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SFC_DeepLabv3+:A Lightweight Grape Image Segmentation Method Based on Content-Guided Attention Fusion
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作者 Yuchao Xia Jing Qiu 《Computers, Materials & Continua》 2025年第8期2531-2547,共17页
In recent years,fungal diseases affecting grape crops have attracted significant attention.Currently,the assessment of black rot severitymainly depends on the ratio of lesion area to leaf surface area.However,effectiv... In recent years,fungal diseases affecting grape crops have attracted significant attention.Currently,the assessment of black rot severitymainly depends on the ratio of lesion area to leaf surface area.However,effectively and accurately segmenting leaf lesions presents considerable challenges.Existing grape leaf lesion segmentationmodels have several limitations,such as a large number of parameters,long training durations,and limited precision in extracting small lesions and boundary details.To address these issues,we propose an enhanced DeepLabv3+model incorporating Strip Pooling,Content-Guided Fusion,and Convolutional Block Attention Module(SFC_DeepLabv3+),an enhanced lesion segmentation method based on DeepLabv3+.This approach uses the lightweight MobileNetv2 backbone to replace the original Xception,incorporates a lightweight convolutional block attention module,and introduces a content-guided feature fusion module to improve the detection accuracy of small lesions and blurred boundaries.Experimental results showthat the enhancedmodel achieves a mean Intersection overUnion(mIoU)of 90.98%,amean Pixel Accuracy(mPA)of 94.33%,and a precision of 95.84%.This represents relative gains of 2.22%,1.78%,and 0.89%respectively compared to the original model.Additionally,its complexity is significantly reduced without sacrificing performance,the parameter count is reduced to 6.27 M,a decrease of 88.5%compared to the original model,floating point of operations(GFLOPs)drops from 83.62 to 29.00 G,a reduction of 65.1%.Additionally,Frames Per Second(FPS)increases from 63.7 to 74.3 FPS,marking an improvement of 16.7%.Compared to other models,the improved architecture shows faster convergence and superior segmentation accuracy,making it highly suitable for applications in resource-constrained environments. 展开更多
关键词 Grape leaf leaf segmentation LIGHTWEIGHT feature fusion DeepLabv3+
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Multi-Stage Hierarchical Feature Extraction for Efficient 3D Medical Image Segmentation
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作者 Jion Kim Jayeon Kim Byeong-Seok Shin 《Computers, Materials & Continua》 2025年第6期5429-5443,共15页
Research has been conducted to reduce resource consumption in 3D medical image segmentation for diverse resource-constrained environments.However,decreasing the number of parameters to enhance computational efficiency... Research has been conducted to reduce resource consumption in 3D medical image segmentation for diverse resource-constrained environments.However,decreasing the number of parameters to enhance computational efficiency can also lead to performance degradation.Moreover,these methods face challenges in balancing global and local features,increasing the risk of errors in multi-scale segmentation.This issue is particularly pronounced when segmenting small and complex structures within the human body.To address this problem,we propose a multi-stage hierarchical architecture composed of a detector and a segmentor.The detector extracts regions of interest(ROIs)in a 3D image,while the segmentor performs segmentation in the extracted ROI.Removing unnecessary areas in the detector allows the segmentation to be performed on a more compact input.The segmentor is designed with multiple stages,where each stage utilizes different input sizes.It implements a stage-skippingmechanism that deactivates certain stages using the initial input size.This approach minimizes unnecessary computations on segmenting the essential regions to reduce computational overhead.The proposed framework preserves segmentation performance while reducing resource consumption,enabling segmentation even in resource-constrained environments. 展开更多
关键词 Volumetric segmentation 3D medical images computational resources
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Advanced Brain Tumor Segmentation in Magnetic Resonance Imaging via 3D U-Net and Generalized Gaussian Mixture Model-Based Preprocessing
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作者 Khalil Ibrahim Lairedj Zouaoui Chama +5 位作者 Amina Bagdaoui Samia Larguech Younes Menni Nidhal Becheikh Lioua Kolsi Badr M.Alshammari 《Computer Modeling in Engineering & Sciences》 2025年第8期2419-2443,共25页
