A new compound. methyl 4. 6-O-benzylidene-a-D-glucopyranoside 2. 3-cyclicphosphite ethyl ester was synthesized via the reaction of methyl 4. 6-O-benzylidene-a-D-glucopyranoside and ethyl dichlorophosphite. Its structu...A new compound. methyl 4. 6-O-benzylidene-a-D-glucopyranoside 2. 3-cyclicphosphite ethyl ester was synthesized via the reaction of methyl 4. 6-O-benzylidene-a-D-glucopyranoside and ethyl dichlorophosphite. Its structure was confirmed by NMR and MSspectral methods.展开更多
The membrane-anchored myelin enzyme 2′,3′-cyclic nucleotide 3′-phosphodiesterase（CNPase） was discovered in the early 1960 s and has since then troubled scientists with its peculiar catalytic activity and high exp...The membrane-anchored myelin enzyme 2′,3′-cyclic nucleotide 3′-phosphodiesterase（CNPase） was discovered in the early 1960 s and has since then troubled scientists with its peculiar catalytic activity and high expression levels in the central nervous system. Despite decades of research, the actual physiological relevance of CNPase has only recently begun to unravel. In addition to a role in myelination, CNPase is also involved in local adenosine production in traumatic brain injury and possibly has a regulatory function in mitochondrial membrane permeabilization. Although research focusing on the CNPase phosphodiesterase activity has been helpful, several open questions concerning the protein function in vivo remain unanswered. This review is focused on past research on CNPase, especially in the fields of structural biology and enzymology, and outlines the current understanding regarding the biochemical and physiological significance of CNPase, providing ideas and directions for future research.展开更多
在面向“双碳”目标的废弃物资源化利用进程中,废塑料气化合成气因其富碳氢特性与负碳潜力成为新兴技术焦点。相比于传统焚烧或填埋导致碳资源耗散与二次污染,气化技术将聚烯烃类废弃物定向转化为高纯度合成气,具备低污染、经济效益高...在面向“双碳”目标的废弃物资源化利用进程中,废塑料气化合成气因其富碳氢特性与负碳潜力成为新兴技术焦点。相比于传统焚烧或填埋导致碳资源耗散与二次污染,气化技术将聚烯烃类废弃物定向转化为高纯度合成气,具备低污染、经济效益高、灵活性强等优势,为废弃物高值化利用与绿氢联产提供了关键路径,在实现资源循环和减少环境污染方面有着显著效应。针对常规气化产物气品质不高、催化剂易失活等问题,提出了废塑料分级热解–化学链气化(Staged Chemical Looping Gasification,SCLG)工艺,采用溶胶凝胶法合成的典型钙钛矿LaFeO_(3)载氧体,在固定床反应系统上开展了聚丙烯气化试验研究,考察热解温度、气化温度、LaFeO_(3)(OC)与聚丙烯(PP)质量比对LaFeO_(3)载氧体气化性能的影响机理。该工艺将原料和载氧体分离,能有效避免传统一段式气化工艺中催化剂易被固体残渣、焦炭和焦油污染问题,此外分级反应充分发挥了载氧体的部分氧化能力和还原金属的催化裂解能力,有效提高了合成气的产率和品质。结果表明:热解温度对气化效果的影响较小,而适当提升气化温度效果显著,合适的m(OC):m(PP)能较好地平衡氧化重整和催化裂解两步反应,具备较好的气化效果。在600℃热解温度、850℃气化温度以及m(OC):m(PP)为1:1的反应条件下具有最佳的气化效果,此时合成气产率为.143 mmol/g,碳转化率达82%,CO选择性为80%,并具有较好的循环稳定性。为废塑料资源化及高效稳定气化技术的规模化发展提供了指导。展开更多
The interaction sites between microperoxidase-8(MP-8) and Eu^3+ was determined using electrochemical techniques. It is found that two Eu^3+ ions would coordinate strongly with carboxylate oxygen of two propionic acid ...The interaction sites between microperoxidase-8(MP-8) and Eu^3+ was determined using electrochemical techniques. It is found that two Eu^3+ ions would coordinate strongly with carboxylate oxygen of two propionic acid groups of the heme group in an MP-8 molecule, leading to the increase in the reversibility of the electrochemical reaction of MP-8. The excessive Eu^3+ ions weakly interact with the oxygen containing groups in the peptide chain of MP-8.展开更多
文摘A new compound. methyl 4. 6-O-benzylidene-a-D-glucopyranoside 2. 3-cyclicphosphite ethyl ester was synthesized via the reaction of methyl 4. 6-O-benzylidene-a-D-glucopyranoside and ethyl dichlorophosphite. Its structure was confirmed by NMR and MSspectral methods.
