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Development of Patient-Derived Conditionally Reprogrammed 3D Breast Cancer Culture Models for Drug Sensitivity Evaluation
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作者 Jing Cai Haoyun Zhu +4 位作者 Weiling Guo Ting Huang Pangzhou Chen Wen Zhou Ziyun Guan 《Oncology Research》 2026年第1期500-520,共21页
Background:Therapeutic responses of breast cancer vary among patients and lead to drug resistance and recurrence due to the heterogeneity.Current preclinical models,however,are inadequate for predicting individual pat... Background:Therapeutic responses of breast cancer vary among patients and lead to drug resistance and recurrence due to the heterogeneity.Current preclinical models,however,are inadequate for predicting individual patient responses towards different drugs.This study aimed to investigate the patient-derived breast cancer culture models for drug sensitivity evaluations.Methods:Tumor and adjacent tissues from female breast cancer patients were collected during surgery.Patient-derived breast cancer cells were cultured using the conditional reprogramming technique to establish 2D models.The obtained patient-derived conditional reprogramming breast cancer(CRBC)cells were subsequently embedded in alginate-gelatin methacryloyl hydrogel microspheres to form 3D culture models.Comparisons between 2D and 3D models were made using immunohistochemistry(tumor markers),MTS assays(cell viability),flow cytometry(apoptosis),transwell assays(migration),and Western blotting(protein expression).Drug sensitivity tests were conducted to evaluate patient-specific responses to anti-cancer agents.Results:2D and 3D culture models were successfully established using samples from eight patients.The 3D models retained histological and marker characteristics of the original tumors.Compared to 2D cultures,3D models exhibited increased apoptosis,enhanced drug resistance,elevated stem cell marker expression,and greater migration ability—features more reflective of in vivo tumor behavior.Conclusion:Patient-derived 3D CRBC models effectively mimic the in vivo tumor microenvironment and demonstrate stronger resistance to anti-cancer drugs than 2D models.These hydrogel-based models offer a cost-effective and clinically relevant platform for drug screening and personalized breast cancer treatment. 展开更多
关键词 Patient-derived breast cancer cells conditional reprogramming hydrogel microsphere 3d culture model drug screening
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Integrating geographic information system and 3D virtual reality for optimized modeling of large-scale photovoltaic wind hybrid system:A case study in Dakhla City,Morocco 被引量:1
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作者 Elmostafa Achbab Rachid Lambarki +1 位作者 Hassan Rhinane Dennoun Saifaoui 《Energy Geoscience》 2025年第2期174-193,共20页
This research pioneers the integration of geographic information systems(GIS)and 3D modeling within a virtual reality(VR)framework to assess the viability and planning of a 20 MW hybrid wind-solarphotovoltaic(PV)syste... This research pioneers the integration of geographic information systems(GIS)and 3D modeling within a virtual reality(VR)framework to assess the viability and planning of a 20 MW hybrid wind-solarphotovoltaic(PV)system connected to the local grid.The study focuses on Dakhla,Morocco,a region with vast untapped renewable energy potential.By leveraging GIS,we are innovatively analyzing geographical and environmental factors that influence optimal site selection and system design.The incorporation of VR technologies offers an unprecedented level of realism and immersion,allowing stakeholders to virtually experience the project's impact and design in a dynamic,interactive environment.This novel methodology includes extensive data collection,advanced modeling,and simulations,ensuring that the hybrid system is precisely tailored to the unique climatic and environmental conditions of Dakhla.Our analysis reveals that the region possesses a photovoltaic solar potential of approximately2400 k Wh/m^(2) per year,with an average annual wind power density of about 434 W/m^(2) at an 80-meter hub height.Productivity simulations indicate that the 20 MW hybrid system could generate approximately 60 GWh of energy per year and 1369 GWh over its 25-year lifespan.To validate these findings,we employed the System Advisor Model(SAM)software and the Global Solar Photovoltaic Atlas platform.This comprehensive and interdisciplinary approach not only provides a robust assessment of the system's feasibility but also offers valuable insights into its potential socio-economic and environmental impact. 展开更多