Brain tumor segmentation from Magnetic Resonance Imaging(MRI)supports neurologists and radiologists in analyzing tumors and developing personalized treatment plans,making it a crucial yet challenging task.Supervised m... Brain tumor segmentation from Magnetic Resonance Imaging(MRI)supports neurologists and radiologists in analyzing tumors and developing personalized treatment plans,making it a crucial yet challenging task.Supervised models such as 3D U-Net perform well in this domain,but their accuracy significantly improves with appropriate preprocessing.This paper demonstrates the effectiveness of preprocessing in brain tumor segmentation by applying a pre-segmentation step based on the Generalized Gaussian Mixture Model(GGMM)to T1 contrastenhanced MRI scans from the BraTS 2020 dataset.The Expectation-Maximization(EM)algorithm is employed to estimate parameters for four tissue classes,generating a new pre-segmented channel that enhances the training and performance of the 3DU-Net model.The proposed GGMM+3D U-Net framework achieved a Dice coefficient of 0.88 for whole tumor segmentation,outperforming both the standard multiscale 3D U-Net(0.84)and MMU-Net(0.85).It also delivered higher Intersection over Union(IoU)scores compared to models trained without preprocessing or with simpler GMM-based segmentation.These results,supported by qualitative visualizations,suggest that GGMM-based preprocessing should be integrated into brain tumor segmentation pipelines to optimize performance. 展开更多
关键词 Magnetic resonance imaging(MRI) imaging technology GGMM EM algorithm 3D U-Net segmentation
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Enhancing 3D U-Net with Residual and Squeeze-and-Excitation Attention Mechanisms for Improved Brain Tumor Segmentation in Multimodal MRI
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作者 Yao-Tien Chen Nisar Ahmad Khursheed Aurangzeb 《Computer Modeling in Engineering & Sciences》 2025年第7期1197-1224,共28页
Accurate and efficient brain tumor segmentation is essential for early diagnosis,treatment planning,and clinical decision-making.However,the complex structure of brain anatomy and the heterogeneous nature of tumors pr... Accurate and efficient brain tumor segmentation is essential for early diagnosis,treatment planning,and clinical decision-making.However,the complex structure of brain anatomy and the heterogeneous nature of tumors present significant challenges for precise anomaly detection.While U-Net-based architectures have demonstrated strong performance in medical image segmentation,there remains room for improvement in feature extraction and localization accuracy.In this study,we propose a novel hybrid model designed to enhance 3D brain tumor segmentation.The architecture incorporates a 3D ResNet encoder known for mitigating the vanishing gradient problem and a 3D U-Net decoder.Additionally,to enhance the model’s generalization ability,Squeeze and Excitation attention mechanism is integrated.We introduce Gabor filter banks into the encoder to further strengthen the model’s ability to extract robust and transformation-invariant features from the complex and irregular shapes typical in medical imaging.This approach,which is not well explored in current U-Net-based segmentation frameworks,provides a unique advantage by enhancing texture-aware feature representation.Specifically,Gabor filters help extract distinctive low-level texture features,reducing the effects of texture interference and facilitating faster convergence during the early stages of training.Our model achieved Dice scores of 0.881,0.846,and 0.819 for Whole Tumor(WT),Tumor Core(TC),and Enhancing Tumor(ET),respectively,on the BraTS 2020 dataset.Cross-validation on the BraTS 2021 dataset further confirmed the model’s robustness,yielding Dice score values of 0.887 for WT,0.856 for TC,and 0.824 for ET.The proposed model outperforms several state-of-the-art existing models,particularly in accurately identifying small and complex tumor regions.Extensive evaluations suggest integrating advanced preprocessing with an attention-augmented hybrid architecture offers significant potential for reliable and clinically valuable brain tumor segmentation. 展开更多
关键词 3D MRI artificial intelligence deep learning AI in healthcare attention mechanism U-Net medical image analysis brain tumor segmentation BraTS 2021 BraTS 2020
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3D Instance Segmentation Using Deep Learning on RGB-D Indoor Data 被引量:1
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作者 Siddiqui Muhammad Yasir Amin Muhammad Sadiq Hyunsik Ahn 《Computers, Materials & Continua》 SCIE EI 2022年第9期5777-5791,共15页