基金supported by grants from the Department of Biochemistry,University of Ouluthe Sigrid Jusélius Foundation (Finland)+1 种基金the Academy of Finlandthe Hamburg Research and Science Foundation (Germany)
文摘The membrane-anchored myelin enzyme 2′,3′-cyclic nucleotide 3′-phosphodiesterase（CNPase） was discovered in the early 1960 s and has since then troubled scientists with its peculiar catalytic activity and high expression levels in the central nervous system. Despite decades of research, the actual physiological relevance of CNPase has only recently begun to unravel. In addition to a role in myelination, CNPase is also involved in local adenosine production in traumatic brain injury and possibly has a regulatory function in mitochondrial membrane permeabilization. Although research focusing on the CNPase phosphodiesterase activity has been helpful, several open questions concerning the protein function in vivo remain unanswered. This review is focused on past research on CNPase, especially in the fields of structural biology and enzymology, and outlines the current understanding regarding the biochemical and physiological significance of CNPase, providing ideas and directions for future research.
文摘在面向“双碳”目标的废弃物资源化利用进程中,废塑料气化合成气因其富碳氢特性与负碳潜力成为新兴技术焦点。相比于传统焚烧或填埋导致碳资源耗散与二次污染,气化技术将聚烯烃类废弃物定向转化为高纯度合成气,具备低污染、经济效益高、灵活性强等优势,为废弃物高值化利用与绿氢联产提供了关键路径,在实现资源循环和减少环境污染方面有着显著效应。针对常规气化产物气品质不高、催化剂易失活等问题,提出了废塑料分级热解–化学链气化(Staged Chemical Looping Gasification,SCLG)工艺,采用溶胶凝胶法合成的典型钙钛矿LaFeO_(3)载氧体,在固定床反应系统上开展了聚丙烯气化试验研究,考察热解温度、气化温度、LaFeO_(3)(OC)与聚丙烯(PP)质量比对LaFeO_(3)载氧体气化性能的影响机理。该工艺将原料和载氧体分离,能有效避免传统一段式气化工艺中催化剂易被固体残渣、焦炭和焦油污染问题,此外分级反应充分发挥了载氧体的部分氧化能力和还原金属的催化裂解能力,有效提高了合成气的产率和品质。结果表明:热解温度对气化效果的影响较小,而适当提升气化温度效果显著,合适的m(OC):m(PP)能较好地平衡氧化重整和催化裂解两步反应,具备较好的气化效果。在600℃热解温度、850℃气化温度以及m(OC):m(PP)为1:1的反应条件下具有最佳的气化效果,此时合成气产率为.143 mmol/g,碳转化率达82%,CO选择性为80%,并具有较好的循环稳定性。为废塑料资源化及高效稳定气化技术的规模化发展提供了指导。
文摘The interaction sites between microperoxidase-8(MP-8) and Eu^3+ was determined using electrochemical techniques. It is found that two Eu^3+ ions would coordinate strongly with carboxylate oxygen of two propionic acid groups of the heme group in an MP-8 molecule, leading to the increase in the reversibility of the electrochemical reaction of MP-8. The excessive Eu^3+ ions weakly interact with the oxygen containing groups in the peptide chain of MP-8.