关键词 Geographic information systems 3d virtual reality(VR)modeling Wind energy Solar photovoltaic(PV)energy Hybrid renewable energy system assessment
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Vector Extraction from Design Drawings for Intelligent 3D Modeling of Transmission Towers
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作者 Ziqiang Tang Chao Han +5 位作者 Hongwu Li Zhou Fan Ke Sun Yuntian Huang Yuhang Chen Chenxing Wang 《Computers, Materials & Continua》 2025年第2期2813-2829,共17页
Accurate vector extraction from design drawings is required first to automatically create 3D models from pixel-level engineering design drawings. However, this task faces the challenges of complicated design shapes as... Accurate vector extraction from design drawings is required first to automatically create 3D models from pixel-level engineering design drawings. However, this task faces the challenges of complicated design shapes as well as cumbersome and cluttered annotations on drawings, which interfere with the vector extraction heavily. In this article, the transmission tower containing the most complex structure is taken as the research object, and a semantic segmentation network is constructed to first segment the shape masks from the pixel-level drawings. Preprocessing and postprocessing are also proposed to ensure the stability and accuracy of the shape mask segmentation. Then, based on the obtained shape masks, a vector extraction network guided by heatmaps is designed to extract structural vectors by fusing the features from node heatmap and skeleton heatmap, respectively. Compared with the state-of-the-art methods, experiment results illustrate that the proposed semantic segmentation method can effectively eliminate the interference of many elements on drawings to segment the shape masks effectively, meanwhile, the model trained by the proposed vector extraction network can accurately extract the vectors such as nodes and line connections, avoiding redundant vector detection. The proposed method lays a solid foundation for automatic 3D model reconstruction and contributes to technological advancements in relevant fields. 展开更多
关键词 design drawings semantic segmentation deep learning vector extraction dIGITIZATION 3d modeling
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3D Computational Modeling and Stability Analysis of Highway Slope:A Case Study from the X104 Section in Ganxian County
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作者 Fujie Dai Yiwen Jin +1 位作者 Yongliang Wang Jiajun Li 《Journal of Electronic Research and Application》 2025年第2期65-68,共4页
Highway planning requires geological surveys and stability analysis of the surrounding area.In the early stage of the survey,the modeling and stability analysis of the survey area can be carried out by using GIS softw... Highway planning requires geological surveys and stability analysis of the surrounding area.In the early stage of the survey,the modeling and stability analysis of the survey area can be carried out by using GIS software to intuitively understand the topography of the study area.The use of DEM to extract terrain factors can be used for simple stability analysis and the source data is easy to obtain,simple to operate,fast to analyze,and reliable analysis results.In this paper,taking the X104 road section in Ganxian County as an example,the ArcGIS platform is used to carry out 3D modeling visualization and stability analysis,and the stability evaluation map of the study area is obtained. 展开更多
关键词 3d modeling STABILITY GIS Highway planning
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A novel heuristic pathfinding algorithm for 3D security modeling and vulnerability assessment
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作者 Jun Yang Yue-Ming Hong +2 位作者 Yu-Ming Lv Hao-Ming Ma Wen-Lin Wang 《Nuclear Science and Techniques》 2025年第5期152-166,共15页