3D object recognition is a challenging task for intelligent and robot systems in industrial and home indoor environments.It is critical for such systems to recognize and segment the 3D object instances that they encou... 3D object recognition is a challenging task for intelligent and robot systems in industrial and home indoor environments.It is critical for such systems to recognize and segment the 3D object instances that they encounter on a frequent basis.The computer vision,graphics,and machine learning fields have all given it a lot of attention.Traditionally,3D segmentation was done with hand-crafted features and designed approaches that didn’t achieve acceptable performance and couldn’t be generalized to large-scale data.Deep learning approaches have lately become the preferred method for 3D segmentation challenges by their great success in 2D computer vision.However,the task of instance segmentation is currently less explored.In this paper,we propose a novel approach for efficient 3D instance segmentation using red green blue and depth(RGB-D)data based on deep learning.The 2D region based convolutional neural networks(Mask R-CNN)deep learning model with point based rending module is adapted to integrate with depth information to recognize and segment 3D instances of objects.In order to generate 3D point cloud coordinates(x,y,z),segmented 2D pixels(u,v)of recognized object regions in the RGB image are merged into(u,v)points of the depth image.Moreover,we conducted an experiment and analysis to compare our proposed method from various points of view and distances.The experimentation shows the proposed 3D object recognition and instance segmentation are sufficiently beneficial to support object handling in robotic and intelligent systems. 展开更多
关键词 Instance segmentation 3D object segmentation deep learning point cloud coordinates
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慢性肾衰竭透析患者血清SP-D、PTX-3水平对合并细菌性肺炎的诊断效能
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作者 邵珏 李金玉 +1 位作者 汪成军 张赟辉 《热带医学杂志》 2025年第4期506-510,共5页
目的探讨慢性肾衰竭(CRF)透析患者血清表面活性蛋白-D(SP-D)、正五聚蛋白3(PTX-3)水平对合并细菌性肺炎的诊断效能,为临床早期诊断和有效治疗提供新的思路和方法。方法选取2019年10月-2023年10月黄山市人民医院收治的102例慢性肾衰竭透... 目的探讨慢性肾衰竭(CRF)透析患者血清表面活性蛋白-D(SP-D)、正五聚蛋白3(PTX-3)水平对合并细菌性肺炎的诊断效能,为临床早期诊断和有效治疗提供新的思路和方法。方法选取2019年10月-2023年10月黄山市人民医院收治的102例慢性肾衰竭透析患者作为研究对象,根据是否合并细菌性肺炎分为合并细菌性肺炎组(n=43)和未合并细菌性肺炎组(n=59)。采用酶联免疫吸附法检测所有研究对象血清SP-D、PTX-3水平。采用受试者工作特征(ROC)曲线评估血清SP-D、PTX-3水平对CRF患者合并细菌性肺炎的诊断价值,采用多因素logistic回归分析探讨CRF患者合并细菌性肺炎的影响因素。结果合并细菌性肺炎组患者血清SP-D、PTX-3水平显著高于未合并细菌性肺炎组,差异均有统计学意义(t=23.473、22.563,P均<0.05)。血清SP-D、PTX-3诊断慢性肾衰竭透析患者合并细菌性肺炎的曲线下面积(AUC)分别为0.832(95%CI:0.787~0.879)、0.746(95%CI:0.701~0.796),两者联合(串联实验)诊断的AUC为0.902(95%CI:0.858~0.951)。合并细菌性肺炎组患者年龄≥60岁比例、住院时间、合并疾病(糖尿病)、透析时间≥1年比例均高于未合并细菌性肺炎组,差异均有统计学意义(P均<0.05)。二分类logistic逐步回归分析显示,年龄≥60岁(OR=1.791,95%CI:1.225~2.620)、合并糖尿病(OR=2.762,95%CI:1.324~5.760)、血清SP-D≥188.27 g/L(OR=4.651,95%CI:1.822~11.868)、血清PTX-3≥17.83 ng/mL(OR=3.554,95%CI:1.741~7.253)是慢性肾衰竭透析患者合并细菌性肺炎的危险因素(P均<0.05)。结论血清SP-D、PTX-3水平在慢性肾衰竭透析合并细菌性肺炎患者中呈高表达,可作为诊断慢性肾衰竭透析患者合并细菌性肺炎潜在的生物学指标,两者联合诊断的效能更高。 展开更多
关键词 慢性肾衰竭 透析 细菌性肺炎 表面活性蛋白-d 正五聚蛋白3
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甘露糖蛋白、半乳甘露聚糖和1-3-β-D葡聚糖联合检测对艾滋病合并马尔尼菲篮状菌病的诊断价值 被引量:1
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作者 李小凤 张海燕 +1 位作者 何静 罗明 《中国热带医学》 北大核心 2025年第5期547-551,593,共6页
目的探讨甘露糖蛋白(mannoprotein,Mp1p)、半乳甘露聚糖(galactomannan,GM)和1-3-β-D葡聚糖(1-3-β-D glucan,BDG)单独和联合检测对艾滋病合并马尔尼菲篮状菌病(Talaromycosis marneffei,TSM)的诊断价值。方法收集291例艾滋病合并马尔... 目的探讨甘露糖蛋白(mannoprotein,Mp1p)、半乳甘露聚糖(galactomannan,GM)和1-3-β-D葡聚糖(1-3-β-D glucan,BDG)单独和联合检测对艾滋病合并马尔尼菲篮状菌病(Talaromycosis marneffei,TSM)的诊断价值。方法收集291例艾滋病合并马尔尼菲篮状菌住院患者和300例健康体检者外周血标本,检测Mp1p、GM和BDG并分析单独和联合检测诊断TSM的价值,采用ROC曲线分析Mp1p、GM、BDG和联合检测的诊断效能。结果在单独检测中,Mp1p、GM和BDG检测灵敏度和特异度之间差异有统计学意义(P<0.05),相较于GM和BDG,Mp1p的诊断效能最好,灵敏度和特异度最优。在两两联合检测中,Mp1p与GM组合灵敏度优于GM与BDG组合,差异有统计学意义(P<0.05);Mp1p与GM组合、Mp1p与BDG组合特异度优于GM与BDG组合,差异有统计学意义(P<0.05),Mp1p与GM组合的诊断效能最好。三者联合检测灵敏度优于两两联合检测,差异有统计学意义(P<0.05),Mp1p与GM组合、Mp1p与BDG组合特异度优于三者联合检测,差异有统计学意义(P<0.05)。Mp1p、GM、BDG检测阳性率分别在CD4^(+)T细胞计数≤100个/μL和>100个/μL患者中差异无统计学意义(P>0.05)。结论Mp1p、GM、BDG检测是艾滋病合并TSM早期辅助性诊断指标,其中Mp1p诊断效能优于GM和BDG,联合检测可提高诊断效能。 展开更多
关键词 甘露糖蛋白 半乳甘露聚糖 1-3-d葡聚糖 马尔尼菲篮状菌病 艾滋病
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Fluid-based moderate collision avoidance for UAV formation in 3-D low-altitude environments 被引量:1
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作者 Menghua ZHANG Honglun WANG +5 位作者 Zhiyu LI Yanxiang WANG Xianglun ZHANG Qiang TANG Shichao MA Jianfa WU 《Chinese Journal of Aeronautics》 2025年第6期533-551,共19页
