelcasting process,which possesses three-dimensional(3D) interconnected pore channels and relatively high strength.The 1,3-dioxolane(DOL) could penetrate into the porous LLZTO framework for its excellent fluidity.The subsequent in situ polymerization process by thermal treatment could completely fill the internal pores and improve the interfacial contact with electrode.The resulting 3D composite electrolyte with dual continuous Li+transport channels in ceramic and polymer components exhibits high ionic conductivity of 2.8 × 10^(-4) S·cm^(-1) at room temperature and low Li/electrolyte interfacial resistance of 94 Ω·cm^(2) at 40 ℃.The corresponding Li/Li symmetric cell delivers stable voltage profiles for over 600 h under 0.1 and 0.2 mA·cm^(-2).The solid-state Li/LiFePO_(4) battery shows superior rate and cycling performance under 0.1 C and 0.2 C.This work guides the preparation of composite electrolyte with dual continuous Li+conductive paths as well as high ceramic ratio and interface modification strategy for solid-state Li metal battery.
基金This project was financially supported by the Foundation of Science-Technology Research Program of Guangdong Prov-ince, China (No. 2003C105006).
文摘1,3-dioxolane （DOL） was originally used to pretreat a lithium metal electrode to improve its interfacial characteristics. Electrochemical impedance spectra （EIS） meastLrements revealed that, after the DOL pretreatment, the lithium electrode had better interfacial stability during immersion in electrolyte and as repeated charge/discharge cycles. It was proved by SEaM that the pretreated one has smoother morphology and less dendrite after repeated charge/discharge cycles. Consequentially, benefiting from the better interface characteristics of the lithium electrode, the rechargeable lithium cell with a DOL-pretreated lithium anode had the obviously enhanced discharging performance and better cyclability.
基金Supported by the Natural Science Foudation of Shandong Province(No.Q 99B16 ) and the National Natural ScienceFoundation of China(No.2 0 0 75 0 13)
文摘Nine title compounds were synthesized. Their strucures were identified by means of IR, EA, 1H NMR and MS. The results from the primary biological test show that all the compounds have some activitiies of fungicide and plant growth regulator. When R group is 2,4 Cl 2C 6H 3, compound 2 or compound 4 shows better biological activities.
文摘1,3-dioxolane (DOL) is originally used to pretreat the lithium metal electrode in order to passivate lithium metal and improve its interface stability. Through electrochemical impedance spectra (EIS) and cathodic polarization measurements of pretreated and untreated electrodes, it was found that 1,3-dioxolane could form a stable passivating film on the surface of lithium electrode. And such film could enhance effectively the interfacial stability of lithium electrode, without depressing its kinetics characteristic. Consequentially, further tests of the cell-performance during repeated charge/discharge cycles showed that the cell with DOL pretreated anode had better discharging performance and longer cycle life because of the passivating and protective effects of 1,3-dioxolane pretreatment on lithium electrode.
文摘1,3-dioxolane (DOL) was originally used to pretreat a lithium metal electrode to improve its interfacial characteristics. Electrochemical impedance spectra (EIS) measurements revealed that,after the DOL pretreatment,the lithium electrode had better interfacial stability during immersion in electrolyte and as repeated charge/discharge cycles. It was proved by SEM that the pretreated one has smoother morphology and less dendrite after repeated charge/discharge cycles. Consequentially,benefiting from the better interface characteristics of the lithium electrode,the rechargeable lithium cell with a DOL-pretreated lithium anode had the obviously enhanced discharging performance and better cyclability.
基金Project supported by the National Natural Science Foundation of China (No. 21172049).
文摘Novel 1,3-dioxolane C-nucleoside analogues of tiazofurin 2-(2-hydroxymethyl-1,3-dioxolan-4-yl)-1,3-thiazole- 4-carboxamide as well as N-nucleoside analogues of substituted imidazoles 1-(2-hydroxymethyl-1,3-dioxolan- 4-yl)-4-nitroimidazole and 1-(2-hydroxymethyl-1,3-dioxolan-4-yl)-4,5-dicyanoimidazole were synthesized from methyl acrylate through a multistep procedure. Their structures were confirmed by IR, 1H NMR, 13C NMR spectra and elemental analysis.
文摘溃疡性结肠炎(ulcerative colitis,UC)是一种以结肠黏膜及黏膜下层炎症为主要特征的慢性非特异性炎症,其致病机制复杂,易反复发作,现代医学研究认为其涉及氧化应激、免疫失衡等多方面因素。信号转导和转录激活因子3(signal transducer and activator of transcription,STAT3)是调节细胞生长、分化和存活的重要因子,可被相关细胞因子激活,从而介导炎症、氧化应激及免疫反应以影响UC病理进程,并与核因子κB(nuclear factor kappa-B,NF-κB)、NOD样受体热蛋白结构域相关蛋白3(NOD-like receptor thermal protein domain associated protein 3,NLRP3)、细胞因子信号传导抑制因子(suppressor of cytokine signaling,SOCSs)等信号通路存在串扰现象。STAT3作为近年来UC相关研究的热点之一,本文综述了中药通过调控STAT3信号通路防治UC的研究进展,深入探究了STAT3激活及介导UC病理过程的分子机制,以及中药成分如何通过多途径调控STAT3信号通路,发挥其潜在的作用机制。相关研究揭示了中药通过调节STAT3信号通路,不仅有效抑制炎症、氧化应激的发生,还能在调控免疫反应、维持肠道屏障功能及完整性等方面发挥重要作用,有望为治疗UC提供新思路。