Vulnerability assessment is a systematic process to identify security gaps in the design and evaluation of physical protection systems.Adversarial path planning is a widely used method for identifying potential vulner... Vulnerability assessment is a systematic process to identify security gaps in the design and evaluation of physical protection systems.Adversarial path planning is a widely used method for identifying potential vulnerabilities and threats to the security and resilience of critical infrastructures.However,achieving efficient path optimization in complex large-scale three-dimensional(3D)scenes remains a significant challenge for vulnerability assessment.This paper introduces a novel A^(*)-algorithmic framework for 3D security modeling and vulnerability assessment.Within this framework,the 3D facility models were first developed in 3ds Max and then incorporated into Unity for A^(*)heuristic pathfinding.The A^(*)-heuristic pathfinding algorithm was implemented with a geometric probability model to refine the detection and distance fields and achieve a rational approximation of the cost to reach the goal.An admissible heuristic is ensured by incorporating the minimum probability of detection(P_(D)^(min))and diagonal distance to estimate the heuristic function.The 3D A^(*)heuristic search was demonstrated using a hypothetical laboratory facility,where a comparison was also carried out between the A^(*)and Dijkstra algorithms for optimal path identification.Comparative results indicate that the proposed A^(*)-heuristic algorithm effectively identifies the most vulnerable adversarial pathfinding with high efficiency.Finally,the paper discusses hidden phenomena and open issues in efficient 3D pathfinding for security applications. 展开更多
关键词 Physical protection system 3d modeling and simulation Vulnerability assessment A^(*)Heuristic Pathfinding dijkstra algorithm
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Cavity 3D modeling and correlative techniques based on cavity monitoring 被引量:25
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作者 罗周全 刘晓明 +2 位作者 张保 鹿浩 李畅 《Journal of Central South University of Technology》 EI 2008年第5期639-644,共6页
According to the mining method for Dongguashan Copper Mine and Tongkeng Mine in China, and with the help of the cavity monitoring system(CMS) and mining software Surpac, the 3D cavity models were established exactly... According to the mining method for Dongguashan Copper Mine and Tongkeng Mine in China, and with the help of the cavity monitoring system(CMS) and mining software Surpac, the 3D cavity models were established exactly. A series of correlative techniques for calculating stope over-excavation and under-excavation, stope dilution and ore loss rates, and the blasting design of the pillar with complicated irregular boundaries were developed. These techniques were applied in Dongguashan Copper Mine and Tongkeng Mine successfully. Using these techniques, the dilution rates of stopes 52-2^#, 52-6^#, 52-8^#and 52-10^# of Dongguashan Copper Mine are calculated to be 2.12%, 8.46%, 12-67% and 10.68%, respectively, and the ore loss rates of stopes 52-6^# and 5-8^# are 4.41% and 3.70%, severally. Furthermore, according to the design accomplished by the technique for a pillar of Tongkeng Mine with irregular boundary, the volume, total length of boreholes and the dynamite quantity of the pillar are computed to be 1.2 ×10^4 m^3, 2.98 km and 10.97 t, correspondingly. 展开更多
关键词 cavity 3d modeling cavity monitoring system STOPE dILUTION loss rate pillar blasting
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The parallel 3D magnetotelluric forward modeling algorithm 被引量:28
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作者 Tan Handong Tong Tuo Lin Changhong 《Applied Geophysics》 SCIE CSCD 2006年第4期197-202,共6页
The workload of the 3D magnetotelluric forward modeling algorithm is so large that the traditional serial algorithm costs an extremely large compute time. However, the 3D forward modeling algorithm can process the dat... The workload of the 3D magnetotelluric forward modeling algorithm is so large that the traditional serial algorithm costs an extremely large compute time. However, the 3D forward modeling algorithm can process the data in the frequency domain, which is very suitable for parallel computation. With the advantage of MPI and based on an analysis of the flow of the 3D magnetotelluric serial forward algorithm, we suggest the idea of parallel computation and apply it. Three theoretical models are tested and the execution efficiency is compared in different situations. The results indicate that the parallel 3D forward modeling computation is correct and the efficiency is greatly improved. This method is suitable for large size geophysical computations. 展开更多
关键词 Magnetotelluric 3d forward modeling MPI parallel programming design 3d staggered-grid finite difference method parallel algorithm.