Aiming to address the Unmanned Aerial Vehicle(UAV) formation collision avoidance problem in Three-Dimensional(3-D) low-altitude environments where dense various obstacles exist, a fluid-based path planning framework n... Aiming to address the Unmanned Aerial Vehicle(UAV) formation collision avoidance problem in Three-Dimensional(3-D) low-altitude environments where dense various obstacles exist, a fluid-based path planning framework named the Formation Interfered Fluid Dynamical System(FIFDS) with Moderate Evasive Maneuver Strategy(MEMS) is proposed in this study.First, the UAV formation collision avoidance problem including quantifiable performance indexes is formulated. Second, inspired by the phenomenon of fluids continuously flowing while bypassing objects, the FIFDS for multiple UAVs is presented, which contains a Parallel Streamline Tracking(PST) method for formation keeping and the traditional IFDS for collision avoidance. Third, to rationally balance flight safety and collision avoidance cost, MEMS is proposed to generate moderate evasive maneuvers that match up with collision risks. Comprehensively containing the time and distance safety information, the 3-D dynamic collision regions are modeled for collision prediction. Then, the moderate evasive maneuver principle is refined, which provides criterions of the maneuver amplitude and direction. On this basis, an analytical parameter mapping mechanism is designed to online optimize IFDS parameters. Finally, the performance of the proposed method is validated by comparative simulation results and real flight experiments using fixed-wing UAVs. 展开更多
关键词 Unmanned aerial vehicle Formation collision avoidance:3-d low-altitude environments Interfered fluid dynamical system 3-d dynamic collision region
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Semantic segmentation method of road scene based on Deeplabv3+ and attention mechanism 被引量:7
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作者 BAI Yanqiong ZHENG Yufu TIAN Hong 《Journal of Measurement Science and Instrumentation》 CAS CSCD 2021年第4期412-422,共11页
In the study of automatic driving,understanding the road scene is a key to improve driving safety.The semantic segmentation method could divide the image into different areas associated with semantic categories in acc... In the study of automatic driving,understanding the road scene is a key to improve driving safety.The semantic segmentation method could divide the image into different areas associated with semantic categories in accordance with the pixel level,so as to help vehicles to perceive and obtain the surrounding road environment information,which would improve driving safety.Deeplabv3+is the current popular semantic segmentation model.There are phenomena that small targets are missed and similar objects are easily misjudged during its semantic segmentation tasks,which leads to rough segmentation boundary and reduces semantic accuracy.This study focuses on the issue,based on the Deeplabv3+network structure and combined with the attention mechanism,to increase the weight of the segmentation area,and then proposes an improved Deeplabv3+fusion attention mechanism for road scene semantic segmentation method.First,a group of parallel position attention module and channel attention module are introduced on the Deeplabv3+encoding end to capture more spatial context information and high-level semantic information.Then,an attention mechanism is introduced to restore the spatial detail information,and the data shall be normalized in order to accelerate the convergence speed of the model at the decoding end.The effects of model segmentation with different attention-introducing mechanisms are compared and tested on CamVid and Cityscapes datasets.The experimental results show that the mean Intersection over Unons of the improved model segmentation accuracies on the two datasets are boosted by 6.88%and 2.58%,respectively,which is better than using Deeplabv3+.This method does not significantly increase the amount of network calculation and complexity,and has a good balance of speed and accuracy. 展开更多
关键词 autonomous driving road scene semantic segmentation Deeplabv3+ attention mechanism
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Semantic Segmentation Using DeepLabv3+ Model for Fabric Defect Detection 被引量:4
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作者 ZHU Runhu XIN Binjie +1 位作者 DENG Na FAN Mingzhu 《Wuhan University Journal of Natural Sciences》 CAS CSCD 2022年第6期539-549,共11页
Currently, numerous automatic fabric defect detection algorithms have been proposed. Traditional machine vision algorithms that set separate parameters for different textures and defects rely on the manual design of c... Currently, numerous automatic fabric defect detection algorithms have been proposed. Traditional machine vision algorithms that set separate parameters for different textures and defects rely on the manual design of corresponding features to complete the detection. To overcome the limitations of traditional algorithms, deep learning-based correlative algorithms can extract more complex image features and perform better in image classification and object detection. A pixel-level defect segmentation methodology using DeepLabv3+, a classical semantic segmentation network, is proposed in this paper. Based on ResNet-18,ResNet-50 and Mobilenetv2, three DeepLabv3+ networks are constructed, which are trained and tested from data sets produced by capturing or publicizing images. The experimental results show that the performance of three DeepLabv3+ networks is close to one another on the four indicators proposed(Precision, Recall, F1-score and Accuracy), proving them to achieve defect detection and semantic segmentation, which provide new ideas and technical support for fabric defect detection. 展开更多
关键词 fabric defect detection semantic segmentation deep learning DeepLabv3+
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A novel technique of three-dimensional reconstruction segmentation and analysis for sliced images of biological tissues 被引量:3
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作者 李晶 赵海燕 +4 位作者 阮兴云 徐永清 孟伟正 李鲲鹏 张景强 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 SCIE CAS CSCD 2005年第12期1210-1212,共3页
A novel technique of three-dimensional (3D) reconstruction, segmentation, display and analysis of series slices of images including microscopic wide field optical sectioning by deconvolution method, cryo-electron micr... A novel technique of three-dimensional (3D) reconstruction, segmentation, display and analysis of series slices of images including microscopic wide field optical sectioning by deconvolution method, cryo-electron microscope slices by Fou-rier-Bessel synthesis and electron tomography (ET), and a series of computed tomography (CT) was developed to perform si-multaneous measurement on the structure and function of biomedical samples. The paper presents the 3D reconstruction seg-mentation display and analysis results of pollen spore, chaperonin, virus, head, cervical bone, tibia and carpus. At the same time, it also puts forward some potential applications of the new technique in the biomedical realm. 展开更多
关键词 Sliced images 3D reconstruction and analysis 3D segmentation CHAPERONIN VIRUS
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A Local Contrast Fusion Based 3D Otsu Algorithm for Multilevel Image Segmentation 被引量:14
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作者 Ashish Kumar Bhandari Arunangshu Ghosh Immadisetty Vinod Kumar 《IEEE/CAA Journal of Automatica Sinica》 EI CSCD 2020年第1期200-213,共14页
To overcome the shortcomings of 1 D and 2 D Otsu’s thresholding techniques, the 3 D Otsu method has been developed.Among all Otsu’s methods, 3 D Otsu technique provides the best threshold values for the multi-level ... To overcome the shortcomings of 1 D and 2 D Otsu’s thresholding techniques, the 3 D Otsu method has been developed.Among all Otsu’s methods, 3 D Otsu technique provides the best threshold values for the multi-level thresholding processes. In this paper, to improve the quality of segmented images, a simple and effective multilevel thresholding method is introduced. The proposed approach focuses on preserving edge detail by computing the 3 D Otsu along the fusion phenomena. The advantages of the presented scheme include higher quality outcomes, better preservation of tiny details and boundaries and reduced execution time with rising threshold levels. The fusion approach depends upon the differences between pixel intensity values within a small local space of an image;it aims to improve localized information after the thresholding process. The fusion of images based on local contrast can improve image segmentation performance by minimizing the loss of local contrast, loss of details and gray-level distributions. Results show that the proposed method yields more promising segmentation results when compared to conventional1 D Otsu, 2 D Otsu and 3 D Otsu methods, as evident from the objective and subjective evaluations. 展开更多
关键词 1D Otsu 2D Otsu 3D Otsu image fusion local contrast multi-level image segmentation
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3D modeling of geological anomalies based on segmentation of multiattribute fusion 被引量:2
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作者 Liu Zhi-Ning Song Cheng-Yun +3 位作者 Li Zhi-Yong Cai Han-Peng Yao Xing-Miao Hu Guang-Min 《Applied Geophysics》 SCIE CSCD 2016年第3期519-528,581,共11页