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Patterns and Dynamics of Rifting on Passive Continental Margin from Shelf to Slope of the Northern South China Sea:Evidence from 3D Analogue Modeling 被引量:14
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作者 孙珍 周蒂 +4 位作者 吴世敏 钟志洪 Myra Keep 姜建群 樊浩 《Journal of China University of Geosciences》 SCIE CSCD 2009年第1期136-146,共11页
Affected by thermal perturbation due to mantle uprising, the rheological structure of the lithosphere could be modified, which could lead to different rifting patterns from shelf to slope in a passive continental marg... Affected by thermal perturbation due to mantle uprising, the rheological structure of the lithosphere could be modified, which could lead to different rifting patterns from shelf to slope in a passive continental margin. From the observed deformation style on the northern South China Sea and analogue modeling experiments, we find that the rift zone located on the shelf is characterized by half grabens or simple grabens controlled mainly by long faults with large vertical offset, supposed to be formed with normal lithosphere extension. On the slope, where the lithosphere is very hot due to mantle upweUing and heating, composite grabens composed of symmetric grabens developed. The boundary and inner faults are all short with small vertical offset. Between the zones with very hot and normal lithosphere, composite half grabens composed of half grabens or asymmetric grabens formed, whose boundary faults are long with large vertical offset, while the inner faults are relatively short. Along with the thickness decrease of the brittle upper crust due to high temperature, the deformation becomes more sensitive to the shape of a pre-existing weakness zone and shows orientation variation along strike. When there was a bend in the pre-existing weakness zone, and the basal plate was pulled by a clockwise rotating stress, the strongest deformation always occurs along the middle segment and at the transition area from the middle to the eastern segments, which contributes to a hotter lithosphere in the middle segment, where the Baiyun (白云) sag formed. 展开更多
关键词 passive continental margin rifting pattern 3d analogue modeling South China Sea.
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Building Information Modeling-Based Secondary Development System for 3D Modeling of Underground Pipelines 被引量:5
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作者 Jun Chen Rao Hu +1 位作者 Xianfeng Guo Feng Wu 《Computer Modeling in Engineering & Sciences》 SCIE EI 2020年第5期647-660,共14页
Underground pipeline networks constitute a major component of urban infrastructure,and thus,it is imperative to have an efficient mechanism to manage them.This study introduces a secondary development system to effici... Underground pipeline networks constitute a major component of urban infrastructure,and thus,it is imperative to have an efficient mechanism to manage them.This study introduces a secondary development system to efficiently model underground pipeline networks,using the building information modeling(BIM)-based software Revit.The system comprises separate pipe point and tubulation models.Using a Revit application programming interface(API),the spatial position and attribute data of the pipe points are extracted from a pipeline database,and the corresponding tubulation data are extracted from a tubulation database.Using the Family class in Revit API,the cluster in the self-built library of pipe point is inserted into the spatial location and the attribute data is added;in the same way,all pipeline instances in the pipeline system are created.The extension and localization of the model accelerated the modeling speed.The system was then used in a real construction project.The expansion of the model database and rapid modeling made the application of BIM technology in three-dimensional visualization of underground pipeline networks more convenient.Furthermore,it has applications in pipeline engineering construction and management. 展开更多
关键词 Building information modeling secondary development underground pipeline 3d modeling visualization.
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Integrating deep learning and logging data analytics for lithofacies classification and 3D modeling of tight sandstone reservoirs 被引量:4
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作者 Jing-Jing Liu Jian-Chao Liu 《Geoscience Frontiers》 SCIE CAS CSCD 2022年第1期350-363,共14页