3D modeling of geological bodies based on 3D seismic data is used to define the shape and volume of the bodies, which then can be directly applied to reservoir prediction, reserve estimation, and exploration. However,... 3D modeling of geological bodies based on 3D seismic data is used to define the shape and volume of the bodies, which then can be directly applied to reservoir prediction, reserve estimation, and exploration. However, multiattributes are not effectively used in 3D modeling. To solve this problem, we propose a novel method for building of 3D model of geological anomalies based on the segmentation of multiattribute fusion. First, we divide the seismic attributes into edge- and region-based seismic attributes. Then, the segmentation model incorporating the edge- and region-based models is constructed within the levelset- based framework. Finally, the marching cubes algorithm is adopted to extract the zero level set based on the segmentation results and build the 3D model of the geological anomaly. Combining the edge-and region-based attributes to build the segmentation model, we satisfy the independence requirement and avoid the problem of insufficient data of single seismic attribute in capturing the boundaries of geological anomalies. We apply the proposed method to seismic data from the Sichuan Basin in southwestern China and obtain 3D models of caves and channels. Compared with 3D models obtained based on single seismic attributes, the results are better agreement with reality. 展开更多
关键词 Geological anomaly multiattributes FUSION segmentation 3D modeling
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Segmentation of retinal fluid based on deep learning:application of three-dimensional fully convolutional neural networks in optical coherence tomography images 被引量:4
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作者 Meng-Xiao Li Su-Qin Yu +4 位作者 Wei Zhang Hao Zhou Xun Xu Tian-Wei Qian Yong-Jing Wan 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2019年第6期1012-1020,共9页
AIM: To explore a segmentation algorithm based on deep learning to achieve accurate diagnosis and treatment of patients with retinal fluid.METHODS: A two-dimensional(2D) fully convolutional network for retinal segment... AIM: To explore a segmentation algorithm based on deep learning to achieve accurate diagnosis and treatment of patients with retinal fluid.METHODS: A two-dimensional(2D) fully convolutional network for retinal segmentation was employed. In order to solve the category imbalance in retinal optical coherence tomography(OCT) images, the network parameters and loss function based on the 2D fully convolutional network were modified. For this network, the correlations of corresponding positions among adjacent images in space are ignored. Thus, we proposed a three-dimensional(3D) fully convolutional network for segmentation in the retinal OCT images.RESULTS: The algorithm was evaluated according to segmentation accuracy, Kappa coefficient, and F1 score. For the 3D fully convolutional network proposed in this paper, the overall segmentation accuracy rate is 99.56%, Kappa coefficient is 98.47%, and F1 score of retinal fluid is 95.50%. CONCLUSION: The OCT image segmentation algorithm based on deep learning is primarily founded on the 2D convolutional network. The 3D network architecture proposed in this paper reduces the influence of category imbalance, realizes end-to-end segmentation of volume images, and achieves optimal segmentation results. The segmentation maps are practically the same as the manual annotations of doctors, and can provide doctors with more accurate diagnostic data. 展开更多
关键词 optical COHERENCE tomography IMAGES FLUID segmentation 2D fully convolutional NETWORK 3D fully convolutional NETWORK
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新型5,6-二氢吡啶并[2,3-d]嘧啶-4,7(3H,8H)-二酮类衍生物的设计、合成及抗结核活性研究
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作者 孙连奇 彭孝炯 +2 位作者 寇世博 易红 李卓荣 《中国药物化学杂志》 2025年第2期81-91,共11页
目的设计合成一系列新型嘧啶酮类衍生物,以期得到抗结核分枝杆菌敏感菌株H37Rv及耐药菌株14862活性都较好的新化合物。方法以氰基乙酸乙酯和硫脲为起始原料,通过三步或四步反应,得到目标化合物f1~f31。采用H37Rv对所有目标化合物进行抗... 目的设计合成一系列新型嘧啶酮类衍生物,以期得到抗结核分枝杆菌敏感菌株H37Rv及耐药菌株14862活性都较好的新化合物。方法以氰基乙酸乙酯和硫脲为起始原料,通过三步或四步反应,得到目标化合物f1~f31。采用H37Rv对所有目标化合物进行抗结核活性评价,并对其中活性较好的化合物进行抗耐药菌株14862的活性评价。采用Vero细胞进行安全性评价。结果与结论共合成了31个新化合物,其结构均经^(1)H-NMR、^(13)C-NMR和LC-MS谱确证。其中化合物f11和f28对H37Rv的MIC值分别为0.62μg·mL^(-1)和0.91μg·mL^(-1),表现出较强的抗结核活性,但对耐药菌株14862的活性弱于H37Rv。本研究进一步丰富了该系列化合物的构效关系,以期为后续新型嘧啶酮类化合物的设计提供参考。 展开更多
关键词 5 6-二氢吡啶并[2 3-d]嘧啶-4 7(3H 8H)-二酮类衍生物 抗结核分枝杆菌 结构修饰 构效关系
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Improved Medical Image Segmentation Model Based on 3D U-Net 被引量:2
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作者 LIN Wei FAN Hong +3 位作者 HU Chenxi YANG Yi YU Suping NI Lin 《Journal of Donghua University(English Edition)》 CAS 2022年第4期311-316,共6页