The lithofacies classification is essential for oil and gas reservoir exploration and development.The traditional method of lithofacies classification is based on"core calibration logging"and the experience ... The lithofacies classification is essential for oil and gas reservoir exploration and development.The traditional method of lithofacies classification is based on"core calibration logging"and the experience of geologists.This approach has strong subjectivity,low efficiency,and high uncertainty.This uncertainty may be one of the key factors affecting the results of 3 D modeling of tight sandstone reservoirs.In recent years,deep learning,which is a cutting-edge artificial intelligence technology,has attracted attention from various fields.However,the study of deep-learning techniques in the field of lithofacies classification has not been sufficient.Therefore,this paper proposes a novel hybrid deep-learning model based on the efficient data feature-extraction ability of convolutional neural networks(CNN)and the excellent ability to describe time-dependent features of long short-term memory networks(LSTM)to conduct lithological facies-classification experiments.The results of a series of experiments show that the hybrid CNN-LSTM model had an average accuracy of 87.3%and the best classification effect compared to the CNN,LSTM or the three commonly used machine learning models(Support vector machine,random forest,and gradient boosting decision tree).In addition,the borderline synthetic minority oversampling technique(BSMOTE)is introduced to address the class-imbalance issue of raw data.The results show that processed data balance can significantly improve the accuracy of lithofacies classification.Beside that,based on the fine lithofacies constraints,the sequential indicator simulation method is used to establish a three-dimensional lithofacies model,which completes the fine description of the spatial distribution of tight sandstone reservoirs in the study area.According to this comprehensive analysis,the proposed CNN-LSTM model,which eliminates class imbalance,can be effectively applied to lithofacies classification,and is expected to improve the reality of the geological model for the tight sandstone reservoirs. 展开更多
关键词 deep learning Convolutional neural networks LSTM Lithological-facies classification 3d modeling Class imbalance
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From the Area to the Point-Study on the Key Technology of 3D Geological Hazard Modeling in Three Gorges Reservoir Area 被引量:9
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作者 刘军旗 黄学斌 +3 位作者 吴冲龙 程温鸣 项伟 夏鹤 《Journal of Earth Science》 SCIE CAS CSCD 2012年第2期199-206,共8页
Taking hundreds of pieces of hazardous geological maps (1 : 10 000) of Three Gorges res-ervoir area (3GR) as background, we establish regional three-dimensional (3D) geo-hazard modelusing DEM (digital elevatio... Taking hundreds of pieces of hazardous geological maps (1 : 10 000) of Three Gorges res-ervoir area (3GR) as background, we establish regional three-dimensional (3D) geo-hazard modelusing DEM (digital elevation model) superposed surface images and geo-hazards elements. Based on landslides and other geo-hazard survey data,using improved B-REP(boundary representa-tion)entity data structure (two-body 3D data structure), we set up 3D solid models for each hazardous bodies in each hazardous geological maps. Then we integrate the two types of 3D models with different scales from area to point, which are the regional geo-hazard 3D model and the solid models of each disaster body, in order to provide a visual processing and analysis plat-form for danger partition, stability evaluation, disaster prevention and control, early warning and command. 展开更多
关键词 investigation database regional 3d geological model three-dimensional solid model of disaster body disaster prevention and control early warning command.
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Research on 3D Distribution of Meandering River Sand Body Using Sedimentary Facies Method and 3D Geological Modeling 被引量:8
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作者 WU Jian CAO Dai-yong 《Journal of China University of Mining and Technology》 EI 2006年第3期349-352,共4页
Sedimentary facies study is an important method in describing the property and distribution of reservoir. 3D geological modeling is a powerful tool in 3D characterization of geological bodies. By combining the sedimen... Sedimentary facies study is an important method in describing the property and distribution of reservoir. 3D geological modeling is a powerful tool in 3D characterization of geological bodies. By combining the sedimentary facies study with 3D geological modeling to generate 3D sedimentary facies model, the 3D geometry and distribution feature of sand bodies can be more accurately characterized, particularly in 3D view. In Liuchu oilfield of Jizhong depression, the Ed2IV formation was recognized as meandering river deposition facies and five sedimentary facies were identified, which include point bar sand, levee, channel margin, abandoned channel and floodplain. All the 24 sand body facies in Ed2IV were mapped and the 3D sedimentary facies model established based on 2D facies maps. The result shows that the 3D sedimentary facies model is well matched for the research result of sedimentary facies. Being an extension of traditional sedimentary study, the 3D sedimentary facies model can be used to describe the 3D geometry and distribution orders of a single sand body more reliably and more accurately. 展开更多