With the widespread application of deep learning in the field of computer vision,gradually allowing medical image technology to assist doctors in making diagnoses has great practical and research significance.Aiming a... With the widespread application of deep learning in the field of computer vision,gradually allowing medical image technology to assist doctors in making diagnoses has great practical and research significance.Aiming at the shortcomings of the traditional U-Net model in 3D spatial information extraction,model over-fitting,and low degree of semantic information fusion,an improved medical image segmentation model has been used to achieve more accurate segmentation of medical images.In this model,we make full use of the residual network(ResNet)to solve the over-fitting problem.In order to process and aggregate data at different scales,the inception network is used instead of the traditional convolutional layer,and the dilated convolution is used to increase the receptive field.The conditional random field(CRF)can complete the contour refinement work.Compared with the traditional 3D U-Net network,the segmentation accuracy of the improved liver and tumor images increases by 2.89%and 7.66%,respectively.As a part of the image processing process,the method in this paper not only can be used for medical image segmentation,but also can lay the foundation for subsequent image 3D reconstruction work. 展开更多
关键词 medical image segmentation 3D U-Net residual network(ResNet) inception model conditional random field(CRF)
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Three-dimensional diabetic macular edema thickness maps based on fluid segmentation and fovea detection using deep learning 被引量:1
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作者 Jing-Jing Xu Yang Zhou +8 位作者 Qi-Jie Wei Kang Li Zhen-Ping Li Tian Yu Jian-Chun Zhao Da-Yong Ding Xi-Rong Li Guang-Zhi Wang Hong Dai 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2022年第3期495-501,共7页
AIM: To explore a more accurate quantifying diagnosis method of diabetic macular edema(DME) by displaying detailed 3D morphometry beyond the gold-standard quantification indicator-central retinal thickness(CRT) and ap... AIM: To explore a more accurate quantifying diagnosis method of diabetic macular edema(DME) by displaying detailed 3D morphometry beyond the gold-standard quantification indicator-central retinal thickness(CRT) and apply it in follow-up of DME patients.METHODS: Optical coherence tomography(OCT) scans of 229 eyes from 160 patients were collected.We manually annotated cystoid macular edema(CME), subretinal fluid(SRF) and fovea as ground truths.Deep convolution neural networks(DCNNs) were constructed including U-Net, sASPP, HRNetV2-W48, and HRNetV2-W48+Object-Contextual Representation(OCR) for fluid(CME+SRF) segmentation and fovea detection respectively, based on which the thickness maps of CME, SRF and retina were generated and divided by Early Treatment Diabetic Retinopathy Study(ETDRS) grid.RESULTS: In fluid segmentation, with the best DCNN constructed and loss function, the dice similarity coefficients(DSC) of segmentation reached 0.78(CME), 0.82(SRF), and 0.95(retina).In fovea detection, the average deviation between the predicted fovea and the ground truth reached 145.7±117.8 μm.The generated macular edema thickness maps are able to discover center-involved DME by intuitive morphometry and fluid volume, which is ignored by the traditional definition of CRT>250 μm.Thickness maps could also help to discover fluid above or below the fovea center ignored or underestimated by a single OCT B-scan.CONCLUSION: Compared to the traditional unidimensional indicator-CRT, 3D macular edema thickness maps are able to display more intuitive morphometry and detailed statistics of DME, supporting more accurate diagnoses and follow-up of DME patients. 展开更多
关键词 diabetic macular edema fluid segmentation fovea detection 3D macular edema thickness maps deep learning
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A Semi-automatic method for segmentation and 3D modeling of glioma tumors from brain MRI 被引量:1
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作者 S. Ananda Resmi Tessamma Thomas 《Journal of Biomedical Science and Engineering》 2012年第7期378-383,共6页
This work presents an efficient method for volume rendering of glioma tumors from segmented 2D MRI Datasets with user interactive control, by replacing manual segmentation required in the state of art methods. The mos... This work presents an efficient method for volume rendering of glioma tumors from segmented 2D MRI Datasets with user interactive control, by replacing manual segmentation required in the state of art methods. The most common primary brain tumors are gliomas, evolving from the cerebral supportive cells. For clinical follow-up, the evaluation of the preoperative tumor volume is essential. Tumor portions were automatically segmented from 2D MR images using morphological filtering techniques. These segmented tumor slices were propagated and modeled with the software package. The 3D modeled tumor consists of gray level values of the original image with exact tumor boundary. Axial slices of FLAIR and T2 weighted images were used for extracting tumors. Volumetric assessment of tumor volume with manual segmentation of its outlines is a time-consuming process and is prone to error. These defects are overcome in this method. Authors verified the performance of our method on several sets of MRI scans. The 3D modeling was also done using segmented 2D slices with the help of medical software package called 3D DOCTOR for verification purposes. The results were validated with the ground truth models by the Radiologist. 展开更多
关键词 3D Modeling GLIOMA TUMOR segmentation VOLUMETRIC Analysis Brain MRI
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Deep Learning-Based 3D Instance and Semantic Segmentation: A Review 被引量:1
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作者 Siddiqui Muhammad Yasir Hyunsik Ahn 《Journal on Artificial Intelligence》 2022年第2期99-114,共16页
The process of segmenting point cloud data into several homogeneous areas with points in the same region having the same attributes is known as 3D segmentation.Segmentation is challenging with point cloud data due to... The process of segmenting point cloud data into several homogeneous areas with points in the same region having the same attributes is known as 3D segmentation.Segmentation is challenging with point cloud data due to substantial redundancy,fluctuating sample density and lack of apparent organization.The research area has a wide range of robotics applications,including intelligent vehicles,autonomous mapping and navigation.A number of researchers have introduced various methodologies and algorithms.Deep learning has been successfully used to a spectrum of 2D vision domains as a prevailing A.I.methods.However,due to the specific problems of processing point clouds with deep neural networks,deep learning on point clouds is still in its initial stages.This study examines many strategies that have been presented to 3D instance and semantic segmentation and gives a complete assessment of current developments in deep learning-based 3D segmentation.In these approaches’benefits,draw backs,and design mechanisms are studied and addressed.This study evaluates the impact of various segmentation algorithms on competitiveness on various publicly accessible datasets,as well as the most often used pipelines,their advantages and limits,insightful findings and intriguing future research directions. 展开更多
关键词 Artificial intelligence computer vision robot vision 3D instance segmentation 3D semantic segmentation 3D data deep learning point cloud MESH VOXEL RGB-d segmentation
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Autonomous nighttime navigation with lunar polarized light:A 3-D attitude determination approach
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作者 Taihang CHEN Jiankai YIN +4 位作者 Pengwei HU Xiao ZHANG Xiang YU Huai-ning WU Lei GUO 《Chinese Journal of Aeronautics》 2025年第11期384-395,共12页
Nighttime navigation faces challenges from limited data and interference,especially when satellite signals are unavailable.Leveraging lunar polarized light,polarization navigation offers a promising solution for night... Nighttime navigation faces challenges from limited data and interference,especially when satellite signals are unavailable.Leveraging lunar polarized light,polarization navigation offers a promising solution for nighttime autonomous navigation.Current algorithms,however,are limited by the requirement for known horizontal attitudes,restricting applications.This study introduces an autonomous 3-D attitude determination method to overcome this limitation.Our approach utilizes the Angle of Polarization(AOP)at night to extract neutral points from the AOP pattern.This allows for the calculation of polarization meridian plane information for attitude determination.Subsequently,we present an optimized Polarization TRIAD(Pol-TRIAD)algorithm to acquire the 3-D attitude.The proposed method outperforms the existing approaches in outdoor experiments by achieving lower Root Mean Square Error(RMSE).For one baseline attitude,it improves pitch by 31.7%,roll by 21.7%,and yaw by 2.6%,while for the attitude with a larger tilt angle,the improvements are 64.4%,30.4%,and 9.1%,respectively. 展开更多
关键词 3-d attitude determination Lunar polarized light Neutral points Night navigation Polarization
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