关键词 sedimentary facies meandering river 3d model geostatistic simulation
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3D Micromechanical Modeling of Failure and Damage Evolution in Dual Phase Steel Based on a Real 2D Microstructure 被引量:3
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作者 M.R.Ayatollahi A.Ch.Darabi +1 位作者 H.R.Chamani J.Kadkhodapour 《Acta Mechanica Solida Sinica》 SCIE EI CSCD 2016年第1期95-110,共16页
A plate of dual phase steel was produced from low carbon steel with intercritical annealing treatment. Its optically determined surface microstructure was utilized to construct three different microstructural models. ... A plate of dual phase steel was produced from low carbon steel with intercritical annealing treatment. Its optically determined surface microstructure was utilized to construct three different microstructural models. To describe the ductile damage in the ferritic matrix, the Gurson-Tvergaard-Needleman model was used with the failure in the martensite phase being ignored. The numerical results obtained for the mechanism of void initiation and coalescence were compared with the experimental observations. The numerical results obtained from the randomly extruded 3D model showed a significantly better agreement with the experimental ones than those obtained from the 2D model or the uniformly extruded 3D model. 展开更多
关键词 dual phase steel 3d model MICROSTRUCTURE micromechanical modeling GTN dam-age model
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An Approach to Computer Modeling of Geological Faults in 3D and an Application 被引量:10
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作者 ZHU Liang-feng HE Zheng PAN Xin WU Xin-cai 《Journal of China University of Mining and Technology》 2006年第4期461-465,共5页
3D geological modeling, one of the most important applications in geosciences of 3D GIS, forms the basis and is a prerequisite for visualized representation and analysis of 3D geological data. Computer modeling of geo... 3D geological modeling, one of the most important applications in geosciences of 3D GIS, forms the basis and is a prerequisite for visualized representation and analysis of 3D geological data. Computer modeling of geological faults in 3D is currently a topical research area. Structural modeling techniques of complex geological entities contain- ing reverse faults are discussed and a series of approaches are proposed. The geological concepts involved in computer modeling and visualization of geological fault in 3D are explained, the type of data of geological faults based on geo- logical exploration is analyzed, and a normative database format for geological faults is designed. Two kinds of model- ing approaches for faults are compared: a modeling technique of faults based on stratum recovery and a modeling tech- nique of faults based on interpolation in subareas. A novel approach, called the Unified Modeling Technique for stratum and fault, is presented to solve the puzzling problems of reverse faults, syn-sedimentary faults and faults terminated within geological models. A case study of a fault model of bed rock in the Beijing Olympic Green District is presented in order to show the practical result of this method. The principle and the process of computer modeling of geological faults in 3D are discussed and a series of applied technical proposals established. It strengthens our profound compre- hension of geological phenomena and the modeling approach, and establishes the basic techniques of 3D geological modeling for practical applications in the field of geosciences. 展开更多
关键词 3d geological modeling geological faults STRATUM fault data visualization Beijing Olympic Green district
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3D modeling of geological anomalies based on segmentation of multiattribute fusion 被引量:2
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作者 Liu Zhi-Ning Song Cheng-Yun +3 位作者 Li Zhi-Yong Cai Han-Peng Yao Xing-Miao Hu Guang-Min 《Applied Geophysics》 SCIE CSCD 2016年第3期519-528,581,共11页
3D modeling of geological bodies based on 3D seismic data is used to define the shape and volume of the bodies, which then can be directly applied to reservoir prediction, reserve estimation, and exploration. However,... 3D modeling of geological bodies based on 3D seismic data is used to define the shape and volume of the bodies, which then can be directly applied to reservoir prediction, reserve estimation, and exploration. However, multiattributes are not effectively used in 3D modeling. To solve this problem, we propose a novel method for building of 3D model of geological anomalies based on the segmentation of multiattribute fusion. First, we divide the seismic attributes into edge- and region-based seismic attributes. Then, the segmentation model incorporating the edge- and region-based models is constructed within the levelset- based framework. Finally, the marching cubes algorithm is adopted to extract the zero level set based on the segmentation results and build the 3D model of the geological anomaly. Combining the edge-and region-based attributes to build the segmentation model, we satisfy the independence requirement and avoid the problem of insufficient data of single seismic attribute in capturing the boundaries of geological anomalies. We apply the proposed method to seismic data from the Sichuan Basin in southwestern China and obtain 3D models of caves and channels. Compared with 3D models obtained based on single seismic attributes, the results are better agreement with reality. 展开更多
关键词 Geological anomaly multiattributes FUSION SEGMENTATION 3d modeling
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Building the 3D seismic fault models for the 2021 M_(S)6.4 Yunnan Yangbi earthquake:The potential role of pre-existing faults in generating unexpected moderate-strong earthquakes in southeast Xizang 被引量:1
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作者 Xiao Sun Jinyu Zhang +4 位作者 Renqi Lu Wei Wang Peng Su Guanshen Liu Fang Xu 《Earthquake Science》 2025年第3期172-186,共15页
The three-dimensional(3D)geometry of a fault is a critical control on earthquake nucleation,dynamic rupture,stress triggering,and related seismic hazards.Therefore,a 3D model of an active fault can significantly impro... The three-dimensional(3D)geometry of a fault is a critical control on earthquake nucleation,dynamic rupture,stress triggering,and related seismic hazards.Therefore,a 3D model of an active fault can significantly improve our understanding of seismogenesis and our ability to evaluate seismic hazards.Utilising the SKUA GoCAD software,we constructed detailed seismic fault models for the 2021 M_(S)6.4 Yangbi earthquake in Yunnan,China,using two sets of relocated earthquake catalogs and focal mechanism solutions following a convenient 3D fault modeling workflow.Our analysis revealed a NW-striking main fault with a high-angle SW dip,accompanied by two branch faults.Interpretation of one dataset revealed a single NNW-striking branch fault SW of the main fault,whereas the other dataset indicated four steep NNE-striking segments with a left-echelon pattern.Additionally,a third ENE-striking short fault was identified NE of the main fault.In combination with the spatial distribution of pre-existing faults,our 3D fault models indicate that the Yangbi earthquake reactivated pre-existing NW-and NE-striking fault directions rather than the surface-exposed Weixi-Qiaohou-Weishan Fault zone.The occurrence of the Yangbi earthquake demonstrates that the reactivation of pre-existing faults away from active fault zones,through either cascade or conjugate rupture modes,can cause unexpected moderate-large earthquakes and severe disasters,necessitating attention in regions like southeast Xizang,which have complex fault systems. 展开更多
关键词 Yangbi earthquake 3d seismogenic fault model relocated earthquakes Weixi-Qiaohou-Weishan fault seismic hazard
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Alternative 3D Modeling Approaches Based on Complex Multi-Source Geological Data Interpretation 被引量:5
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作者 李明超 韩彦青 +1 位作者 缪正建 高伟 《Transactions of Tianjin University》 EI CAS 2014年第1期7-14,共8页
Due to the complex nature of multi-source geological data, it is difficult to rebuild every geological structure through a single 3D modeling method. The multi-source data interpretation method put forward in this ana... Due to the complex nature of multi-source geological data, it is difficult to rebuild every geological structure through a single 3D modeling method. The multi-source data interpretation method put forward in this analysis is based on a database-driven pattern and focuses on the discrete and irregular features of geological data. The geological data from a variety of sources covering a range of accuracy, resolution, quantity and quality are classified and integrated according to their reliability and consistency for 3D modeling. The new interpolation-approximation fitting construction algorithm of geological surfaces with the non-uniform rational B-spline(NURBS) technique is then presented. The NURBS technique can retain the balance among the requirements for accuracy, surface continuity and data storage of geological structures. Finally, four alternative 3D modeling approaches are demonstrated with reference to some examples, which are selected according to the data quantity and accuracy specification. The proposed approaches offer flexible modeling patterns for different practical engineering demands. 展开更多
关键词 multi-source data geological data interpretation interpolation-approximation fitting 3d geological sur-face modeling
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Integrating artificial neural networks and geostatistics for optimum 3D geological block modeling in mineral reserve estimation:A case study 被引量:4
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作者 Jalloh Abu Bakarr Kyuro Sasaki +1 位作者 Jalloh Yaguba Barrie Abubakarr Karim 《International Journal of Mining Science and Technology》 SCIE EI CSCD 2016年第4期581-585,共5页
In this research, a method called ANNMG is presented to integrate Artificial Neural Networks and Geostatistics for optimum mineral reserve evaluation. The word ANNMG simply means Artificial Neural Network Model integr... In this research, a method called ANNMG is presented to integrate Artificial Neural Networks and Geostatistics for optimum mineral reserve evaluation. The word ANNMG simply means Artificial Neural Network Model integrated with Geostatiscs, In this procedure, the Artificial Neural Network was trained, tested and validated using assay values obtained from exploratory drillholes. Next, the validated model was used to generalize mineral grades at known and unknown sampled locations inside the drilling region respectively. Finally, the reproduced and generalized assay values were combined and fed to geostatistics in order to develop a geological 3D block model. The regression analysis revealed that the predicted sample grades were in close proximity to the actual sample grades, The generalized grades from the ANNMG show that this process could be used to complement exploration activities thereby reducing drilling requirement. It could also be an effective mineral reserve evaluation method that could oroduce optimum block model for mine design. 展开更多
关键词 Artificial Neural Network Model with Geostatistics(ANNMG) 3d geological block modeling Mine design KRIGING
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On numerical modeling of low-head direct chill ingot caster for magnesium alloy AZ31 被引量:2
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作者 Mainul Hasan Latifa Begum 《Journal of Magnesium and Alloys》 SCIE EI CAS 2014年第4期275-286,共12页
A comprehensive 3D turbulent CFD study has been carried out to simulate a Low-Head(LH)vertical Direct Chill(DC)rolling ingot caster for the common magnesium alloy AZ31.The model used in this study takes into account t... A comprehensive 3D turbulent CFD study has been carried out to simulate a Low-Head(LH)vertical Direct Chill(DC)rolling ingot caster for the common magnesium alloy AZ31.The model used in this study takes into account the coupled laminar/turbulent melt flow and solidification aspects of the process and is based on the control-volume finite-difference approach.Following the aluminum/magnesium DC casting industrial practices,the LH mold is taken as 30 mm with a hot top of 60 mm.The previously verified in-house code has been modified to model the present casting process.Important quantitative results are obtained for four casting speeds,for three inlet melt pouring temperatures(superheats)and for three metal-mold contact heat transfer coefficients for the steady state operational phase of the caster.The variable cooling water temperatures reported by the industry are considered for the primary and secondary cooling zones during the simulations.Specifically,the temperature and velocity fields,sump depth and sump profiles,mushy region thickness,solid shell thickness at the exit of the mold and axial temperature profiles at the center and at three strategic locations at the surface of the slab are presented and discussed. 展开更多
关键词 Low-head dC caster Magnesium alloy AZ31 3d CFd modeling Turbulent melt flow Solidification Mushy region thickness Sump profile
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Modeling Methods of 3D Model in Digital Twins 被引量:1
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作者 Ruijun Liu Haisheng Li Zhihan Lv 《Computer Modeling in Engineering & Sciences》 SCIE EI 2023年第8期985-1022,共38页
To understand the current application and development of 3D modeling in Digital Twins(DTs),abundant literatures on DTs and 3D modeling are investigated by means of literature review.The transition process from 3D mode... To understand the current application and development of 3D modeling in Digital Twins(DTs),abundant literatures on DTs and 3D modeling are investigated by means of literature review.The transition process from 3D modeling to DTs modeling is analyzed,as well as the current application of DTs modeling in various industries.The application of 3D DTs modeling in the􀀀elds of smartmanufacturing,smart ecology,smart transportation,and smart buildings in smart cities is analyzed in detail,and the current limitations are summarized.It is found that the 3D modeling technology in DTs has broad prospects for development and has a huge impact on all walks of life and even human lifestyles.At the same time,the development of DTs modeling relies on the development and support capabilities of mature technologies such as Big Data,Internet of Things,Cloud Computing,Articial Intelligence,and game technology.Therefore,although some results have been achieved,there are still limitations.This work aims to provide a good theoretical support for the further development of 3D DTs modeling. 展开更多
关键词 digital twins 3d modeling smart manufacturing smart city smart buildings
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